{
	"name":"mpuf04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"101673526 polyubiquitin-like\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"101680590 polyubiquitin-B isoform X3\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"101687891 UBC; polyubiquitin-C\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"101673211 UBA52; ubiquitin-60S ribosomal protein L40\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"101686900 ubiquitin-like\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"101674222 RPS27A; ubiquitin-40S ribosomal protein S27a\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"106006321 UBD; LOW QUALITY PROTEIN: ubiquitin D\tK12157 UBD; ubiquitin D"
			},
			{
				"name":"101681614 NEDD8; NEDD8\tK12158 NEDD8; ubiquitin-like protein Nedd8"
			},
			{
				"name":"101691291 FAU; ubiquitin-like protein fubi and ribosomal protein S30\tK02983 RP-S30e; small subunit ribosomal protein S30e"
			},
			{
				"name":"101685709 ISG15; ubiquitin-like protein ISG15\tK12159 ISG15; ubiquitin cross-reactive protein"
			},
			{
				"name":"101673832 SUMO2; small ubiquitin-related modifier 2\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"101680914 SUMO1; small ubiquitin-related modifier 1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"101690675 SUMO3; small ubiquitin-related modifier 3\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"101675535 GABARAP; gamma-aminobutyric acid receptor-associated protein\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"101687795 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"101689809 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"101672817 ATG12; ubiquitin-like protein ATG12\tK08336 ATG12; ubiquitin-like protein ATG12"
			},
			{
				"name":"101684816 URM1; ubiquitin-related modifier 1 isoform X2\tK12161 URM1; ubiquitin related modifier 1"
			},
			{
				"name":"101675106 UFM1; ubiquitin-fold modifier 1\tK12162 UFM1; ubiquitin-fold modifier 1"
			},
			{
				"name":"101681998 UBL3; ubiquitin-like protein 3\tK28515 UBL3; membrane-anchored ubiquitin-fold protein"
			},
			{
				"name":"101688708 ZFAND4; AN1-type zinc finger protein 4\tK12163 ZFAND4; AN1-type zinc finger protein 4"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"101680877 UBA1; ubiquitin-like modifier-activating enzyme 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"101693808 SAE1; SUMO-activating enzyme subunit 1 isoform X1\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"101689072 UBA2; SUMO-activating enzyme subunit 2 isoform X1\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"101679293 UBA3; NEDD8-activating enzyme E1 catalytic subunit isoform X1\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"101682648 NAE1; NEDD8-activating enzyme E1 regulatory subunit\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"101675791 MOCS3; adenylyltransferase and sulfurtransferase MOCS3\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"101680814 UBA5; ubiquitin-like modifier-activating enzyme 5\tK12164 UBA5; ubiquitin-like modifier-activating enzyme 5"
			},
			{
				"name":"101671149 UBA7; ubiquitin-like modifier-activating enzyme 7 isoform X1\tK10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]"
			},
			{
				"name":"101692569 UBA6; ubiquitin-like modifier-activating enzyme 6 isoform X1\tK10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]"
			},
			{
				"name":"101686879 ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X3\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"101688215 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"101675784 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
			},
			{
				"name":"101683430 UBE2C; ubiquitin-conjugating enzyme E2 C isoform X1\tK06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]"
			},
			{
				"name":"101671750 UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X2\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"101676473 UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X2\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"101690999 UBE2D2; ubiquitin-conjugating enzyme E2 D2\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"101676298 UBE2E1; ubiquitin-conjugating enzyme E2 E1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"101677097 UBE2E2; ubiquitin-conjugating enzyme E2 E2\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"101683732 UBE2E3; ubiquitin-conjugating enzyme E2 E3\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"101690012 UBE2G1; ubiquitin-conjugating enzyme E2 G1 isoform X1\tK10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]"
			},
			{
				"name":"101689646 UBE2G2; ubiquitin-conjugating enzyme E2 G2\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"101684564 UBE2H; ubiquitin-conjugating enzyme E2 H isoform X1\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"101688713 UBE2J1; ubiquitin-conjugating enzyme E2 J1\tK10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]"
			},
			{
				"name":"101693314 UBE2J2; ubiquitin-conjugating enzyme E2 J2 isoform X1\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"101687643 UBE2K; ubiquitin-conjugating enzyme E2 K\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"101674853 UBE2L3; ubiquitin-conjugating enzyme E2 L3\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"101687700 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 isoform X1\tK04553 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]"
			},
			{
				"name":"101670208 ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"101681118 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"101682402 ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"101682661 UBE2N; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"101687469 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"106004527 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"101672400 UBE2O; E2\/E3 hybrid ubiquitin-protein ligase UBE2O\tK10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]"
			},
			{
				"name":"101672625 UBE2Q1; ubiquitin-conjugating enzyme E2 Q1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"101692928 UBE2Q2; ubiquitin-conjugating enzyme E2 Q2 isoform X1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"101682521 UBE2R2; ubiquitin-conjugating enzyme E2 R2\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"101691504 CDC34; ubiquitin-conjugating enzyme E2 R1\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"101694118 UBE2S; ubiquitin-conjugating enzyme E2 S\tK10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]"
			},
			{
				"name":"101674045 UBE2T; ubiquitin-conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
			},
			{
				"name":"101682049 UBE2U; ubiquitin-conjugating enzyme E2 U isoform X1\tK10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]"
			},
			{
				"name":"101687734 UBE2W; ubiquitin-conjugating enzyme E2 W\tK10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]"
			},
			{
				"name":"101674088 UBE2Z; ubiquitin-conjugating enzyme E2 Z\tK10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]"
			},
			{
				"name":"101685695 BIRC6; baculoviral IAP repeat-containing protein 6 isoform X1\tK10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"101673840 UBE2I; SUMO-conjugating enzyme UBC9\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"101685939 UBE2F; NEDD8-conjugating enzyme UBE2F\tK10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]"
			},
			{
				"name":"101687700 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 isoform X1\tK04553 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]"
			},
			{
				"name":"101676831 ATG3; ubiquitin-like-conjugating enzyme ATG3 isoform X1\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"101677619 ubiquitin-like-conjugating enzyme ATG3\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"101672543 ATG10; ubiquitin-like-conjugating enzyme ATG10 isoform X2\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
			},
			{
				"name":"101671413 UFC1; ubiquitin-fold modifier-conjugating enzyme 1\tK12165 UFC1; ufm1-conjugating enzyme 1"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"101675730 UBE3A; ubiquitin-protein ligase E3A isoform X2\tK10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]"
			},
			{
				"name":"101684341 UBE3B; ubiquitin-protein ligase E3B isoform X1\tK10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]"
			},
			{
				"name":"101692864 UBE3C; ubiquitin-protein ligase E3C isoform X2\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"101670512 UBE3D; E3 ubiquitin-protein ligase E3D isoform X1\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"101678837 SMURF2; E3 ubiquitin-protein ligase SMURF2\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"101693549 SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X4\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"101677061 ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X3\tK05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]"
			},
			{
				"name":"101682164 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1\tK05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]"
			},
			{
				"name":"101689082 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1\tK05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]"
			},
			{
				"name":"101693543 TRIP12; E3 ubiquitin-protein ligase TRIP12 isoform X1\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"101682488 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"101686331 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1\tK13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]"
			},
			{
				"name":"101670950 HUWE1; E3 ubiquitin-protein ligase HUWE1 isoform X1\tK10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]"
			},
			{
				"name":"101692085 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1\tK22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]"
			},
			{
				"name":"101674009 UBR5; E3 ubiquitin-protein ligase UBR5 isoform X1\tK10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]"
			},
			{
				"name":"101688861 G2E3; G2\/M phase-specific E3 ubiquitin-protein ligase isoform X1\tK22371 G2H3; G2\/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]"
			},
			{
				"name":"101680890 HERC1; probable E3 ubiquitin-protein ligase HERC1 isoform X1\tK10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]"
			},
			{
				"name":"101680703 E3 ubiquitin-protein ligase HERC2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
			},
			{
				"name":"101692820 HERC3; probable E3 ubiquitin-protein ligase HERC3\tK10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]"
			},
			{
				"name":"101685888 HERC4; probable E3 ubiquitin-protein ligase HERC4 isoform X1\tK10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]"
			},
			{
				"name":"101689135 E3 ubiquitin-protein ligase HACE1\tK12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]"
			},
			{
				"name":"101682814 HECW1; E3 ubiquitin-protein ligase HECW1 isoform X1\tK12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]"
			},
			{
				"name":"101691854 HECW2; E3 ubiquitin-protein ligase HECW2\tK12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]"
			},
			{
				"name":"101685294 HECTD1; E3 ubiquitin-protein ligase HECTD1 isoform X1\tK12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]"
			},
			{
				"name":"101676780 HECTD2; probable E3 ubiquitin-protein ligase HECTD2\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"101693337 HECTD3; E3 ubiquitin-protein ligase HECTD3\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"101692709 HECTD4; probable E3 ubiquitin-protein ligase HECTD4\tK17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins",
				"children":[
				{
					"name":"101673478 NDFIP2; NEDD4 family-interacting protein 2 isoform X1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"101673733 NDFIP1; NEDD4 family-interacting protein 1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"101690374 N4BP3; NEDD4-binding protein 3\tK26473 N4BP3; NEDD4-binding protein 3"
				},
				{
					"name":"101684786 UPF0472 protein C16orf72 homolog\tK27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1"
				},
				{
					"name":"101674685 UPF0472 protein C16orf72\tK27700 HAPSTR2; HUWE1-associated protein modifying stress responses 2"
				}
				]
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"101676881 UBE4A; ubiquitin conjugation factor E4 A\tK10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]"
			},
			{
				"name":"106004331 UBE4B; ubiquitin conjugation factor E4 B\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"101680664 STUB1; E3 ubiquitin-protein ligase CHIP\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"101671684 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 isoform X1\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"101689477 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			},
			{
				"name":"101675515 RBBP6; E3 ubiquitin-protein ligase RBBP6 isoform X1\tK10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]"
			},
			{
				"name":"106003378 UBOX5; RING finger protein 37 isoform X1\tK10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"101674671 RNF20; E3 ubiquitin-protein ligase BRE1A isoform X1\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				},
				{
					"name":"101684310 RNF40; E3 ubiquitin-protein ligase BRE1B\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins",
				"children":[
				{
					"name":"101671911 CBL; E3 ubiquitin-protein ligase CBL\tK04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]"
