{
	"name":"mict04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"FIU95_15055 htpG; Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"FIU95_05965 fda1; Fructose-bisphosphate aldolase class 1\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
			},
			{
				"name":"FIU95_14890 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"FIU95_08795 gap1; Glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"FIU95_16155 gap3; Glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"FIU95_19535 pgk; Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"FIU95_16150 pykA1; Pyruvate kinase II\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"FIU95_20070 pykA2; Pyruvate kinase II\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"FIU95_06190 ppiA; Peptidyl-prolyl cis-trans isomerase A precursor\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
			},
			{
				"name":"FIU95_00265 Membrane dipeptidase (Peptidase family M19)\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"FIU95_10550 Membrane dipeptidase (Peptidase family M19)\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"FIU95_15065 tsaA2; putative peroxiredoxin\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]"
			},
			{
				"name":"FIU95_00455 yqiK; Inner membrane protein YqiK\tK07192 FLOT; flotillin"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"FIU95_05500 groL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"FIU95_17240 dnaK; Chaperone protein DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"FIU95_04555 pgi; Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"FIU95_17575 ptpA3; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"FIU95_05825 gnl1; Gluconolactonase precursor\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
			},
			{
				"name":"FIU95_11080 gnl2; Gluconolactonase precursor\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
			},
			{
				"name":"FIU95_06165 guaB; Inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"FIU95_02300 tuf1; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"FIU95_02365 tuf2; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"FIU95_05980 HIT-like protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			},
			{
				"name":"FIU95_13120 HIT-like protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells",
			"children":[
			{
				"name":"FIU95_17575 ptpA3; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			}
			]
		},
		{
			"name":"Exosomal proteins of hepatic cells"
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"FIU95_07560 fadK; Short-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_08760 lcfB2; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_12015 lcfB3; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_13200 fadD; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_16450 Long-chain-fatty-acid--CoA ligase FadD15\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_18575 menE; 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"FIU95_05500 groL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"FIU95_09600 fadA1; 3-ketoacyl-CoA thiolase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"FIU95_15640 thlA; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"FIU95_19260 fadA3; Putative acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"FIU95_05705 Angiotensin-converting enzyme\tK01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]"
			},
			{
				"name":"FIU95_20325 ahcY; Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"FIU95_06750 adk; Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"FIU95_00850 argH1; Argininosuccinate lyase 1\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"FIU95_05370 argG; Argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"FIU95_05960 glpK; Glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"FIU95_07040 puuA1; Gamma-glutamylputrescine synthetase PuuA\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"FIU95_09125 puuA2; Gamma-glutamylputrescine synthetase PuuA\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"FIU95_16660 glnA1; Glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"FIU95_19870 glnA2; Glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"FIU95_04555 pgi; Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"FIU95_02145 hemB; Delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"FIU95_00490 hpd; 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"FIU95_05780 Putative pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"FIU95_20420 phoA1; Alkaline phosphatase precursor\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"FIU95_20425 phoA2; Alkaline phosphatase precursor\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"FIU95_19480 serA; D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"FIU95_02070 purH; Bifunctional purine biosynthesis protein PurH\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"FIU95_07560 fadK; Short-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_08760 lcfB2; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_12015 lcfB3; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_13200 fadD; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_16450 Long-chain-fatty-acid--CoA ligase FadD15\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_18575 menE; 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"FIU95_15260 lpd; Dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"FIU95_10445 etfA; Electron transfer flavoprotein subunit alpha\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"FIU95_16170 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"FIU95_06165 guaB; Inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"FIU95_17240 dnaK; Chaperone protein DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"FIU95_05500 groL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"FIU95_02300 tuf1; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"FIU95_02365 tuf2; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"FIU95_05500 groL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"FIU95_04555 pgi; Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"FIU95_17575 ptpA3; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"FIU95_16170 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"FIU95_17240 dnaK; Chaperone protein DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"FIU95_16990 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"FIU95_02300 tuf1; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"FIU95_02365 tuf2; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"FIU95_05500 groL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"FIU95_16170 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"FIU95_16990 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"FIU95_16990 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells",
			"children":[
			{
				"name":"FIU95_00385 blc1; Outer membrane lipoprotein Blc precursor\tK03098 APOD; apolipoprotein D and lipocalin family protein"
			},
			{
				"name":"FIU95_10285 blc2; Outer membrane lipoprotein Blc precursor\tK03098 APOD; apolipoprotein D and lipocalin family protein"
			}
			]
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}