{
	"name":"msyl03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"126615349 LOC126615349; origin of replication complex subunit 1A-like\tK02603 ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"126633136 LOC126633136; origin of replication complex subunit 2\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"126628491 ORC3; origin recognition complex subunit 3 isoform X1\tK02605 ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"126607579 ORC4; origin recognition complex subunit 4\tK02606 ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"126621285 ORC5; origin recognition complex protein 5 isoform X1\tK02607 ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"126595618 ORC6; origin recognition complex protein 6 isoform X1\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"126607135 LOC126607135; origin of replication complex subunit 6-like\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"126607140 LOC126607140; origin of replication complex subunit 6-like\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"126585842 LOC126585842; CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"126620616 LOC126620616; CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"126623068 LOC126623068; CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"126589055 LOC126589055; cell division control protein 6 homolog B-like\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"126615888 LOC126615888; cell division control protein 6 homolog B-like\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"126597460 LOC126597460; DNA replication licensing factor MCM2-like\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"126607428 LOC126607428; DNA replication licensing factor MCM2-like\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"126585556 LOC126585556; DNA replication licensing factor MCM3-like\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"126624786 LOC126624786; DNA replication licensing factor MCM3-like\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"126587927 LOC126587927; DNA replication licensing factor MCM4-like\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"126624738 LOC126624738; DNA replication licensing factor MCM4-like\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"126606026 LOC126606026; DNA replication licensing factor MCM5-like isoform X1\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"126614029 LOC126614029; DNA replication licensing factor MCM5-like\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"126586584 LOC126586584; DNA replication licensing factor MCM6-like\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"126624803 LOC126624803; DNA replication licensing factor MCM6-like\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"126615135 LOC126615135; DNA replication licensing factor MCM7-like\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				},
				{
					"name":"126633114 LOC126633114; DNA replication licensing factor MCM7-like\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"126584988 LOC126584988; cyclin-A3-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126601204 LOC126601204; putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126601206 LOC126601206; putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126601408 LOC126601408; cyclin-A1-4-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126603390 LOC126603390; cyclin-A1-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126604378 LOC126604378; cyclin-A2-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126610236 LOC126610236; cyclin-A2-4-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126624381 LOC126624381; cyclin-A3-1-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126630950 LOC126630950; cyclin-A2-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126631647 LOC126631647; cyclin-A1-4-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126633381 LOC126633381; putative cyclin-A3-1 isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126633382 LOC126633382; cyclin-A3-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"126611011 LOC126611011; cell division control protein 2 homolog\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				},
				{
					"name":"126629382 LOC126629382; cell division control protein 2 homolog\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"126617779 LOC126617779; uncharacterized protein LOC126617779\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				},
				{
					"name":"126625120 LOC126625120; uncharacterized protein LOC126625120\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				},
				{
					"name":"126629741 LOC126629741; uncharacterized protein LOC126629741 isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"126611634 PSF1; partner of SLD five 1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"126623015 LOC126623015; DNA replication complex GINS protein PSF2-like\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"126628103 LOC126628103; DNA replication complex GINS protein PSF2-like isoform X1\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"126630769 LOC126630769; DNA replication complex GINS protein PSF3-like\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"126597152 LOC126597152; DNA replication complex GINS protein SLD5\tK10735 GINS4; GINS complex subunit 4"
				},
				{
					"name":"126606732 LOC126606732; DNA replication complex GINS protein SLD5-like\tK10735 GINS4; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"126616582 LOC126616582; BRCT domain-containing protein At4g02110-like isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"126632118 MEI1; transcription coactivator\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"126607633 LOC126607633; DEAD\/DEAH box RNA helicase family protein\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"126584833 LOC126584833; uncharacterized protein LOC126584833\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"126623601 LOC126623601; uncharacterized protein LOC126623601\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"126619977 MCM8; minichromosome maintenance 8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"126620897 MCM9; minichromosome maintenance 9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"126584911 MCM10; minichromosome maintenance 10\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"126629350 LOC126629350; mini-chromosome maintenance complex-binding protein-like\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				},
				{
					"name":"126632241 LOC126632241; mini-chromosome maintenance complex-binding protein-like\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"126604128 LOC126604128; DNA polymerase alpha catalytic subunit-like\tK02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"126596398 LOC126596398; uncharacterized protein LOC126596398\tK02321 POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"126599541 LOC126599541; uncharacterized protein LOC126599541 isoform X1\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"126627375 POLA3; DNA primase POLA3\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"126596518 EMB2813; DNA primase, large subunit family isoform X1\tK02685 PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"126589850 LOC126589850; DNA polymerase epsilon catalytic subunit A-like isoform X1\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"126615148 LOC126615148; DNA polymerase epsilon catalytic subunit A-like\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"126626323 DPB2; DNA polymerase epsilon subunit B2\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"126588287 NF-YB11; nuclear factor Y, subunit B11\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"126620807 LOC126620807; DNA polymerase delta subunit 1\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"126592666 LOC126592666; DNA polymerase delta small subunit-like\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"126600734 LOC126600734; DNA polymerase delta small subunit-like isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"126589961 LOC126589961; uncharacterized protein LOC126589961\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"126614613 LOC126614613; uncharacterized protein LOC126614613\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"126627639 POLD4; polymerase delta 4\tK03505 POLD4; DNA polymerase delta subunit 4"
