{
	"name":"lpo01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"LPO_0925 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"LPO_2889 murB; UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"LPO_2890 murC; UDP-N-acetylmuramate:L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"LPO_2892 murD; UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"LPO_1001 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"LPO_2888 ddlA; D-alanine--D-alanine ligase A\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"LPO_0819 alr; alanine racemase 1, PLP-binding, biosynthetic\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"LPO_2385 murI; Glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"LPO_p0021 Muramoyltetrapeptide carboxypeptidase\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"LPO_2893 mraY; phospho-N-acetylmuramoyl-pentapeptide transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"LPO_0886 murG; UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase"
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"LPO_2913 mviN; Virulence factor mviN homolog\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"LPO_1009 mrcA; fused penicillin-binding protein 1a: murein transglycosylase; murein transpeptidase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"LPO_1699 Penicillin-binding protein 1C precursor\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"LPO_1365 mrdA; transpeptidase involved in peptidoglycan synthesis (penicillin-binding protein 2)\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"LPO_1000 ftsI; transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3)\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"LPO_1522 dacC; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6a)\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"LPO_2863 putative Serine-type D-Ala-D-Ala carboxypeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"LPO_2891 ftsW; integral membrane protein involved in stabilizing FstZ ring during cell division\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"LPO_1364 rodA; cell wall shape-determining protein\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase",
			"children":[
			{
				"name":"LPO_1615 putative ErfK\/YbiS\/YcfS\/YnhG family protein precursor\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"LPO_1528 lssA; Legionella secretion system protein A\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"LPO_2639 D-alanyl-D-alanine dipeptidase\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
			},
			{
				"name":"LPO_2852 vanX; D-alanyl-D-alanine dipeptidase\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
			}
			]
		},
		{
			"name":"Endopeptidase"
		},
		{
			"name":"Sortase"
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"LPO_0743 putative Soluble lytic murein transglycosylase\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"LPO_2091 mltA; Membrane-bound lytic murein transglycosylase family protein\tK08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29]"
			},
			{
				"name":"LPO_1934 Membrane-bound lytic transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"LPO_3240 mltB; lytic murein transglycosylase\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"LPO_1126 membrane bound lytic murein transglycosylase D\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
			},
			{
				"name":"LPO_1278 mltD; membrane bound lytic murein transglycosylase D\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
			},
			{
				"name":"LPO_1394 yceG; putative conserved membrane associated protein\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			},
			{
				"name":"LPO_1521 rlpA; rare lipoprotein A\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"LPO_2763 conserved protein of unknown function\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"LPO_2980 amiB; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein"
		}
		]
	}
	]
}