{
	"name":"ncs03110",
	"children":[
	{
		"name":"Heat shock proteins",
		"children":[
		{
			"name":"HSP110",
			"children":[
			{
				"name":"NCAS_0B01860 NCAS0B01860; adenyl-nucleotide exchange factor SSE2\tK09485 HSP110; heat shock protein 110kDa"
			},
			{
				"name":"NCAS_0C01870 NCAS0C01870; adenyl-nucleotide exchange factor SSE1\tK09485 HSP110; heat shock protein 110kDa"
			},
			{
				"name":"NCAS_0H03240 NCAS0H03240; Hsp70 family chaperone LHS1\tK09486 HYOU1; hypoxia up-regulated 1"
			}
			]
		},
		{
			"name":"HSP100",
			"children":[
			{
				"name":"NCAS_0A02890 NCAS0A02890; chaperone ATPase HSP104\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			},
			{
				"name":"NCAS_0A08040 NCAS0A08040; chaperone ATPase HSP78\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			},
			{
				"name":"NCAS_0H01380 NCAS0H01380; uncharacterized protein\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
			}
			]
		},
		{
			"name":"HSP90",
			"children":[
			{
				"name":"NCAS_0D03870 NCAS0D03870; Hsp90 family chaperone HSC82\tK04079 HSP90A; molecular chaperone HtpG"
			}
			]
		},
		{
			"name":"HSP70 \/ DNAK",
			"children":[
			{
				"name":"NCAS_0A14440 NCAS0A14440; uncharacterized protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"NCAS_0C05760 NCAS0C05760; Hsp70 family chaperone SSA2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"NCAS_0D00240 NCAS0D00240; Hsp70 family ATPase SSB1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"NCAS_0E02580 NCAS0E02580; Hsp70 family ATPase SSA3\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"NCAS_0G01560 NCAS0G01560; Hsp70 family ATPase SSB2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"NCAS_0A01220 NCAS0A01220; Hsp70 family ATPase KAR2\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
			},
			{
				"name":"NCAS_0A08260 NCAS0A08260; Hsp70 family ATPase SSC1\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"NCAS_0J01260 NCAS0J01260; Hsp70 family ATPase SSQ1\tK04043 dnaK; molecular chaperone DnaK"
			}
			]
		},
		{
			"name":"HSP60 \/ Chaperonin",
			"children":[
			{
				"name":"NCAS_0B02870 NCAS0B02870; chaperonin-containing T-complex alpha subunit TCP1\tK09493 CCT1; T-complex protein 1 subunit alpha"
			},
			{
				"name":"NCAS_0B06670 NCAS0B06670; chaperonin-containing T-complex subunit CCT2\tK09494 CCT2; T-complex protein 1 subunit beta"
			},
			{
				"name":"NCAS_0A07070 NCAS0A07070; chaperonin-containing T-complex subunit CCT3\tK09495 CCT3; T-complex protein 1 subunit gamma"
			},
			{
				"name":"NCAS_0A13920 NCAS0A13920; chaperonin-containing T-complex subunit CCT4\tK09496 CCT4; T-complex protein 1 subunit delta"
			},
			{
				"name":"NCAS_0A12260 NCAS0A12260; chaperonin-containing T-complex subunit CCT5\tK09497 CCT5; T-complex protein 1 subunit epsilon"
			},
			{
				"name":"NCAS_0C02890 NCAS0C02890; chaperonin-containing T-complex subunit CCT6\tK09498 CCT6; T-complex protein 1 subunit zeta"
			},
			{
				"name":"NCAS_0B07830 NCAS0B07830; chaperonin-containing T-complex subunit CCT7\tK09499 CCT7; T-complex protein 1 subunit eta"
			},
			{
				"name":"NCAS_0F02060 NCAS0F02060; chaperonin-containing T-complex subunit CCT8\tK09500 CCT8; T-complex protein 1 subunit theta"
