{
	"name":"lhh03016",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P"
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"LBH_0851 Ribonuclease Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"LBH_0874 tRNA nucleotidyltransferase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonuclease complex"
			},
			{
				"name":"tRNA splicing ligase complex"
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			},
			{
				"name":"tRNA import factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"LBH_1110 Proline-tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"LBH_0719 ileS; Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"LBH_1437 leuS; Leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"LBH_0179 Methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"LBH_1405 argS; Arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"LBH_0233 lysS; Lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"LBH_0839 aspS; Aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"LBH_0358 alaS; Alanine-tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"LBH_1036 asnC; asparaginyl-tRNA synthetase-like 2 (putative)\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"LBH_1345 thrS; Threonyl-tRNA synthetase 1\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"LBH_1454 Serine-tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"LBH_0295 cysS; Cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"LBH_0693 valS; Valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"LBH_0838 hisS; Histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"LBH_1321 pheS; Phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"LBH_1320 pheT; Phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"LBH_0165 Tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"LBH_0175 Tryptophanyl-tRNA synthetase II\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"LBH_0837 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				}
				]
			},
			{
				"name":"AARS associated factors",
				"children":[
				{
					"name":"LBH_1378 Diadenosine tetraphosphate (Ap4A) hydrolase related HIT family hydrolase\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases"
			},
			{
				"name":"Dihydorouridine synthases"
			},
			{
				"name":"Methylthiotransferase"
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"LBH_1373 trmB; tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"LBH_0274 truA; tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"LBH_1102 truB; tRNA pseudouridine synthase B\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"LBH_0675 Aminotransferase class V\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"LBH_0724 Putative aminotransferase class V ATase1\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Elongator complex"
			},
			{
				"name":"Elongator related proteins"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"LBH_0655 Sua5 family translation factor\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"LBH_1306 miaA; tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"LBH_1751 trmE; tRNA modification GTPase mnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"LBH_1750 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"TRAMP complex"
			},
			{
				"name":"Rapid tRNA decay (RTD) pathway factors"
			},
			{
				"name":"Other tRNA degradation factors"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"LBH_1753 rnpA; Ribonuclease P protein component\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"LBH_0851 Ribonuclease Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"LBH_0874 tRNA nucleotidyltransferase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonucleases"
			},
			{
				"name":"tRNA splicing ligases"
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"LBH_1437 leuS; Leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"LBH_1110 Proline-tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"LBH_0165 Tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"LBH_0175 Tryptophanyl-tRNA synthetase II\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"LBH_1345 thrS; Threonyl-tRNA synthetase 1\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"LBH_0719 ileS; Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"LBH_0233 lysS; Lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"LBH_0358 alaS; Alanine-tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"LBH_0693 valS; Valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"LBH_0179 Methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"LBH_1454 Serine-tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"LBH_0839 aspS; Aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"LBH_1063 glyQ; Glycyl-tRNA synthetase alpha chain\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]"
				},
				{
					"name":"LBH_1062 glyS; Glycyl-tRNA synthetase beta subunit\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]"
				},
				{
					"name":"LBH_0295 cysS; Cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"LBH_1405 argS; Arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"LBH_1321 pheS; Phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"LBH_1320 pheT; Phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"LBH_0838 hisS; Histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"LBH_1036 asnC; asparaginyl-tRNA synthetase-like 2 (putative)\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"LBH_0294 gltX; Glutamyl-tRNA synthetase\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"LBH_0837 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"LBH_0833 Transcriptional regulator\tK03976 ybaK; Cys-tRNA(Pro)\/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]"
				},
				{
					"name":"LBH_1326 YbaK\/prolyl-tRNA synthetase associated region\tK19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases",
				"children":[
				{
					"name":"LBH_0320 Cytidine\/deoxycytidylate deaminase, zinc-binding region\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]"
				}
				]
			},
			{
				"name":"Dihydorouridine synthases",
				"children":[
				{
					"name":"LBH_0232 tRNA-dihydrouridine synthase B\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				}
				]
			},
			{
				"name":"Methylthiotransferases"
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"LBH_0883 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO\tK04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]"
				},
				{
					"name":"LBH_1373 trmB; tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"LBH_1133 trmD; tRNA (guanine-N(1)-)-methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"LBH_1751 trmE; tRNA modification GTPase mnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"LBH_1058 Putative methyltransferase\tK06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]"
				},
				{
					"name":"LBH_0563 RNA methyltransferase, TrmH family, group 2\tK03216 trmL; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]"
				},
				{
					"name":"LBH_1323 TrmH family RNA methyltransferase\tK03437 spoU; RNA methyltransferase, TrmH family"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"LBH_0274 truA; tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"LBH_1102 truB; tRNA pseudouridine synthase B\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"LBH_0726 mnmA; tRNA-specific 2-thiouridylase mnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"LBH_0675 Aminotransferase class V\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"LBH_0724 Putative aminotransferase class V ATase1\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"LBH_1750 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"LBH_1306 miaA; tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"LBH_0676 putative tRNA sulfurtransferase\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				},
				{
					"name":"LBH_0228 tRNA(Ile)-lysidine synthase (TRNA(Ile)-lysidinesynthetase)\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"LBH_0332 Putative glycoprotein endopeptidase\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"LBH_0655 Sua5 family translation factor\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"LBH_0334 Metal-dependent protease with chaperone activity\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"LBH_0604 Putative ATPase or kinase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"LBH_1330 Nucleotidyltransferase\tK27343 tmcAL; tRNAmet cytidine acetate ligase [EC:6.3.1.22]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"LBH_1448 Ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
			}
			]
		}
		]
	}
	]
}
