{
	"name":"obi03021",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"RNA polymerase II system",
			"children":[
			{
				"name":"RNA polymerase II",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"106878530 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
					},
					{
						"name":"106874492 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
					},
					{
						"name":"106879631 DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
					},
					{
						"name":"106874013 DNA-directed RNA polymerase II subunit RPB11-a\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
					}
					]
				},
				{
					"name":"Pol II specific subunits",
					"children":[
					{
						"name":"106876036 DNA-directed RNA polymerase II subunit RPB4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
					},
					{
						"name":"106871620 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"106878968 DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"106874998 DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"106875893 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"106867543 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					}
					]
				},
				{
					"name":"Pol IV and V specific subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIA",
					"children":[
					{
						"name":"106870844 transcription initiation factor IIA subunit 1\tK03122 TFIIA1; transcription initiation factor TFIIA large subunit"
					},
					{
						"name":"106873790 transcription initiation factor IIA subunit 2\tK03123 TFIIA2; transcription initiation factor TFIIA small subunit"
					}
					]
				},
				{
					"name":"TFIIB",
					"children":[
					{
						"name":"106877794 transcription initiation factor IIB\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFIID",
					"children":[
					{
						"name":"106870472 uncharacterized protein LOC106870472\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"106877877 transcription initiation factor TFIID subunit 1 isoform X1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
					},
					{
						"name":"106873886 LOW QUALITY PROTEIN: transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"106875157 transcription initiation factor TFIID subunit 3\tK14650 TAF3; transcription initiation factor TFIID subunit 3"
					},
					{
						"name":"106882896 transcription initiation factor TFIID subunit 4\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"106871336 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"106884287 TAF5-like RNA polymerase II p300\/CBP-associated factor-associated factor 65 kDa subunit 5L\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"106875417 transcription initiation factor TFIID subunit 6\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"106876645 uncharacterized protein LOC106876645 isoform X1\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"106867560 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"106873826 transcription initiation factor TFIID subunit 8\tK14649 TAF8; transcription initiation factor TFIID subunit 8"
					},
					{
						"name":"106873098 transcription initiation factor TFIID subunit 9B\tK14535 TAF9; transcription initiation factor TFIID subunit 9"
					},
					{
						"name":"106883341 transcription initiation factor TFIID subunit 10 isoform X1\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"106882688 transcription initiation factor TFIID subunit 11\tK03135 TAF11; transcription initiation factor TFIID subunit 11"
					},
					{
						"name":"106874819 transcription initiation factor TFIID subunit 12\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"106873646 transcription initiation factor TFIID subunit 13 isoform X2\tK03127 TAF13; transcription initiation factor TFIID subunit 13"
					}
					]
				},
				{
					"name":"TFIIE",
					"children":[
					{
						"name":"106883880 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					},
					{
						"name":"106868283 transcription initiation factor IIE subunit beta\tK03137 TFIIE2; transcription initiation factor TFIIE subunit beta"
					}
					]
				},
				{
					"name":"TFIIF",
					"children":[
					{
						"name":"106881049 general transcription factor IIF subunit 1\tK03138 TFIIF1; transcription initiation factor TFIIF subunit alpha"
					},
					{
						"name":"106882034 general transcription factor IIF subunit 2\tK03139 TFIIF2; transcription initiation factor TFIIF subunit beta [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"TFIIH",
					"children":[
					{
						"name":"106872060 general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"106875921 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"106870275 general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"106879324 general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"106882049 general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"106868561 general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"106883163 cyclin-dependent kinase 7 isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"106873812 CDK-activating kinase assembly factor MAT1 isoform X1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					},
