{
	"name":"lel03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"PVL30_003793 ABD1; mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"PVL30_002689 CDC28; Cyclin-dependent kinase catalytic subunit\tK04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22]"
					},
					{
						"name":"PVL30_000586 KIN28; TFIIH complex serine\/threonine-protein kinase subunit kin28\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"PVL30_004411 CEG1; Dcp1p-Dcp2p decapping enzyme complex alpha subunit\tK00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]"
					},
					{
						"name":"PVL30_000091 CET1; mRNA-capping enzyme subunit beta\tK01098 CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74]"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"PVL30_000629 cbc1; Nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"PVL30_001769 CBC2; nuclear cap binding complex subunit\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)"
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"PVL30_002286 CLP1; Cleavage polyadenylation factor subunit clp1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"PVL30_005520 uncharacterized protein\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"PVL30_004196 CFT1; mRNA cleavage and polyadenylation factor subunit\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"PVL30_002069 uncharacterized protein\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"PVL30_001848 YSH1; endoribonuclease ysh1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"PVL30_000985 YTH1; RNA-binding component of cleavage and polyadenylation factor\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"PVL30_004054 MPE1; Protein mpe1\tK15541 MPE1; protein MPE1"
					},
					{
						"name":"PVL30_000752 PFS2; pre-mRNA cleavage and polyadenylation factor (CPF) complex subunit\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"PVL30_000801 SWD2; member of Set1p complex, histone methyl transferase\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"PVL30_002559 GLC7; type 1 serine\/threonine-protein phosphatase catalytic subunit glc7\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"PVL30_002570 pzh1; serine\/threonine protein phosphatase Pzh1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"PVL30_005665 uncharacterized protein\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"PVL30_000243 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"PVL30_001562 uncharacterized protein\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"PVL30_002433 uncharacterized protein\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"PVL30_005107 uncharacterized protein\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"PVL30_002829 smb1; Small nuclear ribonucleoprotein-associated protein B\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"PVL30_004641 SMD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"PVL30_002069 uncharacterized protein\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"PVL30_001848 YSH1; endoribonuclease ysh1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"PVL30_001562 uncharacterized protein\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"PVL30_002433 uncharacterized protein\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"PVL30_005107 uncharacterized protein\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"PVL30_004845 SPT4; transcription elongation factor spt4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"PVL30_001098 SPT5; transcription elongation factor spt5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"PVL30_000087 KAR4; regulatory protein\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"PVL30_004582 PAP1; polynucleotide adenylyltransferase\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing"
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"PVL30_005240 uncharacterized protein\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"PVL30_001386 NAB2; mRNA-binding protein nab2\tK23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"PVL30_000378 uncharacterized protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"PVL30_003528 YRA1; RNA-binding RNA annealing protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"PVL30_004027 SUB2; Suppressor of the cold-sensitive snRNP biogenesis mutant brr1-1\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_001700 FAL1; RNA helicase\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_004612 uncharacterized protein\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"PVL30_000972 RLR1; THO2 plays a role in transcriptional elongation\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"PVL30_004603 uncharacterized protein\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"PVL30_000378 uncharacterized protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"PVL30_003528 YRA1; RNA-binding RNA annealing protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"PVL30_001721 uncharacterized protein\tK18712 HPR1; THO complex subunit HPR1"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"PVL30_000545 uncharacterized protein\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"PVL30_000928 uncharacterized protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"PVL30_003857 SUS1; SAGA histone acetylase and TREX-2 complexes component\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"PVL30_002858 CDC31; Calcium-binding component of the spindle pole body (SPB) half-bridge\tK16466 CETN3; centrin-3"
					},
					{