			},
			{
				"name":"NCAS_0H00890 NCAS0H00890; chaperone ATPase HSP60\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCAS_0I01750 NCAS0I01750; uncharacterized protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			}
			]
		},
		{
			"name":"HSP47"
		},
		{
			"name":"HSP40 \/ DNAJ",
			"children":[
			{
				"name":"NCAS_0B05030 NCAS0B05030; uncharacterized protein\tK09503 DNAJA2; DnaJ homolog subfamily A member 2"
			},
			{
				"name":"NCAS_0G02850 NCAS0G02850; uncharacterized protein\tK09503 DNAJA2; DnaJ homolog subfamily A member 2"
			},
			{
				"name":"NCAS_0G03000 NCAS0G03000; type I HSP40 co-chaperone YDJ1\tK09503 DNAJA2; DnaJ homolog subfamily A member 2"
			},
			{
				"name":"NCAS_0G01360 NCAS0G01360; uncharacterized protein\tK09506 DNAJA5; DnaJ homolog subfamily A member 5"
			},
			{
				"name":"NCAS_0C04890 NCAS0C04890; uncharacterized protein\tK09510 DNAJB4; DnaJ homolog subfamily B member 4"
			},
			{
				"name":"NCAS_0G03610 NCAS0G03610; type II HSP40 co-chaperone SIS1\tK09510 DNAJB4; DnaJ homolog subfamily B member 4"
			},
			{
				"name":"NCAS_0D00960 NCAS0D00960; type I HSP40 co-chaperone HLJ1\tK09518 DNAJB12; DnaJ homolog subfamily B member 12"
			},
			{
				"name":"NCAS_0E04190 NCAS0E04190; zuotin\tK09522 DNAJC2; DnaJ homolog subfamily C member 2"
			},
			{
				"name":"NCAS_0A09320 NCAS0A09320; uncharacterized protein\tK09523 DNAJC3; DnaJ homolog subfamily C member 3"
			},
			{
				"name":"NCAS_0D02910 NCAS0D02910; uncharacterized protein\tK09539 DNAJC19; DnaJ homolog subfamily C member 19"
			},
			{
				"name":"NCAS_0E01280 NCAS0E01280; uncharacterized protein\tK09539 DNAJC19; DnaJ homolog subfamily C member 19"
			},
			{
				"name":"NCAS_0C01220 NCAS0C01220; protein-transporting protein SEC63\tK09540 SEC63; translocation protein SEC63"
			},
			{
				"name":"NCAS_0C03950 NCAS0C03950; uncharacterized protein\tK03686 dnaJ; molecular chaperone DnaJ"
			},
			{
				"name":"NCAS_0A01690 NCAS0A01690; J-type chaperone JAC1\tK04082 hscB; molecular chaperone HscB"
			}
			]
		},
		{
			"name":"HSP33"
		},
		{
			"name":"HSP24",
			"children":[
			{
				"name":"NCAS_0B01460 NCAS0B01460; uncharacterized protein\tK03687 GRPE; molecular chaperone GrpE"
			}
			]
		},
		{
			"name":"HSP20",
			"children":[
			{
				"name":"NCAS_0A10710 NCAS0A10710; chaperone protein HSP26\tK13993 HSP20; HSP20 family protein"
			},
			{
				"name":"NCAS_0B03220 NCAS0B03220; heat shock protein HSP42\tK13993 HSP20; HSP20 family protein"
			},
			{
				"name":"NCAS_0D01990 NCAS0D01990; uncharacterized protein\tK13993 HSP20; HSP20 family protein"
			}
			]
		},
		{
			"name":"HSP15"
		},
		{
			"name":"HSP10",
			"children":[
			{
				"name":"NCAS_0G00860 NCAS0G00860; uncharacterized protein\tK04078 groES; chaperonin GroES"
			}
			]
		},
		{
			"name":"GimC",
			"children":[
			{
				"name":"NCAS_0I00790 NCAS0I00790; tubulin-binding prefolding complex subunit GIM4\tK09549 PFDN2; prefoldin subunit 2"
			},
			{
				"name":"NCAS_0G02100 NCAS0G02100; tubulin-binding prefolding complex subunit GIM3\tK09550 PFDN4; prefoldin subunit 4"
			},
			{
				"name":"NCAS_0C00170 NCAS0C00170; uncharacterized protein\tK04797 pfdA; prefoldin alpha subunit"
