{ "name":"mdt03019", "children":[ { "name":"Eukaryotic type", "children":[ { "name":"mRNA processing factors", "children":[ { "name":"5' end processing", "children":[ { "name":"Capping factors", "children":[ { "name":"132239811 RNMT; (RefSeq) mRNA cap guanine-N7 methyltransferase isoform X1\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]" }, { "name":"132237076 RNGTT; (RefSeq) mRNA-capping enzyme isoform X1\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]" }, { "name":"132240057 LOW QUALITY PROTEIN: mRNA-capping enzyme-like\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]" }, { "name":"132233566 CDK7; (RefSeq) cyclin-dependent kinase 7 isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"132228506 UBAC2; (RefSeq) LOW QUALITY PROTEIN: ubiquitin-associated domain-containing protein 2\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]" }, { "name":"132237380 CMTR1; (RefSeq) cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]" }, { "name":"132217379 CMTR2; (RefSeq) cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]" }, { "name":"132222812 RAMAC; (RefSeq) RNA guanine-N7 methyltransferase activating subunit\tK18708 FAM103A1; RNMT-activating mini protein" } ] }, { "name":"Cap binding complex", "children":[ { "name":"132212172 NCBP1; (RefSeq) nuclear cap-binding protein subunit 1 isoform X1\tK12882 NCBP1; nuclear cap-binding protein subunit 1" }, { "name":"132224368 NCBP2L; (RefSeq) LOW QUALITY PROTEIN: nuclear cap-binding protein subunit 2-like\tK12883 NCBP2; nuclear cap-binding protein subunit 2" }, { "name":"132230272 NCBP2; (RefSeq) nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2" } ] } ] }, { "name":"3' end processing", "children":[ { "name":"Pre-mRNA cleavage factor Im (CFIm)", "children":[ { "name":"132212013 cleavage and polyadenylation specificity factor subunit 5-like\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5" }, { "name":"132217571 NUDT21; (RefSeq) cleavage and polyadenylation specificity factor subunit 5 isoform X1\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5" }, { "name":"132223709 cleavage and polyadenylation specificity factor subunit 5-like\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5" }, { "name":"132223710 cleavage and polyadenylation specificity factor subunit 5-like\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5" }, { "name":"132240727 cleavage and polyadenylation specificity factor subunit 5-like\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5" }, { "name":"132227907 CPSF6; (RefSeq) cleavage and polyadenylation specificity factor subunit 6 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" }, { "name":"132240784 LOW QUALITY PROTEIN: cleavage and polyadenylation specificity factor subunit 6-like\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" }, { "name":"132241571 CPSF7; (RefSeq) cleavage and polyadenylation specificity factor subunit 7 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" }, { "name":"132242072 cleavage and polyadenylation specificity factor subunit 6-like\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" } ] }, { "name":"Pre-mRNA cleavage factor IIm (CFIIm)", "children":[ { "name":"132229260 polyribonucleotide 5'-hydroxyl-kinase Clp1-like isoform X1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]" }, { "name":"132232338 polyribonucleotide 5'-hydroxyl-kinase Clp1-like\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]" }, { "name":"132241144 CLP1; (RefSeq) polyribonucleotide 5'-hydroxyl-kinase Clp1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]" }, { "name":"132218505 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132218611 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132219352 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132219362 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132219367 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132219371 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132219378 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132219382 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132219386 LOW QUALITY PROTEIN: pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132238772 pre-mRNA cleavage complex 2 protein Pcf11-like\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" }, { "name":"132240725 PCF11; (RefSeq) pre-mRNA cleavage complex 2 protein Pcf11 isoform X1\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" } ] }, { "name":"Cleavage and polyadenylation specificity factor (CPSF) complex", "children":[ { "name":"132219859 CPSF1; (RefSeq) cleavage and polyadenylation specificity factor subunit 1 isoform X1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1" }, { "name":"132230418 CPSF2; (RefSeq) cleavage and polyadenylation specificity factor subunit 2 isoform X1\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2" }, { "name":"132213657 CPSF3; (RefSeq) cleavage and polyadenylation specificity factor subunit 3 isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"132219045 CPSF4L; (RefSeq) putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X1\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4" }, { "name":"132232308 CPSF4; (RefSeq) cleavage and polyadenylation specificity factor subunit 4 isoform X1\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4" }, { "name":"132219074 FIP1L1; (RefSeq) pre-mRNA 3'-end-processing factor FIP1 isoform X1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1" }, { "name":"132238742 WDR33; (RefSeq) pre-mRNA 3' end processing protein WDR33 isoform X1\tK15542 PFS2; polyadenylation factor subunit 2" }, { "name":"132215342 WDR82; (RefSeq) WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2" }, { "name":"132212742 serine\/threonine-protein phosphatase PP1-gamma catalytic subunit A-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"132213506 PPP1CB; (RefSeq) serine\/threonine-protein phosphatase PP1-beta catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"132221703 PPP1CC; (RefSeq) serine\/threonine-protein phosphatase PP1-gamma catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"132241338 PPP1CA; (RefSeq) serine\/threonine-protein phosphatase PP1-alpha catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"132223512 RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]" }, { "name":"132223513 RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]" }, { "name":"132223514 RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]" }, { "name":"132231794 SSU72; (RefSeq) RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]" } ] }, { "name":"Cleavage stimulation factor (CSTF) complex", "children":[ { "name":"132230887 cleavage stimulation factor subunit 1-like\tK14406 CSTF1; cleavage stimulation factor subunit 1" }, { "name":"132239221 CSTF1; (RefSeq) cleavage stimulation factor subunit 1 isoform X1\tK14406 CSTF1; cleavage stimulation factor subunit 1" }, { "name":"132239919 cleavage stimulation factor subunit 1-like\tK14406 CSTF1; cleavage stimulation factor subunit 1" }, { "name":"132214957 CSTF2T; (RefSeq) cleavage stimulation factor subunit 2 tau variant\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"132230938 cleavage stimulation factor subunit 2 tau variant-like\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"132241289 CSTF3; (RefSeq) cleavage stimulation factor subunit 3 isoform X1\tK14408 CSTF3; cleavage stimulation factor subunit 3" }, { "name":"132216717 SYMPK; (RefSeq) symplekin isoform X1\tK06100 SYMPK; symplekin" } ] }, { "name":"U7-dependent histone pre-mRNA processing factors", "children":[ { "name":"132239451 SNRPB; (RefSeq) small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"132222282 SNRPD3; (RefSeq) small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"132214578 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"132221296 SNRPE; (RefSeq) small nuclear ribonucleoprotein E isoform X1\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"132232450 small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"132240835 small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"132224806 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"132224966 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"132227154 SNRPF; (RefSeq) small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"132213244 SNRPG; (RefSeq) small nuclear ribonucleoprotein G isoform X1\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132213287 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132213886 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132214548 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132214997 small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132215127 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132222131 small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132226165 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"132231307 LSM10; (RefSeq) U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10" }, { "name":"132235908 LSM11; (RefSeq) U7 snRNA-associated Sm-like protein LSm11 isoform X1\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11" }, { "name":"132230418 CPSF2; (RefSeq) cleavage and polyadenylation specificity factor subunit 2 isoform X1\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2" }, { "name":"132213657 CPSF3; (RefSeq) cleavage and polyadenylation specificity factor subunit 3 isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"132214957 CSTF2T; (RefSeq) cleavage stimulation factor subunit 2 tau variant\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"132230938 cleavage stimulation factor subunit 2 tau variant-like\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"132216717 SYMPK; (RefSeq) symplekin isoform X1\tK06100 SYMPK; symplekin" }, { "name":"132222540 SLBP; (RefSeq) histone RNA hairpin-binding protein isoform X1\tK18710 SLBP; histone RNA hairpin-binding protein" }, { "name":"132237078 CASP8AP2; (RefSeq) CASP8-associated protein 2 isoform X1\tK25593 CASP8AP2; CASP8-associated protein 2" } ] }, { "name":"DRB sensitivity inducing factor (DSIF) complex", "children":[ { "name":"132218412 SUPT4H1; (RefSeq) transcription elongation factor SPT4 isoform X1\tK15171 SUPT4H1; transcription elongation factor SPT4" }, { "name":"132228376 transcription elongation factor SPT4-A-like\tK15171 SUPT4H1; transcription elongation factor SPT4" }, { "name":"132234062 transcription elongation factor SPT4-A-like\tK15171 SUPT4H1; transcription elongation factor SPT4" }, { "name":"132234065 transcription elongation factor SPT4-A-like\tK15171 SUPT4H1; transcription elongation factor SPT4" }, { "name":"132216897 SUPT5H; (RefSeq) transcription elongation factor SPT5 isoform X1\tK15172 SUPT5H; transcription elongation factor SPT5" }, { "name":"132229597 LOW QUALITY PROTEIN: transcription elongation factor SPT5-like\tK15172 SUPT5H; transcription elongation factor SPT5" } ] }, { "name":"N6-methyltransferase complex", "children":[ { "name":"132239934 METTL3; (RefSeq) N6-adenosine-methyltransferase catalytic subunit\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]" }, { "name":"132234557 METTL14; (RefSeq) LOW QUALITY PROTEIN: N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit" }, { "name":"132239752 METTL4; (RefSeq) N(6)-adenine-specific methyltransferase METTL4 isoform X1\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]" }, { "name":"132218231 