{
	"name":"paeh03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"H70357_16335 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"H70357_26855 era; GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"H70357_27735 GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"H70357_21320 nusA; transcription elongation factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"H70357_24985 nitrogen utilization protein B\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"H70357_32085 antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"H70357_12990 RNA pseudouridine synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"H70357_00155 16S rRNA methyltransferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"H70357_15050 16S rRNA methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"H70357_32060 16S rRNA methyltransferase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"H70357_16265 DNA methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"H70357_26975 16S rRNA methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"H70357_35325 16S rRNA methyltransferase\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"H70357_26640 16S rRNA methyltransferase\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"H70357_00120 16S rRNA methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"H70357_20430 SAM-dependent methyltransferase\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]"
				},
				{
					"name":"H70357_24955 RNA methyltransferase\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"H70357_32105 RNA methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"H70357_35060 50S rRNA methyltransferase\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"H70357_23190 SAM-dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"H70357_26950 SAM-dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"H70357_20200 SAM-dependent methyltransferase\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"H70357_15055 ribosomal RNA large subunit methyltransferase N\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"H70357_34010 RNA methyltransferase\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"H70357_24955 RNA methyltransferase\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"H70357_03485 RNA methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"H70357_23890 RNA pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"H70357_07105 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"H70357_09820 hypothetical protein\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"H70357_23195 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"H70357_26480 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"H70357_27890 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"H70357_00475 pseudouridine synthase\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				},
				{
					"name":"H70357_15505 pseudouridine synthase\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"H70357_00505 acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"H70357_05740 alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"H70357_13835 acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"H70357_00460 acetyltransferase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"H70357_18265 alanine acetyltransferase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"H70357_33105 alanine acetyltransferase\tK03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-]"
			},
			{
				"name":"H70357_21695 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"H70357_26985 50S ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"H70357_16335 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"H70357_27770 ribonuclease\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"H70357_09380 Holliday junction resolvase\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			},
			{
				"name":"H70357_32110 ribonuclease III\tK11145 mrnC; mini-ribonuclease III [EC:3.1.26.-]"
			},
			{
				"name":"H70357_00150 DNA primase\tK05985 rnmV; ribonuclease M5 [EC:3.1.26.8]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"H70357_12450 RNA helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"H70357_12880 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"H70357_33175 RNA helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"H70357_26855 era; GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"H70357_15070 GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"H70357_20510 GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"H70357_23735 engA; GTP-binding protein Der\tK03977 engA; GTPase"
			},
			{
				"name":"H70357_27735 GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"H70357_21645 GTPase\tK14540 rbgA; ribosome biogenesis GTPase A"
			},
			{
				"name":"H70357_01400 GTP-binding protein\tK03665 hflX; GTPase"
			},
			{
				"name":"H70357_20395 GTP-binding protein HflX\tK03665 hflX; GTPase"
			},
			{
				"name":"H70357_08910 GTPase\tK06948 yqeH; 30S ribosome assembly GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"H70357_32940 translation factor\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"H70357_27440 (p)ppGpp synthetase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"H70357_21300 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"H70357_21325 ribosome maturation factor RimP\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"H70357_00015 RNA-binding protein S4\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"H70357_08935 ribosomal silencing factor RsfS\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"H70357_26870 metalloprotease\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"H70357_08920 RNA-binding protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"H70357_32620 sigma-54 modulation protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"H70357_32970 GTP-binding protein\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"H70357_16290 metal-binding protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}