					{
						"name":"106879470 cyclin-H isoform X1\tK06634 CCNH; cyclin H"
					}
					]
				}
				]
			},
			{
				"name":"Mediator complex",
				"children":[
				{
					"name":"Head",
					"children":[
					{
						"name":"106879940 mediator of RNA polymerase II transcription subunit 6 isoform X1\tK15128 MED6; mediator of RNA polymerase II transcription subunit 6"
					},
					{
						"name":"106871197 mediator of RNA polymerase II transcription subunit 8 isoform X1\tK15129 MED8; mediator of RNA polymerase II transcription subunit 8"
					},
					{
						"name":"106884384 mediator of RNA polymerase II transcription subunit 11\tK15131 MED11; mediator of RNA polymerase II transcription subunit 11"
					},
					{
						"name":"106873745 mediator of RNA polymerase II transcription subunit 17\tK15133 MED17; mediator of RNA polymerase II transcription subunit 17"
					},
					{
						"name":"106883204 mediator of RNA polymerase II transcription subunit 18\tK15135 MED18; mediator of RNA polymerase II transcription subunit 18"
					},
					{
						"name":"106879148 mediator of RNA polymerase II transcription subunit 19\tK15137 MED19; mediator of RNA polymerase II transcription subunit 19"
					},
					{
						"name":"106883613 mediator of RNA polymerase II transcription subunit 20\tK13528 MED20; mediator of RNA polymerase II transcription subunit 20"
					},
					{
						"name":"106877273 mediator of RNA polymerase II transcription subunit 22 isoform X1\tK15139 MED22; mediator of RNA polymerase II transcription subunit 22"
					},
					{
						"name":"106878893 mediator of RNA polymerase II transcription subunit 28\tK15141 MED28; mediator of RNA polymerase II transcription subunit 28"
					},
					{
						"name":"106879289 mediator of RNA polymerase II transcription subunit 29\tK15142 MED29; mediator of RNA polymerase II transcription subunit 29"
					},
					{
						"name":"106873975 mediator of RNA polymerase II transcription subunit 30\tK15143 MED30; mediator of RNA polymerase II transcription subunit 30"
					}
					]
				},
				{
					"name":"Middle",
					"children":[
					{
						"name":"106877818 mediator of RNA polymerase II transcription subunit 4\tK15146 MED4; mediator of RNA polymerase II transcription subunit 4"
					},
					{
						"name":"106877723 mediator of RNA polymerase II transcription subunit 7\tK15148 MED7; mediator of RNA polymerase II transcription subunit 7"
					},
					{
						"name":"106870036 mediator of RNA polymerase II transcription subunit 9\tK15149 MED9; mediator of RNA polymerase II transcription subunit 9"
					},
					{
						"name":"106882862 mediator of RNA polymerase II transcription subunit 10\tK15151 MED10; mediator of RNA polymerase II transcription subunit 10"
					},
					{
						"name":"106882997 mediator of RNA polymerase II transcription subunit 21\tK15152 MED21; mediator of RNA polymerase II transcription subunit 21"
					},
					{
						"name":"106881139 mediator of RNA polymerase II transcription subunit 31\tK15153 MED31; mediator of RNA polymerase II transcription subunit 31"
					}
					]
				},
				{
					"name":"Tail",
					"children":[
					{
						"name":"106871902 mediator of RNA polymerase II transcription subunit 14\tK15156 MED14; mediator of RNA polymerase II transcription subunit 14"
					},
					{
						"name":"106872996 mediator of RNA polymerase II transcription subunit 15 isoform X1\tK15157 MED15; mediator of RNA polymerase II transcription subunit 15"
					},
					{
						"name":"106879282 mediator of RNA polymerase II transcription subunit 16\tK15159 MED16; mediator of RNA polymerase II transcription subunit 16"
					}
					]
				},
				{
					"name":"CDK-module",
					"children":[
					{
						"name":"106878348 LOW QUALITY PROTEIN: cyclin-dependent kinase 8-like\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"106867551 cyclin-C\tK15161 CCNC; cyclin-C"
					},
					{
						"name":"106884372 mediator of RNA polymerase II transcription subunit 12\tK15162 MED12; mediator of RNA polymerase II transcription subunit 12"
					},
					{
						"name":"106869075 mediator of RNA polymerase II transcription subunit 13-like isoform X1\tK15164 MED13; mediator of RNA polymerase II transcription subunit 13"
					}
					]
				},
				{
					"name":"Other mediators",
					"children":[
					{
						"name":"106880566 mediator of RNA polymerase II transcription subunit 23\tK15166 MED23; mediator of RNA polymerase II transcription subunit 23"
					},
					{
						"name":"106884416 mediator of RNA polymerase II transcription subunit 24 isoform X1\tK15167 MED24; mediator of RNA polymerase II transcription subunit 24"
					},
					{
						"name":"106884453 putative uncharacterized protein DDB_G0271606 isoform X1\tK15168 MED25; mediator of RNA polymerase II transcription subunit 25"
					},
					{
						"name":"106868293 mediator of RNA polymerase II transcription subunit 26 isoform X1\tK15169 MED26; mediator of RNA polymerase II transcription subunit 26"
					},
					{
						"name":"106882650 mediator of RNA polymerase II transcription subunit 27\tK15170 MED27; mediator of RNA polymerase II transcription subunit 27"
