{
	"name":"ncr03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"NCU03971 mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"NCU09778 cdc28; cdc28-like\tK04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22]"
					},
					{
						"name":"NCU03659 prk-3; protein kinase-3\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"NCU06260 mRNA-capping enzyme subunit alpha\tK00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"NCU04187 cap binding protein\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"NCU00210 nuclear cap binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"NCU09014 cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"NCU06314 hypothetical protein\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"NCU01696 mRNA cleavage factor complex component Pcf11\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"NCU02082 cft-1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"NCU06869 cleavage and polyadenylylation specificity factor\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"NCU03479 endoribonuclease ysh-1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"NCU08353 mRNA 3'-end-processing protein yth-1\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"NCU07654 pre-mRNA polyadenylation factor fip-1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"NCU06718 zinc knuckle domain-containing protein\tK15541 MPE1; protein MPE1"
					},
					{
						"name":"NCU00037 polyadenylation factor subunit 2\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"NCU07885 WD repeat containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"NCU00043 pph-3; protein phosphatase-3\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"NCU07489 pzl-1; phosphatase-Z-like-1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"NCU03114 SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"NCU03311 polyadenylation factor subunit CstF64\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"NCU09435 mRNA 3'-end-processing protein RNA-14\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"NCU09128 hypothetical protein\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"NCU02508 hypothetical protein\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"NCU03625 small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"NCU06354 small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"NCU01614 hypothetical protein\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"NCU09880 small nuclear ribonucleoprotein SmG\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"NCU06869 cleavage and polyadenylylation specificity factor\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"NCU03479 endoribonuclease ysh-1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"NCU03311 polyadenylation factor subunit CstF64\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"NCU09128 hypothetical protein\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"NCU03838 transcription elongation factor spt-4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"NCU06929 transcription elongation factor spt-5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"NCU11362 DUF890 domain-containing protein\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"NCU08983 un-17; unknown-17\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing"
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"NCU03839 APF1\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"NCU02800 arsenite resistance protein Ars2\tK27103 SRRT; serrate RNA effector molecule"
				},
				{
					"name":"NCU16397 nuclear polyadenylated RNA-binding protein Nab2\tK23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"NCU03226 Y14 protein\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"NCU04405 mago nashi protein\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"NCU01793 RNA binding domain-containing protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"NCU07421 hypothetical protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"NCU09076 ATP-dependent RNA helicase\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"NCU01234 eukaryotic initiation factor 4A-12\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"NCU03932 hypothetical protein\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"NCU00159 Sin3-associated polypeptide Sap18\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"NCU09901 hypothetical protein\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"NCU03285 hypothetical protein\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"NCU07865 THO complex subunit Tho1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"NCU07002 THO complex component\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"NCU02753 WD repeat-containing protein\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"NCU01793 RNA binding domain-containing protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"NCU07421 hypothetical protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"NCU03239 hypothetical protein\tK13174 THOC5; THO complex subunit 5"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"NCU16773 hypothetical protein\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"NCU07913 hypothetical protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"NCU09871 centrin 3\tK16466 CETN3; centrin-3"
					},
					{
						"name":"NCU01288 hypothetical protein\tK23719 SAC3; nuclear mRNA export protein SAC3"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"NCU04059 hypothetical protein\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"NCU04288 Poly(A)+ RNA export protein\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"NCU04063 protein transporter sec-13\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"NCU02473 nucleoporin Nup44\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"NCU02808 hypothetical protein\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"NCU01702 nuclear pore protein\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"NCU04784 hypothetical protein\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"NCU09814 hypothetical protein\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"NCU04007 hypothetical protein\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"NCU00199 hypothetical protein\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"NCU04463 non-repetitive nucleoporin\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"NCU02742 hypothetical protein\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"NCU00273 hypothetical protein\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"NCU07655 hypothetical protein\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"NCU06776 hypothetical protein\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"NCU04376 hypothetical protein\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"NCU08604 hypothetical protein\tK18715 NUP159; nucleoporin NUP159"
					},
					{
						"name":"NCU06894 hypothetical protein\tK18716 NUP42; nucleoporin NUP42"
					},
					{
						"name":"NCU00209 hypothetical protein\tK18719 NUP82; nucleoporin NUP82"
					},
					{
						"name":"NCU09871 centrin 3\tK16466 CETN3; centrin-3"
					},
					{
						"name":"NCU01198 gle-1; gle-1 protein\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"NCU09317 hypothetical protein\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"NCU03631 hypothetical protein\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					},
					{
						"name":"NCU06674 hypothetical protein\tK18724 POM34; nucleoporin POM34"
					},
					{
