{ "name":"nio00001", "children":[ { "name":"09100 Metabolism", "children":[ { "name":"09101 Carbohydrate metabolism", "children":[ { "name":"00010 Glycolysis \/ Gluconeogenesis [PATH:nio00010]", "children":[ { "name":"NITINOP_0914 glk; Glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"NITINOP_0912 putative Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"NITINOP_0538 pfkA; 6-Phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"NITINOP_3078 fbp; Fructose-1,6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]" }, { "name":"NITINOP_3077 fbaB; Fructose-bisphosphate aldolase class I\tK11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"NITINOP_3159 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"NITINOP_3157 gapA; Glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"NITINOP_3158 pgk; Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"NITINOP_1254 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"NITINOP_0768 apgM; 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase\tK15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]" }, { "name":"NITINOP_2374 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"NITINOP_2630 pykA; Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"NITINOP_2180 ppdK; Pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1653 adhA; putative alcohol dehydrogenase AdhA\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]" }, { "name":"NITINOP_0505 adhC; Alcohol dehydrogenase, NADP-dependent\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]" }, { "name":"NITINOP_2186 acsA; Acetyl-CoA synthetase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"NITINOP_2245 pgm; Phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" } ] }, { "name":"00020 Citrate cycle (TCA cycle) [PATH:nio00020]", "children":[ { "name":"NITINOP_0934 prpC; 2-methylcitrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]" }, { "name":"NITINOP_2323 gltA; Citrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]" }, { "name":"NITINOP_0227 aclA; ATP citrate lyase, alpha subunit\tK15230 aclA; ATP-citrate lyase alpha-subunit [EC:2.3.3.8]" }, { "name":"NITINOP_0228 aclB; ATP-citrate lyase, beta subunit\tK15231 aclB; ATP-citrate lyase beta-subunit [EC:2.3.3.8]" }, { "name":"NITINOP_0226 acnA; Aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"NITINOP_0225 idh; Isocitrate dehydrogenase (NADP(+))\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"NITINOP_1478 Isocitrate dehydrogenase (NAD+)\tK00030 IDH3; isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_0221 sucD; succinyl-CoA synthetase, NAD(P)-binding, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"NITINOP_0222 sucC; succinyl-CoA synthetase, beta subunit\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"NITINOP_1451 sdhA; Succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1452 sdhB; Succinate dehydrogenase\/fumarate reductase, Fe-S protein subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1450 sdhC; Succinate dehydrogenase\/fumarate reductase, cytochrome b558 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"NITINOP_2197 fumC; Fumarate hydratase, class II\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]" }, { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"NITINOP_2206 pycA; Pyruvate carboxylase, subunit A\tK01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]" }, { "name":"NITINOP_2205 pycB; Pyruvate carboxylase, subunit B\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]" }, { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" } ] }, { "name":"00030 Pentose phosphate pathway [PATH:nio00030]", "children":[ { "name":"NITINOP_0912 putative Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"NITINOP_0665 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"NITINOP_2009 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"NITINOP_0913 pgl; 6-phosphogluconolactonase\tK01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]" }, { "name":"NITINOP_2010 yqeC; putative 6-phosphogluconate dehydrogenase YqeC\tK00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]" }, { "name":"NITINOP_1262 rpe; D-ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" }, { "name":"NITINOP_2171 tktA; Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" }, { "name":"NITINOP_1240 tal; putative transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]" }, { "name":"NITINOP_0915 rpiA; Ribose-5-phosphate isomerase A\tK01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]" }, { "name":"NITINOP_0707 putative phosphoketolase 1\tK01621 xfp; xylulose-5-phosphate\/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]" }, { "name":"NITINOP_2532 deoC; Deoxyribose-phosphate aldolase\tK01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]" }, { "name":"NITINOP_2533 deoB; Phosphopentomutase\tK01839 deoB; phosphopentomutase [EC:5.4.2.7]" }, { "name":"NITINOP_2245 pgm; Phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"NITINOP_0276 prsA; phosphoribosylpyrophosphate synthase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"NITINOP_0663 gntK; Thermoresistant gluconokinase\tK00851 idnK; gluconokinase [EC:2.7.1.12]" }, { "name":"NITINOP_1237 ttuD; putative Hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"NITINOP_3077 fbaB; Fructose-bisphosphate aldolase class I\tK11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"NITINOP_3078 fbp; Fructose-1,6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]" }, { "name":"NITINOP_0538 pfkA; 6-Phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" } ] }, { "name":"00040 Pentose and glucuronate interconversions [PATH:nio00040]", "children":[ { "name":"NITINOP_0144 rkpK; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"NITINOP_3139 yngB; putative UTP--glucose-1-phosphate uridylyltransferase YngB\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"NITINOP_1262 rpe; D-ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" } ] }, { "name":"00051 Fructose and mannose metabolism [PATH:nio00051]", "children":[ { "name":"NITINOP_3081 cpsB; mannose-1-phosphate guanyltransferase\tK16011 algA; mannose-1-phosphate guanylyltransferase \/ mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"NITINOP_3384 putative Nucleotidyl transferase\tK00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]" }, { "name":"NITINOP_3114 gmd; GDP-D-mannose dehydratase, NAD(P)-binding\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]" }, { "name":"NITINOP_3113 fcl; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]" }, { "name":"NITINOP_2745 gpgP; Glucosyl-3-phosphoglycerate\/mannosyl-3-phosphoglycerate phosphatase\tK07026 E3.1.3.70; mannosyl-3-phosphoglycerate phosphatase [EC:3.1.3.70]" }, { "name":"NITINOP_0538 pfkA; 6-Phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"NITINOP_3078 fbp; Fructose-1,6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]" }, { "name":"NITINOP_3077 fbaB; Fructose-bisphosphate aldolase class I\tK11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"NITINOP_3159 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" } ] }, { "name":"00052 Galactose metabolism [PATH:nio00052]", "children":[ { "name":"NITINOP_0007 galT; Galactose-1-phosphate uridylyltransferase\tK00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]" }, { "name":"NITINOP_1404 putative UDP-glucose 4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"NITINOP_3180 galE; UDP-galactose-4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"NITINOP_3139 yngB; putative UTP--glucose-1-phosphate uridylyltransferase YngB\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"NITINOP_2245 pgm; Phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"NITINOP_0914 glk; Glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"NITINOP_0538 pfkA; 6-Phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" } ] }, { "name":"00053 Ascorbate and aldarate metabolism [PATH:nio00053]", "children":[ { "name":"NITINOP_0144 rkpK; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"NITINOP_1650 Uncharacterized 37.6 kDa protein in cld 5'region\tK08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]" } ] }, { "name":"00500 Starch and sucrose metabolism [PATH:nio00500]", "children":[ { "name":"NITINOP_3139 yngB; putative UTP--glucose-1-phosphate uridylyltransferase YngB\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"NITINOP_2252 rfbF; Glucose-1-phosphate cytidylyltransferase\tK00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]" }, { "name":"NITINOP_3058 glgC; Glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]" }, { "name":"NITINOP_2381 glgA; Glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]" }, { "name":"NITINOP_0017 glgB; 1,4-alpha-glucan branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]" }, { "name":"NITINOP_1895 1,4-alpha-glucan branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]" }, { "name":"NITINOP_0708 glgP; Alpha-glucan phosphorylase\tK00688 PYG; glycogen phosphorylase [EC:2.4.1.1]" }, { "name":"NITINOP_1709 glgP; Glycogen phosphorylase\tK00688 PYG; glycogen phosphorylase [EC:2.4.1.1]" }, { "name":"NITINOP_2947 glgP; Similar to glycogen phosphorylase\tK00688 PYG; glycogen phosphorylase [EC:2.4.1.1]" }, { "name":"NITINOP_3204 malQ; 4-Alpha-glucanotransferase\tK00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]" }, { "name":"NITINOP_2736 glgX; Glycogen operon protein GlgX homolog\tK01214 ISA; isoamylase [EC:3.2.1.68]" }, { "name":"NITINOP_2734 treY; Similar to maltooligosyl trehalose synthase treY\tK06044 treY; (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase [EC:5.4.99.15]" }, { "name":"NITINOP_2735 Malto-oligosyltrehalose trehalohydrolase\tK01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141]" }, { "name":"NITINOP_2747 otsA; Alpha,alpha-trehalose-phosphate synthase (UDP-forming)\tK00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347]" }, { "name":"NITINOP_2746 putative Trehalose phosphatase\tK01087 otsB; trehalose 6-phosphate phosphatase [EC:3.1.3.12]" }, { "name":"NITINOP_2245 pgm; Phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"NITINOP_0914 glk; Glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"NITINOP_0912 putative Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" } ] }, { "name":"00620 Pyruvate metabolism [PATH:nio00620]", "children":[ { "name":"NITINOP_2186 acsA; Acetyl-CoA synthetase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_1653 adhA; putative alcohol dehydrogenase AdhA\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]" }, { "name":"NITINOP_0505 adhC; Alcohol dehydrogenase, NADP-dependent\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]" }, { "name":"NITINOP_0681 ackA; Acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]" }, { "name":"NITINOP_2630 pykA; Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"NITINOP_2679 accA; acetyl-CoA carboxylase, carboxytransferase, alpha subunit\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_2778 accB; Acetyl CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"NITINOP_2777 accC; acetyl-CoA carboxylase, biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"NITINOP_2820 accD; acetyl-CoA carboxylase, beta (carboxyltranferase) subunit\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_3218 acyP; Acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]" }, { "name":"NITINOP_1363 putative lactoylglutathione lyase\tK01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]" }, { "name":"NITINOP_1498 putative Hydrolase with N-terminal DNA-binding domain\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]" }, { "name":"NITINOP_3372 putative enzyme\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]" }, { "name":"NITINOP_2316 maeB; Malate dehydrogenase (oxaloacetate-decarboxylating)\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]" }, { "name":"NITINOP_2206 pycA; Pyruvate carboxylase, subunit A\tK01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]" }, { "name":"NITINOP_2205 pycB; Pyruvate carboxylase, subunit B\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]" }, { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"NITINOP_2197 fumC; Fumarate hydratase, class II\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]" }, { "name":"NITINOP_2180 ppdK; Pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0100 leuA; 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]" }, { "name":"NITINOP_1137 Uncharacterized AIPM\/Hcit synthase family transferase TM_0552\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]" } ] }, { "name":"00630 Glyoxylate and dicarboxylate metabolism [PATH:nio00630]", "children":[ { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"NITINOP_0934 prpC; 2-methylcitrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]" }, { "name":"NITINOP_2323 gltA; Citrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]" }, { "name":"NITINOP_0226 acnA; Aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"NITINOP_2186 acsA; Acetyl-CoA synthetase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_1434 katA; catalase (hydroperoxidase II)\tK03781 katE; catalase [EC:1.11.1.6]" }, { "name":"NITINOP_2572 tiaE; 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase)\tK00015 gyaR; glyoxylate reductase [EC:1.1.1.26]" }, { "name":"NITINOP_1495 putative Phosphoglycolate phosphatase\tK01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]" }, { "name":"NITINOP_3380 gltB; glutamate synthase, large subunit\tK00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]" }, { "name":"NITINOP_1778 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"NITINOP_1661 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"NITINOP_1005 gcvP; glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"NITINOP_0849 gcvT; Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_2492 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" }, { "name":"NITINOP_1237 ttuD; putative Hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"NITINOP_0666 Cyclase family protein\tK07130 kynB; arylformamidase [EC:3.5.1.9]" }, { "name":"NITINOP_1058 purU; Formyltetrahydrofolate deformylase\tK01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]" } ] }, { "name":"00640 Propanoate metabolism [PATH:nio00640]", "children":[ { "name":"NITINOP_2186 acsA; Acetyl-CoA synthetase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"NITINOP_0681 ackA; Acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_2679 accA; acetyl-CoA carboxylase, carboxytransferase, alpha subunit\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_2778 accB; Acetyl CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"NITINOP_2777 accC; acetyl-CoA carboxylase, biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"NITINOP_2820 accD; acetyl-CoA carboxylase, beta (carboxyltranferase) subunit\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_0222 sucC; succinyl-CoA synthetase, beta subunit\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"NITINOP_0221 sucD; succinyl-CoA synthetase, NAD(P)-binding, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"NITINOP_0934 prpC; 2-methylcitrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]" }, { "name":"NITINOP_2323 gltA; Citrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]" }, { "name":"NITINOP_0936 prpD; 2-methylcitrate dehydratase\tK01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79]" }, { "name":"NITINOP_0226 acnA; Aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"NITINOP_0935 prpB; 2-methylisocitrate lyase\tK03417 prpB; methylisocitrate lyase [EC:4.1.3.30]" } ] }, { "name":"00650 Butanoate metabolism [PATH:nio00650]", "children":[ { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0945 mmgB; putative 3-hydroxybutyryl-CoA dehydrogenase\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]" }, { "name":"NITINOP_1451 sdhA; Succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1452 sdhB; Succinate dehydrogenase\/fumarate reductase, Fe-S protein subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1450 sdhC; Succinate dehydrogenase\/fumarate reductase, cytochrome b558 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0939 mvaB; Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"NITINOP_0105 ilvI; acetolactate synthase III, large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"NITINOP_0104 ilvH; acetolactate synthase III, thiamin-dependent, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" } ] }, { "name":"00660 C5-Branched dibasic acid metabolism [PATH:nio00660]", "children":[ { "name":"NITINOP_0105 ilvI; acetolactate synthase III, large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"NITINOP_0104 ilvH; acetolactate synthase III, thiamin-dependent, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" }, { "name":"NITINOP_0222 sucC; succinyl-CoA synthetase, beta subunit\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"NITINOP_0221 sucD; succinyl-CoA synthetase, NAD(P)-binding, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"NITINOP_0800 leuC; 3-isopropylmalate dehydratase (isomerase), subunit with LeuD\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"NITINOP_0801 leuD; 3-isopropylmalate isomerase subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"NITINOP_0098 leuB; 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]" } ] }, { "name":"00562 Inositol phosphate metabolism [PATH:nio00562]", "children":[ { "name":"NITINOP_1445 suhB; Inositol-1-monophosphatase\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]" }, { "name":"NITINOP_0313 putative sugar nucleotidyltransferase and phosphatidyltransferase (Bifunctional enzyme)\tK23992 K23992; 1L-myo-inositol 1-phosphate cytidylyltransferase \/ CDP-L-myo-inositol myo-inositolphosphotransferase [EC:2.7.7.74 2.7.8.34]" }, { "name":"NITINOP_3159 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" } ] }, { "name":"00566 Sulfoquinovose metabolism", "children":[ { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" } ] } ] }, { "name":"09102 Energy metabolism", "children":[ { "name":"00190 Oxidative phosphorylation [PATH:nio00190]", "children":[ { "name":"NITINOP_1107 nuoA; NADH-quinone oxidoreductase subunit A\tK00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]" }, { "name":"NITINOP_1379 nuoA; NADH-quinone oxidoreductase subunit A\tK00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]" }, { "name":"NITINOP_1108 nuoB; NADH-quinone oxidoreductase subunit B 2\tK00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]" }, { "name":"NITINOP_1378 nuoB; NADH-quinone oxidoreductase subunit B 1\tK00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]" }, { "name":"NITINOP_1109 nuoC; NADH-quinone oxidoreductase subunit C\tK00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]" }, { "name":"NITINOP_1110 nuoD; NADH-quinone oxidoreductase subunit D\tK00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]" }, { "name":"NITINOP_1377 nuoC; NADH-quinone oxidoreductase subunit C\/D 2\tK13378 nuoCD; NADH-quinone oxidoreductase subunit C\/D [EC:7.1.1.2]" }, { "name":"NITINOP_1376 nuoE; NADH-quinone oxidoreductase subunit E 2\tK00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]" }, { "name":"NITINOP_0978 nuoF; NADH-quinone oxidoreductase subunit F 2\tK00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]" }, { "name":"NITINOP_1375 nuoF; NADH:ubiquinone oxidoreductase, chain F\tK00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]" }, { "name":"NITINOP_1373 nuoH; NADH-quinone oxidoreductase subunit H 2\tK00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]" }, { "name":"NITINOP_1112 nuoI; NADH-quinone oxidoreductase subunit I\tK00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]" }, { "name":"NITINOP_1372 nuoI; NADH-quinone oxidoreductase subunit I\tK00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]" }, { "name":"NITINOP_1113 nuoJ; NADH-quinone oxidoreductase, membrane subunit J\tK00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]" }, { "name":"NITINOP_1371 nuoJ; NADH-quinone oxidoreductase subunit J\tK00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]" }, { "name":"NITINOP_1114 nuoK; NADH-quinone oxidoreductase subunit K\tK00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]" }, { "name":"NITINOP_1370 nuoK; NADH-quinone oxidoreductase subunit K\tK00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]" }, { "name":"NITINOP_1115 nuoL; NADH:ubiquinone oxidoreductase, membrane subunit L\tK00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]" }, { "name":"NITINOP_1369 nuoL; NADH-quinone oxidoreductase subunit L\tK00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]" }, { "name":"NITINOP_1116 nuoM; NADH-quinone oxidoreductase, membrane subunit M\tK00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]" }, { "name":"NITINOP_1117 nuoM; NADH-quinone oxidoreductase, membrane subunit M\tK00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]" }, { "name":"NITINOP_1368 nuoM; NADH-quinone oxidoreductase subunit M\tK00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]" }, { "name":"NITINOP_1118 nuoN; NADH-quinone oxidoreductase subunit N\tK00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]" }, { "name":"NITINOP_1367 nuoN; NADH-quinone oxidoreductase subunit N 2\tK00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]" }, { "name":"NITINOP_2111 ndh; NADH dehydrogenase\tK03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]" }, { "name":"NITINOP_1451 sdhA; Succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1452 sdhB; Succinate dehydrogenase\/fumarate reductase, Fe-S protein subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1450 sdhC; Succinate dehydrogenase\/fumarate reductase, cytochrome b558 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"NITINOP_1592 putative Quinol-cytochrome c reductase, cytochrome b subunit\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit" }, { "name":"NITINOP_0461 conserved exported protein of unknown function\tK02297 cyoA; cytochrome o ubiquinol oxidase subunit II [EC:7.1.1.3]" }, { "name":"NITINOP_0673 cydA; Cytochrome bd oxidase, subunit I\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_1589 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_1594 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_3338 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_3345 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_0672 cydB; Cytochrome bd oxidase, subunit II\tK00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]" }, { "name":"NITINOP_0687 atpA; F1 sector of membrane-bound ATP synthase, alpha subunit\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_1179 atpA; F1 sector of membrane-bound ATP synthase, alpha subunit\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_0693 atpD; F1 sector of membrane-bound ATP synthase, beta subunit\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_1181 atpD; membrane-bound ATP synthase, F1 sector, beta-subunit\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_0682 ATP synthase gamma subunit C-terminus\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"NITINOP_1180 atpG; ATP synthase gamma chain\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"NITINOP_1178 atpH; ATP synthase subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta" }, { "name":"NITINOP_0692 H+transporting two-sector ATPase delta\/epsilon subunit\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"NITINOP_1182 atpC; ATP synthase epsilon chain\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"NITINOP_0690 atpB; ATP synthase subunit a 2\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"NITINOP_1388 atpB; ATP synthase subunit a\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"NITINOP_0688 atpF; ATP synthase subunit b\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"NITINOP_1390 atpF; ATP synthase subunit b\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"NITINOP_0689 atpE; ATP synthase subunit c 2\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"NITINOP_1389 atpE; ATP synthase subunit c\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"NITINOP_0636 putative Polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" } ] }, { "name":"00195 Photosynthesis" }, { "name":"00196 Photosynthesis - antenna proteins" }, { "name":"00710 Carbon fixation by Calvin cycle [PATH:nio00710]", "children":[ { "name":"NITINOP_3158 pgk; Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"NITINOP_3157 gapA; Glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"NITINOP_3077 fbaB; Fructose-bisphosphate aldolase class I\tK11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"NITINOP_3078 fbp; Fructose-1,6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]" }, { "name":"NITINOP_2171 tktA; Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" }, { "name":"NITINOP_0915 rpiA; Ribose-5-phosphate isomerase A\tK01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]" }, { "name":"NITINOP_3159 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"NITINOP_1262 rpe; D-ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" }, { "name":"NITINOP_1240 tal; putative transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]" }, { "name":"NITINOP_2180 ppdK; Pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" } ] }, { "name":"00720 Other carbon fixation pathways [PATH:nio00720]", "children":[ { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_2180 ppdK; Pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"NITINOP_2206 pycA; Pyruvate carboxylase, subunit A\tK01959 pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]" }, { "name":"NITINOP_2205 pycB; Pyruvate carboxylase, subunit B\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]" }, { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"NITINOP_2197 fumC; Fumarate hydratase, class II\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]" }, { "name":"NITINOP_1451 sdhA; Succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1452 sdhB; Succinate dehydrogenase\/fumarate reductase, Fe-S protein subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"NITINOP_1450 sdhC; Succinate dehydrogenase\/fumarate reductase, cytochrome b558 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"NITINOP_0221 sucD; succinyl-CoA synthetase, NAD(P)-binding, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"NITINOP_0222 sucC; succinyl-CoA synthetase, beta subunit\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0225 idh; Isocitrate dehydrogenase (NADP(+))\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"NITINOP_0226 acnA; Aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"NITINOP_0227 aclA; ATP citrate lyase, alpha subunit\tK15230 aclA; ATP-citrate lyase alpha-subunit [EC:2.3.3.8]" }, { "name":"NITINOP_0228 aclB; ATP-citrate lyase, beta subunit\tK15231 aclB; ATP-citrate lyase beta-subunit [EC:2.3.3.8]" }, { "name":"NITINOP_2679 accA; acetyl-CoA carboxylase, carboxytransferase, alpha subunit\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_2778 accB; Acetyl CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"NITINOP_2777 accC; acetyl-CoA carboxylase, biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"NITINOP_2820 accD; acetyl-CoA carboxylase, beta (carboxyltranferase) subunit\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_1513 fhs; Formate--tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]" }, { "name":"NITINOP_0249 folD; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase and 5,10-methylene-tetrahydrofolate cyclohydrolase\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]" }, { "name":"NITINOP_0248 metF; Methylenetetrahydrofolate reductase\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]" }, { "name":"NITINOP_0681 ackA; Acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]" }, { "name":"NITINOP_2186 acsA; Acetyl-CoA synthetase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" } ] }, { "name":"00680 Methane metabolism [PATH:nio00680]", "children":[ { "name":"NITINOP_1854 amoB; Ammonia monooxygenase, subunit B\tK10945 pmoB-amoB; methane\/ammonia monooxygenase subunit B" }, { "name":"NITINOP_0766 amoC3; Ammonia monooxygenase, subunit C\tK10946 pmoC-amoC; methane\/ammonia monooxygenase subunit C" }, { "name":"NITINOP_1259 amoC2; Ammonia monooxygenase, subunit C\tK10946 pmoC-amoC; methane\/ammonia monooxygenase subunit C" }, { "name":"NITINOP_1852 amoC1; Ammonia monooxygenase, subunit C\tK10946 pmoC-amoC; methane\/ammonia monooxygenase subunit C" }, { "name":"NITINOP_1661 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"NITINOP_1237 ttuD; putative Hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"NITINOP_2374 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"NITINOP_3077 fbaB; Fructose-bisphosphate aldolase class I\tK11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"NITINOP_3078 fbp; Fructose-1,6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]" }, { "name":"NITINOP_0538 pfkA; 6-Phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"NITINOP_0681 ackA; Acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]" }, { "name":"NITINOP_2186 acsA; Acetyl-CoA synthetase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1254 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"NITINOP_0768 apgM; 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase\tK15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]" }, { "name":"NITINOP_2643 serA; D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"NITINOP_0893 thrH; Homoserine kinase\tK02203 thrH; phosphoserine \/ homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39]" }, { "name":"NITINOP_0317 comD; Sulfopyruvate decarboxylase, alpha subunit\tK06034 comD; sulfopyruvate decarboxylase subunit alpha [EC:4.1.1.79]" }, { "name":"NITINOP_0316 comE; Sulfopyruvate decarboxylase subunit beta\tK13039 comE; sulfopyruvate decarboxylase subunit beta [EC:4.1.1.79]" } ] }, { "name":"00910 Nitrogen metabolism [PATH:nio00910]", "children":[ { "name":"NITINOP_0879 nxrA; Nitrite oxidoreductase, alpha subunit\tK00370 narG; nitrate reductase \/ nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]" }, { "name":"NITINOP_0878 nxrB; Nitrate oxidoreductase, beta subunit\tK00371 narH; nitrate reductase \/ nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]" }, { "name":"NITINOP_2904 napA; Periplasmic nitrate reductase\tK02567 napA; nitrate reductase (cytochrome) [EC:1.9.6.1]" }, { "name":"NITINOP_0678 nrfA; Pentaheme cytochrome c nitrite reductase NrfA\tK03385 nrfA; nitrite reductase (cytochrome c-552) [EC:1.7.2.2]" }, { "name":"NITINOP_0679 nrfH; Tetraheme cytochrome c NrfH\tK15876 nrfH; cytochrome c nitrite reductase small subunit" }, { "name":"NITINOP_1967 putative Cytochrome c-type protein\tK15876 nrfH; cytochrome c nitrite reductase small subunit" }, { "name":"NITINOP_3146 nirK; Copper-containing nitrite reductase (NO-forming)\tK00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]" }, { "name":"NITINOP_1853 amoA; Ammonia monooxygenase, subunit A\tK28504 amoA; ammonia monooxygenase subunit A [EC:1.14.99.39]" }, { "name":"NITINOP_1854 amoB; Ammonia monooxygenase, subunit B\tK10945 pmoB-amoB; methane\/ammonia monooxygenase subunit B" }, { "name":"NITINOP_0766 amoC3; Ammonia monooxygenase, subunit C\tK10946 pmoC-amoC; methane\/ammonia monooxygenase subunit C" }, { "name":"NITINOP_1259 amoC2; Ammonia monooxygenase, subunit C\tK10946 pmoC-amoC; methane\/ammonia monooxygenase subunit C" }, { "name":"NITINOP_1852 amoC1; Ammonia monooxygenase, subunit C\tK10946 pmoC-amoC; methane\/ammonia monooxygenase subunit C" }, { "name":"NITINOP_0065 hao; Hydroxylamine dehydrogenase\tK10535 hao; hydroxylamine dehydrogenase [EC:1.7.2.6]" }, { "name":"NITINOP_1303 gdhA; Glutamate dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]" }, { "name":"NITINOP_1778 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"NITINOP_3379 gltD; Glutamate synthase [NADPH] small chain\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]" }, { "name":"NITINOP_3380 gltB; glutamate synthase, large subunit\tK00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]" }, { "name":"NITINOP_0852 putative Sulfate transporter\tK01673 cynT; carbonic anhydrase [EC:4.2.1.1]" }, { "name":"NITINOP_0841 cah; Carbonic anhydrase (Carbonate dehydratase)\tK01674 cah; carbonic anhydrase [EC:4.2.1.1]" }, { "name":"NITINOP_1064 yrdA; Protein YrdA\tK28956 E4.2.1.1; carbonic anhydrase [EC:4.2.1.1]" } ] }, { "name":"00920 Sulfur metabolism [PATH:nio00920]", "children":[ { "name":"NITINOP_1277 cysNC; Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme)\tK00955 cysNC; bifunctional enzyme CysN\/CysC [EC:2.7.7.4 2.7.1.25]" }, { "name":"NITINOP_0857 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_1276 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_0553 cysC; putative adenylyl-sulfate kinase\tK00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]" }, { "name":"NITINOP_3115 cysC; adenosine 5'-phosphosulfate kinase\tK00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]" }, { "name":"NITINOP_1274 cysH; Phosphoadenosine phosphosulfate reductase\tK00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]" }, { "name":"NITINOP_1273 putative Sulfite reductase, contains SirA-like domain\tK00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]" }, { "name":"NITINOP_0717 sqr; Sulfide:quinone oxidoreductase\tK17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]" }, { "name":"NITINOP_0640 putative Quinol-cytochrome c reductase, cytochrome c subunit\tK19713 tsdA; thiosulfate dehydrogenase [EC:1.8.2.2]" }, { "name":"NITINOP_3274 putative 3-mercaptopyruvate sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]" }, { "name":"NITINOP_3073 cysE; Serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]" }, { "name":"NITINOP_3041 cysK; cysteine synthase A, O-acetylserine sulfhydrolase A subunit\tK01738 cysK; cysteine synthase [EC:2.5.1.47]" } ] } ] }, { "name":"09103 Lipid metabolism", "children":[ { "name":"00061 Fatty acid biosynthesis [PATH:nio00061]", "children":[ { "name":"NITINOP_2679 accA; acetyl-CoA carboxylase, carboxytransferase, alpha subunit\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_2778 accB; Acetyl CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"NITINOP_2777 accC; acetyl-CoA carboxylase, biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"NITINOP_2820 accD; acetyl-CoA carboxylase, beta (carboxyltranferase) subunit\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]" }, { "name":"NITINOP_0210 Acyl carrier protein\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_0257 acpP; acyl carrier protein (ACP)\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_2565 Acyl carrier protein (modular protein)\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_0259 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"NITINOP_0260 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"NITINOP_1563 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase 3\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"NITINOP_0204 Beta-ketoacyl synthase\tK00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]" }, { "name":"NITINOP_0256 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"NITINOP_2566 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"NITINOP_0161 Uncharacterized oxidoreductase MexAM1_META1p0182\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0192 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0201 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0258 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2238 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2516 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0208 protein of unknown function\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"NITINOP_3134 fabZ; (3R)-hydroxymyristol acyl carrier protein dehydratase\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"NITINOP_0846 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]" }, { "name":"NITINOP_0743 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0933 putative 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" } ] }, { "name":"00062 Fatty acid elongation" }, { "name":"00071 Fatty acid degradation [PATH:nio00071]", "children":[ { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0937 paaF; enoyl-CoA hydratase-isomerase\tK13767 fadB; enoyl-CoA hydratase [EC:4.2.1.17]" }, { "name":"NITINOP_0743 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0933 putative 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_1933 Putative fused MFS-type Permease and bifunctional Acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase\/Acyl-[acyl-carrier-protein] synthetase (fragment)\tK05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase \/ long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]" }, { "name":"NITINOP_1653 adhA; putative alcohol dehydrogenase AdhA\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]" } ] }, { "name":"00073 Cutin, suberine and wax biosynthesis" }, { "name":"00074 Mycolic acid biosynthesis", "children":[ { "name":"NITINOP_0210 Acyl carrier protein\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_0257 acpP; acyl carrier protein (ACP)\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_2565 Acyl carrier protein (modular protein)\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_0259 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" } ] }, { "name":"00100 Steroid biosynthesis [PATH:nio00100]", "children":[ { "name":"NITINOP_3226 Farnesyl-diphosphate farnesyltransferase\tK00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]" } ] }, { "name":"00120 Primary bile acid biosynthesis" }, { "name":"00121 Secondary bile acid biosynthesis" }, { "name":"00140 Steroid hormone biosynthesis" }, { "name":"00561 Glycerolipid metabolism [PATH:nio00561]", "children":[ { "name":"NITINOP_1237 ttuD; putative Hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"NITINOP_0505 adhC; Alcohol dehydrogenase, NADP-dependent\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]" }, { "name":"NITINOP_0261 plsX; Phosphate acyltransferase\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]" }, { "name":"NITINOP_2864 plsY; Glycerol-3-phosphate acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"NITINOP_1291 putative Acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"NITINOP_1670 putative Phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"NITINOP_1689 Glycosyltransferase\tK27597 K27597; 1,2-diacylglycerol 3-alpha-glucosyltransferase\/glucuronosyltransferase [EC:2.4.1.337 2.4.1.-]" } ] }, { "name":"00564 Glycerophospholipid metabolism [PATH:nio00564]", "children":[ { "name":"NITINOP_1203 gpsA; Glycerol-3-phosphate dehydrogenase [NAD(P)+]\tK00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]" }, { "name":"NITINOP_0533 putative Fe-S oxidoreductase\tK00113 glpC; glycerol-3-phosphate dehydrogenase subunit C" }, { "name":"NITINOP_2864 plsY; Glycerol-3-phosphate acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"NITINOP_1291 putative Acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"NITINOP_1670 putative Phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"NITINOP_2359 Glycerophosphoryl diester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]" }, { "name":"NITINOP_1933 Putative fused MFS-type Permease and bifunctional Acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase\/Acyl-[acyl-carrier-protein] synthetase (fragment)\tK05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase \/ long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]" }, { "name":"NITINOP_1227 pmtA; Phosphatidylethanolamine N-methyltransferase\tK00570 pmtA; phosphatidylethanolamine\/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]" }, { "name":"NITINOP_1983 cdsA; Phosphatidate cytidylyltransferase\tK00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]" }, { "name":"NITINOP_0101 pssA; CDP-diacylglycerol-serine O-phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]" }, { "name":"NITINOP_0102 psd; Phosphatidylserine decarboxylase proenzyme\tK01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]" }, { "name":"NITINOP_2866 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase\tK00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]" }, { "name":"NITINOP_0282 pgsA; CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase\tK08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]" } ] }, { "name":"00565 Ether lipid metabolism" }, { "name":"00600 Sphingolipid metabolism" }, { "name":"00590 Arachidonic acid metabolism" }, { "name":"00591 Linoleic acid metabolism" }, { "name":"00592 alpha-Linolenic acid metabolism" }, { "name":"01040 Biosynthesis of unsaturated fatty acids [PATH:nio01040]", "children":[ { "name":"NITINOP_2216 desC; Fatty acid desaturase, type 1\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]" }, { "name":"NITINOP_3351 scdA; Stearoyl-CoA 9-desaturase\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]" }, { "name":"NITINOP_0887 Esterase TesA (modular protein)\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]" }, { "name":"NITINOP_2004 conserved protein of unknown function\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]" } ] } ] }, { "name":"09104 Nucleotide metabolism", "children":[ { "name":"00230 Purine metabolism [PATH:nio00230]", "children":[ { "name":"NITINOP_0848 nudF; ADP-ribose pyrophosphatase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]" }, { "name":"NITINOP_2533 deoB; Phosphopentomutase\tK01839 deoB; phosphopentomutase [EC:5.4.2.7]" }, { "name":"NITINOP_2245 pgm; Phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"NITINOP_0276 prsA; phosphoribosylpyrophosphate synthase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"NITINOP_1804 purF; Amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" }, { "name":"NITINOP_2672 purD; phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase\tK01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]" }, { "name":"NITINOP_2233 purN; phosphoribosylglycinamide formyltransferase 1\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]" }, { "name":"NITINOP_1803 purL; Phosphoribosylformylglycinamidine synthase 2\tK23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]" }, { "name":"NITINOP_1800 conserved protein of unknown function\tK23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]" }, { "name":"NITINOP_1801 purQ; Phosphoribosylformylglycinamidine synthase 1\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"NITINOP_2232 purM; phosphoribosylaminoimidazole synthetase\tK01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]" }, { "name":"NITINOP_0486 purK; Phosphoribosylaminoimidazole carboxylase, ATPase subunit\tK01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]" }, { "name":"NITINOP_0487 purE; N5-carboxyaminoimidazole ribonucleotide mutase\tK01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]" }, { "name":"NITINOP_1798 purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase\tK01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]" }, { "name":"NITINOP_1796 purB; Adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]" }, { "name":"NITINOP_2673 purH; fused IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"NITINOP_3216 apt; adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]" }, { "name":"NITINOP_3196 ushA; 5'-nucleotidase\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]" }, { "name":"NITINOP_1140 surE; 5'-nucleotidase SurE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]" }, { "name":"NITINOP_1411 putative HAD-like hydrolase, purine nucleotidase\tK20881 yrfG; GMP\/IMP 5'-nucleotidase [EC:3.1.3.