{
	"name":"mea03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"Mex_1p2498 phr; deoxyribodipyrimidine photolyase (DNA photolyase)\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"Mex_1p1366 ung; Uracil-DNA glycosylase (UDG)\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"Mex_1p0707 Putative 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"Mex_1p3392 mutY; A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"Mex_1p0411 nth; endonuclease III DNA glycosylase\/apyrimidinic (AP) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"Mex_1p2915 hypothetical protein\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"Mex_1p3881 putative Endonuclease III (DNA-(apurinic or apyrimidinic site) lyase)\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex"
					},
					{
						"name":"DNA polymerase epsilon complex"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex"
					},
					{
						"name":"Cul4-DDB2 complex"
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex"
					},
					{
						"name":"Cul4-CSA complex"
					},
					{
						"name":"Other TCR factor"
					}
					]
				},
				{
					"name":"TFIIH complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Other NER factors"
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"MutL homologs"
				},
				{
					"name":"DNA polymerase delta complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex"
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex"
				},
				{
					"name":"BRCA complex"
				},
				{
					"name":"RecA family proteins"
				},
				{
					"name":"Rad52 family proteins"
				},
				{
					"name":"Rad54 family proteins"
				},
				{
					"name":"RecQ family DNA helicases"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Protein phosphatase 4"
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex"
				},
				{
					"name":"Other HR factors"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex"
				},
				{
					"name":"MRX complex"
				},
				{
					"name":"DNA Ligase 4 complex"
				},
				{
					"name":"X-family DNA polymerases"
				},
				{
					"name":"Other NHEJ factors"
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors"
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others"
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"B-family DNA polymerases"
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group"
			},
			{
				"name":"Other TLS factors"
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex"
			},
			{
				"name":"HRAD17(Rad24)-RFC complex"
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex"
			},
			{
				"name":"FPC (fork protection complex)"
			},
			{
				"name":"Triple T complex"
			},
			{
				"name":"BAG6-UBL4A-GET4 complex"
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases"
			},
			{
				"name":"Nucleases"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"PSO4 complex"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"Mex_1p0202 putative mutator MutT protein precursor; putative NTP pyrophosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Mex_1p1386 putative Nudix hydrolase family protein, putative pyrophosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Mex_1p4696 putative GDP-mannose mannosyl hydrolase (nudD)\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Mex_1p1415 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"Mex_1p4715 ada; fused DNA-binding transcriptional dual regulator; O6-methylguanine-DNA methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"Mex_1p2498 phr; deoxyribodipyrimidine photolyase (DNA photolyase)\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"Mex_1p1366 ung; Uracil-DNA glycosylase (UDG)\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"Mex_1p2307 ung; Uracil-DNA glycosylase superfamily protein (DNA replication, recombination and repair)\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"Mex_1p2880 conserved hypothetical protein with DNA glycosylase domain; Uracil DNA glycosylase superfamily\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"Mex_1p4641 putative phage DNA polymerase\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"Mex_1p0079 putative 3-methyladenine DNA glycosylase\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"Mex_1p3118 conserved hypothetical protein; putative DNA glycosylase\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"Mex_1p0707 Putative 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"Mex_1p3392 mutY; A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"Mex_1p4702 tag; 3-methyl-adenine DNA glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"Mex_1p4436 mutM; Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) (DNA-(apurinic or apyrimidinic site) lyase mutM) (AP lyase mutM)\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"Mex_1p0411 nth; endonuclease III DNA glycosylase\/apyrimidinic (AP) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"Mex_1p2915 hypothetical protein\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"Mex_1p3881 putative Endonuclease III (DNA-(apurinic or apyrimidinic site) lyase)\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"Mex_1p1930 xthA; Exodeoxyribonuclease III (Exonuclease III) (EXO III) (AP endonuclease VI)\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					},
