{
	"name":"otu01001",
	"children":[
	{
		"name":"Serine\/threonine kinases: AGC group",
		"children":[
		{
			"name":"PKA family",
			"children":[
			{
				"name":"111421356 cAMP-dependent protein kinase catalytic subunit 1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
			},
			{
				"name":"111428422 cAMP-dependent protein kinase catalytic subunit alpha-like\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
			},
			{
				"name":"111429006 cAMP-dependent protein kinase catalytic subunit alpha-like\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
			},
			{
				"name":"111426589 cAMP-dependent protein kinase catalytic subunit 3\tK19584 PRKX; protein kinase X [EC:2.7.11.11]"
			}
			]
		},
		{
			"name":"PKG family",
			"children":[
			{
				"name":"111424894 cGMP-dependent protein kinase, isozyme 1-like isoform X1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"111426555 cGMP-dependent protein kinase, isozyme 2 forms cD5\/T2 isoform X1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"111427377 cGMP-dependent protein kinase, isozyme 1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"111427906 cGMP-dependent protein kinase, isozyme 1-like\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			}
			]
		},
		{
			"name":"PKC family [OT]",
			"children":[
			{
				"name":"111427268 protein kinase C, brain isozyme isoform X1\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
			},
			{
				"name":"111427436 uncharacterized protein isoform X1\tK06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]"
			},
			{
				"name":"111418808 protein kinase C isoform X1\tK18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]"
			},
			{
				"name":"111426556 atypical protein kinase C isoform X1\tK06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PKN family",
			"children":[
			{
				"name":"111426272 serine\/threonine-protein kinase N isoform X1\tK23691 PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"AUR family [OT]",
			"children":[
			{
				"name":"111426745 aurora kinase C-like\tK11481 AURKA; aurora kinase A [EC:2.7.11.1]"
			},
			{
				"name":"111414316 aurora kinase C-like\tK11479 AURKB; aurora kinase B [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PDK1 family",
			"children":[
			{
				"name":"111414770 3-phosphoinositide-dependent protein kinase 1\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"AKT\/PKB family",
			"children":[
			{
				"name":"111417663 RAC serine\/threonine-protein kinase-like\tK04456 AKT; RAC serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"111420243 RAC serine\/threonine-protein kinase\tK04456 AKT; RAC serine\/threonine-protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"SGK family [OT]"
		},
		{
			"name":"RSK family [OT]",
			"children":[
			{
				"name":"111428595 ribosomal protein S6 kinase 2 beta isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
			},
			{
				"name":"111425737 ribosomal protein S6 kinase alpha-5-like isoform X1\tK04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]"
			},
			{
				"name":"111415769 ribosomal protein S6 kinase beta-1\tK04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]"
			},
			{
				"name":"111418817 ribosomal protein S6 kinase-like 1 isoform X1\tK20839 RSKL; ribosomal protein S6 kinase-like"
			}
			]
		},
		{
			"name":"NDR family",
			"children":[
			{
				"name":"111428634 serine\/threonine-protein kinase tricornered isoform X1\tK08790 STK38; serine\/threonine kinase 38 [EC:2.7.11.1]"
			},
			{
				"name":"111429561 serine\/threonine-protein kinase Warts\tK08791 LATS1_2; serine\/threonine-protein kinase LATS1\/2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAST family [OT]",
			"children":[
			{
				"name":"111425398 microtubule-associated serine\/threonine-protein kinase 3 isoform X1\tK08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]"
			},
			{
				"name":"111413394 serine\/threonine-protein kinase greatwall\tK16309 MASTL; serine\/threonine-protein kinase greatwall [EC:2.7.11.36]"
			}
			]
		},
		{
			"name":"YANK family"
		},
		{
			"name":"DMPK family [OT]",
			"children":[
			{
				"name":"111422482 rho-associated protein kinase 1\tK04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]"
			},
			{
				"name":"111417236 serine\/threonine-protein kinase Genghis Khan isoform X1\tK16307 CDC42BP; serine\/threonine-protein kinase MRCK [EC:2.7.11.1]"
			},
			{
				"name":"111424988 citron Rho-interacting kinase\tK16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]"
			}
			]
		},
		{
			"name":"GRK family [OT]",
			"children":[
			{
				"name":"111417188 G protein-coupled receptor kinase 1\tK00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]"
			},
			{
