{
	"name":"nnt04052",
	"children":[
	{
		"name":"Cytokines",
		"children":[
		{
			"name":"Interleukins",
			"children":[
			{
				"name":"104403914 interleukin-1 receptor antagonist protein-like\tK04519 IL1B; interleukin 1 beta"
			},
			{
				"name":"104407025 IL4; interleukin-4\tK05430 IL4; interleukin 4"
			},
			{
				"name":"104411997 IL6; LOW QUALITY PROTEIN: interleukin-6\tK05405 IL6; interleukin 6"
			},
			{
				"name":"104412614 IL10; interleukin-10\tK05443 IL10; interleukin 10"
			},
			{
				"name":"104412611 IL12A; interleukin-12 subunit alpha\tK05406 IL12A; interleukin 12A"
			},
			{
				"name":"104407355 IL12B; interleukin-12 subunit beta\tK05425 IL12B; interleukin 12B"
			},
			{
				"name":"104401679 IL15; interleukin-15\tK05433 IL15; interleukin 15"
			},
			{
				"name":"104401183 IL16; pro-interleukin-16\tK22628 IL16; interleukin 16"
			},
			{
				"name":"104408968 IL17A; interleukin-17A\tK05489 IL17A; interleukin 17A"
			},
			{
				"name":"104407342 IL17B; interleukin-17B\tK05490 IL17B; interleukin 17B"
			},
			{
				"name":"104406896 IL17D; interleukin-17D\tK05492 IL17D; interleukin 17D"
			},
			{
				"name":"104408969 interleukin-17F-like\tK05494 IL17F; interleukin 17F"
			},
			{
				"name":"104411799 IL18; interleukin-18\tK05482 IL18; interleukin 18"
			},
			{
				"name":"104412615 interleukin-20-like\tK22667 IL20; interleukin 20"
			},
			{
				"name":"104403184 IL21; interleukin-21\tK05434 IL21; interleukin 21"
			},
			{
				"name":"104405136 IL22; interleukin-22\tK05445 IL22; interleukin 22"
			},
			{
				"name":"104412266 EBI3; LOW QUALITY PROTEIN: interleukin-27 subunit beta\tK24476 EBI3; interleukin 27 subunit beta"
			}
			]
		},
		{
			"name":"Interferons",
			"children":[
			{
				"name":"104411022 interferon beta-like\tK05414 IFNA; interferon alpha"
			},
			{
				"name":"104400091 interferon-like\tK05415 IFNB; interferon beta"
			},
			{
				"name":"104405137 IFNG; interferon gamma\tK04687 IFNG; interferon gamma"
			}
			]
		},
		{
			"name":"CSF and other factors",
			"children":[
			{
				"name":"104404923 CSF1; macrophage colony-stimulating factor 1\tK05453 CSF1; macrophage colony-stimulating factor 1"
			},
			{
				"name":"104412244 myelomonocytic growth factor-like\tK05423 CSF3; granulocyte colony-stimulating factor"
			},
			{
				"name":"104410485 somatotropin\tK05438 GH; growth hormone"
			},
			{
				"name":"104402265 THPO; thrombopoietin\tK06854 THPO; thrombopoietin"
			},
			{
				"name":"104401563 LIF; leukemia inhibitory factor\tK05419 LIF; leukemia inhibitory factor"
			}
			]
		},
		{
			"name":"Chemokines",
			"children":[
			{
				"name":"104410408 C-C motif chemokine 1-like\tK05514 CCL1; C-C motif chemokine 1"
			},
			{
				"name":"104407104 C-C motif chemokine 4 homolog\tK12964 CCL4; C-C motif chemokine 4"
			},
			{
				"name":"104407110 LOW QUALITY PROTEIN: C-C motif chemokine 4-like\tK12964 CCL4; C-C motif chemokine 4"
			},
			{
				"name":"104407105 CCL5; C-C motif chemokine 5\tK12499 CCL5; C-C motif chemokine 5"
			},
			{
				"name":"104409899 CCL19; C-C motif chemokine 19\tK05512 CCL19; C-C motif chemokine 19"
			},