METTL16; (RefSeq) RNA N6-adenosine-methyltransferase METTL16\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]" }, { "name":"132236732 WTAP; (RefSeq) pre-mRNA-splicing regulator WTAP isoform X1\tK22824 WTAP; pre-mRNA-splicing regulator WTAP" }, { "name":"132219720 VIRMA; (RefSeq) protein virilizer homolog isoform X1\tK22910 VIRMA; protein virilizer" }, { "name":"132215811 RBM15B; (RefSeq) putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15" }, { "name":"132220593 RBM15; (RefSeq) RNA-binding protein 15 isoform X1\tK13190 RBM15; RNA-binding protein 15" }, { "name":"132228303 ZC3H13; (RefSeq) zinc finger CCCH domain-containing protein 13 isoform X1\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13" }, { "name":"132211124 CBLL1; (RefSeq) E3 ubiquitin-protein ligase Hakai isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]" } ] }, { "name":"Poly(A) addition factors", "children":[ { "name":"132213332 PAPOLG; (RefSeq) poly(A) polymerase gamma isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"132229434 PAPOLA; (RefSeq) poly(A) polymerase alpha isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"132236036 PAPOLB; (RefSeq) poly(A) polymerase beta\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"132233483 TENT2; (RefSeq) poly(A) RNA polymerase GLD2 isoform X1\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]" }, { "name":"132241542 TUT1; (RefSeq) speckle targeted PIP5K1A-regulated poly(A) polymerase isoform X1\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]" } ] }, { "name":"Negative regulators of mRNA 3' end processing", "children":[ { "name":"132238198 BARD1; (RefSeq) BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"132228465 RBM26; (RefSeq) RNA-binding protein 26 isoform X1\tK13192 RBM26; RNA-binding protein 26" }, { "name":"132217581 FTO; (RefSeq) alpha-ketoglutarate-dependent dioxygenase FTO isoform X1\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]" }, { "name":"132217920 ALKBH5; (RefSeq) RNA demethylase ALKBH5 isoform X1\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]" }, { "name":"132231693 TARDBP; (RefSeq) TAR DNA-binding protein 43\tK23600 TARDBP; TAR DNA-binding protein 43" } ] } ] }, { "name":"Other processing factors", "children":[ { "name":"132218522 DHX40; (RefSeq) probable ATP-dependent RNA helicase DHX40 isoform X1\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]" }, { "name":"132215501 KIN; (RefSeq) DNA\/RNA-binding protein KIN17 isoform X1\tK13102 KIN; DNA\/RNA-binding protein KIN17" }, { "name":"132238541 METTL8; (RefSeq) tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial isoform X1\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]" }, { "name":"132233063 METTL22; (RefSeq) methyltransferase-like protein 22 isoform X1\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]" }, { "name":"132227321 LOW QUALITY PROTEIN: terminal nucleotidyltransferase 5B-like\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"132231468 TENT5B; (RefSeq) terminal nucleotidyltransferase 5B isoform X1\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"132237126 TENT5A; (RefSeq) terminal nucleotidyltransferase 5A isoform X1\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"132220441 TENT5C; (RefSeq) terminal nucleotidyltransferase 5C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]" }, { "name":"132213867 LOW QUALITY PROTEIN: terminal nucleotidyltransferase 5D-like\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]" }, { "name":"132224402 TENT5D; (RefSeq) terminal nucleotidyltransferase 5D\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]" }, { "name":"132230692 ZC3H14; (RefSeq) zinc finger CCCH domain-containing protein 14 isoform X1\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14" }, { "name":"132233246 SRRT; (RefSeq) serrate RNA effector molecule homolog isoform X1\tK27103 SRRT; serrate RNA effector molecule" } ] } ] }, { "name":"mRNA surveillance and transport factors", "children":[ { "name":"Transport factors", "children":[ { "name":"EJC complex", "children":[ { "name":"132220963 RBM8A; (RefSeq) RNA-binding protein 8A isoform X1\tK12876 RBM8A; RNA-binding protein 8A" }, { "name":"132227283 MAGOHB; (RefSeq) protein mago nashi homolog 2 isoform X1\tK12877 MAGOH; protein mago nashi" }, { "name":"132231058 MAGOH; (RefSeq) protein mago nashi homolog\tK12877 MAGOH; protein mago nashi" }, { "name":"132239732 protein mago nashi homolog\tK12877 MAGOH; protein mago nashi" }, { "name":"132219218 ALYREF; (RefSeq) THO complex subunit 4\tK12881 THOC4; THO complex subunit 4" }, { "name":"132225614 LOW QUALITY PROTEIN: THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132225616 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226070 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226071 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226072 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226073 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226074 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226075 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226076 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226077 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226079 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132232518 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234061 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234436 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234437 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234438 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234439 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234440 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234445 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234447 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237653 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237654 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237655 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237656 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237657 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237658 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237659 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237660 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237661 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237662 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237663 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237664 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237665 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237666 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237667 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237668 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237669 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237671 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237672 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237673 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237674 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237675 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237676 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237518 DDX39B; (RefSeq) spliceosome RNA helicase DDX39B\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]" }, { "name":"132240179 LOW QUALITY PROTEIN: spliceosome RNA helicase DDX39B-like\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]" }, { "name":"132219180 EIF4A3; (RefSeq) eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"132227246 eukaryotic initiation factor 4A-III-like\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"132215458 CCDC174; (RefSeq) coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174" }, { "name":"132218966 CASC3; (RefSeq) protein CASC3 isoform X1\tK14323 CASC3; protein CASC3" }, { "name":"132219629 histone deacetylase complex subunit SAP18-like\tK14324 SAP18; histone deacetylase complex subunit SAP18" }, { "name":"132228210 SAP18; (RefSeq) histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18" }, { "name":"132232343 histone deacetylase complex subunit SAP18-like\tK14324 SAP18; histone deacetylase complex subunit SAP18" }, { "name":"132213229 PNN; (RefSeq) pinin isoform X1\tK13114 PNN; pinin" }, { "name":"132240537 ACIN1; (RefSeq) apoptotic chromatin condensation inducer in the nucleus isoform X1\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus" }, { "name":"132232946 RNPS1; (RefSeq) RNA-binding protein with serine-rich domain 1 isoform X1\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1" }, { "name":"132231521 SRRM1; (RefSeq) serine\/arginine repetitive matrix protein 1 isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1" } ] }, { "name":"TREX complex", "children":[ { "name":"132222196 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232520 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232523 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232524 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232525 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232526 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232527 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232528 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232529 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232530 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232531 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232532 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232533 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232534 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232535 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232536 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232537 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232538 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132232539 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132236636 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132236638 LOW QUALITY PROTEIN: THO complex subunit 1-like\tK12878 THOC1; THO complex subunit 1" }, { "name":"132239738 THOC1; (RefSeq) THO complex subunit 1\tK12878 THOC1; THO complex subunit 1" }, { "name":"132216193 THO complex subunit 2-like\tK12879 THOC2; THO complex subunit 2" }, { "name":"132224154 THOC2; (RefSeq) THO complex subunit 2 isoform X1\tK12879 THOC2; THO complex subunit 2" }, { "name":"132230970 THO complex subunit 2-like\tK12879 THOC2; THO complex subunit 2" }, { "name":"132242682 LOW QUALITY PROTEIN: THO complex subunit 2-like\tK12879 THOC2; THO complex subunit 2" }, { "name":"132214762 THO complex subunit 3-like\tK12880 THOC3; THO complex subunit 3" }, { "name":"132235989 THOC3; (RefSeq) THO complex subunit 3\tK12880 THOC3; THO complex subunit 3" }, { "name":"132219218 ALYREF; (RefSeq) THO complex subunit 4\tK12881 THOC4; THO complex subunit 4" }, { "name":"132225614 LOW QUALITY PROTEIN: THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132225616 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226070 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226071 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226072 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226073 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226074 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226075 