				},
				{
					"name":"101676377 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1\tK22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]"
				},
				{
					"name":"101681580 CBLC; E3 ubiquitin-protein ligase CBL-C isoform X1\tK22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"SINA (Seven in absentia) proteins",
				"children":[
				{
					"name":"101679323 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X1\tK04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]"
				},
				{
					"name":"101685217 E3 ubiquitin-protein ligase SIAH1-like\tK04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]"
				},
				{
					"name":"101683476 SIAH2; E3 ubiquitin-protein ligase SIAH2\tK08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Ligand of Numb proteins",
				"children":[
				{
					"name":"101672050 LNX2; ligand of Numb protein X 2\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101679410 LNX1; E3 ubiquitin-protein ligase LNX isoform X1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101690386 PDZRN3; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase PDZRN3\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				},
				{
					"name":"101690401 PDZRN4; PDZ domain-containing RING finger protein 4 isoform X2\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"101682934 MARCH8; E3 ubiquitin-protein ligase MARCH8 isoform X1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"101684323 MARCH1; E3 ubiquitin-protein ligase MARCH1 isoform X1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"101679198 MARCH3; E3 ubiquitin-protein ligase MARCH3\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"101683442 MARCH2; E3 ubiquitin-protein ligase MARCH2\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"101673804 MARCH4; E3 ubiquitin-protein ligase MARCH4\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"101681036 MARCH9; E3 ubiquitin-protein ligase MARCH9\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"101681840 MARCH11; E3 ubiquitin-protein ligase MARCH11\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"101672589 MARCH5; E3 ubiquitin-protein ligase MARCH5\tK10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]"
				},
				{
					"name":"101677028 MARCH6; E3 ubiquitin-protein ligase MARCH6 isoform X2\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				},
				{
					"name":"101688611 MARCH7; E3 ubiquitin-protein ligase MARCH7 isoform X1\tK10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]"
				},
				{
					"name":"101682956 MARCH10; probable E3 ubiquitin-protein ligase MARCH10 isoform X1\tK10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins",
				"children":[
				{
					"name":"101689782 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1\tK06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]"
				},
				{
					"name":"101673585 MDM4; protein Mdm4 isoform X1\tK10127 MDM4; protein Mdm4"
				}
				]
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"101684482 NFX1; transcriptional repressor NF-X1 isoform X4\tK12236 NFX1; transcriptional repressor NF-X1"
				},
				{
					"name":"101682429 NFXL1; NF-X1-type zinc finger protein NFXL1\tK15683 NFXL1; NF-X1-type zinc finger protein NFXL1"
				}
				]
			},
			{
				"name":"Pellino proteins",
				"children":[
				{
					"name":"101676425 PELI3; E3 ubiquitin-protein ligase pellino homolog 3 isoform X1\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"101676439 PELI2; E3 ubiquitin-protein ligase pellino homolog 2\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"101678806 PELI1; E3 ubiquitin-protein ligase pellino homolog 1\tK11964 PELI; pellino [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"101671297 PEX10; peroxisome biogenesis factor 10\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"101694578 PEX12; peroxisome assembly protein 12\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"101679694 PEX2; peroxisome biogenesis factor 2\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				},
				{
					"name":"101686272 LOW QUALITY PROTEIN: peroxisome biogenesis factor 2-like\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"101689578 PARK2; E3 ubiquitin-protein ligase parkin isoform X1\tK04556 PARK2; parkin [EC:2.3.2.31]"
				},
				{
					"name":"101673078 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 isoform X1\tK11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"101675026 ARIH1; E3 ubiquitin-protein ligase ARIH1\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"101690580 ARIH2; E3 ubiquitin-protein ligase ARIH2 isoform X1\tK11969 ARIH2; ariadne-2 [EC:2.3.2.31]"
				},
				{
					"name":"101684000 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"101691834 RNF14; E3 ubiquitin-protein ligase RNF14 isoform X1\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				},
				{
					"name":"101690798 RNF19A; E3 ubiquitin-protein ligase RNF19A\tK11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]"
				},
				{
					"name":"101673027 RNF19B; E3 ubiquitin-protein ligase RNF19B isoform X1\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"101688660 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1\tK11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]"
				},
				{
					"name":"101687229 RNF34; E3 ubiquitin-protein ligase RNF34 isoform X1\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"101689765 RFFL; E3 ubiquitin-protein ligase rififylin isoform X2\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"101670165 RNF144B; E3 ubiquitin-protein ligase RNF144B isoform X1\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"101670689 RNF144A; E3 ubiquitin-protein ligase RNF144A isoform X2\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"101680531 RNF168; E3 ubiquitin-protein ligase RNF168 isoform X1\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
				},
				{
					"name":"101685055 RNF169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
				},
				{
					"name":"101680935 RNF183; RING finger protein 183\tK22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]"
				},
				{
					"name":"101685084 RNF216; E3 ubiquitin-protein ligase RNF216 isoform X1\tK11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]"
				},
				{
					"name":"101685028 RNF217; probable E3 ubiquitin-protein ligase RNF217\tK11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins",
				"children":[
				{
					"name":"101691230 TRAF2; TNF receptor-associated factor 2 isoform X2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
				},
				{
					"name":"101671644 TRAF5; TNF receptor-associated factor 5 isoform X1\tK09849 TRAF5; TNF receptor-associated factor 5"
				},
				{
					"name":"101691506 TRAF6; TNF receptor-associated factor 6\tK03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]"
				},
				{
					"name":"101693830 TRAF7; E3 ubiquitin-protein ligase TRAF7 isoform X1\tK10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"TRIM\/RBCC proteins",
				"children":[
				{
					"name":"101675980 MID2; probable E3 ubiquitin-protein ligase MID2 isoform X1\tK10647 TRIM1; midline 2 [EC:2.3.2.27]"
				},
				{
					"name":"101676317 TRIM2; tripartite motif-containing protein 2 isoform X2\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"101678266 TRIM3; tripartite motif-containing protein 3 isoform X1\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"101681071 TRIM4; E3 ubiquitin-protein ligase TRIM4\tK11998 TRIM4; tripartite motif-containing protein 4 [EC:2.3.2.27]"
				},
				{
					"name":"101675922 tripartite motif-containing protein 5-like\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"101674714 TRIM22; E3 ubiquitin-protein ligase TRIM22\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"101675015 TRIM6; tripartite motif-containing protein 6 isoform X1\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"106003314 tripartite motif-containing protein 34-like isoform X1\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"101691971 TRIM7; tripartite motif-containing protein 7\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"101674202 TRIM8; probable E3 ubiquitin-protein ligase TRIM8\tK12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]"
				},
				{
					"name":"101678358 TRIM67; tripartite motif-containing protein 67 isoform X1\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"101683806 TRIM9; E3 ubiquitin-protein ligase TRIM9 isoform X6\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"101689322 TRIM10; tripartite motif-containing protein 10 isoform X1\tK12002 TRIM10; tripartite motif-containing protein 10"
				},
				{
					"name":"101687147 TRIM11; E3 ubiquitin-protein ligase TRIM11\tK10650 TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]"
				},
				{
					"name":"101676096 TRIM13; E3 ubiquitin-protein ligase TRIM13\tK12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]"
				},
				{
					"name":"101688153 TRIM14; tripartite motif-containing protein 14 isoform X1\tK12004 TRIM14; tripartite motif-containing protein 14"
				},
				{
					"name":"101689629 tripartite motif-containing protein 15 isoform X1\tK12005 TRIM15; tripartite motif-containing protein 15"
				},
				{
					"name":"101693036 TRIM16; tripartite motif-containing protein 16\tK12006 TRIM16; tripartite motif-containing protein 16 [EC:2.3.2.27]"
				},
				{
					"name":"101687438 TRIM17; E3 ubiquitin-protein ligase TRIM17\tK12007 TRIM17; tripartite motif-containing protein 17 [EC:2.3.2.27]"
				},
				{
					"name":"101680593 MID1; E3 ubiquitin-protein ligase Midline-1 isoform X1\tK08285 TRIM18; midline 1 [EC:2.3.2.27]"
				},
				{
					"name":"101676071 TRIM21; E3 ubiquitin-protein ligase TRIM21\tK10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]"
				},
				{
					"name":"101692096 TRIM23; E3 ubiquitin-protein ligase TRIM23\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"101687559 TRIM24; transcription intermediary factor 1-alpha isoform X1\tK08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]"
				},
				{
					"name":"101678535 TRIM25; E3 ubiquitin\/ISG15 ligase TRIM25\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"101690340 E3 ubiquitin\/ISG15 ligase TRIM25-like isoform X1\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"101690278 TRIM26; tripartite motif-containing protein 26\tK12008 TRIM26; tripartite motif-containing protein 26"
				},
				{
					"name":"101687618 TRIM27; zinc finger protein RFP\tK12009 TRIM27; tripartite motif-containing protein 27 [EC:2.3.2.27]"
				},
				{
					"name":"101686379 TRIM28; transcription intermediary factor 1-beta\tK08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]"
				},
				{
					"name":"101678754 TRIM29; tripartite motif-containing protein 29 isoform X1\tK12010 TRIM29; tripartite motif-containing protein 29"
				},
				{
					"name":"101689388 TRIM32; E3 ubiquitin-protein ligase TRIM32\tK10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]"
				},
				{
					"name":"101690333 TRIM33; E3 ubiquitin-protein ligase TRIM33\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
				},
				{
					"name":"101688272 TRIM35; tripartite motif-containing protein 35\tK12012 TRIM35; tripartite motif-containing protein 35"
				},
				{
					"name":"101694137 TRIM36; E3 ubiquitin-protein ligase TRIM36\tK12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]"
				},
				{
					"name":"101684102 TRIM37; E3 ubiquitin-protein ligase TRIM37 isoform X2\tK10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]"
				},
				{
					"name":"101673680 TRIM38; E3 ubiquitin-protein ligase TRIM38 isoform X1\tK12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]"
				},
				{
					"name":"101682400 E3 ubiquitin-protein ligase TRIM39 isoform X1\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"101689049 TRIM40; tripartite motif-containing protein 40\tK12016 TRIM40; tripartite motif-containing protein 40"
				},
				{
					"name":"101690656 TRIM41; E3 ubiquitin-protein ligase TRIM41 isoform X1\tK12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]"
				},
				{
					"name":"101692199 TRIM42; tripartite motif-containing protein 42\tK12018 TRIM42; tripartite motif-containing protein 42"
				},
				{
					"name":"101689221 TRIM44; tripartite motif-containing protein 44 isoform X1\tK12020 TRIM44; tripartite motif-containing protein 44"
				},
				{
					"name":"101686345 TRIM45; tripartite motif-containing protein 45\tK12021 TRIM45; tripartite motif-containing protein 45"
				},
				{
					"name":"101675918 TRIM46; tripartite motif-containing protein 46\tK12022 TRIM46; tripartite motif-containing protein 46"
				},
				{
					"name":"101672968 TRIM47; tripartite motif-containing protein 47\tK12023 TRIM47; tripartite motif-containing protein 47"
				},
				{
					"name":"101679599 TRIM50; E3 ubiquitin-protein ligase TRIM50 isoform X1\tK12024 TRIM50_73_74; tripartite motif-containing protein 50\/73\/74"
				},
				{
					"name":"101688484 TRIM52; LOW QUALITY PROTEIN: tripartite motif-containing protein 52\tK12025 TRIM52; tripartite motif-containing protein 52"
				},
				{
					"name":"101686231 TRIM54; tripartite motif-containing protein 54\tK10653 TRIM54; tripartite motif-containing protein 54"
				},
				{
					"name":"101691395 TRIM55; tripartite motif-containing protein 55 isoform X1\tK10654 TRIM55; tripartite motif-containing protein 55"
				},
				{
					"name":"101685636 TRIM56; E3 ubiquitin-protein ligase TRIM56\tK12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]"
				},
				{
