{
	"name":"lli03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"uc509_0822 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"uc509_0371 era; GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"uc509_1533 obgE; GTPase, Obg\/CgtA family\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"uc509_0776 nusA; Transcription antitermination factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"uc509_0688 nusB; transcription termination protein nusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"uc509_2085 nusG; transcription antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"uc509_2211 ribosomal small subunit pseudouridine synthase A\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"uc509_0684 ksgA; dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"uc509_1850 sunL; 16S rRNA m(5)C 967 methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"uc509_1406 rsmC; 16S rRNA m(2)G 1207 methyltransferase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"uc509_2140 Methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"uc509_0084 16S ribosomal RNA methyltransferase RsmE\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"uc509_1357 gidB; 16S rRNA methyltransferase GidB\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"uc509_0897 mraW; S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"uc509_0426 Tetrapyrrole (Corrin\/Porphyrin) methylase family protein\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"uc509_0891 rRNA methylase\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"uc509_1342 23S rRNA m(1)G 745 methyltransferase\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"uc509_1958 rrmA; 23S rRNA m(1)G 745 methyltransferase\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"uc509_1832 trmH; 23S rRNA Gm2251 methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"uc509_2114 Ribosomal RNA large subunit methyltransferase H\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"uc509_0257 SAM-dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"uc509_0176 ribosomal RNA large subunit methyltransferase N\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"uc509_0891 rRNA methylase\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"uc509_1198 23S rRNA m(5)U 1939 methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"uc509_1289 rluB; Ribosomal large subunit pseudouridine synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"uc509_0384 rluE; Ribosomal large subunit pseudouridine synthase D, RluA family\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"uc509_1050 rluD; ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"uc509_2092 rluE; ribosomal large subunit pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"uc509_1376 rluE; ribosomal large subunit pseudouridine synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"uc509_0302 Ribosomal-protein-S18-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"uc509_0303 rimI2; ribosomal-protein-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"uc509_1520 rimM; 16S rRNA-processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"uc509_0083 prmA; ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"uc509_0822 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"uc509_0125 Holliday junction resolvase-like protein\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			},
			{
				"name":"uc509_1808 rnc; ribonuclease III\tK11145 mrnC; mini-ribonuclease III [EC:3.1.26.-]"
			},
			{
				"name":"uc509_0683 Ribonuclease M5\tK05985 rnmV; ribonuclease M5 [EC:3.1.26.8]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"uc509_0369 rheA; ATP-dependent RNA helicase, DEAD\/DEAH box family\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"uc509_0443 rheA; ATP-dependent RNA helicase, DEAD\/DEAH box family\tK18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"uc509_0371 era; GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"uc509_1904 ribosome-associated GTPase\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"uc509_0763 engA; GTP-binding protein EngA\tK03977 engA; GTPase"
			},
			{
				"name":"uc509_1533 obgE; GTPase, Obg\/CgtA family\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"uc509_1310 rbgA; ribosomal biogenesis GTPase\tK14540 rbgA; ribosome biogenesis GTPase A"
			},
			{
				"name":"uc509_0225 hflX; GTP-binding protein hflX\tK03665 hflX; GTPase"
			},
			{
				"name":"uc509_0223 GTP-binding protein YqeH\tK06948 yqeH; 30S ribosome assembly GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"uc509_0601 RNA-binding protein, Sua5\/YciO\/YrdC\/YwlC family\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"uc509_0086 relA; GTP pyrophosphokinase \/ Guanosine-3,5-bis(Diphosphate) 3-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"uc509_0781 rbfA; ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"uc509_0775 Hypothetical protein\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"uc509_1940 hypothetical protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"uc509_0230 hypothetical protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"uc509_1086 putative metalloprotease\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"uc509_0226 RNA binding protein, CRS1\/YhbY family\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"uc509_0651 yfiA; putative sigma 54 modulation protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"uc509_0007 GTP-dependent nucleic acid-binding protein, probable translation factor\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"uc509_1541 hypothetical protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}
