{
	"name":"npe01002",
	"children":[
	{
		"name":"Aspartic peptidases",
		"children":[
		{
			"name":"Family A1: pepsin family"
		},
		{
			"name":"Family A2: retropepsin family"
		},
		{
			"name":"Family A5: thermopsin family"
		},
		{
			"name":"Family A8: signal peptidase II family"
		},
		{
			"name":"Family A22: presenilin family",
			"children":[
			{
				"name":"Natpe_2300 hypothetical protein\tK28485 psh1; intramembrane aspartyl peptidase"
			}
			]
		},
		{
			"name":"Family A24: type IV prepilin peptidase family",
			"children":[
			{
				"name":"Natpe_0069 leader peptidase family protein\tK07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]"
			}
			]
		},
		{
			"name":"Family A25: gpr protease family"
		},
		{
			"name":"Family A26: omptin family"
		},
		{
			"name":"Family A28"
		},
		{
			"name":"Family A31: HybD endopeptidase family"
		},
		{
			"name":"Family A36"
		}
		]
	},
	{
		"name":"Cysteine peptidases",
		"children":[
		{
			"name":"Family C1: papain family"
		},
		{
			"name":"Family C2: calpain family"
		},
		{
			"name":"Family C3: picornain family"
		},
		{
			"name":"Family C4: NIa protease family"
		},
		{
			"name":"Family C5"
		},
		{
			"name":"Family C9"
		},
		{
			"name":"Family C10: streptopain family"
		},
		{
			"name":"Family C11: clostripain family"
		},
		{
			"name":"Family C12: ubiquitin C-terminal hydrolase family"
		},
		{
			"name":"Family C13: legumain family"
		},
		{
			"name":"Family C14: caspase family"
		},
		{
			"name":"Family C15: pyroglutamyl peptidase I family"
		},
		{
			"name":"Family C16"
		},
		{
			"name":"Family C19: ubiquitin-specific protease family"
		},
		{
			"name":"Family C25: gingipain family"
		},
		{
			"name":"Family C26: gamma-glutamyl hydrolase family",
			"children":[
			{
				"name":"Natpe_0022 GMP synthase family protein\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
			},
			{
				"name":"Natpe_2970 GMP synthase, glutamine-hydrolyzing, N-terminal domain or A subunit\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
			},
			{
				"name":"Natpe_3342 GMP synthase, glutamine-hydrolyzing, C-terminal domain or B subunit\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
			}
			]
		},
		{
			"name":"Family C27"
		},
		{
			"name":"Family C30"
		},
		{
			"name":"Family C37"
		},
		{
			"name":"Family C39"
		},
		{
			"name":"Family C40"
		},
		{
			"name":"Family C44",
			"children":[
			{
				"name":"Natpe_1392 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
			},
			{
				"name":"Natpe_0471 glutamate synthase family protein\tK00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]"
			},
			{
				"name":"Natpe_1269 glucosamine--fructose-6-phosphate aminotransferase, isomerizing\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
			},
			{
				"name":"Natpe_3025 glucosamine--fructose-6-phosphate aminotransferase, isomerizing\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
			},
			{
				"name":"Natpe_2388 asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
			}
			]
		},
		{
			"name":"Family C45"
		},
		{
			"name":"Family C46: hedgehog family"
		},
		{
			"name":"Family C47: staphopain family"
		},
		{
			"name":"Family C48: Ulp1 endopeptidase family"
		},
		{
			"name":"Family C50: separase family"
		},
		{
			"name":"Family C54: Aut2 peptidase family"
		},
		{
			"name":"Family C55: YopJ protease family"
		},
		{
			"name":"Family C56: PfpI endopeptidase family",
			"children":[
			{
				"name":"Natpe_2120 intracellular protease, PfpI family\tK05520 yhbO; deglycase [EC:3.5.1.124]"
			}
			]
		},
		{
			"name":"Family C57: vaccinia virus I7 peptidase family"
		},
		{
			"name":"Family C58"
		},
		{
			"name":"Family C59"
		},
		{
