{
	"name":"lht03016",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"122505976 ribonucleases P\/MRP protein subunit POP1\tK01164 POP1; ribonuclease P\/MRP protein subunit POP1 [EC:3.1.26.5]"
				},
				{
					"name":"122499910 ribonuclease P protein subunit p29\tK03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]"
				},
				{
					"name":"122504772 uncharacterized protein LOC122504772\tK03537 POP5; ribonuclease P\/MRP protein subunit POP5 [EC:3.1.26.5]"
				},
				{
					"name":"122507957 protein GAMETOPHYTE DEFECTIVE 1 isoform X1\tK03539 RPP1; ribonuclease P\/MRP protein subunit RPP1 [EC:3.1.26.5]"
				},
				{
					"name":"122510896 ribonuclease P protein subunit p40-like\tK14530 RPP40; ribonucleases P\/MRP protein subunit RPP40 [EC:3.1.26.5]"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"122498738 ribonuclease Oy-like\tK01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"122511637 CCA tRNA nucleotidyltransferase 1, mitochondrial isoform X1\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonuclease complex",
				"children":[
				{
					"name":"122507042 tRNA-splicing endonuclease subunit Sen2\tK15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]"
				},
				{
					"name":"122506599 tRNA-splicing endonuclease subunit Sen34\tK15323 TSEN34; tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16]"
				},
				{
					"name":"122506576 uncharacterized protein LOC122506576\tK15324 TSEN15; tRNA-splicing endonuclease subunit Sen15"
				}
				]
			},
			{
				"name":"tRNA splicing ligase complex",
				"children":[
				{
					"name":"122504807 RNA-splicing ligase RtcB homolog\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				},
				{
					"name":"122510106 RNA transcription, translation and transport factor protein\tK15433 CGI99; RLL motif containing protein 1"
				},
				{
					"name":"122506550 ATP-dependent RNA helicase Ddx1\tK13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]"
				},
				{
					"name":"122503546 protein archease-like\tK24956 ZBTB8OS; protein archease"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors",
				"children":[
				{
					"name":"122506041 GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
				},
				{
					"name":"122505539 exportin-1\tK14290 XPO1; exportin-1"
				},
				{
					"name":"122504420 exportin-5\tK14289 XPO5; exportin-5"
				},
				{
					"name":"122509867 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"122512127 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"122511858 N-terminal kinase-like protein\tK08876 SCYL1; SCY1-like protein 1"
				},
				{
					"name":"122508842 GTP-binding protein 1\tK24887 GTPBP1; GTP-binding protein 1"
				}
				]
			},
			{
				"name":"tRNA import factors",
				"children":[
				{
					"name":"122499673 transportin-3 isoform X1\tK15436 TRPO3; transportin-3"
				}
				]
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"122503324 bifunctional glutamate\/proline--tRNA ligase isoform X1\tK14163 EPRS; bifunctional glutamyl\/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]"
				},
				{
					"name":"122501255 probable glutamate--tRNA ligase, mitochondrial\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"122509522 probable proline--tRNA ligase, mitochondrial\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"122509162 isoleucine--tRNA ligase, cytoplasmic\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122509425 isoleucine--tRNA ligase, mitochondrial\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122498472 probable leucine--tRNA ligase, mitochondrial\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122504845 leucine--tRNA ligase, cytoplasmic\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122497579 methionine--tRNA ligase, mitochondrial-like\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"122500162 methionine--tRNA ligase, cytoplasmic\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"122505216 probable glutamine--tRNA ligase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"122504986 probable arginine--tRNA ligase, cytoplasmic\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122512446 probable arginine--tRNA ligase, mitochondrial isoform X1\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122508117 lysine--tRNA ligase isoform X1\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"122504002 aspartate--tRNA ligase, cytoplasmic\tK22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"122511424 aspartate--tRNA ligase, mitochondrial\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"122506864 eukaryotic translation elongation factor 1 epsilon-1\tK15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"122500667 alanine--tRNA ligase, cytoplasmic isoform X1\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"122499752 asparagine--tRNA ligase, cytoplasmic\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"122512350 probable asparagine--tRNA ligase, mitochondrial\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"122497835 glycine--tRNA ligase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"122509468 threonine--tRNA ligase 1, cytoplasmic isoform X1\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"122503749 serine--tRNA ligase, mitochondrial\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122504445 