				"name":"111427048 G protein-coupled receptor kinase 2\tK08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"111426356 serine\/threonine-protein kinase S6KL\tK17529 SGK494; uncharacterized serine\/threonine-protein kinase SgK494 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CAMK group",
		"children":[
		{
			"name":"CAMK1 family [OT]",
			"children":[
			{
				"name":"111425218 calcium\/calmodulin-dependent protein kinase type 1\tK08794 CAMK1; calcium\/calmodulin-dependent protein kinase I [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CAMK2 family",
			"children":[
			{
				"name":"111423765 calcium\/calmodulin-dependent protein kinase type II alpha chain isoform X1\tK04515 CAMK2; calcium\/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CAMKL family",
			"children":[
			{
				"name":"111416256 serine\/threonine-protein kinase BRSK2 isoform X1\tK08796 BRSK; BR serine\/threonine kinase [EC:2.7.11.1]"
			},
			{
				"name":"111417279 serine\/threonine-protein kinase grp-like\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
			},
			{
				"name":"111417052 serine\/threonine-protein kinase MARK2 isoform X1\tK08798 MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]"
			},
			{
				"name":"111419635 serine\/threonine-protein kinase MARK2-like isoform X1\tK08798 MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]"
			},
			{
				"name":"111421874 maternal embryonic leucine zipper kinase-like\tK08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]"
			},
			{
				"name":"111419862 5'-AMP-activated protein kinase catalytic subunit alpha-2\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]"
			},
			{
				"name":"111427874 serine\/threonine-protein kinase SIK2 isoform X1\tK16311 SIK2; serine\/threonine-protein kinase SIK2 [EC:2.7.11.1]"
			},
			{
				"name":"111420486 SNF-related serine\/threonine-protein kinase\tK08802 SNRK; SNF related kinase [EC:2.7.11.1]"
			},
			{
				"name":"111417372 serine\/threonine-protein kinase STK11\tK07298 STK11; serine\/threonine-protein kinase 11 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DAPK family",
			"children":[
			{
				"name":"111413634 death-associated protein kinase dapk-1-like isoform X1\tK08803 DAPK; death-associated protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DCAMKL family",
			"children":[
			{
				"name":"111420620 serine\/threonine-protein kinase GL21140\tK08805 DCLK1_2; doublecortin-like kinase 1\/2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAPKAPK family [OT]",
			"children":[
			{
				"name":"111425293 MAP kinase-activated protein kinase 2\tK04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"111427086 MAP kinase-interacting serine\/threonine-protein kinase 1 isoform X1\tK04372 MKNK; MAP kinase interacting serine\/threonine kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MLCK family"
		},
		{
			"name":"PHK family",
			"children":[
			{
				"name":"111417464 phosphorylase b kinase gamma catalytic chain, skeletal muscle\/heart isoform isoform X1\tK00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]"
			}
			]
		},
		{
			"name":"PIM family [OT]"
		},
		{
			"name":"PKD family",
			"children":[
			{
				"name":"111424569 serine\/threonine-protein kinase D1 isoform X1\tK06070 PKD; protein kinase D [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PSK family"
		},
		{
			"name":"RAD53 family",
			"children":[
			{
				"name":"111426617 myosin light chain kinase A\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trio family [OT]"
		},
		{
			"name":"TSSK family",
			"children":[
			{
				"name":"111416783 testis-specific serine\/threonine-protein kinase 3-like isoform X1\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			},
			{
				"name":"111420886 testis-specific serine\/threonine-protein kinase 3\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			},
			{
				"name":"111423560 testis-specific serine\/threonine-protein kinase 3-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			},
			{
				"name":"111427403 testis-specific serine\/threonine-protein kinase 3-like isoform X1\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CDPK family"
		},
		{
			"name":"CASK family",
			"children":[
			{
				"name":"111428258 peripheral plasma membrane protein CASK isoform X1\tK06103 CASK; calcium\/calmodulin-dependent serine protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trbl family",
			"children":[
			{
				"name":"111424737 tribbles homolog 2 isoform X1\tK08814 TRIB1_2; tribbles homolog 1\/2"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"111415532 myosin light chain kinase A-like\tK08813 STK33; serine\/threonine kinase 33 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CK1 group",
		"children":[
		{