					}
					]
				}
				]
			},
			{
				"name":"Coactivators",
				"children":[
				{
					"name":"SAGA\/TFTC\/STAGA complex",
					"children":[
					{
						"name":"106871034 histone acetyltransferase KAT2A isoform X1\tK06062 PCAF; histone acetyltransferase [EC:2.3.1.48]"
					},
					{
						"name":"106869568 transformation\/transcription domain-associated protein\tK08874 TRRAP; transformation\/transcription domain-associated protein"
					},
					{
						"name":"106871147 transcription initiation protein SPT3 homolog\tK11313 SUPT3H; transcription initiation protein SPT3"
					},
					{
						"name":"106870270 transcriptional adapter 2-alpha\tK11314 TADA2A; transcriptional adapter 2-alpha"
					},
					{
						"name":"106877080 transcriptional adapter 2-beta isoform X1\tK15127 TADA2B; transcriptional adapter 2-beta"
					},
					{
						"name":"106882183 transcriptional adapter 2-beta\tK15127 TADA2B; transcriptional adapter 2-beta"
					},
					{
						"name":"106868587 transcriptional adapter 3 isoform X1\tK11315 TADA3; transcriptional adapter 3"
					},
					{
						"name":"106875265 transcriptional adapter 1 isoform X1\tK11317 TADA1; transcriptional adapter 1"
					},
					{
						"name":"106873886 LOW QUALITY PROTEIN: transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"106882896 transcription initiation factor TFIID subunit 4\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"106871336 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"106884287 TAF5-like RNA polymerase II p300\/CBP-associated factor-associated factor 65 kDa subunit 5L\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"106875417 transcription initiation factor TFIID subunit 6\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"106876645 uncharacterized protein LOC106876645 isoform X1\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"106867560 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"106873098 transcription initiation factor TFIID subunit 9B\tK14535 TAF9; transcription initiation factor TFIID subunit 9"
					},
					{
						"name":"106883341 transcription initiation factor TFIID subunit 10 isoform X1\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"106874819 transcription initiation factor TFIID subunit 12\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"106877361 ataxin-7-like protein 3 isoform X3\tK11363 ATXN7L; SAGA-associated factor 11"
					},
					{
						"name":"106867454 SAGA-associated factor 29\tK11364 SGF29; SAGA-associated factor 29"
					},
					{
						"name":"106881885 STAGA complex 65 subunit gamma\tK11316 SUPT7L; STAGA complex 65 subunit gamma"
					},
					{
						"name":"106879099 transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"106880935 ubiquitin carboxyl-terminal hydrolase 22 isoform X1\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
					},
					{
						"name":"106867716 splicing factor 3B subunit 3\tK12830 SF3B3; splicing factor 3B subunit 3"
					}
					]
				},
				{
					"name":"BAF\/PBAF complex",
					"children":[
					{
						"name":"106881555 probable global transcription activator SNF2L2 isoform X1\tK11647 SMARCA2_4; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2\/4 [EC:5.6.2.-]"
					},
					{
						"name":"106868974 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"106871460 SWI\/SNF complex subunit SMARCC1 isoform X1\tK11649 SMARCC; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C"
					},
					{
						"name":"106869145 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform X1\tK11650 SMARCD; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D"
					},
					{
						"name":"106878467 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1\tK11651 SMARCE1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1"
					},
					{
						"name":"106867064 actin, cytoplasmic\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106870394 actin, adductor muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106875747 actin, adductor muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106879182 actin, cytoplasmic 2 isoform X1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106871757 actin-like protein 6B\tK11652 ACTL6B; actin-like protein 6B"
					},
					{
						"name":"106883893 AT-rich interactive domain-containing protein 1B isoform X1\tK11653 ARID1; AT-rich interactive domain-containing protein 1"
					},
					{
						"name":"106876167 AT-rich interactive domain-containing protein 2 isoform X1\tK11765 ARID2; AT-rich interactive domain-containing protein 2"
					},
					{
						"name":"106870580 protein polybromo-1\tK11757 PBRM1; protein polybromo-1"
					}
					]
				},
				{
					"name":"SWI\/SNF complex",
					"children":[
					{
						"name":"106868974 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					}
					]
				},
				{
					"name":"RSC complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"106871243 cell division cycle and apoptosis regulator protein 1\tK25827 CCAR1; cell division cycle and apoptosis regulator protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"106869012 transcription elongation factor A protein 1\tK03145 TFIIS; transcription elongation factor S-II"