						"name":"NCU10747 hypothetical protein\tK18725 POM152; nucleoporin POM152"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"NCU09269 ran; ran-like\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"NCU01928 UBX domain-containing protein\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"NCU00018 cell division control protein Cdc48\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"NCU01820 exportin-1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"NCU03207 ran GTPase activating protein 1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"NCU04759 ntf2; nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"NCU02076 eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"NCU09546 translation initiation factor eIF4E3\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"NCU07420 eIF4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"NCU07868 hypothetical protein\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"NCU00457 translation initiation factor 4B\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"NCU01369 ATP-dependent RNA helicase ded-1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"NCU09093 DEAD box RNA helicase-PL10B\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"NCU09657 hypothetical protein\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"NCU04799 polyadenylate-binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"NCU01857 DEAD\/DEAH box RNA helicase\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"NCU08267 activating signal cointegrator 1 complex subunit 3\tK18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6]"
					},
					{
						"name":"NCU08678 translation machinery-associated protein 20\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"NCU02984 translation machinery-associated protein 22\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex"
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"NCU03232 RNA binding protein Pym\tK14294 WIBG; partner of Y14 and mago"
					},
					{
						"name":"NCU17030 heterogeneous nuclear ribonucleoprotein HRP1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"NCU03981 elongation factor Tu GTP binding domain-containing protein\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"NCU09161 translation factor pelota\tK06965 PELO; protein pelota"
					},
					{
						"name":"NCU03946 polyadenylate-binding protein 2\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"NCU01160 ATP-dependent RNA helicase dbp-5\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"NCU08036 pre-mRNA-splicing factor syf-1\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"NCU11259 hypothetical protein\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"NCU03001 hypothetical protein\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"NCU05513 hypothetical protein\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"NCU06594 SAC3\/GANP domain-containing protein\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					},
					{
						"name":"NCU02404 RNP domain-containing protein\tK28506 GBP2; serine\/arginine (SR)-type shuttling mRNA binding protein"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"NCU00410 eukaryotic release factor 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"NCU04790 eukaryotic peptide chain release factor GTP-binding subunit\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"NCU04242 prd-6; period-6\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"NCU05267 nonsense-mediated mRNA decay factor\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"NCU03435 hypothetical protein\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"NCU06630 pph-1; protein phosphatase-1\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"NCU00488 protein phosphatase PP2A regulatory subunit A\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"NCU09377 rgb-1; B-regulatory subunit-1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"NCU03786 serine\/threonine protein phosphatase 2A\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"NCU09657 hypothetical protein\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"NCU09513 GTP-binding protein 1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"NCU09380 pumilio domain-containing protein\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"NCU06251 KH domain RNA-binding protein\tK18738 HEK; heterogeneous nuclear rnp K-like protein"
					},
					{
						"name":"NCU09237 KH domain RNA binding protein\tK18738 HEK; heterogeneous nuclear rnp K-like protein"
					},
					{
						"name":"NCU01440 myosin-2\tK10357 MYO5; myosin V"
					},
					{
						"name":"NCU07036 hypothetical protein\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals"
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"NCU09352 far upstream element-binding protein 2\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"NCU02003 tef-1; translation elongation factor-1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"NCU03826 elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"NCU10521 gst-4; glutathione S-transferase-4\tK03233 EEF1G; elongation factor 1-gamma"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"NCU01197 gul-1; gulliver-1\tK18748 SSD1; protein SSD1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"NCU06678 exonuclease Kem1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"NCU09434 sms-2; suppressor of meiotic silencing-2\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"NCU02076 eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"NCU09546 translation initiation factor eIF4E3\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"NCU04242 prd-6; period-6\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"NCU01369 ATP-dependent RNA helicase ded-1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"NCU09093 DEAD box RNA helicase-PL10B\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"NCU06149 ATP-dependent RNA helicase dhh-1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"NCU03366 hypothetical protein\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"NCU09159 hypothetical protein\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"NCU03690 importin beta-2 subunit\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"NCU00682 pkac-2; protein kinase A catalytic subunit-2\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"NCU06240 pkac-1; protein kinase A catalytic subunit-1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"NCU02720 hypothetical protein\tK18757 LARP1; la-related protein 1"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"NCU07889 hypothetical protein\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"NCU01601 hypothetical protein\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"NCU07382 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"NCU09512 U6 small nuclear ribonucleoprotein\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"NCU07683 small nuclear ribonucleoprotein\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"NCU03766 small nuclear ribonucleoprotein\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"NCU10352 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"NCU01930 U6 snRNP-associated protein Lsm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"NCU03085 small nuclear ribonucleoprotein Lsm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"NCU01440 myosin-2\tK10357 MYO5; myosin V"
					},
					{