			"name":"CK1 family [OT]",
			"children":[
			{
				"name":"111427148 casein kinase I isoform X1\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"111421539 casein kinase I isoform X3\tK08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]"
			},
			{
				"name":"111426371 casein kinase I-like isoform X1\tK08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]"
			},
			{
				"name":"111426400 casein kinase I isoform X1\tK08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TTBK family"
		},
		{
			"name":"VRK family",
			"children":[
			{
				"name":"111420479 serine\/threonine-protein kinase VRK1-like\tK08816 VRK; vaccinia related kinase [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CMGC group",
		"children":[
		{
			"name":"CDK family",
			"children":[
			{
				"name":"111429215 cyclin-dependent kinase 20-like isoform X1\tK08817 CDK20; cyclin-dependent kinase 20 [EC:2.7.11.22]"
			},
			{
				"name":"111417898 serine\/threonine-protein kinase PITSLRE\tK08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]"
			},
			{
				"name":"111423809 cyclin-dependent kinase 1\tK02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"111416934 cyclin-dependent kinase 2-like\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
			},
			{
				"name":"111413066 cyclin-dependent kinase 6 isoform X1\tK02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]"
			},
			{
				"name":"111421388 cyclin-dependent kinase 5\tK02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]"
			},
			{
				"name":"111425730 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"111416065 cyclin-dependent kinase 8\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"111414777 cyclin-dependent kinase 9\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"111425726 cyclin-dependent kinase 10 isoform X2\tK02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]"
			},
			{
				"name":"111428762 cyclin-dependent kinase 12\tK08819 CDK12_13; cyclin-dependent kinase 12\/13 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"111424201 cyclin-dependent kinase 5 homolog isoform X1\tK08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"MAPK family [OT]",
			"children":[
			{
				"name":"111426930 mitogen-activated protein kinase ERK-A\tK04371 ERK; mitogen-activated protein kinase 1\/3 [EC:2.7.11.24]"
			},
			{
				"name":"111418914 extracellular signal-regulated kinase 2 isoform X2\tK19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]"
			},
			{
				"name":"111426275 stress-activated protein kinase JNK isoform X1\tK04440 JNK; mitogen-activated protein kinase 8\/9\/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]"
			},
			{
				"name":"111425152 mitogen-activated protein kinase p38b-like isoform X1\tK04441 P38; p38 MAP kinase [EC:2.7.11.24]"
			},
			{
				"name":"111426155 serine\/threonine-protein kinase NLK isoform X1\tK04468 NLK; nemo like kinase [EC:2.7.11.24]"
			}
			]
		},
		{
			"name":"GSK family [OT]",
			"children":[
			{
				"name":"111425073 glycogen synthase kinase-3 beta isoform X2\tK03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]"
			}
			]
		},
		{
			"name":"CLK family"
		},
		{
			"name":"CDKL family",
			"children":[
			{
				"name":"111415074 cyclin-dependent kinase-like 4 isoform X1\tK08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]"
			},
			{
				"name":"111426721 cyclin-dependent kinase 3-like isoform X1\tK08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"DYRK family [OT]",
			"children":[
			{
				"name":"111425035 serine\/threonine-protein kinase minibrain isoform X1\tK08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]"
			},
			{
				"name":"111422679 dual specificity tyrosine-phosphorylation-regulated kinase 4 isoform X1\tK18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]"
			},
			{
				"name":"111425400 dual specificity tyrosine-phosphorylation-regulated kinase 2\tK18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]"
			},
			{
				"name":"111415679 homeodomain-interacting protein kinase 2 isoform X1\tK08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"111419104 uncharacterized protein\tK08827 PRPF4B; serine\/threonine-protein kinase PRP4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RCK family [OT]",
			"children":[
			{
				"name":"111416337 serine\/threonine-protein kinase dyf-5-like\tK08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]"
			},
			{
				"name":"111420184 MAPK\/MAK\/MRK overlapping kinase-like isoform X1\tK08830 RAGE; renal tumor antigen [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"SRPK family [OT]",
			"children":[
			{
				"name":"111420202 SRSF protein kinase 3\tK15409 SRPK1; serine\/threonine-protein kinase SRPK1 [EC:2.7.11.1]"
			},
			{