					"name":"101672164 TRIM58; E3 ubiquitin-protein ligase TRIM58\tK12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]"
				},
				{
					"name":"101691962 TRIM59; tripartite motif-containing protein 59\tK12028 TRIM59; tripartite motif-containing protein 59"
				},
				{
					"name":"101686076 tripartite motif-containing protein 60-like\tK12029 TRIM60_61; tripartite motif-containing protein 60\/61"
				},
				{
					"name":"101686358 tripartite motif-containing protein 60-like\tK12029 TRIM60_61; tripartite motif-containing protein 60\/61"
				},
				{
					"name":"101671968 TRIM62; E3 ubiquitin-protein ligase TRIM62\tK12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]"
				},
				{
					"name":"101682637 TRIM63; E3 ubiquitin-protein ligase TRIM63\tK10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]"
				},
				{
					"name":"101672965 TRIM65; tripartite motif-containing protein 65 isoform X1\tK12031 TRIM65; tripartite motif-containing protein 65"
				},
				{
					"name":"101691124 TRIM66; tripartite motif-containing protein 66 isoform X1\tK12032 TRIM66; tripartite motif-containing protein 66"
				},
				{
					"name":"101677164 TRIM68; E3 ubiquitin-protein ligase TRIM68 isoform X1\tK12033 TRIM68; tripartite motif-containing protein 68 [EC:2.3.2.27]"
				},
				{
					"name":"101674891 TRIM69; E3 ubiquitin-protein ligase TRIM69\tK12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]"
				},
				{
					"name":"101681996 TRIM71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
				},
				{
					"name":"101675299 TRIM72; tripartite motif-containing protein 72\tK12036 TRIM72; tripartite motif-containing protein 72"
				},
				{
					"name":"101686642 putative tripartite motif-containing protein 75\tK12037 TRIM75; tripartite motif-containing protein 75"
				},
				{
					"name":"101688276 putative tripartite motif-containing protein 75\tK12037 TRIM75; tripartite motif-containing protein 75"
				}
				]
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"101682186 UBR1; E3 ubiquitin-protein ligase UBR1 isoform X1\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"101683881 UBR2; E3 ubiquitin-protein ligase UBR2 isoform X1\tK10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]"
				},
				{
					"name":"101674861 UBR3; E3 ubiquitin-protein ligase UBR3\tK11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]"
				},
				{
					"name":"101685556 UBR4; E3 ubiquitin-protein ligase UBR4 isoform X4\tK10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]"
				},
				{
					"name":"101683265 UBR7; putative E3 ubiquitin-protein ligase UBR7\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"101672768 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"101685435 AIRE; autoimmune regulator\tK10603 AIRE; autoimmune regulator"
				},
				{
					"name":"101682081 BFAR; bifunctional apoptosis regulator\tK15684 BFAR; bifunctional apoptosis regulator"
				},
				{
					"name":"101691821 BIRC2; baculoviral IAP repeat-containing protein 2\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"101692293 baculoviral IAP repeat-containing protein 3\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"101671154 XIAP; E3 ubiquitin-protein ligase XIAP isoform X1\tK04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]"
				},
				{
					"name":"101687448 BIRC7; baculoviral IAP repeat-containing protein 7 isoform X1\tK16061 BIRC7_8; baculoviral IAP repeat-containing protein 7\/8"
				},
				{
					"name":"101672981 BRAP; BRCA1-associated protein isoform X1\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"101671098 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"101676237 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
				},
				{
					"name":"101671139 CCNB1IP1; E3 ubiquitin-protein ligase CCNB1IP1\tK10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]"
				},
				{
					"name":"101692918 E3 ubiquitin-protein ligase CHFR isoform X1\tK10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]"
				},
				{
					"name":"101692095 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"101677201 DCST1; DC-STAMP domain-containing protein 1 isoform X1\tK22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]"
				},
				{
					"name":"101672362 DTX2; probable E3 ubiquitin-protein ligase DTX2 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101674701 DTX4; E3 ubiquitin-protein ligase DTX4 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101683829 DTX3L; E3 ubiquitin-protein ligase DTX3L isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101690240 DTX3; probable E3 ubiquitin-protein ligase DTX3 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101693292 DTX1; E3 ubiquitin-protein ligase DTX1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101682748 DZIP3; E3 ubiquitin-protein ligase DZIP3 isoform X1\tK10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]"
				},
				{
					"name":"101686600 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
				},
				{
					"name":"101670676 KCMF1; E3 ubiquitin-protein ligase KCMF1\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"101688114 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase KCMF1-like\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"101678471 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 isoform X1\tK10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]"
				},
				{
					"name":"101682601 LTN1; E3 ubiquitin-protein ligase listerin isoform X2\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"101689561 MAP3K1; mitogen-activated protein kinase kinase kinase 1\tK04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
				},
				{
					"name":"101683372 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"101683888 MEX3B; RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"101686855 MEX3A; LOW QUALITY PROTEIN: RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"101686632 MGRN1; E3 ubiquitin-protein ligase MGRN1 isoform X1\tK10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]"
				},
				{
					"name":"101674465 MIB1; E3 ubiquitin-protein ligase MIB1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"101679379 MIB2; E3 ubiquitin-protein ligase MIB2 isoform X1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"101675654 MKRN1; E3 ubiquitin-protein ligase makorin-1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"101681923 MKRN3; probable E3 ubiquitin-protein ligase makorin-3\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"101691527 MKRN2; probable E3 ubiquitin-protein ligase makorin-2 isoform X1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"101673426 MUL1; mitochondrial ubiquitin ligase activator of NFKB 1 isoform X1\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"101692610 MYCBP2; E3 ubiquitin-protein ligase MYCBP2 isoform X8\tK10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]"
				},
				{
					"name":"101675637 MYLIP; E3 ubiquitin-protein ligase MYLIP\tK10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]"
				},
				{
					"name":"101689107 NEURL1; E3 ubiquitin-protein ligase NEURL1 isoform X1\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"101693863 NEURL1B; E3 ubiquitin-protein ligase NEURL1B\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"101673147 NEURL3; E3 ubiquitin-protein ligase NEURL3\tK15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]"
				},
				{
					"name":"101680807 NHLRC1; E3 ubiquitin-protein ligase NHLRC1\tK10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]"
				},
				{
					"name":"101671031 RNF219; RING finger protein 219\tK24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]"
				},
				{
					"name":"101677007 PJA1; E3 ubiquitin-protein ligase Praja-1 isoform X1\tK10633 PJA1; E3 ubiquitin-protein ligase Praja1 [EC:2.3.2.27]"
				},
				{
					"name":"101683877 PJA2; E3 ubiquitin-protein ligase Praja-2 isoform X1\tK10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]"
				},
				{
					"name":"101685431 RAD18; E3 ubiquitin-protein ligase RAD18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"101691963 RAG1; V(D)J recombination-activating protein 1\tK10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101671466 RCHY1; RING finger and CHY zinc finger domain-containing protein 1\tK10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101670050 RC3H1; roquin-1 isoform X1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"101678681 RC3H2; roquin-2 isoform X1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"101691897 RFWD2; E3 ubiquitin-protein ligase RFWD2 isoform X1\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
				},
				{
					"name":"101670918 RFWD3; E3 ubiquitin-protein ligase RFWD3\tK15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]"
				},
				{
					"name":"101680846 RING1; E3 ubiquitin-protein ligase RING1\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101691189 RNF2; E3 ubiquitin-protein ligase RING2\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101686437 RNF4; E3 ubiquitin-protein ligase RNF4\tK22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]"
				},
				{
					"name":"101683180 RNF5; E3 ubiquitin-protein ligase RNF5\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"101686801 RNF185; E3 ubiquitin-protein ligase RNF185\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"101677404 RNF6; E3 ubiquitin-protein ligase RNF6\tK22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]"
				},
				{
					"name":"101681331 RNF10; RING finger protein 10 isoform X1\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"101671501 RNF11; RING finger protein 11\tK11980 RNF11; E3 ubiquitin-protein ligase RNF11"
				},
				{
					"name":"101682301 RLIM; E3 ubiquitin-protein ligase RLIM\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"101688404 E3 ubiquitin-protein ligase RLIM-like\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"101678672 RNF13; E3 ubiquitin-protein ligase RNF13\tK15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]"
				},
				{
					"name":"101689650 RNF25; E3 ubiquitin-protein ligase RNF25\tK10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]"
				},
				{
					"name":"101673558 RNF26; RING finger protein 26\tK15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]"
				},
				{
					"name":"101677500 RNF44; RING finger protein 44 isoform X1\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"101692878 RNF38; E3 ubiquitin-protein ligase RNF38 isoform X2\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"101684890 RNF41; E3 ubiquitin-protein ligase NRDP1 isoform X1\tK11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]"
				},
				{
					"name":"101690062 RNF43; E3 ubiquitin-protein ligase RNF43\tK15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]"
				},
				{
					"name":"101683312 RNF103; E3 ubiquitin-protein ligase RNF103 isoform X1\tK15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]"
				},
				{
					"name":"101670623 RNF111; E3 ubiquitin-protein ligase Arkadia isoform X1\tK10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]"
				},
				{
					"name":"101677196 RNF112; RING finger protein 112 isoform X1\tK25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]"
				},
				{
					"name":"101680534 RNF114; E3 ubiquitin-protein ligase RNF114\tK15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]"
				},
				{
					"name":"101683680 RNF115; E3 ubiquitin-protein ligase RNF115 isoform X1\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"101689220 RNF126; E3 ubiquitin-protein ligase RNF126\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"101682459 RNF175; RING finger protein 175\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"101693069 RNF121; RING finger protein 121 isoform X1\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"101681829 RNF122; RING finger protein 122 isoform X1\tK15699 RNF122; RING finger protein 122"
				},
				{
					"name":"101676335 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X2\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101693885 RNF125; E3 ubiquitin-protein ligase RNF125 isoform X1\tK12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]"
				},
				{
					"name":"101694275 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF128\tK10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]"
				},
				{
					"name":"106007463 E3 ubiquitin-protein ligase RNF128-like\tK10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]"
				},
				{
					"name":"101678993 RNF130; E3 ubiquitin-protein ligase RNF130 isoform X2\tK15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]"
				},
				{
					"name":"101689459 RNF133; E3 ubiquitin-protein ligase RNF133\tK15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]"
				},
				{
					"name":"101678127 RNF135; E3 ubiquitin-protein ligase RNF135 isoform X1\tK16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]"
				},
				{
					"name":"101694549 RNF138; E3 ubiquitin-protein ligase RNF138 isoform X1\tK10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]"
				},
				{
					"name":"101681962 RNF139; E3 ubiquitin-protein ligase RNF139\tK15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]"
				},
				{
					"name":"101677025 RNF145; RING finger protein 145\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"101677896 RNF146; E3 ubiquitin-protein ligase RNF146\tK15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]"
				},
				{
					"name":"101692335 RNF149; E3 ubiquitin-protein ligase RNF149 isoform X1\tK15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]"
				},
				{