-]" }, { "name":"NITINOP_0289 conserved protein of unknown function\tK05810 LACC1; purine-nucleoside\/S-methyl-5'-thioadenosine phosphorylase \/ adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]" }, { "name":"NITINOP_2484 hpt; Hypoxanthine-guanine phosphoribosyltransferase\tK00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]" }, { "name":"NITINOP_1827 guaB; IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]" }, { "name":"NITINOP_2491 ndk; multifunctional nucleoside diphosphate kinase and apyrimidinic endonuclease and 3'-phosphodiesterase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"NITINOP_3010 Non-canonical purine NTP pyrophosphatase\tK01519 rdgB; XTP\/dITP diphosphohydrolase [EC:3.6.1.66]" }, { "name":"NITINOP_1828 guaA; GMP synthetase (glutamine aminotransferase)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]" }, { "name":"NITINOP_2784 gmk; Guanylate kinase\tK00942 gmk; guanylate kinase [EC:2.7.4.8]" }, { "name":"NITINOP_0347 Ribonucleoside-diphosphate reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_1994 nrdZ; Ribonucleoside-diphosphate reductase NrdZ\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_2043 nrdJ; Vitamin B12-dependent ribonucleotide reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_0346 Ribonucleoside-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]" }, { "name":"NITINOP_3287 relA; GTP pyrophosphokinase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]" }, { "name":"NITINOP_1816 putative Exopolyphosphatase\tK01524 ppx-gppA; exopolyphosphatase \/ guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]" }, { "name":"NITINOP_2313 putative Exopolyphosphatase\tK01524 ppx-gppA; exopolyphosphatase \/ guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]" }, { "name":"NITINOP_0969 purA; adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]" }, { "name":"NITINOP_1400 conserved protein of unknown function\tK09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]" }, { "name":"NITINOP_1752 adk; Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]" }, { "name":"NITINOP_2226 mazG; Nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"NITINOP_0246 apaH; Bis(5'-nucleosyl)-tetraphosphatase, symmetrical\tK01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41]" }, { "name":"NITINOP_1277 cysNC; Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme)\tK00955 cysNC; bifunctional enzyme CysN\/CysC [EC:2.7.7.4 2.7.1.25]" }, { "name":"NITINOP_0553 cysC; putative adenylyl-sulfate kinase\tK00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]" }, { "name":"NITINOP_3115 cysC; adenosine 5'-phosphosulfate kinase\tK00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]" }, { "name":"NITINOP_0857 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_1276 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_3355 ureC; Urease, alpha subunit\tK01428 ureC; urease subunit alpha [EC:3.5.1.5]" }, { "name":"NITINOP_3357 ureA; Urease gamma subunit\tK01430 ureA; urease subunit gamma [EC:3.5.1.5]" }, { "name":"NITINOP_3356 ureB; Urease, beta subunit (modular protein)\tK14048 ureAB; urease subunit gamma\/beta [EC:3.5.1.5]" } ] }, { "name":"00240 Pyrimidine metabolism [PATH:nio00240]", "children":[ { "name":"NITINOP_2878 carB; carbamoyl-phosphate synthase, large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"NITINOP_2881 carA; carbamoyl phosphate synthetase small subunit, glutamine amidotransferase\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]" }, { "name":"NITINOP_2884 pyrB; Aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]" }, { "name":"NITINOP_2883 pyrC; Dihydroorotase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]" }, { "name":"NITINOP_2763 pyrD; putative dihydroorotate dehydrogenase A (fumarate)\tK00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]" }, { "name":"NITINOP_0950 putative Orotate phosphoribosyltransferase (Modular protein)\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]" }, { "name":"NITINOP_1125 pyrE; Orotate phosphoribosyltransferase\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]" }, { "name":"NITINOP_1417 pyrF; Orotidine 5'-phosphate decarboxylase\tK01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]" }, { "name":"NITINOP_2461 pyrH; uridylate kinase\tK09903 pyrH; uridylate kinase [EC:2.7.4.22]" }, { "name":"NITINOP_2491 ndk; multifunctional nucleoside diphosphate kinase and apyrimidinic endonuclease and 3'-phosphodiesterase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"NITINOP_2226 mazG; Nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"NITINOP_0479 Maf-like protein Adeh_2502\tK06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]" }, { "name":"NITINOP_2869 pyrG; CTP synthetase\tK01937 pyrG; CTP synthase [EC:6.3.4.2]" }, { "name":"NITINOP_1290 cmk; cytidylate kinase\tK00945 cmk; CMP\/dCMP kinase [EC:2.7.4.25]" }, { "name":"NITINOP_3196 ushA; 5'-nucleotidase\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]" }, { "name":"NITINOP_1140 surE; 5'-nucleotidase SurE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]" }, { "name":"NITINOP_2885 pyrR; Bifunctional protein PyrR [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase]\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]" }, { "name":"NITINOP_1400 conserved protein of unknown function\tK09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]" }, { "name":"NITINOP_0188 dcd; 2'-deoxycytidine 5'-triphosphate deaminase\tK01494 dcd; dCTP deaminase [EC:3.5.4.13]" }, { "name":"NITINOP_0347 Ribonucleoside-diphosphate reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_1994 nrdZ; Ribonucleoside-diphosphate reductase NrdZ\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_2043 nrdJ; Vitamin B12-dependent ribonucleotide reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_0346 Ribonucleoside-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]" }, { "name":"NITINOP_2311 tmk; Thymidylate kinase\tK00943 tmk; dTMP kinase [EC:2.7.4.9]" }, { "name":"NITINOP_2312 tmk; putative thymidylate kinase\tK00943 tmk; dTMP kinase [EC:2.7.4.9]" }, { "name":"NITINOP_2364 tmk; Thymidylate kinase\tK00943 tmk; dTMP kinase [EC:2.7.4.9]" } ] } ] }, { "name":"09105 Amino acid metabolism", "children":[ { "name":"00250 Alanine, aspartate and glutamate metabolism [PATH:nio00250]", "children":[ { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_1383 nadB; L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]" }, { "name":"NITINOP_1464 iaaA; Isoaspartyl peptidase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]" }, { "name":"NITINOP_0434 Asparagine synthetase\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"NITINOP_2394 Asparagine synthetase\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"NITINOP_2425 Asparagine synthetase\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"NITINOP_3220 ald; Alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]" }, { "name":"NITINOP_1250 argG; Argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]" }, { "name":"NITINOP_1249 argH; Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]" }, { "name":"NITINOP_0969 purA; adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]" }, { "name":"NITINOP_1796 purB; Adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]" }, { "name":"NITINOP_2884 pyrB; Aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]" }, { "name":"NITINOP_3379 gltD; Glutamate synthase [NADPH] small chain\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]" }, { "name":"NITINOP_1303 gdhA; Glutamate dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]" }, { "name":"NITINOP_2240 putA; Bifunctional protein PutA\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]" }, { "name":"NITINOP_1778 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"NITINOP_2878 carB; carbamoyl-phosphate synthase, large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"NITINOP_2881 carA; carbamoyl phosphate synthetase small subunit, glutamine amidotransferase\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]" }, { "name":"NITINOP_1801 purQ; Phosphoribosylformylglycinamidine synthase 1\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"NITINOP_2367 glmS; L-glutamine:D-fructose-6-phosphate aminotransferase\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"NITINOP_1804 purF; Amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" } ] }, { "name":"00260 Glycine, serine and threonine metabolism [PATH:nio00260]", "children":[ { "name":"NITINOP_0767 lysC; Aspartokinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"NITINOP_0096 asd; Aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"NITINOP_0770 hom; Homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]" }, { "name":"NITINOP_0893 thrH; Homoserine kinase\tK02203 thrH; phosphoserine \/ homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39]" }, { "name":"NITINOP_0769 thrC; Threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" }, { "name":"NITINOP_3043 thrC; Threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" }, { "name":"NITINOP_2012 ltaA; L-allo-threonine aldolase\tK01620 ltaE; threonine aldolase [EC:4.1.2.48]" }, { "name":"NITINOP_1661 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"NITINOP_1237 ttuD; putative Hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"NITINOP_1254 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"NITINOP_0768 apgM; 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase\tK15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]" }, { "name":"NITINOP_2643 serA; D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"NITINOP_1659 kbl; glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]" }, { "name":"NITINOP_1657 tdh; threonine 3-dehydrogenase, NAD(P)-binding\tK00060 tdh; threonine 3-dehydrogenase [EC:1.1.1.103]" }, { "name":"NITINOP_0832 Amine oxidase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"NITINOP_1005 gcvP; glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"NITINOP_0849 gcvT; Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_2492 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" }, { "name":"NITINOP_0101 pssA; CDP-diacylglycerol-serine O-phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]" }, { "name":"NITINOP_2066 trpA; Tryptophan synthase alpha chain\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]" }, { "name":"NITINOP_2065 trpB; tryptophan synthase beta chain\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]" } ] }, { "name":"00270 Cysteine and methionine metabolism [PATH:nio00270]", "children":[ { "name":"NITINOP_3073 cysE; Serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]" }, { "name":"NITINOP_3041 cysK; cysteine synthase A, O-acetylserine sulfhydrolase A subunit\tK01738 cysK; cysteine synthase [EC:2.5.1.47]" }, { "name":"NITINOP_3013 metH; homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" }, { "name":"NITINOP_0345 metE; 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]" }, { "name":"NITINOP_0754 metK; ATP--methionine S-adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"NITINOP_1557 metK; methionine adenosyltransferase 1\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"NITINOP_1358 N-acyl-L-homoserine lactone synthase (modular protein)\tK22957 cviI; acyl homoserine lactone synthase [EC:2.3.1.184]" }, { "name":"NITINOP_1570 putative Adenosylhomocysteine nucleosidase\tK01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]" }, { "name":"NITINOP_1954 mtnP; S-methyl-5'-thioadenosine phosphorylase\tK00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]" }, { "name":"NITINOP_0289 conserved protein of unknown function\tK05810 LACC1; purine-nucleoside\/S-methyl-5'-thioadenosine phosphorylase \/ adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]" }, { "name":"NITINOP_2490 mtnA; Methylthioribose-1-phosphate isomerase\tK08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]" }, { "name":"NITINOP_2046 dcm; Cytosine-specific methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"NITINOP_1556 ahcY; Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"NITINOP_0767 lysC; Aspartokinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"NITINOP_0096 asd; Aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"NITINOP_0770 hom; Homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]" }, { "name":"NITINOP_1385 ilvE; putative branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_3162 ilvE; Branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_3274 putative 3-mercaptopyruvate sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]" }, { "name":"NITINOP_0980 mdh; Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"NITINOP_2643 serA; D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" } ] }, { "name":"00280 Valine, leucine and isoleucine degradation [PATH:nio00280]", "children":[ { "name":"NITINOP_1385 ilvE; putative branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_3162 ilvE; Branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_0941 pccB; Propionyl-CoA carboxylase\tK01969 MCCC2; 3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4]" }, { "name":"NITINOP_0940 putative Enoyl-CoA hydratase\tK13766 liuC; methylglutaconyl-CoA hydratase [EC:4.2.1.18]" }, { "name":"NITINOP_0939 mvaB; Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00290 Valine, leucine and isoleucine biosynthesis [PATH:nio00290]", "children":[ { "name":"NITINOP_0800 leuC; 3-isopropylmalate dehydratase (isomerase), subunit with LeuD\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"NITINOP_0801 leuD; 3-isopropylmalate isomerase subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"NITINOP_0098 leuB; 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]" }, { "name":"NITINOP_0105 ilvI; acetolactate synthase III, large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"NITINOP_0104 ilvH; acetolactate synthase III, thiamin-dependent, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" }, { "name":"NITINOP_0103 ilvC; Ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]" }, { "name":"NITINOP_2654 ilvD; Dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"NITINOP_1385 ilvE; putative branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_3162 ilvE; Branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_0100 leuA; 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]" }, { "name":"NITINOP_1137 Uncharacterized AIPM\/Hcit synthase family transferase TM_0552\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]" } ] }, { "name":"00300 Lysine biosynthesis [PATH:nio00300]", "children":[ { "name":"NITINOP_0770 hom; Homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]" }, { "name":"NITINOP_0767 lysC; Aspartokinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"NITINOP_0096 asd; Aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"NITINOP_1246 dapA; 4-hydroxy-tetrahydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]" }, { "name":"NITINOP_1245 dapB; 4-hydroxy-tetrahydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]" }, { "name":"NITINOP_1252 argD; Acetylornithine aminotransferase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]" }, { "name":"NITINOP_1362 dapF; Diaminopimelate epimerase 1\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]" }, { "name":"NITINOP_1231 dapL; LL-diaminopimelate aminotransferase\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]" }, { "name":"NITINOP_1247 lysA; Diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" }, { "name":"NITINOP_0301 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]" }, { "name":"NITINOP_0300 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]" } ] }, { "name":"00310 Lysine degradation [PATH:nio00310]", "children":[ { "name":"NITINOP_2690 Aldehyde dehydrogenase\tK26061 amaB; L-aminoadipate-semialdehyde dehydrogenase" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0187 kamA; L-lysine 2,3-aminomutase\tK01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2]" }, { "name":"NITINOP_0789 dat; D-alanine aminotransferase\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" } ] }, { "name":"00220 Arginine biosynthesis [PATH:nio00220]", "children":[ { "name":"NITINOP_1251 argF; Ornithine carbamoyltransferase\tK00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]" }, { "name":"NITINOP_1250 argG; Argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]" }, { "name":"NITINOP_1249 argH; Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]" }, { "name":"NITINOP_1205 putative Dimethylargininase\tK27545 argZ; arginine dihydrolase [EC:3.5.3.27]" }, { "name":"NITINOP_3355 ureC; Urease, alpha subunit\tK01428 ureC; urease subunit alpha [EC:3.5.1.5]" }, { "name":"NITINOP_3357 ureA; Urease gamma subunit\tK01430 ureA; urease subunit gamma [EC:3.5.1.5]" }, { "name":"NITINOP_3356 ureB; Urease, beta subunit (modular protein)\tK14048 ureAB; urease subunit gamma\/beta [EC:3.5.1.5]" }, { "name":"NITINOP_1801 purQ; Phosphoribosylformylglycinamidine synthase 1\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"NITINOP_1778 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"NITINOP_2878 carB; carbamoyl-phosphate synthase, large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"NITINOP_2881 carA; carbamoyl phosphate synthetase small subunit, glutamine amidotransferase\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]" }, { "name":"NITINOP_1303 gdhA; Glutamate dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]" }, { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_2465 argJ; Arginine biosynthesis bifunctional protein ArgJ [Includes: Glutamate N-acetyltransferase; Amino-acid acetyltransferase]\tK00620 argJ; glutamate N-acetyltransferase \/ amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]" }, { "name":"NITINOP_1069 argB; Acetylglutamate kinase\tK00930 argB; acetylglutamate kinase [EC:2.7.2.8]" }, { "name":"NITINOP_2467 argC; N-acetyl-gamma-glutamyl-phosphate reductase\tK00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]" }, { "name":"NITINOP_1252 argD; Acetylornithine aminotransferase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]" } ] }, { "name":"00330 Arginine and proline metabolism [PATH:nio00330]", "children":[ { "name":"NITINOP_0496 pdaD; putative pyruvoyl-dependent arginine decarboxylase\tK02626 pdaD; arginine decarboxylase [EC:4.1.1.19]" }, { "name":"NITINOP_1173 speB; putative agmatinase 2\tK01480 speB; agmatinase [EC:3.5.3.11]" }, { "name":"NITINOP_0495 speB; Agmatinase\tK27683 apauh; N1-aminopropylagmatine ureohydrolase [EC:3.5.3.24]" }, { "name":"NITINOP_0832 Amine oxidase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"NITINOP_1205 putative Dimethylargininase\tK27545 argZ; arginine dihydrolase [EC:3.5.3.27]" }, { "name":"NITINOP_0287 proC; Pyrroline-5-carboxylate reductase\tK00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]" }, { "name":"NITINOP_2240 putA; Bifunctional protein PutA\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]" }, { "name":"NITINOP_1206 conserved protein of unknown function\tK28013 E4.3.1.12; ornithine cyclodeaminase [EC:4.3.1.12]" }, { "name":"NITINOP_3167 proB; Glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]" }, { "name":"NITINOP_2022 proA; Gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" }, { "name":"NITINOP_2457 proA; Gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" }, { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_0789 dat; D-alanine aminotransferase\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" } ] }, { "name":"00340 Histidine metabolism [PATH:nio00340]", "children":[ { "name":"NITINOP_0122 hisG; ATP phosphoribosyltransferase\tK00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]" }, { "name":"NITINOP_2644 hisZ; ATP phosphoribosyltransferase regulatory subunit\tK02502 hisZ; ATP phosphoribosyltransferase regulatory subunit" }, { "name":"NITINOP_0113 hisI; Histidine biosynthesis bifunctional protein HisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]\tK11755 hisIE; phosphoribosyl-AMP cyclohydrolase \/ phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]" }, { "name":"NITINOP_0115 hisA; N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase\tK01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]" }, { "name":"NITINOP_0117 hisH; Imidazole glycerol phosphate synthase subunit HisH\tK02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]" }, { "name":"NITINOP_0114 hisF; imidazole glycerol phosphate synthase, catalytic subunit with HisH\tK02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]" }, { "name":"NITINOP_0120 hisB; Imidazoleglycerol-phosphate dehydratase\tK01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]" }, { "name":"NITINOP_1286 hisC; Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"NITINOP_0121 hisD; Histidinol dehydrogenase\tK00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]" }, { "name":"NITINOP_1642 putative Formimidoyltransferase-cyclodeaminase\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" }, { "name":"NITINOP_0832 Amine oxidase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" } ] }, { "name":"00350 Tyrosine metabolism [PATH:nio00350]", "children":[ { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_1286 hisC; Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"NITINOP_0952 putative dioxygenase VC_1345\tK00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]" }, { "name":"NITINOP_0832 Amine oxidase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"NITINOP_1653 adhA; putative alcohol dehydrogenase AdhA\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]" } ] }, { "name":"00360 Phenylalanine metabolism [PATH:nio00360]", "children":[ { "name":"NITINOP_0832 Amine oxidase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"NITINOP_0945 mmgB; putative 3-hydroxybutyryl-CoA dehydrogenase\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]" }, { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_1286 hisC; Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"NITINOP_0789 dat; D-alanine aminotransferase\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" } ] }, { "name":"00380 Tryptophan metabolism [PATH:nio00380]", "children":[ { "name":"NITINOP_1554 conserved protein of unknown function\tK00463 IDO; indoleamine 2,3-dioxygenase [EC:1.13.11.52]" }, { "name":"NITINOP_0666 Cyclase family protein\tK07130 kynB; arylformamidase [EC:3.5.1.9]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0832 Amine oxidase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"NITINOP_1434 katA; catalase (hydroperoxidase II)\tK03781 katE; catalase [EC:1.11.1.6]" } ] }, { "name":"00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:nio00400]", "children":[ { "name":"NITINOP_2353 aroF; 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"NITINOP_1287 aroF; Phospho-2-dehydro-3-deoxyheptonate aldolase\tK03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"NITINOP_1773 aroB; 3-dehydroquinate synthase\tK01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]" }, { "name":"NITINOP_2780 aroQ; 3-dehydroquinate dehydratase\tK03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]" }, { "name":"NITINOP_1310 aroE; Shikimate dehydrogenase\tK00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]" }, { "name":"NITINOP_1311 aroK; Shikimate kinase\tK00891 aroK; shikimate kinase [EC:2.7.1.71]" }, { "name":"NITINOP_1831 aroC; chorismate synthase\tK01736 aroC; chorismate synthase [EC:4.2.3.5]" }, { "name":"NITINOP_2060 trpE; Anthranilate synthase component 1\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]" }, { "name":"NITINOP_2061 pabA; aminodeoxychorismate synthase, subunit II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]" }, { "name":"NITINOP_1275 trpD; Anthranilate phosphoribosyltransferase\tK00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]" }, { "name":"NITINOP_2062 trpD; Anthranilate phosphoribosyltransferase\tK00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]" }, { "name":"NITINOP_2064 trpF; N-(5'-phosphoribosyl)anthranilate isomerase\tK01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]" }, { "name":"NITINOP_2063 trpC; Indole-3-glycerol phosphate synthase\tK01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]" }, { "name":"NITINOP_2066 trpA; Tryptophan synthase alpha chain\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]" }, { "name":"NITINOP_2065 trpB; tryptophan synthase beta chain\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]" }, { "name":"NITINOP_1285 pheA; P-protein [Includes: Chorismate mutase; Prephenate dehydratase]\tK14170 pheA; chorismate mutase \/ prephenate dehydratase [EC:5.4.99.5 4.2.1.51]" }, { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_1286 hisC; Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"NITINOP_0197 conserved protein of unknown function\tK18240 xanB2; chorismate lyase \/ 3-hydroxybenzoate synthase [EC:4.1.3.40 4.1.3.45]" } ] } ] }, { "name":"09106 Metabolism of other amino acids", "children":[ { "name":"00410 beta-Alanine metabolism [PATH:nio00410]", "children":[ { "name":"NITINOP_2369 panD; Aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]" }, { "name":"NITINOP_1233 panC; Pantothenate synthetase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]" } ] }, { "name":"00430 Taurine and hypotaurine metabolism [PATH:nio00430]", "children":[ { "name":"NITINOP_3220 ald; Alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]" }, { "name":"NITINOP_0681 ackA; Acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]" } ] }, { "name":"00440 Phosphonate and phosphinate metabolism [PATH:nio00440]", "children":[ { "name":"NITINOP_0319 conserved protein of unknown function\tK01841 pepM; phosphoenolpyruvate phosphomutase [EC:5.4.2.9]" }, { "name":"NITINOP_0315 phnW; 2-aminoethylphosphonate aminotransferase\tK03430 phnW; 2-aminoethylphosphonate-pyruvate transaminase [EC:2.6.1.37]" } ] }, { "name":"00450 Selenocompound metabolism [PATH:nio00450]", "children":[ { "name":"NITINOP_3013 metH; homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" }, { "name":"NITINOP_0345 metE; 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]" }, { "name":"NITINOP_0520 putative Thioredoxin\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]" }, { "name":"NITINOP_2715 trxB; thioredoxin reductase, FAD\/NAD(P)-binding\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]" }, { "name":"NITINOP_1277 cysNC; Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme)\tK00955 cysNC; bifunctional enzyme CysN\/CysC [EC:2.7.7.4 2.7.1.25]" }, { "name":"NITINOP_0857 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_1276 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_2362 metG; Methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" } ] }, { "name":"00460 Cyanoamino acid metabolism [PATH:nio00460]", "children":[ { "name":"NITINOP_1464 iaaA; Isoaspartyl peptidase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]" }, { "name":"NITINOP_1661 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" } ] }, { "name":"00470 D-Amino acid metabolism [PATH:nio00470]", "children":[ { "name":"NITINOP_2459 alr; Alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]" }, { "name":"NITINOP_0789 dat; D-alanine aminotransferase\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" }, { "name":"NITINOP_0293 ddlB; D-alanine:D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"NITINOP_1801 purQ; Phosphoribosylformylglycinamidine synthase 1\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"NITINOP_0298 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"NITINOP_1362 dapF; Diaminopimelate epimerase 1\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]" }, { "name":"NITINOP_1247 lysA; Diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" } ] }, { "name":"00480 Glutathione metabolism [PATH:nio00480]", "children":[ { "name":"NITINOP_3369 conserved protein of unknown function\tK07160 pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9]" }, { "name":"NITINOP_1097 pepA; putative cytosol aminopeptidase\tK01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]" }, { "name":"NITINOP_1162 putative Peptidase M\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]" }, { "name":"NITINOP_0225 idh; Isocitrate dehydrogenase (NADP(+))\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"NITINOP_2010 yqeC; putative 6-phosphogluconate dehydrogenase YqeC\tK00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]" }, { "name":"NITINOP_0665 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"NITINOP_2009 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" } ] } ] }, { "name":"09107 Glycan biosynthesis and metabolism", "children":[ { "name":"00520 Amino sugar and nucleotide sugar metabolism [PATH:nio00520]", "children":[ { "name":"NITINOP_1191 anmK; Anhydro-N-acetylmuramic acid kinase\tK09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170]" }, { "name":"NITINOP_3385 putative Phosphotransferase\tK07102 amgK; N-acetylmuramate 1-kinase [EC:2.7.1.221]" }, { "name":"NITINOP_2366 glmU; fused N-acetyl glucosamine-1-phosphate uridyltransferase; glucosamine-1-phosphate acetyl transferase\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]" }, { "name":"NITINOP_0413 UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]" }, { "name":"NITINOP_0123 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"NITINOP_0294 murB; UDP-N-acetylenolpyruvoylglucosamine reductase 2\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"NITINOP_1096 nagZ; Beta-N-acetylglucosaminidase\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]" }, { "name":"NITINOP_2488 glmM; phosphoglucosamine mutase\tK03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]" }, { "name":"NITINOP_2367 glmS; L-glutamine:D-fructose-6-phosphate aminotransferase\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"NITINOP_0912 putative Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"NITINOP_3081 cpsB; mannose-1-phosphate guanyltransferase\tK16011 algA; mannose-1-phosphate guanylyltransferase \/ mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]" }, { "name":"NITINOP_1650 Uncharacterized 37.6 kDa protein in cld 5'region\tK08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]" }, { "name":"NITINOP_0914 glk; Glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"NITINOP_2245 pgm; Phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"NITINOP_3139 yngB; putative UTP--glucose-1-phosphate uridylyltransferase YngB\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"NITINOP_0144 rkpK; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"NITINOP_0007 galT; Galactose-1-phosphate uridylyltransferase\tK00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]" }, { "name":"NITINOP_1404 putative UDP-glucose 4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"NITINOP_3180 galE; UDP-galactose-4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"NITINOP_3384 putative Nucleotidyl transferase\tK00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]" }, { "name":"NITINOP_2252 rfbF; Glucose-1-phosphate cytidylyltransferase\tK00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]" }, { "name":"NITINOP_3058 glgC; Glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]" }, { "name":"NITINOP_3111 rmlA; dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase)\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" } ] }, { "name":"00541 Biosynthesis of various nucleotide sugars [PATH:nio00541]", "children":[ { "name":"NITINOP_2366 glmU; fused N-acetyl glucosamine-1-phosphate uridyltransferase; glucosamine-1-phosphate acetyl transferase\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]" }, { "name":"NITINOP_2456 capL; Protein CapL\tK02474 wbpO; UDP-N-acetyl-D-glucosamine\/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]" }, { "name":"NITINOP_2867 kdsD; D-arabinose 5-phosphate isomerase\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]" }, { "name":"NITINOP_2868 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]" }, { "name":"NITINOP_3082 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]" }, { "name":"NITINOP_2870 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]" }, { "name":"NITINOP_0413 UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]" }, { "name":"NITINOP_1473 gmhA; Phosphoheptose isomerase\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]" }, { "name":"NITINOP_2871 rfaEa; D-beta-D-heptose 7-phosphate kinase, domain I of bifunctional protein HldE\tK21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]" }, { "name":"NITINOP_1470 rfaEb; D-beta-D-heptose 1-phosphate adenosyltransferase\tK21345 rfaE2; D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase [EC:2.7.7.70]" }, { "name":"NITINOP_0355 hldD; ADP-L-glycero-D-manno-heptose-6-epimerase\tK03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]" }, { "name":"NITINOP_3139 yngB; putative UTP--glucose-1-phosphate uridylyltransferase YngB\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"NITINOP_0144 rkpK; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"NITINOP_2252 rfbF; Glucose-1-phosphate cytidylyltransferase\tK00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]" }, { "name":"NITINOP_2253 rfbG; CDP-glucose 4,6-dehydratase\tK01709 rfbG; CDP-glucose 4,6-dehydratase [EC:4.2.1.45]" }, { "name":"NITINOP_2254 rfbH; Lipopolysaccharide biosynthesis protein RfbH\tK12452 ascC; CDP-4-dehydro-6-deoxyglucose reductase, E1 [EC:1.17.1.1]" }, { "name":"NITINOP_3111 rmlA; dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase)\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"NITINOP_3112 rmlB; dTDP-glucose 4,6 dehydratase, NAD(P)-binding\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"NITINOP_2255 dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"NITINOP_3110 rmlC; dTDP-4-deoxyrhamnose-3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"NITINOP_3083 rfbD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" }, { "name":"NITINOP_3384 putative Nucleotidyl transferase\tK00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]" }, { "name":"NITINOP_3081 cpsB; mannose-1-phosphate guanyltransferase\tK16011 algA; mannose-1-phosphate guanylyltransferase \/ mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]" }, { "name":"NITINOP_3114 gmd; GDP-D-mannose dehydratase, NAD(P)-binding\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]" }, { "name":"NITINOP_3113 fcl; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]" } ] }, { "name":"00510 N-Glycan biosynthesis" }, { "name":"00513 Various types of N-glycan biosynthesis" }, { "name":"00512 Mucin type O-glycan biosynthesis" }, { "name":"00515 Mannose type O-glycan biosynthesis" }, { "name":"00514 Other types of O-glycan biosynthesis" }, { "name":"00532 Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate" }, { "name":"00534 Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin" }, { "name":"00533 Glycosaminoglycan biosynthesis - keratan sulfate" }, { "name":"00531 Glycosaminoglycan degradation" }, { "name":"00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" }, { "name":"00601 Glycosphingolipid biosynthesis - lacto and neolacto series" }, { "name":"00603 Glycosphingolipid biosynthesis - globo and isoglobo series" }, { "name":"00604 Glycosphingolipid biosynthesis - ganglio series" }, { "name":"00511 Other glycan degradation" }, { "name":"00540 Lipopolysaccharide biosynthesis [PATH:nio00540]", "children":[ { "name":"NITINOP_3133 lpxA; UDP-N-acetylglucosamine acetyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" }, { "name":"NITINOP_1448 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase\tK02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]" }, { "name":"NITINOP_2564 lpxD; UDP-3-O-acylglucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]" }, { "name":"NITINOP_3132 conserved protein of unknown function\tK09949 lpxI; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]" }, { "name":"NITINOP_3130 lpxB; Lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]" }, { "name":"NITINOP_3125 lpxK; Tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]" }, { "name":"NITINOP_3126 waaA; 3-deoxy-D-manno-octulosonic-acid transferase\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]" }, { "name":"NITINOP_0025 exported protein of unknown function\tK12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]" }, { "name":"NITINOP_3124 gmhB; Lipopolysaccharide heptosyltransferase II and D, D-heptose 1,7-bisphosphate phosphatase (Modular protein)\tK02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]" }, { "name":"NITINOP_3087 putative lipopolysaccharide heptosyltransferase III\tK02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25]" } ] }, { "name":"00542 O-Antigen repeat unit biosynthesis [PATH:nio00542]", "children":[ { "name":"NITINOP_0411 putative Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (Modular protein)\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00550 Peptidoglycan biosynthesis [PATH:nio00550]", "children":[ { "name":"NITINOP_0123 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"NITINOP_0294 murB; UDP-N-acetylenolpyruvoylglucosamine reductase 2\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"NITINOP_0295 murC; UDP-N-acetylmuramate:L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]" }, { "name":"NITINOP_0298 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"NITINOP_0301 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]" }, { "name":"NITINOP_0293 ddlB; D-alanine:D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"NITINOP_0300 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]" }, { "name":"NITINOP_1984 ispU; undecaprenyl pyrophosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" }, { "name":"NITINOP_1928 uppP; Undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"NITINOP_0299 mraY; phospho-N-acetylmuramoyl-pentapeptide transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"NITINOP_0296 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" }, { "name":"NITINOP_1465 mtgA; Monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0516 mrcA; Penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"NITINOP_1542 putative Penicillin-binding protein 1B\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]" }, { "name":"NITINOP_0297 ftsW; integral membrane protein involved in stabilizing FstZ ring during cell division\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0085 mrdB; cell wall shape-determining protein\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0086 mrdA; Penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" }, { "name":"NITINOP_0302 ftsI; Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" }, { "name":"NITINOP_1300 putative D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]" }, { "name":"NITINOP_0284 putative Esterase, beta-lactamase family\tK21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]" } ] }, { "name":"00552 Teichoic acid biosynthesis [PATH:nio00552]", "children":[ { "name":"NITINOP_1928 uppP; Undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"NITINOP_0411 putative Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (Modular protein)\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00571 Lipoarabinomannan (LAM) biosynthesis" }, { "name":"00572 Arabinogalactan biosynthesis - Mycobacterium", "children":[ { "name":"NITINOP_0411 putative Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (Modular protein)\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00543 Exopolysaccharide biosynthesis [PATH:nio00543]", "children":[ { "name":"NITINOP_0411 putative Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (Modular protein)\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"NITINOP_3073 cysE; Serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]" } ] } ] }, { "name":"09108 Metabolism of cofactors and vitamins", "children":[ { "name":"00730 Thiamine metabolism [PATH:nio00730]", "children":[ { "name":"NITINOP_1922 thiC; thiamin (pyrimidine moiety) biosynthesis protein\tK03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]" }, { "name":"NITINOP_0039 thiD; Phosphomethylpyrimidine kinase\tK00941 thiD; hydroxymethylpyrimidine\/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]" }, { "name":"NITINOP_0510 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"NITINOP_2716 thiI; putative tRNA sulfurtransferase\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]" }, { "name":"NITINOP_1577 dxs; 1-deoxy-D-xylulose-5-phosphate synthase 1\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]" }, { "name":"NITINOP_3243 thiG; thiamin biosynthesis ThiGH complex subunit\tK03149 thiG; thiazole synthase [EC:2.8.1.10]" }, { "name":"NITINOP_1921 putative ribose 1,5-bisphosphate isomerase\tK22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]" }, { "name":"NITINOP_2236 thiE; Thiamine-phosphate synthase\tK00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]" }, { "name":"NITINOP_3242 thiE; putative thiamine-phosphate synthase\tK00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]" }, { "name":"NITINOP_3141 thiL; Thiamine-monophosphate kinase\tK00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]" }, { "name":"NITINOP_1752 adk; Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]" }, { "name":"NITINOP_2201 putative Thiaminase\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]" } ] }, { "name":"00740 Riboflavin metabolism [PATH:nio00740]", "children":[ { "name":"NITINOP_1793 ribBA; Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase-2]\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"NITINOP_2181 ribD; Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase]\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]" }, { "name":"NITINOP_1794 ribE; riboflavin synthase beta chain\tK00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]" }, { "name":"NITINOP_2184 ribE; Riboflavin synthase\tK00793 ribE; riboflavin synthase [EC:2.5.1.9]" }, { "name":"NITINOP_2482 ribF; Riboflavin biosynthesis protein RibF\tK11753 ribF; riboflavin kinase \/ FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]" }, { "name":"NITINOP_0848 nudF; ADP-ribose pyrophosphatase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]" } ] }, { "name":"00750 Vitamin B6 metabolism [PATH:nio00750]", "children":[ { "name":"NITINOP_1198 pdxA; 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent\tK00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262]" }, { "name":"NITINOP_0773 pdxJ; pyridoxine 5'-phosphate synthase\tK03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]" }, { "name":"NITINOP_0769 thrC; Threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" }, { "name":"NITINOP_3043 thrC; Threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" } ] }, { "name":"00760 Nicotinate and nicotinamide metabolism [PATH:nio00760]", "children":[ { "name":"NITINOP_1383 nadB; L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]" }, { "name":"NITINOP_1924 nadA; Quinolinate synthase A\tK03517 nadA; quinolinate synthase [EC:2.5.1.72]" }, { "name":"NITINOP_2729 nadC; putative nicotinate-nucleotide pyrophosphorylase [carboxylating]\tK00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]" }, { "name":"NITINOP_0550 pncB; Nicotinate phosphoribosyltransferase pncB2\tK00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]" }, { "name":"NITINOP_3196 ushA; 5'-nucleotidase\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]" }, { "name":"NITINOP_1140 surE; 5'-nucleotidase SurE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]" }, { "name":"NITINOP_3168 nadD; putative nicotinate-nucleotide adenylyltransferase\tK00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]" }, { "name":"NITINOP_2226 mazG; Nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"NITINOP_2397 nadE; NH(3)-dependent NAD(+) synthetase\tK01916 nadE; NAD+ synthase [EC:6.3.1.5]" }, { "name":"NITINOP_1774 nadE; putative glutamine-dependent NAD(+) synthetase\tK01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]" }, { "name":"NITINOP_0549 pncA; Pyrazinamidase\/nicotinamidase (PZAase) (Nicotine deamidase) (NAMase)\tK08281 pncA; nicotinamidase\/pyrazinamidase [EC:3.5.1.19 3.5.1.