{
	"name":"mmi03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"MMAR_3921 conserved hypothetical phage DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family",
				"children":[
				{
					"name":"MMAR_1063 transcriptional regulatory protein\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"MMAR_4081 alkA; Ada regulatory protein AlkA\tK13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response \/ DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
				}
				]
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"MMAR_2756 oxyR; hydrogen peroxide-inducible genes activator, OxyR\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				}
				]
			},
			{
				"name":"DeoR family"
			},
			{
				"name":"LacI family"
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"MMAR_0304 transcriptional regulatory protein (probably GntR-family)\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"MMAR_2560 transcriptional regulatory protein (probably GntR-family)\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"MMAR_4842 regulatory protein\tK03710 K03710; GntR family transcriptional regulator"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"MMAR_0287 transcriptional regulatory protein\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"MMAR_0355 transcriptional regulatory protein (possibly TetR-family)\tK16138 uidR; TetR\/AcrR family transcriptional regulator, repressor for uid operon"
				},
				{
					"name":"MMAR_1026 transcriptional regulator (TetR family)\tK18294 nfxB; TetR\/AcrR family transcriptional regulator, mexCD-oprJ operon repressor"
				},
				{
					"name":"MMAR_2831 transcriptional regulator\tK18294 nfxB; TetR\/AcrR family transcriptional regulator, mexCD-oprJ operon repressor"
				},
				{
					"name":"MMAR_2833 transcriptional regulator (TetR family)\tK18294 nfxB; TetR\/AcrR family transcriptional regulator, mexCD-oprJ operon repressor"
				},
				{
					"name":"MMAR_3762 transcriptional regulatory protein (AcrR family)\tK21961 ethR; TetR\/AcrR family transcriptional regulator, ethionamide resistance regulator"
				},
				{
					"name":"MMAR_5405 ethR; transcriptional regulatory repressor protein (TetR-family) EthR\tK21961 ethR; TetR\/AcrR family transcriptional regulator, ethionamide resistance regulator"
				},
				{
					"name":"MMAR_2281 transcriptional regulatory protein\tK21962 acnR; TetR\/AcrR family transcriptional regulator, transcriptional repressor of aconitase"
				},
				{
					"name":"MMAR_0141 transcriptional regulatory protein (probably TetR-family)\tK22107 kstR; TetR\/AcrR family transcriptional regulator, cholesterol catabolism regulator"
				},
				{
					"name":"MMAR_0929 TetR-family transcriptional regulator\tK22107 kstR; TetR\/AcrR family transcriptional regulator, cholesterol catabolism regulator"
				},
				{
					"name":"MMAR_4839 transcriptional regulatory protein (TetR-family)\tK22107 kstR; TetR\/AcrR family transcriptional regulator, cholesterol catabolism regulator"
				},
				{
					"name":"MMAR_5069 transcriptional regulatory protein (TetR-family)\tK22107 kstR; TetR\/AcrR family transcriptional regulator, cholesterol catabolism regulator"
				},
				{
					"name":"MMAR_5046 transcriptional regulatory protein (probably TetR-family)\tK22108 kstR2; TetR\/AcrR family transcriptional regulator, cholesterol catabolism regulator"
				},
				{
					"name":"MMAR_1019 transcriptional regulator\tK24699 mftR; TetR\/AcrR family transcriptional regulator, regulator of mycofactocin system"
				},
				{
					"name":"MMAR_2873 mce3R; transcriptional repressor (probably TetR-family) Mce3R\tK27107 mce3R; TetR\/AcrR family transcriptional regulator, mce3 operon repressor"
				},
				{
					"name":"MMAR_1142 transcriptional regulator\tK22295 K22295; TetR\/AcrR family transcriptional regulator, repressor for neighboring sulfatase"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"MMAR_3557 transcriptional regulatory protein (probably Lrp\/AsnC-family)\tK03718 asnC; Lrp\/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA"
				},
				{
					"name":"MMAR_1242 transcriptional regulatory protein (probably AsnC-family)\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"MMAR_4163 conserved hypothetical transcriptional regulator (Lrp family)\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				}
				]
			},
			{
				"name":"LuxR family",
				"children":[
				{
					"name":"MMAR_2876 conserved hypothetical regulatory protein\tK21685 ramA; LuxR family transcriptional regulator, regulator of acetate metabolism"
				}
				]
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"MMAR_0145 transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"MMAR_0640 hspR; heat shock protein transcriptional repressor HspR (MerR family)\tK13640 hspR; MerR family transcriptional regulator, heat shock protein HspR"
				},
				{
					"name":"MMAR_2990 hspR_2; heat shock protein transcriptional repressor HspR_2\tK13640 hspR; MerR family transcriptional regulator, heat shock protein HspR"
				},
				{
					"name":"MMAR_0009 transcriptional regulator\tK21744 tipA; MerR family transcriptional regulator, thiopeptide resistance regulator"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"MMAR_1874 ferric uptake regulation protein FurB-like protein\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"MMAR_3669 zur; Zinc uptake regulation protein Zur\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"MMAR_2915 furA; ferric uptake regulation protein FurA\tK22297 furA; Fur family transcriptional regulator, stress-responsive regulator"