			{
				"name":"104408870 CCL20; C-C motif chemokine 20\tK14625 CCL20; C-C motif chemokine 20"
			},
			{
				"name":"104409897 CCL21; C-C motif chemokine 21\tK16062 CCL21; C-C motif chemokine 21"
			},
			{
				"name":"104407495 interleukin-8-like\tK10030 IL8; interleukin 8"
			},
			{
				"name":"104407496 interleukin-8-like\tK10030 IL8; interleukin 8"
			},
			{
				"name":"104407500 interleukin-8-like\tK10030 IL8; interleukin 8"
			},
			{
				"name":"104408654 CXCL12; stromal cell-derived factor 1\tK10031 CXCL12; C-X-C motif chemokine 12"
			},
			{
				"name":"104411173 C-X-C motif chemokine 13-like\tK10032 CXCL13; C-X-C motif chemokine 13"
			},
			{
				"name":"104411181 alveolar macrophage chemotactic factor-like\tK10032 CXCL13; C-X-C motif chemokine 13"
			},
			{
				"name":"104411188 alveolar macrophage chemotactic factor-like\tK10032 CXCL13; C-X-C motif chemokine 13"
			},
			{
				"name":"104401536 CXCL14; C-X-C motif chemokine 14\tK10033 CXCL14; C-X-C motif chemokine 14"
			},
			{
				"name":"104402097 fractalkine-like\tK05508 CX3CL1; C-X3-C motif chemokine 1"
			},
			{
				"name":"104407051 lymphotactin-like\tK05507 XCL; C motif chemokine"
			},
			{
				"name":"104400495 PROK2; prokineticin-2\tK24191 PROK; prokineticin"
			},
			{
				"name":"104408422 PROK1; prokineticin-1\tK24191 PROK; prokineticin"
			},
			{
				"name":"104411759 CYTL1; cytokine-like protein 1\tK25418 CYTL1; cytokine-like protein 1"
			}
			]
		},
		{
			"name":"Tumor necrosis fators",
			"children":[
			{
				"name":"104405584 CD40LG; CD40 ligand\tK03161 TNFSF5; tumor necrosis factor ligand superfamily member 5"
			},
			{
				"name":"104406980 tumor necrosis factor ligand superfamily member 6-like\tK04389 TNFSF6; tumor necrosis factor ligand superfamily member 6"
			},
			{
				"name":"104407830 FASLG; tumor necrosis factor ligand superfamily member 6\tK04389 TNFSF6; tumor necrosis factor ligand superfamily member 6"
			},
			{
				"name":"104408492 tumor necrosis factor ligand superfamily member 8-like\tK05471 TNFSF8; tumor necrosis factor ligand superfamily member 8"
			},
			{
				"name":"104408595 LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 10-like\tK04721 TNFSF10; tumor necrosis factor ligand superfamily member 10"
			},
			{
				"name":"104411387 TNFSF11; tumor necrosis factor ligand superfamily member 11\tK05473 TNFSF11; tumor necrosis factor ligand superfamily member 11"
			},
			{
				"name":"104407862 TNFSF13B; tumor necrosis factor ligand superfamily member 13B\tK05476 TNFSF13B; tumor necrosis factor ligand superfamily member 13B"
			},
			{
				"name":"104402391 TNFSF15; tumor necrosis factor ligand superfamily member 15\tK05478 TNFSF15; tumor necrosis factor ligand superfamily member 15"
			},
			{
				"name":"104402371 EDA; ectodysplasin-A\tK05480 EDA; ectodysplasin-A"
			}
			]
		},
		{
			"name":"Transforming growth factors (RSTK binding)",
			"children":[
			{
				"name":"104408091 TGFB2; transforming growth factor beta-2 isoform X1\tK13376 TGFB2; transforming growth factor beta-2"
			},
			{
				"name":"104411056 TGFB3; transforming growth factor beta-3\tK13377 TGFB3; transforming growth factor beta-3"