				"name":"111414552 serine\/threonine-protein kinase SRPK-like\tK08832 SRPK3; serine\/threonine-protein kinase SRPK3 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: STE group",
		"children":[
		{
			"name":"STE7 family",
			"children":[
			{
				"name":"111419628 dual specificity mitogen-activated protein kinase kinase dSOR1\tK04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]"
			},
			{
				"name":"111426404 dual specificity mitogen-activated protein kinase kinase 6\tK04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]"
			},
			{
				"name":"111418457 dual specificity mitogen-activated protein kinase kinase 7-like\tK04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"STE20 family",
			"children":[
			{
				"name":"111423329 mitogen-activated protein kinase kinase kinase kinase 5 isoform X2\tK08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"111414057 serine\/threonine-protein kinase mig-15 isoform X1\tK08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]"
			},
			{
				"name":"111424887 neither inactivation nor afterpotential protein C\tK08834 MYO3; myosin III [EC:2.7.11.1]"
			},
			{
				"name":"111421488 serine\/threonine-protein kinase OSR1 isoform X1\tK08835 OXSR1; serine\/threonine-protein kinase OSR1\/STK39 [EC:2.7.11.1]"
			},
			{
				"name":"111428151 serine\/threonine-protein kinase PAK 3\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"111424271 serine\/threonine-protein kinase Pak isoform X1\tK05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"111427903 serine\/threonine-protein kinase PAK mbt\tK05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"111413692 STE20-related kinase adapter protein alpha\tK08271 STRADA; STE20-related kinase adapter protein alpha"
			},
			{
				"name":"111414249 serine\/threonine-protein kinase 3\tK04412 STK3; serine\/threonine kinase 3"
			},
			{
				"name":"139428848 serine\/threonine-protein kinase 4-like\tK04411 STK4; serine\/threonine kinase 4"
			},
			{
				"name":"111414693 serine\/threonine-protein kinase 26 isoform X1\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]"
			},
			{
				"name":"111415414 serine\/threonine-protein kinase Tao\tK04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"STE11 family",
			"children":[
			{
				"name":"111421241 mitogen-activated protein kinase kinase kinase 4 isoform X1\tK04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]"
			}
			]
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: TKL group",
		"children":[
		{
			"name":"IRAK family",
			"children":[
			{
				"name":"111415372 serine\/threonine-protein kinase pelle-like isoform X1\tK04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"111427400 uncharacterized protein\tK04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"LISK family [OT]"
		},
		{
			"name":"LRRK family"
		},
		{
			"name":"MLK family",
			"children":[
			{
				"name":"111426480 mitogen-activated protein kinase kinase kinase 7-like isoform X1\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]"
			},
			{
				"name":"111423689 mitogen-activated protein kinase kinase kinase 10-like isoform X1\tK17534 MLK4; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]"
			},
			{
				"name":"111427141 mitogen-activated protein kinase kinase kinase 13-B isoform X1\tK04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]"
			},
			{
				"name":"111428636 scaffold protein ILK\tK06272 ILK; integrin-linked kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RAF family [OT]",
			"children":[
			{
				"name":"111419583 raf homolog serine\/threonine-protein kinase Raf\tK04365 BRAF; B-Raf proto-oncogene serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"111422283 kinase suppressor of Ras 2 isoform X1\tK18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RIPK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: Other",
		"children":[
		{
			"name":"RGC family [OT]",
			"children":[
			{
				"name":"111420629 atrial natriuretic peptide receptor 1\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]"
			},
			{
				"name":"111425566 atrial natriuretic peptide receptor 1\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]"
			},
			{
				"name":"111414133 retinal guanylyl cyclase 2 isoform X1\tK12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]"
			}
			]
		},
		{
			"name":"BUB family",
			"children":[
			{
				"name":"111414721 mitotic checkpoint serine\/threonine-protein kinase BUB1-like\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Bud32 family",
			"children":[
			{
				"name":"111423554 EKC\/KEOPS complex subunit TP53RK\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CAMKK family"
		},
		{
			"name":"CDC7 family",
			"children":[
			{