			},
			{
				"name":"NCAS_0E02860 NCAS0E02860; tubulin-binding prefolding complex subunit YKE2\tK04798 pfdB; prefoldin beta subunit"
			}
			]
		}
		]
	},
	{
		"name":"Other chaperones and cochaperones",
		"children":[
		{
			"name":"Calnexin \/ calreticulin"
		},
		{
			"name":"DegP \/ HtrA"
		},
		{
			"name":"AAA proteases",
			"children":[
			{
				"name":"NCAS_0A07820 NCAS0A07820; m-AAA protease subunit YTA12\tK08956 AFG3; AFG3 family protein [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"PapD"
		},
		{
			"name":"SecB"
		},
		{
			"name":"Sti1 \/ p60",
			"children":[
			{
				"name":"NCAS_0A00490 NCAS0A00490; uncharacterized protein\tK09553 STIP1; stress-induced-phosphoprotein 1"
			},
			{
				"name":"NCAS_0G00810 NCAS0G00810; Hsp90 cochaperone STI1\tK09553 STIP1; stress-induced-phosphoprotein 1"
			}
			]
		},
		{
			"name":"Cdc37 \/ p50",
			"children":[
			{
				"name":"NCAS_0B03300 NCAS0B03300; uncharacterized protein\tK09554 CDC37; cell division cycle protein 37"
			}
			]
		},
		{
			"name":"BAG"
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"NCAS_0I01190 NCAS0I01190; Hsp70 nucleotide exchange factor FES1\tK09562 HSPBP1; hsp70-interacting protein"
			},
			{
				"name":"NCAS_0I00550 NCAS0I00550; uncharacterized protein\tK23327 HIKESHI; protein Hikeshi"
			},
			{
				"name":"NCAS_0G03770 NCAS0G03770; uncharacterized protein\tK21804 METTL21A; protein N-lysine methyltransferase METTL21A [EC:2.1.1.-]"
			},
			{
				"name":"NCAS_0G03850 NCAS0G03850; uncharacterized protein\tK21804 METTL21A; protein N-lysine methyltransferase METTL21A [EC:2.1.1.-]"
			},
			{
				"name":"NCAS_0G00750 NCAS0G00750; uncharacterized protein\tK21991 UNC45; protein unc-45"
			},
			{
				"name":"NCAS_0D02670 NCAS0D02670; uncharacterized protein\tK16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha"
			},
			{
				"name":"NCAS_0H00830 NCAS0H00830; uncharacterized protein\tK16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha"
			},
			{
				"name":"NCAS_0B02400 NCAS0B02400; HSP70\/90 family co-chaperone CNS1\tK24927 TTC4; tetratricopeptide repeat protein 4"
			},
			{
				"name":"NCAS_0D04440 NCAS0D04440; uncharacterized protein\tK24962 CCDC47; PAT complex subunit CCDC47"
			},
			{
				"name":"NCAS_0B02850 NCAS0B02850; uncharacterized protein\tK26216 AHSA1; activator of Hsp90 ATPase protein 1"
			},
			{
				"name":"NCAS_0B00590 NCAS0B00590; uncharacterized protein\tK28206 PDCL; phosducin-like protein"
			}
			]
		}
		]
	},
	{
		"name":"Intramolecular chaperones",
		"children":[
		{
			"name":"Subtilisin family",
			"children":[
			{
				"name":"NCAS_0D02630 NCAS0D02630; uncharacterized protein\tK01336 PRB1; cerevisin [EC:3.4.21.48 3.4.21.-]"
			},
			{
				"name":"NCAS_0F00220 NCAS0F00220; proteinase B\tK01336 PRB1; cerevisin [EC:3.4.21.48 3.4.21.-]"
			},
			{
				"name":"NCAS_0D04390 NCAS0D04390; uncharacterized protein\tK14644 OSW3; subtilase-type proteinase RRT12 [EC:3.4.21.-]"
			},
			{
				"name":"NCAS_0A00880 NCAS0A00880; kexin KEX2\tK01341 KEX2; kexin [EC:3.4.21.61]"
			}
			]
		},
		{
			"name":"Papain family"
		},
		{
			"name":"Other peptidases",
			"children":[
			{