				},
				{
					"name":"126629215 LOC126629215; uncharacterized protein LOC126629215\tK03505 POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)"
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"126599745 LOC126599745; replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"126602155 LOC126602155; replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"126606558 LOC126606558; replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"126625787 LOC126625787; replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"126627193 LOC126627193; replication factor-A protein 1-like protein\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"126596924 LOC126596924; replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"126604324 LOC126604324; replication protein A 32 kDa subunit A-like\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"126593753 LOC126593753; replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3"
				},
				{
					"name":"126600719 LOC126600719; replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"126623093 LOC126623093; replication factor C subunit 1-like isoform X1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"126628274 LOC126628274; replication factor C subunit 1-like\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"126605760 EMB1968; ATPase family associated with various cellular activities (AAA)\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"126619561 RFC2; replication factor C 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"126593437 LOC126593437; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126601157 LOC126601157; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126602429 LOC126602429; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126604787 LOC126604787; uncharacterized protein LOC126604787\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126619301 LOC126619301; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126630482 LOC126630482; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126632809 LOC126632809; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"126582633 LOC126582633; ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"126604282 LOC126604282; ribonuclease H2 subunit B\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"126585371 LOC126585371; uncharacterized protein LOC126585371 isoform X1\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				},
				{
					"name":"126621199 LOC126621199; uncharacterized protein LOC126621199 isoform X1\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"126589135 LOC126589135; DNA sliding clamp PCNA-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"126614914 LOC126614914; DNA sliding clamp PCNA\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"126628735 LOC126628735; DNA sliding clamp PCNA-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"126627724 EMB2411; DNA replication helicase\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"126619535 LOC126619535; 5'-3' exonuclease family protein isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"126586006 LOC126586006; 5'-3' exonuclease family protein isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"126598656 LOC126598656; 5'-3' exonuclease family protein\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"126599546 LOC126599546; SNF2 domain-containing protein \/ helicase domain-containing protein \/ HNH endonuclease domain-containing protein\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"126588919 LOC126588919; DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"126615853 LOC126615853; DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"126604222 LOC126604222; P-loop containing nucleoside triphosphate hydrolases superfamily protein\tK26118 ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"126588443 LOC126588443; DNA (cytosine-5)-methyltransferase CMT3-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"126604995 LOC126604995; DNA (cytosine-5)-methyltransferase 4-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"126609277 LOC126609277; DNA (cytosine-5)-methyltransferase 1-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"126615636 LOC126615636; DNA (cytosine-5)-methyltransferase CMT3\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"126625261 LOC126625261; DNA (cytosine-5)-methyltransferase CMT2-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"126593285 LOC126593285; PWWP domain-containing protein 1-like\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				},
				{
					"name":"126619004 LOC126619004; tudor\/PWWP\/MBT superfamily protein\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"126581972 LOC126581972; G2\/mitotic-specific cyclin-2-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126584359 LOC126584359; G2\/mitotic-specific cyclin-2-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126586752 CYCB3;1; cyclin b3;1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126588500 LOC126588500; G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126592967 LOC126592967; G2\/mitotic-specific cyclin S13-6-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126597649 SDS; cyclin family protein\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126602354 LOC126602354; G2\/mitotic-specific cyclin-2-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126616141 LOC126616141; G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126616248 LOC126616248; G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126616250 LOC126616250; G2\/mitotic-specific cyclin S13-7-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"126621302 LOC126621302; G2\/mitotic-specific cyclin-2-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex"
				},
				{
					"name":"TERB1-TERB2-MAJIN complex"
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"126615979 STN1; nucleic acid-binding, OB-fold-like protein\tK23312 STN1; CST complex subunit STN1"
					},
					{
						"name":"126592009 LOC126592009; CST complex subunit TEN1-like\tK23313 TEN1; CST complex subunit TEN1"
					},
					{
						"name":"126618960 LOC126618960; CST complex subunit TEN1-like\tK23313 TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)"
				},
				{
					"name":"RIF proteins"
				},
				{
					"name":"SIR proteins"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"126628608 TERT; telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"126585595 LOC126585595; putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"126623171 LOC126623171; putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"126599400 LOC126599400; H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"126627172 LOC126627172; H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"126585408 LOC126585408; H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"126620914 LOC126620914; H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"126607125 LOC126607125; H\/ACA ribonucleoprotein complex subunit 4-like isoform X1\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"126625371 LOC126625371; H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"126628608 TERT; telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"126626149 LOC126626149; uncharacterized protein LOC126626149\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"126591543 LOC126591543; small nuclear ribonucleoprotein SmD1a\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"126617337 LOC126617337; small nuclear ribonucleoprotein