					"name":"101671597 RNF152; E3 ubiquitin-protein ligase RNF152\tK15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]"
				},
				{
					"name":"101672691 RNF157; RING finger protein 157 isoform X1\tK25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]"
				},
				{
					"name":"101672234 RNF165; RING finger protein 165\tK17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]"
				},
				{
					"name":"101670917 RNF166; RING finger protein 166 isoform X1\tK17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]"
				},
				{
					"name":"101694517 RNF167; E3 ubiquitin-protein ligase RNF167 isoform X1\tK15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]"
				},
				{
					"name":"101670159 RNF170; E3 ubiquitin-protein ligase RNF170\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"106003362 E3 ubiquitin-protein ligase RNF170-like\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"101671680 RNF180; E3 ubiquitin-protein ligase RNF180\tK15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]"
				},
				{
					"name":"101677433 RNF181; E3 ubiquitin-protein ligase RNF181\tK22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]"
				},
				{
					"name":"101693656 RNF182; E3 ubiquitin-protein ligase RNF182\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"101682726 RNF186; RING finger protein 186\tK25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]"
				},
				{
					"name":"101691055 RNF187; E3 ubiquitin-protein ligase RNF187\tK15709 RNF187; E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27]"
				},
				{
					"name":"101692786 RNF213; E3 ubiquitin-protein ligase RNF213 isoform X1\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"101676450 RNF220; E3 ubiquitin-protein ligase RNF220 isoform X1\tK25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]"
				},
				{
					"name":"101678328 RNFT1; RING finger and transmembrane domain-containing protein 1 isoform X1\tK22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]"
				},
				{
					"name":"101689401 RNFT2; RING finger and transmembrane domain-containing protein 2 isoform X1\tK28516 RNFT2; E3 ubiquitin-protein ligase RNFT2"
				},
				{
					"name":"101692495 SART1; U4\/U6.U5 tri-snRNP-associated protein 1\tK11984 SART1; U4\/U6.U5 tri-snRNP-associated protein 1"
				},
				{
					"name":"101686452 SHPRH; E3 ubiquitin-protein ligase SHPRH isoform X1\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"101676842 SH3RF3; SH3 domain-containing RING finger protein 3\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"101683084 SH3RF1; E3 ubiquitin-protein ligase SH3RF1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"101684961 SH3RF2; putative E3 ubiquitin-protein ligase SH3RF2 isoform X1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"101694606 HLTF; helicase-like transcription factor isoform X1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"101690805 SYVN1; E3 ubiquitin-protein ligase synoviolin isoform X1\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"101694188 TMEM129; E3 ubiquitin-protein ligase TM129 isoform X1\tK22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]"
				},
				{
					"name":"101689262 TOPORS; E3 ubiquitin-protein ligase Topors isoform X1\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
				},
				{
					"name":"101670658 TRAIP; E3 ubiquitin-protein ligase TRAIP isoform X1\tK11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]"
				},
				{
					"name":"101693875 TTC3; E3 ubiquitin-protein ligase TTC3\tK15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]"
				},
				{
					"name":"101693823 UHRF1; E3 ubiquitin-protein ligase UHRF1 isoform X1\tK10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]"
				},
				{
					"name":"101679192 E3 ubiquitin-protein ligase UHRF2\tK15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]"
				},
				{
					"name":"106003312 E3 ubiquitin-protein ligase UHRF2\tK15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]"
				},
				{
					"name":"101672403 UNKL; putative E3 ubiquitin-protein ligase UNKL isoform X1\tK23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]"
				},
				{
					"name":"101678845 ZNF598; zinc finger protein 598\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"101670437 ZFP91; E3 ubiquitin-protein ligase ZFP91 isoform X1\tK25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]"
				},
				{
					"name":"101678401 ZNRF2; E3 ubiquitin-protein ligase ZNRF2\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101693556 ZNRF1; E3 ubiquitin-protein ligase ZNRF1\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101687749 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 isoform X1\tK16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]"
				},
				{
					"name":"101672964 ZNRF4; zinc\/RING finger protein 4\tK15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]"
				},
				{
					"name":"101691450 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2\tK15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"101672859 JADE2; protein Jade-2 isoform X2\tK22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]"
			},
			{
				"name":"101691207 E4F1; transcription factor E4F1 isoform X1\tK22401 E4F1; transcription factor E4F1 \/ E3 ubiquitin-protein ligase [EC:2.3.2.27]"
			},
			{
				"name":"101672406 NSMCE1; non-structural maintenance of chromosomes element 1 homolog isoform X1\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			},
			{
				"name":"101673981 IRF2BPL; interferon regulatory factor 2-binding protein-like\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			},
			{
				"name":"101681669 IRF2BP1; interferon regulatory factor 2-binding protein 1\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"101689262 TOPORS; E3 ubiquitin-protein ligase Topors isoform X1\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
			},
			{
				"name":"101679310 RANBP2; E3 SUMO-protein ligase RanBP2 isoform X2\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
			},
			{
				"name":"101675225 PIAS1; E3 SUMO-protein ligase PIAS1 isoform X1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"101670608 PIAS2; E3 SUMO-protein ligase PIAS2 isoform X1\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"101684246 PIAS3; E3 SUMO-protein ligase PIAS3 isoform X1\tK16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]"
			},
			{
				"name":"101678219 PIAS4; E3 SUMO-protein ligase PIAS4\tK16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]"
			},
			{
				"name":"101690003 PML; protein PML isoform X3\tK10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]"
			},
			{
				"name":"101691568 CBX4; E3 SUMO-protein ligase CBX4\tK11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]"
			},
			{
				"name":"101686233 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"101674883 RNF212; probable E3 SUMO-protein ligase RNF212 isoform X3\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"101680686 RNF212B; RING finger protein 212B isoform X1\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"101693625 ZBED1; zinc finger BED domain-containing protein 1\tK24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]"
			},
			{
				"name":"101693180 ZNF451; zinc finger protein 451 isoform X3\tK25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]"
			},
			{
				"name":"101693567 HERC5; LOW QUALITY PROTEIN: E3 ISG15--protein ligase HERC5\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"101693848 HERC6; probable E3 ubiquitin-protein ligase HERC6 isoform X1\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"101686416 UFL1; E3 UFM1-protein ligase 1\tK22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]"
			},
			{
				"name":"101687578 DCUN1D2; DCN1-like protein 2\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"101688431 DCUN1D1; DCN1-like protein 1 isoform X1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"101671431 DCUN1D3; DCN1-like protein 3\tK17823 DCUN1D3; DCN1-like protein 3"
			},
			{
				"name":"101671875 DCUN1D5; DCN1-like protein 5\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			},
			{
				"name":"101675260 DCUN1D4; DCN1-like protein 4 isoform X1\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101684109 CUL1; cullin-1\tK03347 CUL1; cullin 1"
					},
					{
						"name":"101687227 LOW QUALITY PROTEIN: uncharacterized protein LOC101687227\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"101682868 S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"101671054 FBXW11; F-box\/WD repeat-containing protein 11 isoform X1\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"101692220 BTRC; F-box\/WD repeat-containing protein 1A isoform X7\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"101688362 FBXW2; F-box\/WD repeat-containing protein 2\tK10261 FBXW2; F-box and WD-40 domain protein 2"
					},
					{
						"name":"101689884 FBXW4; LOW QUALITY PROTEIN: F-box\/WD repeat-containing protein 4\tK10262 FBXW4; F-box and WD-40 domain protein 4"
					},
					{
						"name":"101689920 FBXW5; F-box\/WD repeat-containing protein 5\tK10263 FBXW5; F-box and WD-40 domain protein 5"
					},
					{
						"name":"101671543 FBXW7; F-box\/WD repeat-containing protein 7 isoform X1\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"101694392 FBXW8; F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					},
					{
						"name":"101685367 FBXW9; F-box\/WD repeat-containing protein 9 isoform X1\tK10265 FBXW9; F-box and WD-40 domain protein 9"
					},
					{
						"name":"101693323 CDRT1; CMT1A duplicated region transcript 1 protein isoform X1\tK10266 FBXW10; F-box and WD-40 domain protein 10"
					},
					{
						"name":"101679480 F-box\/WD repeat-containing protein 12-like\tK10267 FBXW12S; F-box and WD-40 domain protein 12\/13\/14\/15\/16\/17\/19"
					},
					{
						"name":"101680197 FBXW12; F-box\/WD repeat-containing protein 12\tK10267 FBXW12S; F-box and WD-40 domain protein 12\/13\/14\/15\/16\/17\/19"
					},
					{
						"name":"101682622 SKP2; S-phase kinase-associated protein 2\tK03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)"
					},
					{
						"name":"101674892 FBXL2; F-box\/LRR-repeat protein 2 isoform X1\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"101674960 FBXL20; F-box\/LRR-repeat protein 20 isoform X1\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"101691772 FBXL3; F-box\/LRR-repeat protein 3 isoform X1\tK10269 FBXL3; F-box and leucine-rich repeat protein 3"
					},
					{
						"name":"101689858 FBXL4; F-box\/LRR-repeat protein 4\tK10270 FBXL4; F-box and leucine-rich repeat protein 4"
					},
					{
						"name":"101684221 FBXL5; F-box\/LRR-repeat protein 5\tK10271 FBXL5; F-box and leucine-rich repeat protein 5"
					},
					{
						"name":"101692532 FBXL6; F-box\/LRR-repeat protein 6\tK10272 FBXL6; F-box and leucine-rich repeat protein 6"
					},
					{
						"name":"101672921 FBXL7; F-box\/LRR-repeat protein 7 isoform X1\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"101689757 FBXL8; F-box\/LRR-repeat protein 8\tK10274 FBXL8; F-box and leucine-rich repeat protein 8"
					},
					{
						"name":"101670487 F-box\/LRR-repeat protein 20 isoform X1\tK10275 FBXL9; F-box and leucine-rich repeat protein 9"
					},
					{
						"name":"101686934 KDM2B; lysine-specific demethylase 2B isoform X1\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"101690280 KDM2A; lysine-specific demethylase 2A isoform X1\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"101690865 FBXL12; F-box\/LRR-repeat protein 12 isoform X1\tK10278 FBXL12; F-box and leucine-rich repeat protein 12"
					},
					{
						"name":"101692561 FBXL13; F-box\/LRR-repeat protein 13 isoform X1\tK10279 FBXL13; dynein regulatory complex subunit 6"
					},
					{
						"name":"101676282 FBXL14; F-box\/LRR-repeat protein 14\tK10280 FBXL14; F-box and leucine-rich repeat protein 14"
					},
					{
						"name":"101676580 FBXL15; F-box\/LRR-repeat protein 15\tK10281 FBXL15; F-box and leucine-rich repeat protein 15"
					},
					{
						"name":"101681231 FBXL16; F-box\/LRR-repeat protein 16\tK10282 FBXL16; F-box and leucine-rich repeat protein 16"
					},
					{
						"name":"101679864 FBXL17; F-box\/LRR-repeat protein 17\tK10283 FBXL17; F-box and leucine-rich repeat protein 17"
					},
					{
						"name":"101686928 FBXL18; F-box\/LRR-repeat protein 18 isoform X1\tK10284 FBXL18; F-box and leucine-rich repeat protein 18"
					},
					{
						"name":"101680454 FBXL19; F-box\/LRR-repeat protein 19 isoform X3\tK10285 FBXL19; F-box and leucine-rich repeat protein 19"
					},
					{
						"name":"101688617 FBXL21; F-box\/LRR-repeat protein 21\tK10287 FBXL21; F-box and leucine-rich repeat protein 21"
					},
					{
						"name":"101680286 FBXL22; F-box and leucine-rich protein 22\tK10288 FBXL22; F-box and leucine-rich repeat protein 22"
					},
					{
						"name":"101689386 CCNF; cyclin-F\tK10289 CCNF; F-box protein 1 (cyclin F)"
					},
					{
						"name":"101672562 FBXO2; F-box only protein 2\tK10099 FBXO2; F-box protein 2"
					},
					{
						"name":"101680274 FBXO3; F-box only protein 3\tK10290 FBXO3; F-box protein 3"
					},
					{
						"name":"101690581 FBXO4; F-box only protein 4 isoform X1\tK10291 FBXO4; F-box protein 4"
					},
					{
						"name":"101693747 FBXO5; F-box only protein 5\tK10292 FBXO5; F-box protein 5"
					},
					{
						"name":"101674087 FBXO6; F-box only protein 6\tK10100 FBXO6; F-box protein 6"
					},
					{
						"name":"101680828 FBXO7; F-box only protein 7\tK10293 FBXO7; F-box protein 7"
					},
					{
						"name":"101673437 FBXO8; F-box only protein 8\tK10294 FBXO8; F-box protein 8"