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226076 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226077 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132226079 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132232518 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234061 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234436 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234437 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234438 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234439 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234440 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234445 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132234447 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237653 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237654 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237655 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237656 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237657 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237658 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237659 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237660 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237661 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237662 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237663 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237664 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237665 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237666 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237667 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237668 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237669 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237671 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237672 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237673 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237674 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237675 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132237676 aly\/REF export factor 2-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"132216020 THO complex subunit 5 homolog\tK13174 THOC5; THO complex subunit 5" }, { "name":"132221655 THOC5; (RefSeq) THO complex subunit 5 homolog isoform X1\tK13174 THOC5; THO complex subunit 5" }, { "name":"132230622 LOW QUALITY PROTEIN: THO complex subunit 5 homolog\tK13174 THOC5; THO complex subunit 5" }, { "name":"132232978 THOC6; (RefSeq) THO complex subunit 6 homolog isoform X1\tK13175 THOC6; THO complex subunit 6" }, { "name":"132239985 THO complex subunit 6 homolog\tK13175 THOC6; THO complex subunit 6" }, { "name":"132213961 THO complex subunit 7 homolog\tK13176 THOC7; THO complex subunit 7" }, { "name":"132215232 THOC7; (RefSeq) THO complex subunit 7 homolog isoform X1\tK13176 THOC7; THO complex subunit 7" }, { "name":"132220700 CHTOP; (RefSeq) chromatin target of PRMT1 protein isoform X1\tK28424 CHTOP; chromatin target of PRMT1 protein" }, { "name":"132221386 chromatin target of PRMT1 protein-like isoform X1\tK28424 CHTOP; chromatin target of PRMT1 protein" }, { "name":"132229385 chromatin target of PRMT1 protein-like\tK28424 CHTOP; chromatin target of PRMT1 protein" } ] }, { "name":"TREX-2 complex", "children":[ { "name":"132228562 PCID2; (RefSeq) PCI domain-containing protein 2 isoform X1\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1" }, { "name":"132237962 LOW QUALITY PROTEIN: PCI domain-containing protein 2-like\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1" }, { "name":"132242705 LOW QUALITY PROTEIN: PCI domain-containing protein 2-like\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1" }, { "name":"132242967 SEM1; (RefSeq) 26S proteasome complex subunit SEM1 isoform X1\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"132219605 ENY2; (RefSeq) transcription and mRNA export factor ENY2 isoform X1\tK11368 ENY2; enhancer of yellow 2 transcription factor" }, { "name":"132229360 transcription and mRNA export factor ENY2-like\tK11368 ENY2; enhancer of yellow 2 transcription factor" }, { "name":"132216432 centrin-2\tK10840 CETN2; centrin-2" }, { "name":"132220045 centrin-2-like\tK10840 CETN2; centrin-2" }, { "name":"132223971 CETN2; (RefSeq) centrin-2\tK10840 CETN2; centrin-2" }, { "name":"132235903 centrin-2-like\tK10840 CETN2; centrin-2" }, { "name":"132233438 CETN3; (RefSeq) centrin-3 isoform X1\tK16466 CETN3; centrin-3" }, { "name":"132229986 MCM3AP; (RefSeq) germinal-center associated nuclear protein\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]" }, { "name":"132236113 LOW QUALITY PROTEIN: germinal-center associated nuclear protein-like\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]" } ] }, { "name":"Nuclear pore complex", "children":[ { "name":"132221284 TPR; (RefSeq) nucleoprotein TPR isoform X1\tK09291 TPR; nucleoprotein TPR" }, { "name":"132239213 RAE1; (RefSeq) mRNA export factor RAE1 isoform X1\tK14298 RAE1; mRNA export factor" }, { "name":"132215384 SEC13; (RefSeq) protein SEC13 homolog isoform X1\tK14004 SEC13; protein transport protein SEC13" }, { "name":"132211285 LOW QUALITY PROTEIN: nucleoporin Nup37-like\tK14302 NUP37; nuclear pore complex protein Nup37" }, { "name":"132227110 NUP37; (RefSeq) nucleoporin Nup37 isoform X1\tK14302 NUP37; nuclear pore complex protein Nup37" }, { "name":"132219087 NUP85; (RefSeq) nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85" }, { "name":"132236794 NUP43; (RefSeq) nucleoporin Nup43 isoform X1\tK14305 NUP43; nuclear pore complex protein Nup43" }, { "name":"132226887 NUP50; (RefSeq) nuclear pore complex protein Nup50 isoform X1\tK14295 NUP50; nuclear pore complex protein Nup50" }, { "name":"132217621 NUP54; (RefSeq) nucleoporin p54 isoform X1\tK14308 NUP54; nuclear pore complex protein Nup54" }, { "name":"132216199 NUP62; (RefSeq) nuclear pore glycoprotein p62\tK14306 NUP62; nuclear pore complex protein Nup62" }, { "name":"132218160 NUP88; (RefSeq) nuclear pore complex protein Nup88 isoform X1\tK14318 NUP88; nuclear pore complex protein Nup88" }, { "name":"132217557 NUP93; (RefSeq) nuclear pore complex protein Nup93 isoform X1\tK14309 NUP93; nuclear pore complex protein Nup93" }, { "name":"132240852 NUP98; (RefSeq) nuclear pore complex protein Nup98-Nup96 isoform X1\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96" }, { "name":"132227893 NUP107; (RefSeq) nuclear pore complex protein Nup107 isoform X1\tK14301 NUP107; nuclear pore complex protein Nup107" }, { "name":"132222448 NUP133; (RefSeq) nuclear pore complex protein Nup133 isoform X1\tK14300 NUP133; nuclear pore complex protein Nup133" }, { "name":"132212451 NUP188; (RefSeq) nucleoporin NUP188 isoform X1\tK14311 NUP188; nuclear pore complex protein Nup188" }, { "name":"132230753 NUP153; (RefSeq) nuclear pore complex protein Nup153 isoform X1\tK14296 NUP153; nuclear pore complex protein Nup153" }, { "name":"132233751 NUP155; (RefSeq) nuclear pore complex protein Nup155 isoform X1\tK14312 NUP155; nuclear pore complex protein Nup155" }, { "name":"132241174 NUP160; (RefSeq) nuclear pore complex protein Nup160\tK14303 NUP160; nuclear pore complex protein Nup160" }, { "name":"132211887 LOW QUALITY PROTEIN: nucleoporin NUP35-like\tK14313 NUP35; nuclear pore complex protein Nup53" }, { "name":"132238453 NUP35; (RefSeq) nucleoporin NUP35\tK14313 NUP35; nuclear pore complex protein Nup53" }, { "name":"132242793 NUP205; (RefSeq) nuclear pore complex protein Nup205 isoform X1\tK14310 NUP205; nuclear pore complex protein Nup205" }, { "name":"132220974 NUP210L; (RefSeq) nuclear pore membrane glycoprotein 210-like\tK14314 NUP210; nuclear pore complex protein Nup210" }, { "name":"132230609 NUP210; (RefSeq) nuclear pore membrane glycoprotein 210 isoform X1\tK14314 NUP210; nuclear pore complex protein Nup210" }, { "name":"132212493 NUP214; (RefSeq) nuclear pore complex protein Nup214 isoform X1\tK14317 NUP214; nuclear pore complex protein Nup214" }, { "name":"132211259 LOW QUALITY PROTEIN: nuclear envelope pore membrane protein POM 121C-like\tK14316 POM121; nuclear pore complex protein Nup121" }, { "name":"132220809 POM121L2; (RefSeq) POM121-like protein 2\tK14316 POM121; nuclear pore complex protein Nup121" }, { "name":"132233199 nuclear envelope pore membrane protein POM 121C-like isoform X1\tK14316 POM121; nuclear pore complex protein Nup121" }, { "name":"132228104 NUP58; (RefSeq) nucleoporin p58\/p45 isoform X1\tK14307 NUPL1; nucleoporin p58\/p45" }, { "name":"132243031 NUP42; (RefSeq) nucleoporin NUP42 isoform X1\tK14321 NUPL2; nucleoporin-like protein 2" }, { "name":"132231054 NDC1; (RefSeq) nucleoporin NDC1 isoform X1\tK14315 NDC1; nucleoporin NDC1" }, { "name":"132239808 SEH1L; (RefSeq) nucleoporin SEH1 isoform X1\tK14299 SEH1; nucleoporin SEH1" }, { "name":"132230615 E3 SUMO-protein ligase RanBP2-like isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]" }, { "name":"132230194 SENP2; (RefSeq) sentrin-specific protease 2 isoform X1\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]" }, { "name":"132227666 AAAS; (RefSeq) aladin isoform X1\tK14320 AAAS; aladin" }, { "name":"132233438 CETN3; (RefSeq) centrin-3 isoform X1\tK16466 CETN3; centrin-3" }, { "name":"132212440 GLE1; (RefSeq) mRNA export factor GLE1\tK18723 GLE1; nucleoporin GLE1" }, { "name":"132223495 nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223496 NXF3; (RefSeq) LOW QUALITY PROTEIN: nuclear RNA export factor 3\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223501 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223503 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223504 nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132236614 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132241517 NXF1; (RefSeq) nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor" }, { "name":"132220778 NTF2-related export protein 1\tK14285 NXT1_2; NTF2-related export protein 1\/2" }, { "name":"132225213 NXT2; (RefSeq) NTF2-related export protein 2 isoform X1\tK14285 NXT1_2; NTF2-related export protein 1\/2" }, { "name":"132239292 NXT1; (RefSeq) NTF2-related export protein 1\tK14285 NXT1_2; NTF2-related export protein 1\/2" }, { "name":"132242222 NTF2-related export protein 1-like\tK14285 NXT1_2; NTF2-related export protein 1\/2" } ] }, { "name":"Ran-mediated transport factors", "children":[ { "name":"132222305 RAN; (RefSeq) GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran" }, { "name":"132235154 ANP32A; (RefSeq) acidic leucine-rich nuclear phosphoprotein 32 family member A\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D" }, { "name":"132212183 ANP32B; (RefSeq) acidic leucine-rich nuclear phosphoprotein 32 family member B\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B" }, { "name":"132218066 TNFSF13; (RefSeq) tumor necrosis factor ligand superfamily member 13 isoform X1\tK05475 TNFSF13; tumor necrosis factor ligand superfamily member 13" }, { "name":"132234669 ELAVL1; (RefSeq) ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"132211855 ELAVL2; (RefSeq) ELAV-like protein 2 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"132231097 ELAVL4; (RefSeq) ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"132235032 ELAVL3; (RefSeq) ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"132235600 FAF2; (RefSeq) FAS-associated factor 2 