{
	"name":"ova03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"OBV_01900 putative methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"OBV_08830 putative methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"OBV_30040 cytosine-specific methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"OBV_41630 hypothetical protein\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"OBV_41880 putative methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"OBV_41890 putative methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"OBV_42640 hypothetical protein\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"OBV_43050 cytosine-specific methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"OBV_01140 putative LysR family transcriptional regulator\tK21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"OBV_07750 spoIIID; stage III sporulation protein D\tK06283 spoIIID; putative DeoR family transcriptional regulator, stage III sporulation protein D"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"OBV_11620 rbsR; ribose operon repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"OBV_11860 putative LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"OBV_37290 putative LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"OBV_11600 kdgR; transcriptional regulator KdgR\tK02525 kdgR; LacI family transcriptional regulator, kdg operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"OBV_06560 putative GntR family transcriptional regulator\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"OBV_02890 putative GntR family transcriptional regulator\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"OBV_44570 putative GntR family transcriptional regulator\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"OBV_46070 putative GntR family transcriptional regulator\tK07979 ytrA; GntR family transcriptional regulator"
				}
				]
			},
			{
				"name":"TetR\/AcrR family"
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"OBV_11770 AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"OBV_26510 AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				}
				]
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"OBV_03970 putative MarR family transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family"
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"OBV_01010 putative Fur family transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"OBV_08620 putative Fur family transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"OBV_14630 putative Fur family transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"OBV_40460 putative Fur family transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				}
				]
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"OBV_01040 putative IclR family transcriptional regulator\tK13641 iclR; IclR family transcriptional regulator, acetate operon repressor"
				},
				{
					"name":"OBV_01470 putative IclR family transcriptional regulator\tK19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor"
				},
				{
					"name":"OBV_03730 putative IclR family transcriptional regulator\tK19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor"
				}
				]
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"OBV_01220 putative transcriptional regulator\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"OBV_08900 hypothetical protein\tK21563 dnr; CRP\/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator"
				}
				]
			},
			{
				"name":"Rrf2 family"
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"OBV_07030 arsR; putative transcriptional regulator ArsR\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"OBV_00300 ArsR family transcriptional regulator\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family",
				"children":[
				{
					"name":"OBV_19230 putative PadR family transcriptional regulator\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"OBV_24830 putative PadR family transcriptional regulator\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"OBV_25870 putative PadR family transcriptional regulator\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"OBV_33920 putative PadR family transcriptional regulator\tK10947 K10947; PadR family transcriptional regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"OBV_14760 putative transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_14800 DtxR family transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_14980 putative DtxR family transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_15030 putative DNA-binding protein\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_16120 putative DtxR family transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_30450 putative transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_36520 putative transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_37950 DtxR family transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"OBV_38700 DtxR family transcriptional regulator\tK11924 mntR; DtxR family transcriptional regulator, manganese transport regulator"
				},
				{
					"name":"OBV_04470 BlaI family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_05220 putative BlaI family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_05340 BlaI family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_07530 putative BlaI family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_12390 putative BlaI family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_12620 putative regulatory protein\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_32260 putative regulatory protein\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_34020 BlaI family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_35160 putative regulatory protein\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_43390 putative regulatory protein\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_44330 BlaI family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"OBV_10220 birA; transcriptional regulator\/biotin--[acetyl-CoA-carboxylase] ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"OBV_17390 putative ModE family transcriptional regulator\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"OBV_21630 rex; redox-sensing transcriptional repressor Rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"OBV_03840 putative Xre family DNA-binding protein\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"OBV_17040 hypothetical protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"OBV_35980 putative Xre family DNA-binding protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"OBV_39300 hypothetical protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"OBV_42390 putative Xre family DNA-binding protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"OBV_02850 putative Xre family DNA-binding protein\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"OBV_03890 putative Xre family DNA-binding protein\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"OBV_19210 putative Xre family DNA-binding protein\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"OBV_29850 putative Xre family DNA-binding protein\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"OBV_44720 putative Xre family DNA-binding protein\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"OBV_17310 hypothetical protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"OBV_05210 AbrB family transcriptional regulator\tK06284 abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes"
				},
				{
					"name":"OBV_37000 spoVT; transcriptional regulator spoVT\tK04769 spoVT; AbrB family transcriptional regulator, stage V sporulation protein T"
				},
				{
					"name":"OBV_14150 parB; chromosome partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"OBV_19860 hypothetical protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"OBV_30120 putative chromosome partitioning protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"OBV_46210 ParB family chromosome partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"OBV_46370 parB; chromosome partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"OBV_p-00040 parB; putative plasmid partitioning protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"OBV_23400 putative CarD family transcriptional regulator\tK07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription"
				},
				{
					"name":"OBV_23580 argR; arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"OBV_00690 hrcA; heat-inducible transcription repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"OBV_30950 putative TenA family transcriptional activator\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]"
				},
				{
					"name":"OBV_45580 ctsR; transcriptional regulator CtsR\tK03708 ctsR; transcriptional regulator of stress and heat shock response"
				},
				{
					"name":"OBV_19180 nrdR; transcriptional regulator NrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"OBV_14040 mraZ; MraZ protein\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}