			},
			{
				"name":"104403325 bone morphogenetic protein 7-like\tK21283 BMP2; bone morphogenetic protein 2"
			},
			{
				"name":"104405183 BMP2; bone morphogenetic protein 2\tK21283 BMP2; bone morphogenetic protein 2"
			},
			{
				"name":"104406031 BMP3; bone morphogenetic protein 3\tK05496 BMP3; bone morphogenetic protein 3"
			},
			{
				"name":"104409245 bone morphogenetic protein 5\tK04663 BMP5; bone morphogenetic protein 5"
			},
			{
				"name":"104402350 BMP6; bone morphogenetic protein 6\tK16620 BMP6; bone morphogenetic protein 6"
			},
			{
				"name":"104410928 BMP7; bone morphogenetic protein 7\tK16621 BMP7; bone morphogenetic protein 7"
			},
			{
				"name":"104406467 BMP10; bone morphogenetic protein 10\tK22670 BMP10; bone morphogenetic protein 10"
			},
			{
				"name":"104399218 BMP15; bone morphogenetic protein 15\tK05498 BMP15; bone morphogenetic protein 15"
			},
			{
				"name":"104407938 GDF1; embryonic growth\/differentiation factor 1\tK05495 GDF1; growth differentiation factor 1"
			},
			{
				"name":"104403226 GDF2; growth\/differentiation factor 2\tK05503 GDF2; growth differentiation factor 2"
			},
			{
				"name":"104399292 GDF5; growth\/differentiation factor 5\tK04664 GDF5; growth differentiation factor 5"
			},
			{
				"name":"104411511 MSTN; growth\/differentiation factor 8 isoform X1\tK05497 MSTN; growth differentiation factor 8"
			},
			{
				"name":"104399012 GDF9; growth\/differentiation factor 9\tK22673 GDF9; growth differentiation factor 9"
			},
			{
				"name":"104408909 GDF10; bone morphogenetic protein 3B\tK22674 GDF10; growth differentiation factor 10"
			},
			{
				"name":"104406885 growth\/differentiation factor 11-like\tK22679 GDF11; growth differentiation factor 11"
			},
			{
				"name":"104403613 nodal homolog\tK04666 NODAL; nodal"
			},
			{
				"name":"104413040 INHA; inhibin alpha chain\tK05500 INHA; inhibin, alpha"
			},
			{
				"name":"104410225 INHBA; inhibin beta A chain\tK04667 INHBA; inhibin beta A chain"
			},
			{
				"name":"104411480 INHBB; inhibin beta B chain\tK22687 INHBB; inhibin beta B chain"
			},
			{
				"name":"104401876 INHBC; inhibin beta C chain\tK22688 INHBC; inhibin beta C chain"
			},
			{
				"name":"104410450 inhibin beta C chain-like\tK22689 INHBE; inhibin beta E chain"
			},
			{
				"name":"104405664 left-right determination factor 1-like\tK04668 LEFTY; left-right determination factor"
			}
			]
		},
		{
			"name":"Growth factors (RTK binding)",
			"children":[
			{
				"name":"104401729 PDGFA; platelet-derived growth factor subunit A\tK04359 PDGFA; platelet-derived growth factor subunit A"
			},
			{
				"name":"104404911 PDGFB; LOW QUALITY PROTEIN: platelet-derived growth factor subunit B\tK17386 PDGFB; platelet-derived growth factor subunit B"
			},
			{
				"name":"104408848 PDGFD; platelet-derived growth factor D\tK05450 PDGFC_D; platelet derived growth factor C\/D"
			},
			{
				"name":"104410372 PDGFC; platelet-derived growth factor C\tK05450 PDGFC_D; platelet derived growth factor C\/D"
			},
			{