-]" }, { "name":"NITINOP_2724 cobB; NAD-dependent protein deacylase\tK12410 cobB; NAD-dependent protein deacetylase\/lipoamidase [EC:2.3.1.286 2.3.1.313]" }, { "name":"NITINOP_2790 ppnK; NAD(+) kinase\tK00858 ppnK; NAD+ kinase [EC:2.7.1.23]" }, { "name":"NITINOP_2164 sthA; putative soluble pyridine nucleotide transhydrogenase\tK00322 sthA; NAD(P) transhydrogenase [EC:1.6.1.1]" }, { "name":"NITINOP_2202 sthA; putative soluble pyridine nucleotide transhydrogenase\tK00322 sthA; NAD(P) transhydrogenase [EC:1.6.1.1]" }, { "name":"NITINOP_0702 pntB; pyridine nucleotide transhydrogenase, beta subunit\tK00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1]" } ] }, { "name":"00770 Pantothenate and CoA biosynthesis [PATH:nio00770]", "children":[ { "name":"NITINOP_0105 ilvI; acetolactate synthase III, large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"NITINOP_0104 ilvH; acetolactate synthase III, thiamin-dependent, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" }, { "name":"NITINOP_0103 ilvC; Ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]" }, { "name":"NITINOP_2654 ilvD; Dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"NITINOP_0247 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase\tK00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]" }, { "name":"NITINOP_2723 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]" }, { "name":"NITINOP_1233 panC; Pantothenate synthetase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]" }, { "name":"NITINOP_2542 coaX; Type III pantothenate kinase\tK03525 coaX; type III pantothenate kinase [EC:2.7.1.33]" }, { "name":"NITINOP_2782 dfp; fused 4'-phosphopantothenoylcysteine decarboxylase; phosphopantothenoylcysteine synthetase, FMN-binding\tK13038 coaBC; phosphopantothenoylcysteine decarboxylase \/ phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]" }, { "name":"NITINOP_2226 mazG; Nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"NITINOP_2667 coaD; pantetheine-phosphate adenylyltransferase\tK00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]" }, { "name":"NITINOP_2714 coaE; Dephospho-CoA kinase\tK00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]" }, { "name":"NITINOP_2717 putative 4'-phosphopantetheinyl transferase HetI\tK06133 LYS5; 4'-phosphopantetheinyl transferase [EC:2.7.8.-]" }, { "name":"NITINOP_1385 ilvE; putative branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_3162 ilvE; Branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_2369 panD; Aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]" } ] }, { "name":"00780 Biotin metabolism [PATH:nio00780]", "children":[ { "name":"NITINOP_0204 Beta-ketoacyl synthase\tK00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]" }, { "name":"NITINOP_0256 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"NITINOP_2566 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"NITINOP_0161 Uncharacterized oxidoreductase MexAM1_META1p0182\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0192 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0201 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0258 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2238 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2516 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0208 protein of unknown function\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"NITINOP_3134 fabZ; (3R)-hydroxymyristol acyl carrier protein dehydratase\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"NITINOP_0846 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]" }, { "name":"NITINOP_2638 bioF; 8-amino-7-oxononanoate synthase\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]" }, { "name":"NITINOP_2875 bioA; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase\tK00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]" }, { "name":"NITINOP_2237 bioD; ATP-dependent dethiobiotin synthetase BioD\tK01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]" }, { "name":"NITINOP_3171 bioB; Biotin synthase\tK01012 bioB; biotin synthase [EC:2.8.1.6]" }, { "name":"NITINOP_2730 putative Biotin-(Acetyl-CoA-carboxylase) ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]" } ] }, { "name":"00785 Lipoic acid metabolism [PATH:nio00785]", "children":[ { "name":"NITINOP_1304 lipB; Octanoyltransferase\tK03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]" }, { "name":"NITINOP_2244 lipA; Lipoyl synthase\tK03644 lipA; lipoyl synthase [EC:2.8.1.8]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_1005 gcvP; glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"NITINOP_0849 gcvT; Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"NITINOP_2492 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" } ] }, { "name":"00790 Folate biosynthesis [PATH:nio00790]", "children":[ { "name":"NITINOP_0974 folE; GTP cyclohydrolase 1\tK01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]" }, { "name":"NITINOP_1902 Phosphodiesterase\/alkaline phosphatase D\tK01113 phoD; alkaline phosphatase D [EC:3.1.3.1]" }, { "name":"NITINOP_1232 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridinediphosphokinase\tK00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]" }, { "name":"NITINOP_2487 folP; 7,8-dihydropteroate synthase\tK00796 folP; dihydropteroate synthase [EC:2.5.1.15]" }, { "name":"NITINOP_2819 folC; Bifunctional protein FolC: Folylpolyglutamate synthase and Dihydrofolate synthase\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]" }, { "name":"NITINOP_1793 ribBA; Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase-2]\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"NITINOP_1386 trpE; Anthranilate synthase component 1\tK01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]" }, { "name":"NITINOP_0531 putative 6-pyruvoyl-tetrahydropterin synthase (Modular protein)\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"NITINOP_0975 pts; 6-carboxy-5,6,7,8-tetrahydropterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"NITINOP_1440 putative pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]" }, { "name":"NITINOP_1098 queE; 7-carboxy-7-deazaguanine synthase\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]" }, { "name":"NITINOP_3214 queC; 7-cyano-7-deazaguanine synthase\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]" }, { "name":"NITINOP_0245 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase\tK09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]" }, { "name":"NITINOP_2822 moaA; Cyclic pyranopterin monophosphate synthase 3\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]" }, { "name":"NITINOP_2824 moaC; molybdopterin biosynthesis, protein C\tK03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]" }, { "name":"NITINOP_2823 Molybdopterin synthase catalytic subunit (modular protein)\tK21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12]" }, { "name":"NITINOP_2903 moaB; Molybdenum cofactor biosynthesis protein B\tK03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]" }, { "name":"NITINOP_1965 moeA; Molybdopterin biosynthesis protein MoeA\tK03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]" }, { "name":"NITINOP_3182 putative Transcriptional regulator ModE\tK03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]" }, { "name":"NITINOP_3334 mobA; putative molybdenum cofactor guanylyltransferase\tK03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]" } ] }, { "name":"00670 One carbon pool by folate [PATH:nio00670]", "children":[ { "name":"NITINOP_1513 fhs; Formate--tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]" }, { "name":"NITINOP_0249 folD; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase and 5,10-methylene-tetrahydrofolate cyclohydrolase\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]" }, { "name":"NITINOP_1661 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"NITINOP_2233 purN; phosphoribosylglycinamide formyltransferase 1\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]" }, { "name":"NITINOP_2673 purH; fused IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"NITINOP_1642 putative Formimidoyltransferase-cyclodeaminase\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" }, { "name":"NITINOP_0849 gcvT; Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"NITINOP_3013 metH; homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" }, { "name":"NITINOP_1058 purU; Formyltetrahydrofolate deformylase\tK01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]" }, { "name":"NITINOP_0248 metF; Methylenetetrahydrofolate reductase\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]" }, { "name":"NITINOP_0754 metK; ATP--methionine S-adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"NITINOP_1557 metK; methionine adenosyltransferase 1\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"NITINOP_1556 ahcY; Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"NITINOP_1005 gcvP; glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_2492 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" } ] }, { "name":"00830 Retinol metabolism" }, { "name":"00860 Porphyrin metabolism [PATH:nio00860]", "children":[ { "name":"NITINOP_0506 gltX; Glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"NITINOP_2477 hemA; Glutamyl-tRNA reductase\tK02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]" }, { "name":"NITINOP_1492 hemL; glutamate-1-semialdehyde aminotransferase (aminomutase)\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]" }, { "name":"NITINOP_1691 Aminotransferase class-III (modular protein)\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]" }, { "name":"NITINOP_2481 hemB; porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]" }, { "name":"NITINOP_2478 hemC; hydroxymethylbilane synthase\tK01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]" }, { "name":"NITINOP_2217 hemE; Uroporphyrinogen decarboxylase\tK01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]" }, { "name":"NITINOP_2219 hemY; Protoporphyrinogen oxidase\tK00231 PPOX; protoporphyrinogen\/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15]" }, { "name":"NITINOP_2218 hemH; Ferrochelatase\tK01772 hemH; protoporphyrin\/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]" }, { "name":"NITINOP_2479 hemD; Porphyrin biosynthesis protein HemD\tK13542 cobA-hemD; uroporphyrinogen III methyltransferase \/ synthase [EC:2.1.1.107 4.2.1.75]" }, { "name":"NITINOP_2887 putative Precorrin-2 dehydrogenase\tK24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]" }, { "name":"NITINOP_1331 putative Radical SAM superfamily protein, Coenzyme PQQ synthesis protein E\tK22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]" }, { "name":"NITINOP_2551 yvqK; Cob(I)yrinic acid a,c-diamide adenosyltransferase\tK00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]" }, { "name":"NITINOP_2555 cobD; Cobalamin biosynthesis protein CobD\tK02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]" }, { "name":"NITINOP_2552 cobU; bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase\tK02231 cobP; adenosylcobinamide kinase \/ adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62]" }, { "name":"NITINOP_2554 cobS; Cobalamin synthase\tK02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]" }, { "name":"NITINOP_2553 cobT; nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase\tK00768 E2.4.2.21; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21]" }, { "name":"NITINOP_2556 cobD; Threonine-phosphate decarboxylase\tK04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]" }, { "name":"NITINOP_1863 bfr; Bacterioferritin\tK03594 bfr; bacterioferritin [EC:1.16.3.1]" }, { "name":"NITINOP_1864 bfrA; Bacterioferritin\tK03594 bfr; bacterioferritin [EC:1.16.3.1]" } ] }, { "name":"00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:nio00130]", "children":[ { "name":"NITINOP_0197 conserved protein of unknown function\tK18240 xanB2; chorismate lyase \/ 3-hydroxybenzoate synthase [EC:4.1.3.40 4.1.3.45]" }, { "name":"NITINOP_1600 ubiA; 4-hydroxybenzoate octaprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]" }, { "name":"NITINOP_0211 Methyltransferase\tK03183 ubiE; demethylmenaquinone methyltransferase \/ 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]" }, { "name":"NITINOP_1333 ubiE; Ubiquinone\/menaquinone biosynthesis C-methyltransferase UbiE\tK03183 ubiE; demethylmenaquinone methyltransferase \/ 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]" }, { "name":"NITINOP_3284 wrbA; NAD(P)H:quinone oxidoreductase WrbA\tK03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]" }, { "name":"NITINOP_0343 Methylase involved in ubiquinone\/menaquinone biosynthesis\tK18534 K18534; MPBQ\/MSBQ methyltransferase [EC:2.1.1.295]" } ] } ] }, { "name":"09109 Metabolism of terpenoids and polyketides", "children":[ { "name":"00900 Terpenoid backbone biosynthesis [PATH:nio00900]", "children":[ { "name":"NITINOP_1577 dxs; 1-deoxy-D-xylulose-5-phosphate synthase 1\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]" }, { "name":"NITINOP_1982 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase\tK00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]" }, { "name":"NITINOP_3075 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase\tK00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]" }, { "name":"NITINOP_0278 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase\tK00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]" }, { "name":"NITINOP_3074 ispF; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase\tK01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]" }, { "name":"NITINOP_1578 ispG; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase\tK03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]" }, { "name":"NITINOP_1567 ispH; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein\tK03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0337 Farnesyl diphosphate synthase (modular protein)\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"NITINOP_3381 ispB; Octaprenyl-diphosphate synthase\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]" }, { "name":"NITINOP_1984 ispU; undecaprenyl pyrophosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" } ] }, { "name":"00902 Monoterpenoid biosynthesis" }, { "name":"00909 Sesquiterpenoid and triterpenoid biosynthesis [PATH:nio00909]", "children":[ { "name":"NITINOP_3226 Farnesyl-diphosphate farnesyltransferase\tK00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]" }, { "name":"NITINOP_1569 shc; Squalene--hopene cyclase\tK06045 shc; squalene-hopene\/tetraprenyl-beta-curcumene cyclase [EC:5.4.99.17 4.2.1.129]" } ] }, { "name":"00904 Diterpenoid biosynthesis" }, { "name":"00906 Carotenoid biosynthesis [PATH:nio00906]", "children":[ { "name":"NITINOP_1991 crtB; Phytoene synthase\tK02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]" } ] }, { "name":"00905 Brassinosteroid biosynthesis" }, { "name":"00981 Insect hormone biosynthesis" }, { "name":"00908 Zeatin biosynthesis" }, { "name":"00903 Limonene degradation" }, { "name":"00907 Pinene, camphor and geraniol degradation", "children":[ { "name":"NITINOP_0939 mvaB; Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" } ] }, { "name":"01052 Type I polyketide structures" }, { "name":"00522 Biosynthesis of 12-, 14- and 16-membered macrolides" }, { "name":"01051 Biosynthesis of ansamycins", "children":[ { "name":"NITINOP_2171 tktA; Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" } ] }, { "name":"01059 Biosynthesis of enediyne antibiotics" }, { "name":"01056 Biosynthesis of type II polyketide backbone" }, { "name":"01057 Biosynthesis of type II polyketide products" }, { "name":"00253 Tetracycline biosynthesis" }, { "name":"00523 Polyketide sugar unit biosynthesis [PATH:nio00523]", "children":[ { "name":"NITINOP_3111 rmlA; dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase)\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"NITINOP_3112 rmlB; dTDP-glucose 4,6 dehydratase, NAD(P)-binding\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"NITINOP_2255 dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"NITINOP_3110 rmlC; dTDP-4-deoxyrhamnose-3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"NITINOP_3083 rfbD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" } ] }, { "name":"01054 Nonribosomal peptide structures" }, { "name":"01053 Biosynthesis of siderophore group nonribosomal peptides" }, { "name":"01055 Biosynthesis of vancomycin group antibiotics", "children":[ { "name":"NITINOP_3112 rmlB; dTDP-glucose 4,6 dehydratase, NAD(P)-binding\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" } ] } ] }, { "name":"09110 Biosynthesis of other secondary metabolites", "children":[ { "name":"00940 Phenylpropanoid biosynthesis" }, { "name":"00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis" }, { "name":"00941 Flavonoid biosynthesis" }, { "name":"00944 Flavone and flavonol biosynthesis" }, { "name":"00942 Anthocyanin biosynthesis" }, { "name":"00943 Isoflavonoid biosynthesis" }, { "name":"00946 Degradation of flavonoids" }, { "name":"00901 Indole alkaloid biosynthesis" }, { "name":"00403 Indole diterpene alkaloid biosynthesis" }, { "name":"00950 Isoquinoline alkaloid biosynthesis" }, { "name":"00960 Tropane, piperidine and pyridine alkaloid biosynthesis" }, { "name":"00996 Biosynthesis of various alkaloids" }, { "name":"00232 Caffeine metabolism" }, { "name":"00965 Betalain biosynthesis" }, { "name":"00966 Glucosinolate biosynthesis" }, { "name":"00402 Benzoxazinoid biosynthesis" }, { "name":"00311 Penicillin and cephalosporin biosynthesis" }, { "name":"00332 Carbapenem biosynthesis [PATH:nio00332]", "children":[ { "name":"NITINOP_3167 proB; Glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]" }, { "name":"NITINOP_2022 proA; Gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" }, { "name":"NITINOP_2457 proA; Gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" } ] }, { "name":"00261 Monobactam biosynthesis [PATH:nio00261]", "children":[ { "name":"NITINOP_1277 cysNC; Sulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme)\tK00955 cysNC; bifunctional enzyme CysN\/CysC [EC:2.7.7.4 2.7.1.25]" }, { "name":"NITINOP_0857 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_1276 cysD; Sulfate adenylyltransferase, subunit 2\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]" }, { "name":"NITINOP_0767 lysC; Aspartokinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"NITINOP_0096 asd; Aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"NITINOP_1246 dapA; 4-hydroxy-tetrahydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]" }, { "name":"NITINOP_1245 dapB; 4-hydroxy-tetrahydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]" } ] }, { "name":"00331 Clavulanic acid biosynthesis" }, { "name":"00521 Streptomycin biosynthesis [PATH:nio00521]", "children":[ { "name":"NITINOP_0914 glk; Glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"NITINOP_2245 pgm; Phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]" }, { "name":"NITINOP_3080 manB_pgm; bifunctional Phosphoglucomutase\/Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"NITINOP_1445 suhB; Inositol-1-monophosphatase\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]" }, { "name":"NITINOP_3111 rmlA; dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase)\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"NITINOP_3112 rmlB; dTDP-glucose 4,6 dehydratase, NAD(P)-binding\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"NITINOP_2255 dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"NITINOP_3110 rmlC; dTDP-4-deoxyrhamnose-3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"NITINOP_3083 rfbD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" } ] }, { "name":"00524 Neomycin, kanamycin and gentamicin biosynthesis", "children":[ { "name":"NITINOP_0914 glk; Glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" } ] }, { "name":"00525 Acarbose and validamycin biosynthesis [PATH:nio00525]", "children":[ { "name":"NITINOP_3111 rmlA; dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase)\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"NITINOP_3112 rmlB; dTDP-glucose 4,6 dehydratase, NAD(P)-binding\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" } ] }, { "name":"00401 Novobiocin biosynthesis [PATH:nio00401]", "children":[ { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_1286 hisC; Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" } ] }, { "name":"00404 Staurosporine biosynthesis" }, { "name":"00405 Phenazine biosynthesis [PATH:nio00405]", "children":[ { "name":"NITINOP_2909 yddE; Uncharacterized isomerase\tK06998 phzF; trans-2,3-dihydro-3-hydroxyanthranilate isomerase [EC:5.3.3.17]" }, { "name":"NITINOP_2060 trpE; Anthranilate synthase component 1\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]" }, { "name":"NITINOP_2061 pabA; aminodeoxychorismate synthase, subunit II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]" } ] }, { "name":"00333 Prodigiosin biosynthesis", "children":[ { "name":"NITINOP_0259 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"NITINOP_0161 Uncharacterized oxidoreductase MexAM1_META1p0182\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0192 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0201 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0258 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2238 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2516 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0846 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]" } ] }, { "name":"00254 Aflatoxin biosynthesis" }, { "name":"00975 Biosynthesis of various siderophores" }, { "name":"00998 Biosynthesis of various antibiotics [PATH:nio00998]", "children":[ { "name":"NITINOP_0210 Acyl carrier protein\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_0257 acpP; acyl carrier protein (ACP)\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_2565 Acyl carrier protein (modular protein)\tK02078 acpP; acyl carrier protein" }, { "name":"NITINOP_0319 conserved protein of unknown function\tK01841 pepM; phosphoenolpyruvate phosphomutase [EC:5.4.2.9]" } ] }, { "name":"00999 Biosynthesis of various plant secondary metabolites [PATH:nio00999]", "children":[ { "name":"NITINOP_0754 metK; ATP--methionine S-adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"NITINOP_1557 metK; methionine adenosyltransferase 1\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"NITINOP_1310 aroE; Shikimate dehydrogenase\tK00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]" } ] }, { "name":"00997 Biosynthesis of various other secondary metabolites" } ] }, { "name":"09111 Xenobiotics biodegradation and metabolism", "children":[ { "name":"00362 Benzoate degradation [PATH:nio00362]", "children":[ { "name":"NITINOP_0173 putative Glyoxalase\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]" }, { "name":"NITINOP_0508 fdxB; 2Fe-2S ferredoxin\tK04755 fdx; ferredoxin, 2Fe-2S" }, { "name":"NITINOP_0977 fdx; 2Fe-2S ferredoxin\tK04755 fdx; ferredoxin, 2Fe-2S" }, { "name":"NITINOP_0937 paaF; enoyl-CoA hydratase-isomerase\tK13767 fadB; enoyl-CoA hydratase [EC:4.2.1.17]" }, { "name":"NITINOP_0945 mmgB; putative 3-hydroxybutyryl-CoA dehydrogenase\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00627 Aminobenzoate degradation", "children":[ { "name":"NITINOP_3218 acyP; Acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]" } ] }, { "name":"00364 Fluorobenzoate degradation" }, { "name":"00625 Chloroalkane and chloroalkene degradation [PATH:nio00625]", "children":[ { "name":"NITINOP_1653 adhA; putative alcohol dehydrogenase AdhA\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]" } ] }, { "name":"00361 Chlorocyclohexane and chlorobenzene degradation", "children":[ { "name":"NITINOP_0173 putative Glyoxalase\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]" } ] }, { "name":"00623 Toluene degradation" }, { "name":"00622 Xylene degradation [PATH:nio00622]", "children":[ { "name":"NITINOP_0173 putative Glyoxalase\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]" } ] }, { "name":"00633 Nitrotoluene degradation", "children":[ { "name":"NITINOP_0238 forA; 2-oxoglutarate:ferredoxin oxidoredutase alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1630 porA; Pyruvate:ferredoxin oxidoreductase, alpha subunit\tK00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0242 forB; 2-oxoglutarate:ferredoxin oxidoredutase beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1629 porB; Pyruvate:ferredoxin oxidoreductase, beta subunit\tK00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]" }, { "name":"NITINOP_0241 forC; 2-oxoglutarate:ferredoxin oxidoredutase gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1628 porC; Pyruvate:ferredoxin oxidoreductase, gamma subunit\tK00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]" }, { "name":"NITINOP_1627 porE; Pyruvate:ferredoxin oxidoreductase, epsilon subunit\tK00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]" } ] }, { "name":"00642 Ethylbenzene degradation" }, { "name":"00643 Styrene degradation [PATH:nio00643]", "children":[ { "name":"NITINOP_0952 putative dioxygenase VC_1345\tK00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]" }, { "name":"NITINOP_0173 putative Glyoxalase\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]" } ] }, { "name":"00791 Atrazine degradation", "children":[ { "name":"NITINOP_3355 ureC; Urease, alpha subunit\tK01428 ureC; urease subunit alpha [EC:3.5.1.5]" }, { "name":"NITINOP_3357 ureA; Urease gamma subunit\tK01430 ureA; urease subunit gamma [EC:3.5.1.5]" }, { "name":"NITINOP_3356 ureB; Urease, beta subunit (modular protein)\tK14048 ureAB; urease subunit gamma\/beta [EC:3.5.1.5]" } ] }, { "name":"00930 Caprolactam degradation" }, { "name":"00363 Bisphenol degradation" }, { "name":"00621 Dioxin degradation" }, { "name":"00626 Naphthalene degradation [PATH:nio00626]", "children":[ { "name":"NITINOP_1653 adhA; putative alcohol dehydrogenase AdhA\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]" } ] }, { "name":"00624 Polycyclic aromatic hydrocarbon degradation" }, { "name":"00365 Furfural degradation" }, { "name":"00984 Steroid degradation" }, { "name":"00980 Metabolism of xenobiotics by cytochrome P450" }, { "name":"00982 Drug metabolism - cytochrome P450" }, { "name":"00983 Drug metabolism - other enzymes" } ] }, { "name":"09112 Not included in regular maps", "children":[ { "name":"09113 Global maps only" } ] } ] }, { "name":"09120 Genetic Information Processing", "children":[ { "name":"09121 Transcription", "children":[ { "name":"03020 RNA polymerase [PATH:nio03020]", "children":[ { "name":"NITINOP_1722 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"NITINOP_1723 rpoC; RNA polymerase, beta prime subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"NITINOP_1759 rpoA; RNA polymerase, alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"NITINOP_2783 rpoZ; DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]" } ] }, { "name":"03022 Basal transcription factors" }, { "name":"03040 Spliceosome" } ] }, { "name":"09122 Translation", "children":[ { "name":"03010 Ribosome [PATH:nio03010]", "children":[ { "name":"NITINOP_23s_rRNA1 ribosomal RNA 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"NITINOP_5s_rRNA_1 ribosomal RNA 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"NITINOP_1292 rpsA; 30S ribosomal subunit protein S1\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"NITINOP_2463 rpsB; 30S ribosomal subunit protein S2\tK02967 RP-S2; small subunit ribosomal protein S2" }, { "name":"NITINOP_1735 rpsC; 30S ribosomal subunit protein S3\tK02982 RP-S3; small subunit ribosomal protein S3" }, { "name":"NITINOP_1758 rpsD; 30S ribosomal subunit protein S4\tK02986 RP-S4; small subunit ribosomal protein S4" }, { "name":"NITINOP_1748 rpsE; 30S ribosomal subunit protein S5\tK02988 RP-S5; small subunit ribosomal protein S5" }, { "name":"NITINOP_0266 rpsF; 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6" }, { "name":"NITINOP_1725 rpsG; 30S ribosomal subunit protein S7\tK02992 RP-S7; small subunit ribosomal protein S7" }, { "name":"NITINOP_1745 rpsH; 30S ribosomal subunit protein S8\tK02994 RP-S8; small subunit ribosomal protein S8" }, { "name":"NITINOP_2468 rpsI; 30S ribosomal subunit protein S9\tK02996 RP-S9; small subunit ribosomal protein S9" }, { "name":"NITINOP_1728 rpsJ; 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10" }, { "name":"NITINOP_1756 rpsK; 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11" }, { "name":"NITINOP_1724 rpsL; 30S ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12" }, { "name":"NITINOP_1755 rpsM; 30S ribosomal subunit protein S13\tK02952 RP-S13; small subunit ribosomal protein S13" }, { "name":"NITINOP_1743 rpsZ; 30S ribosomal protein S14 type Z\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"NITINOP_2333 rpsN; 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"NITINOP_0782 rpsO; 30S ribosomal subunit protein S15\tK02956 RP-S15; small subunit ribosomal protein S15" }, { "name":"NITINOP_3256 rpsP; 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16" }, { "name":"NITINOP_1739 rpsQ; 30S ribosomal subunit protein S17\tK02961 RP-S17; small subunit ribosomal protein S17" }, { "name":"NITINOP_0264 rpsR; 30S ribosomal subunit protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"NITINOP_2332 rpsR; 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"NITINOP_1733 rpsS; 30S ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19" }, { "name":"NITINOP_1416 rpsT; 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20" }, { "name":"NITINOP_1641 rpsU; 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21" }, { "name":"NITINOP_1720 rplA; 50S ribosomal subunit protein L1\tK02863 RP-L1; large subunit ribosomal protein L1" }, { "name":"NITINOP_1732 rplB; 50S ribosomal subunit protein L2\tK02886 RP-L2; large subunit ribosomal protein L2" }, { "name":"NITINOP_1729 rplC; 50S ribosomal subunit protein L3\tK02906 RP-L3; large subunit ribosomal protein L3" }, { "name":"NITINOP_1730 rplD; 50S ribosomal subunit protein L4\tK02926 RP-L4; large subunit ribosomal protein L4" }, { "name":"NITINOP_1742 rplE; 50S ribosomal subunit protein L5\tK02931 RP-L5; large subunit ribosomal protein L5" }, { "name":"NITINOP_1746 rplF; 50S ribosomal subunit protein L6\tK02933 RP-L6; large subunit ribosomal protein L6" }, { "name":"NITINOP_1660 rplI; 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9" }, { "name":"NITINOP_1719 rplK; 50S ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11" }, { "name":"NITINOP_1721 rplJL; Fused 50S ribosomal proteins L10 and L7\/L12 (Modular protein)\tK02935 RP-L7; large subunit ribosomal protein L7\/L12" }, { "name":"NITINOP_2469 rplM; 50S ribosomal subunit protein L13\tK02871 RP-L13; large subunit ribosomal protein L13" }, { "name":"NITINOP_1740 rplN; 50S ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14" }, { "name":"NITINOP_1750 rplO; 50S ribosomal subunit protein L15\tK02876 RP-L15; large subunit ribosomal protein L15" }, { "name":"NITINOP_1736 rplP; 50S ribosomal subunit protein L16\tK02878 RP-L16; large subunit ribosomal protein L16" }, { "name":"NITINOP_1760 rplQ; 50S ribosomal subunit protein L17\tK02879 RP-L17; large subunit ribosomal protein L17" }, { "name":"NITINOP_1747 rplR; 50S ribosomal subunit protein L18\tK02881 RP-L18; large subunit ribosomal protein L18" }, { "name":"NITINOP_3253 rplS; 50S ribosomal subunit protein L19\tK02884 RP-L19; large subunit ribosomal protein L19" }, { "name":"NITINOP_1266 rplT; 50S ribosomal subunit protein L20\tK02887 RP-L20; large subunit ribosomal protein L20" }, { "name":"NITINOP_3164 rplU; 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21" }, { "name":"NITINOP_1734 rplV; 50S ribosomal subunit protein L22\tK02890 RP-L22; large subunit ribosomal protein L22" }, { "name":"NITINOP_1731 rplW; 50S ribosomal subunit protein L23\tK02892 RP-L23; large subunit ribosomal protein L23" }, { "name":"NITINOP_1741 rplX; 50S ribosomal subunit protein L24\tK02895 RP-L24; large subunit ribosomal protein L24" }, { "name":"NITINOP_0275 rplY; 50S ribosomal protein L25\tK02897 RP-L25; large subunit ribosomal protein L25" }, { "name":"NITINOP_3165 rpmA; 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27" }, { "name":"NITINOP_2336 rpmB; 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"NITINOP_2544 rpmB; 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"NITINOP_1737 rpmC; 50S ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29" }, { "name":"NITINOP_1749 rpmD; 50S ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30" }, { "name":"NITINOP_0126 rpmE; 50S ribosomal subunit protein L31\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"NITINOP_2334 rpmE; 50S ribosomal protein L31 type B\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"NITINOP_0262 rpmF; 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32" }, { "name":"NITINOP_1716 rpmG; 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"NITINOP_2337 rpmG; 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"NITINOP_1267 rpmI; 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35" } ] }, { "name":"00970 Aminoacyl-tRNA biosynthesis [PATH:nio00970]", "children":[ { "name":"NITINOP_tRNA20 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"NITINOP_tRNA32 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"NITINOP_tRNA5 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"NITINOP_tRNA1 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA11 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA31 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA35 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA43 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA38 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn" }, { "name":"NITINOP_tRNA22 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp" }, { "name":"NITINOP_tRNA13 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys" }, { "name":"NITINOP_tRNA45 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"NITINOP_tRNA46 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"NITINOP_tRNA3 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"NITINOP_tRNA47 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"NITINOP_tRNA16 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"NITINOP_tRNA25 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"NITINOP_tRNA4 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"NITINOP_tRNA12 tRNA-His\tK14226 tRNA-His; tRNA His" }, { "name":"NITINOP_tRNA19 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"NITINOP_tRNA23 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA24 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA6 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA8 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA9 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA42 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"NITINOP_tRNA44 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"NITINOP_tRNA27 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA40 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA48 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA30 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe" }, { "name":"NITINOP_tRNA10 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"NITINOP_tRNA33 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"NITINOP_tRNA34 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"NITINOP_tRNA26 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA28 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA29 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA41 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA14 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"NITINOP_tRNA17 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"NITINOP_tRNA37 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"NITINOP_tRNA18 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp" }, { "name":"NITINOP_tRNA15 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr" }, { "name":"NITINOP_tRNA21 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"NITINOP_tRNA39 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"NITINOP_tRNA7 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"NITINOP_0506 gltX; Glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"NITINOP_2370 gatA; Glutamyl-tRNA(Gln) amidotransferase subunit A\tK02433 gatA; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]" }, { "name":"NITINOP_2373 gatB; Aspartyl\/glutamyl-tRNA(Asn\/Gln) amidotransferase subunit B\tK02434 gatB; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]" }, { "name":"NITINOP_2368 gatC; Aspartyl\/glutamyl-tRNA(Asn\/Gln) amidotransferase subunit C\tK02435 gatC; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]" }, { "name":"NITINOP_0504 glnS; glutamyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"NITINOP_2529 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"NITINOP_1830 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"NITINOP_2178 glyQ; glycyl-tRNA synthetase, alpha chain\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"NITINOP_2179 glyS; Glycine--tRNA ligase beta subunit\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"NITINOP_1269 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"NITINOP_2833 serS; Serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"NITINOP_1142 cysS; Cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"NITINOP_2362 metG; Methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"NITINOP_1260 fmt; 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase\tK00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]" }, { "name":"NITINOP_2728 valS; Valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"NITINOP_1413 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"NITINOP_1925 ileS; isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"NITINOP_2074 lysU; lysine tRNA synthetase, inducible\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"NITINOP_3332 argS; Arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"NITINOP_1980 proS; prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"NITINOP_0996 hisS; Histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"NITINOP_1263 pheS; Phenylalanine--tRNA ligase alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"NITINOP_1264 pheT; Phenylalanyl-tRNA synthetase, beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"NITINOP_2495 tyrS; Tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"NITINOP_1940 trpS; Tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" } ] }, { "name":"03013 Nucleocytoplasmic transport" }, { "name":"03015 mRNA surveillance pathway" }, { "name":"03008 Ribosome biogenesis in eukaryotes", "children":[ { "name":"NITINOP_0255 rnc; Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" } ] } ] }, { "name":"09123 Folding, sorting and degradation", "children":[ { "name":"03060 Protein export [PATH:nio03060]", "children":[ { "name":"NITINOP_1751 secY; preprotein translocase membrane subunit\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"NITINOP_1717 secE; Protein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"NITINOP_3160 secG; Preprotein translocase, membrane subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"NITINOP_3329 secD; Protein translocase subunit SecD\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"NITINOP_3328 secF; Protein translocase subunit SecF\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"NITINOP_3330 conserved protein of unknown function\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"NITINOP_0905 yidC; Membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"NITINOP_0474 secA; preprotein translocase subunit, ATPase\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"NITINOP_3257 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"NITINOP_misc_RNA8 SRP_bact\tK01983 ffs; signal recognition particle 4.5S RNA" }, { "name":"NITINOP_1161 ftsY; Signal recognition particle receptor FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"NITINOP_0895 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_0896 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_3299 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_1963 tatC; Sec-independent protein translocase protein TatC\tK03118 tatC; sec-independent protein translocase protein TatC" }, { "name":"NITINOP_2797 tatC; Sec-independent protein translocase protein TatC\tK03118 tatC; sec-independent protein translocase protein TatC" }, { "name":"NITINOP_2872 lepB; Signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]" }, { "name":"NITINOP_1926 lspA; Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]" } ] }, { "name":"04141 Protein processing in endoplasmic reticulum", "children":[ { "name":"NITINOP_0036 putative Heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_0311 Heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_0609 Heat shock protein, Hsp20 family\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_0928 Heat shock protein, Hsp20 family\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_2324 Heat shock protein, Hsp20 family\tK13993 HSP20; HSP20 family protein" } ] }, { "name":"04130 SNARE interactions in vesicular transport" }, { "name":"04120 Ubiquitin mediated proteolysis" }, { "name":"04122 Sulfur relay system [PATH:nio04122]", "children":[ { "name":"NITINOP_0510 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"NITINOP_3274 putative 3-mercaptopyruvate sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]" }, { "name":"NITINOP_0897 mnmA; tRNA-specific 2-thiouridylase MnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"NITINOP_2822 moaA; Cyclic pyranopterin monophosphate synthase 3\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]" }, { "name":"NITINOP_3044 conserved protein of unknown function\tK03636 moaD; sulfur-carrier protein" }, { "name":"NITINOP_2823 Molybdopterin synthase catalytic subunit (modular protein)\tK21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12]" }, { "name":"NITINOP_3042 moeB; putative adenylyltransferase HVO_0558\tK21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]" }, { "name":"NITINOP_3046 moeB; molybdopterin synthase sulfurylase\tK21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]" }, { "name":"NITINOP_2824 moaC; molybdopterin biosynthesis, protein C\tK03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]" }, { "name":"NITINOP_2903 moaB; Molybdenum cofactor biosynthesis protein B\tK03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]" }, { "name":"NITINOP_2716 thiI; putative tRNA sulfurtransferase\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]" }, { "name":"NITINOP_0009 putative Thiamine biosynthesis protein ThiS\tK03154 thiS; sulfur carrier protein" }, { "name":"NITINOP_3040 putative Thiamine biosynthesis protein ThiS\tK03154 thiS; sulfur carrier protein" }, { "name":"NITINOP_3244 Thiamine biosynthesis protein ThiS (modular protein)\tK03154 thiS; sulfur carrier protein" } ] }, { "name":"03050 Proteasome [PATH:nio03050]", "children":[ { "name":"NITINOP_1616 Uncharacterized ATPase, AAA family\tK13527 mpa; proteasome-associated ATPase" }, { "name":"NITINOP_3241 arc; Proteasome-associated ATPase\tK13527 mpa; proteasome-associated ATPase" }, { "name":"NITINOP_1620 putative Proteasome, alpha subunit\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]" }, { "name":"NITINOP_3238 prcA; Proteasome subunit alpha\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]" }, { "name":"NITINOP_1619 putative Proteasome, beta subunit\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]" }, { "name":"NITINOP_3239 prcB; Proteasome subunit beta\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]" } ] }, { "name":"03018 RNA degradation [PATH:nio03018]", "children":[ { "name":"NITINOP_2374 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"NITINOP_0781 pnp; polynucleotide phosphorylase\/polyadenylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"NITINOP_0920 deaD; ATP-dependent RNA helicase DeaD\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]" }, { "name":"NITINOP_0127 rho; transcription termination factor\tK03628 rho; transcription termination factor Rho" }, { "name":"NITINOP_1399 rny; Ribonuclease Y\tK18682 rny; ribonucrease Y [EC:3.1.-.