{
	"name":"lss04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"NCTC12082_00548 htpG; Class III heat-shock protein HtpG(molecular chaperone)\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"NCTC12082_02652 fda; fructose-bisphosphate aldolase, class I\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
			},
			{
				"name":"NCTC12082_01461 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"NCTC12082_02189 gap; glyceraldehyde 3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"NCTC12082_02188 pgk; phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"NCTC12082_02187 pykA; pyruvate kinase II\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"NCTC12082_01951 ahpC; peroxiredoxin (alkyl hydroperoxide reductase subunit C)\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"NCTC12082_02914 htpB; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC12082_02756 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"NCTC12082_02029 gpi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"NCTC12082_00849 guaB; inosine 5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"NCTC12082_01898 guaC; GMP reductase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"NCTC12082_02357 tufA_1; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC12082_02370 tufA_2; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC12082_01823 hinT; HIT family hydrolase\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells"
		},
		{
			"name":"Exosomal proteins of hepatic cells"
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"NCTC12082_00803 fadD; long-chain fatty-acid-CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"NCTC12082_02914 htpB; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC12082_00256 yfcY; beta-ketoacyl-CoA thiolase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"NCTC12082_00374 pcaF; thiolase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"NCTC12082_02859 paaJ; acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"NCTC12082_02521 ahcY; adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"NCTC12082_02760 sAM1; adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"NCTC12082_00407 adk; adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"NCTC12082_02486 argH; argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"NCTC12082_02487 argG; argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"NCTC12082_00058 NG,NG-dimethylarginine dimethylaminohydrolase\tK01482 DDAH; dimethylargininase [EC:3.5.3.18]"
			},
			{
				"name":"NCTC12082_02944 2-keto-4-pentenoate hydratase\/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)\tK01555 FAH; fumarylacetoacetase [EC:3.7.1.2]"
			},
			{
				"name":"NCTC12082_00410 glpK; glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"NCTC12082_00550 glnA_1; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"NCTC12082_01340 glnA_2; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"NCTC12082_02029 gpi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"NCTC12082_01022 hemB; porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"NCTC12082_00029 lly; 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"NCTC12082_01055 Pterin-4a-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"NCTC12082_02642 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"NCTC12082_00803 fadD; long-chain fatty-acid-CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"NCTC12082_00734 lpdA; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"NCTC12082_00952 etfA; electron transfer flavoprotein, alpha subuni\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"NCTC12082_00094 zwf; glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"NCTC12082_00849 guaB; inosine 5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"NCTC12082_01898 guaC; GMP reductase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"NCTC12082_02756 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"NCTC12082_02914 htpB; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC12082_02357 tufA_1; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC12082_02370 tufA_2; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"NCTC12082_02914 htpB; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC12082_02029 gpi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"NCTC12082_00094 zwf; glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"NCTC12082_02756 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"NCTC12082_01849 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"NCTC12082_02357 tufA_1; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC12082_02370 tufA_2; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"NCTC12082_02914 htpB; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC12082_00094 zwf; glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"NCTC12082_01849 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"NCTC12082_01849 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}