{
	"name":"lhu03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"105671345 obe; activating signal cointegrator 1 complex subunit 3\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"105674984 Tdg; uncharacterized protein Tdg isoform X1\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"105679748 G\/T mismatch-specific thymine DNA glycosylase-like isoform X1\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"105670507 DNA-3-methyladenine glycosylase-like isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"105678652 Smug; single-strand selective monofunctional uracil DNA glycosylase\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"105672263 Ogg1; N-glycosylase\/DNA lyase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"105674101 Nthl1; endonuclease III-like protein 1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"105678358 Rrp1; exodeoxyribonuclease isoform X1\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"105668277 PolD1; DNA polymerase delta catalytic subunit isoform X1\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"105675392 DNA polymerase delta subunit 2-like\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"105679854 DNA polymerase delta subunit 2-like\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"105669168 DNA polymerase delta subunit 3-like\tK03504 POLD3; DNA polymerase delta subunit 3"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"105677922 PolE1; DNA polymerase epsilon catalytic subunit 1 isoform X1\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"105679310 PolE2; DNA polymerase epsilon subunit 2\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"105669228 Chrac-14; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"105671464 PolE4; DNA polymerase epsilon subunit 4\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"105676428 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105678301 Fen1; flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"105673270 DNAlig1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"105674311 DNA polymerase beta-like\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"105675700 XRCC1; DNA repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"105672374 DNAlig3; DNA ligase 3 isoform X3\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"105677828 probable tyrosyl-DNA phosphodiesterase\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"105677829 probable tyrosyl-DNA phosphodiesterase\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"105672859 aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"105672044 aprataxin and PNK-like factor isoform X2\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"105676740 PNKP; uncharacterized protein F21D5.5\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"105667555 Dsp1; high mobility group protein DSP1 isoform X1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"105676389 Parp1; poly [ADP-ribose] polymerase\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"105676533 Xpc; DNA repair protein complementing XP-C cells\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"105678184 UV excision repair protein RAD23 homolog A\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"105674184 Roc1a; RING-box protein 1A isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"105679571 Cul4; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"105679961 pic; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"105677199 Polr2A; DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"105674410 Polr2B; DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"105668242 Polr2C; DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"105670625 Polr2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"105671352 Polr2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"105668409 Polr2G; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"105675987 Polr2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"105678699 Polr2I; DNA-directed RNA polymerase II subunit RPB9 isoform X1\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"105674240 Polr2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"105679955 DNA-directed RNA polymerase II subunit RPB11\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"105679956 DNA-directed RNA polymerase II subunit RPB11-like isoform X1\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"105678155 Polr2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"105674184 Roc1a; RING-box protein 1A isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"105679571 Cul4; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"105679961 pic; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"105667559 DNA excision repair protein ERCC-6\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"105676677 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"105667401 hay; general transcription and DNA repair factor IIH helicase\/translocase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"105670228 Xpd; general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"105680144 Tfb1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"105667375 Ssl1; general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"105675741 Tfb4; general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"105672127 mrn; general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"105671666 Tfb5; general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"105668344 Cdk7; cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"105676356 CycH; cyclin-H\tK06634 CCNH; cyclin H"
					},
					{
						"name":"105668530 Mat1; CDK-activating kinase assembly factor MAT1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"105677186 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"136999937 replication protein A 32 kDa subunit-like\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"105667952 Xpac; DNA repair protein complementing XP-A cells homolog\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"105673378 Ercc1; DNA excision repair protein ERCC-1 isoform X1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"105670061 mei-9; DNA repair endonuclease XPF\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"105674533 mus201; DNA excision repair protein ERCC-5 isoform X2\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"105673270 DNAlig1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"105670352 Mms19; MMS19 nucleotide excision repair protein isoform X1\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"105668560 Ciao1; probable cytosolic iron-sulfur protein assembly protein Ciao1 isoform X1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"105670929 galla-1; MIP18 family protein galla-1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"105676725 galla-2; MIP18 family protein galla-2\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"105674135 Cul3; cullin-3\tK03869 CUL3; cullin 3"
					},
					{
						"name":"105670227 Cul5; cullin-5 isoform X2\tK10612 CUL5; cullin 5"
					},
					{
						"name":"105672322 EloC; elongin-C isoform X1\tK03872 ELOC; elongin-C"
					},
					{
						"name":"105674966 EloB; elongin-B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"105676824 EloA; transcription elongation factor B polypeptide 3 isoform X1\tK15076 ELOA; elongin-A"
					},
					{
