{
	"name":"paef02022",
	"children":[
	{
		"name":"OmpR family",
		"children":[
		{
			"name":"PhoR-PhoB (phosphate starvation response)",
			"children":[
			{
				"name":"R50345_09680 histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"R50345_28970 membrane protein\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"R50345_09685 chemotaxis protein CheY\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
			},
			{
				"name":"R50345_13450 response regulator\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
			},
			{
				"name":"R50345_23860 XRE family transcriptional regulator\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
			}
			]
		},
		{
			"name":"SenX3-RegX3 (phosphate starvation response)",
			"children":[
			{
				"name":"R50345_20105 transcriptional regulator\tK07776 regX3; two-component system, OmpR family, response regulator RegX3"
			}
			]
		},
		{
			"name":"PhoQ-PhoP (magnesium transport)"
		},
		{
			"name":"EnvZ-OmpR (osmotic stress response)"
		},
		{
			"name":"RstB-RstA"
		},
		{
			"name":"CpxA-CpxR (envelope stress response)",
			"children":[
			{
				"name":"R50345_20210 histidine kinase\tK07662 cpxR; two-component system, OmpR family, response regulator CpxR"
			}
			]
		},
		{
			"name":"CssS-CssR (secretion stress response)",
			"children":[
			{
				"name":"R50345_01185 transcriptional regulator\tK07770 cssR; two-component system, OmpR family, response regulator CssR"
			}
			]
		},
		{
			"name":"CreC-CreB (phosphate regulation)"
		},
		{
			"name":"BaeS-BaeR (envelope stress response)"
		},
		{
			"name":"BasS-BasR (antimicrobial peptide resistance)"
		},
		{
			"name":"CusS-CusR (copper tolerance)"
		},
		{
			"name":"QseC-QseB (quorum sensing)"
		},
		{
			"name":"KdpD-KdpE (potassium transport)",
			"children":[
			{
				"name":"R50345_02640 histidine kinase\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
			},
			{
				"name":"R50345_13320 hypothetical protein\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"TorS-TorR (TMAO respiration)"
		},
		{
			"name":"ArcB-ArcA (anoxic redox control)"
		},
		{
			"name":"TctE-TctD (tricarboxylic acid transport)"
		},
		{
			"name":"ResE-ResD (aerobic and anaerobic respiration)",
			"children":[
			{
				"name":"R50345_20970 histidine kinase\tK07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]"
			},
			{
				"name":"R50345_14390 transcriptional regulator\tK07775 resD; two-component system, OmpR family, response regulator ResD"
			},
			{
				"name":"R50345_20975 transcriptional regulator\tK07775 resD; two-component system, OmpR family, response regulator ResD"
			}
			]
		},
		{
			"name":"VicK-VicR (cell wall metabolism)",
			"children":[
			{
				"name":"R50345_30635 histidine kinase\tK07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]"
			},
			{
				"name":"R50345_09080 PhoP family transcriptional regulator\tK07668 vicR; two-component system, OmpR family, response regulator VicR"
			},
			{
				"name":"R50345_30640 PhoP family transcriptional regulator\tK07668 vicR; two-component system, OmpR family, response regulator VicR"
			}
			]
		},
		{
			"name":"MprB-MprA (maintenance of persistent infection)",
			"children":[
			{
				"name":"R50345_08600 transcriptional regulator\tK07669 mprA; two-component system, OmpR family, response regulator MprA"
			}
			]
		},
		{
			"name":"MtrB-MtrA (osmotic stress response)"
		},
		{
			"name":"PrrB-PrrA (intracellular multiplication)"
		},
		{
			"name":"TrcS-TrcR"
		},
		{
			"name":"NrsS-NrsR (nickel tolerance)"
		},
		{
			"name":"ManS-ManR (manganese homeostasis)"
		},
		{
			"name":"NblS-NblR (photosynthesis)"
		},
		{
			"name":"SasA-RpaAB (circadian timing mediating)"
		},
		{
			"name":"SaeS-SaeR (staphylococcal virulence regulation)"
		},
		{
			"name":"BceS-BceR (bacitracin transport)",
			"children":[
			{
				"name":"R50345_01955 histidine kinase\tK11629 bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]"
			},
			{
				"name":"R50345_01960 PhoB family transcriptional regulator\tK11630 bceR; two-component system, OmpR family, bacitracin resistance response regulator BceR"
			}
			]
		},
		{
			"name":"BraS-BraR (bacitracin transport)"
		},
		{
			"name":"GraS-GraR (cationic antimicrobial peptide transport)"
		},
		{
			"name":"YxdK-YxdJ (antimicrobial peptide response)",
			"children":[
			{
				"name":"R50345_21950 membrane protein\tK11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]"
			},
			{
				"name":"R50345_21955 PhoB family transcriptional regulator\tK11634 yxdJ; two-component system, OmpR family, response regulator YxdJ"
			}
			]
		},
		{
			"name":"ChvG-ChvI (acidity sensing)"
		},
		{
			"name":"CiaH-CiaR"
		},
		{
			"name":"ParS-ParR (polymyxin-adaptive resistance)"
		},
		{
			"name":"AdeS-AdeR"
		},
		{
			"name":"VanS-VanR (VanB type vancomycin resistance)",
			"children":[
			{
				"name":"R50345_09330 histidine kinase\tK18345 vanSB; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"VanS-VanR (VanE type vancomycin resistance)",
			"children":[
			{
