{
	"name":"mnt03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"21393912 DNA oxidative demethylase ALKBH2\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"21388198 DExH-box ATP-dependent RNA helicase DExH14\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"112093873 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"21393177 uracil-DNA glycosylase, mitochondrial\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"21410634 DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"21389023 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"21387359 methyl-CpG-binding domain protein 4-like protein isoform X1\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"21396550 N-glycosylase\/DNA lyase OGG1\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"21389840 putative DNA glycosylase At3g47830\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"21407453 endonuclease III homolog 1, chloroplastic isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"21407472 endonuclease III homolog 1, chloroplastic\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"21409321 DNA-(apurinic or apyrimidinic site) lyase 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"112095305 DNA polymerase delta catalytic subunit-like\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"21403563 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"21391287 DNA polymerase delta small subunit isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"21384550 uncharacterized protein LOC21384550 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"21386201 uncharacterized protein LOC21386201\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"21402579 DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"21392351 DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"21407831 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"21405152 DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"21385458 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"21404911 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"21405480 flap endonuclease 1 isoform X2\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"21403526 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"21402393 DNA-repair protein XRCC1\tK10803 XRCC1; DNA-repair protein XRCC1"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"21397935 tyrosyl-DNA phosphodiesterase 1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"21395270 transcription factor bHLH140\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"21387846 polynucleotide 3'-phosphatase ZDP isoform X1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"21388674 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"21393094 poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"21394370 poly [ADP-ribose] polymerase 2 isoform X2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"21405178 poly [ADP-ribose] polymerase 3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"21409815 DNA repair protein RAD4\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"21387912 ubiquitin receptor RAD23b\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"21392003 ubiquitin receptor RAD23d\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"21392005 ubiquitin receptor RAD23d\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"21410023 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"21404503 cullin-4\tK10609 CUL4; cullin 4"
						},
						{
							"name":"21393240 DNA damage-binding protein 1 isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"21404847 protein DAMAGED DNA-BINDING 2\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"21409999 uncharacterized protein LOC21409999\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"21395176 DNA repair protein RAD16 isoform X1\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"21409262 DNA-directed RNA polymerase II subunit 1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"21397658 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"21410072 DNA-directed RNA polymerases II, IV and V subunit 3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"21391700 DNA-directed RNA polymerase II subunit 4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"21400928 DNA-directed RNA polymerases IV and V subunit 4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"21387177 DNA-directed RNA polymerases II and IV subunit 5A\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"21388704 DNA-directed RNA polymerase V subunit 5A\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"21397676 DNA-directed RNA polymerases II, IV and V subunit 6A\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"21408022 DNA-directed RNA polymerase II subunit RPB7 isoform X1\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"21391178 DNA-directed RNA polymerases II and V subunit 8A\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"21403037 DNA-directed RNA polymerases II and V subunit 8A\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"112091205 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"21391118 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"21390428 DNA-directed RNA polymerase subunit 10-like protein\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"21387719 DNA-directed RNA polymerases II, IV and V subunit 11\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"21407405 DNA-directed RNA polymerases II, IV and V subunit 12\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"21410023 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"21404503 cullin-4\tK10609 CUL4; cullin 4"
						},
						{
							"name":"21393240 DNA damage-binding protein 1 isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"21385274 DNA excision repair protein ERCC-8\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"21389104 protein CHROMATIN REMODELING 8\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"21400547 UV-stimulated scaffold protein A homolog\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"21394685 transcription elongation factor 1 homolog isoform X1\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"21406990 general transcription and DNA repair factor IIH helicase subunit XPB1\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"21407776 general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"21406503 general transcription and DNA repair factor IIH subunit TFB1-1 isoform X1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"21397548 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"21403094 general transcription and DNA repair factor IIH subunit TFB4 isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"21395325 general transcription and DNA repair factor IIH subunit TFB2\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"21405974 general transcription and DNA repair factor IIH subunit TFB5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"21388634 cyclin-dependent kinase D-3\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"21409806 cyclin-H1-1\tK06634 CCNH; cyclin H"
					},
					{
						"name":"112094428 LOW QUALITY PROTEIN: uncharacterized protein LOC112094428\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"112090334 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21390529 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21410755 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21387928 replication protein A 32 kDa subunit A isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"21396051 replication protein A 32 kDa subunit B\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"112091086 replication protein A 14 kDa subunit B-like isoform X1\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"21387235 DNA excision repair protein ERCC-1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"21406159 DNA repair endonuclease UVH1 isoform X1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"112094535 DNA repair protein UVH3\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"21385694 flap endonuclease GEN-like 1\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"21403526 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"21408942 MMS19 nucleotide excision repair protein homolog\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"21398493 protein CIA1 isoform X2\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"21391265 protein AE7\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"21403194 protein AE7-like 1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"21389955 cullin-3A\tK03869 CUL3; cullin 3"
					},
					{
						"name":"21389956 cullin-3A\tK03869 CUL3; cullin 3"
					},
					{
						"name":"21408026 elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"21391852 uncharacterized protein LOC21391852\tK03873 ELOB; elongin-B"