-]" }, { "name":"NITINOP_0514 dnaK; chaperone Hsp70, co-chaperone with DnaJ\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_2540 dnaK; chaperone Hsp70 in DNA biosynthesis\/cell division\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_1790 groEL; chaperone Hsp60, peptide-dependent ATPase, heat shock protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"NITINOP_0636 putative Polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" } ] } ] }, { "name":"09124 Replication and repair", "children":[ { "name":"03030 DNA replication [PATH:nio03030]", "children":[ { "name":"NITINOP_2678 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"NITINOP_1079 dnaX; DNA polymerase III, gamma and tau subunits\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"NITINOP_2363 holB; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"NITINOP_1415 holA; putative DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"NITINOP_0992 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"NITINOP_2645 dnaC; Replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]" }, { "name":"NITINOP_0111 dnaG; DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]" }, { "name":"NITINOP_0265 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"NITINOP_3252 rnhB; Ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]" }, { "name":"NITINOP_0108 rnhC; Ribonuclease\tK03471 rnhC; ribonuclease HIII [EC:3.1.26.4]" }, { "name":"NITINOP_1635 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"NITINOP_2058 ligA; DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03410 Base excision repair [PATH:nio03410]", "children":[ { "name":"NITINOP_1639 nth; Endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"NITINOP_2786 nth; Endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"NITINOP_2029 mutY; Endonuclease III\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"NITINOP_0354 putative 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]" }, { "name":"NITINOP_0231 mutM; DNA-formamidopyrimidine glycosylase and DNA-(Apurinic or apyrimidinic site) lyase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"NITINOP_0162 alkA; DNA-3-methyladenine glycosylase\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"NITINOP_1239 conserved protein of unknown function\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"NITINOP_1989 udgA; Uracil-DNA glycosylase\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"NITINOP_1431 xthA; Exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"NITINOP_1635 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"NITINOP_3288 recJ; Single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"NITINOP_2058 ligA; DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03420 Nucleotide excision repair [PATH:nio03420]", "children":[ { "name":"NITINOP_1469 mfd; Transcription-repair-coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"NITINOP_1347 uvrA; Excinuclease ABC, subunit A\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"NITINOP_3268 uvrA; UvrABC system protein A\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"NITINOP_3259 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component\tK03702 uvrB; excinuclease ABC subunit B" }, { "name":"NITINOP_1361 uvrC; UvrABC system protein C\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"NITINOP_1711 ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"NITINOP_1635 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"NITINOP_2058 ligA; DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03430 Mismatch repair [PATH:nio03430]", "children":[ { "name":"NITINOP_0777 mutS; DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS" }, { "name":"NITINOP_3156 mutS; Endonuclease MutS2\tK07456 mutS2; DNA mismatch repair protein MutS2" }, { "name":"NITINOP_1951 mutL; DNA mismatch repair protein MutL\tK03572 mutL; DNA mismatch repair protein MutL" }, { "name":"NITINOP_1711 ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"NITINOP_1401 xseA; Exodeoxyribonuclease 7 large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]" }, { "name":"NITINOP_1402 xseB; Exodeoxyribonuclease 7 small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]" }, { "name":"NITINOP_3288 recJ; Single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"NITINOP_0265 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"NITINOP_2678 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"NITINOP_0992 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"NITINOP_1079 dnaX; DNA polymerase III, gamma and tau subunits\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"NITINOP_1415 holA; putative DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"NITINOP_2363 holB; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"NITINOP_2058 ligA; DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03440 Homologous recombination [PATH:nio03440]", "children":[ { "name":"NITINOP_3288 recJ; Single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"NITINOP_0265 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"NITINOP_2378 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)" }, { "name":"NITINOP_1077 recR; gap repair protein\tK06187 recR; recombination protein RecR" }, { "name":"NITINOP_2527 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA" }, { "name":"NITINOP_1635 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"NITINOP_1282 ruvA; Holliday junction ATP-dependent DNA helicase RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA" }, { "name":"NITINOP_1284 ruvB; ATP-dependent DNA helicase, component of RuvABC resolvasome\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]" }, { "name":"NITINOP_1814 recG; ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"NITINOP_2678 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"NITINOP_0992 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"NITINOP_1079 dnaX; DNA polymerase III, gamma and tau subunits\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"NITINOP_1415 holA; putative DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"NITINOP_2363 holB; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"NITINOP_1104 putative Primosomal protein N\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]" } ] }, { "name":"03450 Non-homologous end-joining" }, { "name":"03460 Fanconi anemia pathway" } ] }, { "name":"09126 Chromosome", "children":[ { "name":"03082 ATP-dependent chromatin remodeling" }, { "name":"03083 Polycomb repressive complex" } ] }, { "name":"09125 Information processing in viruses", "children":[ { "name":"03230 Viral genome structure" }, { "name":"03240 Viral replication" }, { "name":"03250 Viral life cycle - HIV-1" }, { "name":"03260 Virion - Human immunodeficiency virus" }, { "name":"03271 Virion - Rotavirus" }, { "name":"03262 Virion - Coronavirus" }, { "name":"03261 Virion - Influenza virus" }, { "name":"03263 Virion - Enterovirus" }, { "name":"03264 Virion - Flavivirus and Alphavirus" }, { "name":"03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus" }, { "name":"03273 Virion - Lassa virus and SFTS virus" }, { "name":"03272 Virion - Hepatitis viruses" }, { "name":"03266 Virion - Herpesvirus" }, { "name":"03268 Virion - Orthopoxvirus" }, { "name":"03267 Virion - Adenovirus" }, { "name":"03259 Virion - Bacteriophages T4 and T7" }, { "name":"03258 Virion - Bacteriophage lambda" } ] } ] }, { "name":"09130 Environmental Information Processing", "children":[ { "name":"09131 Membrane transport", "children":[ { "name":"02010 ABC transporters [PATH:nio02010]", "children":[ { "name":"NITINOP_3184 modA; Molybdate ABC transporter, periplasmic binding protein\tK02020 modA; molybdate transport system substrate-binding protein" }, { "name":"NITINOP_3185 modB; Molybdate ABC transporter, permease protein\tK02018 modB; molybdate transport system permease protein" }, { "name":"NITINOP_3186 modC; Molybdate ABC transporter, ATP-binding protein\tK02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]" }, { "name":"NITINOP_1890 fbpA; ABC transporter, periplasmic binding component, Fe3+ transport system\tK02012 afuA; iron(III) transport system substrate-binding protein" }, { "name":"NITINOP_1889 fbpB; ABC transporter, permease component, Fe3+ transport system\tK02011 afuB; iron(III) transport system permease protein" }, { "name":"NITINOP_1888 fbpC; ABC transporter, ATP-binding component, Fe3+ transport system\tK02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]" }, { "name":"NITINOP_2738 putative ABC-type sugar transport system, ATPase component\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]" }, { "name":"NITINOP_2741 putative ABC-type sugar transport system, periplasmic binding component\tK10236 thuE; trehalose\/maltose transport system substrate-binding protein" }, { "name":"NITINOP_2740 putative ABC-type sugar transport system, permease component\tK10237 thuF; trehalose\/maltose transport system permease protein" }, { "name":"NITINOP_2739 putative ABC-type sugar transport system, permease component\tK10238 thuG; trehalose\/maltose transport system permease protein" }, { "name":"NITINOP_1574 putative ABC transporter, auxiliary component, ATP-dependent toluene efflux transporter\tK07323 mlaC; phospholipid transport system substrate-binding protein" }, { "name":"NITINOP_0652 putative ABC-type transport system, periplasmic binding component\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"NITINOP_1573 yrbD; putative ABC transporter, periplasmic binding component, ATP-dependent toluene efflux transporter\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"NITINOP_0655 putative ABC-type transport system, permease component\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"NITINOP_1571 yrbE; toluene transporter subunit: membrane component of ABC superfamily\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"NITINOP_0654 putative ABC-type transport system, ATP binding component\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"NITINOP_1572 yrbF; putative ABC transporter, ATPase component, ATP-dependent toluene efflux transporter\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"NITINOP_1321 putative Phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1322 putative Phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1686 PstS; Strongly similar to phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_2211 putative Phosphate-binding protein PstS\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1323 putative Phosphate ABC transporter, permease component\tK02037 pstC; phosphate transport system permease protein" }, { "name":"NITINOP_1324 putative Phosphate ABC transporter, permease component 2\tK02038 pstA; phosphate transport system permease protein" }, { "name":"NITINOP_1325 pstB; Phosphate ABC transporter, ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]" }, { "name":"NITINOP_3362 urtA; Urea ABC transporter, urea binding protein UrtA\tK11959 urtA; urea transport system substrate-binding protein" }, { "name":"NITINOP_3361 urtB; Urea ABC transporter, permease protein UrtB\tK11960 urtB; urea transport system permease protein" }, { "name":"NITINOP_3360 urtC; Urea ABC transporter, permease protein UrtC\tK11961 urtC; urea transport system permease protein" }, { "name":"NITINOP_3359 urtD; Urea ABC transporter, ATP-binding protein UrtD\tK11962 urtD; urea transport system ATP-binding protein" }, { "name":"NITINOP_3358 urtE; Urea ABC transporter, ATP-binding protein UrtE\tK11963 urtE; urea transport system ATP-binding protein" }, { "name":"NITINOP_2073 lolC; Lipoprotein-releasing system, transmembrane protein LolC\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"NITINOP_2072 lolD; outer membrane-specific lipoprotein transporter subunit; ATP-binding component of ABC superfamily\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]" }, { "name":"NITINOP_0072 putative Heme exporter protein CcmD\tK02196 ccmD; heme exporter protein D" }, { "name":"NITINOP_0073 ccmC; Heme exporter protein CcmC\tK02195 ccmC; heme exporter protein C" }, { "name":"NITINOP_0074 ccmB; Heme exporter protein CcmB\tK02194 ccmB; heme exporter protein B" }, { "name":"NITINOP_0075 ccmA; Heme exporter protein CcmA\tK02193 ccmA; heme exporter protein A [EC:7.6.2.5]" }, { "name":"NITINOP_2568 putative Permease, YjgP\/YjgQ family\tK07091 lptF; lipopolysaccharide export system permease protein" }, { "name":"NITINOP_2567 putative Permease, YjgP\/YjgQ family\tK11720 lptG; lipopolysaccharide export system permease protein" }, { "name":"NITINOP_1764 lptB; putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]" }, { "name":"NITINOP_3249 Cell division protein FtsX\tK09811 ftsX; cell division transport system permease protein" }, { "name":"NITINOP_3250 ftsE; transporter subunit: ATP-binding component of ABC superfamily\tK09812 ftsE; cell division transport system ATP-binding protein" }, { "name":"NITINOP_0476 msbA; Lipid A export ATP-binding\/permease protein MsbA\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"NITINOP_3129 msbA; Lipid A export ATP-binding\/permease protein MsbA\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"NITINOP_3206 apxIB; Toxin RTX-I translocation ATP-binding protein\tK11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB\/CyaB" } ] }, { "name":"02060 Phosphotransferase system (PTS)" }, { "name":"03070 Bacterial secretion system [PATH:nio03070]", "children":[ { "name":"NITINOP_0013 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0713 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3265 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3205 putative Type I secretion membrane fusion protein HlyD\tK11003 hlyD; membrane fusion protein, hemolysin D" }, { "name":"NITINOP_3206 apxIB; Toxin RTX-I translocation ATP-binding protein\tK11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB\/CyaB" }, { "name":"NITINOP_0218 putative general secretion pathway protein D\tK02453 gspD; general secretion pathway protein D" }, { "name":"NITINOP_1675 exported protein of unknown function\tK02452 gspC; general secretion pathway protein C" }, { "name":"NITINOP_2307 protein of unknown function\tK02452 gspC; general secretion pathway protein C" }, { "name":"NITINOP_2305 gspF; General secretion pathway protein F\tK02455 gspF; general secretion pathway protein F" }, { "name":"NITINOP_2304 gspG; pseudopilin, cryptic, general secretion pathway\tK02456 gspG; general secretion pathway protein G" }, { "name":"NITINOP_2303 exported protein of unknown function\tK02457 gspH; general secretion pathway protein H" }, { "name":"NITINOP_2302 putative general secretion pathway protein I\tK02458 gspI; general secretion pathway protein I" }, { "name":"NITINOP_2301 protein of unknown function\tK02459 gspJ; general secretion pathway protein J" }, { "name":"NITINOP_2297 putative general secretion pathway protein K\tK02460 gspK; general secretion pathway protein K" }, { "name":"NITINOP_2299 protein of unknown function\tK02461 gspL; general secretion pathway protein L" }, { "name":"NITINOP_2298 protein of unknown function\tK02462 gspM; general secretion pathway protein M" }, { "name":"NITINOP_2306 gspE; general secretory pathway component, cryptic\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"NITINOP_3329 secD; Protein translocase subunit SecD\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"NITINOP_3328 secF; Protein translocase subunit SecF\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"NITINOP_1717 secE; Protein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"NITINOP_3160 secG; Preprotein translocase, membrane subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"NITINOP_1751 secY; preprotein translocase membrane subunit\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"NITINOP_3330 conserved protein of unknown function\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"NITINOP_0905 yidC; Membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"NITINOP_0474 secA; preprotein translocase subunit, ATPase\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"NITINOP_1161 ftsY; Signal recognition particle receptor FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"NITINOP_3257 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"NITINOP_0895 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_0896 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_3299 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_1963 tatC; Sec-independent protein translocase protein TatC\tK03118 tatC; sec-independent protein translocase protein TatC" }, { "name":"NITINOP_2797 tatC; Sec-independent protein translocase protein TatC\tK03118 tatC; sec-independent protein translocase protein TatC" }, { "name":"NITINOP_2978 conserved protein of unknown function\tK03197 virB2; type IV secretion system protein VirB2" }, { "name":"NITINOP_2979 virB; Type IV secretion system protein virB3\tK03198 virB3; type IV secretion system protein VirB3" }, { "name":"NITINOP_2982 P-type DNA transfer protein VirB5\tK03200 virB5; type IV secretion system protein VirB5" }, { "name":"NITINOP_2985 conserved exported protein of unknown function\tK03204 virB9; type IV secretion system protein VirB9" }, { "name":"NITINOP_2981 conserved membrane protein of unknown function\tK03201 virB6; type IV secretion system protein VirB6" }, { "name":"NITINOP_2983 conserved protein of unknown function\tK03203 virB8; type IV secretion system protein VirB8" }, { "name":"NITINOP_2986 conserved protein of unknown function\tK03195 virB10; type IV secretion system protein VirB10" }, { "name":"NITINOP_2980 virB; Type IV secretion system protein virB4\tK03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]" }, { "name":"NITINOP_2987 virB; Type IV secretion system protein VirB11\tK03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]" }, { "name":"NITINOP_2988 conserved exported protein of unknown function\tK03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]" }, { "name":"NITINOP_1442 Type VI secretion system effector, Hcp1 family\tK11903 hcp; type VI secretion system secreted protein Hcp" } ] } ] }, { "name":"09132 Signal transduction", "children":[ { "name":"02020 Two-component system [PATH:nio02020]", "children":[ { "name":"NITINOP_1564 putative Phosphate regulon sensor histidine kinase PhoR\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]" }, { "name":"NITINOP_1565 phoB; DNA-binding response regulator in two-component regulatory system with PhoR (or CreC)\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP" }, { "name":"NITINOP_1672 phoP; Alkaline phosphatase synthesis transcriptional regulatory protein PhoP\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP" }, { "name":"NITINOP_1902 Phosphodiesterase\/alkaline phosphatase D\tK01113 phoD; alkaline phosphatase D [EC:3.1.3.1]" }, { "name":"NITINOP_1687 putative Phosphate regulon transcriptional regulatory protein PhoB\tK07776 regX3; two-component system, OmpR family, response regulator RegX3" }, { "name":"NITINOP_1321 putative Phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1322 putative Phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1686 PstS; Strongly similar to phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_2211 putative Phosphate-binding protein PstS\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_0368 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1009 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1962 degP; Protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_2660 putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_3076 degQ; Protease DegQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_0373 putative Similar to heavy metal efflux pump protein CzcC\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"NITINOP_2958 conserved exported protein of unknown function\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"NITINOP_2971 putative Similar to heavy metal efflux pump protein CzcC\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"NITINOP_0372 Efflux transporter, RND family, MFP subunit (modular protein)\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"NITINOP_2957 conserved exported protein of unknown function\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"NITINOP_2970 protein of unknown function\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"NITINOP_0371 cusA; copper\/silver efflux system, membrane component\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"NITINOP_2956 cusA; copper\/silver efflux system, membrane component\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"NITINOP_2969 cusA; copper\/silver efflux system, membrane component\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"NITINOP_2268 hag; Flagellin\tK02406 fliC; flagellin" }, { "name":"NITINOP_2148 fliA; RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" }, { "name":"NITINOP_2279 motA; Flagellar motor protein MotA\tK02556 motA; chemotaxis protein MotA" }, { "name":"NITINOP_1506 kdpD; fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein; sensory histidine kinase\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]" }, { "name":"NITINOP_1507 kdpE; DNA-binding response regulator in two-component regulatory system with KdpD\tK07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE" }, { "name":"NITINOP_1503 kdpA; Potassium translocating ATPase, subunit A\tK01546 kdpA; potassium-transporting ATPase potassium-binding subunit" }, { "name":"NITINOP_1504 kdpB; Potassium translocating ATPase, subunit B\tK01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]" }, { "name":"NITINOP_1505 kdpC; Potassium translocating ATPase, subunit C\tK01548 kdpC; potassium-transporting ATPase KdpC subunit" }, { "name":"NITINOP_0993 dnaA; chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"NITINOP_0020 Response regulator, CheY like\tK02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F" }, { "name":"NITINOP_1541 spo0F; Sporulation initiation phosphotransferase F\tK02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F" }, { "name":"NITINOP_2316 maeB; Malate dehydrogenase (oxaloacetate-decarboxylating)\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]" }, { "name":"NITINOP_0879 nxrA; Nitrite oxidoreductase, alpha subunit\tK00370 narG; nitrate reductase \/ nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]" }, { "name":"NITINOP_0878 nxrB; Nitrate oxidoreductase, beta subunit\tK00371 narH; nitrate reductase \/ nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]" }, { "name":"NITINOP_2159 csrA; Carbon storage regulator homolog\tK03563 csrA; carbon storage regulator" }, { "name":"NITINOP_1100 devR; Transcriptional regulatory protein DevR (DosR)\tK07695 devR; two-component system, NarL family, response regulator DevR" }, { "name":"NITINOP_1356 putative NarL family two-component system response regulator\tK07695 devR; two-component system, NarL family, response regulator DevR" }, { "name":"NITINOP_0822 protein of unknown function\tK02651 flp; pilus assembly protein Flp\/PilA" }, { "name":"NITINOP_2342 conserved protein of unknown function\tK02651 flp; pilus assembly protein Flp\/PilA" }, { "name":"NITINOP_0823 exported protein of unknown function\tK02279 cpaB; pilus assembly protein CpaB" }, { "name":"NITINOP_0824 putative Pilus assembly protein CpaC\tK02280 cpaC; pilus assembly protein CpaC" }, { "name":"NITINOP_2348 Response regulator receiver protein\tK02282 cpaE; pilus assembly protein CpaE" }, { "name":"NITINOP_0829 cpaF; Pilus assembly ATPase CpaF\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]" }, { "name":"NITINOP_2349 Type II secretion system protein E\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]" }, { "name":"NITINOP_0830 membrane protein of unknown function\tK12510 tadB; tight adherence protein B" }, { "name":"NITINOP_2350 putative Type II secretion system protein\tK12510 tadB; tight adherence protein B" }, { "name":"NITINOP_0831 putative Pilus assembly protein TadC\tK12511 tadC; tight adherence protein C" }, { "name":"NITINOP_2351 Type II secretion system protein\tK12511 tadC; tight adherence protein C" }, { "name":"NITINOP_1270 conserved protein of unknown function\tK07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG" }, { "name":"NITINOP_1778 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"NITINOP_2230 Sensor histidine kinase\tK13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]" }, { "name":"NITINOP_2231 ntrX; Nitrogen assimilation regulatory protein NtrX\tK13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX" }, { "name":"NITINOP_0732 Sensory sigma-54 dependent transcriptional regulator\tK07713 zraR; two-component system, NtrC family, response regulator HydG" }, { "name":"NITINOP_3149 zraR; Transcriptional regulatory protein ZraR\tK07713 zraR; two-component system, NtrC family, response regulator HydG" }, { "name":"NITINOP_1479 Sigma-54 dependent transcriptional regulator\tK07714 atoC; two-component system, NtrC family, response regulator AtoC" }, { "name":"NITINOP_2814 atoC; Acetoacetate metabolism regulatory protein AtoC\tK07714 atoC; two-component system, NtrC family, response regulator AtoC" }, { "name":"NITINOP_3326 atoC; Acetoacetate metabolism regulatory protein AtoC\tK07714 atoC; two-component system, NtrC family, response regulator AtoC" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_0280 putative Sensor protein PilS\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"NITINOP_0279 atoC; fused response regulator of ato opeon, in two-component system with AtoS: response regulator; sigma54 interaction protein\tK02667 pilR; two-component system, NtrC family, response regulator PilR" }, { "name":"NITINOP_1765 rpoN; RNA polymerase, sigma-54 (Sigma N) factor\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"NITINOP_2648 putative Type IV pilin PilA\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"NITINOP_2114 putative Sensor histidine kinase\tK07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]" }, { "name":"NITINOP_2116 yfhA; putative DNA-binding response regulator in two-component system\tK07715 glrR; two-component system, NtrC family, response regulator GlrR" }, { "name":"NITINOP_2290 cheR; chemotaxis regulator, protein-glutamate methyltransferase\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]" }, { "name":"NITINOP_2287 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_2288 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_3387 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_2286 cheW; purine-binding chemotaxis protein\tK03408 cheW; purine-binding chemotaxis protein CheW" }, { "name":"NITINOP_2558 protein of unknown function\tK03408 cheW; purine-binding chemotaxis protein CheW" }, { "name":"NITINOP_2284 cheA; fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase; signal sensing protein\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]" }, { "name":"NITINOP_1102 Signal transduction response regulator, receiver domain\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2277 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2283 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2292 cheB; fused chemotaxis regulator; protein-glutamate methylesterase in two-component regulatory system with CheA\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]" }, { "name":"NITINOP_2559 putative Methyl-accepting chemotaxis protein\tK02660 pilJ; twitching motility protein PilJ" }, { "name":"NITINOP_2560 putative Histidine kinase\tK06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase\/response regulator)" }, { "name":"NITINOP_0183 Putative Hybrid sensor histidine kinase (fragment)\tK13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]" }, { "name":"NITINOP_1121 putative Hybrid histidine kinase\tK13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]" }, { "name":"NITINOP_1972 putative Response Regulator\tK13589 cpdR; two-component system, cell cycle response regulator CpdR" }, { "name":"NITINOP_1697 putative TRAP dicarboxylate transporter-DctP subunit\tK11688 dctP; TRAP-type transport system periplasmic protein" }, { "name":"NITINOP_1698 TRAP dicarboxylate transporter-DctM subunit\tK21393 dctQM; TRAP-type transport system permease protein" }, { "name":"NITINOP_1592 putative Quinol-cytochrome c reductase, cytochrome b subunit\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit" }, { "name":"NITINOP_0673 cydA; Cytochrome bd oxidase, subunit I\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_1589 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_1594 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_3338 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_3345 conserved membrane protein of unknown function, Cytochrome bd-type quinol oxidase subunit 1-like\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"NITINOP_0672 cydB; Cytochrome bd oxidase, subunit II\tK00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]" }, { "name":"NITINOP_0013 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0713 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3265 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0409 exported protein of unknown function\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"NITINOP_2387 Putative Polysaccharide export protein (fragment)\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"NITINOP_2388 putative Polysaccharide export protein\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"NITINOP_2411 putative Protein-tyrosine-phosphatase\tK25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]" }, { "name":"NITINOP_0413 UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]" }, { "name":"NITINOP_2155 flgM; Anti-sigma 28 factor FlgM\tK02398 flgM; negative regulator of flagellin synthesis FlgM" } ] }, { "name":"04010 MAPK signaling pathway" }, { "name":"04013 MAPK signaling pathway - fly" }, { "name":"04016 MAPK signaling pathway - plant" }, { "name":"04011 MAPK signaling pathway - yeast" }, { "name":"04012 ErbB signaling pathway" }, { "name":"04014 Ras signaling pathway" }, { "name":"04015 Rap1 signaling pathway" }, { "name":"04310 Wnt signaling pathway" }, { "name":"04330 Notch signaling pathway" }, { "name":"04340 Hedgehog signaling pathway" }, { "name":"04341 Hedgehog signaling pathway - fly" }, { "name":"04350 TGF-beta signaling pathway" }, { "name":"04390 Hippo signaling pathway" }, { "name":"04391 Hippo signaling pathway - fly" }, { "name":"04392 Hippo signaling pathway - multiple species" }, { "name":"04370 VEGF signaling pathway" }, { "name":"04371 Apelin signaling pathway" }, { "name":"04630 JAK-STAT signaling pathway" }, { "name":"04064 NF-kappa B signaling pathway" }, { "name":"04668 TNF signaling pathway" }, { "name":"04066 HIF-1 signaling pathway" }, { "name":"04068 FoxO signaling pathway" }, { "name":"04020 Calcium signaling pathway" }, { "name":"04070 Phosphatidylinositol signaling system" }, { "name":"04072 Phospholipase D signaling pathway" }, { "name":"04071 Sphingolipid signaling pathway" }, { "name":"04024 cAMP signaling pathway" }, { "name":"04022 cGMP-PKG signaling pathway" }, { "name":"04151 PI3K-Akt signaling pathway" }, { "name":"04152 AMPK signaling pathway" }, { "name":"04150 mTOR signaling pathway" }, { "name":"04075 Plant hormone signal transduction" } ] }, { "name":"09133 Signaling molecules and interaction", "children":[ { "name":"04080 Neuroactive ligand-receptor interaction" }, { "name":"04082 Neuroactive ligand signaling" }, { "name":"04081 Hormone signaling" }, { "name":"04060 Cytokine-cytokine receptor interaction" }, { "name":"04061 Viral protein interaction with cytokine and cytokine receptor" }, { "name":"04512 ECM-receptor interaction" }, { "name":"04514 Cell adhesion molecule (CAM) interaction" }, { "name":"04517 IgSF CAM signaling" }, { "name":"04518 Integrin signaling" }, { "name":"04519 Cadherin signaling" } ] } ] }, { "name":"09140 Cellular Processes", "children":[ { "name":"09141 Transport and catabolism", "children":[ { "name":"04144 Endocytosis" }, { "name":"04145 Phagocytosis" }, { "name":"04142 Lysosome biogenesis" }, { "name":"04146 Peroxisome [PATH:nio04146]", "children":[ { "name":"NITINOP_0743 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0933 putative 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0225 idh; Isocitrate dehydrogenase (NADP(+))\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"NITINOP_0939 mvaB; Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"NITINOP_1434 katA; catalase (hydroperoxidase II)\tK03781 katE; catalase [EC:1.11.1.6]" } ] }, { "name":"04149 Peroxisome - yeast" }, { "name":"04140 Autophagy - animal" }, { "name":"04138 Autophagy - yeast" }, { "name":"04136 Autophagy - other" }, { "name":"04137 Mitophagy - animal" }, { "name":"04139 Mitophagy - yeast" }, { "name":"04148 Efferocytosis" } ] }, { "name":"09143 Cell growth and death", "children":[ { "name":"04110 Cell cycle" }, { "name":"04111 Cell cycle - yeast" }, { "name":"04112 Cell cycle - Caulobacter" }, { "name":"04113 Meiosis - yeast" }, { "name":"04114 Oocyte meiosis" }, { "name":"04210 Apoptosis" }, { "name":"04214 Apoptosis - fly" }, { "name":"04215 Apoptosis - multiple species" }, { "name":"04216 Ferroptosis" }, { "name":"04217 Necroptosis" }, { "name":"04115 p53 signaling pathway" }, { "name":"04218 Cellular senescence" }, { "name":"04156 Integrated stress response (ISR) signaling pathway [PATH:nio04156]", "children":[ { "name":"NITINOP_tRNA27 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA40 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA48 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_0514 dnaK; chaperone Hsp70, co-chaperone with DnaJ\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_2540 dnaK; chaperone Hsp70 in DNA biosynthesis\/cell division\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_1790 groEL; chaperone Hsp60, peptide-dependent ATPase, heat shock protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" } ] } ] }, { "name":"09144 Cellular community - eukaryotes", "children":[ { "name":"04510 Focal adhesion" }, { "name":"04520 Adherens junction" }, { "name":"04530 Tight junction" }, { "name":"04540 Gap junction" }, { "name":"04550 Signaling pathways regulating pluripotency of stem cells" } ] }, { "name":"09145 Cellular community - prokaryotes", "children":[ { "name":"02024 Quorum sensing [PATH:nio02024]", "children":[ { "name":"NITINOP_2060 trpE; Anthranilate synthase component 1\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]" }, { "name":"NITINOP_2061 pabA; aminodeoxychorismate synthase, subunit II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]" }, { "name":"NITINOP_2353 aroF; 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"NITINOP_2909 yddE; Uncharacterized isomerase\tK06998 phzF; trans-2,3-dihydro-3-hydroxyanthranilate isomerase [EC:5.3.3.17]" }, { "name":"NITINOP_2114 putative Sensor histidine kinase\tK07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]" }, { "name":"NITINOP_2116 yfhA; putative DNA-binding response regulator in two-component system\tK07715 glrR; two-component system, NtrC family, response regulator GlrR" }, { "name":"NITINOP_1507 kdpE; DNA-binding response regulator in two-component regulatory system with KdpD\tK07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE" }, { "name":"NITINOP_0743 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0933 putative 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_2181 ribD; Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase]\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]" }, { "name":"NITINOP_0164 oprM; Outer membrane protein OprM\tK18139 oprM; outer membrane protein, multidrug efflux system" }, { "name":"NITINOP_1358 N-acyl-L-homoserine lactone synthase (modular protein)\tK22957 cviI; acyl homoserine lactone synthase [EC:2.3.1.184]" }, { "name":"NITINOP_1359 aubR; Transcriptional regulator\tK20334 cviR; LuxR family transcriptional regulator, quorum-sensing system regulator CviR" }, { "name":"NITINOP_0905 yidC; Membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"NITINOP_1717 secE; Protein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"NITINOP_3160 secG; Preprotein translocase, membrane subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"NITINOP_1751 secY; preprotein translocase membrane subunit\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"NITINOP_3330 conserved protein of unknown function\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"NITINOP_0474 secA; preprotein translocase subunit, ATPase\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"NITINOP_1161 ftsY; Signal recognition particle receptor FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"NITINOP_3257 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"NITINOP_0020 Response regulator, CheY like\tK02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F" }, { "name":"NITINOP_1541 spo0F; Sporulation initiation phosphotransferase F\tK02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F" } ] }, { "name":"05111 Biofilm formation - Vibrio cholerae" }, { "name":"02025 Biofilm formation - Pseudomonas aeruginosa" }, { "name":"02026 Biofilm formation - Escherichia coli" } ] }, { "name":"09142 Cell motility", "children":[ { "name":"02030 Bacterial chemotaxis [PATH:nio02030]", "children":[ { "name":"NITINOP_2287 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_2288 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_3387 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_2284 cheA; fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase; signal sensing protein\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]" }, { "name":"NITINOP_2286 cheW; purine-binding chemotaxis protein\tK03408 cheW; purine-binding chemotaxis protein CheW" }, { "name":"NITINOP_2558 protein of unknown function\tK03408 cheW; purine-binding chemotaxis protein CheW" }, { "name":"NITINOP_1102 Signal transduction response regulator, receiver domain\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2277 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2283 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2278 putative Chemotaxis regulator CheZ\tK03414 cheZ; chemotaxis protein CheZ" }, { "name":"NITINOP_2292 cheB; fused chemotaxis regulator; protein-glutamate methylesterase in two-component regulatory system with CheA\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]" }, { "name":"NITINOP_2291 cheD; putative chemoreceptor glutamine deamidase CheD\tK03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]" }, { "name":"NITINOP_2290 cheR; chemotaxis regulator, protein-glutamate methyltransferase\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]" }, { "name":"NITINOP_2128 fliG; flagellar motor switching and energizing component\tK02410 fliG; flagellar motor switch protein FliG" }, { "name":"NITINOP_2138 fliM; Flagellar motor switch protein FliM\tK02416 fliM; flagellar motor switch protein FliM" }, { "name":"NITINOP_2139 fliN; flagellar motor switching and energizing component\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"NITINOP_2279 motA; Flagellar motor protein MotA\tK02556 motA; chemotaxis protein MotA" }, { "name":"NITINOP_2280 motB; Flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" } ] }, { "name":"02040 Flagellar assembly [PATH:nio02040]", "children":[ { "name":"NITINOP_2126 putative Flagellar hook-basal body complex protein FliE\tK02408 fliE; flagellar hook-basal body complex protein FliE" }, { "name":"NITINOP_2127 fliF; Flagellar M-ring protein\tK02409 fliF; flagellar M-ring protein FliF" }, { "name":"NITINOP_2128 fliG; flagellar motor switching and energizing component\tK02410 fliG; flagellar motor switch protein FliG" }, { "name":"NITINOP_2129 putative Flagellar biosynthesis protein FliH with response regulator receiver domain (Modular protein)\tK02411 fliH; flagellar assembly protein FliH" }, { "name":"NITINOP_2130 fliI; flagellum-specific ATP synthase\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]" }, { "name":"NITINOP_2131 conserved protein of unknown function\tK02413 fliJ; flagellar protein FliJ" }, { "name":"NITINOP_2133 protein of unknown function\tK02414 fliK; flagellar hook-length control protein FliK" }, { "name":"NITINOP_2137 fliL; Flagellar basal body-associated protein FliL\tK02415 fliL; flagellar protein FliL" }, { "name":"NITINOP_2138 fliM; Flagellar motor switch protein FliM\tK02416 fliM; flagellar motor switch protein FliM" }, { "name":"NITINOP_2139 fliN; flagellar motor switching and energizing component\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"NITINOP_2140 putative Flagellar biosynthetic protein FliO, export component\tK02418 fliO; flagellar protein FliO\/FliZ" }, { "name":"NITINOP_2141 fliP; flagellar biosynthesis protein\tK02419 fliP; flagellar biosynthesis protein FliP" }, { "name":"NITINOP_2142 fliQ; flagellar biosynthesis protein\tK02420 fliQ; flagellar biosynthesis protein FliQ" }, { "name":"NITINOP_2143 fliR; Flagellar biosynthetic protein fliR\tK02421 fliR; flagellar biosynthesis protein FliR" }, { "name":"NITINOP_2145 flhA; putative flagellar export pore protein\tK02400 flhA; flagellar biosynthesis protein FlhA" }, { "name":"NITINOP_2144 flhB; Flagellar biosynthetic protein FlhB, export component\tK02401 flhB; flagellar biosynthesis protein FlhB" }, { "name":"NITINOP_2151 putative Flagella basal body P-ring formation protein FlgA\tK02386 flgA; flagellar basal body P-ring formation protein FlgA" }, { "name":"NITINOP_2124 flgB; Flagellar basal body rod protein FlgB\tK02387 flgB; flagellar basal-body rod protein FlgB" }, { "name":"NITINOP_2125 flgC; flagellar component of cell-proximal portion of basal-body rod\tK02388 flgC; flagellar basal-body rod protein FlgC" }, { "name":"NITINOP_2134 putative Flagellar hook capping protein\tK02389 flgD; flagellar basal-body rod modification protein FlgD" }, { "name":"NITINOP_2135 putative Flagellar hook protein FlgE\tK02390 flgE; flagellar hook protein FlgE" }, { "name":"NITINOP_2149 flgF; Flagellar basal-body rod protein FlgF\tK02391 flgF; flagellar basal-body rod protein FlgF" }, { "name":"NITINOP_2150 flgG; flagellar component of cell-distal portion of basal-body rod\tK02392 flgG; flagellar basal-body rod protein FlgG" }, { "name":"NITINOP_2152 flgH; Flagellar L-ring protein\tK02393 flgH; flagellar L-ring protein FlgH" }, { "name":"NITINOP_2153 flgI; Flagellar P-ring protein\tK02394 flgI; flagellar P-ring protein FlgI" }, { "name":"NITINOP_2154 protein of unknown function\tK02395 flgJ; peptidoglycan hydrolase FlgJ" }, { "name":"NITINOP_2157 protein of unknown function\tK02396 flgK; flagellar hook-associated protein 1" }, { "name":"NITINOP_2158 protein of unknown function\tK02397 flgL; flagellar hook-associated protein 3 FlgL" }, { "name":"NITINOP_2268 hag; Flagellin\tK02406 fliC; flagellin" }, { "name":"NITINOP_2270 putative Flagellar capping protein FliD\tK02407 fliD; flagellar hook-associated protein 2" }, { "name":"NITINOP_2271 fliS; Flagellin-specific chaperone FliS\tK02422 fliS; flagellar secretion chaperone FliS" }, { "name":"NITINOP_2279 motA; Flagellar motor protein MotA\tK02556 motA; chemotaxis protein MotA" }, { "name":"NITINOP_2280 motB; Flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" }, { "name":"NITINOP_2155 flgM; Anti-sigma 28 factor FlgM\tK02398 flgM; negative regulator of flagellin synthesis FlgM" }, { "name":"NITINOP_0110 rpoD; RNA polymerase, sigma 70 (sigma D) factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"NITINOP_1305 rpoD; RNA polymerase sigma factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"NITINOP_1765 rpoN; RNA polymerase, sigma-54 (Sigma N) factor\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"NITINOP_2148 fliA; RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" } ] }, { "name":"04814 Motor proteins" }, { "name":"04820 Cytoskeleton in muscle cells [PATH:nio04820]", "children":[ { "name":"NITINOP_0570 putative Calcium-transporting ATPase\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]" }, { "name":"NITINOP_2374 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" } ] }, { "name":"04810 Regulation of actin cytoskeleton" } ] } ] }, { "name":"09150 Organismal Systems", "children":[ { "name":"09151 Immune system", "children":[ { "name":"04640 Hematopoietic cell lineage" }, { "name":"04610 Complement and coagulation cascades" }, { "name":"04611 Platelet activation" }, { "name":"04613 Neutrophil extracellular trap formation" }, { "name":"04620 Toll-like receptor signaling pathway" }, { "name":"04624 Toll and Imd signaling pathway" }, { "name":"04621 NOD-like receptor signaling pathway" }, { "name":"04622 RIG-I-like receptor signaling pathway" }, { "name":"04623 Cytosolic DNA-sensing pathway" }, { "name":"04625 C-type lectin receptor signaling pathway" }, { "name":"04650 Natural killer cell mediated cytotoxicity" }, { "name":"04612 Antigen processing and presentation" }, { "name":"04660 T cell receptor signaling pathway" }, { "name":"04658 Th1 and Th2 cell differentiation" }, { "name":"04659 Th17 cell differentiation" }, { "name":"04657 IL-17 signaling pathway" }, { "name":"04662 B cell receptor signaling pathway" }, { "name":"04664 Fc epsilon RI signaling pathway" }, { "name":"04666 Fc gamma R-mediated phagosome formation" }, { "name":"04670 Leukocyte transendothelial migration" }, { "name":"04672 Intestinal immune network for IgA production" }, { "name":"04062 Chemokine signaling pathway" } ] }, { "name":"09152 Endocrine system", "children":[ { "name":"04911 Insulin secretion" }, { "name":"04910 Insulin signaling pathway" }, { "name":"04922 Glucagon signaling pathway" }, { "name":"04923 Regulation of lipolysis in adipocytes" }, { "name":"04920 Adipocytokine signaling pathway" }, { "name":"03320 PPAR signaling pathway" }, { "name":"04929 GnRH secretion" }, { "name":"04912 GnRH signaling pathway" }, { "name":"04913 Ovarian steroidogenesis" }, { "name":"04915 Estrogen signaling pathway" }, { "name":"04914 Progesterone-mediated oocyte maturation" }, { "name":"04917 Prolactin signaling pathway" }, { "name":"04921 Oxytocin signaling pathway" }, { "name":"04926 Relaxin signaling pathway" }, { "name":"04935 Growth hormone synthesis, secretion and action" }, { "name":"04918 Thyroid hormone synthesis" }, { "name":"04919 Thyroid hormone signaling pathway" }, { "name":"04928 Parathyroid hormone synthesis, secretion and action" }, { "name":"04916 Melanogenesis" }, { "name":"04924 Renin secretion" }, { "name":"04614 Renin-angiotensin system" }, { "name":"04925 Aldosterone synthesis and secretion" }, { "name":"04927 Cortisol synthesis and secretion" } ] }, { "name":"09153 Circulatory system", "children":[ { "name":"04260 Cardiac muscle contraction" }, { "name":"04261 Adrenergic signaling in cardiomyocytes" }, { "name":"04270 Vascular smooth muscle contraction" } ] }, { "name":"09154 Digestive system", "children":[ { "name":"04970 Salivary secretion" }, { "name":"04971 Gastric acid secretion" }, { "name":"04972 Pancreatic secretion" }, { "name":"04976 Bile secretion" }, { "name":"04973 Carbohydrate digestion and absorption" }, { "name":"04974 Protein digestion and absorption" }, { "name":"04975 Fat digestion and absorption" }, { "name":"04979 Cholesterol metabolism" }, { "name":"04977 Vitamin digestion and absorption" }, { "name":"04981 Folate transport and metabolism [PATH:nio04981]", "children":[ { "name":"NITINOP_1661 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"NITINOP_3013 metH; homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" } ] }, { "name":"04980 Cobalamin transport and metabolism [PATH:nio04980]", "children":[ { "name":"NITINOP_2551 yvqK; Cob(I)yrinic acid a,c-diamide adenosyltransferase\tK00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]" }, { "name":"NITINOP_0938 argK; LAO\/AO transport system ATPase\tK07588 MMAA; GTPase [EC:3.6.5.