						"name":"PVL30_000720 SAC3; actin cytoskeleton and mitosis protein\tK23719 SAC3; nuclear mRNA export protein SAC3"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"PVL30_004088 MLP1; Protein mlp1\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"PVL30_003835 GLE2; RNA export factor gle2\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"PVL30_002004 SEC13; GTPase-activating protein S13\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"PVL30_003500 NUP85; Nucleoporin nup85\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"PVL30_000107 NUP57; Nucleoporin nup57\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"PVL30_001284 NSP1; FG-nucleoporin nsp1\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"PVL30_001120 NIC96; nuclear pore complex subunit\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"PVL30_003548 uncharacterized protein\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"PVL30_004255 NUP84; Nucleoporin nup84\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"PVL30_000608 uncharacterized protein\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"PVL30_000410 uncharacterized protein\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"PVL30_001698 uncharacterized protein\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"PVL30_004055 uncharacterized protein\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"PVL30_000043 uncharacterized protein\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"PVL30_002907 NUP49; Nucleoporin nup49\/NSP49 (Nuclear pore protein nup49\/NSP49)\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"PVL30_005367 NDC1; Nuclear pore complex subunit\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"PVL30_001900 SEH1; epoxide hydrolase, soluble (sEH)\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"PVL30_003787 uncharacterized protein\tK18715 NUP159; nucleoporin NUP159"
					},
					{
						"name":"PVL30_003733 uncharacterized protein\tK18716 NUP42; nucleoporin NUP42"
					},
					{
						"name":"PVL30_004258 uncharacterized protein\tK18717 ASM4; nucleoporin ASM4"
					},
					{
						"name":"PVL30_005722 NUP82; Nucleoporin nup82\tK18719 NUP82; nucleoporin NUP82"
					},
					{
						"name":"PVL30_004448 uncharacterized protein\tK18720 NUP145; nucleoporin NUP145"
					},
					{
						"name":"PVL30_005652 uncharacterized protein\tK18721 NUP1; nucleoporin NUP1"
					},
					{
						"name":"PVL30_004514 uncharacterized protein\tK18722 NUP2; nucleoporin NUP2"
					},
					{
						"name":"PVL30_002858 CDC31; Calcium-binding component of the spindle pole body (SPB) half-bridge\tK16466 CETN3; centrin-3"
					},
					{
						"name":"PVL30_001965 uncharacterized protein\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"PVL30_002855 MEX67; nuclear mRNA export, poly(A)+RNA binding protein\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"PVL30_003174 MTR2; mRNA transport regulator mtr2\tK14543 MTR2; mRNA transport regulator MTR2"
					},
					{
						"name":"PVL30_000959 uncharacterized protein\tK18724 POM34; nucleoporin POM34"
					},
					{
						"name":"PVL30_001180 uncharacterized protein\tK18725 POM152; nucleoporin POM152"
					},
					{
						"name":"PVL30_000313 uncharacterized protein\tK14017 SNL1; HSP70 co-chaperone SNL1"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"PVL30_001856 GSP1; GTP-binding nuclear protein gsp1\/Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"PVL30_004265 ucp10; UBX domain-containing protein 10\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"PVL30_000380 CDC48; AAA ATPase cdc48\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"PVL30_000457 CRM1; Karyopherin transporter\tK14290 XPO1; exportin-1"
					},
					{
						"name":"PVL30_003757 rna1; Ran GAP Rna1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"PVL30_003116 uncharacterized protein\tK14651 TAF15; transcription initiation factor TFIID subunit 15"
					},
					{
						"name":"PVL30_000525 NTF2; Nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"PVL30_002360 TIF45; eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"PVL30_001377 TIF1; translation initiation factor eIF4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"PVL30_003425 uncharacterized protein\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"PVL30_005483 TIF3; Eukaryotic translation initiation factor 4B\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"PVL30_003577 DED1; DEAD-box ATP-dependent RNA helicase\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_004485 SMY2; kinesin-like protein\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"PVL30_001520 PAB1; Protein phosphatase PP2A regulatory subunit B\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"PVL30_002599 SKI2; Antiviral helicase ski2\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"PVL30_004805 SLH1; hydrophobin\tK18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6]"
					},
					{
						"name":"PVL30_004129 TMA20; translation machinery-associated protein 20\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"PVL30_003985 TMA22; Translation machinery-associated protein 22\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex"
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"PVL30_003711 uncharacterized protein\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"PVL30_000220 DOM34; Translation factor pelota\tK06965 PELO; protein pelota"
					},
					{
						"name":"PVL30_003339 uncharacterized protein\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"PVL30_005003 uncharacterized protein\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"PVL30_003743 DBP5; RNA helicase required for poly(A+) mRNA export\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_004477 SYF1; pre-mRNA-splicing factor syf1\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"PVL30_003399 uncharacterized protein\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"PVL30_005151 RCC1; Regulator of chromosome condensation\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"PVL30_005091 GBP2; g-strand binding protein\tK28506 GBP2; serine\/arginine (SR)-type shuttling mRNA binding protein"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"PVL30_000912 ERF1; translation termination factor eRF1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"PVL30_003348 SUP35; translation termination factor GTPase eRF3\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"PVL30_004562 NAM7; ATP-dependent RNA helicase\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"PVL30_001250 NMD2; mRNA decay protein\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"PVL30_002232 uncharacterized protein\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"PVL30_002247 PPH21; protein phosphatase type 2A\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"PVL30_003843 TPD3; protein phosphatase 2A structural subunit\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"PVL30_000886 CDC55; protein phosphatase 2A regulatory subunit cdc55\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"PVL30_001866 RTS1; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"PVL30_004485 SMY2; kinesin-like protein\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"PVL30_005730 SHE3; mother-specific HO expression\tK18737 SHE3; SWI5-dependent HO expression protein 3"