SmD1a\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"126605564 LOC126605564; uncharacterized protein LOC126605564\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"126613936 LOC126613936; uncharacterized protein LOC126613936\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"126605993 LOC126605993; small nuclear ribonucleoprotein SmD3b\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"126631084 LOC126631084; small nuclear ribonucleoprotein SmD3b-like\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"126597408 LOC126597408; uncharacterized protein LOC126597408 isoform X1\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"126594787 LOC126594787; putative small nuclear ribonucleoprotein F isoform X1\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"126608434 LOC126608434; putative small nuclear ribonucleoprotein F isoform X1\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"126632864 LOC126632864; putative small nuclear ribonucleoprotein F isoform X1\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"126594429 LOC126594429; putative small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"126598513 LOC126598513; putative small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"126605760 EMB1968; ATPase family associated with various cellular activities (AAA)\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"126619561 RFC2; replication factor C 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"126593437 LOC126593437; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126601157 LOC126601157; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126602429 LOC126602429; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126604787 LOC126604787; uncharacterized protein LOC126604787\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126619301 LOC126619301; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126630482 LOC126630482; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"126632809 LOC126632809; replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"126590739 LOC126590739; double-strand break repair protein MRE11-like\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"126614933 LOC126614933; double-strand break repair protein MRE11-like\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"126618701 RAD50; DNA repair-recombination protein (RAD50)\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"126591329 NBS1; nijmegen breakage syndrome 1\tK10867 NBN; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"126626183 ATM; serine\/Threonine-kinase ATM-like protein isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"126618995 RECQSIM; RECQ helicase SIM\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
				},
				{
					"name":"126582506 LOC126582506; ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"126607216 RECQL3; DEAD\/DEAH box RNA helicase family protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"126630767 LOC126630767; ATP-dependent DNA helicase Q-like 4A isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"126625701 UVH1; restriction endonuclease, type II-like superfamily protein\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"126586308 LOC126586308; poly [ADP-ribose] polymerase 1-like\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"126623405 LOC126623405; poly [ADP-ribose] polymerase 1-like\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"126614786 LOC126614786; poly [ADP-ribose] polymerase 2-like isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"126614788 LOC126614788; poly [ADP-ribose] polymerase 2-like isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"126614789 LOC126614789; poly [ADP-ribose] polymerase 2-like isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"126598903 LOC126598903; D111\/G-patch domain-containing protein\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"126625013 LOC126625013; G-patch domain-containing protein 1-like isoform X1\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"126612639 LOC126612639; RAD3-like DNA-binding helicase protein isoform X1\tK11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"126598429 EMB2423; telomere length regulation TEL2 family protein\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"126605484 LOC126605484; uncharacterized protein LOC126605484 isoform X1\tK11138 RIF1; telomere-associated protein RIF1"
				},
				{
					"name":"126589373 LOC126589373; transcription factor Pur-alpha 1-like isoform X1\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"126615882 LOC126615882; transcription factor Pur-alpha 1-like isoform X1\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"126587839 LOC126587839; transducin\/WD40 repeat-like superfamily protein\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"126620737 LOC126620737; uncharacterized protein LOC126620737\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"126620197 LOC126620197; uncharacterized protein LOC126620197\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"126629117 LOC126629117; uncharacterized protein LOC126629117\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"126603430 LOC126603430; RTF2 RING-finger protein\tK25186 RTF2; replication termination factor 2"
				},
				{
					"name":"126613991 LOC126613991; uncharacterized protein LOC126613991\tK25186 RTF2; replication termination factor 2"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"126596118 LOC126596118; DNA topoisomerase 1 beta-like\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"126606748 LOC126606748; DNA topoisomerase 1 alpha-like isoform X1\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"126588976 LOC126588976; DNA topoisomerase 2-like\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"126588978 LOC126588978; DNA topoisomerase 2-like\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"126613455 LOC126613455; DNA topoisomerase 2-like isoform X1\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"126628370 LOC126628370; DNA topoisomerase 2-like\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"126601912 TOP3A; topoisomerase 3alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"126618884 LOC126618884; DNA topoisomerase, type IA, core isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"126599440 LOC126599440; single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"126626822 LOC126626822; single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)"
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"126588946 LOC126588946; DNA polymerase I B, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases"
				},
				{
					"name":"D-family DNA polymerases"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"126627724 EMB2411; DNA replication helicase\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"126619535 LOC126619535; 5'-3' exonuclease family protein isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"126588919 LOC126588919; DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"126615853 LOC126615853; DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein"
			},
			{
				"name":"DNA methylation enzymes"
			},
			{
				"name":"Prevention of re-replication factors"
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"126582807 LOC126582807; DNA gyrase subunit A, chloroplastic\/mitochondrial-like\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"126630768 LOC126630768; DNA gyrase subunit A, chloroplastic\/mitochondrial-like\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"126593609 LOC126593609; DNA gyrase subunit B, chloroplastic\/mitochondrial-like isoform X1\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"126599424 LOC126599424; DNA gyrase subunit B, chloroplastic\/mitochondrial-like\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"126616133 TOP6B; topoisomerase 6 subunit B\tK03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]"
			}
			]
		}
		]
	}
	]
}