				}
				]
			},
			{
				"name":"IclR family"
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"MMAR_5164 conserved regulatory protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"MMAR_1621 transcriptional regulatory protein\tK21884 cmr; CRP\/FNR family transcriptional regulator, cAMP and macrophage regulator"
				}
				]
			},
			{
				"name":"Rrf2 family"
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"MMAR_2056 transcriptional regulatory protein (probably ArsR-family)\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"MMAR_2058 transcriptional regulatory protein (probably ArsR-family)\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"MMAR_4852 ArsR-family transcriptional regulator\tK22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor"
				},
				{
					"name":"MMAR_3668 transcriptional regulatory protein (probably ArsR-family)\tK22298 smtB; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family",
				"children":[
				{
					"name":"MMAR_1378 transcriptional regulatory protein\tK21686 prpR; XRE family transcriptional regulator, fatty acid utilization regulator"
				},
				{
					"name":"MMAR_0790 transcriptional regulatory protein\tK07110 ramB; XRE family transcriptional regulator, fatty acid utilization regulator"
				},
				{
					"name":"MMAR_1970 transcriptional regulatory protein\tK27043 clgR; XRE family transcriptional regulator, stress-response regulator"
				}
				]
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"MMAR_2002 ideR; iron-dependent repressor and activator IdeR\tK26252 dtxR; DtxR family transcriptional regulator, iron-dependent repressor"
				},
				{
					"name":"MMAR_1920 sirR; transcriptional repressor SirR\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"MMAR_2720 transcriptional regulatory protein\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"MMAR_1257 birA; bifunctional protein BirA\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"MMAR_2965 nadR; predicted ATPase\/kinase, NadR\tK06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]"
				},
				{
					"name":"MMAR_0024 plasmid maintenance system antidote protein\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA"
				},
				{
					"name":"MMAR_3604 plasmid maintenance system antidote protein\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA"
				},
				{
					"name":"MMAR_5399 conserved protein\tK27097 espR; ESX-1-secreted protein regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"MMAR_1132 whiB3; WhiB-like regulatory protein, WhiB3\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"MMAR_1282 whiB2; transcriptional regulatory protein Whib-like WhiB2\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"MMAR_1338 whiB1; transcriptional regulatory protein Whib-like WhiB1\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"MMAR_5170 whiB4; transcriptional regulatory protein Whib-like WhiB4\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"MMAR_0041 whiB5; transcriptional regulatory protein (Whib-like), WhiB5\tK18956 whiB5; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"MMAR_5437 conserved hypothetical protein\tK18957 whiB6; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"MMAR_1365 whiB7; transcriptional regulatory protein Whib-like WhiB7\tK18958 whiB7; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"MMAR_0433 conserved hypothetical protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"MMAR_1412 conserved hypothetical protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"MMAR_1447 conserved hypothetical protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"MMAR_2538 conserved hypothetical protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"MMAR_4874 conserved hypothetical protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"MMAR_0930 embR_2; transcriptional regulatory protein EmbR_2\tK22894 embR; SARP family transcriptional regulator, regulator of embCAB operon"
				},
				{
					"name":"MMAR_3545 embR_1; transcriptional regulatory protein EmbR_1\tK22894 embR; SARP family transcriptional regulator, regulator of embCAB operon"
				},
				{
					"name":"MMAR_4155 embR; transcriptional regulatory protein EmbR\tK22894 embR; SARP family transcriptional regulator, regulator of embCAB operon"
				},
				{
					"name":"MMAR_5481 parB; chromosome partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"MMAR_5083 conserved transcriptional regulatory protein\tK07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription"
				},
				{
					"name":"MMAR_2467 argR; arginine repressor ArgR\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"MMAR_3684 hrcA; heat shock protein transcriptional repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"MMAR_0229 conserved hypothetical protein\tK02616 paaX; phenylacetic acid degradation operon negative regulatory protein"
				},
				{
					"name":"MMAR_1003 conserved hypothetical regulatory protein\tK02616 paaX; phenylacetic acid degradation operon negative regulatory protein"
				},
				{
					"name":"MMAR_2194 pyrR; pyrimidine operon regulatory protein PyrR\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"MMAR_3794 transcriptional regulatory protein\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"MMAR_0053 conserved hypothetical protein\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"MMAR_1994 membrane-associated regulatory protein\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"MMAR_3203 conserved protein\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}