			"name":"Family C60",
			"children":[
			{
				"name":"Natpe_2989 putative membrane protein\tK24447 artA; archaeosortase A [EC:3.4.22.-]"
			}
			]
		},
		{
			"name":"Family C63"
		},
		{
			"name":"Family C64"
		},
		{
			"name":"Family C65"
		},
		{
			"name":"Family C67"
		},
		{
			"name":"Family C69"
		},
		{
			"name":"Family C70"
		},
		{
			"name":"Family C75"
		},
		{
			"name":"Family C76"
		},
		{
			"name":"Family C78"
		},
		{
			"name":"Family C79"
		},
		{
			"name":"Family C82"
		},
		{
			"name":"Family C83"
		},
		{
			"name":"Family C85"
		},
		{
			"name":"Family C86"
		},
		{
			"name":"Family C88"
		},
		{
			"name":"Family C89"
		},
		{
			"name":"Family C97"
		},
		{
			"name":"Family C98"
		},
		{
			"name":"Family C110"
		}
		]
	},
	{
		"name":"Glutamic peptidases",
		"children":[
		{
			"name":"Family G1"
		},
		{
			"name":"Family G4"
		},
		{
			"name":"Family G5: prenyl protease 2 family",
			"children":[
			{
				"name":"Natpe_0131 putative metal-dependent membrane protease\tK07052 K07052; CAAX protease family protein"
			},
			{
				"name":"Natpe_3201 putative metal-dependent membrane protease\tK07052 K07052; CAAX protease family protein"
			},
			{
				"name":"Natpe_3334 putative metal-dependent membrane protease\tK07052 K07052; CAAX protease family protein"
			}
			]
		}
		]
	},
	{
		"name":"Metallo peptidases",
		"children":[
		{
			"name":"Family M1"
		},
		{
			"name":"Family M2"
		},
		{
			"name":"Family M3",
			"children":[
			{
				"name":"Natpe_0358 oligoendopeptidase F\tK08602 pepF; oligoendopeptidase F [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M4: thermolysin family"
		},
		{
			"name":"Family M5: mycolysin family"
		},
		{
			"name":"Family M6: immune inhibitor A family"
		},
		{
			"name":"Family M7: snapalysin family"
		},
		{
			"name":"Family M8: leishmanolysin family"
		},
		{
			"name":"Family M9"
		},
		{
			"name":"Family M10"
		},
		{
			"name":"Family M12: astacin\/adamalysin family"
		},
		{
			"name":"Family M13: neprilysin family"
		},
		{
			"name":"Family M14: carboxypeptidase A family"
		},
		{
			"name":"Family M15: zinc D-Ala-D-Ala carboxypeptidase family"
		},
		{
			"name":"Family M16: pitrilysin family"
		},
		{
			"name":"Family M17: leucyl aminopeptidase family"
		},
		{
			"name":"Family M18"
		},
		{
			"name":"Family M19: membrane dipeptidase family"
		},
		{
			"name":"Family M20",
			"children":[
			{
				"name":"Natpe_3216 acetylornithine deacetylase\/succinyldiaminopimelate desuccinylase-like deacylase\tK01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]"
			},
			{
				"name":"Natpe_0770 amidohydrolase\tK12940 abgA; aminobenzoyl-glutamate utilization protein A"
			},
			{
				"name":"Natpe_0781 amidohydrolase\tK12940 abgA; aminobenzoyl-glutamate utilization protein A"
			},
			{
				"name":"Natpe_3241 amidohydrolase\tK12940 abgA; aminobenzoyl-glutamate utilization protein A"
			}
			]
		},
		{
			"name":"Family M23"
		},
		{
			"name":"Family M24",
			"children":[
			{
				"name":"Natpe_3470 methionine aminopeptidase, type II\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
			},
			{
				"name":"Natpe_2943 Xaa-Pro aminopeptidase\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
			}
			]
		},
		{
			"name":"Family M26"
		},
		{
			"name":"Family M27"
		},
		{
			"name":"Family M28: aminopeptidase Y family"
		},
		{
			"name":"Family M29: aminopeptidase T family",
			"children":[
			{
				"name":"Natpe_3420 leucyl aminopeptidase (aminopeptidase T)\tK19689 ampS; aminopeptidase [EC:3.4.11.-]"
			},
			{
				"name":"Natpe_3703 leucyl aminopeptidase (aminopeptidase T)\tK19689 ampS; aminopeptidase [EC:3.4.11.-]"
			}
			]
		},
		{