				"name":"104404672 VEGFA; vascular endothelial growth factor A\tK05448 VEGFA; vascular endothelial growth factor A"
			},
			{
				"name":"104400737 VEGFC; vascular endothelial growth factor C\tK05449 VEGFC_D; vascular endothelial growth factor C\/D"
			},
			{
				"name":"104402582 FIGF; vascular endothelial growth factor D\tK05449 VEGFC_D; vascular endothelial growth factor C\/D"
			},
			{
				"name":"104401121 PGF; placenta growth factor\tK16859 PGF; placenta growth factor"
			},
			{
				"name":"104402506 NGF; beta-nerve growth factor\tK02582 NGFB; nerve growth factor, beta"
			},
			{
				"name":"104409804 NTF3; neurotrophin-3 isoform X1\tK04356 NTF3; neurotrophin 3"
			},
			{
				"name":"104409217 BDNF; brain-derived neurotrophic factor\tK04355 BDNF; brain-derived neurotrophic factor"
			},
			{
				"name":"104413377 GDNF; glial cell line-derived neurotrophic factor isoform X1\tK05452 GDNF; glial cell derived neurotrophic factor"
			},
			{
				"name":"104408101 FGF1; fibroblast growth factor 1 isoform X1\tK18496 FGF1; fibroblast growth factor 1"
			},
			{
				"name":"104401254 fibroblast growth factor 2-like\tK18497 FGF2; fibroblast growth factor 2"
			},
			{
				"name":"104399345 FGF20; fibroblast growth factor 20\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"104401387 fibroblast growth factor 10-like\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"104402600 FGF8; fibroblast growth factor 8\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"104405205 fibroblast growth factor 9\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"104409010 FGF16; fibroblast growth factor 16\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"104409260 FGF6; fibroblast growth factor 6\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"104412481 FGF3; fibroblast growth factor 3\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"104409837 FGF13; fibroblast growth factor 13\tK22413 FGF11_12_13; fibroblast growth factor 11\/12\/13"
			},
			{
				"name":"104404380 FGF14; fibroblast growth factor 14 isoform X1\tK23920 FGF14; fibroblast growth factor 14"
			},
			{
				"name":"104409455 FGF23; fibroblast growth factor 23\tK22428 FGF23; fibroblast growth factor 23"
			},
			{
				"name":"104402171 NRG1; pro-neuregulin-1, membrane-bound isoform isoform X1\tK05455 NRG1; neuregulin 1"
			},
			{
				"name":"104410362 NRG2; pro-neuregulin-2, membrane-bound isoform\tK05456 NRG2; neuregulin 2"
			},
			{
				"name":"104403402 NRG4; pro-neuregulin-4, membrane-bound isoform\tK05458 NRG4; neuregulin 4"
			},
			{
				"name":"104412813 IGF1; LOW QUALITY PROTEIN: insulin-like growth factor I\tK05459 IGF1; insulin-like growth factor 1"
			},
			{
				"name":"104411430 IGF2; insulin-like growth factor II\tK13769 IGF2; insulin-like growth factor 2"
			},
			{
				"name":"104409459 hepatocyte growth factor-like\tK05460 HGF; hepatocyte growth factor"
			},
			{
				"name":"104402574 TGFA; protransforming growth factor alpha\tK08774 TGFA; transforming growth factor, alpha"
			},
			{
				"name":"104413471 EREG; proepiregulin\tK09784 EREG; epiregulin"
			},
			{
				"name":"104400669 AREG; amphiregulin\tK09782 AREG; amphiregulin"
			},
			{