					},
					{
						"name":"PVL30_000614 puf6; Pumilio y domain member 6\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"PVL30_005615 HEK2; RNA binding protein, heterogenous nuclear RNP-K like protein\tK18738 HEK; heterogeneous nuclear rnp K-like protein"
					},
					{
						"name":"PVL30_005725 PBP2; PAB1 binding protein\tK18738 HEK; heterogeneous nuclear rnp K-like protein"
					},
					{
						"name":"PVL30_003045 MYO2; Myosin type-2 heavy chain 1\tK10357 MYO5; myosin V"
					},
					{
						"name":"PVL30_003173 ASH1; DNA-binding transcription repressor\tK18658 ASH1; transcriptional regulatory protein ASH1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals"
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"PVL30_000573 TEF1_1; translation elongation factor EF-1 alpha\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"PVL30_003186 TEF1_3; translation elongation factor EF-1 alpha\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"PVL30_003655 TEF4_1; elongation factor EF-1 gamma subunit\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"PVL30_004631 TEF4_2; elongation factor EF-1 gamma subunit\tK03233 EEF1G; elongation factor 1-gamma"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"PVL30_004856 SSD1; Translational repressor\tK18748 SSD1; protein SSD1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"PVL30_002913 exo2; exonuclease II Exo2\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"PVL30_002360 TIF45; eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"PVL30_004562 NAM7; ATP-dependent RNA helicase\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"PVL30_003577 DED1; DEAD-box ATP-dependent RNA helicase\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_000840 DHH1; DExD\/H-box ATP-dependent RNA helicase dhh1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_000593 uncharacterized protein\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"PVL30_000603 uncharacterized protein\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"PVL30_000539 PKA1; camp-dependent protein kinase catalytic subunit\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"PVL30_003298 TPK2_3; cAMP-dependent protein kinase catalytic subunit\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"PVL30_005333 uncharacterized protein\tK18757 LARP1; la-related protein 1"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"PVL30_002593 DCP2; mRNA-decapping enzyme subunit 2\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"PVL30_001718 DCP1; mRNA-decapping enzyme subunit 1\tK12612 DCP1; mRNA-decapping enzyme subunit 1"
					},
					{
						"name":"PVL30_002436 uncharacterized protein\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"PVL30_002834 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"PVL30_002501 uncharacterized protein\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"PVL30_000042 LSM6; U4\/U6-U5 snRNP complex subunit lsm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"PVL30_004664 LSM7; Sm-like protein lsm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"PVL30_003045 MYO2; Myosin type-2 heavy chain 1\tK10357 MYO5; myosin V"
					},
					{
						"name":"PVL30_002471 TUB1; alpha-tubulin\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"PVL30_005709 CDC39; CCR4-NOT core subunit cdc39\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"PVL30_001437 CDC36; transcriptional regulator\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"PVL30_000368 NOT5; general negative regulator of transcription subunit 5\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"PVL30_001131 NOT3; CCR4-NOT core subunit\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"PVL30_000270 NOT4; transcriptional repressor general negative regulator of transcription subunit 4\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"PVL30_000374 CCR4; Glucose-repressible alcohol dehydrogenase transcriptional effector\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"PVL30_000375 uncharacterized protein\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"PVL30_005737 POP2; CCR4-NOT core DEDD RNase subunit\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"PVL30_003083 PAN2; poly(A)-specific ribonuclease\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"PVL30_004790 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"PVL30_004173 PAT1; DNA topoisomerase 2-associated protein pat1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"PVL30_001068 EDC1; enhancer of mRNA decapping\tK18759 EDC1_2; enhancer of mRNA-decapping protein 1\/2"
					},
					{
						"name":"PVL30_004447 EDC3; enhancer of mRNA decapping\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"PVL30_001250 NMD2; mRNA decay protein\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"PVL30_002232 uncharacterized protein\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"PVL30_001395 RPB7; DNA-directed RNA polymerase II subunit\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"PVL30_003625 PUB1; E3 ubiquitin-protein ligase pub1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"PVL30_001520 PAB1; Protein phosphatase PP2A regulatory subunit B\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"PVL30_001593 uncharacterized protein\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"PVL30_005163 PRT1; Translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"PVL30_001377 TIF1; translation initiation factor eIF4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"PVL30_001700 FAL1; RNA helicase\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_005483 TIF3; Eukaryotic translation initiation factor 4B\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"PVL30_003425 uncharacterized protein\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"PVL30_005022 ASC1; G-protein beta subunit and guanine dissociation inhibitor for Gpa2p\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"PVL30_002855 MEX67; nuclear mRNA export, poly(A)+RNA binding protein\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"PVL30_000060 HDA1; Histone deacetylase hda1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"PVL30_001718 DCP1; mRNA-decapping enzyme subunit 1\tK12612 DCP1; mRNA-decapping enzyme subunit 1"