isoform X1\tK18726 FAF2; FAS-associated factor 2" }, { "name":"132212105 VCP; (RefSeq) transitional endoplasmic reticulum ATPase isoform X1\tK13525 VCP; transitional endoplasmic reticulum ATPase" }, { "name":"132232614 protein N-lysine methyltransferase METTL21D-like isoform X1\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]" }, { "name":"132235072 VCPKMT; (RefSeq) protein N-lysine methyltransferase METTL21D isoform X1\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]" }, { "name":"132234906 TNPO2; (RefSeq) transportin-2 isoform X1\tK18727 TNPO2; transportin-2" }, { "name":"132213316 XPO1; (RefSeq) exportin-1 isoform X1\tK14290 XPO1; exportin-1" }, { "name":"132234743 XPO7; (RefSeq) exportin-7\tK18460 XPO7; exportin-7" }, { "name":"132235955 RANBP17; (RefSeq) ran-binding protein 17 isoform X1\tK24115 RANBP17; Ran-binding protein 17" }, { "name":"132225817 RANGAP1; (RefSeq) ran GTPase-activating protein 1 isoform X1\tK14319 RANGAP1; Ran GTPase-activating protein 1" }, { "name":"132218784 TAF15; (RefSeq) TATA-binding protein-associated factor 2N isoform X1\tK14651 TAF15; transcription initiation factor TFIID subunit 15" }, { "name":"132212235 nuclear transport factor 2-like\tK28773 NUTF2; nuclear transport factor 2" }, { "name":"132217453 NUTF2; (RefSeq) nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2" } ] }, { "name":"eIF4F and regulatory proteins", "children":[ { "name":"132216013 EIF4E; (RefSeq) eukaryotic translation initiation factor 4E isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132234314 EIF4E1B; (RefSeq) eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132236813 eukaryotic translation initiation factor 4E type 2-like\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132238357 EIF4E2; (RefSeq) eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132218064 EIF4A1; (RefSeq) eukaryotic initiation factor 4A-I isoform X1\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"132230208 EIF4A2; (RefSeq) eukaryotic initiation factor 4A-II isoform X1\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"132238648 eukaryotic initiation factor 4A-I\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"132230173 EIF4G1; (RefSeq) eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"132231573 EIF4G3; (RefSeq) eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"132241900 EIF4G2; (RefSeq) eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"132227633 EIF4B; (RefSeq) eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B" }, { "name":"132233179 EIF4H; (RefSeq) eukaryotic translation initiation factor 4H isoform X1\tK24086 EIF4H; translation initiation factor 4H" }, { "name":"132228645 EIF4EBP1; (RefSeq) eukaryotic translation initiation factor 4E-binding protein 1\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1" }, { "name":"132214871 EIF4EBP2; (RefSeq) eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2" }, { "name":"132235749 EIF4EBP3; (RefSeq) eukaryotic translation initiation factor 4E-binding protein 3\tK18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3" }, { "name":"132221931 EIF4ENIF1; (RefSeq) eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter" }, { "name":"132220997 ANGEL2; (RefSeq) protein angel homolog 2 isoform X1\tK18729 ANGEL; protein angel" }, { "name":"132231064 ANGEL1; (RefSeq) protein angel homolog 1 isoform X1\tK18729 ANGEL; protein angel" }, { "name":"132218069 FXR2; (RefSeq) RNA-binding protein FXR2 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132224373 FMR1; (RefSeq) fragile X messenger ribonucleoprotein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132230141 FXR1; (RefSeq) RNA-binding protein FXR1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132222849 CYFIP1; (RefSeq) cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"132235906 CYFIP2; (RefSeq) cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"132235894 GEMIN5; (RefSeq) gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5" }, { "name":"132222531 TACC3; (RefSeq) transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3" }, { "name":"132215001 CPEB3; (RefSeq) cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132221262 CPEB2; (RefSeq) cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132222724 CPEB1; (RefSeq) cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132235978 CPEB4; (RefSeq) cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132224148 DDX3X; (RefSeq) ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"132225536 ATP-dependent RNA helicase DDX3X-like isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"132235112 LOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX3X-like\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"132233254 GIGYF1; (RefSeq) GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"132238359 GIGYF2; (RefSeq) GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"132219661 PABPC1; (RefSeq) polyadenylate-binding protein 1 isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132224059 PABPC5; (RefSeq) polyadenylate-binding protein 5\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132224686 polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132225278 PABPC1L2B; (RefSeq) polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132231269 PABPC4; (RefSeq) polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132235533 PABPC4L; (RefSeq) polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132239910 PABPC1L; (RefSeq) LOW QUALITY PROTEIN: polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132220822 LOW QUALITY PROTEIN: polyadenylate-binding protein-interacting protein 1-like\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1" }, { "name":"132233701 PAIP1; (RefSeq) polyadenylate-binding protein-interacting protein 1 isoform X1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1" }, { "name":"132213231 PAIP2B; (RefSeq) polyadenylate-binding protein-interacting protein 2B\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2" }, { "name":"132235710 PAIP2; (RefSeq) polyadenylate-binding protein-interacting protein 2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2" }, { "name":"132237682 SKIC2; (RefSeq) superkiller complex protein 2 isoform X1\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]" }, { "name":"132241802 DEAF1; (RefSeq) deformed epidermal autoregulatory factor 1 homolog isoform X1\tK23041 DEAF1; deformed epidermal autoregulatory factor 1" }, { "name":"132215264 malignant T-cell-amplified sequence 1-like\tK07575 MCTS; malignant T-cell-amplified sequence" }, { "name":"132224895 MCTS1; (RefSeq) malignant T-cell-amplified sequence 1 isoform X1\tK07575 MCTS; malignant T-cell-amplified sequence" }, { "name":"132222044 DENR; (RefSeq) density-regulated protein\tK24272 DENR; density-regulated protein" } ] }, { "name":"APOBEC1-ACF complex", "children":[ { "name":"132227245 APOBEC1; (RefSeq) C->U-editing enzyme APOBEC-1\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]" }, { "name":"132214959 A1CF; (RefSeq) APOBEC1 complementation factor isoform X1\tK24978 A1CF; APOBEC1 complementation factor" } ] }, { "name":"Other transport factors", "children":[ { "name":"132227729 PYM1; (RefSeq) partner of Y14 and mago isoform X1\tK14294 WIBG; partner of Y14 and mago" }, { "name":"132234450 partner of Y14 and mago-like\tK14294 WIBG; partner of Y14 and mago" }, { "name":"132239281 partner of Y14 and mago-like\tK14294 WIBG; partner of Y14 and mago" }, { "name":"132214633 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132226481 heterogeneous nuclear ribonucleoprotein A1-like 3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132227698 HNRNPA1; (RefSeq) heterogeneous nuclear ribonucleoprotein A1 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132228014 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230497 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230498 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230499 heterogeneous nuclear ribonucleoprotein A1-like 3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230674 heterogeneous nuclear ribonucleoprotein A1-like 2 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132238490 HNRNPA3; (RefSeq) heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132218401 MSI2; (RefSeq) RNA-binding protein Musashi homolog 2 isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"132221671 MSI1; (RefSeq) RNA-binding protein Musashi homolog 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"132235270 DAZAP1; (RefSeq) DAZ-associated protein 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"132236910 HBS1L; (RefSeq) HBS1-like protein isoform X1\tK14416 HBS1; elongation factor 1 alpha-like protein" }, { "name":"132233786 PELO; (RefSeq) protein pelota homolog\tK06965 PELO; protein pelota" }, { "name":"132217079 PABPN1L; (RefSeq) embryonic polyadenylate-binding protein 2\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"132232327 polyadenylate-binding protein 2-like\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"132232638 polyadenylate-binding protein 2-like\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"132232833 polyadenylate-binding protein 2-like\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"132232834 polyadenylate-binding protein 2-like\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"132240642 PABPN1; (RefSeq) polyadenylate-binding protein 2 isoform X1\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"132217354 DDX19B; (RefSeq) ATP-dependent RNA helicase DDX19B isoform X1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]" }, { "name":"132217355 DDX19A; (RefSeq) ATP-dependent RNA helicase DDX19A isoform X1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]" }, { "name":"132222155 DDX25; (RefSeq) ATP-dependent RNA helicase DDX25 isoform X1\tK18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]" }, { "name":"132234613 XAB2; (RefSeq) pre-mRNA-splicing factor SYF1\tK12867 SYF1; pre-mRNA-splicing factor SYF1" }, { "name":"132227724 SARNP; (RefSeq) SAP domain-containing ribonucleoprotein isoform X1\tK18732 SARNP; SAP domain-containing ribonucleoprotein" }, { "name":"132231431 RCC1; (RefSeq) regulator of chromosome condensation isoform X1\tK11493 RCC1; regulator of chromosome condensation" }, { "name":"132212592 LARP6; (RefSeq) la-related protein 6\tK18733 LARP6; la-related protein 6" }, { "name":"132235725 PURA; (RefSeq) transcriptional activator protein Pur-alpha\tK21772 PURA; transcriptional activator protein Pur-alpha" }, { "name":"132211224 PURB; (RefSeq) LOW QUALITY PROTEIN: transcriptional activator protein Pur-beta\tK21799 PURB; transcriptional activator protein Pur-beta" }, { "name":"132225820 POLDIP3; (RefSeq) polymerase delta-interacting protein 3 isoform X1\tK22414 POLDIP3; polymerase delta-interacting protein 3" }, { "name":"132220466 ZC3H11A; (RefSeq) zinc finger CCCH domain-containing protein 11A\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11" }, { "name":"132226422 zinc finger CCCH domain-containing protein 11A-like\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11" }, { "name":"132228683 zinc finger CCCH domain-containing protein 11A-like\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11" }, { "name":"132236908 zinc finger CCCH domain-containing protein 11A-like\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11" }, { "name":"132216494 