					},
					{
						"name":"106869069 transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"106881540 transcription elongation factor SPT5 isoform X1\tK15172 SUPT5H; transcription elongation factor SPT5"
					},
					{
						"name":"106881379 transcription elongation factor SPT6\tK11292 SUPT6H; transcription elongation factor SPT6"
					}
					]
				},
				{
					"name":"Transcription termination factor",
					"children":[
					{
						"name":"106874552 transcription termination factor 2\tK15173 TTF2; transcription termination factor 2 [EC:5.6.2.-]"
					},
					{
						"name":"106872667 pre-mRNA cleavage complex 2 protein Pcf11 isoform X1\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					},
					{
						"name":"106871560 cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"106876794 cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"106867798 cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"106868130 uncharacterized protein LOC106868130\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106871374 serine\/threonine-protein phosphatase alpha-2 isoform isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106873168 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase PP1-beta catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106875137 symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"106877625 RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"106869156 5'-3' exoribonuclease 2\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"106868628 decapping and exoribonuclease protein\tK14845 RAI1; RAT1-interacting protein"
					},
					{
						"name":"106879632 regulation of nuclear pre-mRNA domain-containing protein 1B\tK15559 RTT103; regulator of Ty1 transposition protein 103"
					},
					{
						"name":"106881973 non-POU domain-containing octamer-binding protein\tK13219 SFPQ; splicing factor, proline- and glutamine-rich"
					},
					{
						"name":"106873142 SR-related and CTD-associated factor 4\tK13191 RBM16; RNA-binding protein 16"
					},
					{
						"name":"106869321 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1\tK09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"
					}
					]
				},
				{
					"name":"PAF1 complex",
					"children":[
					{
						"name":"106879593 RNA polymerase II-associated factor 1 homolog\tK15174 PAF1; RNA polymerase II-associated factor 1"
					},
					{
						"name":"106881307 parafibromin\tK15175 CDC73; parafibromin"
					},
					{
						"name":"106877440 RNA polymerase-associated protein CTR9 homolog\tK15176 CTR9; RNA polymerase-associated protein CTR9"
					},
					{
						"name":"106873747 RNA polymerase-associated protein LEO1\tK15177 LEO1; RNA polymerase-associated protein LEO1"
					},
					{
						"name":"106872109 RNA polymerase-associated protein RTF1 homolog\tK15178 RTF1; RNA polymerase-associated protein RTF1"
					}
					]
				},
				{
					"name":"NELF complex",
					"children":[
					{
						"name":"106874145 negative elongation factor A\tK15179 WHSC2; negative elongation factor A"
					},
					{
						"name":"106874562 negative elongation factor B\tK15180 COBRA1; negative elongation factor B"
					},
					{
						"name":"106883768 negative elongation factor D isoform X1\tK15181 TH1L; negative elongation factor C\/D"
					},
					{
						"name":"106876999 negative elongation factor E isoform X1\tK15182 RDBP; negative elongation factor E"
					}
					]
				},
				{
					"name":"Super elongation complex (SEC)",
					"children":[
					{
						"name":"106877274 RNA polymerase II elongation factor ELL2\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"106883684 protein AF-9 isoform X1\tK15187 MLLT1_3; YEATS domain-containing protein 1\/3"
					},
					{
						"name":"106879624 cyclin-T1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"106871831 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"Little elongation complex (LEC)",
					"children":[
					{
						"name":"106877274 RNA polymerase II elongation factor ELL2\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"106879172 little elongation complex subunit 2\tK26144 ICE2; little elongation complex subunit 2"
					}
					]
				},
				{
					"name":"Brd4\/P-TEFb complex",
					"children":[
					{
						"name":"106879624 cyclin-T1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"106871831 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"BUR kinase complex"
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"7SK RNP complex",
					"children":[
					{
						"name":"106873552 protein HEXIM1\tK15189 HEXIM1_2; protein HEXIM1\/2"
					},
					{
						"name":"106878721 7SK snRNA methylphosphate capping enzyme\tK15190 MEPCE; 7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-]"
					},
					{
						"name":"106878474 la-related protein 7\tK15191 LARP7; La-related protein 7"
					},
					{
						"name":"106879624 cyclin-T1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"106871831 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"DBIRD complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"106870984 TATA-binding protein-associated factor 172\tK15192 BTAF1; TATA-binding protein-associated factor [EC:5.6.2.-]"