					},
					{
						"name":"21391853 uncharacterized protein LOC21391853 isoform X1\tK03873 ELOB; elongin-B"
					},
					{
						"name":"112092188 uncharacterized protein LOC112092188\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"21405122 DNA mismatch repair protein MSH2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"21398856 DNA mismatch repair protein MSH3 isoform X1\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"21393076 DNA mismatch repair protein MSH6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					},
					{
						"name":"21403705 DNA mismatch repair protein MSH7\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"21387418 DNA mismatch repair protein MLH1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"21384726 DNA mismatch repair protein PMS1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"21390481 DNA mismatch repair protein MLH3 isoform X1\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"112095305 DNA polymerase delta catalytic subunit-like\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"21403563 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"21391287 DNA polymerase delta small subunit isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"21384550 uncharacterized protein LOC21384550 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"21386201 uncharacterized protein LOC21386201\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"21402579 DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"112090334 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21390529 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21410755 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21387928 replication protein A 32 kDa subunit A isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"21396051 replication protein A 32 kDa subunit B\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"112091086 replication protein A 14 kDa subunit B-like isoform X1\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"21394655 replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"21393850 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"21396557 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"21384034 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"21391900 uncharacterized protein LOC21391900\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"21392962 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"21396544 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"21406609 uncharacterized protein LOC21406609\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"21385458 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"21404911 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"21398708 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"21400401 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"21403526 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"21401884 LOW QUALITY PROTEIN: DNA damage-binding protein CMR1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"21401703 double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"21409478 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"21407869 nijmegen breakage syndrome 1 protein isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"21389392 BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"21398988 BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"21402696 protein BREAST CANCER SUSCEPTIBILITY 1 homolog\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"21402467 uncharacterized protein LOC21402467\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"21399130 BRISC and BRCA1-A complex member 2 isoform X2\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"21385482 lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"21407586 Fanconi anemia group J protein homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"21385497 BRCT domain-containing protein At4g02110\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					},
					{
						"name":"21396576 DNA topoisomerase 2-binding protein 1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"21401703 double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"21409478 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"21407869 nijmegen breakage syndrome 1 protein isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"21392813 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"21402505 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"21402505 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"21394463 DNA repair protein RAD51 homolog 2\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"21408273 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"21394137 DNA repair protein RAD51 homolog 4\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"21406900 DNA repair protein XRCC2 homolog isoform X5\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"21384392 DNA repair protein XRCC3 homolog\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"21395855 DNA repair RAD52-like protein 1, mitochondrial\tK26556 RAD52-1; DNA repair RAD52-like protein 1, mitochondrial"
					},
					{
						"name":"21388192 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"21384300 protein CHROMATIN REMODELING 35\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"21390362 SNF2 domain-containing protein CLASSY 1\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"21391485 protein CHROMATIN REMODELING 35\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"21406140 SNF2 domain-containing protein CLASSY 3\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"21407475 protein CHROMATIN REMODELING 35\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"21410039 protein CHROMATIN REMODELING 35\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"21410157 protein CHROMATIN REMODELING 25\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"21389528 mediator of RNA polymerase II transcription subunit 34 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"21404601 ATP-dependent DNA helicase Q-like 1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"21386406 ATP-dependent DNA helicase Q-like SIM isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"21386438 ATP-dependent DNA helicase Q-like SIM isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"21399756 ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"21410033 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"21390157 ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"21399756 ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"21410033 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"21388432 DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"21402836 DNA topoisomerase 3-beta\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"21393444 recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"21392348 recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"112090334 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21390529 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21410755 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"21387928 replication protein A 32 kDa subunit A isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"21396051 replication protein A 32 kDa subunit B\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"112091086 replication protein A 14 kDa subunit B-like isoform X1\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"21397186 serine\/threonine-protein phosphatase PP-X isozyme 2\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"21402634 serine\/threonine-protein phosphatase 4 regulatory subunit 2\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"21391121 serine\/threonine-protein phosphatase 4 regulatory subunit 3B\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"21396233 uncharacterized protein LOC21396233\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"21394565 AP-5 complex subunit mu\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"21385785 AP-5 complex subunit zeta-1 isoform X1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"21391328 structural maintenance of chromosomes protein 5\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"21390059 structural maintenance of chromosomes protein 6B\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"112091113 non-structural maintenance of chromosomes element 1 homolog isoform X1\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"21395388 E3 SUMO-protein ligase MMS21\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"21400996 non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"21390140 crossover junction endonuclease EME1B\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"21391975 crossover junction endonuclease MUS81 isoform X1\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"21394214 protein DELETION OF SUV3 SUPPRESSOR 1(I)\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"112095210 uncharacterized protein LOC112095210\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"21385039 structure-specific endonuclease subunit slx1 isoform X1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"21393980 uncharacterized protein LOC21393980\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"21389540 flap endonuclease GEN-like 1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"21398855 flap endonuclease GEN-like 2 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"21402259 flap endonuclease GEN-like 1 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"21400717 uncharacterized protein LOC21400717 isoform X1\tK19026 SPG11; spatacsin"