LENG8; (RefSeq) leukocyte receptor cluster member 8 isoform X1\tK23802 LENG8; SAC3 family protein LENG8\/THP3" }, { "name":"132219707 leukocyte receptor cluster member 8-like\tK23802 LENG8; SAC3 family protein LENG8\/THP3" }, { "name":"132238081 PATL2; (RefSeq) protein PAT1 homolog 2\tK24823 PATL2; protein PAT1 homolog 2" }, { "name":"132213021 UAP56-interacting factor-like\tK28772 FYTTD1; UAP56-interacting factor" }, { "name":"132230305 FYTTD1; (RefSeq) UAP56-interacting factor isoform X1\tK28772 FYTTD1; UAP56-interacting factor" } ] } ] }, { "name":"Surveillance factors", "children":[ { "name":"Surveillance complex", "children":[ { "name":"132224986 eukaryotic peptide chain release factor subunit 1-like\tK03265 ETF1; peptide chain release factor subunit 1" }, { "name":"132235701 ETF1; (RefSeq) eukaryotic peptide chain release factor subunit 1 isoform X1\tK03265 ETF1; peptide chain release factor subunit 1" }, { "name":"132215780 LOW QUALITY PROTEIN: eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like\tK03267 ERF3; peptide chain release factor subunit 3" }, { "name":"132223984 GSPT2; (RefSeq) eukaryotic peptide chain release factor GTP-binding subunit ERF3B\tK03267 ERF3; peptide chain release factor subunit 3" }, { "name":"132233094 GSPT1; (RefSeq) eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1\tK03267 ERF3; peptide chain release factor subunit 3" }, { "name":"132234786 UPF1; (RefSeq) regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"132242592 UPF2; (RefSeq) regulator of nonsense transcripts 2 isoform X1\tK14327 UPF2; regulator of nonsense transcripts 2" }, { "name":"132224699 UPF3B; (RefSeq) regulator of nonsense transcripts 3B isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"132228579 UPF3A; (RefSeq) regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" } ] }, { "name":"Protein phosphatase 2A", "children":[ { "name":"132228665 PPP2CB; (RefSeq) serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform isoform X1\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"132235650 PPP2CA; (RefSeq) serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"132216103 PPP2R1A; (RefSeq) serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A" }, { "name":"132240540 PPP2R1B; (RefSeq) serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A" }, { "name":"132214434 PPP2R2D; (RefSeq) serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"132219896 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform-like\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"132221673 PPP2R2C; (RefSeq) protein phosphatase 2, regulatory subunit B, gamma isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"132234697 PPP2R2A; (RefSeq) serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"132235812 PPP2R2B; (RefSeq) serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"132215534 PPP2R3A; (RefSeq) serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"132225218 PPP2R3B; (RefSeq) serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"132241666 PPP2R3C; (RefSeq) serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"132221258 PPP2R5A; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"132222895 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"132222994 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"132229944 PPP2R5C; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"132233401 PPP2R5E; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"132237309 PPP2R5D; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"132241449 PPP2R5B; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" } ] }, { "name":"Other surveillance factors", "children":[ { "name":"132233127 SMG1; (RefSeq) serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"132221330 SMG5; (RefSeq) nonsense-mediated mRNA decay factor SMG5 isoform X1\tK11125 SMG5; protein SMG5" }, { "name":"132218225 SMG6; (RefSeq) telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]" }, { "name":"132220275 SMG7; (RefSeq) nonsense-mediated mRNA decay factor SMG7 isoform X1\tK14409 SMG7; protein SMG7" }, { "name":"132218428 SMG8; (RefSeq) nonsense-mediated mRNA decay factor SMG8\tK18734 SMG8; protein SMG8" }, { "name":"132216777 SMG9; (RefSeq) nonsense-mediated mRNA decay factor SMG9 isoform X1\tK18735 SMG9; protein SMG9" }, { "name":"132233254 GIGYF1; (RefSeq) GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"132238359 GIGYF2; (RefSeq) GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"132211799 SECISBP2; (RefSeq) selenocysteine insertion sequence-binding protein 2 isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2" }, { "name":"132237491 SECISBP2L; (RefSeq) selenocysteine insertion sequence-binding protein 2-like isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2" }, { "name":"132216691 DHX34; (RefSeq) probable ATP-dependent RNA helicase DHX34\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]" }, { "name":"132226958 GTPBP1; (RefSeq) GTP-binding protein 1 isoform X1\tK24887 GTPBP1; GTP-binding protein 1" } ] } ] }, { "name":"Factors involved in mRNA localization", "children":[ { "name":"Cargo complex", "children":[ { "name":"132211953 PUM3; (RefSeq) pumilio homolog 3 isoform X1\tK14844 PUF6; pumilio homology domain family member 6" }, { "name":"132237066 MYO5A; (RefSeq) unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V" }, { "name":"132237117 MYO5C; (RefSeq) unconventional myosin-Vc\tK10357 MYO5; myosin V" }, { "name":"132240008 MYO5B; (RefSeq) unconventional myosin-Vb\tK10357 MYO5; myosin V" }, { "name":"132211778 BICD2; (RefSeq) protein bicaudal D homolog 2 isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"132227435 BICD1; (RefSeq) protein bicaudal D homolog 1 isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"132211713 EXD1; (RefSeq) piRNA biogenesis protein EXD1 isoform X1\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1" } ] }, { "name":"Factors that have mRNA localization signals", "children":[ { "name":"132219202 ACTG1; (RefSeq) actin, cytoplasmic 2\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"132236028 ACTB; (RefSeq) actin, cytoplasmic 1\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"132239702 MBP; (RefSeq) myelin basic protein isoform X1\tK17269 MBP; myelin basic protein" }, { "name":"132213546 VIM; (RefSeq) vimentin\tK07606 VIM; vimentin" }, { "name":"132217558 metallothionein-1E-like\tK14739 MT1_2; metallothionein 1\/2" }, { "name":"132217559 metallothionein-2A isoform X1\tK14739 MT1_2; metallothionein 1\/2" }, { "name":"132217560 metallothionein-1E\tK14739 MT1_2; metallothionein 1\/2" }, { "name":"132224666 metallothionein-1A-like\tK14739 MT1_2; metallothionein 1\/2" }, { "name":"132219747 MYC; (RefSeq) myc proto-oncogene protein\tK04377 MYC; Myc proto-oncogene protein" }, { "name":"132234788 GDF1; (RefSeq) embryonic growth\/differentiation factor 1\tK05495 GDF1; growth differentiation factor 1" }, { "name":"132232780 TBX6; (RefSeq) LOW QUALITY PROTEIN: T-box transcription factor TBX6\tK10180 TBX6; T-box protein 6" }, { "name":"132214392 NANOS1; (RefSeq) nanos homolog 1\tK18741 NANOS1; protein nanos 1" } ] }, { "name":"Trans-acting binding proteins", "children":[ { "name":"132239207 ZBP1; (RefSeq) Z-DNA-binding protein 1 isoform X1\tK12965 ZBP1; Z-DNA binding protein 1" }, { "name":"132212487 FUBP3; (RefSeq) far upstream element-binding protein 3 isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"132230913 FUBP1; (RefSeq) far upstream element-binding protein 1 isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"132235119 KHSRP; (RefSeq) far upstream element-binding protein 2\tK13210 FUBP; far upstream element-binding protein" }, { "name":"132211769 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"132214713 elongation factor 1-alpha 1-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"132228473 putative elongation factor 1-alpha-like 3\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"132230743 LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"132237151 EEF1A1; (RefSeq) elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"132239141 EEF1A2; (RefSeq) elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"132241538 EEF1G; (RefSeq) elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma" }, { "name":"132216849 heterogeneous nuclear ribonucleoproteins A2\/B1-like isoform X1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1" }, { "name":"132230837 heterogeneous nuclear ribonucleoproteins A2\/B1-like isoform X1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1" }, { "name":"132243047 HNRNPA2B1; (RefSeq) heterogeneous nuclear ribonucleoproteins A2\/B1 isoform X1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1" }, { "name":"132221379 HAX1; (RefSeq) HCLS1-associated protein X-1\tK16220 HAX1; HCLS1-associated protein X-1" }, { "name":"132238306 AGFG1; (RefSeq) arf-GAP domain and FG repeat-containing protein 1 isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1" }, { "name":"132220009 STAU2; (RefSeq) double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"132239273 STAU1; (RefSeq) double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"132243033 IGF2BP3; (RefSeq) insulin-like growth factor 2 mRNA-binding protein 3\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3" }, { "name":"132235300 PTBP1; (RefSeq) polypyrimidine tract-binding protein 1 isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1" }, { "name":"132215001 CPEB3; (RefSeq) cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132221262 CPEB2; (RefSeq) cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132222724 CPEB1; (RefSeq) cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132235978 CPEB4; (RefSeq) cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" } ] }, { "name":"Other mRNA localization factors", "children":[ { "name":"132218069 FXR2; (RefSeq) RNA-binding protein FXR2 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132224373 FMR1; (RefSeq) fragile X messenger ribonucleoprotein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132230141 FXR1; (RefSeq) RNA-binding protein FXR1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132222849 CYFIP1; (RefSeq) cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"132235906 CYFIP2; (RefSeq) cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"132227675 PCBP2; (RefSeq) poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"132215798 PCBP4; (RefSeq) poly(rC)-binding protein 4 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"132229981 PCBP3; (RefSeq) poly(rC)-binding protein 3 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"132241277 CAPRIN1; (RefSeq) caprin-1 isoform X1\tK18743 CAPRIN1; caprin-1" }, { "name":"132227418 CAPRIN2; (RefSeq) caprin-2 isoform X1\tK18744 CAPRIN2; caprin-2" }, { "name":"132230545 Y-box-binding protein 1-like\tK09276 YBX1; Y-box-binding protein 1" }, { "name":"132231156 YBX1; (RefSeq) Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1" } ] } ] }, { "name":"mRNA cycle factors", "children":[ { "name":"Common to processing body (P body) and stress granule", "children":[ { "name":"132230600 XRN1; (RefSeq) 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]" }, { "name":"132219786 AGO2; (RefSeq) protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"132231317 protein argonaute-1 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"132231318 AGO3; (RefSeq) protein