				"name":"104404453 KITLG; kit ligand\tK05461 KITLG; KIT ligand"
			},
			{
				"name":"104408426 EFNA5; ephrin-A5\tK05462 EFNA; ephrin-A"
			},
			{
				"name":"104410066 EFNA2; ephrin-A2\tK05462 EFNA; ephrin-A"
			},
			{
				"name":"104413618 EFNB2; LOW QUALITY PROTEIN: ephrin-B2\tK05463 EFNB; ephrin-B"
			},
			{
				"name":"104413750 GAS6; growth arrest-specific protein 6\tK05464 GAS6; growth arrest-specific 6"
			},
			{
				"name":"104409207 ANGPT2; angiopoietin-2 isoform X1\tK05466 ANGPT2; angiopoietin 2"
			}
			]
		}
		]
	},
	{
		"name":"Neuropeptides",
		"children":[
		{
			"name":"GPCR binding",
			"children":[
			{
				"name":"104404820 AGT; angiotensinogen\tK09821 AGT; angiotensinogen"
			},
			{
				"name":"104402701 KNG1; kininogen-1\tK03898 KNG; kininogen"
			},
			{
				"name":"104405270 NTS; neurotensin\/neuromedin N\tK05235 NTS; neurotensin"
			},
			{
				"name":"104406690 GRP; gastrin-releasing peptide\tK05224 GRP; gastrin-releasing peptide"
			},
			{
				"name":"104401137 CCK; cholecystokinin\tK05226 CCK; cholecystokinin"
			},
			{
				"name":"104412360 EDN1; endothelin-1\tK16366 EDN1; endothelin-1"
			},
			{
				"name":"104402063 endothelin-2-like\tK16367 EDN2; endothelin-2"
			},
			{
				"name":"104406159 GAL; galanin peptides isoform X1\tK05244 GAL; galanin"
			},
			{
				"name":"104405189 SPX; spexin\tK25694 SPX; spexin"
			},
			{
				"name":"104402466 GHRL; LOW QUALITY PROTEIN: appetite-regulating hormone\tK05254 GHRL; ghrelin"
			},
			{
				"name":"104402591 NMU; neuromedin-U\tK05249 NMU; neuromedin U"
			},
			{
				"name":"104403159 NPVF; pro-FMRFamide-related neuropeptide VF\tK25692 NPVF; pro-FMRFamide-related neuropeptide VF"
			},
			{
				"name":"104411793 NPS; LOW QUALITY PROTEIN: neuropeptide S\tK25691 NPS; neuropeptide S"
			},
			{
				"name":"104400873 NPY; pro-neuropeptide Y\tK05232 NPY; neuropeptide Y"
			},
			{
				"name":"104405822 POMC; LOW QUALITY PROTEIN: pro-opiomelanocortin\tK05228 POMC; proopiomelanocortin"
			},
			{
				"name":"104401196 PENK; proenkephalin-A\tK18832 PENK; proenkephalin A"
			},
			{
				"name":"104399411 OXT; oxytocin-neurophysin 1\tK05243 OXT; oxytocin-neurophysin 1"
			},
			{
				"name":"104409971 SST; somatostatin\tK05237 SST; somatostatin"
			},
			{
				"name":"104399420 somatostatin-2-like\tK05238 CORT; cortistatin"
			},
			{
				"name":"104412817 TAC1; protachykinin-1\tK05239 TAC1; tachykinin 1"
			},
			{
				"name":"104411842 UTS2; urotensin-2\tK05248 UTS2; urotensin 2"
			},
			{
				"name":"104400995 UTS2B; urotensin-2B isoform X1\tK24267 UTS2B; urotensin-2B"
			},
			{
				"name":"104402925 PRLH; prolactin-releasing peptide\tK05269 PRH; prolactin-releasing peptide"
			},
			{
				"name":"104410874 CHGA; chromogranin-A\tK19990 CHGA; chromogranin-A"
			},
			{
				"name":"104401298 CHGB; secretogranin-1\tK19991 CHGB; chromogranin-B"
			},
			{
				"name":"104404875 SCG2; secretogranin-2\tK25732 SCG2; secretogranin-2"
			},
			{
				"name":"104407432 SCG3; secretogranin-3 isoform X1\tK25733 SCG3; secretogranin-3"
			},
			{
				"name":"104400485 SCG5; neuroendocrine protein 7B2\tK25734 SCG5; neuroendocrine protein 7B2"