					{
						"name":"Mex_1p4420 xthA; Exodeoxyribonuclease III (Exonuclease III) (EXO III) (AP endonuclease VI)\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					},
					{
						"name":"Mex_1p2437 nfi; Endonuclease V (Deoxyinosine 3'endonuclease) (Deoxyribonuclease V) (DNase V)\tK05982 nfi; deoxyribonuclease V [EC:3.1.21.7]"
					}
					]
				},
				{
					"name":"RecJ",
					"children":[
					{
						"name":"Mex_1p2959 recJ; putative single-strand DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					},
					{
						"name":"Mex_2p0507 Single-stranded-DNA-specific exonuclease protein\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"Mex_1p5091 dnlJ; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"Mex_2p0992 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"Mex_1p2436 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"Mex_1p0099 Excinuclease ABC, A subunit\tK03701 uvrA; excinuclease ABC subunit A"
					},
					{
						"name":"Mex_1p4267 uvrA; DNA excision repair enzyme subunit, with UvrBC\tK03701 uvrA; excinuclease ABC subunit A"
					},
					{
						"name":"Mex_1p4445 uvrB; UvrABC system protein B (UvrB protein) (Excinuclease ABC subunit B)\tK03702 uvrB; excinuclease ABC subunit B"
					},
					{
						"name":"Mex_1p3083 uvrC; DNA exisiton repair enzyme together with UvrAB\tK03703 uvrC; excinuclease ABC subunit C"
					},
					{
						"name":"Mex_1p0214 uvrD; DNA-dependent ATPase I and helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_1p2804 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0399 putative ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0508 putative DNA-dependent ATPase I and helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0726 putative DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_1p2436 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p5091 dnlJ; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"Mex_2p0992 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"Mex_1p4405 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"Mex_1p4406 rpoC; RNA polymerase, beta prime subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"Mex_1p2167 rpoA; DNA-directed RNA polymerase alpha chain (RNAP alpha subunit) (Transcriptase alpha chain) (RNA polymerase alpha subunit)\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						},
						{
							"name":"Mex_1p3409 rpoZ; DNA-directed RNA polymerase omega chain (RNAP omega subunit) (Transcriptase omega chain) (RNA polymerase omega subunit)\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)",
						"children":[
						{
							"name":"Mex_1p1061 DEAD\/DEAH box helicase domain protein\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
						},
						{
							"name":"Mex_1p4552 mfd; transcription repair coupling protein, ATP-dependent helicase\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"Mex_1p4678 mutS; DNA mismatch repair protein mutS\tK03555 mutS; DNA mismatch repair protein MutS"
					}
					]
				},
				{
					"name":"Molecular matchmaker",
					"children":[
					{
						"name":"Mex_1p4660 mutL; DNA mismatch repair protein mutL\tK03572 mutL; DNA mismatch repair protein MutL"
					}
					]
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases",
					"children":[
					{
						"name":"Mex_2p0530 putative Exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
					},
					{
						"name":"Mex_1p4247 xseA; putative exonuclease VII, large subunit OB-fold nucleic acid binding domain\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
					},
					{
						"name":"Mex_1p4705 xseB; exodeoxyribonuclease VII small subunit (exonuclease VII small subunit)\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
					}
					]
				},
				{
					"name":"DNA polymerase III holoenzyme",
					"children":[
					{
						"name":"Mex_1p0816 dnaE; DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"Mex_2p0727 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p0002 dnaN; DNA polymerase III, beta-subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p5105 conserved hypothetical protein\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p1478 putative DNA polymerase III, delta subunit, holA\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p4581 holB; DNA polymerase III, delta prime subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p0217 hypothetical protein, putative exonuclease domain\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p1378 dnaQ; DNA polymerase III epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"Mex_2p0510 putative Exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"Mex_2p0720 dnaQ; DNA polymerase III epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"Mex_1p1794 dnaX; DNA polymerase III, tau and gamma subunits\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"Mex_1p5091 dnlJ; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"Mex_2p0992 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"Mex_1p0214 uvrD; DNA-dependent ATPase I and helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_1p2804 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0399 putative ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0508 putative DNA-dependent ATPase I and helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0726 putative DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"Mex_1p2238 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"Mex_1p1918 adenine-specific DNA methyltransferase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"Mex_1p3758 D12 class N6 adenine-specific DNA methyltransferase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"Mex_1p0066 vsr; very-short-patch-repair endonuclease\tK07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]"