					},
					{
						"name":"106870325 protein Dr1\tK21751 DR1; down-regulator of transcription 1"
					},
					{
						"name":"106872669 dr1-associated corepressor\tK21752 DRAP1; Dr1-associated corepressor"
					},
					{
						"name":"106882471 protein SPT2 homolog\tK15193 SPTY2D1; protein SPT2"
					},
					{
						"name":"106880648 RNA polymerase II subunit A C-terminal domain phosphatase\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"106877370 CTD small phosphatase-like protein isoform X1\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"106878624 protein IWS1 homolog isoform X1\tK17498 SPN1; transcription factor SPN1"
					},
					{
						"name":"106871219 cysteine\/serine-rich nuclear protein 3\tK17494 CSRNP; cysteine\/serine-rich nuclear protein"
					},
					{
						"name":"106869144 RNA polymerase II-associated protein 1\tK20826 RPAP1; RNA polymerase II-associated protein 1"
					},
					{
						"name":"106879313 putative RNA polymerase II subunit B1 CTD phosphatase rpap2 isoform X1\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
					},
					{
						"name":"106869209 RNA polymerase II-associated protein 3\tK23002 RPAP3; RNA polymerase II-associated protein 3"
					},
					{
						"name":"106871018 cyclin-K\tK23326 CCNK; cyclin K"
					},
					{
						"name":"106880599 GPN-loop GTPase 2\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"106884178 GPN-loop GTPase 3\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"106877027 probable RNA polymerase II nuclear localization protein SLC7A6OS\tK28237 SLC7A6OS; RNA polymerase II nuclear localization protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase III system",
			"children":[
			{
				"name":"RNA polymerase III",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"106870739 DNA-directed RNA polymerase III subunit RPC1 isoform X1\tK03018 RPC1; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]"
					},
					{
						"name":"106873287 DNA-directed RNA polymerase III subunit RPC2\tK03021 RPC2; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]"
					},
					{
						"name":"106880528 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"106880344 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol III specific subunits",
					"children":[
					{
						"name":"106884311 DNA-directed RNA polymerase III subunit RPC3 isoform X1\tK03023 RPC3; DNA-directed RNA polymerase III subunit RPC3"
					},
					{
						"name":"106869104 DNA-directed RNA polymerase III subunit RPC4 isoform X1\tK03026 RPC4; DNA-directed RNA polymerase III subunit RPC4"
					},
					{
						"name":"106874179 DNA-directed RNA polymerase III subunit RPC5 isoform X1\tK14721 RPC5; DNA-directed RNA polymerase III subunit RPC5"
					},
					{
						"name":"106883206 DNA-directed RNA polymerase III subunit RPC6\tK03025 RPC6; DNA-directed RNA polymerase III subunit RPC6"
					},
					{
						"name":"106883453 DNA-directed RNA polymerase III subunit RPC7-like isoform X1\tK03024 RPC7; DNA-directed RNA polymerase III subunit RPC7"
					},
					{
						"name":"106872841 DNA-directed RNA polymerase III subunit RPC8\tK03022 RPC8; DNA-directed RNA polymerase III subunit RPC8"
					},
					{
						"name":"106875437 DNA-directed RNA polymerase III subunit RPC9\tK25304 RPC9; DNA-directed RNA polymerase III subunit RPC9"
					},
					{
						"name":"106871871 DNA-directed RNA polymerase III subunit RPC10 isoform X1\tK03019 RPC11; DNA-directed RNA polymerase III subunit RPC11"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"106874998 DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"106875893 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"106867543 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIIA",
					"children":[
					{
						"name":"106867056 gastrula zinc finger protein XlCGF71.1\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106867096 zinc finger protein 681\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106867150 zinc finger protein 479\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106867214 zinc finger protein 492\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106867549 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106867979 zinc finger protein 708\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106868500 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106868501 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106868508 zinc finger protein 678\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106868518 zinc finger protein 271\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106868522 zinc finger protein 271\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106868637 zinc finger protein 883\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106869801 zinc finger protein 100\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106870870 zinc finger protein 271\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106870914 gastrula zinc finger protein XlCGF7.1\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106871128 