			"name":"Family M32: carboxypeptidase Taq family",
			"children":[
			{
				"name":"Natpe_0349 Zn-dependent carboxypeptidase\tK01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]"
			}
			]
		},
		{
			"name":"Family M34: anthrax lethal factor family"
		},
		{
			"name":"Family M35: deuterolysin family"
		},
		{
			"name":"Family M36: fungalysin family"
		},
		{
			"name":"Family M38: beta-aspartyl dipeptidase family"
		},
		{
			"name":"Family M41: FtsH endopeptidase family"
		},
		{
			"name":"Family M42: glutamyl aminopeptidase family"
		},
		{
			"name":"Family M43: cytophagalysin family"
		},
		{
			"name":"Family M44"
		},
		{
			"name":"Family M48: Ste24 endopeptidase family",
			"children":[
			{
				"name":"Natpe_0352 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_2112 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_3075 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_3224 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_3242 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_3743 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_3768 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_4121 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"Natpe_4127 Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M49: dipeptidyl-peptidase III family"
		},
		{
			"name":"Family M50: S2P protease family"
		},
		{
			"name":"Family M54",
			"children":[
			{
				"name":"Natpe_0321 putative Zn-dependent protease\tK06974 amzA; archaemetzincin [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Family M55: DppA aminopeptidase family"
		},
		{
			"name":"Family M56"
		},
		{
			"name":"Family M67",
			"children":[
			{
				"name":"Natpe_0454 putative metal-dependent protease of the PAD1\/JAB1 superfamily\tK20110 JAMM1; desampylase [EC:3.4.19.15]"
			}
			]
		},
		{
			"name":"Family M72"
		},
		{
			"name":"Family M73"
		},
		{
			"name":"Family M74"
		},
		{
			"name":"Family M80"
		},
		{
			"name":"Family M82",
			"children":[
			{
				"name":"Natpe_0407 putative membrane protein\tK24131 prsW; protease PrsW [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Family M85"
		},
		{
			"name":"Family M88"
		},
		{
			"name":"Family M90"
		},
		{
			"name":"Family M98"
		}
		]
	},
	{
		"name":"Asparagine peptide lyases",
		"children":[
		{
			"name":"Family N1"
		},
		{
			"name":"Family N8"
		}
		]
	},
	{
		"name":"Mixed peptidases",
		"children":[
		{
			"name":"Family P1: DmpA aminopeptidase family"
		},
		{
			"name":"Family P2"
		}
		]
	},
	{
		"name":"Serine peptidases",
		"children":[
		{
			"name":"Family S1: chymotrypsin family",
			"children":[
			{
				"name":"Natpe_2056 trypsin-like serine protease with C-terminal PDZ domain\tK04771 degP; serine protease Do [EC:3.4.21.107]"
			}
			]
		},
		{
			"name":"Family S3: togavirin family"
		},
		{
			"name":"Family S6"
		},
		{
			"name":"Family S7: flavivirin family"
		},
		{
			"name":"Family S8: subtilisin family",
			"children":[
			{
				"name":"Natpe_0106 subtilisin-like serine protease\tK01342 aprE; subtilisin [EC:3.4.21.62]"
			},
			{
				"name":"Natpe_1570 subtilisin-like serine protease\tK14645 K14645; serine protease [EC:3.4.21.-]"
			},
			{
				"name":"Natpe_1571 subtilisin-like serine protease\tK14645 K14645; serine protease [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S9: prolyl oligopeptidase family"
		},
		{
			"name":"Family S10"
		},
		{
			"name":"Family S11: D-Ala-D-Ala carboxypeptidase A family"
		},
		{
			"name":"Family S12: D-Ala-D-Ala carboxypeptidase B family"
		},
		{
			"name":"Family S13: D-Ala-D-Ala peptidase C family"
		},
		{
			"name":"Family S14: ClpP endopeptidase family"
		},
		{
			"name":"Family S15"
		},
		{