						"name":"105674459 lig; protein lingerer isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"105673743 spel1; DNA mismatch repair protein Msh2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"105677715 Msh6; probable DNA mismatch repair protein Msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"105675361 Mlh1; DNA mismatch repair protein Mlh1 isoform X1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"105677493 Pms2; mismatch repair endonuclease PMS2\tK10858 PMS2; DNA mismatch repair protein PMS2"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"105668277 PolD1; DNA polymerase delta catalytic subunit isoform X1\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"105675392 DNA polymerase delta subunit 2-like\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"105679854 DNA polymerase delta subunit 2-like\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"105669168 DNA polymerase delta subunit 3-like\tK03504 POLD3; DNA polymerase delta subunit 3"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"105677186 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"136999937 replication protein A 32 kDa subunit-like\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"105677664 Gnf1; replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"105668804 RfC4; replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"105676730 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"105669423 RfC38; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"105671026 RfC3; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"105676428 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105667303 tos; exonuclease 1 isoform X2\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"105667555 Dsp1; high mobility group protein DSP1 isoform X1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"105673270 DNAlig1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"105671953 mre11; double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105673374 nibrin-like\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"105679600 breast cancer type 1 susceptibility protein homolog isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"105671301 BRCA1-associated RING domain protein 1-like isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"105679600 breast cancer type 1 susceptibility protein homolog isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"105667597 BRISC and BRCA1-A complex member 1-like\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"105677778 BRISC and BRCA1-A complex member 2-like\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"105673972 Rpn11; lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"105679600 breast cancer type 1 susceptibility protein homolog isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"105670837 Fanconi anemia group J protein homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"105670670 mus101; DNA topoisomerase 2-binding protein 1 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"105679600 breast cancer type 1 susceptibility protein homolog isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"105678593 uncharacterized protein\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"105671953 mre11; double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105673374 nibrin-like\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"105679600 breast cancer type 1 susceptibility protein homolog isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"105673491 spn-A; DNA repair protein RAD51 homolog A\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"105673491 spn-A; DNA repair protein RAD51 homolog A\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"105671280 Xrcc2; DNA repair protein XRCC2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"105671832 DNA repair protein XRCC3-like\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"105673837 DNA repair protein RAD52 homolog isoform X1\tK10873 RAD52; DNA repair and recombination protein RAD52"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"105672577 okr; DNA repair and recombination protein RAD54-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"105676679 uncharacterized protein isoform X1\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"105675780 DNA repair and recombination protein RAD54B-like\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"105667504 ATP-dependent DNA helicase Q1-like\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"105668317 Blm; recQ-like DNA helicase Blm\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105678214 RecQ4; ATP-dependent DNA helicase Q4\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"105668317 Blm; recQ-like DNA helicase Blm\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105667342 Top3beta; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105674762 Top3alpha; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105673063 recQ-mediated genome instability protein 1-like isoform X1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"105677186 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"136999937 replication protein A 32 kDa subunit-like\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"105673124 Pp4-19C; serine\/threonine-protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105675445 serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"105678582 serine\/threonine-protein phosphatase 4 regulatory subunit 2\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"105676538 flfl; serine\/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"105673933 serine\/threonine-protein phosphatase 4 regulatory subunit 4-like isoform X1\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"105676393 SMC5; structural maintenance of chromosomes protein 5\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"105678826 SMC6; structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"105679120 Nse1; non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"105673057 E3 SUMO-protein ligase NSE2-like\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"105675792 MAGE; non-structural maintenance of chromosomes element 3 homolog\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"105668001 Nse4; EP300-interacting inhibitor of differentiation 3\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"105672520 mms4; crossover junction endonuclease EME1 isoform X1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"105672596 Exd2; exonuclease 3'-5' domain-containing protein 2\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"105677773 mus81; crossover junction endonuclease MUS81 isoform X2\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"105677760 Sem1; 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"105673580 slx1; structure-specific endonuclease subunit slx1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"105673313 Gen; flap endonuclease GEN\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"105667443 spatacsin\tK19026 SPG11; spatacsin"
					},
					{
						"name":"105674602 Sptz; uncharacterized protein Sptz\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"105667312 MRG15; mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"105669590 fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"105676821 uncharacterized protein\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"105672971 uncharacterized protein isoform X1\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"105675245 zinc finger SWIM domain-containing protein 7-like\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"105674270 BRCA2-interacting transcriptional repressor EMSY\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"105667766 heat shock factor 2-binding protein-like\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"105671283 protein MMS22-like isoform X2\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"105667697 tonsoku-like protein\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"105671138 biorientation of chromosomes in cell division protein 1-like 1\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"105676911 uncharacterized protein PF3D7_1120600-like\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"105671518 DNA helicase MCM8 isoform X1\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"105675928 DNA helicase MCM9-like isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"105670383 heterogeneous nuclear ribonucleoprotein U isoform X1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"105673809 WRNexo; 3'-5' exonuclease isoform X2\tK22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"105668659 Irbp; X-ray repair cross-complementing protein 6 isoform X1\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"105672624 Ku80; X-ray repair cross-complementing protein 5\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"105673241 DNA-dependent protein kinase catalytic subunit-like\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"105671953 mre11; double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"105677399 DNA repair protein XRCC4-like\tK10886 XRCC4; DNA-repair protein XRCC4"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"105674311 DNA polymerase beta-like\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"105672859 aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"105672044 aprataxin and PNK-like factor isoform X2\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"105671476 Snm1; protein artemis isoform X1\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"105668065 E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"105673742 Fancm; DEAD-box ATP-dependent DNA helicase Fancm\tK10896 FANCM; fanconi anemia group M protein"