-]" }, { "name":"NITINOP_3013 metH; homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" } ] }, { "name":"04978 Mineral absorption" } ] }, { "name":"09155 Excretory system", "children":[ { "name":"04962 Vasopressin-regulated water reabsorption" }, { "name":"04960 Aldosterone-regulated sodium reabsorption" }, { "name":"04961 Endocrine and other factor-regulated calcium reabsorption" }, { "name":"04964 Proximal tubule bicarbonate reclamation" }, { "name":"04966 Collecting duct acid secretion" } ] }, { "name":"09156 Nervous system", "children":[ { "name":"04724 Glutamatergic synapse" }, { "name":"04727 GABAergic synapse" }, { "name":"04725 Cholinergic synapse" }, { "name":"04728 Dopaminergic synapse" }, { "name":"04726 Serotonergic synapse" }, { "name":"04720 Long-term potentiation" }, { "name":"04730 Long-term depression" }, { "name":"04723 Retrograde endocannabinoid signaling" }, { "name":"04721 Synaptic vesicle cycle" }, { "name":"04722 Neurotrophin signaling pathway" } ] }, { "name":"09157 Sensory system", "children":[ { "name":"04744 Phototransduction" }, { "name":"04745 Phototransduction - fly" }, { "name":"04740 Olfactory transduction" }, { "name":"04742 Taste transduction" }, { "name":"04750 Inflammatory mediator regulation of TRP channels" } ] }, { "name":"09158 Development and regeneration", "children":[ { "name":"04320 Dorso-ventral axis formation" }, { "name":"04360 Axon guidance" }, { "name":"04361 Axon regeneration" }, { "name":"04380 Osteoclast differentiation" }, { "name":"04382 Cornified envelope formation" } ] }, { "name":"09149 Aging", "children":[ { "name":"04211 Longevity regulating pathway" }, { "name":"04212 Longevity regulating pathway - worm" }, { "name":"04213 Longevity regulating pathway - multiple species" } ] }, { "name":"09159 Environmental adaptation", "children":[ { "name":"04710 Circadian rhythm" }, { "name":"04713 Circadian entrainment" }, { "name":"04711 Circadian rhythm - fly" }, { "name":"04712 Circadian rhythm - plant" }, { "name":"04714 Thermogenesis" }, { "name":"04626 Plant-pathogen interaction" } ] } ] }, { "name":"09160 Human Diseases", "children":[ { "name":"09161 Cancer: overview", "children":[ { "name":"05200 Pathways in cancer" }, { "name":"05202 Transcriptional misregulation in cancer" }, { "name":"05206 MicroRNAs in cancer" }, { "name":"05205 Proteoglycans in cancer" }, { "name":"05204 Chemical carcinogenesis - DNA adducts" }, { "name":"05207 Chemical carcinogenesis - receptor activation" }, { "name":"05208 Chemical carcinogenesis - reactive oxygen species" }, { "name":"05203 Viral carcinogenesis" }, { "name":"05230 Central carbon metabolism in cancer" }, { "name":"05231 Choline metabolism in cancer" }, { "name":"05235 PD-L1 expression and PD-1 checkpoint pathway in cancer" } ] }, { "name":"09162 Cancer: specific types", "children":[ { "name":"05210 Colorectal cancer" }, { "name":"05212 Pancreatic cancer" }, { "name":"05225 Hepatocellular carcinoma" }, { "name":"05226 Gastric cancer" }, { "name":"05214 Glioma" }, { "name":"05216 Thyroid cancer" }, { "name":"05221 Acute myeloid leukemia" }, { "name":"05220 Chronic myeloid leukemia" }, { "name":"05217 Basal cell carcinoma" }, { "name":"05218 Melanoma" }, { "name":"05211 Renal cell carcinoma" }, { "name":"05219 Bladder cancer" }, { "name":"05215 Prostate cancer" }, { "name":"05213 Endometrial cancer" }, { "name":"05224 Breast cancer" }, { "name":"05222 Small cell lung cancer" }, { "name":"05223 Non-small cell lung cancer" } ] }, { "name":"09172 Infectious disease: viral", "children":[ { "name":"05166 Human T-cell leukemia virus 1 infection" }, { "name":"05170 Human immunodeficiency virus 1 infection" }, { "name":"05161 Hepatitis B" }, { "name":"05160 Hepatitis C" }, { "name":"05171 Coronavirus disease" }, { "name":"05164 Influenza A" }, { "name":"05162 Measles" }, { "name":"05168 Herpes simplex virus 1 infection" }, { "name":"05163 Human cytomegalovirus infection" }, { "name":"05167 Kaposi sarcoma-associated herpesvirus infection" }, { "name":"05169 Epstein-Barr virus infection" }, { "name":"05165 Human papillomavirus infection" } ] }, { "name":"09171 Infectious disease: bacterial", "children":[ { "name":"05110 Vibrio cholerae infection" }, { "name":"05120 Epithelial cell signaling in Helicobacter pylori infection" }, { "name":"05130 Pathogenic Escherichia coli infection" }, { "name":"05132 Salmonella infection" }, { "name":"05131 Shigellosis" }, { "name":"05135 Yersinia infection" }, { "name":"05133 Pertussis" }, { "name":"05134 Legionellosis" }, { "name":"05150 Staphylococcus aureus infection" }, { "name":"05152 Tuberculosis" }, { "name":"05100 Bacterial invasion of epithelial cells" } ] }, { "name":"09174 Infectious disease: parasitic", "children":[ { "name":"05146 Amoebiasis" }, { "name":"05144 Malaria" }, { "name":"05145 Toxoplasmosis" }, { "name":"05140 Leishmaniasis" }, { "name":"05142 Chagas disease" }, { "name":"05143 African trypanosomiasis" } ] }, { "name":"09163 Immune disease", "children":[ { "name":"05310 Asthma" }, { "name":"05322 Systemic lupus erythematosus" }, { "name":"05323 Rheumatoid arthritis" }, { "name":"05320 Autoimmune thyroid disease" }, { "name":"05321 Inflammatory bowel disease" }, { "name":"05330 Allograft rejection" }, { "name":"05332 Graft-versus-host disease" }, { "name":"05340 Primary immunodeficiency" } ] }, { "name":"09164 Neurodegenerative disease", "children":[ { "name":"05010 Alzheimer disease" }, { "name":"05012 Parkinson disease" }, { "name":"05014 Amyotrophic lateral sclerosis" }, { "name":"05016 Huntington disease" }, { "name":"05017 Spinocerebellar ataxia" }, { "name":"05020 Prion disease" }, { "name":"05022 Pathways of neurodegeneration - multiple diseases" } ] }, { "name":"09165 Substance dependence", "children":[ { "name":"05030 Cocaine addiction" }, { "name":"05031 Amphetamine addiction" }, { "name":"05032 Morphine addiction" }, { "name":"05033 Nicotine addiction" }, { "name":"05034 Alcoholism" } ] }, { "name":"09166 Cardiovascular disease", "children":[ { "name":"05417 Lipid and atherosclerosis" }, { "name":"05418 Fluid shear stress and atherosclerosis" }, { "name":"05410 Hypertrophic cardiomyopathy" }, { "name":"05412 Arrhythmogenic right ventricular cardiomyopathy" }, { "name":"05414 Dilated cardiomyopathy" }, { "name":"05415 Diabetic cardiomyopathy" }, { "name":"05416 Viral myocarditis" } ] }, { "name":"09167 Endocrine and metabolic disease", "children":[ { "name":"04930 Type II diabetes mellitus" }, { "name":"04940 Type I diabetes mellitus" }, { "name":"04950 Maturity onset diabetes of the young" }, { "name":"04936 Alcoholic liver disease" }, { "name":"04932 Non-alcoholic fatty liver disease" }, { "name":"04931 Insulin resistance" }, { "name":"04933 AGE-RAGE signaling pathway in diabetic complications" }, { "name":"04934 Cushing syndrome" } ] }, { "name":"09175 Drug resistance: antimicrobial", "children":[ { "name":"01501 beta-Lactam resistance [PATH:nio01501]", "children":[ { "name":"NITINOP_2041 ampG; muropeptide transporter\tK08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG" }, { "name":"NITINOP_1096 nagZ; Beta-N-acetylglucosaminidase\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]" }, { "name":"NITINOP_0166 ttgA; Toluene efflux pump periplasmic linker protein TtgA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0321 putative Acriflavine resistance protein acrA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0715 putative RND-type efflux transporter, membrane-fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_1220 putative RND efflux system, membrane fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0165 acrB; multidrug efflux system protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0322 acrB; Acriflavin resistance protein acrB\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0714 putative RND-type efflux transporter, transmembrane pump\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_1221 putative RND efflux system, multidrug resistance protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0164 oprM; Outer membrane protein OprM\tK18139 oprM; outer membrane protein, multidrug efflux system" }, { "name":"NITINOP_0013 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0713 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3265 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0516 mrcA; Penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"NITINOP_0086 mrdA; Penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" }, { "name":"NITINOP_0302 ftsI; Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" } ] }, { "name":"01502 Vancomycin resistance [PATH:nio01502]", "children":[ { "name":"NITINOP_0293 ddlB; D-alanine:D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"NITINOP_2459 alr; Alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]" }, { "name":"NITINOP_0300 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]" }, { "name":"NITINOP_0299 mraY; phospho-N-acetylmuramoyl-pentapeptide transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"NITINOP_0296 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" } ] }, { "name":"01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:nio01503]", "children":[ { "name":"NITINOP_3071 putative N-acetylmuramoyl-L-alanine amidase AmiB\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" }, { "name":"NITINOP_0368 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1009 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1962 degP; Protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_2660 putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_3076 degQ; Protease DegQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_0389 putative Disulfide oxidoreductase dsbA\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]" }, { "name":"NITINOP_0166 ttgA; Toluene efflux pump periplasmic linker protein TtgA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0321 putative Acriflavine resistance protein acrA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0715 putative RND-type efflux transporter, membrane-fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_1220 putative RND efflux system, membrane fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0165 acrB; multidrug efflux system protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0322 acrB; Acriflavin resistance protein acrB\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0714 putative RND-type efflux transporter, transmembrane pump\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_1221 putative RND efflux system, multidrug resistance protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0013 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0713 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3265 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3133 lpxA; UDP-N-acetylglucosamine acetyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" } ] } ] }, { "name":"09176 Drug resistance: antineoplastic", "children":[ { "name":"01521 EGFR tyrosine kinase inhibitor resistance" }, { "name":"01524 Platinum drug resistance" }, { "name":"01523 Antifolate resistance" }, { "name":"01522 Endocrine resistance" } ] } ] }, { "name":"09180 Brite Hierarchies", "children":[ { "name":"09181 Protein families: metabolism", "children":[ { "name":"01000 Enzymes [BR:nio01000]" }, { "name":"01001 Protein kinases [BR:nio01001]", "children":[ { "name":"NITINOP_1999 putative serine\/threonine protein kinase\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"NITINOP_2390 putative Lipopolysaccharide biosynthesis protein\tK16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]" }, { "name":"NITINOP_0406 putative Exopolysaccharide biosynthesis related tyrosine-protein kinase\tK00903 epsB; protein-tyrosine kinase [EC:2.7.10.3]" }, { "name":"NITINOP_1564 putative Phosphate regulon sensor histidine kinase PhoR\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]" }, { "name":"NITINOP_1506 kdpD; fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein; sensory histidine kinase\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]" }, { "name":"NITINOP_2339 putative Histidine kinase\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]" }, { "name":"NITINOP_2230 Sensor histidine kinase\tK13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]" }, { "name":"NITINOP_0280 putative Sensor protein PilS\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"NITINOP_2114 putative Sensor histidine kinase\tK07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]" }, { "name":"NITINOP_1547 putative Histidine kinase\tK02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]" }, { "name":"NITINOP_2284 cheA; fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase; signal sensing protein\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]" }, { "name":"NITINOP_2560 putative Histidine kinase\tK06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase\/response regulator)" }, { "name":"NITINOP_0183 Putative Hybrid sensor histidine kinase (fragment)\tK13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]" }, { "name":"NITINOP_1121 putative Hybrid histidine kinase\tK13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]" } ] }, { "name":"01009 Protein phosphatases and associated proteins [BR:nio01009]", "children":[ { "name":"NITINOP_1556 ahcY; Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"NITINOP_2810 conserved protein of unknown function\tK20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]" } ] }, { "name":"01002 Peptidases and inhibitors [BR:nio01002]", "children":[ { "name":"NITINOP_1926 lspA; Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]" }, { "name":"NITINOP_1145 pilD; Type 4 prepilin-like proteins leader peptide-processing enzyme\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"NITINOP_0585 hybD; Hydrogenase maturation protease\tK03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]" }, { "name":"NITINOP_1828 guaA; GMP synthetase (glutamine aminotransferase)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]" }, { "name":"NITINOP_1090 putative Gamma-glutamyl-gamma-aminobutyrate hydrolase\tK07010 K07010; putative glutamine amidotransferase" }, { "name":"NITINOP_1804 purF; Amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" }, { "name":"NITINOP_3380 gltB; glutamate synthase, large subunit\tK00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]" }, { "name":"NITINOP_2367 glmS; L-glutamine:D-fructose-6-phosphate aminotransferase\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"NITINOP_0434 Asparagine synthetase\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"NITINOP_2394 Asparagine synthetase\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"NITINOP_2425 Asparagine synthetase\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"NITINOP_2623 conserved membrane protein of unknown function\tK07052 K07052; CAAX protease family protein" }, { "name":"NITINOP_1162 putative Peptidase M\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]" }, { "name":"NITINOP_3281 putative Oligoendopeptidase F\tK08602 pepF; oligoendopeptidase F [EC:3.4.24.-]" }, { "name":"NITINOP_1392 putative Zn-dependent peptidase, M16 family\tK07263 pqqL; zinc protease [EC:3.4.24.-]" }, { "name":"NITINOP_1393 putative Zn-dependent peptidase, M16 family\tK07263 pqqL; zinc protease [EC:3.4.24.-]" }, { "name":"NITINOP_1497 putative Peptidase M16\tK07263 pqqL; zinc protease [EC:3.4.24.-]" }, { "name":"NITINOP_1097 pepA; putative cytosol aminopeptidase\tK01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]" }, { "name":"NITINOP_1753 map; Methionine aminopeptidase\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]" }, { "name":"NITINOP_2162 pepP; Xaa-Pro aminopeptidase\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]" }, { "name":"NITINOP_1893 Thermostable carboxypeptidase 1\tK01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]" }, { "name":"NITINOP_0656 ftsH; ATP-dependent zinc metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"NITINOP_2485 ftsH; protease, ATP-dependent zinc-metallo\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"NITINOP_3227 htpX; Protease HtpX\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]" }, { "name":"NITINOP_1981 ecfE; Peptidase M50\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]" }, { "name":"NITINOP_1301 conserved exported protein of unknown function\tK16203 dppA1; D-amino peptidase [EC:3.4.11.-]" }, { "name":"NITINOP_0368 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1009 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1962 degP; Protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_2660 putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_3076 degQ; Protease DegQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1300 putative D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]" }, { "name":"NITINOP_0284 putative Esterase, beta-lactamase family\tK21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]" }, { "name":"NITINOP_1082 clpP; ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) (Caseinolytic protease) (Protease Ti) (Heat shock protein F21.5)\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]" }, { "name":"NITINOP_2024 lon; Lon protease\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]" }, { "name":"NITINOP_3140 lon; DNA-binding ATP-dependent protease La\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]" }, { "name":"NITINOP_2932 putative Repressor LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]" }, { "name":"NITINOP_3190 lexA; LexA repressor\tK01356 lexA; repressor LexA [EC:3.4.21.88]" }, { "name":"NITINOP_2872 lepB; Signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]" }, { "name":"NITINOP_3247 ctpA; Carboxy-terminal-processing protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]" }, { "name":"NITINOP_1293 putative Peptidase S49, signal peptide peptidase SppA\tK04773 sppA; protease IV [EC:3.4.21.-]" }, { "name":"NITINOP_2880 putative Signal peptide peptidase SppA\tK04773 sppA; protease IV [EC:3.4.21.-]" }, { "name":"NITINOP_0485 putative Rhomboid serine protease\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]" }, { "name":"NITINOP_1620 putative Proteasome, alpha subunit\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]" }, { "name":"NITINOP_3238 prcA; Proteasome subunit alpha\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]" }, { "name":"NITINOP_1619 putative Proteasome, beta subunit\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]" }, { "name":"NITINOP_3239 prcB; Proteasome subunit beta\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]" }, { "name":"NITINOP_1071 hslV; peptidase component of the HslUV protease\tK01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]" }, { "name":"NITINOP_1464 iaaA; Isoaspartyl peptidase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]" }, { "name":"NITINOP_1986 pmbA; Peptidase U62\tK03592 pmbA; PmbA protein" }, { "name":"NITINOP_0809 conserved protein of unknown function\tK03568 tldD; TldD protein" }, { "name":"NITINOP_1985 tldD; putative peptidase\tK03568 tldD; TldD protein" }, { "name":"NITINOP_1514 hflC; Protein HflC\tK04087 hflC; modulator of FtsH protease HflC" }, { "name":"NITINOP_1515 hflK; FtsH protease activity modulator HflK\tK04088 hflK; modulator of FtsH protease HflK" } ] }, { "name":"01003 Glycosyltransferases [BR:nio01003]", "children":[ { "name":"NITINOP_2793 Undecaprenyl-phosphate mannosyltransferase (modular protein)\tK00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]" }, { "name":"NITINOP_0433 putative Phosphatidylinositol alpha-mannosyltransferase\tK13668 pimB; phosphatidyl-myo-inositol dimannoside synthase [EC:2.4.1.346]" }, { "name":"NITINOP_1689 Glycosyltransferase\tK27597 K27597; 1,2-diacylglycerol 3-alpha-glucosyltransferase\/glucuronosyltransferase [EC:2.4.1.337 2.4.1.-]" }, { "name":"NITINOP_2381 glgA; Glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]" }, { "name":"NITINOP_1465 mtgA; Monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_1542 putative Penicillin-binding protein 1B\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]" }, { "name":"NITINOP_0516 mrcA; Penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"NITINOP_0297 ftsW; integral membrane protein involved in stabilizing FstZ ring during cell division\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0085 mrdB; cell wall shape-determining protein\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0411 putative Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (Modular protein)\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"NITINOP_2747 otsA; Alpha,alpha-trehalose-phosphate synthase (UDP-forming)\tK00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347]" }, { "name":"NITINOP_2744 gpgS; Glucosyl-3-phosphoglycerate synthase\tK13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266]" } ] }, { "name":"01005 Lipopolysaccharide biosynthesis proteins [BR:nio01005]", "children":[ { "name":"NITINOP_3133 lpxA; UDP-N-acetylglucosamine acetyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" }, { "name":"NITINOP_3130 lpxB; Lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]" }, { "name":"NITINOP_1448 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase\tK02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]" }, { "name":"NITINOP_2564 lpxD; UDP-3-O-acylglucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]" }, { "name":"NITINOP_3132 conserved protein of unknown function\tK09949 lpxI; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]" }, { "name":"NITINOP_3125 lpxK; Tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]" }, { "name":"NITINOP_3126 waaA; 3-deoxy-D-manno-octulosonic-acid transferase\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]" }, { "name":"NITINOP_0025 exported protein of unknown function\tK12976 pagL; lipid A 3-O-deacylase [EC:3.1.1.-]" }, { "name":"NITINOP_2868 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]" }, { "name":"NITINOP_2870 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]" }, { "name":"NITINOP_3082 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]" }, { "name":"NITINOP_2867 kdsD; D-arabinose 5-phosphate isomerase\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]" }, { "name":"NITINOP_2871 rfaEa; D-beta-D-heptose 7-phosphate kinase, domain I of bifunctional protein HldE\tK21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]" }, { "name":"NITINOP_1470 rfaEb; D-beta-D-heptose 1-phosphate adenosyltransferase\tK21345 rfaE2; D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase [EC:2.7.7.70]" }, { "name":"NITINOP_3124 gmhB; Lipopolysaccharide heptosyltransferase II and D, D-heptose 1,7-bisphosphate phosphatase (Modular protein)\tK02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]" }, { "name":"NITINOP_3087 putative lipopolysaccharide heptosyltransferase III\tK02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25]" }, { "name":"NITINOP_1473 gmhA; Phosphoheptose isomerase\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]" }, { "name":"NITINOP_0355 hldD; ADP-L-glycero-D-manno-heptose-6-epimerase\tK03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]" }, { "name":"NITINOP_0411 putative Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (Modular protein)\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"01011 Peptidoglycan biosynthesis and degradation proteins [BR:nio01011]", "children":[ { "name":"NITINOP_0123 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"NITINOP_0294 murB; UDP-N-acetylenolpyruvoylglucosamine reductase 2\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"NITINOP_0295 murC; UDP-N-acetylmuramate:L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]" }, { "name":"NITINOP_0298 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"NITINOP_0301 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]" }, { "name":"NITINOP_0293 ddlB; D-alanine:D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"NITINOP_2459 alr; Alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]" }, { "name":"NITINOP_0299 mraY; phospho-N-acetylmuramoyl-pentapeptide transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"NITINOP_0296 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" }, { "name":"NITINOP_1928 uppP; Undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"NITINOP_1460 mviN; Protein MurJ homolog\tK03980 murJ; putative peptidoglycan lipid II flippase" }, { "name":"NITINOP_0516 mrcA; Penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"NITINOP_1542 putative Penicillin-binding protein 1B\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]" }, { "name":"NITINOP_0086 mrdA; Penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" }, { "name":"NITINOP_0302 ftsI; Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" }, { "name":"NITINOP_1300 putative D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]" }, { "name":"NITINOP_0284 putative Esterase, beta-lactamase family\tK21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]" }, { "name":"NITINOP_1465 mtgA; Monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0297 ftsW; integral membrane protein involved in stabilizing FstZ ring during cell division\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0085 mrdB; cell wall shape-determining protein\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_1395 putative Soluble lytic murein transglycosylase\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]" }, { "name":"NITINOP_1238 conserved exported protein of unknown function\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]" }, { "name":"NITINOP_2640 Putative Lytic murein transglycosylase (fragment)\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]" }, { "name":"NITINOP_2531 conserved protein of unknown function\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]" }, { "name":"NITINOP_1703 conserved protein of unknown function\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]" }, { "name":"NITINOP_2056 putative lipoprotein, RlpA-like\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]" }, { "name":"NITINOP_0094 putative Amidase enhancer protein LytB\tK06381 spoIID; stage II sporulation protein D (peptidoglycan lytic transglycosylase) [EC:4.2.2.29]" }, { "name":"NITINOP_3071 putative N-acetylmuramoyl-L-alanine amidase AmiB\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" } ] }, { "name":"01004 Lipid biosynthesis proteins [BR:nio01004]", "children":[ { "name":"NITINOP_0259 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"NITINOP_0260 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"NITINOP_1563 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase 3\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"NITINOP_0204 Beta-ketoacyl synthase\tK00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]" }, { "name":"NITINOP_0256 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"NITINOP_2566 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"NITINOP_0161 Uncharacterized oxidoreductase MexAM1_META1p0182\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0192 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0201 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0258 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2238 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_2516 fabG; 3-oxoacyl-(Acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"NITINOP_0208 protein of unknown function\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"NITINOP_3134 fabZ; (3R)-hydroxymyristol acyl carrier protein dehydratase\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"NITINOP_0846 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]" }, { "name":"NITINOP_0887 Esterase TesA (modular protein)\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]" }, { "name":"NITINOP_2004 conserved protein of unknown function\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]" }, { "name":"NITINOP_2216 desC; Fatty acid desaturase, type 1\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]" }, { "name":"NITINOP_3351 scdA; Stearoyl-CoA 9-desaturase\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]" }, { "name":"NITINOP_2186 acsA; Acetyl-CoA synthetase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"NITINOP_0743 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0933 putative 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0261 plsX; Phosphate acyltransferase\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]" }, { "name":"NITINOP_2864 plsY; Glycerol-3-phosphate acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"NITINOP_1291 putative Acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"NITINOP_1670 putative Phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" } ] }, { "name":"01008 Polyketide biosynthesis proteins" }, { "name":"01006 Prenyltransferases [BR:nio01006]", "children":[ { "name":"NITINOP_0337 Farnesyl diphosphate synthase (modular protein)\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"NITINOP_3381 ispB; Octaprenyl-diphosphate synthase\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]" }, { "name":"NITINOP_1984 ispU; undecaprenyl pyrophosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" }, { "name":"NITINOP_3226 Farnesyl-diphosphate farnesyltransferase\tK00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]" }, { "name":"NITINOP_1991 crtB; Phytoene synthase\tK02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]" }, { "name":"NITINOP_1953 miaA; tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]" }, { "name":"NITINOP_1600 ubiA; 4-hydroxybenzoate octaprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]" } ] }, { "name":"01007 Amino acid related enzymes [BR:nio01007]", "children":[ { "name":"NITINOP_0506 gltX; Glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"NITINOP_0504 glnS; glutamyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"NITINOP_2495 tyrS; Tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"NITINOP_1940 trpS; Tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" }, { "name":"NITINOP_1142 cysS; Cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"NITINOP_3332 argS; Arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"NITINOP_2362 metG; Methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"NITINOP_1925 ileS; isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"NITINOP_2728 valS; Valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"NITINOP_1413 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"NITINOP_2074 lysU; lysine tRNA synthetase, inducible\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"NITINOP_1830 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"NITINOP_0996 hisS; Histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"NITINOP_2178 glyQ; glycyl-tRNA synthetase, alpha chain\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"NITINOP_2179 glyS; Glycine--tRNA ligase beta subunit\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"NITINOP_2833 serS; Serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"NITINOP_1980 proS; prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"NITINOP_1269 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"NITINOP_2529 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"NITINOP_1263 pheS; Phenylalanine--tRNA ligase alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"NITINOP_1264 pheT; Phenylalanyl-tRNA synthetase, beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"NITINOP_2668 aspC; Aspartate aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"NITINOP_0771 yfdZ; putative aminotransferase, PLP-dependent\tK14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-]" }, { "name":"NITINOP_1231 dapL; LL-diaminopimelate aminotransferase\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]" }, { "name":"NITINOP_0803 Aminotransferase\tK10907 K10907; aminotransferase [EC:2.6.1.-]" }, { "name":"NITINOP_1286 hisC; Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"NITINOP_1659 kbl; glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]" }, { "name":"NITINOP_2638 bioF; 8-amino-7-oxononanoate synthase\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]" }, { "name":"NITINOP_1252 argD; Acetylornithine aminotransferase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]" }, { "name":"NITINOP_2875 bioA; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase\tK00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]" }, { "name":"NITINOP_1492 hemL; glutamate-1-semialdehyde aminotransferase (aminomutase)\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]" }, { "name":"NITINOP_1691 Aminotransferase class-III (modular protein)\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]" }, { "name":"NITINOP_0789 dat; D-alanine aminotransferase\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" }, { "name":"NITINOP_1385 ilvE; putative branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_3162 ilvE; Branched-chain-amino-acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"NITINOP_0315 phnW; 2-aminoethylphosphonate aminotransferase\tK03430 phnW; 2-aminoethylphosphonate-pyruvate transaminase [EC:2.6.1.37]" } ] }, { "name":"00199 Cytochrome P450" }, { "name":"00194 Photosynthesis proteins [BR:nio00194]", "children":[ { "name":"NITINOP_0692 H+transporting two-sector ATPase delta\/epsilon subunit\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"NITINOP_1182 atpC; ATP synthase epsilon chain\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"NITINOP_0693 atpD; F1 sector of membrane-bound ATP synthase, beta subunit\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_1181 atpD; membrane-bound ATP synthase, F1 sector, beta-subunit\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_0682 ATP synthase gamma subunit C-terminus\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"NITINOP_1180 atpG; ATP synthase gamma chain\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"NITINOP_0687 atpA; F1 sector of membrane-bound ATP synthase, alpha subunit\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_1179 atpA; F1 sector of membrane-bound ATP synthase, alpha subunit\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"NITINOP_1178 atpH; ATP synthase subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta" }, { "name":"NITINOP_0688 atpF; ATP synthase subunit b\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"NITINOP_1390 atpF; ATP synthase subunit b\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"NITINOP_0689 atpE; ATP synthase subunit c 2\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"NITINOP_1389 atpE; ATP synthase subunit c\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"NITINOP_0690 atpB; ATP synthase subunit a 2\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"NITINOP_1388 atpB; ATP synthase subunit a\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"NITINOP_0691 ATP synthase (modular protein)\tK02116 atpI; ATP synthase protein I" }, { "name":"NITINOP_1387 Putative ATP synthase F0, subunit I (fragment)\tK02116 atpI; ATP synthase protein I" } ] } ] }, { "name":"09182 Protein families: genetic information processing", "children":[ { "name":"03000 Transcription factors [BR:nio03000]", "children":[ { "name":"NITINOP_2046 dcm; Cytosine-specific methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"NITINOP_0493 Transcriptional regulator, LysR family\tK03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA" }, { "name":"NITINOP_1432 oxyR; Hydrogen peroxide-inducible genes activator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator" }, { "name":"NITINOP_1359 aubR; Transcriptional regulator\tK20334 cviR; LuxR family transcriptional regulator, quorum-sensing system regulator CviR" }, { "name":"NITINOP_2976 Transcriptional regulator, MerR family\tK19591 cueR; MerR family transcriptional regulator, copper efflux regulator" }, { "name":"NITINOP_1135 putative Regulatory protein, MerR family, Cobalamin B12-binding\tK22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator" }, { "name":"NITINOP_1891 fur; Ferric uptake regulation protein\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator" }, { "name":"NITINOP_3067 Transcriptional regulator, Fur family\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator" }, { "name":"NITINOP_1272 putative HTH-type transcriptional regulator, rrf2 family\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor" }, { "name":"NITINOP_2730 putative Biotin-(Acetyl-CoA-carboxylase) ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]" }, { "name":"NITINOP_1223 DNA-binding protein\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA" }, { "name":"NITINOP_0169 Formate hydrogenlyase transcriptional activator (fragment)\tK15836 fhlA; formate hydrogenlyase transcriptional activator" }, { "name":"NITINOP_0359 putative nickel-responsive regulator\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator" }, { "name":"NITINOP_2240 putA; Bifunctional protein PutA\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]" }, { "name":"NITINOP_0900 parB; putative chromosome-partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"NITINOP_1439 conserved exported protein of unknown function\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"NITINOP_2393 putative Transcription antitermination protein RfaH\tK05785 rfaH; transcriptional antiterminator RfaH" }, { "name":"NITINOP_2201 putative Thiaminase\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]" }, { "name":"NITINOP_2885 pyrR; Bifunctional protein PyrR [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase]\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]" }, { "name":"NITINOP_3172 conserved exported protein of unknown function\tK07735 algH; putative transcriptional regulator" }, { "name":"NITINOP_3271 conserved protein of unknown function\tK07735 algH; putative transcriptional regulator" }, { "name":"NITINOP_1076 putative RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_1668 protein of unknown function\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_3215 dksA; DnaK suppressor protein (Modular protein)\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_1662 nrdR; Transcriptional repressor NrdR\tK07738 nrdR; transcriptional repressor NrdR" }, { "name":"NITINOP_2768 mraZ; Protein MraZ\tK03925 mraZ; transcriptional regulator MraZ" } ] }, { "name":"03021 Transcription machinery [BR:nio03021]", "children":[ { "name":"NITINOP_1759 rpoA; RNA polymerase, alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"NITINOP_1722 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"NITINOP_1723 rpoC; RNA polymerase, beta prime subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"NITINOP_2783 rpoZ; DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]" }, { "name":"NITINOP_0110 rpoD; RNA polymerase, sigma 70 (sigma D) factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"NITINOP_1305 rpoD; RNA polymerase sigma factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"NITINOP_0361 sigK; RNA polymerase sigma factor SigK (Sigma-K)\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily" }, { "name":"NITINOP_1532 conserved protein of unknown function\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily" }, { "name":"NITINOP_2613 rpoE; RNA polymerase sigma factor\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily" }, { "name":"NITINOP_2684 sigZ; RNA polymerase sigma factor SigZ (Sigma Z)\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily" }, { "name":"NITINOP_1792 rpoH; RNA polymerase sigma factor\tK03089 rpoH; RNA polymerase sigma-32 factor" }, { "name":"NITINOP_1765 rpoN; RNA polymerase, sigma-54 (Sigma N) factor\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"NITINOP_2148 fliA; RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" }, { "name":"NITINOP_0787 nusA; Transcription termination\/antitermination protein NusA\tK02600 nusA; transcription termination\/antitermination protein NusA" }, { "name":"NITINOP_1795 nusB; N utilization substance protein B homolog\tK03625 nusB; transcription antitermination protein NusB" }, { "name":"NITINOP_1718 nusG; transcription termination factor\tK02601 nusG; transcription termination\/antitermination protein NusG" }, { "name":"NITINOP_1076 putative RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_1668 protein of unknown function\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_3215 dksA; DnaK suppressor protein (Modular protein)\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_2877 greA; transcription elongation factor\tK03624 greA; transcription elongation factor GreA" }, { "name":"NITINOP_0127 rho; transcription termination factor\tK03628 rho; transcription termination factor Rho" } ] }, { "name":"03019 Messenger RNA biogenesis [BR:nio03019]", "children":[ { "name":"NITINOP_0084 rng; ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]" }, { "name":"NITINOP_0255 rnc; Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"NITINOP_1399 rny; Ribonuclease Y\tK18682 rny; ribonucrease Y [EC:3.1.-.