{
	"name":"oho03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"Oweho_2356 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"Oweho_2859 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Oweho_3549 Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"Oweho_2568 DnaK suppressor protein\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"Oweho_1936 transcription termination factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"Oweho_0866 transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"Oweho_1475 transcription termination\/antitermination factor NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"Oweho_0101 dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"Oweho_0956 tRNA\/rRNA cytosine-C5-methylase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"Oweho_1378 RNA methyltransferase, RsmD family\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"Oweho_0724 RNA methyltransferase, RsmE family\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Oweho_1748 16S rRNA (guanine(527)-N(7))-methyltransferase GidB\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Oweho_2831 S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"Oweho_0943 putative methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Oweho_2175 putative S-adenosylmethionine-dependent methyltransferase, YraL family\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"Oweho_1030 rRNA methylase, putative, group 3\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"Oweho_0976 putative SAM-dependent methyltransferase\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"Oweho_1382 hypothetical protein\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"Oweho_1298 putative SAM-dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Oweho_1155 putative N6-adenine-specific DNA methylase\tK25137 rlmL; 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.173]"
				},
				{
					"name":"Oweho_2723 23S rRNA m2A2503 methyltransferase\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"Oweho_0409 23S rRNA (uracil-5-)-methyltransferase RumA\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"Oweho_0975 hypothetical protein\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"Oweho_2767 pseudouridine synthase family protein\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"Oweho_1164 23S RNA-specific pseudouridylate synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Oweho_1745 pseudouridine synthase, RluA family\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"Oweho_2406 acetyltransferase, N-acetylglutamate synthase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"Oweho_0723 alpha-L-glutamate ligase, RimK family\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"Oweho_3170 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"Oweho_1067 ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"Oweho_3350 ribosomal protein L11 methylase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"Oweho_2356 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"Oweho_2998 ribonuclease, Rne\/Rng family\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"Oweho_1201 RNAse H-fold protein YqgF\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"Oweho_0685 DNA\/RNA helicase, superfamily II\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"Oweho_2859 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Oweho_2845 ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"Oweho_2840 ribosome-associated GTPase EngA\tK03977 engA; GTPase"
			},
			{
				"name":"Oweho_3549 Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"Oweho_2754 GTP-binding protein HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"Oweho_3398 Sua5\/YciO\/YrdC\/YwlC family protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"Oweho_0347 (p)ppGpp synthetase, RelA\/SpoT family\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"Oweho_2048 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"Oweho_1937 hypothetical protein\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"Oweho_2315 hypothetical protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"Oweho_1566 iojap-like ribosome-associated protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"Oweho_2342 metalloprotein, YbeY\/UPF0054 family\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"Oweho_0602 ribosomal subunit interface protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"Oweho_1483 ribosomal subunit interface protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"Oweho_3363 GTP-binding protein YchF\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"Oweho_2194 putative metal-binding protein, possibly nucleic-acid binding protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}