				"name":"R50345_21070 DeoR faimly transcriptional regulator\tK18349 vanRC; two-component system, OmpR family, response regulator VanR"
			}
			]
		},
		{
			"name":"VanS-VanR (actinomycete type vancomycin resistance)"
		},
		{
			"name":"ArlS-ArlR (virulence regulation)"
		},
		{
			"name":"Ihk-Irr (virulence regulation)"
		},
		{
			"name":"PfeS-PfeR (enterobactin-dependent iron acquisition)"
		},
		{
			"name":"NisK-NisR (lantibiotic biosynthesis)"
		},
		{
			"name":"Unclassified",
			"children":[
			{
				"name":"R50345_02810 membrane protein\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"R50345_08605 histidine kinase\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"R50345_14885 hypothetical protein\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"R50345_29415 histidine kinase\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"R50345_02815 transcriptional regulator\tK02483 K02483; two-component system, OmpR family, response regulator"
			},
			{
				"name":"R50345_27045 heme response regulator HssR\tK02483 K02483; two-component system, OmpR family, response regulator"
			}
			]
		}
		]
	},
	{
		"name":"NarL family",
		"children":[
		{
			"name":"NarX-NarL (nitrate respiration)"
		},
		{
			"name":"NarQ-NarP (nitrate respiration)",
			"children":[
			{
				"name":"R50345_11855 histidine kinase\tK07674 narQ; two-component system, NarL family, nitrate\/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"UhpB-UhpA (hexose phosphates uptake)"
		},
		{
			"name":"FusK-FusR (virulence regulation)"
		},
		{
			"name":"RcsC-RcsD-RcsB (capsule synthesis)"
		},
		{
			"name":"BarA-UvrY (central carbon metabolism)"
		},
		{
			"name":"ComP-ComA (competence)",
			"children":[
			{
				"name":"R50345_27075 hypothetical protein\tK07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]"
			},
			{
				"name":"R50345_21265 LuxR family transcriptional regulator\tK07691 comA; two-component system, NarL family, competent response regulator ComA"
			},
			{
				"name":"R50345_27070 LuxR family transcriptional regulator\tK07691 comA; two-component system, NarL family, competent response regulator ComA"
			}
			]
		},
		{
			"name":"EvgS-EvgA (acid and drug tolerance)"
		},
		{
			"name":"DegS-DegU (multicellular behavior control)",
			"children":[
			{
				"name":"R50345_28645 histidine kinase\tK07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]"
			},
			{
				"name":"R50345_28640 chemotaxis protein CheY\tK07692 degU; two-component system, NarL family, response regulator DegU"
			}
			]
		},
		{
			"name":"DesK-DesR (membrane lipid fluidity regulation)",
			"children":[
			{
				"name":"R50345_01860 histidine kinase\tK07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]"
			},
			{
				"name":"R50345_12905 histidine kinase\tK07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]"
			},
			{
				"name":"R50345_01865 hypothetical protein\tK07693 desR; two-component system, NarL family, response regulator DesR"
			},
			{
				"name":"R50345_12910 transcriptional regulatory protein DesR\tK07693 desR; two-component system, NarL family, response regulator DesR"
			}
			]
		},
		{
			"name":"VraS-VraR (cell-wall peptidoglycan synthesis)"
		},
		{
			"name":"LiaS-LiaR (cell wall stress response)",
			"children":[
			{
				"name":"R50345_04515 histidine kinase\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
			},
			{
				"name":"R50345_08580 histidine kinase\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
			},
			{
				"name":"R50345_26265 histidine kinase\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
			},
			{
				"name":"R50345_08585 LuxR family transcriptional regulator\tK11618 liaR; two-component system, NarL family, response regulator LiaR"
			},
			{
				"name":"R50345_26260 LuxR family transcriptional regulator\tK11618 liaR; two-component system, NarL family, response regulator LiaR"
			}
			]
		},
		{
			"name":"DevS-DevR (redox response)"
		},
		{
			"name":"NreB-NreC (dissimilatory nitrate\/nitrite reduction)"
		},
		{
			"name":"YdfH-YdfI"
		},
		{
			"name":"SalK-SalR"
		},
		{
			"name":"PprA–PprB (biofilm formation)"
		},
		{
			"name":"Unclassified"
		}
		]
	},
	{
		"name":"Spo family",
		"children":[
		{
			"name":"KinABCDE-Spo0FA (sporulation control)",
			"children":[
			{
				"name":"R50345_04480 hypothetical protein\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"R50345_04485 histidine kinase\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"R50345_11785 sporulation kinase\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"R50345_15075 histidine kinase\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"R50345_19680 hypothetical protein\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"R50345_00625 CheY-like receiver\tK02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F"
			},
			{
				"name":"R50345_21495 chemotaxis protein CheY\tK07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A"
			}
			]
		}
		]
	},
	{
		"name":"CitB family",
		"children":[
		{
			"name":"CitA-CitB (citrate fermentation)"
		},
		{
			"name":"CitS-CitT (magnesium-citrate transport)"