			},
			{
				"name":"104413188 GNRH1; progonadoliberin-1\tK05252 GNRH; gonadotropin-releasing hormone"
			},
			{
				"name":"104400619 TRH; thyrotropin releasing hormone\tK05253 TRH; thyrotropin-releasing hormone"
			},
			{
				"name":"104408666 INSL5; insulin-like peptide INSL5\tK22001 INSL5; insulin-like 5"
			},
			{
				"name":"104403083 PMCH; pro-MCH\tK05229 PMCH; pro-melanin-concentrating hormone"
			},
			{
				"name":"104413427 CALCB; calcitonin gene-related peptide 2 isoform X1\tK12332 CALC; calcitonin"
			},
			{
				"name":"104409987 IAPP; islet amyloid polypeptide\tK08039 IAPP; islet amyloid polypeptide"
			},
			{
				"name":"104408310 UCN3; urocortin-3\tK05257 UCN2_3; urocortin 2\/3"
			},
			{
				"name":"104399413 GIP; gastric inhibitory polypeptide\tK05258 GIP; gastric inhibitory polypeptide"
			},
			{
				"name":"104400746 GCG; glucagon\tK05259 GCG; glucagon"
			},
			{
				"name":"104399469 PTH; parathyroid hormone\tK05261 PTH; parathyroid hormone"
			},
			{
				"name":"104412277 VIP peptides\tK05264 VIP; vasoactive intestinal peptide"
			},
			{
				"name":"104405668 PTHLH; parathyroid hormone-related protein\tK22608 PTHLH; parathyroid hormone-related hormone"
			},
			{
				"name":"104409954 CGA; glycoprotein hormones alpha chain\tK08522 CGA; glycoprotein hormones alpha chain"
			},
			{
				"name":"104402486 FSHB; follitropin subunit beta\tK05250 FSHB; follitropin subunit beta"
			},
			{
				"name":"104410855 TSHB; thyrotropin subunit beta\tK05251 TSHB; thyrotropin subunit beta"
			},
			{
				"name":"104403422 GPHB5; glycoprotein hormone beta-5\tK25484 GPHB5; glycoprotein hormone beta-5"
			}
			]
		},
		{
			"name":"Unclassified",
			"children":[
			{
				"name":"104409375 natriuretic peptides A\tK12334 NPPA; natriuretic peptide A"
			},
			{
				"name":"104402948 C-type natriuretic peptide 2-like\tK12336 NPPC; natriuretic peptide C"
			},
			{
				"name":"104404387 NPPC; C-type natriuretic peptide\tK12336 NPPC; natriuretic peptide C"
			},
			{
				"name":"104405419 NXPH1; neurexophilin-1\tK16656 NXPH1; neurexophilin-1"
			},
			{
				"name":"104408437 NXPH2; neurexophilin-2\tK16657 NXPH2; neurexophilin-2"
			},
			{
				"name":"104412246 NXPH3; neurexophilin-3\tK16658 NXPH3; neurexophilin-3"
			},
			{
				"name":"104404955 INS; insulin\tK04526 INS; insulin"
			},
			{
				"name":"104401064 PRL; prolactin\tK05439 PRL; prolactin"
			},
			{
				"name":"104403085 AGRP; agouti-related protein\tK05231 AGRP; agouti related protein"
			},
			{
				"name":"104411819 acyl-CoA-binding protein-like\tK08762 DBI; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)"
			},
			{
				"name":"104401753 CBLN4; cerebellin-4\tK24235 CBLN; cerebellin"
			},
			{
				"name":"104407902 CBLN2; cerebellin-2\tK24235 CBLN; cerebellin"
			},
			{
				"name":"104404934 adiponectin-like\tK07296 ADIPOQ; adiponectin"
			},
			{
				"name":"104413433 NAMPT; nicotinamide phosphoribosyltransferase\tK03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]"
			},
			{
				"name":"104409917 NUCB2; nucleobindin-2\tK20371 NUCB; nucleobindin"
			}
			]
		}
		]
	}
	]
}