argonaute-3 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"132231321 protein argonaute-4 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"132216013 EIF4E; (RefSeq) eukaryotic translation initiation factor 4E isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132234314 EIF4E1B; (RefSeq) eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132236813 eukaryotic translation initiation factor 4E type 2-like\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132238357 EIF4E2; (RefSeq) eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"132234786 UPF1; (RefSeq) regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"132224148 DDX3X; (RefSeq) ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"132225536 ATP-dependent RNA helicase DDX3X-like isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"132235112 LOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX3X-like\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"132240475 DDX6; (RefSeq) probable ATP-dependent RNA helicase DDX6 isoform X1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"132221145 MEX3A; (RefSeq) RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"132222753 MEX3B; (RefSeq) RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"132235257 MEX3D; (RefSeq) RNA-binding protein MEX3D\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"132240027 MEX3C; (RefSeq) RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"132242617 FASTK; (RefSeq) fas-activated serine\/threonine kinase isoform X1\tK08290 FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]" }, { "name":"132217046 LSM14A; (RefSeq) protein LSM14 homolog A isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"132239174 LSM14B; (RefSeq) protein LSM14 homolog B isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"132213250 PCBP1; (RefSeq) poly(rC)-binding protein 1\tK12889 PCBP1; poly(rC)-binding protein 1" }, { "name":"132227675 PCBP2; (RefSeq) poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"132230545 Y-box-binding protein 1-like\tK09276 YBX1; Y-box-binding protein 1" }, { "name":"132231156 YBX1; (RefSeq) Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1" }, { "name":"132215682 LIMD1; (RefSeq) LIM domain-containing protein 1 isoform X1\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"132217037 WTIP; (RefSeq) Wilms tumor protein 1-interacting protein isoform X1\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"132240476 AJUBA; (RefSeq) LIM domain-containing protein ajuba isoform X1\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"132227245 APOBEC1; (RefSeq) C->U-editing enzyme APOBEC-1\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]" }, { "name":"132225941 DNA dC->dU-editing enzyme APOBEC-3B-like\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132226943 DNA dC->dU-editing enzyme APOBEC-3C-like\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132226948 DNA dC->dU-editing enzyme APOBEC-3G-like isoform X1\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132226949 DNA dC->dU-editing enzyme APOBEC-3Ca-like\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132226950 DNA dC->dU-editing enzyme APOBEC-3G-like isoform X1\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132226952 DNA dC->dU-editing enzyme APOBEC-3G-like\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132226953 DNA dC->dU-editing enzyme APOBEC-3G-like isoform X1\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132234757 DNA dC->dU-editing enzyme APOBEC3-like\tK18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]" }, { "name":"132220776 MOV10; (RefSeq) helicase MOV-10 isoform X1\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]" }, { "name":"132231539 PNRC2; (RefSeq) proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2" }, { "name":"132233544 TNPO1; (RefSeq) transportin-1 isoform X1\tK18752 TNPO1; transportin-1" }, { "name":"132233127 SMG1; (RefSeq) serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"132221330 SMG5; (RefSeq) nonsense-mediated mRNA decay factor SMG5 isoform X1\tK11125 SMG5; protein SMG5" }, { "name":"132218225 SMG6; (RefSeq) telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]" }, { "name":"132220275 SMG7; (RefSeq) nonsense-mediated mRNA decay factor SMG7 isoform X1\tK14409 SMG7; protein SMG7" }, { "name":"132216905 mRNA decay activator protein ZFP36 isoform X1\tK15308 TTP; tristetraprolin" }, { "name":"132213419 ZFP36L2; (RefSeq) mRNA decay activator protein ZFP36L2\tK18753 ZFP36L; butyrate response factor" }, { "name":"132232787 ZFP36L1; (RefSeq) mRNA decay activator protein ZFP36L1 isoform X1\tK18753 ZFP36L; butyrate response factor" }, { "name":"132229535 LIN28A; (RefSeq) protein lin-28 homolog A\tK18754 LIN28; protein lin-28" }, { "name":"132236676 LIN28B; (RefSeq) protein lin-28 homolog B\tK18754 LIN28; protein lin-28" }, { "name":"132222033 HTT; (RefSeq) huntingtin isoform X1\tK04533 HD; huntingtin" }, { "name":"132227420 IPO8; (RefSeq) importin-8 isoform X1\tK18755 IPO8; importin-8" }, { "name":"132214948 BICC1; (RefSeq) protein bicaudal C homolog 1 isoform X1\tK18756 BICC1; protein bicaudal C" }, { "name":"132214633 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132226481 heterogeneous nuclear ribonucleoprotein A1-like 3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132227698 HNRNPA1; (RefSeq) heterogeneous nuclear ribonucleoprotein A1 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132228014 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230497 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230498 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230499 heterogeneous nuclear ribonucleoprotein A1-like 3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230674 heterogeneous nuclear ribonucleoprotein A1-like 2 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132238490 HNRNPA3; (RefSeq) heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"132230901 PRKACB; (RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"132234959 PRKACA; (RefSeq) cAMP-dependent protein kinase catalytic subunit alpha\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"132235541 LARP1B; (RefSeq) la-related protein 1B isoform X1\tK18757 LARP1; la-related protein 1" }, { "name":"132235891 LARP1; (RefSeq) la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1" }, { "name":"132221843 ATXN2; (RefSeq) ataxin-2 isoform X1\tK23625 ATXN2; ataxin-2" }, { "name":"132232803 ATXN2L; (RefSeq) ataxin-2-like protein isoform X1\tK23625 ATXN2; ataxin-2" } ] }, { "name":"P-body specific factors", "children":[ { "name":"132233357 DCP2; (RefSeq) m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]" }, { "name":"132215289 DCP1A; (RefSeq) mRNA-decapping enzyme 1A isoform X1\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]" }, { "name":"132228095 DCP1B; (RefSeq) mRNA-decapping enzyme 1B isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]" }, { "name":"132239750 U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1" }, { "name":"132237721 LSM2; (RefSeq) U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"132212790 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132215476 LSM3; (RefSeq) U6 snRNA-associated Sm-like protein LSm3 isoform X1\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132226225 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132226392 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132234251 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132234807 LSM4; (RefSeq) U6 snRNA-associated Sm-like protein LSm4 isoform X1\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4" }, { "name":"132211828 LOW QUALITY PROTEIN: U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"132243104 LSM5; (RefSeq) U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"132235486 LSM6; (RefSeq) U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6" }, { "name":"132235235 LSM7; (RefSeq) U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7" }, { "name":"132242681 LSM8; (RefSeq) LSM8 homolog, U6 small nuclear RNA associated isoform X1\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8" }, { "name":"132216736 KLC3; (RefSeq) kinesin light chain 3 isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"132228633 KLC1; (RefSeq) kinesin light chain 1 isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"132237305 KLC4; (RefSeq) kinesin light chain 4 isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"132241380 KLC2; (RefSeq) kinesin light chain 2 isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"132237066 MYO5A; (RefSeq) unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V" }, { "name":"132237117 MYO5C; (RefSeq) unconventional myosin-Vc\tK10357 MYO5; myosin V" }, { "name":"132240008 MYO5B; (RefSeq) unconventional myosin-Vb\tK10357 MYO5; myosin V" }, { "name":"132215246 TUBAL3; (RefSeq) tubulin alpha chain-like 3 isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"132221234 tubulin alpha-1B chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"132221939 tubulin alpha-3 chain isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"132222152 tubulin alpha-3 chain\tK07374 TUBA; tubulin alpha" }, { "name":"132227542 TUBA1B; (RefSeq) tubulin alpha-1B chain\tK07374 TUBA; tubulin alpha" }, { "name":"132227545 tubulin alpha-1A chain\tK07374 TUBA; tubulin alpha" }, { "name":"132227546 tubulin alpha-1C chain\tK07374 TUBA; tubulin alpha" }, { "name":"132228220 tubulin alpha-8 chain isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"132238258 TUBA4A; (RefSeq) tubulin alpha-4A chain\tK07374 TUBA; tubulin alpha" }, { "name":"132238261 tubulin alpha-1D chain\tK07374 TUBA; tubulin alpha" }, { "name":"132242946 tubulin alpha-1C chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"132215001 CPEB3; (RefSeq) cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132221262 CPEB2; (RefSeq) cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132222724 CPEB1; (RefSeq) cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132235978 CPEB4; (RefSeq) cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"132235894 GEMIN5; (RefSeq) gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5" }, { "name":"132222531 TACC3; (RefSeq) transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3" }, { "name":"132219151 TNRC6C; (RefSeq) trinucleotide repeat-containing gene 6C protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"132226922 TNRC6B; (RefSeq) trinucleotide repeat-containing gene 6B protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"132232675 TNRC6A; (RefSeq) trinucleotide repeat-containing gene 6A protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"132217519 CNOT1; (RefSeq) CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1" }, { "name":"132227928 CNOT2; (RefSeq) CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"132216534 CNOT3; (RefSeq) CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"132242794 CNOT4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"132217436 CNOT6L; (RefSeq) CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"132234590 CNOT6; (RefSeq) CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"132228705 CNOT7; (RefSeq) CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"132235895 CNOT8; (RefSeq) CCR4-NOT transcription complex subunit 8 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"132217042 GARRE1; (RefSeq) granule