					},
					{
						"name":"21398035 uncharacterized protein LOC21398035 isoform X1\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"21392631 protein MRG1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"112092296 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"112094532 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"21394048 ATPase family AAA domain-containing protein FIGL1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"21394762 zinc finger SWIM domain-containing protein 7 isoform X1\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"21400366 uncharacterized protein C17orf53 homolog\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"21407190 probable DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"21387628 probable DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"21389828 heterogeneous nuclear ribonucleoprotein U-like protein 1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"21412777 uncharacterized protein LOC21412777\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"21387355 Werner Syndrome-like exonuclease\tK22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]"
					},
					{
						"name":"21401214 uncharacterized protein LOC21401214\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"21407367 alpha-N-acetylglucosaminidase\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"112091579 single-stranded DNA-binding protein WHY1, chloroplastic-like\tK26559 WHY1; single-stranded DNA-binding protein WHY1"
					},
					{
						"name":"21395849 single-stranded DNA-binding protein WHY2, mitochondrial\tK26561 WHY2; single-stranded DNA-binding protein WHY2"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"21395246 ATP-dependent DNA helicase 2 subunit KU70\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"21392932 ATP-dependent DNA helicase 2 subunit KU80 isoform X1\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"21401703 double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"21409478 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"21389092 DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"21399413 DNA repair protein XRCC4\tK10886 XRCC4; DNA-repair protein XRCC4"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"21388674 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"21395270 transcription factor bHLH140\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"112093891 uncharacterized protein LOC112093891\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"21383760 uncharacterized protein LOC21383760 isoform X1\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"21401023 uncharacterized protein LOC21401023 isoform X1\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"21395118 uncharacterized protein LOC21395118\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"21391158 E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"21386312 DEAD-box ATP-dependent RNA helicase FANCM\tK10896 FANCM; fanconi anemia group M protein"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"21387481 protein MHF1 homolog\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"21401899 protein MHF2 homolog\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"21403686 uncharacterized protein LOC21403686\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"21399756 ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"21410033 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"21388432 DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"21402836 DNA topoisomerase 3-beta\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"21393444 recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"21392348 recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"21400702 Fanconi anemia group D2 protein homolog\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"21390617 Fanconi anemia group I protein homolog isoform X1\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"21392813 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"21407586 Fanconi anemia group J protein homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"21399694 fanconi-associated nuclease 1 homolog isoform X1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"21402505 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"21408273 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"21391552 telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"21393541 WD repeat-containing protein 48 isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"21405849 phytochrome-associated serine\/threonine-protein phosphatase\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"21391441 serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"21408690 serine\/threonine-protein phosphatase 6 regulatory subunit 3\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					}
					]
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"21389826 telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"21398973 WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"21401884 LOW QUALITY PROTEIN: DNA damage-binding protein CMR1\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"21398924 uncharacterized protein LOC21398924\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"21387392 DNA polymerase eta isoform X1\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"21387200 DNA polymerase kappa\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"21409668 DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"21384891 DNA polymerase zeta catalytic subunit isoform X1\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				},
				{
					"name":"21390103 DNA polymerase zeta catalytic subunit\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"21391021 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"21403966 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"21391518 DNA repair protein RAD5B\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"21397255 DNA repair protein RAD5A\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"21388126 putative SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"112092748 ubiquitin-conjugating enzyme E2 variant 1B-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"112094333 ubiquitin-conjugating enzyme E2 variant 1A\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"21401811 ubiquitin-conjugating enzyme E2 variant 1D isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"21388301 ubiquitin-conjugating enzyme E2 36\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"21401631 ubiquitin-conjugating enzyme E2 36\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"21385458 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"21404911 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"21384715 uncharacterized protein LOC21384715\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"21394107 cell cycle checkpoint control protein RAD9A\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"21400754 uncharacterized protein LOC21400754 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"21409297 cell cycle checkpoint protein RAD17 isoform X1\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"21393850 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"21396557 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"21384034 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"21391900 uncharacterized protein LOC21391900\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"21392962 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"21396544 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"21406609 uncharacterized protein LOC21406609\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"21400754 uncharacterized protein LOC21400754 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"21394741 uncharacterized protein LOC21394741\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"21398106 TIMELESS-interacting protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"21391552 telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"21399286 uncharacterized protein LOC21399286 isoform X1\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"21389965 uncharacterized protein At2g39910\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"21397272 Golgi to ER traffic protein 4 homolog isoform X1\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"21383927 integrator complex subunit 3\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"21385687 integrator complex subunit 3\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"21403331 SOSS complex subunit B homolog\tK28889 NABP; SOSS complex subunit B"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"21389523 serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"21398136 LOW QUALITY PROTEIN: serine\/threonine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"112092168 14-3-3-like protein D isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"112092971 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"21384884 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"21389243 14-3-3-like protein C\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"21390084 14-3-3-like protein GF14 iota\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"21391912 14-3-3-like protein GF14 kappa isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"21395938 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"21400181 14-3-3-like protein F\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"21392415 wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"21406327 uncharacterized protein LOC21406327\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"21385349 serine\/threonine-protein kinase Nek5\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"21385923 serine\/threonine-protein kinase Nek2 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"21399051 serine\/threonine-protein kinase Nek6\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"21407331 serine\/threonine-protein kinase Nek1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"21389866 protein downstream neighbor of son homolog\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"21401299 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1 isoform X1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"21405185 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"21400570 replication stress response regulator SDE2\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"21402333 protein DECREASED SIZE EXCLUSION LIMIT 1\tK24770 DSE1; protein decreased size exclusion limit 1"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"21402822 helicase and polymerase-containing protein TEBICHI\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"21387670 LOW QUALITY PROTEIN: DNA polymerase V\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"21397924 DNA polymerase V\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"21397373 DNA-directed primase\/polymerase protein\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"21392955 LOW QUALITY PROTEIN: 5' exonuclease Apollo\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"21401593 LOW QUALITY PROTEIN: DNA cross-link repair 1A protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"21405043 5' exonuclease Apollo\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"21397553 exonuclease V, chloroplastic\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"21398027 endonuclease V\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"21398352 DNA annealing helicase and endonuclease ZRANB3\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"21389812 endonuclease 1\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"21389813 endonuclease 4 isoform X1\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"21398527 endonuclease 2\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"21393626 switch 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"21389166 pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"21407254 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"21400408 pre-mRNA-splicing factor SPF27 homolog\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"21406267 protein pleiotropic regulatory locus 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"21408514 nudix hydrolase 1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"21404046 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"21390131 ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"21393349 ribonucleoside-diphosphate reductase small chain A isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"21394060 ribonucleoside-diphosphate reductase small chain\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"112093873 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"21393177 uracil-DNA glycosylase, mitochondrial\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"21392378 uncharacterized protein LOC21392378\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"21403226 DNA-3-methyladenine glycosylase 1\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"21410634 DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"21389023 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"21386424 uncharacterized protein LOC21386424\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"21394778 uncharacterized protein LOC21394778\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"21396688 uncharacterized protein LOC21396688\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"21402163 uncharacterized protein LOC21402163\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"21404071 uncharacterized protein LOC21404071\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"21409147 uncharacterized protein LOC21409147\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"21408421 formamidopyrimidine-DNA glycosylase isoform X1\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"21389840 putative DNA glycosylase At3g47830\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"21407453 endonuclease III homolog 1, chloroplastic isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"21407472 endonuclease III homolog 1, chloroplastic\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"21398595 DNA-(apurinic or apyrimidinic site) lyase, chloroplastic isoform X1\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"21400795 DNA polymerase I B, chloroplastic\/mitochondrial\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"21400795 DNA polymerase I B, chloroplastic\/mitochondrial\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"24286604 rpoB; RNA polymerase beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"24286602 rpoC2; RNA polymerase beta' subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"24286603 rpoC1; RNA polymerase beta\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"24286659 rpoA; RNA polymerase alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"21397669 LOW QUALITY PROTEIN: uncharacterized protein LOC21397669\tK07456 mutS2; DNA mismatch repair protein MutS2"
					}
					]
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"21405102 uncharacterized protein LOC21405102\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"112090327 DNA repair protein recA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"21394592 DNA repair protein recA homolog 1, chloroplastic\tK03553 recA; recombination protein RecA"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"112090327 DNA repair protein recA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"21394592 DNA repair protein recA homolog 1, chloroplastic\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"21408962 uncharacterized protein LOC21408962\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"21400355 ATP-dependent DNA helicase homolog RECG, chloroplastic isoform X1\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"21403158 DNA gyrase subunit A, chloroplastic\/mitochondrial\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"21386704 DNA gyrase subunit B, chloroplastic\/mitochondrial\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						}
						]
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"21405498 LOW QUALITY PROTEIN: uncharacterized protein LOC21405498\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"112090327 DNA repair protein recA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"21394592 DNA repair protein recA homolog 1, chloroplastic\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"21405102 uncharacterized protein LOC21405102\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"21408514 nudix hydrolase 1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"21404046 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}