{
	"name":"lhil03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins"
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"G8J22_02736 cysL_2; HTH-type transcriptional regulator CysL\tK21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"G8J22_02212 ccpN; Transcriptional repressor CcpN\tK23774 ccpN; DeoR family transcriptional regulator, catabolite repression regulator"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"G8J22_00136 melR_1; HTH-type transcriptional repressor MelR\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_00499 ccpA_1; Catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_00606 ccpA_2; Catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_00679 malR; HTH-type transcriptional regulator MalR\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_00845 ccpA_3; Catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_00988 rbsR; Ribose operon repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_01228 ccpA_4; Catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_02438 melR_3; HTH-type transcriptional repressor MelR\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"G8J22_01507 kdgR_2; HTH-type transcriptional regulator KdgR\tK02525 kdgR; LacI family transcriptional regulator, kdg operon repressor"
				},
				{
					"name":"G8J22_02133 purR_2; HTH-type transcriptional repressor PurR\tK03484 scrR; LacI family transcriptional regulator, sucrose operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"G8J22_02485 araR; Arabinose metabolism transcriptional repressor\tK02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor"
				},
				{
					"name":"G8J22_02512 gmuR; HTH-type transcriptional regulator GmuR\tK03492 gmuR; GntR family transcriptional regulator, regulator of glucomannan utilization"
				},
				{
					"name":"G8J22_01831 nagR; HTH-type transcriptional repressor NagR\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				}
				]
			},
			{
				"name":"TetR\/AcrR family"
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"G8J22_00348 lrpC_1; HTH-type transcriptional regulator LrpC\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"G8J22_00682 lrpC_2; HTH-type transcriptional regulator LrpC\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				}
				]
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"G8J22_01653 ohrR; Organic hydroperoxide resistance transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"G8J22_01578 glnR; HTH-type transcriptional regulator GlnR\tK03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor"
				},
				{
					"name":"G8J22_01492 adhR; HTH-type transcriptional regulator AdhR\tK21745 adhR; MerR family transcriptional regulator, aldehyde-responsive regulator"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"G8J22_02120 zur; Zinc-specific metallo-regulatory protein\tK02076 zurR; Fur family transcriptional regulator, zinc uptake regulator"
				},
				{
					"name":"G8J22_02287 perR; Peroxide operon regulator\tK09825 perR; Fur family transcriptional regulator, peroxide stress response regulator"
				}
				]
			},
			{
				"name":"IclR family"
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"G8J22_00415 crp; CRP-like cAMP-activated global transcriptional regulator\tK21562 flp; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"G8J22_00461 ntcA; Global nitrogen regulator\tK21828 arcR; CRP\/FNR family transcriptional regulator, arginine deiminase pathway regulator"
				}
				]
			},
			{
				"name":"Rrf2 family"
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"G8J22_01503 hypothetical protein\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"G8J22_00817 czrA; HTH-type transcriptional repressor CzrA\tK22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family",
				"children":[
				{
					"name":"G8J22_02300 sutR; HTH-type transcriptional regulator SutR\tK23779 sutR; XRE family transcriptional regulator, regulator of sulfur utilization"
				}
				]
			},
			{
				"name":"PadR family",
				"children":[
				{
					"name":"G8J22_00396 hypothetical protein\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"G8J22_02042 hypothetical protein\tK10947 K10947; PadR family transcriptional regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"G8J22_02045 mntR; HTH-type transcriptional regulator MntR\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"G8J22_01945 ybbH; putative HTH-type transcriptional regulator YbbH\tK19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator"
				},
				{
					"name":"G8J22_01949 birA; Bifunctional ligase\/repressor BirA\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"G8J22_01885 purR_1; Pur operon repressor\tK09685 purR; HTH-type transcriptional regulator, purine operon repressor"
				},
				{
					"name":"G8J22_02158 hypothetical protein\tK02647 cdaR; carbohydrate diacid regulator"
				},
				{
					"name":"G8J22_01764 rex; Redox-sensing transcriptional repressor Rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"G8J22_01480 hypothetical protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"G8J22_02408 hypothetical protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"G8J22_02053 hypothetical protein\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"G8J22_00253 pucR; Purine catabolism regulatory protein\tK09684 pucR; PucR family transcriptional regulator, purine catabolism regulatory protein"
				},
				{
					"name":"G8J22_00781 spo0J; Stage 0 sporulation protein J\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"G8J22_00457 argR_1; Arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"G8J22_01560 argR_2; Arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"G8J22_01273 hrcA; Heat-inducible transcription repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"G8J22_00416 tenA_1; Aminopyrimidine aminohydrolase\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]"
				},
				{
					"name":"G8J22_00437 tenA_2; Aminopyrimidine aminohydrolase\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]"
				},
				{
					"name":"G8J22_01476 tenA_3; Aminopyrimidine aminohydrolase\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]"
				},
				{
					"name":"G8J22_02025 ctsR; Transcriptional regulator CtsR\tK03708 ctsR; transcriptional regulator of stress and heat shock response"
				},
				{
					"name":"G8J22_01964 deoR; Deoxyribonucleoside regulator\tK05346 deoR; deoxyribonucleoside regulator"
				},
				{
					"name":"G8J22_01451 pyrR; Bifunctional protein pyrR\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"G8J22_01620 nrdR; Transcriptional repressor NrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"G8J22_00948 mraZ; Transcriptional regulator MraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}