						"name":"NCU09132 tba-1; tubulin alpha-1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"NCU09468 tba-2; tubulin alpha-2\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"NCU04766 Ccr4-Not transcription complex subunit\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"NCU11372 hypothetical protein\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"NCU03855 CCR4-NOT transcription complex\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"NCU04073 hypothetical protein\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"NCU07779 ccr4; glucose-repressible alcohol dehydrogenase transcriptional effector\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"NCU09001 CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"NCU10733 PAB-dependent poly(A)-specific ribonuclease subunit pan-2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"NCU01929 PAB-dependent poly(A)-specific ribonuclease subunit pan-3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"NCU06540 topisomerase II associated protein\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"NCU00427 hypothetical protein\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"NCU05267 nonsense-mediated mRNA decay factor\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"NCU03435 hypothetical protein\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"NCU02661 DNA-directed RNA polymerase II polypeptide\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"NCU07874 nuclear and cytoplasmic polyadenylated RNA-binding protein pub1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"NCU04799 polyadenylate-binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"NCU07574 hypothetical protein\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"NCU06099 hypothetical protein\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"NCU02208 un-10; unknown-10\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"NCU07420 eIF4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"NCU01234 eukaryotic initiation factor 4A-12\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"NCU00457 translation initiation factor 4B\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"NCU07868 hypothetical protein\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"NCU05810 cpc-2; cross pathway control-2\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"NCU09317 hypothetical protein\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"NCU01525 hda-1; histone deacetylase-1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"NCU07889 hypothetical protein\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"NCU06149 ATP-dependent RNA helicase dhh-1\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"NCU00427 hypothetical protein\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"NCU06540 topisomerase II associated protein\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"NCU01601 hypothetical protein\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"NCU07382 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"NCU09512 U6 small nuclear ribonucleoprotein\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"NCU07683 small nuclear ribonucleoprotein\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"NCU03766 small nuclear ribonucleoprotein\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"NCU10352 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"NCU01930 U6 snRNP-associated protein Lsm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"NCU03085 small nuclear ribonucleoprotein Lsm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"NCU06678 exonuclease Kem1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"NCU01643 5'-3' exoribonuclease 2\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"NCU06998 scavenger mRNA decapping enzyme\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"NCU04155 exosome component 1\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"NCU04009 exosome complex exonuclease Rrp4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"NCU00693 exosome complex exonuclease RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"NCU00812 exosome complex exonuclease RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"NCU03268 hypothetical protein\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"NCU08026 3' exoribonuclease\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"NCU01806 3' exoribonuclease\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"NCU03159 3' exoribonuclease\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"NCU00334 3' exoribonuclease\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"NCU03065 mitotic control protein dis3\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"NCU02256 exosome complex exonuclease Rrp6\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"NCU16328 hypothetical protein\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"NCU04472 DEAD\/DEAH box helicase\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"NCU05588 topoisomerase TRF4\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"NCU04617 hypothetical protein\tK12597 AIR1_2; protein AIR1\/2"
					},
					{
						"name":"NCU03363 frh; FRQ-interacting RNA helicase\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"NCU01857 DEAD\/DEAH box RNA helicase\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"NCU09438 translation repressor\/antiviral protein Ski3\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"NCU03517 Ski8\tK12601 SKI8; superkiller protein 8"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"NCU07779 ccr4; glucose-repressible alcohol dehydrogenase transcriptional effector\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"NCU04766 Ccr4-Not transcription complex subunit\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"NCU11372 hypothetical protein\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"NCU03855 CCR4-NOT transcription complex\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"NCU04073 hypothetical protein\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"NCU09001 CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"NCU07071 cell differentiation protein rcd1\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"NCU04097 ABC transporter\tK12608 CAF16; CCR4-NOT complex subunit CAF16"
					},
					{
						"name":"NCU02750 PH domain-containing protein\tK12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"NCU10733 PAB-dependent poly(A)-specific ribonuclease subunit pan-2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"NCU01929 PAB-dependent poly(A)-specific ribonuclease subunit pan-3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"NCU07559 hypothetical protein\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"NCU06998 scavenger mRNA decapping enzyme\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"NCU00120 hypothetical protein\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"NCU00311 VTS1\tK27407 VTS1; RNA-binding protein VTS1"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"NCU01762 nucleolar RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"NCU16377 oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"NCU01870 Eno3 protein\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"NCU10042 emp-7; embden-meyerhof pathway-7\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"NCU00629 emp-3; embden-meyerhof pathway-3\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"NCU08693 hsp70-5; heat shock protein 70-5\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"NCU01589 hsp60; heat shock protein 60\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"NCU04009 exosome complex exonuclease Rrp4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"NCU04155 exosome component 1\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"NCU00812 exosome complex exonuclease RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"NCU01806 3' exoribonuclease\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}