					},
					{
						"name":"PVL30_002593 DCP2; mRNA-decapping enzyme subunit 2\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"PVL30_000840 DHH1; DExD\/H-box ATP-dependent RNA helicase dhh1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"PVL30_001068 EDC1; enhancer of mRNA decapping\tK18759 EDC1_2; enhancer of mRNA-decapping protein 1\/2"
					},
					{
						"name":"PVL30_004447 EDC3; enhancer of mRNA decapping\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"PVL30_004173 PAT1; DNA topoisomerase 2-associated protein pat1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"PVL30_002436 uncharacterized protein\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"PVL30_002834 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"PVL30_002501 uncharacterized protein\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"PVL30_000042 LSM6; U4\/U6-U5 snRNP complex subunit lsm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"PVL30_004664 LSM7; Sm-like protein lsm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"PVL30_002913 exo2; exonuclease II Exo2\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"PVL30_003889 RAT1; 5'-3' exoribonuclease 2\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"PVL30_004999 uncharacterized protein\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"PVL30_002015 uncharacterized protein\tK28513 SBP1; single-stranded nucleic acid-binding protein"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"PVL30_001815 CSL4; exosome 3'->5 exonuclease subunit ski4 (Csl4)\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"PVL30_004249 RRP4; exosome non-catalytic core subunit rrp4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"PVL30_001363 RRP40; exosome non-catalytic core subunit rrp40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"PVL30_003936 SKI6; Exosome non-catalytic core component\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"PVL30_001877 RRP46; exosome non-catalytic core subunit rrp46\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"PVL30_000209 MTR3; 3'-5'-exoribonuclease\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"PVL30_004259 RRP42; Exosome complex component rrp42\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"PVL30_003603 RRP45; 3'-5'-exoribonuclease\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"PVL30_003092 DIS3; exosome catalytic subunit dis3\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"PVL30_001750 RRP6; exosome nuclease subunit\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"PVL30_000821 uncharacterized protein\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"PVL30_000475 uncharacterized protein\tK12594 MPP6; M-phase phosphoprotein 6, fungi type"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"PVL30_001724 TRF5; Poly(A) polymerase\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"PVL30_000356 uncharacterized protein\tK12597 AIR1_2; protein AIR1\/2"
					},
					{
						"name":"PVL30_005297 MTR4; ATP-dependent RNA helicase mtr4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"PVL30_002599 SKI2; Antiviral helicase ski2\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"PVL30_000521 SKI3; Superkiller protein 3\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"PVL30_005721 rec14; Ski complex subunit Rec14\tK12601 SKI8; superkiller protein 8"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"PVL30_000374 CCR4; Glucose-repressible alcohol dehydrogenase transcriptional effector\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"PVL30_000375 uncharacterized protein\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"PVL30_005709 CDC39; CCR4-NOT core subunit cdc39\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"PVL30_001437 CDC36; transcriptional regulator\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"PVL30_000368 NOT5; general negative regulator of transcription subunit 5\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"PVL30_001131 NOT3; CCR4-NOT core subunit\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"PVL30_000270 NOT4; transcriptional repressor general negative regulator of transcription subunit 4\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"PVL30_005737 POP2; CCR4-NOT core DEDD RNase subunit\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"PVL30_005143 RCD1; Cell differentiation protein rcd1\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"PVL30_000627 CAF16; CCR4-NOT regulatory complex component\tK12608 CAF16; CCR4-NOT complex subunit CAF16"
					},
					{
						"name":"PVL30_000533 uncharacterized protein\tK12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"PVL30_003083 PAN2; poly(A)-specific ribonuclease\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"PVL30_004790 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"PVL30_004999 uncharacterized protein\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"PVL30_001484 VTS1; Flap-structured DNA-binding and RNA-binding protein\tK27407 VTS1; RNA-binding protein VTS1"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"PVL30_004433 uncharacterized protein\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"PVL30_005260 rex2; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"PVL30_000621 ENO1; phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"PVL30_004863 PFK1; 6-phosphofructokinase, alpha subunit\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"PVL30_005194 PFK2; phosphofructokinase beta-subunit\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"PVL30_001820 SSC1; Hsp70 ATPase ssc1\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"PVL30_005177 uncharacterized protein\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"PVL30_002923 HSP60; chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"PVL30_004249 RRP4; exosome non-catalytic core subunit rrp4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"PVL30_001815 CSL4; exosome 3'->5 exonuclease subunit ski4 (Csl4)\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"PVL30_003936 SKI6; Exosome non-catalytic core component\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"PVL30_004259 RRP42; Exosome complex component rrp42\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}