					},
					{
						"name":"Mex_2p0791 vsr; DNA mismatch endonuclease vsr\tK07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"Mex_1p0008 recD; Helicase\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"Mex_2p0511 putative Helicase, RecD\/TraA family\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"Mex_2p0584 putative Helicase, RecD\/TraA family\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"Mex_1p2721 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"Mex_1p0739 ruvA; Holliday junction ATP-dependent DNA helicase ruvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"Mex_1p5225 ruvB; Holliday junction ATP-dependent DNA helicase\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0995 ruvB; ATP-dependent DNA helicase, component of RuvABC resolvasome\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"Mex_1p0737 ruvC; RuvC; Holliday junction nuclease\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					},
					{
						"name":"Mex_1p3972 Hypothetical protein\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"Mex_1p1178 priA; Primosome factor N' (replication factor Y)\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0530 putative Exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
					},
					{
						"name":"Mex_1p0195 sbcC; Nuclease sbcCD subunit C\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"Mex_1p0194 sbcD; ATP-dependent dsDNA exonuclease\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"Mex_1p2721 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"Mex_1p4318 radA; DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"Mex_1p0003 recF; putative RecF protein\tK03629 recF; DNA replication and repair protein RecF"
					},
					{
						"name":"Mex_1p4550 recG; DNA helicase, ATP-dependent resolution of Holliday junctions, branch migration\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					},
					{
						"name":"Mex_1p2959 recJ; putative single-strand DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					},
					{
						"name":"Mex_2p0507 Single-stranded-DNA-specific exonuclease protein\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					},
					{
						"name":"Mex_1p0821 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
					},
					{
						"name":"Mex_1p1532 recR; recombination protein recR\tK06187 recR; recombination protein RecR"
					},
					{
						"name":"Mex_1p3158 recN; DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
					},
					{
						"name":"Mex_1p0739 ruvA; Holliday junction ATP-dependent DNA helicase ruvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"Mex_1p5225 ruvB; Holliday junction ATP-dependent DNA helicase\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"Mex_2p0995 ruvB; ATP-dependent DNA helicase, component of RuvABC resolvasome\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"Mex_1p0737 ruvC; RuvC; Holliday junction nuclease\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins",
					"children":[
					{
						"name":"Mex_1p4883 putative helicase-exonuclease type V protein family\tK16898 addA; ATP-dependent helicase\/nuclease subunit A [EC:5.6.2.4 3.1.-.-]"
					},
					{
						"name":"Mex_1p4882 conserved hypothetical protein\tK16899 addB; ATP-dependent helicase\/nuclease subunit B [EC:5.6.2.4 3.1.-.-]"
					}
					]
				},
				{
					"name":"Other HR factor",
					"children":[
					{
						"name":"Mex_1p3022 putative helicase domain protein with DEAD\/DEAH motif\tK19789 radD; DNA repair protein RadD"
					}
					]
				},
				{
					"name":"Archaeal homologous recombinant proteins",
					"children":[
					{
						"name":"Mex_1p0195 sbcC; Nuclease sbcCD subunit C\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"Mex_1p0194 sbcD; ATP-dependent dsDNA exonuclease\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					},
					{
						"name":"Mex_1p4857 yjgR; putative enzyme with nucleoside triphosphate hydrolase domain\tK06915 herA; DNA double-strand break repair helicase HerA and related ATPase"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"Mex_1p5016 gyrA; DNA gyrase, subunit A (type II topoisomerase)\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"Mex_2p0574 gyrA; DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"Mex_1p2546 gyrB; DNA gyrase, subunit B (type II topoisomerase)\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"Mex_2p0578 gyrB; DNA gyrase, subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"Mex_1p1949 putative DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						},