serine--tRNA ligase, cytoplasmic\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122502602 cysteine--tRNA ligase, cytoplasmic\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"122507907 probable cysteine--tRNA ligase, mitochondrial\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"122508990 valine--tRNA ligase-like isoform X1\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"122510358 valine--tRNA ligase isoform X1\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"122512478 histidine--tRNA ligase, cytoplasmic isoform X1\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"122498619 probable phenylalanine--tRNA ligase, mitochondrial\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122509446 phenylalanine--tRNA ligase alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122504823 phenylalanine--tRNA ligase beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"122508969 tyrosine--tRNA ligase, mitochondrial\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122512486 tyrosine--tRNA ligase, cytoplasmic isoform X1\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122510080 tryptophan--tRNA ligase, cytoplasmic\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"122512585 tryptophan--tRNA ligase, mitochondrial\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"122508415 D-aminoacyl-tRNA deacylase 1\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				}
				]
			},
			{
				"name":"AARS associated factors",
				"children":[
				{
					"name":"122503327 tRNA selenocysteine 1-associated protein 1 isoform X1\tK25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1"
				},
				{
					"name":"122510316 histidine triad nucleotide-binding protein 1\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"122502842 histidine triad nucleotide-binding protein 3-like isoform X1\tK12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases",
				"children":[
				{
					"name":"122511624 tRNA-specific adenosine deaminase 2\tK15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]"
				}
				]
			},
			{
				"name":"Dihydorouridine synthases",
				"children":[
				{
					"name":"122509255 tRNA-dihydrouridine(16\/17) synthase [NAD(P)(+)]-like\tK05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]"
				},
				{
					"name":"122504479 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like\tK05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]"
				},
				{
					"name":"122511013 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like\tK05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]"
				},
				{
					"name":"122501511 tRNA-dihydrouridine(20a\/20b) synthase [NAD(P)+]-like\tK05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]"
				}
				]
			},
			{
				"name":"Methylthiotransferase",
				"children":[
				{
					"name":"122502046 CDK5RAP1-like protein\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"122507796 threonylcarbamoyladenosine tRNA methylthiotransferase\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"122504363 probable tRNA (guanine(26)-N(2))-dimethyltransferase isoform X1\tK00555 TRMT1; tRNA (guanine26-N2\/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]"
				},
				{
					"name":"122510236 tRNA (uracil-5-)-methyltransferase homolog A\tK15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"122505570 tRNA (cytosine(34)-C(5))-methyltransferase\tK15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]"
				},
				{
					"name":"122504247 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6\tK21971 NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]"
				},
				{
					"name":"122499902 tRNA (guanine(37)-N1)-methyltransferase\tK15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"122507874 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A\tK07442 TRM61; tRNA (adenine57-N1\/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]"
				},
				{
					"name":"122508301 putative tRNA (cytidine(32)\/guanosine(34)-2'-O)-methyltransferase isoform X1\tK14864 FTSJ1; tRNA (cytidine32\/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]"
				},
				{
					"name":"122501970 tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"122500892 tRNA N(3)-methylcytidine methyltransferase METTL2\tK24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]"
				},
				{
					"name":"122512327 tRNA N(3)-methylcytidine methyltransferase METTL6 isoform X1\tK00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]"
				},
				{
					"name":"122509640 alkylated DNA repair protein alkB homolog 8\tK10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]"
				},
				{
					"name":"122498481 uncharacterized protein LOC122498481 isoform X1\tK28867 TRMT9B; tRNA methyltransferase 9B [EC:2.1.1.-]"
				},
				{
					"name":"122508258 tRNA methyltransferase 10 homolog A\tK15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]"
				},
				{
					"name":"122505457 tRNA (guanine(10)-N2)-methyltransferase homolog\tK15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]"
				},
				{
					"name":"122500343 tRNA:m(4)X modification enzyme TRM13 homolog\tK15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]"
				},
				{
					"name":"122510391 probable tRNA (uracil-O(2)-)-methyltransferase\tK15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]"