					},
					{
						"name":"106003702 FBXO9; F-box only protein 9 isoform X1\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"101675174 FBXO10; F-box only protein 10 isoform X1\tK10296 FBXO10; F-box protein 10"
					},
					{
						"name":"101670610 FBXO11; F-box only protein 11 isoform X1\tK10297 FBXO11; F-box protein 11"
					},
					{
						"name":"101688999 FBXO15; F-box only protein 15 isoform X2\tK10298 FBXO15; F-box protein 15"
					},
					{
						"name":"101673164 FBXO16; F-box only protein 16 isoform X1\tK10299 FBXO16; F-box protein 16"
					},
					{
						"name":"101678962 FBXO17; F-box only protein 17 isoform X2\tK10101 FBXO17; F-box protein 17"
					},
					{
						"name":"101683177 FBXO18; F-box only protein 18 isoform X1\tK10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]"
					},
					{
						"name":"101685506 LMO7; LIM domain only protein 7 isoform X6\tK06084 LMO7; F-box protein 20"
					},
					{
						"name":"101691766 FBXO21; F-box only protein 21 isoform X2\tK10301 FBXO21; F-box protein 21"
					},
					{
						"name":"101693677 FBXO22; F-box only protein 22 isoform X3\tK10302 FBXO22; F-box protein 22"
					},
					{
						"name":"101673206 TSPAN17; tetraspanin-17\tK10303 FBXO23; F-box protein 23"
					},
					{
						"name":"101671956 FBXO24; F-box only protein 24 isoform X1\tK10304 FBXO24; F-box protein 24"
					},
					{
						"name":"101677713 FBXO32; F-box only protein 32\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"101694554 FBXO25; F-box only protein 25 isoform X1\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"101672421 FBXO27; F-box only protein 27\tK10102 FBXO27; F-box protein 27"
					},
					{
						"name":"101676541 FBXO28; F-box only protein 28\tK10306 FBXO28; F-box protein 28"
					},
					{
						"name":"101686173 FBXO30; F-box only protein 30\tK10307 FBXO30; F-box protein 30"
					},
					{
						"name":"101676202 FBXO31; F-box only protein 31 isoform X2\tK10308 FBXO31; F-box protein 31"
					},
					{
						"name":"101681782 FBXO33; F-box only protein 33\tK10310 FBXO33; F-box protein 33"
					},
					{
						"name":"101675042 FBXO34; F-box only protein 34 isoform X2\tK10311 FBXO34; F-box protein 34"
					},
					{
						"name":"101693088 FBXO36; F-box only protein 36\tK10312 FBXO36; F-box protein 36"
					},
					{
						"name":"101669942 FBXO38; F-box only protein 38 isoform X1\tK10313 FBXO38; F-box protein 38"
					},
					{
						"name":"101686209 FBXO39; F-box only protein 39\tK10314 FBXO39; F-box protein 39"
					},
					{
						"name":"101691375 FBXO40; F-box only protein 40\tK10315 FBXO40; F-box protein 40"
					},
					{
						"name":"101692296 FBXO41; F-box only protein 41\tK10316 FBXO41; F-box protein 41"
					},
					{
						"name":"101673619 FBXO42; F-box only protein 42\tK10317 FBXO42; F-box protein 42"
					},
					{
						"name":"101691286 FBXO43; F-box only protein 43\tK10318 FBXO43; F-box protein 43"
					},
					{
						"name":"101673227 FBXO44; F-box only protein 44 isoform X1\tK10103 FBXO44; F-box protein 44"
					},
					{
						"name":"101673244 FBXO45; F-box\/SPRY domain-containing protein 1\tK10319 FBXO45; F-box protein 45"
					},
					{
						"name":"101670577 FBXO46; F-box only protein 46\tK10320 FBXO46; F-box protein 46"
					},
					{
						"name":"101678609 FBXO47; F-box only protein 47\tK10321 FBXO47; F-box protein 47"
					},
					{
						"name":"101690132 FBXO48; F-box only protein 48\tK27313 FBXO48; F-box protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101688744 CUL2; cullin-2\tK03870 CUL2; cullin 2"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"101686218 TCEB1; transcription elongation factor B polypeptide 1\tK03872 ELOC; elongin-C"
					},
					{
						"name":"101688837 TCEB2; transcription elongation factor B polypeptide 2\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101679898 VHL; von Hippel-Lindau disease tumor suppressor isoform X1\tK03871 VHL; von Hippel-Lindau disease tumor supressor"
					},
					{
						"name":"101670262 LRR1; leucine-rich repeat protein 1 isoform X1\tK10348 LRR1; LRR-repeat protein 1"
					},
					{
						"name":"101670954 FEM1C; protein fem-1 homolog C\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"101691018 protein fem-1 homolog A isoform X1\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"106003278 protein fem-1 homolog A isoform X1\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"101674615 FEM1B; protein fem-1 homolog B\tK10349 FEM1B; protein fem-1 homolog B"
					},
					{
						"name":"101673248 APPBP2; amyloid protein-binding protein 2\tK25806 APPBP2; amyloid protein-binding protein 2"
					},
					{
						"name":"101673612 KLHDC2; kelch domain-containing protein 2\tK25807 KLHDC2; kelch domain-containing protein 2"
					},
					{
						"name":"101680509 KLHDC3; kelch domain-containing protein 3\tK25808 KLHDC3; kelch domain-containing protein 3"
					},
					{
						"name":"101684084 KLHDC10; kelch domain-containing protein 10 isoform X1\tK25809 KLHDC10; kelch domain-containing protein 10"
					},
					{
						"name":"101678074 ZER1; protein zer-1 homolog isoform X2\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"101685683 ZYG11A; protein zyg-11 homolog A\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"101685971 ZYG11B; protein zyg-11 homolog B\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"101687200 ZSWIM8; zinc finger SWIM domain-containing protein 8 isoform X2\tK25207 ZSWIM8; zinc finger SWIM domain-containing protein 8"
					},
					{
						"name":"101681630 melanoma antigen preferentially expressed in tumors isoform X1\tK28155 PRAME; melanoma antigen preferentially expressed in tumors"
					}
					]
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101674635 CUL3; cullin-3\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"101670089 kelch-like protein 1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"101684173 KLHL5; kelch-like protein 5 isoform X4\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"101694417 KLHL4; kelch-like protein 4\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"106003288 KLHL1; kelch-like protein 1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"101679870 KLHL2; kelch-like protein 2\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"101684289 KLHL3; kelch-like protein 3 isoform X3\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"101691094 KLHL6; kelch-like protein 6\tK10444 KLHL6; kelch-like protein 6"
					},
					{
						"name":"101693063 KLHL7; kelch-like protein 7 isoform X1\tK10445 KLHL7; kelch-like protein 7"
					},
					{
						"name":"101677105 KLHL8; kelch-like protein 8\tK10446 KLHL8; kelch-like protein 8"
					},
					{
						"name":"101677888 KLHL9; kelch-like protein 9\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"101691622 KLHL13; kelch-like protein 13 isoform X1\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"101675807 KLHL10; kelch-like protein 10\tK10448 KLHL10; kelch-like protein 10"
					},
					{
						"name":"101675492 KLHL11; kelch-like protein 11\tK10449 KLHL11; kelch-like protein 11"
					},
					{
						"name":"101674326 KLHL12; kelch-like protein 12\tK10450 KLHL12; kelch-like protein 12"
					},
					{
						"name":"101672194 KLHL14; kelch-like protein 14 isoform X4\tK10451 KLHL14; kelch-like protein 14"
					},
					{
						"name":"101691472 KLHL15; kelch-like protein 15 isoform X1\tK10452 KLHL15; kelch-like protein 15"
					},
					{
						"name":"101674809 GAN; gigaxonin\tK10453 KLHL16; kelch-like protein 16 (gigaxonin)"
					},
					{
						"name":"101684542 KLHL17; kelch-like protein 17\tK10454 KLHL17; kelch-like protein 17 (actinfilin)"
					},
					{
						"name":"101682806 KLHL18; kelch-like protein 18 isoform X1\tK10455 KLHL18; kelch-like protein 18"
					},
					{
						"name":"101678742 KEAP1; kelch-like ECH-associated protein 1\tK10456 KLHL19; kelch-like protein 19"
					},
					{
						"name":"101692181 KLHL20; kelch-like protein 20\tK10457 KLHL20; kelch-like protein 20"
					},
					{
						"name":"101693428 KLHL21; kelch-like protein 21\tK10458 KLHL21; kelch-like protein 21"
					},
					{
						"name":"101683822 KLHL22; kelch-like protein 22 isoform X2\tK10459 KLHL22; kelch-like protein 22"
					},
					{
						"name":"101672854 KLHL23; kelch-like protein 23 isoform X1\tK10460 KLHL23; kelch-like protein 23"
					},
					{
						"name":"101684578 KLHL35; kelch-like protein 35 isoform X1\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"101691551 KLHL24; kelch-like protein 24\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"101671590 ENC1; ectoderm-neural cortex protein 1\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"101687318 KLHL25; kelch-like protein 25\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"101671445 KLHL26; kelch-like protein 26 isoform X2\tK10463 KLHL26; kelch-like protein 26"
					},
					{
						"name":"101686782 IPP; actin-binding protein IPP isoform X1\tK13956 IPP; actin-binding protein IPP"
					},
					{
						"name":"106003311 kelch-like protein 28\tK10464 KLHL28; kelch-like protein 28"
					},
					{
						"name":"101686524 KLHL29; kelch-like protein 29 isoform X1\tK10465 KLHL29; kelch-like protein 29"
					},
					{
						"name":"101688234 KLHL30; kelch-like protein 30\tK10466 KLHL30; kelch-like protein 30"
					},
					{
						"name":"101689882 KLHL31; kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"101688995 KLHL32; kelch-like protein 32 isoform X1\tK10468 KLHL32; kelch-like protein 32"
					},
					{
						"name":"101693958 KLHL33; kelch-like protein 33 isoform X2\tK13957 KLHL33; kelch-like protein 33"
					},
					{
						"name":"101674195 KLHL34; kelch-like protein 34\tK10469 KLHL34; kelch-like protein 34"
					},
					{
						"name":"101685788 KLHL36; kelch-like protein 36 isoform X1\tK13958 KLHL36; kelch-like protein 36"
					},
					{
						"name":"101678419 KLHL38; kelch-like protein 38 isoform X1\tK13959 KLHL38; kelch-like protein 38"
					},
					{
						"name":"101680170 KLHL42; kelch-like protein 42\tK27973 KLHL42; kelch-like protein 42"
					},
					{
						"name":"101693050 KBTBD2; kelch repeat and BTB domain-containing protein 2\tK10470 KBTBD2; kelch repeat and BTB domain-containing protein 2"
					},
					{
						"name":"101681753 KBTBD3; kelch repeat and BTB domain-containing protein 3\tK10471 KBTBD3; kelch repeat and BTB domain-containing protein 3"
					},
					{
						"name":"101685027 KBTBD4; kelch repeat and BTB domain-containing protein 4 isoform X1\tK10472 KBTBD4; kelch repeat and BTB domain-containing protein 4"
					},
					{
						"name":"101675608 KLHL40; kelch-like protein 40 isoform X1\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"101694357 KLHL41; kelch-like protein 41\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"101670251 KBTBD7; kelch repeat and BTB domain-containing protein 7\tK10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6\/7"
					},
					{
						"name":"101689323 KBTBD6; kelch repeat and BTB domain-containing protein 6\tK10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6\/7"
					},
					{
						"name":"101677027 KBTBD8; kelch repeat and BTB domain-containing protein 8\tK10475 KBTBD8; kelch repeat and BTB domain-containing protein 8"
					},
					{
						"name":"101675780 KBTBD11; kelch repeat and BTB domain-containing protein 11\tK10476 KBTBD11; kelch repeat and BTB domain-containing protein 11"
					},
					{
						"name":"101690121 KBTBD12; kelch repeat and BTB domain-containing protein 12 isoform X1\tK21912 KBTBD12; kelch repeat and BTB domain-containing protein 12"
					},
					{
						"name":"101691883 KBTBD13; kelch repeat and BTB domain-containing protein 13\tK21913 KBTBD13; kelch repeat and BTB domain-containing protein 13"
					},
					{
						"name":"101672477 BTBD1; BTB\/POZ domain-containing protein 1\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"101687032 BTBD2; BTB\/POZ domain-containing protein 2 isoform X1\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"101682009 BTBD3; BTB\/POZ domain-containing protein 3 isoform X1\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"106004626 BTBD6; BTB\/POZ domain-containing protein 6\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"101682585 BTBD7; BTB\/POZ domain-containing protein 7\tK10479 BTBD7; BTB\/POZ domain-containing protein 7"
					},
					{
						"name":"101686840 uncharacterized protein KIAA1107 homolog\tK10480 BTBD8; BTB\/POZ domain-containing protein 8"
					},
					{
						"name":"101683705 BTBD9; BTB\/POZ domain-containing protein 9\tK10481 BTBD9; BTB\/POZ domain-containing protein 9"
					},
					{
						"name":"101688458 BTBD10; BTB\/POZ domain-containing protein 10 isoform X1\tK10482 BTBD10; BTB\/POZ domain-containing protein 10"
					},
					{
						"name":"101675151 ankyrin repeat and BTB\/POZ domain-containing protein BTBD11 isoform X1\tK10483 BTBD11; BTB\/POZ domain-containing protein 11"
					},
					{
						"name":"101682865 SLX4; structure-specific endonuclease subunit SLX4\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"101672485 GMCL1; germ cell-less protein-like 1\tK10485 BTBD13; BTB\/POZ domain-containing protein 13 (germ cell-less protein-like 1)"
					},
					{
						"name":"101670308 NACC1; nucleus accumbens-associated protein 1 isoform X1\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"101681925 NACC2; nucleus accumbens-associated protein 2 isoform X1\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"101680456 BTBD16; BTB\/POZ domain-containing protein 16\tK10487 BTBD16; BTB\/POZ domain-containing protein 16"