					}
					]
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"105668317 Blm; recQ-like DNA helicase Blm\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105667342 Top3beta; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105674762 Top3alpha; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105673063 recQ-mediated genome instability protein 1-like isoform X1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"105679633 FANCI; Fanconi anemia group I protein\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"105679600 breast cancer type 1 susceptibility protein homolog isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"105670837 Fanconi anemia group J protein homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"105671358 fanconi-associated nuclease 1-like\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"105673491 spn-A; DNA repair protein RAD51 homolog A\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"105678972 Usp1; ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"105670340 WD repeat-containing protein 48\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"105668147 PpV; serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105672049 fmt; serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"105671220 serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like isoform X1\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"105675751 E3 ubiquitin-protein ligase rnf8-A-like\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"105669552 uncharacterized protein\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"105673906 HERC2; E3 ubiquitin-protein ligase HERC2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"105670982 WDR79; telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"105669673 gastrulation defective protein 1 homolog\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"105678046 abasic site processing protein HMCES\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"105668099 PolH; DNA polymerase eta\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"105679976 PolI; DNA polymerase iota\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"105678165 Rev1; DNA repair protein Rev1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"105678889 PolZ1; DNA polymerase zeta catalytic subunit isoform X1\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"105677767 Ubc6; ubiquitin-conjugating enzyme E2-17 kDa isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"105668230 E3 ubiquitin-protein ligase RAD18-like isoform X1\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"105677519 Uev1A; ubiquitin-conjugating enzyme E2 variant 2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105676160 ben; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"105676428 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"105667882 mh; DNA-dependent metalloprotease dvc-1\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"105667345 germ cell nuclear acidic protein isoform X1\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"105671331 Rad9; cell cycle checkpoint control protein RAD9A\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"105668532 checkpoint protein HUS1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"105668879 checkpoint protein HUS1-like\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"105675244 Rad1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"105673180 Rad17; cell cycle checkpoint protein RAD17\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"105668804 RfC4; replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"105676730 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"105669423 RfC38; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"105671026 RfC3; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"105675244 Rad1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"105672163 protein timeless homolog isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"105676086 protein TIPIN homolog\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"105674528 claspin\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"105677575 Tti1; TELO2-interacting protein 1 homolog\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"105671748 TELO2-interacting protein 2\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"105678303 large proline-rich protein BAG6 isoform X1\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"105679890 ubiquitin-like protein 4A\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"105676885 Golgi to ER traffic protein 4 homolog\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"105678294 IntS3; integrator complex subunit 3 isoform X1\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"105672727 SOSS complex subunit B homolog isoform X1\tK28889 NABP; SOSS complex subunit B"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"105676899 mei-41; serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"105672391 tefu; serine-protein kinase ATM isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"105679793 grp; serine\/threonine-protein kinase grp\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"105668387 serine\/threonine-protein kinase Chk2\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"105674910 M-phase inducer phosphatase-like isoform X1\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"105669539 14-3-3zeta; 14-3-3 protein zeta isoform X1\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"105679080 14-3-3epsilon; 14-3-3 protein epsilon\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105671570 wee1-like protein kinase 2 isoform X1\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"105668944 per; period circadian protein isoform X1\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"105680086 serine-rich adhesin for platelets\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"105671687 Fim; plastin-2 isoform X1\tK17336 PLS3; plastin-3"
				},
				{
					"name":"105667592 hd; protein downstream neighbor of son homolog isoform X1\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"105671673 Kank; KN motif and ankyrin repeat domain-containing protein 2 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"105673553 Vps4; vacuolar protein sorting-associated protein 4\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"105673259 abscission\/NoCut checkpoint regulator isoform X1\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"105675805 bc10; apoptosis inducing factor BLCAP\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"105668484 PolQ; DNA polymerase theta isoform X1\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"105671547 myb-binding protein 1A\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"105672636 DNA-directed primase\/polymerase protein-like\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"105672024 uncharacterized protein isoform X1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"105668463 mus301; helicase POLQ-like\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"105670659 Prp19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"105677612 Cdc5; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"105679776 BCAS2; pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"105678857 Tango4; pleiotropic regulator 1 isoform X1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"105670594 8-oxo-dGDP phosphatase NUDT18\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"105670072 ribonucleoside-diphosphate reductase large subunit-like\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"105670998 ribonucleoside-diphosphate reductase large subunit-like\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"105679058 RnrL; ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"105667883 RnrS; ribonucleoside-diphosphate reductase subunit M2 B isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair"
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"105678652 Smug; single-strand selective monofunctional uracil DNA glycosylase\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"105670507 DNA-3-methyladenine glycosylase-like isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"105674101 Nthl1; endonuclease III-like protein 1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"105668756 mtSSB; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"105668756 mtSSB; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}