				},
				{
					"name":"122504954 multifunctional methyltransferase subunit TRM112-like protein\tK15448 TRM112; multifunctional methyltransferase subunit TRM112"
				},
				{
					"name":"122509329 tRNA (cytosine(38)-C(5))-methyltransferase\tK15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]"
				},
				{
					"name":"122512995 tRNA (adenine(37)-N6)-methyltransferase\tK22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"122501632 pre-miRNA 5'-monophosphate methyltransferase\tK25191 BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"122502876 tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"122511262 tRNA pseudouridine(38\/39) synthase\tK01855 PUS3; tRNA pseudouridine38\/39 synthase [EC:5.4.99.45]"
				},
				{
					"name":"122498200 tRNA pseudouridine synthase Pus10 isoform X1\tK07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"122501347 mitochondrial tRNA-specific 2-thiouridylase 1 isoform X1\tK21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]"
				},
				{
					"name":"122504287 cytoplasmic tRNA 2-thiolation protein 1\tK14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]"
				},
				{
					"name":"122501211 cysteine desulfurase, mitochondrial\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"122499233 ubiquitin-related modifier 1\tK12161 URM1; ubiquitin related modifier 1"
				},
				{
					"name":"122508412 adenylyltransferase and sulfurtransferase MOCS3\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex",
				"children":[
				{
					"name":"122499100 EKC\/KEOPS complex subunit TP53RK\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
				},
				{
					"name":"122503082 probable tRNA N6-adenosine threonylcarbamoyltransferase\tK01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				},
				{
					"name":"122512338 probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial\tK01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				}
				]
			},
			{
				"name":"Elongator complex",
				"children":[
				{
					"name":"122504396 putative elongator complex protein 1\tK11373 ELP1; elongator complex protein 1"
				},
				{
					"name":"122507717 probable elongator complex protein 2\tK11374 ELP2; elongator complex protein 2"
				},
				{
					"name":"122507965 elongator complex protein 3\tK07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]"
				},
				{
					"name":"122502644 elongator complex protein 4\tK11375 ELP4; elongator complex protein 4"
				},
				{
					"name":"122500135 elongator complex protein 6\tK11377 ELP6; elongator complex protein 6"
				}
				]
			},
			{
				"name":"Elongator related proteins",
				"children":[
				{
					"name":"122498836 protein KTI12 homolog isoform X1\tK15456 KTI12; protein KTI12"
				}
				]
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"122500194 yrdC domain-containing protein, mitochondrial\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"122508386 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"122499889 tRNA modification GTPase GTPBP3, mitochondrial isoform X1\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"122509099 protein MTO1 homolog, mitochondrial\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"122502922 queuine tRNA-ribosyltransferase catalytic subunit\tK00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]"
				},
				{
					"name":"122498987 queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1\tK15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit"
				},
				{
					"name":"122506033 inactive selenide, water dikinase-like protein\tK01008 selD; selenide, water dikinase [EC:2.7.9.3]"
				},
				{
					"name":"122499668 probable tRNA(His) guanylyltransferase\tK10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]"
				},
				{
					"name":"122501398 arginyl-tRNA--protein transferase 1\tK00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]"
				},
				{
					"name":"122507819 DALR anticodon-binding domain-containing protein 3\tK24973 DALRD3; DALR anticodon-binding domain-containing protein 3"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"TRAMP complex",
				"children":[
				{
					"name":"122507680 terminal nucleotidyltransferase 4B-like\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
				},
				{
					"name":"122504376 exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
				}
				]
			},
			{
				"name":"Rapid tRNA decay (RTD) pathway factors",
				"children":[
				{
					"name":"122507915 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
				},
				{
					"name":"122511856 5'-3' exoribonuclease 2 homolog\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
				},
				{
					"name":"122510049 3'(2'),5'-bisphosphate nucleotidase 1\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				}
				]
			},
			{
				"name":"Other tRNA degradation factors"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P"
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"122498738 ribonuclease Oy-like\tK01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"122511637 CCA tRNA nucleotidyltransferase 1, mitochondrial isoform X1\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonucleases"
			},
			{
				"name":"tRNA splicing ligases",
				"children":[
				{