		},
		{
			"name":"DcuS-DcuR (C4-dicarboxylate metabolism)"
		},
		{
			"name":"DctS-DctR (C4-dicarboxylate transport)"
		},
		{
			"name":"MalK-MalR (malate transport)"
		},
		{
			"name":"Unclassified"
		}
		]
	},
	{
		"name":"LytTR family",
		"children":[
		{
			"name":"LysS-LysR"
		},
		{
			"name":"AlgZ-AlgR (alginate production)"
		},
		{
			"name":"NatK-NatR (sodium extrusion)"
		},
		{
			"name":"AgrC-AgrA (exoprotein synthesis)"
		},
		{
			"name":"AgrC2-AgrA2 (virulence regulation)"
		},
		{
			"name":"ComD-ComE (competence)"
		},
		{
			"name":"BtsS-BtsR (pyruvate reutilization)"
		},
		{
			"name":"PyrS-PyrR (pyruvate reutilization)",
			"children":[
			{
				"name":"R50345_01755 membrane protein\tK27884 pyrS; two-component system, LytTR family, high-concentration pyruvate sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"R50345_01760 LytTR family transcriptional regulator\tK27885 pyrR; two-component system, LytTR family, high-concentration pyruvate response regulator"
			}
			]
		},
		{
			"name":"Unclassified"
		}
		]
	},
	{
		"name":"NtrC family",
		"children":[
		{
			"name":"GlnL-GlnG (nitrogen regulation)"
		},
		{
			"name":"NtrY-NtrX (nitrogen regulation)"
		},
		{
			"name":"HydH-HydG (metal tolerance)"
		},
		{
			"name":"AtoS-AtoC (cPHB biosynthesis)"
		},
		{
			"name":"PilS-PilR (type 4 fimbriae synthesis)"
		},
		{
			"name":"GlrK-GlrR (amino sugar metabolism)"
		},
		{
			"name":"PgtB-PgtA (phosphoglycerate transport)"
		},
		{
			"name":"DctB-DctD (C4-dicarboxylate transport)"
		},
		{
			"name":"KinB-AlgB (alginate production)"
		},
		{
			"name":"HupT-HupR (hydrogenase synthesis regulation)"
		},
		{
			"name":"Unclassified"
		}
		]
	},
	{
		"name":"CheA family",
		"children":[
		{
			"name":"CheA-CheYBV (chemotaxis)",
			"children":[
			{
				"name":"R50345_18735 chemotaxis protein CheA\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]"
			},
			{
				"name":"R50345_29595 hypothetical protein\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]"
			},
			{
				"name":"R50345_18785 chemotaxis protein CheY\tK03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY"
			},
			{
				"name":"R50345_18740 chemotaxis protein CheY\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
			},
			{
				"name":"R50345_21255 hypothetical protein\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
			}
			]
		},
		{
			"name":"ChpA-ChpB\/PilGH (chemosensory)"
		},
		{
			"name":"PixL-PixGH (positive phototaxis)"
		},
		{
			"name":"WspE-WspRF (chemosensory)"
		},
		{
			"name":"Cph1-Rcp1 (light response)"
		}
		]
	},
	{
		"name":"Cell cycle family",
		"children":[
		{
			"name":"PleC-PleD (cell fate control)"
		},
		{
			"name":"CckA-CtrA\/CpdR (cell cycle control)"
		},
		{
			"name":"Hk1-Rrp1 (glycerol uptake and utilization)"
		}
		]
	},
	{
		"name":"Lux family",
		"children":[
		{
			"name":"LuxQN\/CqsS-LuxU-LuxO (quorum sensing)"
		}
		]
	},
	{
		"name":"LuxR family",
		"children":[
		{
			"name":"DctS-DctR (C4-dicarboxylate transport)"
		},
		{
			"name":"TtrS-TtrR (tetrathionate respiration)"
		},
		{
			"name":"FixL-FixJ (nitrogen fixation)"
		},
		{
			"name":"SsrA-SsrB"
		}
		]
	},
	{
		"name":"Other families",
		"children":[
		{
			"name":"FlrB-FlrC (polar flagellar synthesis)"
		},
		{
			"name":"AauS-AauR (acidic amino acids utilization)"
		},
		{
			"name":"SLN1-YPD1-SSK1\/SKN7 (osmosensing)"
		},
		{
			"name":"RpfC-RpfG (cell-to-cell signaling)"
		},
		{
			"name":"GlnK-GlnL (glutamine utilization)"
		},
		{
			"name":"HspS-HspR (hexose phosphates uptake)"
		},
		{
			"name":"YesM-YesN",
			"children":[
			{
				"name":"R50345_02270 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_04070 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_04180 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_06810 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_07215 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_07275 helicase Ski2\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_07470 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_07850 helicase Ski2\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_08055 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_08270 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_09755 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_09810 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_09925 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_11205 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_11310 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_11505 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_12675 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_12885 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_13135 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_14105 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_15045 membrane protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_15125 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_15770 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_16305 