{
	"name":"meme04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"HYG87_09335 eno; phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"HYG87_04295 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"HYG87_10260 peroxiredoxin\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]"
			},
			{
				"name":"HYG87_04215 tuf; translation elongation factor EF-1 subunit alpha\tK03231 EEF1A; elongation factor 1-alpha"
			},
			{
				"name":"HYG87_05045 GTP-binding protein\tK03231 EEF1A; elongation factor 1-alpha"
			},
			{
				"name":"HYG87_04220 elongation factor EF-2\tK03234 EEF2; elongation factor 2"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"HYG87_03300 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_09955 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_05645 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"HYG87_07570 fen; flap endonuclease-1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
			},
			{
				"name":"HYG87_10370 guaB; IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"HYG87_00015 30S ribosomal protein S27ae\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			},
			{
				"name":"HYG87_07590 CDC48 family AAA ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells"
		},
		{
			"name":"Exosomal proteins of hepatic cells"
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"HYG87_07295 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"HYG87_03300 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_09955 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_03280 thiolase domain-containing protein\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"HYG87_07680 AAA family ATPase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"HYG87_09250 adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"HYG87_05810 purine phosphoribosyltransferase family protein\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"HYG87_00010 argH; argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"HYG87_05425 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"HYG87_07195 glnA; type I glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"HYG87_03020 hemB; porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"HYG87_08390 4a-hydroxytetrahydrobiopterin dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"HYG87_03945 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"HYG87_07295 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"HYG87_07625 NAD(P)\/FAD-dependent oxidoreductase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"HYG87_10370 guaB; IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"HYG87_05645 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"HYG87_03300 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_09955 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"HYG87_03300 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_09955 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_05645 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"HYG87_04300 tpiA; triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"HYG87_00015 30S ribosomal protein S27ae\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"HYG87_03300 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_09955 TCP-1\/cpn60 chaperonin family protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"HYG87_04300 tpiA; triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"HYG87_04300 tpiA; triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}