						{
							"name":"Mex_1p3523 topA; DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						},
						{
							"name":"Mex_2p0524 putative DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						}
						]
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway",
						"children":[
						{
							"name":"Mex_1p2959 recJ; putative single-strand DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
						},
						{
							"name":"Mex_2p0507 Single-stranded-DNA-specific exonuclease protein\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
						},
						{
							"name":"Mex_1p0821 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
						},
						{
							"name":"Mex_1p1532 recR; recombination protein recR\tK06187 recR; recombination protein RecR"
						},
						{
							"name":"Mex_1p5091 dnlJ; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						},
						{
							"name":"Mex_2p0992 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						}
						]
					},
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"Mex_1p2037 ihfA; integration host factor (IHF), DNA-binding protein, alpha subunit\tK04764 ihfA; integration host factor subunit alpha"
						},
						{
							"name":"Mex_2p0757 Putative integration host factor\tK04764 ihfA; integration host factor subunit alpha"
						},
						{
							"name":"Mex_1p0052 ihfB; integration host factor (IHF), beta subunit, site-specific recombination\tK05788 ihfB; integration host factor subunit beta"
						},
						{
							"name":"Mex_p20033 integration host factor (IHF) like DNA-binding protein\tK05788 ihfB; integration host factor subunit beta"
						}
						]
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"Mex_2p0530 putative Exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
						},
						{
							"name":"Mex_1p0005 recQ; ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"Mex_2p0075 ATP-dependent DNA helicase (fragment)\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"Mex_2p0238 ATP-dependent DNA helicase (fragment)\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"Mex_1p0099 Excinuclease ABC, A subunit\tK03701 uvrA; excinuclease ABC subunit A"
						},
						{
							"name":"Mex_1p4267 uvrA; DNA excision repair enzyme subunit, with UvrBC\tK03701 uvrA; excinuclease ABC subunit A"
						},
						{
							"name":"Mex_1p4445 uvrB; UvrABC system protein B (UvrB protein) (Excinuclease ABC subunit B)\tK03702 uvrB; excinuclease ABC subunit B"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"Mex_1p5172 dinB; DNA polymerase IV (Pol IV)\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"Mex_2p0850 dinB; DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"Mex_2p0643 umuC; component of DNA polymerase V, subunit C\tK03502 umuC; DNA polymerase V"
				},
				{
					"name":"Mex_2p0644 umuD; component of DNA polymerase V, subunit D\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				}
				]
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"Mex_1p2721 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"Mex_1p5132 lexA; SOS response transcriptional repressor, lexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"Mex_1p3158 recN; DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"Mex_1p5023 putative damage-inducible mutagenesis protein (ImuA-like)\tK14160 imuA; protein ImuA"
				},
				{
					"name":"Mex_1p5024 putative damage-inducible mutagenesis protein (ImuB-like)\tK14161 imuB; protein ImuB"
				},
				{
					"name":"Mex_1p5025 dnaE; error-prone DNA polymerase, DNA polymerase III, alpha subunit\tK14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]"
				},
				{
					"name":"Mex_1p2238 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Mex_1p2304 conserved hypothetical protein\tK03565 recX; regulatory protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases",
				"children":[
				{
					"name":"Mex_2p0618 Hypothetical protein\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"Mex_1p1571 ATP-dependent helicase\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				},
				{
					"name":"Mex_1p2592 DEAD\/DEAH box helicase domain protein\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				},
				{
					"name":"Mex_1p3367 ATP-dependent DNA helicase\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				},
				{
					"name":"Mex_2p1064 putative DEAD\/DEAH box helicase domain protein\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"Mex_1p0202 putative mutator MutT protein precursor; putative NTP pyrophosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Mex_1p1386 putative Nudix hydrolase family protein, putative pyrophosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Mex_1p4696 putative GDP-mannose mannosyl hydrolase (nudD)\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Mex_1p1415 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"Mex_1p0872 nrd; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, large subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Mex_2p0021 nrd; ribonucleoside-diphosphate reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}