-]" }, { "name":"NITINOP_0920 deaD; ATP-dependent RNA helicase DeaD\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]" }, { "name":"NITINOP_2374 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"NITINOP_0781 pnp; polynucleotide phosphorylase\/polyadenylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"NITINOP_0127 rho; transcription termination factor\tK03628 rho; transcription termination factor Rho" }, { "name":"NITINOP_0514 dnaK; chaperone Hsp70, co-chaperone with DnaJ\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_2540 dnaK; chaperone Hsp70 in DNA biosynthesis\/cell division\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_1790 groEL; chaperone Hsp60, peptide-dependent ATPase, heat shock protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"NITINOP_0636 putative Polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" }, { "name":"NITINOP_2159 csrA; Carbon storage regulator homolog\tK03563 csrA; carbon storage regulator" }, { "name":"NITINOP_1767 conserved protein of unknown function\tK06958 rapZ; RNase adapter protein RapZ" }, { "name":"NITINOP_2588 hrpB; ATP-dependent RNA helicase HrpB\tK03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6]" } ] }, { "name":"03041 Spliceosome" }, { "name":"03011 Ribosome [BR:nio03011]", "children":[ { "name":"NITINOP_1292 rpsA; 30S ribosomal subunit protein S1\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"NITINOP_2463 rpsB; 30S ribosomal subunit protein S2\tK02967 RP-S2; small subunit ribosomal protein S2" }, { "name":"NITINOP_1735 rpsC; 30S ribosomal subunit protein S3\tK02982 RP-S3; small subunit ribosomal protein S3" }, { "name":"NITINOP_1758 rpsD; 30S ribosomal subunit protein S4\tK02986 RP-S4; small subunit ribosomal protein S4" }, { "name":"NITINOP_1748 rpsE; 30S ribosomal subunit protein S5\tK02988 RP-S5; small subunit ribosomal protein S5" }, { "name":"NITINOP_0266 rpsF; 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6" }, { "name":"NITINOP_1725 rpsG; 30S ribosomal subunit protein S7\tK02992 RP-S7; small subunit ribosomal protein S7" }, { "name":"NITINOP_1745 rpsH; 30S ribosomal subunit protein S8\tK02994 RP-S8; small subunit ribosomal protein S8" }, { "name":"NITINOP_2468 rpsI; 30S ribosomal subunit protein S9\tK02996 RP-S9; small subunit ribosomal protein S9" }, { "name":"NITINOP_1728 rpsJ; 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10" }, { "name":"NITINOP_1756 rpsK; 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11" }, { "name":"NITINOP_1724 rpsL; 30S ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12" }, { "name":"NITINOP_1755 rpsM; 30S ribosomal subunit protein S13\tK02952 RP-S13; small subunit ribosomal protein S13" }, { "name":"NITINOP_1743 rpsZ; 30S ribosomal protein S14 type Z\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"NITINOP_2333 rpsN; 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"NITINOP_0782 rpsO; 30S ribosomal subunit protein S15\tK02956 RP-S15; small subunit ribosomal protein S15" }, { "name":"NITINOP_3256 rpsP; 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16" }, { "name":"NITINOP_1739 rpsQ; 30S ribosomal subunit protein S17\tK02961 RP-S17; small subunit ribosomal protein S17" }, { "name":"NITINOP_0264 rpsR; 30S ribosomal subunit protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"NITINOP_2332 rpsR; 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"NITINOP_1733 rpsS; 30S ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19" }, { "name":"NITINOP_1416 rpsT; 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20" }, { "name":"NITINOP_1641 rpsU; 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21" }, { "name":"NITINOP_1720 rplA; 50S ribosomal subunit protein L1\tK02863 RP-L1; large subunit ribosomal protein L1" }, { "name":"NITINOP_1732 rplB; 50S ribosomal subunit protein L2\tK02886 RP-L2; large subunit ribosomal protein L2" }, { "name":"NITINOP_1729 rplC; 50S ribosomal subunit protein L3\tK02906 RP-L3; large subunit ribosomal protein L3" }, { "name":"NITINOP_1730 rplD; 50S ribosomal subunit protein L4\tK02926 RP-L4; large subunit ribosomal protein L4" }, { "name":"NITINOP_1742 rplE; 50S ribosomal subunit protein L5\tK02931 RP-L5; large subunit ribosomal protein L5" }, { "name":"NITINOP_1746 rplF; 50S ribosomal subunit protein L6\tK02933 RP-L6; large subunit ribosomal protein L6" }, { "name":"NITINOP_1660 rplI; 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9" }, { "name":"NITINOP_1719 rplK; 50S ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11" }, { "name":"NITINOP_1721 rplJL; Fused 50S ribosomal proteins L10 and L7\/L12 (Modular protein)\tK02935 RP-L7; large subunit ribosomal protein L7\/L12" }, { "name":"NITINOP_2469 rplM; 50S ribosomal subunit protein L13\tK02871 RP-L13; large subunit ribosomal protein L13" }, { "name":"NITINOP_1740 rplN; 50S ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14" }, { "name":"NITINOP_1750 rplO; 50S ribosomal subunit protein L15\tK02876 RP-L15; large subunit ribosomal protein L15" }, { "name":"NITINOP_1736 rplP; 50S ribosomal subunit protein L16\tK02878 RP-L16; large subunit ribosomal protein L16" }, { "name":"NITINOP_1760 rplQ; 50S ribosomal subunit protein L17\tK02879 RP-L17; large subunit ribosomal protein L17" }, { "name":"NITINOP_1747 rplR; 50S ribosomal subunit protein L18\tK02881 RP-L18; large subunit ribosomal protein L18" }, { "name":"NITINOP_3253 rplS; 50S ribosomal subunit protein L19\tK02884 RP-L19; large subunit ribosomal protein L19" }, { "name":"NITINOP_1266 rplT; 50S ribosomal subunit protein L20\tK02887 RP-L20; large subunit ribosomal protein L20" }, { "name":"NITINOP_3164 rplU; 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21" }, { "name":"NITINOP_1734 rplV; 50S ribosomal subunit protein L22\tK02890 RP-L22; large subunit ribosomal protein L22" }, { "name":"NITINOP_1731 rplW; 50S ribosomal subunit protein L23\tK02892 RP-L23; large subunit ribosomal protein L23" }, { "name":"NITINOP_1741 rplX; 50S ribosomal subunit protein L24\tK02895 RP-L24; large subunit ribosomal protein L24" }, { "name":"NITINOP_3165 rpmA; 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27" }, { "name":"NITINOP_2336 rpmB; 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"NITINOP_2544 rpmB; 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"NITINOP_1737 rpmC; 50S ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29" }, { "name":"NITINOP_1749 rpmD; 50S ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30" }, { "name":"NITINOP_0126 rpmE; 50S ribosomal subunit protein L31\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"NITINOP_2334 rpmE; 50S ribosomal protein L31 type B\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"NITINOP_0262 rpmF; 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32" }, { "name":"NITINOP_1716 rpmG; 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"NITINOP_2337 rpmG; 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"NITINOP_1267 rpmI; 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35" }, { "name":"NITINOP_0275 rplY; 50S ribosomal protein L25\tK02897 RP-L25; large subunit ribosomal protein L25" }, { "name":"NITINOP_23s_rRNA1 ribosomal RNA 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"NITINOP_5s_rRNA_1 ribosomal RNA 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" } ] }, { "name":"03009 Ribosome biogenesis [BR:nio03009]", "children":[ { "name":"NITINOP_0255 rnc; Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"NITINOP_2376 era; GTPase Era\tK03595 era; GTPase" }, { "name":"NITINOP_3166 obg; GTPase Obg\tK03979 obgE; GTPase [EC:3.6.5.-]" }, { "name":"NITINOP_1076 putative RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_1668 protein of unknown function\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_3215 dksA; DnaK suppressor protein (Modular protein)\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"NITINOP_0787 nusA; Transcription termination\/antitermination protein NusA\tK02600 nusA; transcription termination\/antitermination protein NusA" }, { "name":"NITINOP_1795 nusB; N utilization substance protein B homolog\tK03625 nusB; transcription antitermination protein NusB" }, { "name":"NITINOP_1718 nusG; transcription termination factor\tK02601 nusG; transcription termination\/antitermination protein NusG" }, { "name":"NITINOP_1196 rsmA; Ribosomal RNA small subunit methyltransferase A\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]" }, { "name":"NITINOP_1261 rsmB; Ribosomal RNA small subunit methyltransferase B\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]" }, { "name":"NITINOP_2666 putative Ribosomal RNA small subunit methyltransferase D\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]" }, { "name":"NITINOP_2538 Ribosomal RNA small subunit methyltransferase E\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]" }, { "name":"NITINOP_0902 putative Ribosomal RNA small subunit methyltransferase G\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]" }, { "name":"NITINOP_0304 mraW; S-adenosyl-dependent methyltransferase activity on membrane-located substrates\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]" }, { "name":"NITINOP_2475 putative Ribosomal RNA small subunit methyltransferase I\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]" }, { "name":"NITINOP_1403 tlyA; 16S\/23S rRNA (cytidine-2'-O)-methyltransferase TlyA\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]" }, { "name":"NITINOP_1143 yacO; putative TrmH family tRNA\/rRNA methyltransferase YacO\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]" }, { "name":"NITINOP_2196 yccW; putative Methyltransferase with PUA domain\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]" }, { "name":"NITINOP_1394 rlmN; Dual-specificity RNA methyltransferase RlmN\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]" }, { "name":"NITINOP_1829 rluB; Ribosomal large subunit pseudouridine synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]" }, { "name":"NITINOP_1183 Uncharacterized RNA pseudouridine synthase aq_1758\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]" }, { "name":"NITINOP_3282 ymfC; 23S rRNA pseudouridine synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]" }, { "name":"NITINOP_0494 Pseudouridine synthase\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]" }, { "name":"NITINOP_2799 rimI; Ribosomal-protein-alanine N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]" }, { "name":"NITINOP_3255 rimM; Ribosome maturation factor RimM\tK02860 rimM; 16S rRNA processing protein RimM" }, { "name":"NITINOP_1059 rimO; Ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]" }, { "name":"NITINOP_0051 prmA; Ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]" }, { "name":"NITINOP_0084 rng; ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]" }, { "name":"NITINOP_2530 Putative Holliday junction resolvase (modular protein)\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]" }, { "name":"NITINOP_0920 deaD; ATP-dependent RNA helicase DeaD\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]" }, { "name":"NITINOP_1410 der; GTPase Der\tK03977 engA; GTPase" }, { "name":"NITINOP_2787 hflX; GTPase HflX\tK03665 hflX; GTPase" }, { "name":"NITINOP_2671 putative dsRNA-binding protein, predicted ribosome maturation factor\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]" }, { "name":"NITINOP_3287 relA; GTP pyrophosphokinase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]" }, { "name":"NITINOP_0784 rbfA; 30s ribosome binding factor\tK02834 rbfA; ribosome-binding factor A" }, { "name":"NITINOP_0788 Ribosome maturation factor RimP (modular protein)\tK09748 rimP; ribosome maturation factor RimP" }, { "name":"NITINOP_3169 rsfS; Ribosomal silencing factor RsfS\tK09710 ybeB; ribosome-associated protein" }, { "name":"NITINOP_1160 ybeY; Endoribonuclease YbeY\tK07042 ybeY; probable rRNA maturation factor" }, { "name":"NITINOP_1766 yhbH; ribosome-associated, sigma 54 modulation protein\tK05808 hpf; ribosome hibernation promoting factor" }, { "name":"NITINOP_0273 ychF; putative GTP-binding protein\tK06942 ychF; ribosome-binding ATPase" }, { "name":"NITINOP_0263 conserved protein of unknown function\tK07040 yceD; DUF177 domain-containing protein" } ] }, { "name":"03016 Transfer RNA biogenesis [BR:nio03016]", "children":[ { "name":"NITINOP_3266 putative Ribonuclease Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]" }, { "name":"NITINOP_0008 Polynucleotide adenylyltransferase region\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]" }, { "name":"NITINOP_2618 conserved protein of unknown function\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]" }, { "name":"NITINOP_0749 rtcB; tRNA-splicing ligase RtcB\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]" }, { "name":"NITINOP_0748 conserved protein of unknown function\tK24956 ZBTB8OS; protein archease" }, { "name":"NITINOP_0506 gltX; Glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"NITINOP_1980 proS; prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"NITINOP_1925 ileS; isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"NITINOP_1413 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"NITINOP_2362 metG; Methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"NITINOP_0504 glnS; glutamyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"NITINOP_3332 argS; Arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"NITINOP_2074 lysU; lysine tRNA synthetase, inducible\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"NITINOP_1830 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"NITINOP_2529 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"NITINOP_1269 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"NITINOP_2833 serS; Serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"NITINOP_1142 cysS; Cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"NITINOP_2728 valS; Valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"NITINOP_0996 hisS; Histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"NITINOP_1263 pheS; Phenylalanine--tRNA ligase alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"NITINOP_1264 pheT; Phenylalanyl-tRNA synthetase, beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"NITINOP_2495 tyrS; Tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"NITINOP_1940 trpS; Tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" }, { "name":"NITINOP_1462 dtd; D-tyr-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]" }, { "name":"NITINOP_0112 Uncharacterized HIT-like protein aq_141\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]" }, { "name":"NITINOP_2036 miaB; (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]" }, { "name":"NITINOP_2037 putative tRNA modifying enzyme, MiaB-like\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]" }, { "name":"NITINOP_1308 trmI; tRNA (adenine(58)-N(1))-methyltransferase TrmI\tK07442 TRM61; tRNA (adenine57-N1\/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]" }, { "name":"NITINOP_3072 truA; tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]" }, { "name":"NITINOP_0783 truB; tRNA pseudouridine synthase B\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]" }, { "name":"NITINOP_1207 truD; tRNA pseudouridine synthase D\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]" }, { "name":"NITINOP_0510 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"NITINOP_2671 putative dsRNA-binding protein, predicted ribosome maturation factor\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]" }, { "name":"NITINOP_1953 miaA; tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]" }, { "name":"NITINOP_0904 trmE; GTPase\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]" }, { "name":"NITINOP_0903 gidA; glucose-inhibited cell-division protein\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme" }, { "name":"NITINOP_0907 rnpA; Ribonuclease P protein component\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]" }, { "name":"NITINOP_3011 rph; Ribonuclease PH\tK00989 rph; ribonuclease PH [EC:2.7.7.56]" }, { "name":"NITINOP_2318 rnd; Ribonuclease D\tK03684 rnd; ribonuclease D [EC:3.1.13.5]" }, { "name":"NITINOP_2525 putative 2'-5' RNA ligase\tK01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]" }, { "name":"NITINOP_0820 yjjK; fused putative transporter subunits of ABC superfamily: ATP-binding components\tK06020 ettA; energy-dependent translational throttle protein EttA" }, { "name":"NITINOP_2178 glyQ; glycyl-tRNA synthetase, alpha chain\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"NITINOP_2179 glyS; Glycine--tRNA ligase beta subunit\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"NITINOP_0031 tadA; tRNA-specific adenosine deaminase\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]" }, { "name":"NITINOP_1073 trmFO; Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO\tK04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]" }, { "name":"NITINOP_3254 trmD; tRNA (guanine-1-)-methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]" }, { "name":"NITINOP_3178 yibK; putative rRNA methylase\tK03216 trmL; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]" }, { "name":"NITINOP_2327 putative 23S rRNA methyltransferase RlmB\tK03437 spoU; RNA methyltransferase, TrmH family" }, { "name":"NITINOP_0897 mnmA; tRNA-specific 2-thiouridylase MnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"NITINOP_2657 putative PP-loop ATPase, YdaO type\tK21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]" }, { "name":"NITINOP_1256 ydaO; putative C32 tRNA thiolase\tK14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA" }, { "name":"NITINOP_0512 iscA; FeS cluster assembly protein\tK13628 iscA; iron-sulfur cluster assembly protein" }, { "name":"NITINOP_0093 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]" }, { "name":"NITINOP_3214 queC; 7-cyano-7-deazaguanine synthase\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]" }, { "name":"NITINOP_0531 putative 6-pyruvoyl-tetrahydropterin synthase (Modular protein)\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"NITINOP_0975 pts; 6-carboxy-5,6,7,8-tetrahydropterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"NITINOP_1098 queE; 7-carboxy-7-deazaguanine synthase\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]" }, { "name":"NITINOP_0245 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase\tK09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]" }, { "name":"NITINOP_2234 yjeS; Epoxyqueuosine reductase\tK18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]" }, { "name":"NITINOP_3331 tgt; tRNA-guanine transglycosylase\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]" }, { "name":"NITINOP_2716 thiI; putative tRNA sulfurtransferase\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]" }, { "name":"NITINOP_2483 tilS; tRNA(Ile)-lysidine synthase\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]" }, { "name":"NITINOP_2800 putative Peptidase M22\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB" }, { "name":"NITINOP_2788 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]" }, { "name":"NITINOP_0775 conserved protein of unknown function\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE" }, { "name":"NITINOP_0781 pnp; polynucleotide phosphorylase\/polyadenylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" } ] }, { "name":"03012 Translation factors [BR:nio03012]", "children":[ { "name":"NITINOP_0786 infB; Translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2" }, { "name":"NITINOP_1268 infC; protein chain initiation factor IF-3\tK02520 infC; translation initiation factor IF-3" }, { "name":"NITINOP_0970 putative ABC-type transport system, ATPase component\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3" }, { "name":"NITINOP_2462 tsf; Elongation factor Ts\tK02357 tsf; elongation factor Ts" }, { "name":"NITINOP_1715 tufB; protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"NITINOP_1727 tufB; protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"NITINOP_1726 fusA; protein chain elongation factor EF-G, GTP-binding\tK02355 fusA; elongation factor G" }, { "name":"NITINOP_2661 fusA; Elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"NITINOP_0125 prfA; peptide chain release factor RF-1\tK02835 prfA; peptide chain release factor 1" }, { "name":"NITINOP_2460 frr; ribosome recycling factor\tK02838 frr; ribosome recycling factor" }, { "name":"NITINOP_0124 prmC; Release factor glutamine methyltransferase\tK02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]" }, { "name":"NITINOP_0274 pth; Peptidyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]" }, { "name":"NITINOP_1754 infA; protein chain initiation factor IF-1\tK02518 infA; translation initiation factor IF-1" }, { "name":"NITINOP_2779 efp; Elongation factor P\tK02356 efp; elongation factor P" }, { "name":"NITINOP_2075 prfB; Peptide chain release factor 2\tK02836 prfB; peptide chain release factor 2" }, { "name":"NITINOP_2692 prfC; Peptide chain release factor 3\tK02837 prfC; peptide chain release factor 3" }, { "name":"NITINOP_0844 yaeJ; conserved hypothetical protein\tK15034 yaeJ; ribosome-associated protein" } ] }, { "name":"03110 Chaperones and folding catalysts [BR:nio03110]", "children":[ { "name":"NITINOP_2112 clpB; protein disaggregation chaperone\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB" }, { "name":"NITINOP_2789 clpC; Negative regulator of genetic competence ClpC\/MecB\tK03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC" }, { "name":"NITINOP_1083 clpX; ATP-dependent Clp protease ATP-binding subunit\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX" }, { "name":"NITINOP_1070 hslU; molecular chaperone and ATPase component of HslUV protease\tK03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU" }, { "name":"NITINOP_0514 dnaK; chaperone Hsp70, co-chaperone with DnaJ\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_2540 dnaK; chaperone Hsp70 in DNA biosynthesis\/cell division\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_1790 groEL; chaperone Hsp60, peptide-dependent ATPase, heat shock protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"NITINOP_2539 dnaJ; chaperone Hsp40, co-chaperone with DnaK\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"NITINOP_2621 conserved protein of unknown function\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"NITINOP_0622 cbpA; curved DNA-binding protein, DnaJ homologue that functions as a co-chaperone of DnaK\tK05516 cbpA; curved DNA-binding protein" }, { "name":"NITINOP_2656 cbpA; Chaperone protein DnaJ\tK05516 cbpA; curved DNA-binding protein" }, { "name":"NITINOP_0513 hscB; Co-chaperone protein HscB (Hsc20)\tK04082 hscB; molecular chaperone HscB" }, { "name":"NITINOP_2541 Protein GrpE (modular protein)\tK03687 GRPE; molecular chaperone GrpE" }, { "name":"NITINOP_0036 putative Heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_0311 Heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_0609 Heat shock protein, Hsp20 family\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_0928 Heat shock protein, Hsp20 family\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_2324 Heat shock protein, Hsp20 family\tK13993 HSP20; HSP20 family protein" }, { "name":"NITINOP_1791 groS; Cpn10 chaperonin GroES, small subunit of GroESL\tK04078 groES; chaperonin GroES" }, { "name":"NITINOP_0368 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1009 htrA; putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_1962 degP; Protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_2660 putative periplasmic serine endoprotease DegP-like\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_3076 degQ; Protease DegQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"NITINOP_0656 ftsH; ATP-dependent zinc metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"NITINOP_2485 ftsH; protease, ATP-dependent zinc-metallo\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"NITINOP_0690 atpB; ATP synthase subunit a 2\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"NITINOP_1388 atpB; ATP synthase subunit a\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"NITINOP_2655 conserved exported protein of unknown function\tK06006 cpxP; periplasmic protein CpxP\/Spy" }, { "name":"NITINOP_0584 putative Hydrogenase nickel incorporation protein HypA\tK04651 hypA; hydrogenase nickel incorporation protein HypA\/HybF" }, { "name":"NITINOP_3304 conserved protein of unknown function, putative chaperone protein\tK23349 dmsD; putative dimethyl sulfoxide reductase chaperone" }, { "name":"NITINOP_0254 ppi; putative peptidyl-prolyl cis-trans isomerase\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]" }, { "name":"NITINOP_2795 ppiB; Peptidyl-prolyl cis-trans isomerase\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]" }, { "name":"NITINOP_2838 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]" }, { "name":"NITINOP_1468 putative Peptidylprolyl isomerase, PpiC-type\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]" }, { "name":"NITINOP_2817 trxA; Thioredoxin\tK03671 TXN; thioredoxin" }, { "name":"NITINOP_0620 trxC; thioredoxin 2\tK03672 trxC; thioredoxin 2 [EC:1.8.1.8]" }, { "name":"NITINOP_1550 grxD; Glutaredoxin\tK07390 grxD; monothiol glutaredoxin" }, { "name":"NITINOP_0389 putative Disulfide oxidoreductase dsbA\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]" }, { "name":"NITINOP_0069 ccmG; Cytochrome c-type biogenesis protein CcmG\tK02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE" } ] }, { "name":"04131 Membrane trafficking [BR:nio04131]", "children":[ { "name":"NITINOP_2491 ndk; multifunctional nucleoside diphosphate kinase and apyrimidinic endonuclease and 3'-phosphodiesterase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"NITINOP_3157 gapA; Glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"NITINOP_1254 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"NITINOP_2630 pykA; Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"NITINOP_0833 conserved exported protein of unknown function\tK20523 SH3YL1; SH3 domain-containing YSC84-like protein 1" } ] }, { "name":"04121 Ubiquitin system [BR:nio04121]", "children":[ { "name":"NITINOP_3289 pup; Prokaryotic ubiquitin-like protein Pup\tK13570 pup; prokaryotic ubiquitin-like protein Pup" } ] }, { "name":"03051 Proteasome [BR:nio03051]", "children":[ { "name":"NITINOP_1620 putative Proteasome, alpha subunit\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]" }, { "name":"NITINOP_3238 prcA; Proteasome subunit alpha\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]" }, { "name":"NITINOP_1619 putative Proteasome, beta subunit\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]" }, { "name":"NITINOP_3239 prcB; Proteasome subunit beta\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]" }, { "name":"NITINOP_1616 Uncharacterized ATPase, AAA family\tK13527 mpa; proteasome-associated ATPase" }, { "name":"NITINOP_3241 arc; Proteasome-associated ATPase\tK13527 mpa; proteasome-associated ATPase" }, { "name":"NITINOP_1621 conserved protein of unknown function\tK13571 pafA; proteasome accessory factor A [EC:6.3.1.19]" }, { "name":"NITINOP_3237 pafA; Pup--protein ligase\tK13571 pafA; proteasome accessory factor A [EC:6.3.1.19]" }, { "name":"NITINOP_1617 dop; Depupylase\tK20814 dop; Pup amidohydrolase [EC:3.5.1.119]" }, { "name":"NITINOP_3240 dop; Depupylase\tK20814 dop; Pup amidohydrolase [EC:3.5.1.119]" } ] }, { "name":"03032 DNA replication proteins [BR:nio03032]", "children":[ { "name":"NITINOP_2046 dcm; Cytosine-specific methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"NITINOP_0049 hupB; HU, DNA-binding transcriptional regulator, beta subunit\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"NITINOP_0763 hup; SPBc2 prophage-derived DNA-binding protein HU 2\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"NITINOP_1138 ihfA; Integration host factor subunit alpha\tK04764 ihfA; integration host factor subunit alpha" }, { "name":"NITINOP_1294 ihfB; integration host factor (IHF), DNA-binding protein, beta subunit\tK05788 ihfB; integration host factor subunit beta" }, { "name":"NITINOP_0993 dnaA; chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"NITINOP_2645 dnaC; Replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]" }, { "name":"NITINOP_0111 dnaG; DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]" }, { "name":"NITINOP_0265 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"NITINOP_2678 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"NITINOP_0992 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"NITINOP_1415 holA; putative DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"NITINOP_2363 holB; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"NITINOP_1079 dnaX; DNA polymerase III, gamma and tau subunits\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"NITINOP_3252 rnhB; Ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]" }, { "name":"NITINOP_0108 rnhC; Ribonuclease\tK03471 rnhC; ribonuclease HIII [EC:3.1.26.4]" }, { "name":"NITINOP_1635 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"NITINOP_2058 ligA; DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" }, { "name":"NITINOP_0990 gyrA; DNA gyrase (type II topoisomerase), subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"NITINOP_0991 gyrB; DNA gyrase, subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" }, { "name":"NITINOP_2081 top6A; Type 2 DNA topoisomerase 6 subunit A\tK03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]" }, { "name":"NITINOP_2080 top6B; Type 2 DNA topoisomerase 6 subunit B\tK03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]" }, { "name":"NITINOP_0082 topA; DNA topoisomerase 1\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]" } ] }, { "name":"03036 Chromosome and associated proteins [BR:nio03036]", "children":[ { "name":"NITINOP_2046 dcm; Cytosine-specific methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"NITINOP_0255 rnc; Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"NITINOP_1642 putative Formimidoyltransferase-cyclodeaminase\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" }, { "name":"NITINOP_0049 hupB; HU, DNA-binding transcriptional regulator, beta subunit\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"NITINOP_0763 hup; SPBc2 prophage-derived DNA-binding protein HU 2\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"NITINOP_1138 ihfA; Integration host factor subunit alpha\tK04764 ihfA; integration host factor subunit alpha" }, { "name":"NITINOP_1294 ihfB; integration host factor (IHF), DNA-binding protein, beta subunit\tK05788 ihfB; integration host factor subunit beta" }, { "name":"NITINOP_0622 cbpA; curved DNA-binding protein, DnaJ homologue that functions as a co-chaperone of DnaK\tK05516 cbpA; curved DNA-binding protein" }, { "name":"NITINOP_2656 cbpA; Chaperone protein DnaJ\tK05516 cbpA; curved DNA-binding protein" }, { "name":"NITINOP_0621 conserved protein of unknown function\tK18997 cbpM; chaperone modulatory protein CbpM" }, { "name":"NITINOP_0993 dnaA; chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"NITINOP_1435 conserved protein of unknown function\tK04047 dps; starvation-inducible DNA-binding protein" }, { "name":"NITINOP_1568 smc; Chromosome partition protein Smc\tK03529 smc; chromosome segregation protein" }, { "name":"NITINOP_1824 scpA; Segregation and condensation protein A\tK05896 scpA; segregation and condensation protein A" }, { "name":"NITINOP_1825 scpB; putative chromosome segregation and condensation protein B\tK06024 scpB; segregation and condensation protein B" }, { "name":"NITINOP_0291 ftsA; ATP-binding cell division protein involved in recruitment of FtsK to Z ring\tK03590 ftsA; cell division protein FtsA" }, { "name":"NITINOP_2375 Cell division protein FtsB homolog (modular protein)\tK05589 ftsB; cell division protein FtsB" }, { "name":"NITINOP_3250 ftsE; transporter subunit: ATP-binding component of ABC superfamily\tK09812 ftsE; cell division transport system ATP-binding protein" }, { "name":"NITINOP_0302 ftsI; Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" }, { "name":"NITINOP_1327 ftsK; DNA translocase FtsK 2\tK03466 ftsK; DNA segregation ATPase FtsK\/SpoIIIE, S-DNA-T family" }, { "name":"NITINOP_0303 conserved exported protein of unknown function\tK03586 ftsL; cell division protein FtsL" }, { "name":"NITINOP_0292 putative Cell division protein FtsQ\tK03589 ftsQ; cell division protein FtsQ" }, { "name":"NITINOP_0297 ftsW; integral membrane protein involved in stabilizing FstZ ring during cell division\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_3249 Cell division protein FtsX\tK09811 ftsX; cell division transport system permease protein" }, { "name":"NITINOP_0290 ftsZ; GTP-binding tubulin-like cell division protein\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"NITINOP_1397 putative Cell division protein ZapA\tK09888 zapA; cell division protein ZapA" }, { "name":"NITINOP_3071 putative N-acetylmuramoyl-L-alanine amidase AmiB\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" }, { "name":"NITINOP_0166 ttgA; Toluene efflux pump periplasmic linker protein TtgA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0321 putative Acriflavine resistance protein acrA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0715 putative RND-type efflux transporter, membrane-fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_1220 putative RND efflux system, membrane fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0285 putative Cell division protein DivIVA\tK04074 divIVA; cell division initiation protein" }, { "name":"NITINOP_0089 mreB; cell wall structural complex MreBCD, actin-like component MreB\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"NITINOP_0088 Cell shape-determining protein MreC\tK03570 mreC; rod shape-determining protein MreC" }, { "name":"NITINOP_0085 mrdB; cell wall shape-determining protein\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0901 soj; Sporulation initiation inhibitor protein Soj\tK03496 parA; chromosome partitioning protein" }, { "name":"NITINOP_0900 parB; putative chromosome-partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"NITINOP_1439 conserved exported protein of unknown function\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"NITINOP_0903 gidA; glucose-inhibited cell-division protein\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme" }, { "name":"NITINOP_0902 putative Ribosomal RNA small subunit methyltransferase G\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]" }, { "name":"NITINOP_1073 trmFO; Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO\tK04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]" }, { "name":"NITINOP_1072 xerC; Tyrosine recombinase XerC\tK03733 xerC; integrase\/recombinase XerC" }, { "name":"NITINOP_1943 xerD; Tyrosine recombinase XerD\tK04763 xerD; integrase\/recombinase XerD" }, { "name":"NITINOP_1964 conserved protein of unknown function\tK03593 mrp; ATP-binding protein involved in chromosome partitioning" }, { "name":"NITINOP_2241 mrp; putative Protein Mrp, ATPase\tK03593 mrp; ATP-binding protein involved in chromosome partitioning" }, { "name":"NITINOP_1466 engB; putative GTP-binding protein EngB\tK03978 engB; GTP-binding protein" } ] }, { "name":"03400 DNA repair and recombination proteins [BR:nio03400]", "children":[ { "name":"NITINOP_1461 ogt; Methylated-DNA-[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]" }, { "name":"NITINOP_1128 phr; Deoxyribodipyrimidine photolyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]" }, { "name":"NITINOP_0354 putative 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]" }, { "name":"NITINOP_2029 mutY; Endonuclease III\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"NITINOP_1639 nth; Endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"NITINOP_2786 nth; Endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"NITINOP_2030 mutT; Mutator MutT protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]" }, { "name":"NITINOP_1239 conserved protein of unknown function\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"NITINOP_1989 udgA; Uracil-DNA glycosylase\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"NITINOP_0162 alkA; DNA-3-methyladenine glycosylase\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"NITINOP_0231 mutM; DNA-formamidopyrimidine glycosylase and DNA-(Apurinic or apyrimidinic site) lyase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"NITINOP_1431 xthA; Exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"NITINOP_3288 recJ; Single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"NITINOP_2058 ligA; DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" }, { "name":"NITINOP_1635 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"NITINOP_1347 uvrA; Excinuclease ABC, subunit A\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"NITINOP_3268 uvrA; UvrABC system protein A\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"NITINOP_3259 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component\tK03702 uvrB; excinuclease ABC subunit B" }, { "name":"NITINOP_1361 uvrC; UvrABC system protein C\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"NITINOP_1711 ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"NITINOP_1722 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"NITINOP_1723 rpoC; RNA polymerase, beta prime subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"NITINOP_1759 rpoA; RNA polymerase, alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"NITINOP_2783 rpoZ; DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]" }, { "name":"NITINOP_1469 mfd; Transcription-repair-coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"NITINOP_0777 mutS; DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS" }, { "name":"NITINOP_3156 mutS; Endonuclease MutS2\tK07456 mutS2; DNA mismatch repair protein MutS2" }, { "name":"NITINOP_1951 mutL; DNA mismatch repair protein MutL\tK03572 mutL; DNA mismatch repair protein MutL" }, { "name":"NITINOP_1401 xseA; Exodeoxyribonuclease 7 large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]" }, { "name":"NITINOP_1402 xseB; Exodeoxyribonuclease 7 small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]" }, { "name":"NITINOP_2678 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"NITINOP_0992 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"NITINOP_1415 holA; putative DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"NITINOP_2363 holB; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"NITINOP_1079 dnaX; DNA polymerase III, gamma and tau subunits\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"NITINOP_0265 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"NITINOP_2527 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA" }, { "name":"NITINOP_1282 ruvA; Holliday junction ATP-dependent DNA helicase RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA" }, { "name":"NITINOP_1284 ruvB; ATP-dependent DNA helicase, component of RuvABC resolvasome\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]" }, { "name":"NITINOP_2769 putative Crossover junction endodeoxyribonuclease RusA\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]" }, { "name":"NITINOP_1104 putative Primosomal protein N\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"NITINOP_2802 radA; DNA repair protein RadA homolog\tK04485 radA; DNA repair protein RadA\/Sms" }, { "name":"NITINOP_1814 recG; ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"NITINOP_2378 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)" }, { "name":"NITINOP_1077 recR; gap repair protein\tK06187 recR; recombination protein RecR" }, { "name":"NITINOP_2816 recN; DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)" }, { "name":"NITINOP_2088 conserved protein of unknown function\tK16899 addB; ATP-dependent helicase\/nuclease subunit B [EC:5.6.2.4 3.1.-.