				"name":"111428464 cell division cycle 7-related protein kinase-like isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CK2 family",
			"children":[
			{
				"name":"111425562 casein kinase II subunit alpha isoform X1\tK03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]"
			},
			{
				"name":"111426963 casein kinase II subunit alpha-like\tK03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Haspin family",
			"children":[
			{
				"name":"111413755 uncharacterized protein isoform X1\tK16315 GSG2; serine\/threonine-protein kinase haspin [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"IKK family [OT]",
			"children":[
			{
				"name":"111417278 uncharacterized protein\tK07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]"
			},
			{
				"name":"111424559 serine\/threonine-protein kinase TBK1\tK05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]"
			}
			]
		},
		{
			"name":"IRE family",
			"children":[
			{
				"name":"111417142 serine\/threonine-protein kinase\/endoribonuclease IRE1\tK08852 ERN1; serine\/threonine-protein kinase\/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]"
			}
			]
		},
		{
			"name":"MOS family"
		},
		{
			"name":"NAK family [OT]",
			"children":[
			{
				"name":"111427202 AP2-associated protein kinase 1\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"111427257 cyclin-G-associated kinase\tK08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"111420144 serine\/threonine-protein kinase 16\tK08856 STK16; serine\/threonine kinase 16 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NEK family",
			"children":[
			{
				"name":"111428518 serine\/threonine-protein kinase Nek8 isoform X2\tK20877 NEK8; serine\/threonine-protein kinase Nek8 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF1 family",
			"children":[
			{
				"name":"111413810 serine\/threonine-protein kinase meng-po-like\tK08858 SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF2 family"
		},
		{
			"name":"NKF3 family"
		},
		{
			"name":"NKF4 family"
		},
		{
			"name":"NKF5 family"
		},
		{
			"name":"NRBP family",
			"children":[
			{
				"name":"111425932 nuclear receptor-binding protein homolog\tK08875 NRBP; nuclear receptor-binding protein"
			}
			]
		},
		{
			"name":"PEK family [OT]",
			"children":[
			{
				"name":"111424685 eukaryotic translation initiation factor 2-alpha kinase 1-like\tK16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"111425231 eukaryotic translation initiation factor 2-alpha kinase-like\tK08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PLK family [OT]",
			"children":[
			{
				"name":"111427799 serine\/threonine-protein kinase polo\tK06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]"
			},
			{
				"name":"111428468 serine\/threonine-protein kinase PLK4\tK08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]"
			}
			]
		},
		{
			"name":"SCY1 family [OT]",
			"children":[
			{
				"name":"111416653 N-terminal kinase-like protein\tK08876 SCYL1; SCY1-like protein 1"
			},
			{
				"name":"111415637 SCY1-like protein 2 isoform X1\tK17541 SCYL2; SCY1-like protein 2"
			},
			{
				"name":"111422343 SCY1-like protein 2\tK17541 SCYL2; SCY1-like protein 2"
			},
			{
				"name":"111420452 protein-associating with the carboxyl-terminal domain of ezrin\tK17542 SCYL3; SCY1-like protein 3"
			}
			]
		},
		{
			"name":"Slob family",
			"children":[
			{
				"name":"111418835 PX domain-containing protein kinase-like protein\tK17543 PXK; PX domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TBCK family",
			"children":[
			{
				"name":"111425969 TBC domain-containing protein kinase-like protein\tK17544 TBCK; TBC domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TLK family",
			"children":[
			{
				"name":"111427342 serine\/threonine-protein kinase tousled-like 2 isoform X1\tK08864 TLK; tousled-like kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TOPK family",
			"children":[
			{
				"name":"111425871 lymphokine-activated killer T-cell-originated protein kinase homolog\tK08865 PBK; PDZ-binding kinase [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"TTK family",
			"children":[
			{
				"name":"111425972 dual specificity protein kinase TTK\tK08866 TTK; serine\/threonine-protein kinase TTK\/MPS1 [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"ULK family [OT]",
			"children":[
			{
				"name":"111415190 serine\/threonine-protein kinase fused\tK06228 FU; fused [EC:2.7.11.1]"
			},
			{
				"name":"111426344 serine\/threonine-protein kinase unc-51\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
			},
			{
				"name":"111414268 serine\/threonine-protein kinase ULK3\tK21358 ULK3; serine\/threonine-protein kinase ULK3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"VPS15 family",
