{
	"name":"mtv03016",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P"
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"RVBD_2407 ribonuclease Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"RVBD_3907c poly(A) polymerase PcnA\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonuclease complex"
			},
			{
				"name":"tRNA splicing ligase complex",
				"children":[
				{
					"name":"RVBD_2631 hypothetical protein\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				},
				{
					"name":"RVBD_2630 hypothetical protein\tK24956 ZBTB8OS; protein archease"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			},
			{
				"name":"tRNA import factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"RVBD_2992c glutamyl-tRNA synthetase GltS\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"RVBD_2845c prolyl-tRNA synthetase ProS\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"RVBD_1536 isoleucyl-tRNA synthetase IleS\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"RVBD_0041 leucyl-tRNA synthetase LeuS\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"RVBD_1007c methionyl-tRNA synthetase MetS\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"RVBD_1292 arginyl-tRNA synthetase ArgS\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"RVBD_1640c lysyl-tRNA synthetase 2 LysX\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"RVBD_3598c lysyl-tRNA synthetase 1 LysS\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"RVBD_2572c aspartyl-tRNA synthetase AspS\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"RVBD_2555c alanyl-tRNA synthetase AlaS\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"RVBD_2357c glycyl-tRNA synthetase GlyS\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"RVBD_2614c threonyl-tRNA synthetase ThrS\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"RVBD_3834c seryl-tRNA synthetase SerS\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"RVBD_3580c cysteinyl-tRNA synthetase CysS1\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"RVBD_2448c valyl-tRNA synthase ValS\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"RVBD_2580c histidyl-tRNA synthetase HisS\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"RVBD_1649 phenylalanyl-tRNA synthetase alpha chain PheS\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"RVBD_1650 phenylalanyl-tRNA synthetase beta chain PheT\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"RVBD_1689 tyrosyl-tRNA synthase TyrS\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"RVBD_3336c tryptophanyl-tRNA synthetase TrpS\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"RVBD_1897c d-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				}
				]
			},
			{
				"name":"AARS associated factors",
				"children":[
				{
					"name":"RVBD_1262c hypothetical protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases"
			},
			{
				"name":"Dihydorouridine synthases"
			},
			{
				"name":"Methylthiotransferase",
				"children":[
				{
					"name":"RVBD_2733c (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"RVBD_2118c RNA methyltransferase\tK07442 TRM61; tRNA (adenine57-N1\/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]"
				},
				{
					"name":"RVBD_0208c methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"RVBD_3455c tRNA pseudouridine synthase A TruA\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"RVBD_2793c tRNA pseudouridine synthase B TruB\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"RVBD_3025c cysteine desulfurase LscS\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Elongator complex"
			},
			{
				"name":"Elongator related proteins"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"RVBD_1301 Sua5\/YciO\/YrdC\/YwlC family protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"RVBD_2727c tRNA delta(2)-isopentenylpyrophosphate transferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"TRAMP complex"
			},
			{
				"name":"Rapid tRNA decay (RTD) pathway factors",
				"children":[
				{
					"name":"RVBD_2131c monophosphatase CysQ\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				}
				]
			},
			{
				"name":"Other tRNA degradation factors"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"RVBD_3923c ribonuclease P protein component RnpA\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"RVBD_2407 ribonuclease Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"RVBD_1340 ribonuclease RphA\tK00989 rph; ribonuclease PH [EC:2.7.7.56]"
				},
				{
					"name":"RVBD_2681 ribonuclease D\tK03684 rnd; ribonuclease D [EC:3.1.13.5]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"RVBD_3907c poly(A) polymerase PcnA\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonucleases"
			},
			{
				"name":"tRNA splicing ligases",
				"children":[
				{
					"name":"RVBD_2631 hypothetical protein\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors",
				"children":[
				{
					"name":"RVBD_2477c ChvD family ATP-binding cassette protein\tK06020 ettA; energy-dependent translational throttle protein EttA"
				}
				]
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"RVBD_0041 leucyl-tRNA synthetase LeuS\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"RVBD_2845c prolyl-tRNA synthetase ProS\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"RVBD_1689 tyrosyl-tRNA synthase TyrS\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"RVBD_3336c tryptophanyl-tRNA synthetase TrpS\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"RVBD_2614c threonyl-tRNA synthetase ThrS\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"RVBD_1536 isoleucyl-tRNA synthetase IleS\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"RVBD_1640c lysyl-tRNA synthetase 2 LysX\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"RVBD_3598c lysyl-tRNA synthetase 1 LysS\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"RVBD_2555c alanyl-tRNA synthetase AlaS\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"RVBD_2448c valyl-tRNA synthase ValS\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"RVBD_1007c methionyl-tRNA synthetase MetS\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"RVBD_3834c seryl-tRNA synthetase SerS\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"RVBD_2572c aspartyl-tRNA synthetase AspS\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"RVBD_3580c cysteinyl-tRNA synthetase CysS1\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"RVBD_2992c glutamyl-tRNA synthetase GltS\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"RVBD_1292 arginyl-tRNA synthetase ArgS\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"RVBD_1649 phenylalanyl-tRNA synthetase alpha chain PheS\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"RVBD_1650 phenylalanyl-tRNA synthetase beta chain PheT\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"RVBD_2580c histidyl-tRNA synthetase HisS\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"RVBD_1897c d-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"RVBD_3224B hypothetical protein\tK03976 ybaK; Cys-tRNA(Pro)\/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases",
				"children":[
				{
					"name":"RVBD_3752c cytidine\/deoxycytidylate deaminase\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]"
				}
				]
			},
			{
				"name":"Dihydorouridine synthases"
			},
			{
				"name":"Methylthiotransferases",
				"children":[
				{
					"name":"RVBD_2733c (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"RVBD_0208c methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"RVBD_2906c tRNA (guanine-N1)-methyltransferase TrmD\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"RVBD_3366 tRNA\/rRNA methylase SpoU\tK03216 trmL; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]"
				},
				{
					"name":"RVBD_1644 23S rRNA methyltransferase TsnR\tK03437 spoU; RNA methyltransferase, TrmH family"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"RVBD_3455c tRNA pseudouridine synthase A TruA\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"RVBD_2793c tRNA pseudouridine synthase B TruB\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"RVBD_3300c hypothetical protein\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"RVBD_3024c tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TrmU\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"RVBD_3025c cysteine desulfurase LscS\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"RVBD_0811c folate-binding protein YgfZ\tK06980 ygfZ; tRNA-modifying protein YgfZ"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"RVBD_2727c tRNA delta(2)-isopentenylpyrophosphate transferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"RVBD_3625c cell cycle protein MesJ\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"RVBD_3421c universal bacterial protein YeaZ\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"RVBD_1301 Sua5\/YciO\/YrdC\/YwlC family protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"RVBD_3419c O-sialoglycoprotein endopeptidase Gcp\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"RVBD_3422c ATPase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"RVBD_2783c polyribonucleotide nucleotidyltransferase GpsI\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
			}
			]
		}
		]
	}
	]
}