-]" }, { "name":"NITINOP_1013 cas1; CRISPR-associated endonuclease Cas1 1\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"NITINOP_2510 cas4-cas; CRISPR-associated protein Cas4\/endonuclease Cas1 fusion\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"NITINOP_2583 cas1; CRISPR-associated endonuclease Cas1 1\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"NITINOP_0990 gyrA; DNA gyrase (type II topoisomerase), subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"NITINOP_0991 gyrB; DNA gyrase, subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" }, { "name":"NITINOP_0082 topA; DNA topoisomerase 1\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]" }, { "name":"NITINOP_0049 hupB; HU, DNA-binding transcriptional regulator, beta subunit\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"NITINOP_0763 hup; SPBc2 prophage-derived DNA-binding protein HU 2\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"NITINOP_1138 ihfA; Integration host factor subunit alpha\tK04764 ihfA; integration host factor subunit alpha" }, { "name":"NITINOP_1294 ihfB; integration host factor (IHF), DNA-binding protein, beta subunit\tK05788 ihfB; integration host factor subunit beta" }, { "name":"NITINOP_1471 dinB; DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]" }, { "name":"NITINOP_2932 putative Repressor LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]" }, { "name":"NITINOP_3190 lexA; LexA repressor\tK01356 lexA; repressor LexA [EC:3.4.21.88]" }, { "name":"NITINOP_2934 dnaE; DNA polymerase III, alpha subunit\tK14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]" }, { "name":"NITINOP_2528 protein of unknown function\tK03565 recX; regulatory protein" }, { "name":"NITINOP_3245 putative DNA polymerase IV, family X (N-terminal)\tK02347 polX; DNA polymerase (family X)" }, { "name":"NITINOP_2625 putative ATP-dependent DNA helicase Lhr\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]" }, { "name":"NITINOP_0347 Ribonucleoside-diphosphate reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_1994 nrdZ; Ribonucleoside-diphosphate reductase NrdZ\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_2043 nrdJ; Vitamin B12-dependent ribonucleotide reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"NITINOP_0346 Ribonucleoside-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]" } ] }, { "name":"03029 Mitochondrial biogenesis [BR:nio03029]", "children":[ { "name":"NITINOP_1592 putative Quinol-cytochrome c reductase, cytochrome b subunit\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit" }, { "name":"NITINOP_0786 infB; Translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2" }, { "name":"NITINOP_1268 infC; protein chain initiation factor IF-3\tK02520 infC; translation initiation factor IF-3" }, { "name":"NITINOP_2462 tsf; Elongation factor Ts\tK02357 tsf; elongation factor Ts" }, { "name":"NITINOP_1715 tufB; protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"NITINOP_1727 tufB; protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"NITINOP_1726 fusA; protein chain elongation factor EF-G, GTP-binding\tK02355 fusA; elongation factor G" }, { "name":"NITINOP_2661 fusA; Elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"NITINOP_2376 era; GTPase Era\tK03595 era; GTPase" }, { "name":"NITINOP_2495 tyrS; Tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"NITINOP_1413 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"NITINOP_1830 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"NITINOP_3332 argS; Arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"NITINOP_2370 gatA; Glutamyl-tRNA(Gln) amidotransferase subunit A\tK02433 gatA; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]" }, { "name":"NITINOP_2373 gatB; Aspartyl\/glutamyl-tRNA(Asn\/Gln) amidotransferase subunit B\tK02434 gatB; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]" }, { "name":"NITINOP_2368 gatC; Aspartyl\/glutamyl-tRNA(Asn\/Gln) amidotransferase subunit C\tK02435 gatC; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]" }, { "name":"NITINOP_0265 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"NITINOP_3137 putative Outer membrane protein assembly factor YaeT\tK07277 SAM50; outer membrane protein insertion porin family" }, { "name":"NITINOP_0514 dnaK; chaperone Hsp70, co-chaperone with DnaJ\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_2540 dnaK; chaperone Hsp70 in DNA biosynthesis\/cell division\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_2541 Protein GrpE (modular protein)\tK03687 GRPE; molecular chaperone GrpE" }, { "name":"NITINOP_1790 groEL; chaperone Hsp60, peptide-dependent ATPase, heat shock protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"NITINOP_1791 groS; Cpn10 chaperonin GroES, small subunit of GroESL\tK04078 groES; chaperonin GroES" }, { "name":"NITINOP_2539 dnaJ; chaperone Hsp40, co-chaperone with DnaK\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"NITINOP_2621 conserved protein of unknown function\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"NITINOP_0510 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"NITINOP_0513 hscB; Co-chaperone protein HscB (Hsc20)\tK04082 hscB; molecular chaperone HscB" }, { "name":"NITINOP_1550 grxD; Glutaredoxin\tK07390 grxD; monothiol glutaredoxin" }, { "name":"NITINOP_1964 conserved protein of unknown function\tK03593 mrp; ATP-binding protein involved in chromosome partitioning" }, { "name":"NITINOP_2241 mrp; putative Protein Mrp, ATPase\tK03593 mrp; ATP-binding protein involved in chromosome partitioning" }, { "name":"NITINOP_0905 yidC; Membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"NITINOP_1016 putative SCO family protein\tK07152 SCO1; protein SCO1" }, { "name":"NITINOP_1017 Cytochrome oxidase biogenesis protein Sco1\/SenC\/PrrC, putative copper metallochaperone (fragment)\tK07152 SCO1; protein SCO1" } ] } ] }, { "name":"09183 Protein families: signaling and cellular processes", "children":[ { "name":"02000 Transporters [BR:nio02000]", "children":[ { "name":"NITINOP_0476 msbA; Lipid A export ATP-binding\/permease protein MsbA\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"NITINOP_3129 msbA; Lipid A export ATP-binding\/permease protein MsbA\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"NITINOP_3206 apxIB; Toxin RTX-I translocation ATP-binding protein\tK11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB\/CyaB" }, { "name":"NITINOP_3051 msbA; Lipid A export ATP-binding\/permease protein MsbA\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial" }, { "name":"NITINOP_3184 modA; Molybdate ABC transporter, periplasmic binding protein\tK02020 modA; molybdate transport system substrate-binding protein" }, { "name":"NITINOP_3185 modB; Molybdate ABC transporter, permease protein\tK02018 modB; molybdate transport system permease protein" }, { "name":"NITINOP_3186 modC; Molybdate ABC transporter, ATP-binding protein\tK02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]" }, { "name":"NITINOP_1890 fbpA; ABC transporter, periplasmic binding component, Fe3+ transport system\tK02012 afuA; iron(III) transport system substrate-binding protein" }, { "name":"NITINOP_1889 fbpB; ABC transporter, permease component, Fe3+ transport system\tK02011 afuB; iron(III) transport system permease protein" }, { "name":"NITINOP_1888 fbpC; ABC transporter, ATP-binding component, Fe3+ transport system\tK02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]" }, { "name":"NITINOP_2738 putative ABC-type sugar transport system, ATPase component\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]" }, { "name":"NITINOP_2741 putative ABC-type sugar transport system, periplasmic binding component\tK10236 thuE; trehalose\/maltose transport system substrate-binding protein" }, { "name":"NITINOP_2740 putative ABC-type sugar transport system, permease component\tK10237 thuF; trehalose\/maltose transport system permease protein" }, { "name":"NITINOP_2739 putative ABC-type sugar transport system, permease component\tK10238 thuG; trehalose\/maltose transport system permease protein" }, { "name":"NITINOP_0652 putative ABC-type transport system, periplasmic binding component\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"NITINOP_1573 yrbD; putative ABC transporter, periplasmic binding component, ATP-dependent toluene efflux transporter\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"NITINOP_0655 putative ABC-type transport system, permease component\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"NITINOP_1571 yrbE; toluene transporter subunit: membrane component of ABC superfamily\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"NITINOP_0654 putative ABC-type transport system, ATP binding component\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"NITINOP_1572 yrbF; putative ABC transporter, ATPase component, ATP-dependent toluene efflux transporter\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"NITINOP_0651 putative ABC-type transport system, auxiliary component\tK18480 linN; cholesterol transport system auxiliary component" }, { "name":"NITINOP_1574 putative ABC transporter, auxiliary component, ATP-dependent toluene efflux transporter\tK07323 mlaC; phospholipid transport system substrate-binding protein" }, { "name":"NITINOP_1321 putative Phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1322 putative Phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1686 PstS; Strongly similar to phosphate binding protein of ABC-type phosphate transport system\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_2211 putative Phosphate-binding protein PstS\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"NITINOP_1323 putative Phosphate ABC transporter, permease component\tK02037 pstC; phosphate transport system permease protein" }, { "name":"NITINOP_1324 putative Phosphate ABC transporter, permease component 2\tK02038 pstA; phosphate transport system permease protein" }, { "name":"NITINOP_1325 pstB; Phosphate ABC transporter, ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]" }, { "name":"NITINOP_3362 urtA; Urea ABC transporter, urea binding protein UrtA\tK11959 urtA; urea transport system substrate-binding protein" }, { "name":"NITINOP_3361 urtB; Urea ABC transporter, permease protein UrtB\tK11960 urtB; urea transport system permease protein" }, { "name":"NITINOP_3360 urtC; Urea ABC transporter, permease protein UrtC\tK11961 urtC; urea transport system permease protein" }, { "name":"NITINOP_3359 urtD; Urea ABC transporter, ATP-binding protein UrtD\tK11962 urtD; urea transport system ATP-binding protein" }, { "name":"NITINOP_3358 urtE; Urea ABC transporter, ATP-binding protein UrtE\tK11963 urtE; urea transport system ATP-binding protein" }, { "name":"NITINOP_0033 conserved protein of unknown function\tK02030 ABC.PA.S; polar amino acid transport system substrate-binding protein" }, { "name":"NITINOP_1608 ABC-type Fe3+-hydroxamate transport system,periplasmic component\tK02016 ABC.FEV.S; iron complex transport system substrate-binding protein" }, { "name":"NITINOP_1835 ribonuclease HI, degrades RNA of DNA-RNA hybrids (modular protein)\tK02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]" }, { "name":"NITINOP_2546 putative Vitamin B12 import system, periplasmic binding protein BtuF\tK25034 btuF; cobalamin transport system substrate-binding protein" }, { "name":"NITINOP_2547 btuC; Vitamin B12 import system, permease protein BtuC\tK25027 btuC; cobalamin transport system permease protein" }, { "name":"NITINOP_2548 putative Vitamin B12 import system, ATP-binding protein BtuD\tK25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8]" }, { "name":"NITINOP_1188 mntC; Manganese transport system, permease component\tK09819 ABC.MN.P; manganese\/iron transport system permease protein" }, { "name":"NITINOP_1189 mntB; Manganese transport system, ATPase component\tK09820 ABC.MN.A; manganese\/iron transport system ATP-binding protein" }, { "name":"NITINOP_1190 putative Manganese transport system, periplasmic binding component\tK02077 ABC.ZM.S; zinc\/manganese transport system substrate-binding protein" }, { "name":"NITINOP_2568 putative Permease, YjgP\/YjgQ family\tK07091 lptF; lipopolysaccharide export system permease protein" }, { "name":"NITINOP_2567 putative Permease, YjgP\/YjgQ family\tK11720 lptG; lipopolysaccharide export system permease protein" }, { "name":"NITINOP_1764 lptB; putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]" }, { "name":"NITINOP_1701 ABC-type transport system, permease component\tK25151 gldF; gliding motility-associated transport system permease protein" }, { "name":"NITINOP_1702 ABC-type transport system, ATPase component\tK25152 gldA; gliding motility-associated transport system ATP-binding protein" }, { "name":"NITINOP_1700 conserved membrane protein of unknown function\tK25153 gldG; gliding motility-associatede transport system auxiliary component" }, { "name":"NITINOP_0710 ABC transport system, permease component\tK25181 ybhS; drug efflux transport system permease protein" }, { "name":"NITINOP_0711 ybhF; Uncharacterized ABC transporter ATP-binding protein YbhF\tK25182 ybhF; drug efflux transport system ATP-binding protein" }, { "name":"NITINOP_0712 putative Secretion protein HlyD\tK25183 ybhG; membrane fusion protein YbhG" }, { "name":"NITINOP_2073 lolC; Lipoprotein-releasing system, transmembrane protein LolC\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"NITINOP_2072 lolD; outer membrane-specific lipoprotein transporter subunit; ATP-binding component of ABC superfamily\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]" }, { "name":"NITINOP_0072 putative Heme exporter protein CcmD\tK02196 ccmD; heme exporter protein D" }, { "name":"NITINOP_0073 ccmC; Heme exporter protein CcmC\tK02195 ccmC; heme exporter protein C" }, { "name":"NITINOP_0074 ccmB; Heme exporter protein CcmB\tK02194 ccmB; heme exporter protein B" }, { "name":"NITINOP_0075 ccmA; Heme exporter protein CcmA\tK02193 ccmA; heme exporter protein A [EC:7.6.2.5]" }, { "name":"NITINOP_3249 Cell division protein FtsX\tK09811 ftsX; cell division transport system permease protein" }, { "name":"NITINOP_3250 ftsE; transporter subunit: ATP-binding component of ABC superfamily\tK09812 ftsE; cell division transport system ATP-binding protein" }, { "name":"NITINOP_0709 yhhJ; ABC transport system, permease component\tK01992 ABC-2.P; ABC-2 type transport system permease protein" }, { "name":"NITINOP_1216 putative Daunorubicin resistance ABC transporter, membrane protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein" }, { "name":"NITINOP_1969 putative ABC-2 type transport system, ATP-binding and permease component\tK01992 ABC-2.P; ABC-2 type transport system permease protein" }, { "name":"NITINOP_3032 ABC-type multidrug transport system, permease component\tK01992 ABC-2.P; ABC-2 type transport system permease protein" }, { "name":"NITINOP_1217 drrA; Daunorubicin\/doxorubicin resistance ATP-binding protein DrrA\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein" }, { "name":"NITINOP_1968 ABC-type transport system, ATP-binding component\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein" }, { "name":"NITINOP_2650 conserved protein of unknown function\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein" }, { "name":"NITINOP_3031 ABC-type multidrug transport system, ATPase component\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein" }, { "name":"NITINOP_0572 putative ABC-type transport system, permease component\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"NITINOP_0889 putative Uncharacterized ABC-type transport system, permease component YbbP\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"NITINOP_1876 conserved membrane protein of unknown function\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"NITINOP_1877 ABC transporter permease protein\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"NITINOP_2455 macC; putative ABC transporter, permease component, Macrolide export permease protein\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"NITINOP_2761 putative ABC transporter, permease component\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"NITINOP_0888 ybbA; putative transporter subunit: ATP-binding component of ABC superfamily\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"NITINOP_1878 yvrO; Uncharacterized ABC transporter ATP-binding protein YvrO\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"NITINOP_2764 conserved protein of unknown function\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"NITINOP_2246 Rh50; Ammonium transporter Rh50\tK06580 SLC42A; ammonium transporter Rh" }, { "name":"NITINOP_2720 putative Multidrug resistance protein NorM\tK26939 norM; MATE family, multidrug efflux pump" }, { "name":"NITINOP_2839 putative Sugar transporter of the major facilitator superfamily\tK03535 gudP; MFS transporter, ACS family, glucarate transporter" }, { "name":"NITINOP_2041 ampG; muropeptide transporter\tK08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG" }, { "name":"NITINOP_3175 mscL; mechanosensitive channel\tK03282 mscL; large conductance mechanosensitive channel" }, { "name":"NITINOP_0697 Small-conductance mechanosensitive channel\tK22044 ybiO; moderate conductance mechanosensitive channel" }, { "name":"NITINOP_2377 mgtE; Magnesium transporter MgtE\tK06213 mgtE; magnesium transporter" }, { "name":"NITINOP_2279 motA; Flagellar motor protein MotA\tK02556 motA; chemotaxis protein MotA" }, { "name":"NITINOP_2280 motB; Flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" }, { "name":"NITINOP_1887 exbB; Biopolymer transport protein ExbB\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"NITINOP_1679 Biopolymer transport protein ExbD\/TolR\tK03559 exbD; biopolymer transport protein ExbD" }, { "name":"NITINOP_1886 exbD; Biopolymer transport protein ExbD\tK03559 exbD; biopolymer transport protein ExbD" }, { "name":"NITINOP_1678 MotA\/TolQ\/ExbB proton channel\tK03562 tolQ; biopolymer transport protein TolQ" }, { "name":"NITINOP_1944 MotA\/TolQ\/ExbB proton channel family protein\tK03562 tolQ; biopolymer transport protein TolQ" }, { "name":"NITINOP_1945 exbD; Biopolymer transport protein ExbD\tK03560 tolR; biopolymer transport protein TolR" }, { "name":"NITINOP_1839 putative Fluoride ion transporter CrcB\tK06199 crcB; fluoride exporter" }, { "name":"NITINOP_1061 merT; Mercuric transport protein\tK08363 merT; mercuric ion transport protein" }, { "name":"NITINOP_2975 merT; Mercuric transport protein\tK08363 merT; mercuric ion transport protein" }, { "name":"NITINOP_1062 exported protein of unknown function\tK08364 merP; periplasmic mercuric ion binding protein" }, { "name":"NITINOP_2974 merP; Mercuric transport protein periplasmic component\tK08364 merP; periplasmic mercuric ion binding protein" }, { "name":"NITINOP_2057 conserved membrane protein of unknown function\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" }, { "name":"NITINOP_1360 putative long-chain fatty acid outer membrane transporter\tK06076 fadL; long-chain fatty acid transport protein" }, { "name":"NITINOP_1884 putative Iron(III) dicitrate transport protein FecA\tK16091 fecA; Fe(3+) dicitrate transport protein" }, { "name":"NITINOP_2550 putative Vitamin B12 transporter BtuB\tK16092 btuB; vitamin B12 transporter" }, { "name":"NITINOP_1868 putative TonB-dependent receptor plug\tK16087 TC.FEV.OM3; hemoglobin\/transferrin\/lactoferrin receptor protein" }, { "name":"NITINOP_1937 putative TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"NITINOP_2328 putative Heavy metal efflux system, outer membrane lipoprotein\tK15725 czcC; outer membrane protein, heavy metal efflux system" }, { "name":"NITINOP_2964 putative Cation efflux system protein CzcC\tK15725 czcC; outer membrane protein, heavy metal efflux system" }, { "name":"NITINOP_3056 putative Outer membrane protein TolC\tK15725 czcC; outer membrane protein, heavy metal efflux system" }, { "name":"NITINOP_0373 putative Similar to heavy metal efflux pump protein CzcC\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"NITINOP_2958 conserved exported protein of unknown function\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"NITINOP_2971 putative Similar to heavy metal efflux pump protein CzcC\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"NITINOP_0013 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0713 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3265 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0164 oprM; Outer membrane protein OprM\tK18139 oprM; outer membrane protein, multidrug efflux system" }, { "name":"NITINOP_0409 exported protein of unknown function\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"NITINOP_2387 Putative Polysaccharide export protein (fragment)\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"NITINOP_2388 putative Polysaccharide export protein\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"NITINOP_3137 putative Outer membrane protein assembly factor YaeT\tK07277 SAM50; outer membrane protein insertion porin family" }, { "name":"NITINOP_1561 conserved protein of unknown function\tK05807 bamD; outer membrane protein assembly factor BamD" }, { "name":"NITINOP_0593 exported protein of unknown function\tK09800 tamB; translocation and assembly module TamB" }, { "name":"NITINOP_1763 conserved exported protein of unknown function\tK09774 lptA; lipopolysaccharide export system protein LptA" }, { "name":"NITINOP_2818 conserved exported protein of unknown function\tK04744 lptD; LPS-assembly protein" }, { "name":"NITINOP_1172 Urea carboxylase-related amino acid permease\tK28029 UGA4; amino acid or GABA permease" }, { "name":"NITINOP_2360 zitB; Zinc transporter ZitB\tK16264 czcD; cobalt-zinc-cadmium efflux system protein" }, { "name":"NITINOP_0385 czcA; Cation efflux system protein CzcA\tK15726 czcA; heavy metal efflux system protein" }, { "name":"NITINOP_2330 czcA; Cation efflux system protein CzcA\tK15726 czcA; heavy metal efflux system protein" }, { "name":"NITINOP_2962 czcA; Cation efflux system protein CzcA\tK15726 czcA; heavy metal efflux system protein" }, { "name":"NITINOP_3054 putative Heavy metal efflux pump, CzcA family, Acriflavine resistance protein B\tK15726 czcA; heavy metal efflux system protein" }, { "name":"NITINOP_0371 cusA; copper\/silver efflux system, membrane component\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"NITINOP_2956 cusA; copper\/silver efflux system, membrane component\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"NITINOP_2969 cusA; copper\/silver efflux system, membrane component\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"NITINOP_0165 acrB; multidrug efflux system protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0322 acrB; Acriflavin resistance protein acrB\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0714 putative RND-type efflux transporter, transmembrane pump\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_1221 putative RND efflux system, multidrug resistance protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_1199 Ca2+\/Na+ antiporter\tK07301 yrbG; cation:H+ antiporter" }, { "name":"NITINOP_0662 nhaA; Na(+)\/H(+) antiporter NhaA\tK03313 nhaA; Na+:H+ antiporter, NhaA family" }, { "name":"NITINOP_0700 putative Potassium\/proton antiporter\tK11105 cvrA; potassium\/hydrogen antiporter" }, { "name":"NITINOP_0698 nhaP; Na(+)\/H(+) antiporter NhaP\tK03316 nhaP; Na+:H+ antiporter" }, { "name":"NITINOP_1646 putative Glutathione-regulated potassium-efflux system\tK26735 KEA4_5_6; K+:H+ antiporter" }, { "name":"NITINOP_1697 putative TRAP dicarboxylate transporter-DctP subunit\tK11688 dctP; TRAP-type transport system periplasmic protein" }, { "name":"NITINOP_1698 TRAP dicarboxylate transporter-DctM subunit\tK21393 dctQM; TRAP-type transport system permease protein" }, { "name":"NITINOP_3189 Sodium Bile acid symporter family protein\tK03325 ACR3; arsenite transporter" }, { "name":"NITINOP_1460 mviN; Protein MurJ homolog\tK03980 murJ; putative peptidoglycan lipid II flippase" }, { "name":"NITINOP_1428 oliA; Oligopeptide transporter\tK28868 K28868; oligopeptide transporter family protein" }, { "name":"NITINOP_0814 putative AEC-type transporter\tK24180 mleP; malate permease and related proteins" }, { "name":"NITINOP_0650 conserved membrane protein of unknown function\tK22736 VIT; vacuolar iron transporter family protein" }, { "name":"NITINOP_0297 ftsW; integral membrane protein involved in stabilizing FstZ ring during cell division\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"NITINOP_0308 cstA; Carbon starvation protein A\tK06200 cstA; carbon starvation protein" }, { "name":"NITINOP_1680 protein of unknown function\tK03832 tonB; periplasmic protein TonB" }, { "name":"NITINOP_1885 putative TonB protein\tK03832 tonB; periplasmic protein TonB" }, { "name":"NITINOP_0745 Peptidoglycan-associated lipoprotein (modular protein)\tK03640 pal; peptidoglycan-associated lipoprotein" }, { "name":"NITINOP_1314 pal; Peptidoglycan-associated lipoprotein Pal (Modular protein)\tK03640 pal; peptidoglycan-associated lipoprotein" }, { "name":"NITINOP_1948 pal; Peptidoglycan-associated lipoprotein Pal (Modular protein)\tK03640 pal; peptidoglycan-associated lipoprotein" }, { "name":"NITINOP_2314 putative Peptidoglycan-associated lipoprotein\tK03640 pal; peptidoglycan-associated lipoprotein" }, { "name":"NITINOP_1163 conserved exported protein of unknown function\tK03641 tolB; TolB protein" }, { "name":"NITINOP_1947 TolB protein, periplasmic protein involved in the tonb-independent uptake of group A colicins\tK03641 tolB; TolB protein" }, { "name":"NITINOP_3290 hppA; K(+)-insensitive pyrophosphate-energized proton pump\tK15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]" }, { "name":"NITINOP_1560 ccdA; Cytochrome c biogenesis protein CcdA\tK06196 ccdA; cytochrome c-type biogenesis protein" }, { "name":"NITINOP_0879 nxrA; Nitrite oxidoreductase, alpha subunit\tK00370 narG; nitrate reductase \/ nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]" }, { "name":"NITINOP_0878 nxrB; Nitrate oxidoreductase, beta subunit\tK00371 narH; nitrate reductase \/ nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]" }, { "name":"NITINOP_0386 putative Heavy metal efflux system, membrane fusion protein\tK15727 czcB; membrane fusion protein, heavy metal efflux system" }, { "name":"NITINOP_2329 putative Heavy metal efflux system, membrane fusion protein\tK15727 czcB; membrane fusion protein, heavy metal efflux system" }, { "name":"NITINOP_2963 putative Efflux transporter, RND family, MFP subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system" }, { "name":"NITINOP_3055 putative Acriflavine resistance protein A\tK15727 czcB; membrane fusion protein, heavy metal efflux system" }, { "name":"NITINOP_0372 Efflux transporter, RND family, MFP subunit (modular protein)\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"NITINOP_2957 conserved exported protein of unknown function\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"NITINOP_2970 protein of unknown function\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"NITINOP_3205 putative Type I secretion membrane fusion protein HlyD\tK11003 hlyD; membrane fusion protein, hemolysin D" }, { "name":"NITINOP_0166 ttgA; Toluene efflux pump periplasmic linker protein TtgA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0321 putative Acriflavine resistance protein acrA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0715 putative RND-type efflux transporter, membrane-fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_1220 putative RND efflux system, membrane fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_2390 putative Lipopolysaccharide biosynthesis protein\tK16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]" }, { "name":"NITINOP_0406 putative Exopolysaccharide biosynthesis related tyrosine-protein kinase\tK00903 epsB; protein-tyrosine kinase [EC:2.7.10.3]" }, { "name":"NITINOP_0407 putative Lipopolysaccharide biosynthesis protein\tK25590 epsF; protein tyrosine kinase modulator" }, { "name":"NITINOP_0070 ccmF; Cytochrome c-type biogenesis protein CcmF\tK02198 ccmF; cytochrome c-type biogenesis protein CcmF" }, { "name":"NITINOP_1858 putative Copper resistance protein CopC\tK07156 copC; copper resistance protein C" } ] }, { "name":"02044 Secretion system [BR:nio02044]", "children":[ { "name":"NITINOP_3206 apxIB; Toxin RTX-I translocation ATP-binding protein\tK11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB\/CyaB" }, { "name":"NITINOP_3205 putative Type I secretion membrane fusion protein HlyD\tK11003 hlyD; membrane fusion protein, hemolysin D" }, { "name":"NITINOP_0013 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0713 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3265 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_1675 exported protein of unknown function\tK02452 gspC; general secretion pathway protein C" }, { "name":"NITINOP_2307 protein of unknown function\tK02452 gspC; general secretion pathway protein C" }, { "name":"NITINOP_0218 putative general secretion pathway protein D\tK02453 gspD; general secretion pathway protein D" }, { "name":"NITINOP_2306 gspE; general secretory pathway component, cryptic\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"NITINOP_2305 gspF; General secretion pathway protein F\tK02455 gspF; general secretion pathway protein F" }, { "name":"NITINOP_2304 gspG; pseudopilin, cryptic, general secretion pathway\tK02456 gspG; general secretion pathway protein G" }, { "name":"NITINOP_2303 exported protein of unknown function\tK02457 gspH; general secretion pathway protein H" }, { "name":"NITINOP_2302 putative general secretion pathway protein I\tK02458 gspI; general secretion pathway protein I" }, { "name":"NITINOP_2301 protein of unknown function\tK02459 gspJ; general secretion pathway protein J" }, { "name":"NITINOP_2297 putative general secretion pathway protein K\tK02460 gspK; general secretion pathway protein K" }, { "name":"NITINOP_2299 protein of unknown function\tK02461 gspL; general secretion pathway protein L" }, { "name":"NITINOP_2298 protein of unknown function\tK02462 gspM; general secretion pathway protein M" }, { "name":"NITINOP_1145 pilD; Type 4 prepilin-like proteins leader peptide-processing enzyme\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"NITINOP_2648 putative Type IV pilin PilA\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"NITINOP_0281 tapC; Type IV pilus assembly protein TapC\tK02653 pilC; type IV pilus assembly protein PilC" }, { "name":"NITINOP_2559 putative Methyl-accepting chemotaxis protein\tK02660 pilJ; twitching motility protein PilJ" }, { "name":"NITINOP_1768 pilM; Type IV pilus biogenesis protein PilM\tK02662 pilM; type IV pilus assembly protein PilM" }, { "name":"NITINOP_1769 putative Type IV pilus biogenesis protein PilN\tK02663 pilN; type IV pilus assembly protein PilN" }, { "name":"NITINOP_1770 putative Type IV pilus biogenesis protein PilO\tK02664 pilO; type IV pilus assembly protein PilO" }, { "name":"NITINOP_1771 putative Type IV pilus assembly protein PilP\tK02665 pilP; type IV pilus assembly protein PilP" }, { "name":"NITINOP_1772 putative Type IV pili biogenesis protein PilQ\tK02666 pilQ; type IV pilus assembly protein PilQ" }, { "name":"NITINOP_0081 pilT; Twitching mobility protein\tK02669 pilT; twitching motility protein PilT" }, { "name":"NITINOP_2637 pilT; twitching motility protein\tK02669 pilT; twitching motility protein PilT" }, { "name":"NITINOP_2636 pilT; Twitching mobility protein\tK02670 pilU; twitching motility protein PilU" }, { "name":"NITINOP_1152 putative Type IV pilus assembly protein PilV\tK02671 pilV; type IV pilus assembly protein PilV" }, { "name":"NITINOP_1153 putative Type IV pilus assembly protein PilW\tK02672 pilW; type IV pilus assembly protein PilW" }, { "name":"NITINOP_1157 putative Type IV pilus assembly protein PilY1\tK02674 pilY1; type IV pilus assembly protein PilY1" }, { "name":"NITINOP_0823 exported protein of unknown function\tK02279 cpaB; pilus assembly protein CpaB" }, { "name":"NITINOP_0824 putative Pilus assembly protein CpaC\tK02280 cpaC; pilus assembly protein CpaC" }, { "name":"NITINOP_2348 Response regulator receiver protein\tK02282 cpaE; pilus assembly protein CpaE" }, { "name":"NITINOP_0829 cpaF; Pilus assembly ATPase CpaF\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]" }, { "name":"NITINOP_2349 Type II secretion system protein E\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]" }, { "name":"NITINOP_0830 membrane protein of unknown function\tK12510 tadB; tight adherence protein B" }, { "name":"NITINOP_2350 putative Type II secretion system protein\tK12510 tadB; tight adherence protein B" }, { "name":"NITINOP_0831 putative Pilus assembly protein TadC\tK12511 tadC; tight adherence protein C" }, { "name":"NITINOP_2351 Type II secretion system protein\tK12511 tadC; tight adherence protein C" }, { "name":"NITINOP_0826 conserved protein of unknown function\tK12513 tadE; tight adherence protein E" }, { "name":"NITINOP_0822 protein of unknown function\tK02651 flp; pilus assembly protein Flp\/PilA" }, { "name":"NITINOP_2342 conserved protein of unknown function\tK02651 flp; pilus assembly protein Flp\/PilA" }, { "name":"NITINOP_0286 conserved protein of unknown function\tK02221 yggT; YggT family protein" }, { "name":"NITINOP_2494 conserved protein of unknown function\tK02237 comEA; competence protein ComEA" }, { "name":"NITINOP_2489 putative Competence protein ComEC\/Rec2 related protein\tK02238 comEC; competence protein ComEC" }, { "name":"NITINOP_2145 flhA; putative flagellar export pore protein\tK02400 flhA; flagellar biosynthesis protein FlhA" }, { "name":"NITINOP_2144 flhB; Flagellar biosynthetic protein FlhB, export component\tK02401 flhB; flagellar biosynthesis protein FlhB" }, { "name":"NITINOP_2127 fliF; Flagellar M-ring protein\tK02409 fliF; flagellar M-ring protein FliF" }, { "name":"NITINOP_2129 putative Flagellar biosynthesis protein FliH with response regulator receiver domain (Modular protein)\tK02411 fliH; flagellar assembly protein FliH" }, { "name":"NITINOP_2130 fliI; flagellum-specific ATP synthase\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]" }, { "name":"NITINOP_2139 fliN; flagellar motor switching and energizing component\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"NITINOP_2140 putative Flagellar biosynthetic protein FliO, export component\tK02418 fliO; flagellar protein FliO\/FliZ" }, { "name":"NITINOP_2141 fliP; flagellar biosynthesis protein\tK02419 fliP; flagellar biosynthesis protein FliP" }, { "name":"NITINOP_2142 fliQ; flagellar biosynthesis protein\tK02420 fliQ; flagellar biosynthesis protein FliQ" }, { "name":"NITINOP_2143 fliR; Flagellar biosynthetic protein fliR\tK02421 fliR; flagellar biosynthesis protein FliR" }, { "name":"NITINOP_2978 conserved protein of unknown function\tK03197 virB2; type IV secretion system protein VirB2" }, { "name":"NITINOP_2979 virB; Type IV secretion system protein virB3\tK03198 virB3; type IV secretion system protein VirB3" }, { "name":"NITINOP_2980 virB; Type IV secretion system protein virB4\tK03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]" }, { "name":"NITINOP_2982 P-type DNA transfer protein VirB5\tK03200 virB5; type IV secretion system protein VirB5" }, { "name":"NITINOP_2981 conserved membrane protein of unknown function\tK03201 virB6; type IV secretion system protein VirB6" }, { "name":"NITINOP_2983 conserved protein of unknown function\tK03203 virB8; type IV secretion system protein VirB8" }, { "name":"NITINOP_2985 conserved exported protein of unknown function\tK03204 virB9; type IV secretion system protein VirB9" }, { "name":"NITINOP_2986 conserved protein of unknown function\tK03195 virB10; type IV secretion system protein VirB10" }, { "name":"NITINOP_2987 virB; Type IV secretion system protein VirB11\tK03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]" }, { "name":"NITINOP_2988 conserved exported protein of unknown function\tK03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]" }, { "name":"NITINOP_1442 Type VI secretion system effector, Hcp1 family\tK11903 hcp; type VI secretion system secreted protein Hcp" }, { "name":"NITINOP_0474 secA; preprotein translocase subunit, ATPase\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"NITINOP_3329 secD; Protein translocase subunit SecD\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"NITINOP_1717 secE; Protein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"NITINOP_3328 secF; Protein translocase subunit SecF\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"NITINOP_3160 secG; Preprotein translocase, membrane subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"NITINOP_1751 secY; preprotein translocase membrane subunit\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"NITINOP_3257 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"NITINOP_1161 ftsY; Signal recognition particle receptor FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"NITINOP_3330 conserved protein of unknown function\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"NITINOP_0905 yidC; Membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"NITINOP_0895 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_0896 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_3299 tatA; Sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"NITINOP_1963 tatC; Sec-independent protein translocase protein TatC\tK03118 tatC; sec-independent protein translocase protein TatC" }, { "name":"NITINOP_2797 tatC; Sec-independent protein translocase protein TatC\tK03118 tatC; sec-independent protein translocase protein TatC" } ] }, { "name":"02042 Bacterial toxins [BR:nio02042]", "children":[ { "name":"NITINOP_2057 conserved membrane protein of unknown function\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" } ] }, { "name":"02022 Two-component system [BR:nio02022]", "children":[ { "name":"NITINOP_1564 putative Phosphate regulon sensor histidine kinase PhoR\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]" }, { "name":"NITINOP_1565 phoB; DNA-binding response regulator in two-component regulatory system with PhoR (or CreC)\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP" }, { "name":"NITINOP_1672 phoP; Alkaline phosphatase synthesis transcriptional regulatory protein PhoP\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP" }, { "name":"NITINOP_1687 putative Phosphate regulon transcriptional regulatory protein PhoB\tK07776 regX3; two-component system, OmpR family, response regulator RegX3" }, { "name":"NITINOP_1506 kdpD; fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein; sensory histidine kinase\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]" }, { "name":"NITINOP_1507 kdpE; DNA-binding response regulator in two-component regulatory system with KdpD\tK07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE" }, { "name":"NITINOP_1100 devR; Transcriptional regulatory protein DevR (DosR)\tK07695 devR; two-component system, NarL family, response regulator DevR" }, { "name":"NITINOP_1356 putative NarL family two-component system response regulator\tK07695 devR; two-component system, NarL family, response regulator DevR" }, { "name":"NITINOP_0020 Response regulator, CheY like\tK02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F" }, { "name":"NITINOP_1541 spo0F; Sporulation initiation phosphotransferase F\tK02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F" }, { "name":"NITINOP_2339 putative Histidine kinase\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]" }, { "name":"NITINOP_2340 Two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator" }, { "name":"NITINOP_1270 conserved protein of unknown function\tK07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG" }, { "name":"NITINOP_2230 Sensor histidine kinase\tK13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]" }, { "name":"NITINOP_2231 ntrX; Nitrogen assimilation regulatory protein NtrX\tK13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX" }, { "name":"NITINOP_0732 Sensory sigma-54 dependent transcriptional regulator\tK07713 zraR; two-component system, NtrC family, response regulator HydG" }, { "name":"NITINOP_3149 zraR; Transcriptional regulatory protein ZraR\tK07713 zraR; two-component system, NtrC family, response regulator HydG" }, { "name":"NITINOP_1479 Sigma-54 dependent transcriptional regulator\tK07714 atoC; two-component system, NtrC family, response regulator AtoC" }, { "name":"NITINOP_2814 atoC; Acetoacetate metabolism regulatory protein AtoC\tK07714 atoC; two-component system, NtrC family, response regulator AtoC" }, { "name":"NITINOP_3326 atoC; Acetoacetate metabolism regulatory protein AtoC\tK07714 atoC; two-component system, NtrC family, response regulator AtoC" }, { "name":"NITINOP_0280 putative Sensor protein PilS\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"NITINOP_0279 atoC; fused response regulator of ato opeon, in two-component system with AtoS: response regulator; sigma54 interaction protein\tK02667 pilR; two-component system, NtrC family, response regulator PilR" }, { "name":"NITINOP_2114 putative Sensor histidine kinase\tK07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]" }, { "name":"NITINOP_2116 yfhA; putative DNA-binding response regulator in two-component system\tK07715 glrR; two-component system, NtrC family, response regulator GlrR" }, { "name":"NITINOP_1547 putative Histidine kinase\tK02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]" }, { "name":"NITINOP_2284 cheA; fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase; signal sensing protein\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]" }, { "name":"NITINOP_1102 Signal transduction response regulator, receiver domain\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2277 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2283 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2292 cheB; fused chemotaxis regulator; protein-glutamate methylesterase in two-component regulatory system with CheA\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]" }, { "name":"NITINOP_2560 putative Histidine kinase\tK06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase\/response regulator)" }, { "name":"NITINOP_0183 Putative Hybrid sensor histidine kinase (fragment)\tK13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]" }, { "name":"NITINOP_1121 putative Hybrid histidine kinase\tK13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]" }, { "name":"NITINOP_1972 putative Response Regulator\tK13589 cpdR; two-component system, cell cycle response regulator CpdR" } ] }, { "name":"02035 Bacterial motility proteins [BR:nio02035]", "children":[ { "name":"NITINOP_2284 cheA; fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase; signal sensing protein\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]" }, { "name":"NITINOP_2286 cheW; purine-binding chemotaxis protein\tK03408 cheW; purine-binding chemotaxis protein CheW" }, { "name":"NITINOP_2558 protein of unknown function\tK03408 cheW; purine-binding chemotaxis protein CheW" }, { "name":"NITINOP_2291 cheD; putative chemoreceptor glutamine deamidase CheD\tK03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]" }, { "name":"NITINOP_2290 cheR; chemotaxis regulator, protein-glutamate methyltransferase\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]" }, { "name":"NITINOP_2292 cheB; fused chemotaxis regulator; protein-glutamate methylesterase in two-component regulatory system with CheA\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]" }, { "name":"NITINOP_1102 Signal transduction response regulator, receiver domain\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2277 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2283 cheY; chemotaxis regulator transmitting signal to flagellar motor component\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY" }, { "name":"NITINOP_2278 putative Chemotaxis regulator CheZ\tK03414 cheZ; chemotaxis protein CheZ" }, { "name":"NITINOP_2287 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_2288 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_3387 putative Methyl-accepting chemotaxis protein\tK03406 mcp; methyl-accepting chemotaxis protein" }, { "name":"NITINOP_2129 putative Flagellar biosynthesis protein FliH with response regulator receiver domain (Modular protein)\tK02411 fliH; flagellar assembly protein FliH" }, { "name":"NITINOP_2130 fliI; flagellum-specific ATP synthase\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]" }, { "name":"NITINOP_2131 conserved protein of unknown function\tK02413 fliJ; flagellar protein FliJ" }, { "name":"NITINOP_2140 putative Flagellar biosynthetic protein FliO, export component\tK02418 fliO; flagellar protein FliO\/FliZ" }, { "name":"NITINOP_2141 fliP; flagellar biosynthesis protein\tK02419 fliP; flagellar biosynthesis protein FliP" }, { "name":"NITINOP_2142 fliQ; flagellar biosynthesis protein\tK02420 fliQ; flagellar biosynthesis protein FliQ" }, { "name":"NITINOP_2143 fliR; Flagellar biosynthetic protein fliR\tK02421 fliR; flagellar biosynthesis protein FliR" }, { "name":"NITINOP_2145 flhA; putative flagellar export pore protein\tK02400 flhA; flagellar biosynthesis protein FlhA" }, { "name":"NITINOP_2144 flhB; Flagellar biosynthetic protein FlhB, export component\tK02401 flhB; flagellar biosynthesis protein FlhB" }, { "name":"NITINOP_2128 fliG; flagellar motor switching and energizing component\tK02410 fliG; flagellar motor switch protein FliG" }, { "name":"NITINOP_2138 fliM; Flagellar motor switch protein FliM\tK02416 fliM; flagellar motor switch protein FliM" }, { "name":"NITINOP_2139 fliN; flagellar motor switching and energizing component\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"NITINOP_2127 fliF; Flagellar M-ring protein\tK02409 fliF; flagellar M-ring protein FliF" }, { "name":"NITINOP_2153 flgI; Flagellar P-ring protein\tK02394 flgI; flagellar P-ring protein FlgI" }, { "name":"NITINOP_2151 putative Flagella basal body P-ring formation protein FlgA\tK02386 flgA; flagellar basal body P-ring formation protein FlgA" }, { "name":"NITINOP_2152 flgH; Flagellar L-ring protein\tK02393 flgH; flagellar L-ring protein FlgH" }, { "name":"NITINOP_2137 fliL; Flagellar basal body-associated protein FliL\tK02415 fliL; flagellar protein FliL" }, { "name":"NITINOP_2126 putative Flagellar hook-basal body complex protein FliE\tK02408 fliE; flagellar hook-basal body complex protein FliE" }, { "name":"NITINOP_2133 protein of unknown function\tK02414 fliK; flagellar hook-length control protein FliK" }, { "name":"NITINOP_2124 flgB; Flagellar basal body rod protein FlgB\tK02387 flgB; flagellar basal-body rod protein FlgB" }, { "name":"NITINOP_2125 flgC; flagellar component of cell-proximal portion of basal-body rod\tK02388 flgC; flagellar basal-body rod protein FlgC" }, { "name":"NITINOP_2134 putative Flagellar hook capping protein\tK02389 flgD; flagellar basal-body rod modification protein FlgD" }, { "name":"NITINOP_2149 flgF; Flagellar basal-body rod protein FlgF\tK02391 flgF; flagellar basal-body rod protein FlgF" }, { "name":"NITINOP_2150 flgG; flagellar component of cell-distal portion of basal-body rod\tK02392 flgG; flagellar basal-body rod protein FlgG" }, { "name":"NITINOP_2154 protein of unknown function\tK02395 flgJ; peptidoglycan hydrolase FlgJ" }, { "name":"NITINOP_2135 putative Flagellar hook protein FlgE\tK02390 flgE; flagellar hook protein FlgE" }, { "name":"NITINOP_2157 protein of unknown function\tK02396 flgK; flagellar hook-associated protein 1" }, { "name":"NITINOP_2158 protein of unknown function\tK02397 flgL; flagellar hook-associated protein 3 FlgL" }, { "name":"NITINOP_2268 hag; Flagellin\tK02406 fliC; flagellin" }, { "name":"NITINOP_2270 putative Flagellar capping protein FliD\tK02407 fliD; flagellar hook-associated protein 2" }, { "name":"NITINOP_2271 fliS; Flagellin-specific chaperone FliS\tK02422 fliS; flagellar secretion chaperone FliS" }, { "name":"NITINOP_2148 fliA; RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" }, { "name":"NITINOP_2279 motA; Flagellar motor protein MotA\tK02556 motA; chemotaxis protein MotA" }, { "name":"NITINOP_2280 motB; Flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" }, { "name":"NITINOP_2160 fliW; Flagellar assembly factor FliW\tK13626 fliW; flagellar assembly factor FliW" }, { "name":"NITINOP_2155 flgM; Anti-sigma 