{
	"name":"mgm04121",
	"children":[
	{
		"name":"Ubiquitins and Ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins"
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)"
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme"
		},
		{
			"name":"UBL-activating enzymes"
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes"
		},
		{
			"name":"UBL-conjugating enzymes"
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3"
		},
		{
			"name":"U-box type E3"
		},
		{
			"name":"single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 protein"
			},
			{
				"name":"CBL protein"
			},
			{
				"name":"SINA (Seven in absentia) proteins"
			},
			{
				"name":"March proteins"
			},
			{
				"name":"Pellino proteins"
			},
			{
				"name":"RBR proteins"
			},
			{
				"name":"TRAF proteins"
			},
			{
				"name":"TRIM\/RBCC proteins"
			},
			{
				"name":"UBR box proteins"
			},
			{
				"name":"Other single Ring-finger type E3"
			}
			]
		},
		{
			"name":"UBL E3 ligases"
		},
		{
			"name":"multi subunit Ring-finger type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"adaptor protein"
				},
				{
					"name":"target recognizing subunit (F-box)"
				}
				]
			},
			{
				"name":"ECV complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"adoptor protein"
				},
				{
					"name":"target recognizing subunit (VHL box)"
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"target recognizing subunit (BTB)"
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"adoptor protein"
				},
				{
					"name":"target recognizing subunit (DCAF)"
				}
				]
			},
			{
				"name":"ECS complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"adoptor protein"
				},
				{
					"name":"target recognizing subunit (SOCS box)"
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"adaptor protein"
				},
				{
					"name":"target recognizing subunit"
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"target recognizing subunit"
				},
				{
					"name":"other subunits"
				}
				]
			},
			{
				"name":"BRCC complex"
			},
			{
				"name":"KPC complex"
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH"
			},
			{
				"name":"UBP\/USP"
			},
			{
				"name":"OTU"
			},
			{
				"name":"MJD"
			},
			{
				"name":"JAMM"
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"COP9 signalosome (CSN) complex"
			}
			]
		}
		]
	},
	{
		"name":"Proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"alpha type subunits"
			},
			{
				"name":"beta type subunits"
			}
			]
		},
		{
			"name":"PA700 (19S proteasome)",
			"children":[
			{
				"name":"ATPase subunits"
			},
			{
				"name":"non-ATPase subunits"
			}
			]
		},
		{
			"name":"PA28 (11S REG)"
		},
		{
			"name":"PA200"
		},
		{
			"name":"PI31"
		},
		{
			"name":"Prokaryotic proteasome",
			"children":[
			{
				"name":"Core particles (20S proteasome)"
			},
			{
				"name":"Bacterial regulatory subunits"
			},
			{
				"name":"Archaeal regulatory subunit"
			}
			]
		},
		{
			"name":"Assembling factors",
			"children":[
			{
				"name":"Assembling chaperones"
			},
			{
				"name":"Other assembling factors",
				"children":[
				{
					"name":"Mmc1_1694 heat shock protein 90; K04079 molecular chaperone HtpG"
				}
				]
			}
			]
		},
		{
			"name":"Proteasome interacting proteins (PIPs)",
			"children":[
			{
				"name":"UBL-UBA shuttle proteins"
			},
			{
				"name":"Other PIPs"
			}
			]
		}
		]
	},
	{
		"name":"ESCRTs",
		"children":[
		{
			"name":"ESCRT-0"
		},
		{
			"name":"ESCRT-1"
		},
		{
			"name":"ESCRT-2"
		},
		{
			"name":"ESCRT-3"
		},
		{
			"name":"Accessory components"
		}
		]
	}
	]
}