{
	"name":"mei03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"Msip34_1780 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases",
				"children":[
				{
					"name":"Msip34_0005 protein of unknown function RIO1\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"Msip34_1438 Exonuclease RNase T and DNA polymerase III\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"Msip34_1779 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Msip34_0514 GTP-binding protein Obg\/CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"Msip34_0075 transcriptional regulator, TraR\/DksA family\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"Msip34_0890 transcriptional regulator, TraR\/DksA family\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"Msip34_0069 NusA antitermination factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"Msip34_2256 NusB antitermination factor\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"Msip34_0289 NusG antitermination factor\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"Msip34_1136 pseudouridine synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"Msip34_0576 dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"Msip34_0187 sun protein\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"Msip34_0224 Fmu (Sun) domain protein\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"Msip34_1920 methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"Msip34_0480 protein of unknown function DUF558\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Msip34_2825 methyltransferase GidB\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Msip34_0452 S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"Msip34_1396 Uroporphyrin-III C\/tetrapyrrole (Corrin\/Porphyrin) methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Msip34_2310 Uroporphyrin-III C\/tetrapyrrole (Corrin\/Porphyrin) methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"Msip34_1721 RNA methyltransferase, TrmH family, group 3\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"Msip34_1874 ribosomal RNA methyltransferase RrmJ\/FtsJ\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"Msip34_2175 protein of unknown function DUF163\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"Msip34_1000 protein of unknown function DUF519\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"Msip34_0894 putative RNA methylase\tK25137 rlmL; 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.173]"
				},
				{
					"name":"Msip34_1719 radical SAM enzyme, Cfr family\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"Msip34_0962 RNA methyltransferase, TrmA family\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"Msip34_0925 pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"Msip34_1265 pseudouridine synthase, RluA family\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"Msip34_1708 pseudouridine synthase, RluA family\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Msip34_0590 pseudouridine synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"Msip34_2616 RNA-binding S4 domain protein\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"Msip34_2285 ribosomal-protein-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"Msip34_2393 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"Msip34_1701 MiaB-like tRNA modifying enzyme YliG\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"Msip34_0022 ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"Msip34_0929 modification methylase, HemK family\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"Msip34_1805 Cupin 4 family protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"Msip34_1780 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"Msip34_1264 ribonuclease, Rne\/Rng family\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"Msip34_0619 ribonuclease, Rne\/Rng family\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"Msip34_0629 Holliday junction resolvase YqgF\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases"
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"Msip34_1779 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Msip34_1441 ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"Msip34_1710 small GTP-binding protein\tK03977 engA; GTPase"
			},
			{
				"name":"Msip34_0514 GTP-binding protein Obg\/CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"Msip34_1067 GTP-binding protein HSR1-related\tK14540 rbgA; ribosome biogenesis GTPase A"
			},
			{
				"name":"Msip34_0004 GTP-binding proten HflX\tK03665 hflX; GTPase"
			},
			{
				"name":"Msip34_1691 GTP-binding proten HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"Msip34_0379 SUA5\/yciO\/yrdC domain protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"Msip34_0053 (p)ppGpp synthetase I, SpoT\/RelA\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"Msip34_0071 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"Msip34_0068 protein of unknown function DUF150\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"Msip34_0143 conserved hypothetical protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"Msip34_2174 iojap-like protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"Msip34_2121 protein of unknown function UPF0054\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"Msip34_1875 protein of unknown function UPF0044\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"Msip34_2182 protein of unknown function DUF615\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"Msip34_0201 sigma 54 modulation protein\/ribosomal protein S30EA\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"Msip34_2014 GTP-binding protein YchF\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"Msip34_1391 protein of unknown function DUF177\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}