				"name":"NCAS_0F02120 NCAS0F02120; carboxypeptidase C PRC1\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
			},
			{
				"name":"NCAS_0I02290 NCAS0I02290; carboxypeptidase C\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
			},
			{
				"name":"NCAS_0B03560 NCAS0B03560; aspartyl protease\tK06009 YPS1_2; yapsin 1\/2 [EC:3.4.23.41]"
			},
			{
				"name":"NCAS_0C03300 NCAS0C03300; uncharacterized protein\tK06009 YPS1_2; yapsin 1\/2 [EC:3.4.23.41]"
			}
			]
		},
		{
			"name":"Others"
		}
		]
	},
	{
		"name":"Protein folding catalysts",
		"children":[
		{
			"name":"Peptidyl prolyl isomerase",
			"children":[
			{
				"name":"Cyclophilin",
				"children":[
				{
					"name":"NCAS_0A06700 NCAS0A06700; peptidylprolyl isomerase CPR2\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"NCAS_0F02710 NCAS0F02710; peptidylprolyl isomerase family protein CPR5\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"NCAS_0A08420 NCAS0A08420; peptidylprolyl isomerase CPR7\tK05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]"
				},
				{
					"name":"NCAS_0E03770 NCAS0E03770; peptidylprolyl isomerase CPR6\tK05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]"
				},
				{
					"name":"NCAS_0C02200 NCAS0C02200; uncharacterized protein\tK12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"FKBP",
				"children":[
				{
					"name":"NCAS_0G02310 NCAS0G02310; peptidylprolyl isomerase FPR1\tK09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]"
				},
				{
					"name":"NCAS_0A00310 NCAS0A00310; peptidylprolyl isomerase family protein FPR2\tK09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"Parvulin",
				"children":[
				{
					"name":"NCAS_0D01720 NCAS0D01720; peptidylprolyl isomerase ESS1\tK09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"
				}
				]
			}
			]
		},
		{
			"name":"Protein disulfide isomerase",
			"children":[
			{
				"name":"NCAS_0A07350 NCAS0A07350; thioredoxin TRX2\tK03671 TXN; thioredoxin"
			},
			{
				"name":"NCAS_0D04790 NCAS0D04790; uncharacterized protein\tK03671 TXN; thioredoxin"
			},
			{
				"name":"NCAS_0A00360 NCAS0A00360; dithiol glutaredoxin GRX2\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"NCAS_0B08870 NCAS0B08870; dithiol glutaredoxin GRX1\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"NCAS_0J01250 NCAS0J01250; glutathione-disulfide reductase GRX8\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"NCAS_0B02290 NCAS0B02290; uncharacterized protein\tK07390 grxD; monothiol glutaredoxin"
			},
			{
				"name":"NCAS_0C02240 NCAS0C02240; monothiol glutaredoxin GRX5\tK07390 grxD; monothiol glutaredoxin"
			},
			{
				"name":"NCAS_0A00320 NCAS0A00320; protein disulfide isomerase EUG1\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
			},
			{
				"name":"NCAS_0B08940 NCAS0B08940; protein disulfide isomerase PDI1\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
			},
			{
				"name":"NCAS_0B00640 NCAS0B00640; protein disulfide isomerase MPD1\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
			},
			{
				"name":"NCAS_0A13140 NCAS0A13140; protein disulfide isomerase EPS1\tK13996 EPS1; protein disulfide-isomerase [EC:5.3.4.1]"
			}
			]
		}
		]
	}
	]
}
