{
	"name":"mzi03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs",
				"children":[
				{
					"name":"HWN40_12535 NOP58 family protein\tK14564 NOP56; nucleolar protein 56"
				}
				]
			},
			{
				"name":"Box H\/ACA snoRNPs",
				"children":[
				{
					"name":"HWN40_02415 RNA-protein complex protein Nop10\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
				}
				]
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins",
				"children":[
				{
					"name":"HWN40_09040 rRNA maturation protein\tK14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4"
				}
				]
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase"
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles",
				"children":[
				{
					"name":"HWN40_13110 RNA-processing protein\tK06961 KRR1; ribosomal RNA assembly protein"
				}
				]
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases",
				"children":[
				{
					"name":"HWN40_13105 serine protein kinase RIO\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
				},
				{
					"name":"HWN40_04375 serine\/threonine protein kinase\tK07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Export and cytoplasmic maturation factors",
				"children":[
				{
					"name":"HWN40_12035 AAA family ATPase\tK18532 AK6; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"HWN40_04435 DUF367 family protein\tK09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]"
				}
				]
			},
			{
				"name":"Other pre-40S particles",
				"children":[
				{
					"name":"HWN40_12825 ribosome biogenesis\/translation initiation ATPase RLI\tK06174 ABCE1; ATP-binding cassette, sub-family E, member 1"
				}
				]
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases",
				"children":[
				{
					"name":"HWN40_00610 NOG1 family protein\tK06943 NOG1; nucleolar GTP-binding protein"
				}
				]
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"RNase MRP",
					"children":[
					{
						"name":"HWN40_02885 ribonuclease P protein component 1\tK03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]"
					},
					{
						"name":"HWN40_09080 ribonuclease P\tK03537 POP5; ribonuclease P\/MRP protein subunit POP5 [EC:3.1.26.5]"
					},
					{
						"name":"HWN40_09085 ribonuclease P protein component 3\tK03539 RPP1; ribonuclease P\/MRP protein subunit RPP1 [EC:3.1.26.5]"
					}
					]
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors",
				"children":[
				{
					"name":"HWN40_05015 translation initiation factor IF-6\tK03264 EIF6; translation initiation factor 6"
				},
				{
					"name":"HWN40_08285 NMD protein affecting ribosome stability and mRNA decay\tK07562 NMD3; 60S ribosomal export protein NMD3"
				},
				{
					"name":"HWN40_09070 ribosome assembly factor SBDS\tK14574 SDO1; ribosome maturation protein SDO1"
				}
				]
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins",
				"children":[
				{
					"name":"HWN40_02200 CDC48 family AAA ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"HWN40_11790 CDC48 family AAA ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				}
				]
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"HWN40_00635 GTP-binding protein\tK03595 era; GTPase"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs",
				"children":[
				{
					"name":"HWN40_12535 NOP58 family protein\tK14564 NOP56; nucleolar protein 56"
				},
				{
					"name":"HWN40_12530 fibrillarin-like rRNA\/tRNA 2'-O-methyltransferase\tK04795 flpA; fibrillarin-like pre-rRNA processing protein"
				},
				{
					"name":"HWN40_08390 rpl7ae; 50S ribosomal protein L7Ae\tK02936 RP-L7Ae; large subunit ribosomal protein L7Ae"
				}
				]
			},
			{
				"name":"Box H\/ACA snoRNPs",
				"children":[
				{
					"name":"HWN40_04205 H\/ACA RNA-protein complex protein Gar1\tK07569 gar1; RNA-binding protein"
				},
				{
					"name":"HWN40_02415 RNA-protein complex protein Nop10\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
				}
				]
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"HWN40_03430 NusA-like transcription termination signal-binding factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"HWN40_08790 16S ribosomal RNA methyltransferase A\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"HWN40_07810 methyltransferase domain-containing protein\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"HWN40_03580 TRAM domain-containing protein\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"HWN40_07810 methyltransferase domain-containing protein\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"HWN40_01310 rimI; ribosomal protein S18-alanine N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"HWN40_06160 GNAT family N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"HWN40_12385 rimI; ribosomal protein S18-alanine N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"HWN40_07510 rimK; 30S ribosomal protein S6--L-glutamate ligase\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			}
			]
		},
		{
			"name":"rRNA processing factors"
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"HWN40_07035 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"HWN40_08760 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"HWN40_00635 GTP-binding protein\tK03595 era; GTPase"
			},
			{
				"name":"HWN40_07545 rsgA; ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"HWN40_03785 hflX; GTPase HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"HWN40_08355 threonylcarbamoyl-AMP synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"HWN40_12270 YhbY family RNA-binding protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"HWN40_12395 redox-regulated ATPase YchF\tK06942 ychF; ribosome-binding ATPase"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}