{
	"name":"mgl04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"MGL_3832 hypothetical protein\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"MGL_3469 hypothetical protein\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			},
			{
				"name":"MGL_3529 hypothetical protein\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"MGL_3930 hypothetical protein\tK12158 NEDD8; ubiquitin-like protein Nedd8"
			},
			{
				"name":"MGL_0596 hypothetical protein\tK02983 RP-S30e; small subunit ribosomal protein S30e"
			},
			{
				"name":"MGL_2013 hypothetical protein\tK08341 GABARAP; GABA(A) receptor-associated protein"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"MGL_2996 hypothetical protein\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"MGL_0434 hypothetical protein\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"MGL_2623 hypothetical protein\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"MGL_0174 hypothetical protein\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"MGL_1219 hypothetical protein\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"MGL_0659 hypothetical protein\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"MGL_1403 hypothetical protein\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"MGL_3547 hypothetical protein\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"MGL_0967 hypothetical protein\tK10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]"
			},
			{
				"name":"MGL_0182 hypothetical protein\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"MGL_0836 hypothetical protein\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"MGL_0089 hypothetical protein\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"MGL_0325 hypothetical protein\tK10689 PEX4; peroxin-4 [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"MGL_0041 hypothetical protein\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"MGL_3956 hypothetical protein\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"MGL_3297 hypothetical protein\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"MGL_2710 hypothetical protein\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"MGL_3533 hypothetical protein\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"MGL_0607 hypothetical protein\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"MGL_0055 hypothetical protein\tK10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]"
			},
			{
				"name":"MGL_1896 hypothetical protein\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins"
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"MGL_3731 hypothetical protein\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"MGL_2428 hypothetical protein\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"MGL_2429 hypothetical protein\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"MGL_1953 hypothetical protein\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"MGL_1641 hypothetical protein\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins"
			},
			{
				"name":"SINA (Seven in absentia) proteins"
			},
			{
				"name":"Ligand of Numb proteins"
			},
			{
				"name":"March proteins"
			},
			{
				"name":"MDM2\/MDM4 proteins"
			},
			{
				"name":"NFX1 proteins"
			},
			{
				"name":"Pellino proteins"
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"MGL_2667 hypothetical protein\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"MGL_1762 hypothetical protein\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"MGL_0249 hypothetical protein\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"MGL_2946 hypothetical protein\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins"
			},
			{
				"name":"TRIM\/RBCC proteins"
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"MGL_2526 hypothetical protein\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"MGL_2893 hypothetical protein\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"MGL_0196 hypothetical protein\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"MGL_0372 hypothetical protein\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"MGL_0403 hypothetical protein\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"MGL_2236 hypothetical protein\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"MGL_3061 hypothetical protein\tK11984 SART1; U4\/U6.U5 tri-snRNP-associated protein 1"
				},
				{
					"name":"MGL_1004 hypothetical protein\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"MGL_1081 hypothetical protein\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"MGL_2028 hypothetical protein\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"MGL_0228 hypothetical protein\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"MGL_1361 hypothetical protein\tK23787 DMA1_2; E3 ubiquitin-protein ligase DMA1\/2 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"MGL_3527 hypothetical protein\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"MGL_0065 hypothetical protein\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"MGL_3448 hypothetical protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"MGL_2715 hypothetical protein\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"MGL_3474 hypothetical protein\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"MGL_2979 hypothetical protein\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"MGL_1058 hypothetical protein\tK10259 MET30; F-box and WD-40 domain protein MET30"
					},
					{
						"name":"MGL_1013 hypothetical protein\tK03361 CDC4; F-box and WD-40 domain protein CDC4"
					},
					{
						"name":"MGL_3466 hypothetical protein\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"MGL_1408 hypothetical protein\tK03360 GRR1; F-box and leucine-rich repeat protein GRR1"
					},
					{
						"name":"MGL_3893 hypothetical protein\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"MGL_3633 hypothetical protein\tK10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]"
					},
					{
						"name":"MGL_3099 hypothetical protein\tK15071 RCY1; recyclin-1"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"MGL_0168 hypothetical protein\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"MGL_2653 hypothetical protein\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)"
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"MGL_0054 hypothetical protein\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"MGL_2753 hypothetical protein\tK10610 DDB1; DNA damage-binding protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"MGL_4123 hypothetical protein\tK11790 DTL; denticleless"
					},
					{
						"name":"MGL_2741 hypothetical protein\tK11800 DCAF5; DDB1- and CUL4-associated factor 5"
					},
					{
						"name":"MGL_2134 hypothetical protein\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"MGL_2949 hypothetical protein\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"MGL_1105 hypothetical protein\tK24752 WDR70; WD repeat-containing protein 70"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"MGL_0168 hypothetical protein\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"MGL_3474 hypothetical protein\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_0788 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"MGL_3177 hypothetical protein\tK03358 APC11; anaphase-promoting complex subunit 11"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"MGL_3361 hypothetical protein\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"MGL_0523 hypothetical protein\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"MGL_3847 hypothetical protein\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"MGL_0575 hypothetical protein\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"MGL_1894 hypothetical protein\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"MGL_2658 hypothetical protein\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"MGL_3588 hypothetical protein\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"MGL_2264 hypothetical protein\tK03357 APC10; anaphase-promoting complex subunit 10"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"MGL_2937 hypothetical protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
				},
				{
					"name":"MGL_2183 hypothetical protein\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex"
			},
			{
				"name":"LUBAC complex"
			},
			{
				"name":"CTLH complex"
			},
			{
				"name":"ERAD complex"
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex"
			},
			{
				"name":"STUB1-CHIC2  complex"
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"MGL_2542 hypothetical protein\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"MGL_1812 hypothetical protein\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"MGL_3516 hypothetical protein\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_1761 hypothetical protein\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_3966 hypothetical protein\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_3838 hypothetical protein\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_2823 hypothetical protein\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_2346 hypothetical protein\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_0927 hypothetical protein\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_1217 hypothetical protein\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_4048 hypothetical protein\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_1437 hypothetical protein\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_2629 hypothetical protein\tK11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"MGL_3846 hypothetical protein\tK13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"MGL_4250 hypothetical protein\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD",
				"children":[
				{
					"name":"MGL_0737 hypothetical protein\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				}
				]
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"MGL_3759 hypothetical protein\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"MGL_0266 hypothetical protein\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				},
				{
					"name":"MGL_4133 hypothetical protein\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"PPPDE"
			},
			{
				"name":"ZUFSP"
			},
			{
				"name":"BRISC complex"
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"MGL_3160 hypothetical protein\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"MGL_1812 hypothetical protein\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"MGL_3090 hypothetical protein\tK12175 GPS1; COP9 signalosome complex subunit 1"
				},
				{
					"name":"MGL_0709 hypothetical protein\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"MGL_3632 hypothetical protein\tK12177 COPS3; COP9 signalosome complex subunit 3"
				},
				{
					"name":"MGL_2583 hypothetical protein\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"MGL_0417 hypothetical protein\tK24364 CSN12; COP9 signalosome complex subunit 12"
				}
				]
			}
			]
		}
		]
	}
	]
}