					"name":"122504807 RNA-splicing ligase RtcB homolog\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"122498472 probable leucine--tRNA ligase, mitochondrial\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122504845 leucine--tRNA ligase, cytoplasmic\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122509522 probable proline--tRNA ligase, mitochondrial\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"122508969 tyrosine--tRNA ligase, mitochondrial\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122512486 tyrosine--tRNA ligase, cytoplasmic isoform X1\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122510080 tryptophan--tRNA ligase, cytoplasmic\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"122512585 tryptophan--tRNA ligase, mitochondrial\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"122509468 threonine--tRNA ligase 1, cytoplasmic isoform X1\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"122509162 isoleucine--tRNA ligase, cytoplasmic\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122509425 isoleucine--tRNA ligase, mitochondrial\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122508117 lysine--tRNA ligase isoform X1\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"122500667 alanine--tRNA ligase, cytoplasmic isoform X1\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"122508990 valine--tRNA ligase-like isoform X1\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"122510358 valine--tRNA ligase isoform X1\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"122497579 methionine--tRNA ligase, mitochondrial-like\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"122500162 methionine--tRNA ligase, cytoplasmic\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"122503749 serine--tRNA ligase, mitochondrial\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122504445 serine--tRNA ligase, cytoplasmic\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122511424 aspartate--tRNA ligase, mitochondrial\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"122502602 cysteine--tRNA ligase, cytoplasmic\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"122507907 probable cysteine--tRNA ligase, mitochondrial\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"122501255 probable glutamate--tRNA ligase, mitochondrial\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"122505216 probable glutamine--tRNA ligase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"122504986 probable arginine--tRNA ligase, cytoplasmic\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122512446 probable arginine--tRNA ligase, mitochondrial isoform X1\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122498619 probable phenylalanine--tRNA ligase, mitochondrial\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122509446 phenylalanine--tRNA ligase alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122504823 phenylalanine--tRNA ligase beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"122512478 histidine--tRNA ligase, cytoplasmic isoform X1\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"122499752 asparagine--tRNA ligase, cytoplasmic\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"122512350 probable asparagine--tRNA ligase, mitochondrial\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"122508415 D-aminoacyl-tRNA deacylase 1\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases"
			},
			{
				"name":"Dihydorouridine synthases"
			},
			{
				"name":"Methylthiotransferases",
				"children":[
				{
					"name":"122502046 CDK5RAP1-like protein\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"122507796 threonylcarbamoyladenosine tRNA methylthiotransferase\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"122501970 tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"122499889 tRNA modification GTPase GTPBP3, mitochondrial isoform X1\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"122512995 tRNA (adenine(37)-N6)-methyltransferase\tK22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"122502876 tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"122501211 cysteine desulfurase, mitochondrial\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex",
				"children":[
				{
					"name":"122499100 EKC\/KEOPS complex subunit TP53RK\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
				},
				{
					"name":"122503082 probable tRNA N6-adenosine threonylcarbamoyltransferase\tK01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				},
				{
					"name":"122512338 probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial\tK01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				}
				]
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"122509099 protein MTO1 homolog, mitochondrial\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"122508386 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"122510395 6-pyruvoyl tetrahydrobiopterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"122506033 inactive selenide, water dikinase-like protein\tK01008 selD; selenide, water dikinase [EC:2.7.9.3]"
				},
				{
					"name":"122500194 yrdC domain-containing protein, mitochondrial\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"122499056 polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
			}
			]
		}
		]
	}
	]
}