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_16465 peptidase C56\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_17660 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_17970 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_19245 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_20260 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_21155 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_21725 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_21760 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_21815 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_22290 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_22365 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_22410 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_22535 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_23610 helicase Ski2\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_24660 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_24750 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_24890 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_24980 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_25025 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_26095 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_26780 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_27240 histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_30045 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_30235 sensor with HAMP domain protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"R50345_02275 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_04065 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_04175 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_06815 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_07220 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_07280 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_07475 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_07855 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_08095 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_08975 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_09760 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_09820 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_09920 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_11200 two component transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_11315 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_11500 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_12680 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_12895 response regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_13140 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_14100 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_15040 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_15120 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_15775 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_16300 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_16470 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_17655 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_17975 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_19250 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_20420 transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_21150 chemotaxis protein CheY\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_21730 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_21810 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_22265 transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_22285 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_22370 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_23605 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_24655 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_24745 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_24885 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_24985 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_25020 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_26090 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_26100 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_26775 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_27235 chemotaxis protein CheY\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_30050 hypothetical protein\tK07720 yesN; two-component system, response regulator YesN"
			},
			{
				"name":"R50345_30230 AraC family transcriptional regulator\tK07720 yesN; two-component system, response regulator YesN"
			}
			]
		},
		{
			"name":"CikA"
		},
		{
			"name":"RegB-RegA (redox response)"
		},
		{
			"name":"FitF-FitH (insecticidal toxin regulation)"
		},
		{
			"name":"PhcS-PhcRQ"
		},
		{
			"name":"SagS-HptB-HsbR (swarming activity and biofilm formation)"
		},
		{
			"name":"PdtaS-PdtaR"
		},
		{
			"name":"NasS-NasT"
		},
		{
			"name":"Unclassified",
			"children":[
			{
				"name":"R50345_15205 histidine kinase\tK19694 chiS; two-component system, sensor histidine kinase ChiS"
			}
			]
		}
		]
	}
	]
}