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106871469 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106871792 zinc finger protein 479\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106871970 zinc finger protein 239-like\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106871972 zinc finger protein 135\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106872369 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106872806 zinc finger protein 91\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106872819 zinc finger protein 723\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106873065 zinc finger protein 271\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106873323 zinc finger protein 850\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106873430 zinc finger protein 253\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106875583 zinc finger protein 665\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106876637 zinc finger protein 665\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106876937 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106876940 zinc finger protein 492\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106877323 zinc finger protein 665\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106877809 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106878036 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106878337 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106878559 zinc finger protein 271\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106878563 zinc finger protein 583\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106878798 zinc finger protein 850\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106879015 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106879120 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106879454 oocyte zinc finger protein XlCOF19\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106879695 zinc finger protein 681\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106879970 zinc finger protein 708\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106880337 zinc finger protein 271\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106880349 gastrula zinc finger protein XlCGF71.1\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106881294 zinc finger protein OZF\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106881298 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106881353 zinc finger protein 678\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106881464 zinc finger protein 271\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106881545 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106881548 zinc finger protein 239 isoform X1\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106881703 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106882240 zinc finger protein 596\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106882423 zinc finger protein 3\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883060 zinc finger protein 329\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883216 zinc finger protein ZFP2\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883475 zinc finger protein 737-like\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883479 zinc finger protein 883\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883564 gastrula zinc finger protein XlCGF17.1\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883567 zinc finger protein OZF-like\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883680 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883873 zinc finger protein 845\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106883881 zinc finger protein 239\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106884012 zinc finger protein 253\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106884041 gastrula zinc finger protein XlCGF7.1\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"106884143 zinc finger protein 98\tK09191 GTF3A; general transcription factor IIIA"
					}
					]
				},
				{
					"name":"TFIIIB",
					"children":[
					{
						"name":"106870472 uncharacterized protein LOC106870472\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"106877435 transcription factor IIIB 90 kDa subunit\tK15196 BRF1; transcription factor IIIB 90 kDa subunit"
					},
					{
						"name":"106877603 transcription factor IIIB 50 kDa subunit\tK15197 BRF2; transcription factor IIIB 50 kDa subunit"
					}
					]
				},
				{
					"name":"TFIIIC",
					"children":[
					{
						"name":"106867592 general transcription factor 3C polypeptide 1\tK15199 GTF3C1; general transcription factor 3C polypeptide 1"
					},
					{
						"name":"106873968 uncharacterized protein LOC106873968\tK15200 GTF3C2; general transcription factor 3C polypeptide 2"
					},
					{
						"name":"106882667 general transcription factor 3C polypeptide 4 isoform X1\tK11310 GTF3C4; general transcription factor 3C polypeptide 4 [EC:2.3.1.48]"
					},
					{
						"name":"106879314 general transcription factor 3C polypeptide 5-like isoform X1\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					},