28 factor FlgM\tK02398 flgM; negative regulator of flagellin synthesis FlgM" }, { "name":"NITINOP_2269 protein of unknown function\tK06603 flaG; flagellar protein FlaG" }, { "name":"NITINOP_2146 putative Flagellar biosynthetic protein FlhF, GTP binding\tK02404 flhF; flagellar biosynthesis protein FlhF" }, { "name":"NITINOP_2147 fleN; Site-determining protein\tK04562 flhG; flagellar biosynthesis protein FlhG" }, { "name":"NITINOP_3246 putative Septum site-determining protein MinD\tK04562 flhG; flagellar biosynthesis protein FlhG" }, { "name":"NITINOP_2559 putative Methyl-accepting chemotaxis protein\tK02660 pilJ; twitching motility protein PilJ" }, { "name":"NITINOP_2560 putative Histidine kinase\tK06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase\/response regulator)" }, { "name":"NITINOP_0279 atoC; fused response regulator of ato opeon, in two-component system with AtoS: response regulator; sigma54 interaction protein\tK02667 pilR; two-component system, NtrC family, response regulator PilR" }, { "name":"NITINOP_0280 putative Sensor protein PilS\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"NITINOP_0081 pilT; Twitching mobility protein\tK02669 pilT; twitching motility protein PilT" }, { "name":"NITINOP_2637 pilT; twitching motility protein\tK02669 pilT; twitching motility protein PilT" }, { "name":"NITINOP_2636 pilT; Twitching mobility protein\tK02670 pilU; twitching motility protein PilU" }, { "name":"NITINOP_2648 putative Type IV pilin PilA\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"NITINOP_0281 tapC; Type IV pilus assembly protein TapC\tK02653 pilC; type IV pilus assembly protein PilC" }, { "name":"NITINOP_1145 pilD; Type 4 prepilin-like proteins leader peptide-processing enzyme\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"NITINOP_1772 putative Type IV pili biogenesis protein PilQ\tK02666 pilQ; type IV pilus assembly protein PilQ" }, { "name":"NITINOP_1771 putative Type IV pilus assembly protein PilP\tK02665 pilP; type IV pilus assembly protein PilP" }, { "name":"NITINOP_1770 putative Type IV pilus biogenesis protein PilO\tK02664 pilO; type IV pilus assembly protein PilO" }, { "name":"NITINOP_1769 putative Type IV pilus biogenesis protein PilN\tK02663 pilN; type IV pilus assembly protein PilN" }, { "name":"NITINOP_1768 pilM; Type IV pilus biogenesis protein PilM\tK02662 pilM; type IV pilus assembly protein PilM" }, { "name":"NITINOP_1152 putative Type IV pilus assembly protein PilV\tK02671 pilV; type IV pilus assembly protein PilV" }, { "name":"NITINOP_1153 putative Type IV pilus assembly protein PilW\tK02672 pilW; type IV pilus assembly protein PilW" }, { "name":"NITINOP_1157 putative Type IV pilus assembly protein PilY1\tK02674 pilY1; type IV pilus assembly protein PilY1" }, { "name":"NITINOP_0822 protein of unknown function\tK02651 flp; pilus assembly protein Flp\/PilA" }, { "name":"NITINOP_2342 conserved protein of unknown function\tK02651 flp; pilus assembly protein Flp\/PilA" }, { "name":"NITINOP_0823 exported protein of unknown function\tK02279 cpaB; pilus assembly protein CpaB" }, { "name":"NITINOP_0824 putative Pilus assembly protein CpaC\tK02280 cpaC; pilus assembly protein CpaC" }, { "name":"NITINOP_2348 Response regulator receiver protein\tK02282 cpaE; pilus assembly protein CpaE" }, { "name":"NITINOP_0829 cpaF; Pilus assembly ATPase CpaF\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]" }, { "name":"NITINOP_2349 Type II secretion system protein E\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]" } ] }, { "name":"03037 Cilium and associated proteins" }, { "name":"04812 Cytoskeleton proteins [BR:nio04812]", "children":[ { "name":"NITINOP_2842 conserved protein of unknown function\tK06990 MEMO1; MEMO1 family protein" }, { "name":"NITINOP_0089 mreB; cell wall structural complex MreBCD, actin-like component MreB\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"NITINOP_0290 ftsZ; GTP-binding tubulin-like cell division protein\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"NITINOP_0291 ftsA; ATP-binding cell division protein involved in recruitment of FtsK to Z ring\tK03590 ftsA; cell division protein FtsA" }, { "name":"NITINOP_0901 soj; Sporulation initiation inhibitor protein Soj\tK03496 parA; chromosome partitioning protein" }, { "name":"NITINOP_0900 parB; putative chromosome-partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"NITINOP_1439 conserved exported protein of unknown function\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" } ] }, { "name":"04147 Exosome [BR:nio04147]", "children":[ { "name":"NITINOP_2374 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"NITINOP_3157 gapA; Glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"NITINOP_3158 pgk; Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"NITINOP_2630 pykA; Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"NITINOP_1790 groEL; chaperone Hsp60, peptide-dependent ATPase, heat shock protein\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"NITINOP_0514 dnaK; chaperone Hsp70, co-chaperone with DnaJ\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_2540 dnaK; chaperone Hsp70 in DNA biosynthesis\/cell division\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"NITINOP_0912 putative Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"NITINOP_1827 guaB; IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]" }, { "name":"NITINOP_1715 tufB; protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"NITINOP_1727 tufB; protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"NITINOP_0570 putative Calcium-transporting ATPase\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]" }, { "name":"NITINOP_0112 Uncharacterized HIT-like protein aq_141\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]" }, { "name":"NITINOP_0743 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0933 putative 2-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"NITINOP_0946 atoB; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"NITINOP_1556 ahcY; Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"NITINOP_1752 adk; Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]" }, { "name":"NITINOP_3216 apt; adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]" }, { "name":"NITINOP_1249 argH; Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]" }, { "name":"NITINOP_1250 argG; Argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]" }, { "name":"NITINOP_3078 fbp; Fructose-1,6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]" }, { "name":"NITINOP_1642 putative Formimidoyltransferase-cyclodeaminase\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" }, { "name":"NITINOP_0017 glgB; 1,4-alpha-glucan branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]" }, { "name":"NITINOP_1895 1,4-alpha-glucan branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]" }, { "name":"NITINOP_1778 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"NITINOP_2481 hemB; porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]" }, { "name":"NITINOP_1440 putative pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]" }, { "name":"NITINOP_2643 serA; D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"NITINOP_2673 purH; fused IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"NITINOP_2493 lpd; Dihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"NITINOP_1303 gdhA; Glutamate dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]" }, { "name":"NITINOP_0665 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"NITINOP_2009 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"NITINOP_3159 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"NITINOP_1254 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"NITINOP_0078 blc; Outer membrane lipoprotein Blc\tK03098 APOD; apolipoprotein D and lipocalin family protein" } ] }, { "name":"02048 Prokaryotic defense system [BR:nio02048]", "children":[ { "name":"NITINOP_1013 cas1; CRISPR-associated endonuclease Cas1 1\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"NITINOP_2510 cas4-cas; CRISPR-associated protein Cas4\/endonuclease Cas1 fusion\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"NITINOP_2583 cas1; CRISPR-associated endonuclease Cas1 1\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"NITINOP_1011 cas2; CRISPR-associated endoribonuclease Cas2 2\tK09951 cas2; CRISPR-associated protein Cas2" }, { "name":"NITINOP_1019 cas2; CRISPR-associated endoribonuclease Cas2 1\tK09951 cas2; CRISPR-associated protein Cas2" }, { "name":"NITINOP_2511 cas2; CRISPR-associated endoribonuclease Cas2 1\tK09951 cas2; CRISPR-associated protein Cas2" }, { "name":"NITINOP_2584 cas2; CRISPR-associated endoribonuclease Cas2 1\tK09951 cas2; CRISPR-associated protein Cas2" }, { "name":"NITINOP_2498 cas3; CRISPR-associated helicase Cas3\tK07012 cas3; CRISPR-associated endonuclease\/helicase Cas3 [EC:3.1.-.- 5.6.2.4]" }, { "name":"NITINOP_2578 Metal dependent phosphohydrolase\tK07012 cas3; CRISPR-associated endonuclease\/helicase Cas3 [EC:3.1.-.- 5.6.2.4]" }, { "name":"NITINOP_2582 CRISPR-associated exonuclease, Cas4 family\tK07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]" }, { "name":"NITINOP_2580 conserved protein of unknown function\tK19117 csd1; CRISPR-associated protein Csd1" }, { "name":"NITINOP_2581 CRISPR-associated protein Csd2\tK19118 csd2; CRISPR-associated protein Csd2" }, { "name":"NITINOP_2579 conserved protein of unknown function\tK19119 cas5d; CRISPR-associated protein Cas5d" }, { "name":"NITINOP_2500 csb; CRISPR-associated protein Csb1\tK19131 csb1; CRISPR-associated protein Csb1" }, { "name":"NITINOP_2501 csb; CRISPR-associated protein Csb2\tK19132 csb2; CRISPR-associated protein Csb2" }, { "name":"NITINOP_1046 conserved protein of unknown function\tK07061 cmr1; CRISPR-associated protein Cmr1" }, { "name":"NITINOP_1045 CRISPR-associated protein\tK19076 cmr2; CRISPR-associated protein Cmr2" }, { "name":"NITINOP_1044 CRISPR-associated protein (Cas_Cmr3)\tK09127 cmr3; CRISPR-associated protein Cmr3" }, { "name":"NITINOP_1041 CRISPR type III-B\/RAMP module RAMP protein Cmr4\tK09000 cmr4; CRISPR-associated protein Cmr4" }, { "name":"NITINOP_1039 CRISPR-associated protein, Cmr5 family\tK19141 cmr5; CRISPR-associated protein Cmr5" }, { "name":"NITINOP_1038 CRISPR type III-B\/RAMP module RAMP protein Cmr6\tK19142 cmr6; CRISPR-associated protein Cmr6" }, { "name":"NITINOP_0957 Type-1 restriction enzyme R protein\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]" }, { "name":"NITINOP_1343 Type I restriction-modification system, R subunit\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]" }, { "name":"NITINOP_2859 Type I site-specific deoxyribonuclease, HsdR family\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]" }, { "name":"NITINOP_0965 Restriction modification system DNA specificity subunit\tK01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]" }, { "name":"NITINOP_1335 putative Restriction modification system DNA specificity subunit\tK01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]" }, { "name":"NITINOP_2854 Putative restriction modification system DNA specificity domain (fragment)\tK01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]" }, { "name":"NITINOP_0968 Type I restriction-modification system protein\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]" }, { "name":"NITINOP_1334 N-6 DNA methylase\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]" }, { "name":"NITINOP_2850 putative type I restriction enzyme HindVIIP M protein\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]" }, { "name":"NITINOP_0383 avaIR; Type-2 restriction enzyme AvaI\tK01155 E3.1.21.4; type II restriction enzyme [EC:3.1.21.4]" }, { "name":"NITINOP_2046 dcm; Cytosine-specific methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"NITINOP_0523 Type III site-specific deoxyribonuclease\tK01156 res; type III restriction enzyme [EC:3.1.21.5]" }, { "name":"NITINOP_2696 Type III restriction enzyme, res subunit, putative (fragment)\tK01156 res; type III restriction enzyme [EC:3.1.21.5]" }, { "name":"NITINOP_3311 putative type III restriction-modification system, Res subunit\tK01156 res; type III restriction enzyme [EC:3.1.21.5]" }, { "name":"NITINOP_0529 Site-specific DNA-methyltransferase (Adenine-specific)\tK07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]" }, { "name":"NITINOP_2700 protein of unknown function\tK07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]" }, { "name":"NITINOP_3313 DNA methylase N-4\/N-6 domain protein\tK07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72]" }, { "name":"NITINOP_1784 Mrr restriction system protein\tK07448 mrr; restriction system protein" }, { "name":"NITINOP_0158 protein of unknown function\tK06218 relE; mRNA interferase RelE\/StbE" }, { "name":"NITINOP_1817 higB; Toxin HigB-1\tK07334 higB-1; toxin HigB-1" }, { "name":"NITINOP_3309 conserved protein of unknown function\tK07334 higB-1; toxin HigB-1" }, { "name":"NITINOP_1223 DNA-binding protein\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA" }, { "name":"NITINOP_1818 Addiction module antidote protein, HigA family\tK21498 higA-1; antitoxin HigA-1" }, { "name":"NITINOP_1043 PilT-like protein\tK28279 vapC22; ribonuclease VapC22 [EC:3.1.-.-]" }, { "name":"NITINOP_1042 Prevent-host-death family protein\tK28280 vapB22; antitoxin VapB22" }, { "name":"NITINOP_1065 vapC; Ribonuclease VapC37\tK28143 vapC24S; ribonuclease VapC24\/25\/29\/31\/33\/37\/38\/39\/41\/43\/44\/48 [EC:3.1.-.-]" }, { "name":"NITINOP_0290 ftsZ; GTP-binding tubulin-like cell division protein\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"NITINOP_0089 mreB; cell wall structural complex MreBCD, actin-like component MreB\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"NITINOP_0506 gltX; Glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"NITINOP_0119 conserved protein of unknown function\tK28186 hepT; HepT family RNase toxin" }, { "name":"NITINOP_2068 conserved protein of unknown function\tK28186 hepT; HepT family RNase toxin" }, { "name":"NITINOP_0118 putative Nucleotidyltransferase\tK28187 mntA; MntA family adenylyltransferase antitoxin" }, { "name":"NITINOP_0510 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" } ] }, { "name":"04030 G protein-coupled receptors" }, { "name":"04050 Cytokine receptors" }, { "name":"04054 Pattern recognition receptors" }, { "name":"03310 Nuclear receptors" }, { "name":"04040 Ion channels" }, { "name":"04031 GTP-binding proteins" }, { "name":"04052 Cytokines and neuropeptides" }, { "name":"04515 Cell adhesion molecules" }, { "name":"04090 CD molecules [BR:nio04090]", "children":[ { "name":"NITINOP_2246 Rh50; Ammonium transporter Rh50\tK06580 SLC42A; ammonium transporter Rh" } ] }, { "name":"01504 Antimicrobial resistance genes [BR:nio01504]", "children":[ { "name":"NITINOP_0166 ttgA; Toluene efflux pump periplasmic linker protein TtgA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0321 putative Acriflavine resistance protein acrA\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0715 putative RND-type efflux transporter, membrane-fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_1220 putative RND efflux system, membrane fusion protein\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"NITINOP_0165 acrB; multidrug efflux system protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0322 acrB; Acriflavin resistance protein acrB\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0714 putative RND-type efflux transporter, transmembrane pump\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_1221 putative RND efflux system, multidrug resistance protein\tK18138 acrB; multidrug efflux pump" }, { "name":"NITINOP_0164 oprM; Outer membrane protein OprM\tK18139 oprM; outer membrane protein, multidrug efflux system" }, { "name":"NITINOP_2976 Transcriptional regulator, MerR family\tK19591 cueR; MerR family transcriptional regulator, copper efflux regulator" }, { "name":"NITINOP_0013 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_0713 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" }, { "name":"NITINOP_3265 putative Outer membrane efflux protein\tK12340 tolC; outer membrane protein" } ] }, { "name":"00535 Proteoglycans" }, { "name":"00536 Glycosaminoglycan binding proteins" }, { "name":"00537 Glycosylphosphatidylinositol (GPI)-anchored proteins" }, { "name":"04091 Lectins" }, { "name":"04990 Domain-containing proteins not elsewhere classified" } ] }, { "name":"09185 Viral protein families", "children":[ { "name":"03200 Viral proteins" }, { "name":"03210 Viral fusion proteins" } ] }, { "name":"09184 RNA family", "children":[ { "name":"03100 Non-coding RNAs [BR:nio03100]", "children":[ { "name":"NITINOP_tRNA20 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"NITINOP_tRNA32 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"NITINOP_tRNA5 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"NITINOP_tRNA1 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA11 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA31 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA35 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA43 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"NITINOP_tRNA38 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn" }, { "name":"NITINOP_tRNA22 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp" }, { "name":"NITINOP_tRNA13 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys" }, { "name":"NITINOP_tRNA45 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"NITINOP_tRNA46 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"NITINOP_tRNA3 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"NITINOP_tRNA47 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"NITINOP_tRNA16 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"NITINOP_tRNA25 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"NITINOP_tRNA4 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"NITINOP_tRNA12 tRNA-His\tK14226 tRNA-His; tRNA His" }, { "name":"NITINOP_tRNA19 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"NITINOP_tRNA23 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA24 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA6 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA8 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA9 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"NITINOP_tRNA42 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"NITINOP_tRNA44 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"NITINOP_tRNA27 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA40 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA48 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"NITINOP_tRNA30 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe" }, { "name":"NITINOP_tRNA10 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"NITINOP_tRNA33 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"NITINOP_tRNA34 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"NITINOP_tRNA26 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA28 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA29 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA41 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"NITINOP_tRNA14 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"NITINOP_tRNA17 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"NITINOP_tRNA37 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"NITINOP_tRNA18 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp" }, { "name":"NITINOP_tRNA15 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr" }, { "name":"NITINOP_tRNA21 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"NITINOP_tRNA39 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"NITINOP_tRNA7 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"NITINOP_23s_rRNA1 ribosomal RNA 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"NITINOP_5s_rRNA_1 ribosomal RNA 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"NITINOP_misc_RNA7 tmRNA\tK15035 ssrA; transfer-messenger RNA" }, { "name":"NITINOP_misc_RNA8 SRP_bact\tK01983 ffs; signal recognition particle 4.5S RNA" } ] } ] } ] }, { "name":"09190 Not Included in Pathway or Brite", "children":[ { "name":"09191 Unclassified: metabolism", "children":[ { "name":"99980 Enzymes with EC numbers", "children":[ { "name":"NITINOP_0338 dfrA; putative dihydroflavonol-4-reductase\tK00091 E1.1.1.219; dihydroflavonol-4-reductase [EC:1.1.1.219]" }, { "name":"NITINOP_2863 Oxidoreductase, zinc-binding dehydrogenase family\tK00344 qor; NADPH:quinone reductase [EC:1.6.5.5]" }, { "name":"NITINOP_0804 msrA; Peptide methionine sulfoxide reductase MsrA\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]" }, { "name":"NITINOP_1317 msrA; Peptide methionine sulfoxide reductase MsrA\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]" }, { "name":"NITINOP_2916 msrB; Peptide methionine sulfoxide reductase MsrB\tK07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]" }, { "name":"NITINOP_0603 yqjG; Glutathionyl-hydroquinone reductase YqjG\tK07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]" }, { "name":"NITINOP_0983 putative Ferredoxin-thioredoxin reductase, catalytic subunit\tK17892 FTRC; ferredoxin-thioredoxin reductase catalytic chain [EC:1.8.7.2]" }, { "name":"NITINOP_1436 ccpA; Cytochrome c551 peroxidase\tK00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]" }, { "name":"NITINOP_2804 bcp; putative peroxiredoxin bcp\tK03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]" }, { "name":"NITINOP_2203 putative Thiol peroxidase (Modular protein)\tK11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]" }, { "name":"NITINOP_2922 putative Peroxiredoxin\tK24158 prx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]" }, { "name":"NITINOP_0175 putative Quercetin 2,3-dioxygenase\tK06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]" }, { "name":"NITINOP_1797 Chlorite dismutase\tK09162 cld; chlorite dismutase [EC:1.13.11.49]" }, { "name":"NITINOP_1014 conserved exported protein of unknown function\tK22349 mnxG; manganese oxidase [EC:1.16.3.3]" }, { "name":"NITINOP_2791 putative Ferredoxin-NADP(+) reductase\tK00528 fpr; ferredoxin\/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]" }, { "name":"NITINOP_2319 arsC; Arsenate reductase\tK00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]" }, { "name":"NITINOP_0619 arsC; Protein ArsC\tK03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]" }, { "name":"NITINOP_0753 Radical SAM domain protein\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]" }, { "name":"NITINOP_2517 conserved protein of unknown function\tK04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4]" }, { "name":"NITINOP_0752 pcm; Protein-L-isoaspartate O-methyltransferase\tK00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]" }, { "name":"NITINOP_0917 pcm; L-isoaspartate protein carboxylmethyltransferase type II\tK00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]" }, { "name":"NITINOP_2220 putative fatty acid methyltransferase\tK00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]" }, { "name":"NITINOP_0810 Cobalamin B12-binding\/Radical SAM family protein\tK22704 hpnR; hopanoid C-3 methylase [EC:2.1.1.-]" }, { "name":"NITINOP_2438 conserved protein of unknown function\tK00612 nodU; carbamoyltransferase [EC:2.1.3.-]" }, { "name":"NITINOP_2076 lnt; Apolipoprotein N-acyltransferase\tK03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]" }, { "name":"NITINOP_1406 aat; Leucyl\/phenylalanyl-tRNA--protein transferase\tK00684 aat; leucyl\/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]" }, { "name":"NITINOP_0880 conserved membrane protein of unknown function\tK22452 tgpA; protein-glutamine gamma-glutamyltransferase [EC:2.3.2.13]" }, { "name":"NITINOP_1671 conserved protein of unknown function\tK22310 olsB; L-ornithine Nalpha-acyltransferase [EC:2.3.2.30]" }, { "name":"NITINOP_2743 putative Glycosyl transferase, family 2\tK21349 ggs; glucosylglycerate synthase [EC:2.4.1.268]" }, { "name":"NITINOP_0356 Deoxyhypusine synthase family protein\tK00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]" }, { "name":"NITINOP_1202 conserved protein of unknown function\tK06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]" }, { "name":"NITINOP_2091 lgt; Prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]" }, { "name":"NITINOP_1785 putative (Glutamate-ammonia-ligase) adenylyltransferase, subunit A (Modular protein)\tK00982 glnE; [glutamine synthetase] adenylyltransferase \/ [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89]" }, { "name":"NITINOP_1786 glnEb; (Glutamate-ammonia-ligase) adenylyltransferase, subunit B\tK00982 glnE; [glutamine synthetase] adenylyltransferase \/ [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89]" }, { "name":"NITINOP_0835 ydiU; conserved hypothetical protein\tK08997 SELENOO; protein adenylyltransferase [EC:2.7.7.108]" }, { "name":"NITINOP_1236 putative Phosphoenolpyruvate synthase\tK22579 rph; rifampicin phosphotransferase [EC:2.7.9.6]" }, { "name":"NITINOP_1229 conserved protein of unknown function\tK23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]" }, { "name":"NITINOP_1475 putative enzyme\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]" }, { "name":"NITINOP_2000 trpH; Phosphoesterase\tK07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97]" }, { "name":"NITINOP_2310 conserved protein of unknown function\tK08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]" }, { "name":"NITINOP_3012 Response regulator with HD-GYP domain\tK07814 K07814; cyclic di-GMP phosphodiesterase [EC:3.1.4.-]" }, { "name":"NITINOP_2250 putative Phosphohydrolase\tK25135 K25135; cyclic di-GMP phosphodiesterase [EC:3.1.4.-]" }, { "name":"NITINOP_3068 yabD; Uncharacterized deoxyribonuclease YabD\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]" }, { "name":"NITINOP_3052 def; Peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]" }, { "name":"NITINOP_1365 putative Polysaccharide deacetylase\tK22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]" }, { "name":"NITINOP_0882 conserved protein of unknown function\tK03924 moxR; MoxR-like ATPase [EC:3.6.3.-]" }, { "name":"NITINOP_2876 conserved protein of unknown function\tK22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]" }, { "name":"NITINOP_0774 nnr; Bifunctional NAD(P)H-hydrate repair enzyme Nnr [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase; NAD(P)H-hydrate epimerase]\tK23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase \/ NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]" }, { "name":"NITINOP_1391 conserved protein of unknown function\tK06864 larE; cysteine-dependent pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase [EC:4.4.1.37 4.4.1.45]" }, { "name":"NITINOP_1200 conserved protein of unknown function\tK09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]" }, { "name":"NITINOP_2942 yloB; Calcium-transporting ATPase\tK01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]" }, { "name":"NITINOP_2960 cadA; putative cadmium-transporting ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]" }, { "name":"NITINOP_1612 mgtA; magnesium transporter\tK01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14]" }, { "name":"NITINOP_0660 ctpF; putative cation-transporting ATPase F\tK12953 ctpF; cation-transporting P-type ATPase F [EC:7.2.2.-]" } ] }, { "name":"99981 Carbohydrate metabolism" }, { "name":"99982 Energy metabolism", "children":[ { "name":"NITINOP_0511 iscU; iron-binding protein believed to be involved in Fe-S protein formation or repair; function as a scaffold for the assembly of the transiently bound Fe\/S cluster\tK04488 iscU; nitrogen fixation protein NifU and related proteins" }, { "name":"NITINOP_0982 conserved protein of unknown function\tK02448 norD; nitric oxide reductase NorD protein" }, { "name":"NITINOP_0182 norQ; Protein NorQ\tK04748 norQ; nitric oxide reductase NorQ protein" }, { "name":"NITINOP_3305 napG; Ferredoxin-type protein NapG\tK02573 napG; ferredoxin-type protein NapG" }, { "name":"NITINOP_0918 conserved protein of unknown function\tK09165 K09165; dodecin" } ] }, { "name":"99983 Lipid metabolism" }, { "name":"99984 Nucleotide metabolism" }, { "name":"99985 Amino acid metabolism", "children":[ { "name":"NITINOP_0288 yggS; putative enzyme\tK06997 yggS; PLP dependent protein" } ] }, { "name":"99986 Glycan metabolism", "children":[ { "name":"NITINOP_0661 conserved exported protein of unknown function\tK08992 lapA; lipopolysaccharide assembly protein A" }, { "name":"NITINOP_0776 conserved exported protein of unknown function\tK08992 lapA; lipopolysaccharide assembly protein A" }, { "name":"NITINOP_3092 Glycosyl transferase family 25\tK07270 K07270; glycosyl transferase, family 25" } ] }, { "name":"99987 Cofactor metabolism", "children":[ { "name":"NITINOP_1211 Universal stress protein (Usp):ABC1 family\tK03688 ubiB; ubiquinone biosynthesis protein" }, { "name":"NITINOP_1966 mobB; Molybdopterin-guanine dinucleotide biosynthesis protein B\tK03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein" } ] }, { "name":"99988 Secondary metabolism", "children":[ { "name":"NITINOP_2865 Poly(3-hydroxybutyrate) depolymerase-like protein (fragment)\tK03932 lpqC; polyhydroxybutyrate depolymerase" } ] }, { "name":"99999 Others", "children":[ { "name":"NITINOP_0834 putative Carboxylesterase\tK06999 K06999; phospholipase\/carboxylesterase" } ] } ] }, { "name":"09192 Unclassified: genetic information processing", "children":[ { "name":"99973 Transcription", "children":[ { "name":"NITINOP_2570 cspE; DNA-binding transcriptional repressor\tK03704 cspA; cold shock protein" }, { "name":"NITINOP_1776 glnK; nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB\tK04752 glnK; nitrogen regulatory protein P-II 2" }, { "name":"NITINOP_0815 conserved protein of unknown function\tK07743 K07743; transcriptional regulator" } ] }, { "name":"99974 Translation", "children":[ { "name":"NITINOP_0859 putative RNA-metabolising metallo-beta-lactamase\tK07576 K07576; metallo-beta-lactamase family protein" } ] }, { "name":"99975 Protein processing", "children":[ { "name":"NITINOP_3024 clpS; ATP-dependent Clp protease adapter protein ClpS\tK06891 clpS; ATP-dependent Clp protease adaptor protein ClpS" }, { "name":"NITINOP_1081 tig; Trigger factor\tK03545 tig; trigger factor" }, { "name":"NITINOP_3354 putative Urease accessory protein UreF\tK03188 ureF; urease accessory protein" }, { "name":"NITINOP_3353 ureG; Urease accessory protein UreG\tK03189 ureG; urease accessory protein" }, { "name":"NITINOP_3352 putative Urease accessory protein UreD\tK03190 ureD; urease accessory protein" }, { "name":"NITINOP_0987 smpB; SsrA-binding protein\tK03664 smpB; SsrA-binding protein" }, { "name":"NITINOP_0582 hypC; Hydrogenase expression\/formation protein HypC\tK04653 hypC; hydrogenase expression\/formation protein HypC" }, { "name":"NITINOP_0581 hypD; Hydrogenase expression\/formation protein HypD\tK04654 hypD; hydrogenase expression\/formation protein HypD" }, { "name":"NITINOP_0580 hypE; hydrogenase maturation protein HypE\tK04655 hypE; hydrogenase expression\/formation protein HypE" }, { "name":"NITINOP_0583 hypF; Carbamoyltransferase HypF\tK04656 hypF; hydrogenase maturation protein HypF" }, { "name":"NITINOP_2108 conserved protein of unknown function\tK07391 comM; magnesium chelatase family protein" }, { "name":"NITINOP_1971 conserved protein of unknown function\tK07394 K07394; SM-20-related protein" }, { "name":"NITINOP_1307 Membrane-bound serine protease\tK07403 nfeD; membrane-bound serine protease (ClpP class)" } ] }, { "name":"99976 Replication and repair", "children":[ { "name":"NITINOP_2662 yicR; protein associated with replication fork, possible DNA repair protein\tK03630 radC; DNA repair protein RadC" }, { "name":"NITINOP_2977 DNA repair protein RadC\tK03630 radC; DNA repair protein RadC" }, { "name":"NITINOP_1265 RmuC-domain protein\tK09760 rmuC; DNA recombination protein RmuC" }, { "name":"NITINOP_3251 conserved protein of unknown function\tK07460 yraN; putative endonuclease" }, { "name":"NITINOP_0964 Excinuclease ABC C subunit domain protein\tK07461 K07461; putative endonuclease" }, { "name":"NITINOP_0083 smf; conserved hypothetical protein\tK04096 smf; DNA processing protein" }, { "name":"NITINOP_0972 rarA; Replication-associated recombination protein A\tK07478 ycaJ; putative ATPase" }, { "name":"NITINOP_2031 conserved protein of unknown function\tK07501 K07501; 3'-5' exonuclease" }, { "name":"NITINOP_0875 transposase (fragment)\tK07483 K07483; transposase" }, { "name":"NITINOP_0925 transposase (fragment)\tK07483 K07483; transposase" }, { "name":"NITINOP_2927 conserved protein of unknown function\tK07483 K07483; transposase" }, { "name":"NITINOP_1851 protein of unknown function\tK07491 rayT; REP-associated tyrosine transposase" }, { "name":"NITINOP_2855 conserved protein of unknown function\tK07491 rayT; REP-associated tyrosine transposase" }, { "name":"NITINOP_2054 Integrase, catalytic region (modular protein)\tK07497 K07497; putative transposase" }, { "name":"NITINOP_2437 transposase (fragment)\tK07497 K07497; putative transposase" }, { "name":"NITINOP_2928 insF; transposase\tK07497 K07497; putative transposase" } ] }, { "name":"99979 Viral proteins" }, { "name":"99998 Others", "children":[ { "name":"NITINOP_1078 ybaB; conserved hypothetical protein\tK09747 ebfC; nucleoid-associated protein EbfC" } ] } ] }, { "name":"09193 Unclassified: signaling and cellular processes", "children":[ { "name":"99977 Transport", "children":[ { "name":"NITINOP_0751 putative Amino acid transporter\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family" }, { "name":"NITINOP_1091 yfnA; Uncharacterized amino acid permease YfnA\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family" }, { "name":"NITINOP_2013 conserved membrane protein of unknown function\tK03301 TC.AAA; ATP:ADP antiporter, AAA family" }, { "name":"NITINOP_1516 putative Inorganic phosphate transporter\tK03306 TC.PIT; inorganic phosphate transporter, PiT family" }, { "name":"NITINOP_1540 Na+\/solute symporter\tK03307 TC.SSS; solute:Na+ symporter, SSS family" }, { "name":"NITINOP_0563 Sodium-dependent transporter\tK03453 TC.BASS; bile acid:Na+ symporter, BASS family" } ] }, { "name":"99978 Cell growth", "children":[ { "name":"NITINOP_0618 conserved protein of unknown function\tK07322 ytfE; regulator of cell morphogenesis and NO signaling" }, { "name":"NITINOP_2265 conserved protein of unknown function\tK06320 cgeB; spore maturation protein CgeB" }, { "name":"NITINOP_3370 kipA; KipI antagonist\tK06350 kipA; antagonist of KipI" }, { "name":"NITINOP_3368 ybgJ; putative hydrolase subunit\tK06351 kipI; inhibitor of KinA" }, { "name":"NITINOP_1426 putative anti-sigma factor antagonist BtrV\tK06378 spoIIAA; stage II sporulation protein AA (anti-sigma F factor antagonist)" }, { "name":"NITINOP_3248 putative Murein hydrolase EnvC\tK22719 envC; murein hydrolase activator" } ] }, { "name":"99993 Cell motility", "children":[ { "name":"NITINOP_2190 conserved exported protein of unknown function\tK07337 K07337; penicillin-binding protein activator" } ] }, { "name":"99995 Signaling proteins", "children":[ { "name":"NITINOP_0517 bipA; GTP-binding protein\tK06207 typA; GTP-binding protein" }, { "name":"NITINOP_1159 ybeZ; putative enzyme with nucleoside triphosphate hydrolase domain\tK06217 phoH; phosphate starvation-inducible protein PhoH and related proteins" }, { "name":"NITINOP_0307 conserved protein of unknown function\tK09767 yajQ; cyclic-di-GMP-binding protein" } ] }, { "name":"99992 Structural proteins", "children":[ { "name":"NITINOP_1328 putative Outer membrane lipoprotein carrier protein LolA\tK03634 lolA; outer membrane lipoprotein carrier protein" }, { "name":"NITINOP_0606 putative VacJ-like lipoprotein\tK04754 mlaA; phospholipid-binding lipoprotein MlaA" }, { "name":"NITINOP_2831 putative Periplasmic chaperone Skp\tK06142 hlpA; outer membrane protein" }, { "name":"NITINOP_3135 putative Outer membrane chaperone Skp\tK06142 hlpA; outer membrane protein" }, { "name":"NITINOP_3136 putative Outer membrane chaperone Skp\tK06142 hlpA; outer membrane protein" }, { "name":"NITINOP_0390 putative Outer membrane lipoprotein Slp\tK07285 slp; outer membrane lipoprotein" }, { "name":"NITINOP_2632 Putative Outer membrane lipoprotein Slp (modular protein)\tK07285 slp; outer membrane lipoprotein" }, { "name":"NITINOP_1174 exported protein of unknown function\tK07289 asmA; AsmA protein" }, { "name":"NITINOP_3030 Multidrug resistance efflux pump\tK01993 ABC-2.TX; HlyD family secretion protein" }, { "name":"NITINOP_0571 RND-type efflux transporter, membrane-fusion protein\tK02005 ABC.CD.TX; HlyD family secretion protein" }, { "name":"NITINOP_2776 putative Multidrug efflux transporter, RND family\tK02005 ABC.CD.TX; HlyD family secretion protein" }, { "name":"NITINOP_0071 ccmE; Cytochrome c-type biogenesis protein CcmE\tK02197 ccmE; cytochrome c-type biogenesis protein CcmE" }, { "name":"NITINOP_0067 ccmI; Cytochrome c-type biogenesis protein CcmI\tK02200 ccmH; cytochrome c-type biogenesis protein CcmH" }, { "name":"NITINOP_0068 ccmH; Cytochrome c-type biogenesis protein CcmH\tK02200 ccmH; cytochrome c-type biogenesis protein CcmH" } ] }, { "name":"99994 Others", "children":[ { "name":"NITINOP_1326 phoU; Phosphate transport system protein PhoU\tK02039 phoU; phosphate transport system protein" }, { "name":"NITINOP_3283 putative Bacterioferritin-associated ferredoxin\tK02192 bfd; bacterioferritin-associated ferredoxin" }, { "name":"NITINOP_1511 cutA; Divalent-cation tolerance protein CutA\tK03926 cutA; periplasmic divalent cation tolerance protein" }, { "name":"NITINOP_3182 putative Transcriptional regulator ModE\tK03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]" }, { "name":"NITINOP_0369 pcoB; putative copper resistance protein B\tK07233 pcoB; copper resistance protein B" }, { "name":"NITINOP_3034 conserved membrane protein of unknown function\tK07234 K07234; uncharacterized protein involved in response to NO" } ] } ] }, { "name":"09194 Poorly characterized", "children":[ { "name":"99996 General function prediction only", "children":[ { "name":"NITINOP_1907 Globin-like protein\tK06886 glbN; hemoglobin" }, { "name":"NITINOP_3147 Hemoglobin-like protein (fragment)\tK06886 glbN; hemoglobin" }, { "name":"NITINOP_1521 Patatin\tK07001 K07001; NTE family protein" }, { "name":"NITINOP_2725 Haloacid dehalogenase, subfamily IA\tK07025 K07025; putative hydrolase of the HAD superfamily" }, { "name":"NITINOP_0976 erpA; Iron-sulfur cluster insertion protein ErpA 2\tK15724 erpA; iron-sulfur cluster insertion protein" }, { "name":"NITINOP_2596 tRNA-processing RNAse BN\tK07058 K07058; membrane protein" }, { "name":"NITINOP_0610 putative Phosphoribosyltransferase\tK07100 K07100; putative phosphoribosyl transferase" }, { "name":"NITINOP_1456 conserved exported protein of unknown function\tK03744 lemA; LemA protein" }, { "name":"NITINOP_0342 conserved membrane protein of unknown function\tK08972 K08972; putative membrane protein" }, { "name":"NITINOP_1458 conserved protein of unknown function\tK08988 K08988; putative membrane protein" } ] }, { "name":"99997 Function unknown", "children":[ { "name":"NITINOP_2526 Ankyrin repeat-containing protein (fragment)\tK06867 K06867; uncharacterized protein" }, { "name":"NITINOP_1457 conserved membrane protein of unknown function\tK06872 K06872; uncharacterized protein" }, { "name":"NITINOP_3035 conserved exported protein of unknown function\tK06872 K06872; uncharacterized protein" }, { "name":"NITINOP_3143 conserved protein of unknown function\tK06885 K06885; uncharacterized protein" }, { "name":"NITINOP_2315 conserved protein of unknown function\tK06888 K06888; uncharacterized protein" }, { "name":"NITINOP_0194 conserved protein of unknown function\tK06889 K06889; uncharacterized protein" }, { "name":"NITINOP_2409 conserved protein of unknown function\tK06889 K06889; uncharacterized protein" }, { "name":"NITINOP_3069 conserved protein of unknown function\tK06962 K06962; uncharacterized protein" }, { "name":"NITINOP_1534 conserved protein of unknown function\tK06996 K06996; uncharacterized protein" }, { "name":"NITINOP_1622 putative Hydrolase, alpha\/beta fold family\tK07019 K07019; uncharacterized protein" }, { "name":"NITINOP_1931 putative Amidohydrolase\tK07045 K07045; uncharacterized protein" }, { "name":"NITINOP_1129 conserved protein of unknown function\tK07071 K07071; uncharacterized protein" }, { "name":"NITINOP_0837 conserved membrane protein of unknown function\tK07086 K07086; uncharacterized protein" }, { "name":"NITINOP_2175 conserved membrane protein of unknown function\tK07090 K07090; uncharacterized protein" }, { "name":"NITINOP_1666 Tat pathway signal sequence domain protein\tK07093 K07093; uncharacterized protein" }, { "name":"NITINOP_2223 protein of unknown function\tK07126 K07126; uncharacterized protein" }, { "name":"NITINOP_2591 conserved protein of unknown function\tK07126 K07126; uncharacterized protein" }, { "name":"NITINOP_1348 conserved protein of unknown function\tK07133 K07133; uncharacterized protein" }, { "name":"NITINOP_2856 ATPase, AAA+ superfamily\tK07133 K07133; uncharacterized protein" }, { "name":"NITINOP_2860 protein of unknown function\tK07133 K07133; uncharacterized protein" }, { "name":"NITINOP_1218 putative Peptidase S16, lon-like\tK07157 K07157; uncharacterized protein" }, { "name":"NITINOP_0109 conserved protein of unknown function\tK07164 K07164; uncharacterized protein" }, { "name":"NITINOP_0906 putative membrane protein insertion efficiency factor\tK08998 K08998; uncharacterized protein" }, { "name":"NITINOP_2470 conserved protein of unknown function\tK08999 K08999; uncharacterized protein" }, { "name":"NITINOP_2471 conserved protein of unknown function\tK08999 K08999; uncharacterized protein" }, { "name":"NITINOP_0792 conserved protein of unknown function\tK09005 K09005; uncharacterized protein" }, { "name":"NITINOP_3286 conserved exported protein of unknown function\tK09005 K09005; uncharacterized protein" }, { "name":"NITINOP_3231 conserved protein of unknown function\tK09117 K09117; uncharacterized protein" }, { "name":"NITINOP_0181 conserved protein of unknown function\tK09131 K09131; uncharacterized protein" }, { "name":"NITINOP_3118 HEPN domain protein\tK09132 K09132; uncharacterized protein" }, { "name":"NITINOP_1838 conserved protein of unknown function\tK09137 K09137; uncharacterized protein" }, { "name":"NITINOP_2808 conserved protein of unknown function\tK09143 K09143; uncharacterized protein" }, { "name":"NITINOP_0785 conserved protein of unknown function\tK09764 K09764; uncharacterized protein" }, { "name":"NITINOP_0130 yciI; Protein YciI\tK09780 K09780; uncharacterized protein" }, { "name":"NITINOP_2798 conserved protein of unknown function\tK09794 K09794; uncharacterized protein" }, { "name":"NITINOP_0737 conserved protein of unknown function\tK09803 K09803; uncharacterized protein" }, { "name":"NITINOP_3316 conserved exported protein of unknown function\tK09807 K09807; uncharacterized protein" }, { "name":"NITINOP_2191 conserved protein of unknown function\tK09859 K09859; uncharacterized protein" }, { "name":"NITINOP_1349 conserved membrane protein of unknown function\tK09922 K09922; uncharacterized protein" }, { "name":"NITINOP_3142 conserved membrane protein of unknown function\tK09928 K09928; uncharacterized protein" }, { "name":"NITINOP_2007 conserved protein of unknown function\tK09930 K09930; uncharacterized protein" }, { "name":"NITINOP_0191 conserved protein of unknown function\tK09931 K09931; uncharacterized protein" }, { "name":"NITINOP_1865 conserved membrane protein of unknown function\tK09939 K09939; uncharacterized protein" }, { "name":"NITINOP_2602 conserved exported protein of unknown function\tK09978 K09978; uncharacterized protein" }, { "name":"NITINOP_0184 conserved protein of unknown function\tK01163 K01163; uncharacterized protein" }, { "name":"NITINOP_2809 conserved protein of unknown function\tK07502 yprB; uncharacterized protein" } ] } ] } ] } ] }