					},
					{
						"name":"101677605 ZBTB1; zinc finger and BTB domain-containing protein 1 isoform X1\tK10488 ZBTB1; zinc finger and BTB domain-containing protein 1"
					},
					{
						"name":"101689213 ZBTB2; zinc finger and BTB domain-containing protein 2\tK10489 ZBTB2; zinc finger and BTB domain-containing protein 2"
					},
					{
						"name":"101685858 ZBTB3; zinc finger and BTB domain-containing protein 3\tK10490 ZBTB3; zinc finger and BTB domain-containing protein 3"
					},
					{
						"name":"101686389 ZBTB4; zinc finger and BTB domain-containing protein 4\tK10491 ZBTB4; zinc finger and BTB domain-containing protein 4"
					},
					{
						"name":"101673452 ZBTB5; zinc finger and BTB domain-containing protein 5\tK10492 ZBTB5; zinc finger and BTB domain-containing protein 5"
					},
					{
						"name":"101678380 ZBTB6; zinc finger and BTB domain-containing protein 6\tK10493 ZBTB6; zinc finger and BTB domain-containing protein 6"
					},
					{
						"name":"101679771 ZBTB7B; zinc finger and BTB domain-containing protein 7B\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"101683146 ZBTB7A; zinc finger and BTB domain-containing protein 7A\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"101690831 ZBTB7C; zinc finger and BTB domain-containing protein 7C isoform X2\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"101679109 ZBTB8A; zinc finger and BTB domain-containing protein 8A\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"101679807 ZBTB8B; zinc finger and BTB domain-containing protein 8B\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"101688628 ZBTB9; zinc finger and BTB domain-containing protein 9\tK10496 ZBTB9; zinc finger and BTB domain-containing protein 9"
					},
					{
						"name":"101689204 ZBTB10; zinc finger and BTB domain-containing protein 10 isoform X1\tK10497 ZBTB10; zinc finger and BTB domain-containing protein 10"
					},
					{
						"name":"101672787 ZBTB11; zinc finger and BTB domain-containing protein 11\tK10498 ZBTB11; zinc finger and BTB domain-containing protein 11"
					},
					{
						"name":"101691975 ZBTB12; zinc finger and BTB domain-containing protein 12\tK10499 ZBTB12; zinc finger and BTB domain-containing protein 12"
					},
					{
						"name":"101681228 ZBTB16; zinc finger and BTB domain-containing protein 16\tK10055 ZBTB16; zinc finger and BTB domain-containing protein 16"
					},
					{
						"name":"101684746 ZBTB17; zinc finger and BTB domain-containing protein 17\tK10500 ZBTB17; zinc finger and BTB domain-containing protein 17"
					},
					{
						"name":"101687165 ZBTB20; zinc finger and BTB domain-containing protein 20\tK10501 ZBTB20; zinc finger and BTB domain-containing protein 20"
					},
					{
						"name":"101683337 ZBTB22; zinc finger and BTB domain-containing protein 22\tK10502 ZBTB22; zinc finger and BTB domain-containing protein 22"
					},
					{
						"name":"101690351 ZBTB24; zinc finger and BTB domain-containing protein 24 isoform X2\tK10503 ZBTB24; zinc finger and BTB domain-containing protein 24"
					},
					{
						"name":"101678286 ZBTB25; zinc finger and BTB domain-containing protein 25\tK10504 ZBTB25; zinc finger and BTB domain-containing protein 25"
					},
					{
						"name":"101677678 ZBTB26; zinc finger and BTB domain-containing protein 26\tK10505 ZBTB26; zinc finger and BTB domain-containing protein 26"
					},
					{
						"name":"101690604 ZBTB32; zinc finger and BTB domain-containing protein 32 isoform X1\tK10506 ZBTB32; zinc finger and BTB domain-containing protein 32"
					},
					{
						"name":"101682512 ZBTB33; transcriptional regulator Kaiso\tK10507 ZBTB33; zinc finger and BTB domain-containing protein 33"
					},
					{
						"name":"101684248 ZBTB34; zinc finger and BTB domain-containing protein 34\tK10508 ZBTB34; zinc finger and BTB domain-containing protein 34"
					},
					{
						"name":"101693871 ZBTB37; zinc finger and BTB domain-containing protein 37\tK10509 ZBTB37; zinc finger and BTB domain-containing protein 37"
					},
					{
						"name":"101676894 ZBTB38; zinc finger and BTB domain-containing protein 38\tK10510 ZBTB38; zinc finger and BTB domain-containing protein 38"
					},
					{
						"name":"101674991 ZBTB39; zinc finger and BTB domain-containing protein 39\tK10511 ZBTB39; zinc finger and BTB domain-containing protein 39"
					},
					{
						"name":"101685833 ZBTB40; zinc finger and BTB domain-containing protein 40 isoform X1\tK10512 ZBTB40; zinc finger and BTB domain-containing protein 40"
					},
					{
						"name":"101674913 ZBTB41; zinc finger and BTB domain-containing protein 41 isoform X1\tK10513 ZBTB41; zinc finger and BTB domain-containing protein 41"
					},
					{
						"name":"101684537 ZBTB43; zinc finger and BTB domain-containing protein 43\tK10514 ZBTB43; zinc finger and BTB domain-containing protein 43"
					},
					{
						"name":"101685555 ZBTB44; zinc finger and BTB domain-containing protein 44 isoform X1\tK10515 ZBTB44; zinc finger and BTB domain-containing protein 44"
					},
					{
						"name":"101686865 ZBTB45; zinc finger and BTB domain-containing protein 45\tK10516 ZBTB45; zinc finger and BTB domain-containing protein 45"
					},
					{
						"name":"101672548 ZBTB46; zinc finger and BTB domain-containing protein 46 isoform X1\tK10517 ZBTB46; zinc finger and BTB domain-containing protein 46"
					},
					{
						"name":"101673385 ZBTB47; zinc finger and BTB domain-containing protein 47\tK10518 ZBTB47; zinc finger and BTB domain-containing protein 47"
					},
					{
						"name":"101691648 ZBTB48; zinc finger and BTB domain-containing protein 48 isoform X2\tK10519 ZBTB48; zinc finger and BTB domain-containing protein 48"
					},
					{
						"name":"101690967 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1 isoform X1\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					},
					{
						"name":"101681720 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2\tK10521 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2"
					},
					{
						"name":"101670559 RHOBTB2; rho-related BTB domain-containing protein 2 isoform X2\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"101674644 RHOBTB1; rho-related BTB domain-containing protein 1 isoform X1\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"101675878 RHOBTB3; rho-related BTB domain-containing protein 3\tK07869 RHOBTB3; Rho-related BTB domain-containing protein 3"
					},
					{
						"name":"101672405 KCTD13; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"101683678 KCTD10; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X2\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"101691290 TNFAIP1; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"101685654 KCTD1; BTB\/POZ domain-containing protein KCTD1\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"101692295 KCTD15; BTB\/POZ domain-containing protein KCTD15\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"101674114 KCTD2; BTB\/POZ domain-containing protein KCTD2\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"101674367 KCTD17; BTB\/POZ domain-containing protein KCTD17 isoform X1\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"101685174 KCTD5; BTB\/POZ domain-containing protein KCTD5\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"101682573 KCTD3; BTB\/POZ domain-containing protein KCTD3 isoform X1\tK21915 KCTD3; BTB\/POZ domain-containing protein KCTD3"
					},
					{
						"name":"101685633 KCTD6; BTB\/POZ domain-containing protein KCTD6 isoform X2\tK21916 KCTD6; BTB\/POZ domain-containing protein KCTD6"
					},
					{
						"name":"101676839 KCTD14; BTB\/POZ domain-containing protein KCTD14 isoform X1\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"101694337 KCTD7; BTB\/POZ domain-containing protein KCTD7 isoform X1\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"101687753 KCTD16; BTB\/POZ domain-containing protein KCTD16\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101689261 KCTD8; BTB\/POZ domain-containing protein KCTD8\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101689909 KCTD12; BTB\/POZ domain-containing protein KCTD12\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101687735 KCTD9; BTB\/POZ domain-containing protein KCTD9 isoform X1\tK21919 KCTD9; BTB\/POZ domain-containing protein KCTD9"
					},
					{
						"name":"101690430 KCTD18; BTB\/POZ domain-containing protein KCTD18\tK21921 KCTD18; BTB\/POZ domain-containing protein KCTD18"
					},
					{
						"name":"101679019 KCTD21; BTB\/POZ domain-containing protein KCTD21\tK21922 KCTD21; BTB\/POZ domain-containing protein KCTD21"
					},
					{
						"name":"101679356 DIABLO; diablo homolog, mitochondrial isoform X1\tK10522 DIABLO; diablo"
					},
					{
						"name":"101681201 SPOP; speckle-type POZ protein isoform X1\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"101685797 SPOPL; speckle-type POZ protein-like isoform X2\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"101680523 LZTR1; leucine-zipper-like transcriptional regulator 1\tK23330 LZTR1; leucine-zipper-like transcriptional regulator 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101678599 CUL4B; cullin-4B isoform X1\tK10609 CUL4; cullin 4"
					},
					{
						"name":"101688438 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"101685765 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
					},
					{
						"name":"101688882 DNA damage-binding protein 1-like\tK10610 DDB1; DNA damage-binding protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"101691261 DDB2; DNA damage-binding protein 2\tK10140 DDB2; DNA damage-binding protein 2"
					},
					{
						"name":"101680527 ERCC8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
					},
					{
						"name":"101692856 DET1; DET1 homolog\tK10571 DET1; de-etiolated-1"
					},
					{
						"name":"101691897 RFWD2; E3 ubiquitin-protein ligase RFWD2 isoform X1\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
					},
					{
						"name":"101673975 DDA1; DET1- and DDB1-associated protein 1\tK11792 DDA1; DET1- and DDB1-associated protein 1"
					},
					{
						"name":"101675039 CRBN; protein cereblon isoform X1\tK11793 CRBN; cereblon"
					},
					{
						"name":"101671084 torsin-1A-interacting protein 2, isoform IFRG15\tK11794 IFRG15; IFRG15 protein"
					},
					{
						"name":"101671791 TRPC4AP; short transient receptor potential channel 4-associated protein\tK11796 TRPC4AP; Trpc4-associated protein"
					},
					{
						"name":"101689227 VPRBP; protein VPRBP isoform X1\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
					},
					{
						"name":"101674916 DTL; denticleless protein homolog isoform X1\tK11790 DTL; denticleless"
					},
					{
						"name":"101690085 DCAF4; DDB1- and CUL4-associated factor 4\tK11799 DCAF4; DDB1- and CUL4-associated factor 4"
					},
					{
						"name":"101675847 DCAF5; DDB1- and CUL4-associated factor 5\tK11800 DCAF5; DDB1- and CUL4-associated factor 5"
					},
					{
						"name":"101678377 DCAF6; DDB1- and CUL4-associated factor 6\tK11795 DCAF6; DDB1- and CUL4-associated factor 6"
					},
					{
						"name":"101676179 DCAF7; DDB1- and CUL4-associated factor 7\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"101680355 DCAF8; DDB1- and CUL4-associated factor 8\tK11804 DCAF8; DDB1- and CUL4-associated factor 8"
					},
					{
						"name":"101670671 WDTC1; WD and tetratricopeptide repeats protein 1 isoform X1\tK11807 WDTC1; WD and tetratricopeptide repeats protein 1"
					},
					{
						"name":"101678826 DCAF10; LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 10\tK11802 DCAF10; DDB1- and CUL4-associated factor 10"
					},
					{
						"name":"101691960 DCAF11; DDB1- and CUL4-associated factor 11 isoform X3\tK11801 DCAF11; DDB1- and CUL4-associated factor 11"
					},
					{
						"name":"101670446 LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"101673921 DCAF12; DDB1- and CUL4-associated factor 12 isoform X1\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"101688677 LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"101673736 DCAF13; DDB1- and CUL4-associated factor 13\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"101687504 PHIP; PH-interacting protein isoform X1\tK11797 PHIP; PH-interacting protein"
					},
					{
						"name":"101686254 DCAF15; DDB1- and CUL4-associated factor 15\tK11791 DCAF15; DDB1- and CUL4-associated factor 15"
					},
					{
						"name":"101690538 DCAF16; DDB1- and CUL4-associated factor 16\tK23626 DCAF16; DDB1- and CUL4-associated factor 16"
					},
					{
						"name":"101677913 DCAF17; DDB1- and CUL4-associated factor 17 isoform X1\tK23331 DCAF17; DDB1- and CUL4-associated factor 17"
					},
					{
						"name":"101675333 BRWD3; bromodomain and WD repeat-containing protein 3 isoform X2\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"101694427 BRWD1; bromodomain and WD repeat-containing protein 1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"101679393 WDR26; WD repeat-containing protein 26 isoform X4\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"101694058 WDR70; WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"101670423 WDR76; WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101675609 RNF7; RING-box protein 2 isoform X1\tK10611 RBX2; RING-box protein 2"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101675553 CUL5; cullin-5\tK10612 CUL5; cullin 5"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"101686218 TCEB1; transcription elongation factor B polypeptide 1\tK03872 ELOC; elongin-C"
					},