associated Rac and RHOG effector protein 1 isoform X1\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1" }, { "name":"132238360 DIS3L2; (RefSeq) DIS3-like exonuclease 2 isoform X1\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]" }, { "name":"132227762 PAN2; (RefSeq) PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]" }, { "name":"132228124 PAN3; (RefSeq) PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3" }, { "name":"132218815 TOB1; (RefSeq) protein Tob1\tK14443 TOB; protein Tob\/BTG" }, { "name":"132221007 BTG2; (RefSeq) protein BTG2\tK14443 TOB; protein Tob\/BTG" }, { "name":"132225825 TOB2; (RefSeq) protein Tob2\tK14443 TOB; protein Tob\/BTG" }, { "name":"132228010 BTG1; (RefSeq) protein BTG1\tK14443 TOB; protein Tob\/BTG" }, { "name":"132230020 BTG3; (RefSeq) protein BTG3\tK14443 TOB; protein Tob\/BTG" }, { "name":"132242027 BTG4; (RefSeq) protein BTG4\tK14443 TOB; protein Tob\/BTG" }, { "name":"132221931 EIF4ENIF1; (RefSeq) eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter" }, { "name":"132241114 PATL1; (RefSeq) protein PAT1 homolog 1 isoform X1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1" }, { "name":"132212081 EDC3; (RefSeq) enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3" }, { "name":"132217450 EDC4; (RefSeq) enhancer of mRNA-decapping protein 4 isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4" }, { "name":"132216335 NANOS2; (RefSeq) nanos homolog 2\tK18760 NANOS2; protein nanos 2" }, { "name":"132234946 NANOS3; (RefSeq) nanos homolog 3\tK18761 NANOS3; protein nanos 3" }, { "name":"132242592 UPF2; (RefSeq) regulator of nonsense transcripts 2 isoform X1\tK14327 UPF2; regulator of nonsense transcripts 2" }, { "name":"132224699 UPF3B; (RefSeq) regulator of nonsense transcripts 3B isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"132228579 UPF3A; (RefSeq) regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"132240879 TRIM21; (RefSeq) E3 ubiquitin-protein ligase TRIM21 isoform X1\tK10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]" }, { "name":"132215454 TRIM71; (RefSeq) E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]" }, { "name":"132241523 POLR2G; (RefSeq) DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7" }, { "name":"132213473 EIF2AK2; (RefSeq) interferon-induced, double-stranded RNA-activated protein kinase isoform X1\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"132226275 protein ZAR1-like\tK18762 ZAR1; zygote arrest protein 1" }, { "name":"132227458 ZAR1; (RefSeq) zygote arrest protein 1\tK18762 ZAR1; zygote arrest protein 1" }, { "name":"132220145 YTHDF3; (RefSeq) YTH domain-containing family protein 3 isoform X1\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"132231421 YTHDF2; (RefSeq) YTH domain-containing family protein 2\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"132239146 YTHDF1; (RefSeq) YTH domain-containing family protein 1\tK20102 YTHDF; YTH domain-containing family protein" } ] }, { "name":"Stress granule specific factors", "children":[ { "name":"132213245 TIA1; (RefSeq) cytotoxic granule associated RNA binding protein TIA1 isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"132214399 TIAL1; (RefSeq) nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"132219661 PABPC1; (RefSeq) polyadenylate-binding protein 1 isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132224059 PABPC5; (RefSeq) polyadenylate-binding protein 5\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132224686 polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132225278 PABPC1L2B; (RefSeq) polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132231269 PABPC4; (RefSeq) polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132235533 PABPC4L; (RefSeq) polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132239910 PABPC1L; (RefSeq) LOW QUALITY PROTEIN: polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"132220009 STAU2; (RefSeq) double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"132239273 STAU1; (RefSeq) double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"132218069 FXR2; (RefSeq) RNA-binding protein FXR2 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132224373 FMR1; (RefSeq) fragile X messenger ribonucleoprotein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132230141 FXR1; (RefSeq) RNA-binding protein FXR1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"132239207 ZBP1; (RefSeq) Z-DNA-binding protein 1 isoform X1\tK12965 ZBP1; Z-DNA binding protein 1" }, { "name":"132234669 ELAVL1; (RefSeq) ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"132235878 G3BP1; (RefSeq) ras GTPase-activating protein-binding protein 1 isoform X1\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"132217867 G3BP2; (RefSeq) ras GTPase-activating protein-binding protein 2 isoform X1\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2" }, { "name":"132230533 EIF2A; (RefSeq) eukaryotic translation initiation factor 2A isoform X1\tK15026 EIF2A; translation initiation factor 2A" }, { "name":"132236048 EIF3B; (RefSeq) eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B" }, { "name":"132218064 EIF4A1; (RefSeq) eukaryotic initiation factor 4A-I isoform X1\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"132230208 EIF4A2; (RefSeq) eukaryotic initiation factor 4A-II isoform X1\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"132238648 eukaryotic initiation factor 4A-I\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"132219180 EIF4A3; (RefSeq) eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"132227246 eukaryotic initiation factor 4A-III-like\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"132227633 EIF4B; (RefSeq) eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B" }, { "name":"132230173 EIF4G1; (RefSeq) eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"132231573 EIF4G3; (RefSeq) eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"132241900 EIF4G2; (RefSeq) eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"132223240 RPS6KA6; (RefSeq) ribosomal protein S6 kinase alpha-6 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"132223323 RPS6KA3; (RefSeq) ribosomal protein S6 kinase alpha-3 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"132231484 RPS6KA1; (RefSeq) ribosomal protein S6 kinase alpha-1 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"132236704 RPS6KA2; (RefSeq) ribosomal protein S6 kinase alpha-2 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"132234581 RACK1; (RefSeq) small ribosomal subunit protein RACK1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein" }, { "name":"132212630 TRAF2; (RefSeq) TNF receptor-associated factor 2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]" }, { "name":"132223495 nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223496 NXF3; (RefSeq) LOW QUALITY PROTEIN: nuclear RNA export factor 3\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223501 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223503 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132223504 nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132236614 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor" }, { "name":"132241517 NXF1; (RefSeq) nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor" }, { "name":"132225119 HDAC6; (RefSeq) histone deacetylase 6 isoform X1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]" }, { "name":"132228423 TDRD3; (RefSeq) tudor domain-containing protein 3 isoform X1\tK18404 TDRD3; tudor domain-containing protein 3" }, { "name":"132215091 LARP4B; (RefSeq) la-related protein 4B isoform X1\tK18763 LARP4; la-related protein 4" }, { "name":"132227580 LARP4; (RefSeq) la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4" } ] } ] } ] }, { "name":"mRNA degradation factors", "children":[ { "name":"5'-3' decay", "children":[ { "name":"Decapping complex", "children":[ { "name":"132215289 DCP1A; (RefSeq) mRNA-decapping enzyme 1A isoform X1\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]" }, { "name":"132228095 DCP1B; (RefSeq) mRNA-decapping enzyme 1B isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]" }, { "name":"132233357 DCP2; (RefSeq) m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]" }, { "name":"132240475 DDX6; (RefSeq) probable ATP-dependent RNA helicase DDX6 isoform X1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"132212081 EDC3; (RefSeq) enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3" }, { "name":"132217450 EDC4; (RefSeq) enhancer of mRNA-decapping protein 4 isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4" }, { "name":"132241114 PATL1; (RefSeq) protein PAT1 homolog 1 isoform X1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1" } ] }, { "name":"Lsm complex", "children":[ { "name":"132239750 U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1" }, { "name":"132237721 LSM2; (RefSeq) U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"132212790 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132215476 LSM3; (RefSeq) U6 snRNA-associated Sm-like protein LSm3 isoform X1\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132226225 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132226392 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132234251 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"132234807 LSM4; (RefSeq) U6 snRNA-associated Sm-like protein LSm4 isoform X1\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4" }, { "name":"132211828 LOW QUALITY PROTEIN: U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"132243104 LSM5; (RefSeq) U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"132235486 LSM6; (RefSeq) U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6" }, { "name":"132235235 LSM7; (RefSeq) U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7" }, { "name":"132242681 LSM8; (RefSeq) LSM8 homolog, U6 small nuclear RNA associated isoform X1\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8" } ] }, { "name":"5' exonucleases", "children":[ { "name":"132230600 XRN1; (RefSeq) 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]" }, { "name":"132239298 XRN2; (RefSeq) 5'-3' exoribonuclease 2 isoform X1\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]" }, { "name":"132215569 NUDT16; (RefSeq) U8 snoRNA-decapping enzyme\tK16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]" } ] }, { "name":"Other 5'-3' decay factors", "children":[ { "name":"132221773 DCPS; (RefSeq) m7GpppX diphosphatase isoform X1\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"132218603 HELZ; (RefSeq) probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]" } ] } ] }, { "name":"3'-5' decay", "children":[ { "name":"Core exosome factors", "children":[ { "name":"132214194 EXOSC1; (RefSeq) exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4" }, { "name":"132212488 EXOSC2; (RefSeq) exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4" }, { "name":"132216822 exosome complex component RRP4-like\tK03679 RRP4; exosome complex component RRP4" }, { "name":"132212164 EXOSC3; (RefSeq) exosome complex component RRP40 isoform X1\tK03681 RRP40; exosome complex component RRP40" }, { "name":"132219844 EXOSC4; (RefSeq) exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41" }, { "name":"132216835 EXOSC5; (RefSeq) exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46" }, { "name":"132217360 