			"children":[
			{
				"name":"111423996 phosphoinositide 3-kinase regulatory subunit 4 isoform X1\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"WEE family",
			"children":[
			{
				"name":"111425434 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3\tK06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]"
			},
			{
				"name":"111418078 wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Wnk family"
		},
		{
			"name":"ABC1 family",
			"children":[
			{
				"name":"111414427 atypical kinase COQ8B, mitochondrial isoform X1\tK08869 ADCK; aarF domain-containing kinase"
			},
			{
				"name":"111416347 uncharacterized aarF domain-containing protein kinase 5\tK08869 ADCK; aarF domain-containing kinase"
			},
			{
				"name":"111422214 aarF domain-containing kinase 1-like\tK08869 ADCK; aarF domain-containing kinase"
			}
			]
		},
		{
			"name":"Alpha family [OT]"
		},
		{
			"name":"BCR family"
		},
		{
			"name":"BRD family [OT]",
			"children":[
			{
				"name":"111418236 bromodomain-containing protein 2-like isoform X1\tK08871 BRD2; bromodomain-containing protein 2"
			}
			]
		},
		{
			"name":"FAST family"
		},
		{
			"name":"G11 family"
		},
		{
			"name":"H11 family"
		},
		{
			"name":"PDHK family [OT]",
			"children":[
			{
				"name":"111418780 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial\tK00898 PDK2_3_4; pyruvate dehydrogenase kinase 2\/3\/4 [EC:2.7.11.2]"
			}
			]
		},
		{
			"name":"PIKK family [OT]",
			"children":[
			{
				"name":"111426931 serine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
			},
			{
				"name":"111419246 serine\/threonine-protein kinase mTor\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
			},
			{
				"name":"111424255 DNA-dependent protein kinase catalytic subunit-like\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
			},
			{
				"name":"111419737 serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RIO family [OT]",
			"children":[
			{
				"name":"111422391 serine\/threonine-protein kinase RIO1\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"111413811 uncharacterized protein\tK07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"111426385 serine\/threonine-protein kinase RIO3\tK08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TAF1 family",
			"children":[
			{
				"name":"111425857 transcription initiation factor TFIID subunit 1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
			}
			]
		},
		{
			"name":"TIF1 family [OT]",
			"children":[
			{
				"name":"111423688 E3 ubiquitin-protein ligase TRIM33 isoform X1\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"111425407 dual serine\/threonine and tyrosine protein kinase-like isoform X1\tK16288 DSTYK; dual serine\/threonine and tyrosine protein kinase [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"Bacterial family"
		}
		]
	},
	{
		"name":"Receptor serine\/threonine kinases (RSTK): TKL group",
		"children":[
		{
			"name":"TGFBR1 family [OT]",
			"children":[
			{
				"name":"111421795 activin receptor type-1\tK04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]"
			},
			{
				"name":"111413406 bone morphogenetic protein receptor type-1B isoform X1\tK13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]"
			},
			{
				"name":"111426818 TGF-beta receptor type-1 isoform X1\tK04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]"
			}
			]
		},
		{
			"name":"TGFBR2 family [OT]",
			"children":[
			{
				"name":"111416609 activin receptor type-2A\tK04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]"
			},
			{
				"name":"111428680 activin receptor type-2A\tK04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]"
			},
			{
				"name":"111419510 growth\/differentiation factor 8\tK04669 TGFBRX; TGF-beta receptor, other"
			}
			]
		}
		]
	},
	{
		"name":"Receptor tyrosine kinases (RTK)",
		"children":[
		{
			"name":"EGFR family [OT]",
			"children":[
			{
				"name":"111421879 epidermal growth factor receptor isoform X1\tK04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"INSR family [OT]",
			"children":[
			{
				"name":"111413984 uncharacterized protein\tK04527 INSR; insulin receptor [EC:2.7.10.1]"
			},
			{
				"name":"111414228 insulin-like receptor isoform X1\tK04527 INSR; insulin receptor [EC:2.7.10.1]"
			},
			{
				"name":"111425015 insulin-like growth factor 1 receptor isoform X1\tK05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"PDGFR family [OT]"
		},
		{
			"name":"FGFR family [OT]",
			"children":[
			{
				"name":"111428324 tyrosine kinase receptor Cad96Ca isoform X1\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"111425220 fibroblast growth factor receptor homolog 1-like isoform X1\tK05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"VEGFR family [OT]",