			"name":"Family S16: lon protease family",
			"children":[
			{
				"name":"Natpe_2934 lon-related putative ATP-dependent protease\tK04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]"
			},
			{
				"name":"Natpe_3202 lon-related putative ATP-dependent protease\tK04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]"
			}
			]
		},
		{
			"name":"Family S21: assemblin family"
		},
		{
			"name":"Family S24: LexA family"
		},
		{
			"name":"Family S26: signal peptidase I family",
			"children":[
			{
				"name":"Natpe_0002 signal peptidase I\tK13280 SEC11; signal peptidase I [EC:3.4.21.89]"
			},
			{
				"name":"Natpe_0003 signal peptidase I\tK13280 SEC11; signal peptidase I [EC:3.4.21.89]"
			},
			{
				"name":"Natpe_0335 signal peptidase I\tK13280 SEC11; signal peptidase I [EC:3.4.21.89]"
			}
			]
		},
		{
			"name":"Family S28"
		},
		{
			"name":"Family S31"
		},
		{
			"name":"Family S32"
		},
		{
			"name":"Family S33"
		},
		{
			"name":"Family S41: C-terminal processing peptidase family"
		},
		{
			"name":"Family S45"
		},
		{
			"name":"Family S49: protease IV family",
			"children":[
			{
				"name":"Natpe_3275 signal peptide peptidase SppA, 36K type\tK04773 sppA; protease IV [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S50"
		},
		{
			"name":"Family S51"
		},
		{
			"name":"Family S53"
		},
		{
			"name":"Family S54: Rhomboid family",
			"children":[
			{
				"name":"Natpe_2337 hypothetical protein\tK28366 rho1; rhomboid family protease [EC:3.4.21.105]"
			},
			{
				"name":"Natpe_2043 putative membrane protein\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]"
			}
			]
		},
		{
			"name":"Family S55: SpoIVB peptidase family"
		},
		{
			"name":"Family S62"
		},
		{
			"name":"Family S66"
		},
		{
			"name":"Family S77: phage prohead processing peptidase family"
		},
		{
			"name":"Family S78"
		}
		]
	},
	{
		"name":"Threonine peptidases",
		"children":[
		{
			"name":"Family T1: proteasome family",
			"children":[
			{
				"name":"Natpe_1510 proteasome endopeptidase complex, archaeal, alpha subunit\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]"
			},
			{
				"name":"Natpe_2518 proteasome endopeptidase complex, archaeal, alpha subunit\tK03432 psmA; proteasome alpha subunit [EC:3.4.25.1]"
			},
			{
				"name":"Natpe_1509 proteasome endopeptidase complex, archaeal, beta subunit\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]"
			},
			{
				"name":"Natpe_2576 proteasome endopeptidase complex, archaeal, beta subunit\tK03433 psmB; proteasome beta subunit [EC:3.4.25.1]"
			}
			]
		},
		{
			"name":"Family T2"
		},
		{
			"name":"Family T3: gamma-glutamyltransferase family"
		}
		]
	},
	{
		"name":"Peptidases of unknown catalytic type",
		"children":[
		{
			"name":"Family U32"
		},
		{
			"name":"Family U62"
		}
		]
	},
	{
		"name":"Peptidase inhibitors",
		"children":[
		{
			"name":"Family I1: Kazal family"
		},
		{
			"name":"Family I2: Kunitz - BPTI family"
		},
		{
			"name":"Family I4: serpin family"
		},
		{
			"name":"Family I11: ecotin family"
		},
		{
			"name":"Family I17: WAP-type family"
		},
		{
			"name":"Family I25: cystatin family"
		},
		{
			"name":"Family I27: calpastatin family"
		},
		{
			"name":"Family I32: IAP family"
		},
		{
			"name":"Family I34: IA3 family"
		},
		{
			"name":"Family I35: timp family"
		},
		{
			"name":"Family I39: alpha2M family"
		},
		{
			"name":"Family I47: latexin family"
		},
		{
			"name":"Family I49: proSAAS family"
		},
		{
			"name":"Family I51: IC family"
		},
		{
			"name":"Family I57: staphostatin B family"
		},
		{
			"name":"Family I63"
		},
		{
			"name":"Family I80"
		},
		{
			"name":"Family I87"
		},
		{
			"name":"Family I93"
		}
		]
	}
	]
}