{
	"name":"paem02042",
	"children":[
	{
		"name":"Type III toxins: Intracellular toxins",
		"children":[
		{
			"name":"ADP-ribosyltransferase",
			"children":[
			{
				"name":"Diphtheria toxin (DT)"
			},
			{
				"name":"Cholera toxin\/Heat-labile enterotoxin"
			},
			{
				"name":"Exototoxin-A (ETA)",
				"children":[
				{
					"name":"U769_20020 exotoxin A\tK11020 toxA; exotoxin A [EC:2.4.2.-]"
				}
				]
			},
			{
				"name":"Exoenzyme S\/T",
				"children":[
				{
					"name":"U769_00245 ADP-ribosyltransferase\tK16636 exoT; exoenzyme T"
				}
				]
			},
			{
				"name":"Pertussis toxin (PT)"
			},
			{
				"name":"ADP-ribosyltransferase toxin ArtA\/B"
			},
			{
				"name":"ADP-ribosyltransferase SpyA"
			}
			]
		},
		{
			"name":"Metalloprotease",
			"children":[
			{
				"name":"Botulinum neurotoxin (BoNT)"
			},
			{
				"name":"Tetanus toxin (TeTx)"
			},
			{
				"name":"Anthrax lethal toxin"
			}
			]
		},
		{
			"name":"Adenylate cyclase",
			"children":[
			{
				"name":"Anthrax edema toxin"
			},
			{
				"name":"Adenylate cyclase toxin (ACT)"
			},
			{
				"name":"Exoenzyme Y",
				"children":[
				{
					"name":"U769_14370 adenylate cyclase\tK16637 K16637; adenylate cyclase ExoY"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Zona occludens toxin",
				"children":[
				{
					"name":"U769_25610 hypothetical protein\tK10954 zot; zona occludens toxin"
				}
				]
			},
			{
				"name":"Shiga toxin"
			},
			{
				"name":"Subtilase cytotoxin"
			},
			{
				"name":"Cytotoxic necrotizing factor 1\/Dermonecrotic toxin (DNT)"
			},
			{
				"name":"Enterotoxin ShET-1"
			},
			{
				"name":"Vacuolating cytotoxin"
			},
			{
				"name":"Cytolethal distending toxin"
			},
			{
				"name":"Exfoliative toxin type A"
			},
			{
				"name":"Toxin A\/B"
			},
			{
				"name":"Insecticidal toxin FitD\/Mcf"
			},
			{
				"name":"TccC-type insecticidal toxin"
			},
			{
				"name":"Heat-stable enterotoxin"
			},
			{
				"name":"Typhoid toxin"
			}
			]
		}
		]
	},
	{
		"name":"Type II toxins: Membrane damaging toxins",
		"children":[
		{
			"name":"Pore-forming toxins, Beta-pore-forming\/Cholesterol-dependent"
		},
		{
			"name":"Pore-forming toxins, RTX"
		},
		{
			"name":"Pore-forming toxins, Other",
			"children":[
			{
				"name":"U769_06135 membrane protein\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
			},
			{
				"name":"U769_29465 membrane protein\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
			},
			{
				"name":"U769_26525 hemolysin D\tK11068 hlyIII; hemolysin III"
			}
			]
		},
		{
			"name":"Toxins that enzymatically damage the membrane",
			"children":[
			{
				"name":"U769_08250 phospholipase C\tK01114 plc; phospholipase C [EC:3.1.4.3]"
			},
			{
				"name":"U769_21595 hemolytic phospholipase C\tK01114 plc; phospholipase C [EC:3.1.4.3]"
			},
			{
				"name":"U769_20885 exosortase\tK16638 exoU; exoenzyme U"
			}
			]
		}
		]
	},
	{
		"name":"Type I toxins: Toxins that act from the cell surface",
		"children":[
		{
			"name":"Superantigens"
		}
		]
	},
	{
		"name":"Toxins that damage the extracellular matrix",
		"children":[
		{
			"name":"Hyaluronidases\/Collagenases"
		}
		]
	},
	{
		"name":"Not specified",
		"children":[
		{
			"name":"Ymt"
		},
		{
			"name":"Hydrogen cyanide production",
			"children":[
			{
				"name":"U769_14365 (2Fe-2S)-binding protein\tK10814 hcnA; hydrogen cyanide synthase HcnA [EC:1.4.99.5]"
			},
			{
				"name":"U769_14360 (2Fe-2S)-binding protein\tK10815 hcnB; hydrogen cyanide synthase HcnB [EC:1.4.99.5]"
			},
			{
				"name":"U769_14355 hydrogen cyanide synthase HcnC\tK10816 hcnC; hydrogen cyanide synthase HcnC [EC:1.4.99.5]"
			}
			]
		},
		{
			"name":"Beta2 toxin"
		},
		{
			"name":"Enterotoxin"
		},
		{
			"name":"BteA"
		},
		{
			"name":"Superantigen-like protein"
		}
		]
	}
	]
}