			"children":[
			{
				"name":"111421295 vascular endothelial growth factor receptor 1 isoform X1\tK05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MET family"
		},
		{
			"name":"TRK family [OT]"
		},
		{
			"name":"EPH family [OT]"
		},
		{
			"name":"AXL family"
		},
		{
			"name":"ALK family",
			"children":[
			{
				"name":"111427362 tyrosine-protein kinase receptor\tK05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"TIE family"
		},
		{
			"name":"ROR family"
		},
		{
			"name":"DDR family",
			"children":[
			{
				"name":"111414883 discoidin domain-containing receptor 2-like\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"111415884 discoidin domain-containing receptor 2-like isoform X1\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"111417581 discoidin domain-containing receptor 2-like\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"111417589 discoidin domain-containing receptor 2\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"111417596 discoidin domain-containing receptor 2-like\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RET family",
			"children":[
			{
				"name":"111421624 proto-oncogene tyrosine-protein kinase receptor Ret isoform X1\tK05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]"
			},
			{
				"name":"111425271 tyrosine-protein kinase receptor torso\tK05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"ROS family",
			"children":[
			{
				"name":"111413332 proto-oncogene tyrosine-protein kinase ROS isoform X1\tK05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"CCK family",
			"children":[
			{
				"name":"111425919 tyrosine-protein kinase-like otk\tK05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RYK family",
			"children":[
			{
				"name":"111425640 tyrosine-protein kinase Dnt-like\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			},
			{
				"name":"111425641 tyrosine-protein kinase Dnt isoform X1\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MUSK family",
			"children":[
			{
				"name":"111414207 tyrosine-protein kinase transmembrane receptor Ror2\tK05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]"
			},
			{
				"name":"111414593 tyrosine-protein kinase transmembrane receptor Ror-like\tK05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"LMR family [OT]",
			"children":[
			{
				"name":"111423476 uncharacterized protein isoform X1\tK08899 LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]"
			}
			]
		}
		]
	},
	{
		"name":"Non-receptor tyrosine kinases",
		"children":[
		{
			"name":"ABL family",
			"children":[
			{
				"name":"111420283 tyrosine-protein kinase Abl isoform X1\tK06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"ACK family",
			"children":[
			{
				"name":"111425880 activated Cdc42 kinase Ack\tK08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]"
			}
			]
		},
		{
			"name":"CSK family",
			"children":[
			{
				"name":"111414180 tyrosine-protein kinase CSK-like\tK05728 CSK; C-terminal Src kinase [EC:2.7.10.4]"
			},
			{
				"name":"111425518 tyrosine-protein kinase csk-1-like\tK05728 CSK; C-terminal Src kinase [EC:2.7.10.4]"
			}
			]
		},
		{
			"name":"FAK family",
			"children":[
			{
				"name":"111424643 focal adhesion kinase 1 isoform X2\tK05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"FES family",
			"children":[
			{
				"name":"111428350 tyrosine-protein kinase Fer isoform X2\tK08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"JAK family [OT]",
			"children":[
			{
				"name":"111424494 tyrosine-protein kinase hopscotch\tK04447 JAK2; Janus kinase 2 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SRC family",
			"children":[
			{
				"name":"111418908 tyrosine protein-kinase src-2 isoform X1\tK08892 FRK; fyn-related kinase [EC:2.7.10.2]"
			},
			{
				"name":"111414186 tyrosine-protein kinase Src64B\tK05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"TEC family",
			"children":[
			{
				"name":"111425002 tyrosine-protein kinase Btk isoform X1\tK07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SYK family",
			"children":[
			{
				"name":"111414200 tyrosine-protein kinase Shark\tK17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial"
		}
		]
	},
	{
		"name":"Histidine kinases",
		"children":[
		{
			"name":"OmpR family"
		},
		{
			"name":"NarL family"
		},
		{
			"name":"Spo family [OT]"
		},
		{
			"name":"CitB family [OT]"
		},
		{
			"name":"LytTR family [OT]"
		},
		{
			"name":"NtrC family"
		},
		{
			"name":"CheA family [OT]"
		},
		{
			"name":"Cell cycle family [OT]"
		},
		{
			"name":"Lux family [OT]"
		},
		{
			"name":"LuxR family [OT]"
		},
		{
			"name":"Other"
		}
		]
	}
	]
}