					{
						"name":"106868450 general transcription factor 3C polypeptide 6-like\tK15203 GTF3C6; general transcription factor 3C polypeptide 6"
					}
					]
				},
				{
					"name":"TFIIIC, fungi type",
					"children":[
					{
						"name":"106879314 general transcription factor 3C polypeptide 5-like isoform X1\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"snRNA-activating protein complex (SNAPc)",
					"children":[
					{
						"name":"106879362 snRNA-activating protein complex subunit 3\tK15210 SNAPC3; snRNA-activating protein complex subunit 3"
					},
					{
						"name":"106881052 snRNA-activating protein complex subunit 5\tK15211 SNAPC5; snRNA-activating protein complex subunit 5"
					}
					]
				},
				{
					"name":"Octamer transcription factors",
					"children":[
					{
						"name":"106879804 POU domain protein 2 isoform X2\tK09364 POU2F; POU domain transcription factor, class 2"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"106878699 zinc finger protein 76\tK20828 ZNF143_76; zinc finger protein 143\/76"
					},
					{
						"name":"106871613 repressor of RNA polymerase III transcription MAF1 homolog\tK25817 MAF1; repressor of RNA polymerase III transcription MAF1"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase I system",
			"children":[
			{
				"name":"RNA polymerase I",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"106872308 DNA-directed RNA polymerase I subunit RPA1\tK02999 RPA1; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]"
					},
					{
						"name":"106875101 DNA-directed RNA polymerase I subunit RPA2 isoform X1\tK03002 RPA2; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]"
					},
					{
						"name":"106880528 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"106880344 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol I specific subunits",
					"children":[
					{
						"name":"106872426 DNA-directed RNA polymerase I subunit RPA49\tK03005 RPA49; DNA-directed RNA polymerase I subunit RPA49"
					},
					{
						"name":"106867536 DNA-directed RNA polymerase I subunit RPA43\tK03004 RPA43; DNA-directed RNA polymerase I subunit RPA43"
					},
					{
						"name":"106881925 DNA-directed RNA polymerase I subunit RPA12\tK03000 RPA12; DNA-directed RNA polymerase I subunit RPA12"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"106874998 DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"106875893 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"106867543 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"SL1\/TIF-1B",
					"children":[
					{
						"name":"106870472 uncharacterized protein LOC106870472\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"106875190 TATA box-binding protein-associated factor RNA polymerase I subunit A\tK15212 TAF1A; TATA box-binding protein-associated factor RNA polymerase I subunit A"
					},
					{
						"name":"106872230 TATA box-binding protein-associated factor RNA polymerase I subunit B\tK15213 TAF1B; TATA box-binding protein-associated factor RNA polymerase I subunit B"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"UBF",
					"children":[
					{
						"name":"106867195 uncharacterized protein LOC106867195 isoform X2\tK09273 UBTF; upstream-binding transcription factor"
					}
					]
				},
				{
					"name":"Transcription initiation factors",
					"children":[
					{
						"name":"106882567 RNA polymerase I-specific transcription initiation factor RRN3\tK15216 RRN3; RNA polymerase I-specific transcription initiation factor RRN3"
					},
					{
						"name":"106883373 general transcription factor IIF subunit 1\tK15223 UAF30; upstream activation factor subunit UAF30"
					}
					]
				},
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"106869069 transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"106881540 transcription elongation factor SPT5 isoform X1\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"NoRC (nucleolar remodeling complex)",
					"children":[
					{
						"name":"106884192 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 isoform X2\tK11654 SMARCA5; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"Transcription termination factors"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"106881951 nucleolar and coiled-body phosphoprotein 1\tK25818 NOLC1; nucleolar and coiled-body phosphoprotein 1"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				},
				{
					"name":"Sigma factors"
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"RNA polymerase-associated proteins"
				},
				{
					"name":"Transcription elongation factors"
				},
				{
					"name":"Transcription termination factor"
				}
				]
			}
			]
		},
		{
			"name":"Archaeal type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFB",
					"children":[
					{
						"name":"106877794 transcription initiation factor IIB\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFE",
					"children":[
					{
						"name":"106883880 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					}
					]
				},
				{
					"name":"TFS"
				}
				]
			}
			]
		}
		]
	}
	]
}