					{
						"name":"101688837 TCEB2; transcription elongation factor B polypeptide 2\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101678788 CISH; cytokine-inducible SH2-containing protein\tK04701 CISH; cytokine inducible SH2-containing protein"
					},
					{
						"name":"101691205 SOCS1; suppressor of cytokine signaling 1\tK04694 SOCS1; suppressor of cytokine signaling 1"
					},
					{
						"name":"101680544 SOCS2; suppressor of cytokine signaling 2 isoform X1\tK04695 SOCS2; suppressor of cytokine signaling 2"
					},
					{
						"name":"101675383 SOCS3; suppressor of cytokine signaling 3\tK04696 SOCS3; suppressor of cytokine signaling 3"
					},
					{
						"name":"101673021 SOCS4; suppressor of cytokine signaling 4\tK04697 SOCS4; suppressor of cytokine signaling 4"
					},
					{
						"name":"101681703 SOCS5; suppressor of cytokine signaling 5\tK04698 SOCS5; suppressor of cytokine signaling 5"
					},
					{
						"name":"101683213 SOCS7; suppressor of cytokine signaling 7\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"101686333 SOCS6; suppressor of cytokine signaling 6 isoform X1\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"101690893 ASB1; ankyrin repeat and SOCS box protein 1\tK10323 ASB1; ankyrin repeat and SOCS box protein 1"
					},
					{
						"name":"101679169 ASB2; ankyrin repeat and SOCS box protein 2\tK10324 ASB2; ankyrin repeat and SOCS box protein 2"
					},
					{
						"name":"101679554 ASB3; ankyrin repeat and SOCS box protein 3 isoform X1\tK10325 ASB3; ankyrin repeat and SOCS box protein 3"
					},
					{
						"name":"101686144 ASB4; ankyrin repeat and SOCS box protein 4\tK10326 ASB4; ankyrin repeat and SOCS box protein 4"
					},
					{
						"name":"101693191 ASB5; ankyrin repeat and SOCS box protein 5 isoform X1\tK10327 ASB5; ankyrin repeat and SOCS box protein 5"
					},
					{
						"name":"101694038 ASB6; ankyrin repeat and SOCS box protein 6 isoform X1\tK10328 ASB6; ankyrin repeat and SOCS box protein 6"
					},
					{
						"name":"101689727 ASB7; ankyrin repeat and SOCS box protein 7\tK10329 ASB7; ankyrin repeat and SOCS box protein 7"
					},
					{
						"name":"101687649 ASB8; ankyrin repeat and SOCS box protein 8\tK10330 ASB8; ankyrin repeat and SOCS box protein 8"
					},
					{
						"name":"101670841 ASB9; ankyrin repeat and SOCS box protein 9\tK10331 ASB9; ankyrin repeat and SOCS box protein 9"
					},
					{
						"name":"101682524 ASB10; ankyrin repeat and SOCS box protein 10 isoform X1\tK10332 ASB10; ankyrin repeat and SOCS box protein 10"
					},
					{
						"name":"101671140 ASB11; ankyrin repeat and SOCS box protein 11 isoform X1\tK10333 ASB11; ankyrin repeat and SOCS box protein 11"
					},
					{
						"name":"101676524 ASB12; ankyrin repeat and SOCS box protein 12 isoform X1\tK10334 ASB12; ankyrin repeat and SOCS box protein 12"
					},
					{
						"name":"101675222 ASB13; ankyrin repeat and SOCS box protein 13\tK10335 ASB13; ankyrin repeat and SOCS box protein 13"
					},
					{
						"name":"101677603 ASB14; ankyrin repeat and SOCS box protein 14 isoform X1\tK10336 ASB14; ankyrin repeat and SOCS box protein 14"
					},
					{
						"name":"101686030 ASB15; ankyrin repeat and SOCS box protein 15 isoform X1\tK10337 ASB15; ankyrin repeat and SOCS box protein 15"
					},
					{
						"name":"101684111 ASB16; ankyrin repeat and SOCS box protein 16\tK10338 ASB16; ankyrin repeat and SOCS box protein 16"
					},
					{
						"name":"101676614 ASB17; ankyrin repeat and SOCS box protein 17 isoform X1\tK10339 ASB17; ankyrin repeat and SOCS box protein 17"
					},
					{
						"name":"101681712 ASB18; ankyrin repeat and SOCS box protein 18\tK10340 ASB18; ankyrin repeat and SOCS box protein 18"
					},
					{
						"name":"101672780 WSB1; WD repeat and SOCS box-containing protein 1 isoform X1\tK10341 WSB1; WD repeat and SOCS box-containing protein 1"
					},
					{
						"name":"101693194 WSB2; WD repeat and SOCS box-containing protein 2\tK10342 WSB2; WD repeat and SOCS box-containing protein 2"
					},
					{
						"name":"101676523 SPSB4; SPRY domain-containing SOCS box protein 4\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"101678122 SPSB1; SPRY domain-containing SOCS box protein 1\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"101680735 SPSB2; SPRY domain-containing SOCS box protein 2\tK10344 SPSB2; SPRY domain-containing SOCS box protein 2"
					},
					{
						"name":"101685487 SPSB3; SPRY domain-containing SOCS box protein 3\tK10345 SPSB3; SPRY domain-containing SOCS box protein 3"
					},
					{
						"name":"101685369 RAB40B; ras-related protein Rab-40B isoform X1\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"101691026 RAB40C; ras-related protein Rab-40C isoform X1\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"101680911 LRRC41; leucine-rich repeat-containing protein 41 isoform X1\tK10347 LRRC41; leucine-rich repeat-containing protein 41"
					},
					{
						"name":"101685750 RSPRY1; RING finger and SPRY domain-containing protein 1\tK23332 RSPRY1; RING finger and SPRY domain-containing protein 1"
					},
					{
						"name":"101676510 ANKRD9; ankyrin repeat domain-containing protein 9\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"101673020 KLHDC1; kelch domain-containing protein 1 isoform X2\tK25810 KLHDC1; kelch domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101675640 CUL7; cullin-7 isoform X1\tK10613 CUL7; cullin 7"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"101682868 S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101694392 FBXW8; F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101687674 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101674166 CUL9; cullin-9 isoform X1\tK11970 CUL9; cullin 9"
					}
					]
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101674396 ANAPC11; anaphase-promoting complex subunit 11\tK03358 APC11; anaphase-promoting complex subunit 11"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101686101 ANAPC2; anaphase-promoting complex subunit 2\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101672474 CDC20; cell division cycle protein 20 homolog\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"101694007 FZR1; fizzy-related protein homolog isoform X1\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"101687672 ANAPC1; anaphase-promoting complex subunit 1 isoform X1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"101676686 CDC27; cell division cycle protein 27 homolog isoform X1\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"101684946 ANAPC4; anaphase-promoting complex subunit 4 isoform X1\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"101687600 ANAPC5; anaphase-promoting complex subunit 5 isoform X2\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"101686422 CDC16; cell division cycle protein 16 homolog\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"101690928 ANAPC7; anaphase-promoting complex subunit 7 isoform X1\tK03354 APC7; anaphase-promoting complex subunit 7"
					},
					{
						"name":"101680528 CDC23; cell division cycle protein 23 homolog\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"101677680 ANAPC10; anaphase-promoting complex subunit 10\tK03357 APC10; anaphase-promoting complex subunit 10"
					},
					{
						"name":"101680241 CDC26; anaphase-promoting complex subunit CDC26 isoform X1\tK03359 APC12; anaphase-promoting complex subunit 12"
					},
					{
						"name":"101672178 ANAPC13; anaphase-promoting complex subunit 13\tK12456 APC13; anaphase-promoting complex subunit 13"
					},
					{
						"name":"101692406 ANAPC15; anaphase-promoting complex subunit 15 isoform X1\tK25228 APC15; anaphase-promoting complex subunit 15"
					},
					{
						"name":"101682251 ANAPC16; anaphase-promoting complex subunit 16\tK25229 APC16; anaphase-promoting complex subunit 16"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"101671098 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"101687876 BRCA2; breast cancer type 2 susceptibility protein isoform X3\tK08775 BRCA2; breast cancer 2 susceptibility protein"
				},
				{
					"name":"101684244 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"101670782 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
				},
				{
					"name":"101680577 BRE; BRCA1-A complex subunit BRE\tK12173 BRE; BRCA1-A complex subunit BRE"
				},
				{
					"name":"101672111 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex",
				"children":[
				{
					"name":"101676335 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X2\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101684249 UBAC1; ubiquitin-associated domain-containing protein 1\tK12174 KPC2; Kip1 ubiquitination-promoting complex protein 2"
				}
				]
			},
			{
				"name":"LUBAC complex",
				"children":[
				{
					"name":"101673087 sharpin\tK20894 SHARPIN; shank-associated RH domain-interacting protein"
				},
				{
					"name":"101684000 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"101688660 RNF31; E3 ubiquitin-protein ligase RNF31 isoform X1\tK11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"101684853 RMND5A; protein RMD5 homolog A\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"101688963 RMND5B; protein RMD5 homolog B\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"101677377 RANBP9; ran-binding protein 9\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"101687084 RANBP10; ran-binding protein 10 isoform X1\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"101686397 ARMC8; armadillo repeat-containing protein 8 isoform X1\tK23336 ARMC8; armadillo repeat-containing protein 8"
				},
				{
					"name":"101677336 MKLN1; muskelin isoform X1\tK23337 MKLN1; muskelin"
				},
				{
					"name":"101672873 MAEA; macrophage erythroblast attacher isoform X1\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"101681247 GID4; glucose-induced degradation protein 4 homolog\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"101686485 GID8; glucose-induced degradation protein 8 homolog\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"101673572 YPEL5; protein yippee-like 5\tK23339 YPEL5; protein yippee-like 5"
				},
				{
					"name":"101679393 WDR26; WD repeat-containing protein 26 isoform X4\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex",
				"children":[
				{
					"name":"101672768 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"101680630 TMUB1; transmembrane and ubiquitin-like domain-containing protein 1 isoform X1\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"101681408 TMUB2; transmembrane and ubiquitin-like domain-containing protein 2 isoform X2\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"101675334 ERLIN2; erlin-2\tK23341 ERLIN; erlin"
				},
				{
					"name":"101681692 ERLIN1; erlin-1\tK23341 ERLIN; erlin"
				}
				]
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex",
				"children":[
				{
					"name":"101693944 LMBR1L; protein LMBR1L isoform X1\tK25215 LMBR1L; protein LMBR1L"
				},
				{
					"name":"101672768 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"101670090 UBAC2; ubiquitin-associated domain-containing protein 2\tK25216 UBAC2; ubiquitin-associated domain-containing protein 2"
				}
				]
			},
			{
				"name":"STUB1-CHIC2  complex",
				"children":[
				{
					"name":"101680664 STUB1; E3 ubiquitin-protein ligase CHIP\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101681006 CHIC2; cysteine-rich hydrophobic domain-containing protein 2\tK28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2"
				}
				]
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"101670005 CAND1; cullin-associated NEDD8-dissociated protein 1\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				},
				{
					"name":"101692277 CAND2; cullin-associated NEDD8-dissociated protein 2\tK24172 CAND2; cullin-associated NEDD8-dissociated protein 2"
				},
				{
					"name":"101670987 COMMD1; COMM domain-containing protein 1\tK22557 COMMD1; COMM domain containing 1"
				},
				{
					"name":"101677473 COMMD2; COMM domain-containing protein 2 isoform X1\tK22558 COMMD2; COMM domain containing 2"
				},
				{
					"name":"106003368 COMMD3; COMM domain-containing protein 3\tK22559 COMMD3; COMM domain containing 3"
				},
				{
					"name":"101682997 COMMD4; COMM domain-containing protein 4 isoform X2\tK22560 COMMD4; COMM domain containing 4"
				},
				{
					"name":"101684706 COMMD5; COMM domain-containing protein 5\tK22561 COMMD5; COMM domain containing 5"
				},
				{
					"name":"101685192 COMMD6; COMM domain-containing protein 6\tK22562 COMMD6; COMM domain containing 6"
				},
				{
					"name":"101683433 COMMD7; COMM domain-containing protein 7\tK22563 COMMD7; COMM domain containing 7"
				},
				{
					"name":"101694256 COMMD8; COMM domain-containing protein 8\tK22564 COMMD8; COMM domain containing 8"
				},
				{
					"name":"101675013 COMMD9; COMM domain-containing protein 9\tK22565 COMMD9; COMM domain containing 9"
				},
				{
					"name":"101675229 COMMD10; COMM domain-containing protein 10\tK22566 COMMD10; COMM domain containing 10"
				},
				{
					"name":"101689797 CCDC22; coiled-coil domain-containing protein 22\tK23343 CCDC22; coiled-coil domain-containing protein 22"
				},
				{
					"name":"101692886 DDRGK1; DDRGK domain-containing protein 1\tK23344 DDRGK1; DDRGK domain-containing protein 1"
				},
				{
					"name":"101685389 GLMN; glomulin\tK23345 GLMN; glomulin"
				},
				{
					"name":"101692675 IVNS1ABP; influenza virus NS1A-binding protein\tK15046 IVNS1ABP; influenza virus NS1A-binding protein"