EXOSC6; (RefSeq) exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3" }, { "name":"132215695 EXOSC7; (RefSeq) exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42" }, { "name":"132228254 EXOSC8; (RefSeq) exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43" }, { "name":"132234575 EXOSC9; (RefSeq) exosome complex component RRP45 isoform X1\tK03678 RRP45; exosome complex component RRP45" } ] }, { "name":"Exosome cofactors", "children":[ { "name":"132228436 DIS3; (RefSeq) exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]" }, { "name":"132235350 DIS3L; (RefSeq) DIS3-like exonuclease 1 isoform X1\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]" }, { "name":"132220031 exosome component 10-like\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]" }, { "name":"132231689 EXOSC10; (RefSeq) exosome component 10 isoform X1\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]" }, { "name":"132213278 C1D; (RefSeq) nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1" }, { "name":"132226609 nuclear nucleic acid-binding protein C1D-like\tK12592 C1D; exosome complex protein LRP1" }, { "name":"132227852 nuclear nucleic acid-binding protein C1D-like\tK12592 C1D; exosome complex protein LRP1" }, { "name":"132229281 nuclear nucleic acid-binding protein C1D-like\tK12592 C1D; exosome complex protein LRP1" }, { "name":"132217200 MPHOSPH6; (RefSeq) M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type" }, { "name":"132226005 M-phase phosphoprotein 6-like\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type" }, { "name":"132229738 M-phase phosphoprotein 6-like\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type" }, { "name":"132235396 probable ATP-dependent RNA helicase DDX60 isoform X1\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]" }, { "name":"132235397 probable ATP-dependent RNA helicase DDX60 isoform X1\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]" } ] }, { "name":"TRAMP complex", "children":[ { "name":"132217597 TENT4B; (RefSeq) terminal nucleotidyltransferase 4B isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"132233654 TENT4A; (RefSeq) terminal nucleotidyltransferase 4A isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"132212152 ZCCHC7; (RefSeq) zinc finger CCHC domain-containing protein 7\tK12597 AIR1_2; protein AIR1\/2" }, { "name":"132233798 MTREX; (RefSeq) exosome RNA helicase MTR4 isoform X1\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]" } ] }, { "name":"Ski complex", "children":[ { "name":"132237682 SKIC2; (RefSeq) superkiller complex protein 2 isoform X1\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]" }, { "name":"132233409 SKIC3; (RefSeq) superkiller complex protein 3\tK12600 SKI3; superkiller protein 3" }, { "name":"132222781 SKIC8; (RefSeq) superkiller complex protein 8\tK12602 WDR61; WD repeat-containing protein 61" } ] }, { "name":"Ccr4-NOT complex", "children":[ { "name":"132217436 CNOT6L; (RefSeq) CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"132234590 CNOT6; (RefSeq) CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"132217519 CNOT1; (RefSeq) CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1" }, { "name":"132227928 CNOT2; (RefSeq) CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"132216534 CNOT3; (RefSeq) CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"132242794 CNOT4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"132228705 CNOT7; (RefSeq) CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"132235895 CNOT8; (RefSeq) CCR4-NOT transcription complex subunit 8 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"132238234 CNOT9; (RefSeq) CCR4-NOT transcription complex subunit 9\tK12606 RCD1; CCR4-NOT transcription complex subunit 9" }, { "name":"132215643 CNOT10; (RefSeq) CCR4-NOT transcription complex subunit 10 isoform X1\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10" } ] }, { "name":"Pan complex", "children":[ { "name":"132227762 PAN2; (RefSeq) PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]" }, { "name":"132228124 PAN3; (RefSeq) PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3" } ] }, { "name":"Other 3'-5' decay factors", "children":[ { "name":"132233106 PARN; (RefSeq) poly(A)-specific ribonuclease PARN isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]" }, { "name":"132236726 PNLDC1; (RefSeq) poly(A)-specific ribonuclease PNLDC1 isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]" }, { "name":"132230029 DHX36; (RefSeq) ATP-dependent DNA\/RNA helicase DHX36 isoform X1\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]" }, { "name":"132218815 TOB1; (RefSeq) protein Tob1\tK14443 TOB; protein Tob\/BTG" }, { "name":"132221007 BTG2; (RefSeq) protein BTG2\tK14443 TOB; protein Tob\/BTG" }, { "name":"132225825 TOB2; (RefSeq) protein Tob2\tK14443 TOB; protein Tob\/BTG" }, { "name":"132228010 BTG1; (RefSeq) protein BTG1\tK14443 TOB; protein Tob\/BTG" }, { "name":"132230020 BTG3; (RefSeq) protein BTG3\tK14443 TOB; protein Tob\/BTG" }, { "name":"132242027 BTG4; (RefSeq) protein BTG4\tK14443 TOB; protein Tob\/BTG" }, { "name":"132234319 CSF2; (RefSeq) granulocyte-macrophage colony-stimulating factor\tK05427 CSF2; granulocyte-macrophage colony-stimulating factor" }, { "name":"132235524 NOCT; (RefSeq) nocturnin isoform X1\tK18764 NOCT; nocturnin [EC:3.1.3.108]" }, { "name":"132228685 ERI1; (RefSeq) 3'-5' exoribonuclease 1 isoform X1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]" }, { "name":"132232628 ERI2; (RefSeq) ERI1 exoribonuclease 2 isoform X1\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]" }, { "name":"132221773 DCPS; (RefSeq) m7GpppX diphosphatase isoform X1\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"132215261 PDE12; (RefSeq) 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]" }, { "name":"132222777 IREB2; (RefSeq) iron-responsive element-binding protein 2 isoform X1\tK22416 IREB2; iron-responsive element-binding protein 2" }, { "name":"132218603 HELZ; (RefSeq) probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]" }, { "name":"132239135 HELZ2; (RefSeq) helicase with zinc finger domain 2 isoform X1\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]" }, { "name":"132230585 NRDE2; (RefSeq) nuclear exosome regulator NRDE2\tK26109 NRDE2; nuclear exosome regulator NRDE2" }, { "name":"132216903 SAMD4B; (RefSeq) protein Smaug homolog 2 isoform X1\tK27396 SMG; protein Smaug" }, { "name":"132234413 SAMD4A; (RefSeq) protein Smaug homolog 1 isoform X1\tK27396 SMG; protein Smaug" }, { "name":"132211875 FOCAD; (RefSeq) focadhesin\tK27498 FOCAD; focadhesin" } ] } ] }, { "name":"Other degradation factors", "children":[ { "name":"RNases", "children":[ { "name":"132223068 ribonuclease pancreatic-like\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]" }, { "name":"132223396 ribonuclease pancreatic-like\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]" }, { "name":"132223511 RNASE2; (RefSeq) non-secretory ribonuclease\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]" }, { "name":"132239603 ribonuclease pancreatic-like isoform X1\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]" }, { "name":"132239639 ribonuclease pancreatic-like\tK01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]" }, { "name":"132239571 ribonuclease 4-like\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132239617 ribonuclease 4-like isoform X1\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132239625 ribonuclease 4-like isoform X1\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132239651 ribonuclease 4-like\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132239660 ribonuclease 4-like\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132239675 ribonuclease 4-like\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132239699 ribonuclease 4-like\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132239709 ribonuclease 4-like\tK16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]" }, { "name":"132222972 ribonuclease K6-like\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]" }, { "name":"132223311 RNASE6; (RefSeq) ribonuclease K6\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]" }, { "name":"132239802 ribonuclease 7-like\tK01172 RNASE6_7_8; ribonuclease 6\/7\/8 [EC:3.1.27.-]" }, { "name":"132222645 RNASE11; (RefSeq) probable ribonuclease 11\tK16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]" }, { "name":"132224413 ZC3H12B; (RefSeq) probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"132231299 ZC3H12A; (RefSeq) endoribonuclease ZC3H12A isoform X1\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"132236800 ZC3H12D; (RefSeq) probable ribonuclease ZC3H12D isoform X1\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"132240605 ZC3H12C; (RefSeq) probable ribonuclease ZC3H12C isoform X1\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" } ] } ] } ] } ] }, { "name":"Prokaryotic type", "children":[ { "name":"Bacterial mRNA degradation factors", "children":[ { "name":"RNA degradosome components", "children":[ { "name":"Ribonucreases", "children":[ { "name":"132233664 DROSHA; (RefSeq) ribonuclease 3 isoform X1\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"132240531 REXO2; (RefSeq) oligoribonuclease, mitochondrial\tK13288 orn; oligoribonuclease [EC:3.1.-.-]" } ] }, { "name":"Helicases" }, { "name":"Other RNA degradosome components", "children":[ { "name":"132218146 ENO3; (RefSeq) beta-enolase isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"132225863 LOW QUALITY PROTEIN: alpha-enolase-like\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"132227223 ENO2; (RefSeq) gamma-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"132231722 ENO1; (RefSeq) alpha-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"132213346 PNPT1; (RefSeq) polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"132215207 PFKP; (RefSeq) ATP-dependent 6-phosphofructokinase, platelet type isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"132227507 PFKM; (RefSeq) ATP-dependent 6-phosphofructokinase, muscle type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"132229934 PFKL; (RefSeq) ATP-dependent 6-phosphofructokinase, liver type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" } ] } ] }, { "name":"Other RNA degradation factors", "children":[ { "name":"Chaperones", "children":[ { "name":"132235697 HSPA9; (RefSeq) stress-70 protein, mitochondrial isoform X1\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"132238084 HSPD1; (RefSeq) 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" } ] }, { "name":"Others" }, { "name":"Bacterial Small RNA Regulators" } ] } ] }, { "name":"Archeal mRNA degradation factors", "children":[ { "name":"Exosome components", "children":[ { "name":"Core exosome", "children":[ { "name":"132212488 EXOSC2; (RefSeq) exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4" }, { "name":"132216822 exosome complex component RRP4-like\tK03679 RRP4; exosome complex component RRP4" }, { "name":"132214194 EXOSC1; (RefSeq) exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4" } ] }, { "name":"Cofactors", "children":[ { "name":"132219844 EXOSC4; (RefSeq) exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41" }, { "name":"132215695 EXOSC7; (RefSeq) exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42" } ] }, { "name":"Others" } ] } ] } ] } ] }