				},
				{
					"name":"101681672 UBXN7; UBX domain-containing protein 7 isoform X1\tK24350 UBXN7; UBX domain-containing protein 7"
				},
				{
					"name":"101678032 PACRG; parkin coregulated gene protein isoform X1\tK26163 PACRG; parkin coregulated gene protein"
				},
				{
					"name":"101679672 UBAP2L; ubiquitin-associated protein 2-like isoform X12\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"101681103 UBAP2; ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"101689296 UEVLD; ubiquitin-conjugating enzyme E2 variant 3 isoform X1\tK28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"101671160 UCHL1; ubiquitin carboxyl-terminal hydrolase isozyme L1\tK05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]"
				},
				{
					"name":"101678284 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1\tK08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]"
				},
				{
					"name":"101688658 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"101687217 UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"101688614 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD isoform X2\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"101689117 USP1; ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"101675493 USP2; ubiquitin carboxyl-terminal hydrolase 2 isoform X1\tK11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]"
				},
				{
					"name":"101681537 USP3; ubiquitin carboxyl-terminal hydrolase 3 isoform X3\tK11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]"
				},
				{
					"name":"101678667 USP11; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 11\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"101680498 USP4; ubiquitin carboxyl-terminal hydrolase 4 isoform X1\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"101682342 USP5; ubiquitin carboxyl-terminal hydrolase 5 isoform X1\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"101687904 USP13; ubiquitin carboxyl-terminal hydrolase 13 isoform X1\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"101672294 USP32; ubiquitin carboxyl-terminal hydrolase 32 isoform X1\tK11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6\/32 [EC:3.4.19.12]"
				},
				{
					"name":"101672974 USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X2\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"101690088 USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"101673372 USP24; ubiquitin carboxyl-terminal hydrolase 24 isoform X1\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"101694031 USP9X; probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"101687603 USP10; ubiquitin carboxyl-terminal hydrolase 10\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"101675428 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 12\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"101677526 USP46; ubiquitin carboxyl-terminal hydrolase 46 isoform X2\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"106003338 USP12; ubiquitin carboxyl-terminal hydrolase 12\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"101670282 USP14; ubiquitin carboxyl-terminal hydrolase 14 isoform X1\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"101686234 USP15; ubiquitin carboxyl-terminal hydrolase 15 isoform X1\tK21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]"
				},
				{
					"name":"101683080 USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"101692670 USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"101673730 ubiquitin carboxyl-terminal hydrolase 17-like protein 6\tK11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]"
				},
				{
					"name":"101689492 USP18; ubl carboxyl-terminal hydrolase 18 isoform X1\tK11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18\/41 [EC:3.4.19.12]"
				},
				{
					"name":"101685914 USP19; ubiquitin carboxyl-terminal hydrolase 19 isoform X1\tK11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]"
				},
				{
					"name":"101684629 USP33; ubiquitin carboxyl-terminal hydrolase 33 isoform X1\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"101693025 USP20; ubiquitin carboxyl-terminal hydrolase 20 isoform X1\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"101671112 USP21; ubiquitin carboxyl-terminal hydrolase 21\tK21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]"
				},
				{
					"name":"101680360 USP22; ubiquitin carboxyl-terminal hydrolase 22\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"101683579 USP51; ubiquitin carboxyl-terminal hydrolase 51\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"101693937 USP27X; ubiquitin carboxyl-terminal hydrolase 27\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"101679641 USP25; ubiquitin carboxyl-terminal hydrolase 25 isoform X1\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"101682701 USP26; ubiquitin carboxyl-terminal hydrolase 26\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"101684738 USP37; ubiquitin carboxyl-terminal hydrolase 37 isoform X1\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"101680038 USP28; ubiquitin carboxyl-terminal hydrolase 28 isoform X1\tK21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]"
				},
				{
					"name":"101678979 USP30; ubiquitin carboxyl-terminal hydrolase 30 isoform X1\tK11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]"
				},
				{
					"name":"101670943 USP31; ubiquitin carboxyl-terminal hydrolase 31\tK11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]"
				},
				{
					"name":"101685140 USP34; ubiquitin carboxyl-terminal hydrolase 34\tK11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]"
				},
				{
					"name":"101678711 USP35; ubiquitin carboxyl-terminal hydrolase 35\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"101682678 USP38; ubiquitin carboxyl-terminal hydrolase 38\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"101673360 USP36; ubiquitin carboxyl-terminal hydrolase 36\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"101676990 USP42; ubiquitin carboxyl-terminal hydrolase 42 isoform X1\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"101692035 USP40; ubiquitin carboxyl-terminal hydrolase 40 isoform X6\tK11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]"
				},
				{
					"name":"101681839 USP43; ubiquitin carboxyl-terminal hydrolase 43 isoform X1\tK11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]"
				},
				{
					"name":"101671905 USP44; ubiquitin carboxyl-terminal hydrolase 44\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"101678602 USP49; ubiquitin carboxyl-terminal hydrolase 49\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"101684314 USP47; ubiquitin carboxyl-terminal hydrolase 47 isoform X1\tK11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]"
				},
				{
					"name":"101690883 USP48; ubiquitin carboxyl-terminal hydrolase 48 isoform X1\tK11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]"
				},
				{
					"name":"101690361 USP50; inactive ubiquitin carboxyl-terminal hydrolase 50\tK28833 USP50; ubiquitin carboxyl-terminal hydrolase 50 [EC:3.4.19.12]"
				},
				{
					"name":"101692774 USP54; inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X1\tK27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"101669980 OTUB1; ubiquitin thioesterase OTUB1\tK09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]"
				},
				{
					"name":"101677953 OTUB2; ubiquitin thioesterase OTUB2 isoform X2\tK09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]"
				},
				{
					"name":"101679211 OTUD3; OTU domain-containing protein 3 isoform X1\tK13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"101680775 OTUD5; OTU domain-containing protein 5 isoform X2\tK12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]"
				},
				{
					"name":"101671419 OTUD6A; OTU domain-containing protein 6A\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"101671476 OTUD6B; OTU domain-containing protein 6B isoform X1\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"101676035 OTUD7A; OTU domain-containing protein 7A\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"101678863 OTUD7B; OTU domain-containing protein 7B\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"101673704 OTULIN; ubiquitin thioesterase otulin\tK18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]"
				},
				{
					"name":"101691448 TNFAIP3; tumor necrosis factor alpha-induced protein 3 isoform X2\tK11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"101670110 VCPIP1; deubiquitinating protein VCIP135\tK11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]"
				},
				{
					"name":"101691489 ZRANB1; ubiquitin thioesterase ZRANB1 isoform X1\tK11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD",
				"children":[
				{
					"name":"101684939 ATXN3; ataxin-3 isoform X1\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				},
				{
					"name":"101671464 JOSD1; josephin-1\tK15235 JOSD; josephin [EC:3.4.19.12]"
				},
				{
					"name":"101672766 JOSD2; josephin-2\tK15235 JOSD; josephin [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"101679860 FAM63B; protein FAM63B\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"101680573 FAM63A; protein FAM63A\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"101684736 FAM188B; protein FAM188B\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"101693121 FAM188A; protein FAM188A isoform X1\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"106006112 protein FAM188B2\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"101684244 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"101679453 MYSM1; histone H2A deubiquitinase MYSM1 isoform X3\tK11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]"
				},
				{
					"name":"101684010 MPND; MPN domain-containing protein\tK24173 MPND; MPN domain-containing protein"
				},
				{
					"name":"101670572 PSMD14; 26S proteasome non-ATPase regulatory subunit 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				},
				{
					"name":"101692862 STAMBP; STAM-binding protein\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"101678582 STAMBPL1; AMSH-like protease isoform X1\tK11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"PPPDE",
				"children":[
				{
					"name":"101684914 DESI2; desumoylating isopeptidase 2\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"ZUFSP",
				"children":[
				{
					"name":"101675642 ZUFSP; zinc finger with UFM1-specific peptidase domain protein\tK24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"BRISC complex",
				"children":[
				{
					"name":"101692137 FAM175B; BRISC complex subunit Abro1\tK20799 FAM175B; BRISC complex subunit Abro1"
				},
				{
					"name":"101676829 BABAM1; BRISC and BRCA1-A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
				},
				{
					"name":"101684244 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"101680577 BRE; BRCA1-A complex subunit BRE\tK12173 BRE; BRCA1-A complex subunit BRE"
				}
				]
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"101689751 SENP1; sentrin-specific protease 1 isoform X1\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"101669975 SENP2; sentrin-specific protease 2\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"101682757 sentrin-specific protease 2\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"101683192 SENP3; sentrin-specific protease 3\tK08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]"
			},
			{
				"name":"101675677 SENP5; sentrin-specific protease 5 isoform X1\tK08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]"
			},
			{
				"name":"101684604 SENP6; sentrin-specific protease 6 isoform X1\tK08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]"
			},
			{
				"name":"101670712 SENP7; sentrin-specific protease 7 isoform X1\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"101679278 SENP8; sentrin-specific protease 8\tK08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]"
			},
			{
				"name":"101688658 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X1\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"101679838 DESI1; desumoylating isopeptidase 1\tK22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]"
			},
			{
				"name":"101688747 USPL1; SUMO-specific isopeptidase USPL1\tK23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"101693822 GPS1; COP9 signalosome complex subunit 1 isoform X1\tK12175 GPS1; COP9 signalosome complex subunit 1"
				},
				{
					"name":"101690162 COPS2; COP9 signalosome complex subunit 2 isoform X2\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"101685601 COPS3; COP9 signalosome complex subunit 3 isoform X1\tK12177 COPS3; COP9 signalosome complex subunit 3"
				},
				{
					"name":"101690449 COPS4; COP9 signalosome complex subunit 4 isoform X1\tK12178 COPS4; COP9 signalosome complex subunit 4"
				},
				{
					"name":"101675696 COPS5; COP9 signalosome complex subunit 5 isoform X1\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"101677495 COPS6; COP9 signalosome complex subunit 6\tK12179 COPS6; COP9 signalosome complex subunit 6"
				},
				{
					"name":"101680151 COPS7B; COP9 signalosome complex subunit 7b\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"101687291 COPS7A; COP9 signalosome complex subunit 7a\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"101677249 COPS8; COP9 signalosome complex subunit 8\tK12181 COPS8; COP9 signalosome complex subunit 8"
				},
				{
					"name":"101694166 MYEOV2; myeloma-overexpressed gene 2 protein\tK28062 COPS9; COP9 signalosome complex subunit 9"
				}
				]
			}
			]
		}
		]
	}
	]
}