{
	"name":"pagc02044",
	"children":[
	{
		"name":"Type I secretion system",
		"children":[
		{
			"name":"alpha-Hemolysin\/cyclolysin transporter",
			"children":[
			{
				"name":"BEE12_03855 outer membrane channel protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"BEE12_23500 transporter\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"RTX toxin transporter",
			"children":[
			{
				"name":"BEE12_03855 outer membrane channel protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"BEE12_23500 transporter\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Multiple protein transporter",
			"children":[
			{
				"name":"BEE12_03855 outer membrane channel protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"BEE12_23500 transporter\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Adhesin protein transporter",
			"children":[
			{
				"name":"BEE12_00950 ATP-binding protein\tK12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB"
			},
			{
				"name":"BEE12_09730 ATP-binding protein\tK12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB"
			},
			{
				"name":"BEE12_00945 secretion protein HlyD\tK12542 lapC; membrane fusion protein, adhesin transport system"
			},
			{
				"name":"BEE12_09725 secretion protein HlyD\tK12542 lapC; membrane fusion protein, adhesin transport system"
			},
			{
				"name":"BEE12_00955 type I secretion system outer membrane protein\tK12543 lapE; outer membrane protein, adhesin transport system"
			},
			{
				"name":"BEE12_09735 transporter\tK12543 lapE; outer membrane protein, adhesin transport system"
			}
			]
		},
		{
			"name":"RaxAB-RaxC type I secretion system protein",
			"children":[
			{
				"name":"BEE12_23495 anibiotic ABC transporter\tK13408 cvaA; membrane fusion protein"
			},
			{
				"name":"BEE12_23490 ABC transporter\tK13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB\/MchF\/RaxB"
			},
			{
				"name":"BEE12_03855 outer membrane channel protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"BEE12_23500 transporter\tK12340 tolC; outer membrane protein"
			}
			]
		}
		]
	},
	{
		"name":"Type II secretion system",
		"children":[
		{
			"name":"General secretion pathway protein"
		},
		{
			"name":"Pilin secretion\/fimbrial assembly protein",
			"children":[
			{
				"name":"BEE12_02045 type IV pilus biogenesis\/stability protein PilW\tK02656 pilF; type IV pilus assembly protein PilF"
			},
			{
				"name":"BEE12_03385 type IV pili twitching motility protein PilT\tK02669 pilT; twitching motility protein PilT"
			}
			]
		},
		{
			"name":"Tight adherence (Tad) export apparatus"
		},
		{
			"name":"Toxin co-regulated pilus biosynthesis protein"
		},
		{
			"name":"MSHA pilus biogenesis protein"
		},
		{
			"name":"Type IVa pilus homolog protein",
			"children":[
			{
				"name":"BEE12_03055 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02679 ppdA; prepilin peptidase dependent protein A"
			},
			{
				"name":"BEE12_03050 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02680 ppdB; prepilin peptidase dependent protein B"
			},
			{
				"name":"BEE12_03040 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02681 ppdC; prepilin peptidase dependent protein C"
			},
			{
				"name":"BEE12_10415 prepilin peptidase-dependent pilin\tK02682 ppdD; prepilin peptidase dependent protein D"
			},
			{
				"name":"BEE12_10410 type II secretion system protein GspE\tK02504 hofB; protein transport protein HofB"
			},
			{
				"name":"BEE12_10405 type IV pilin biogenesis protein\tK02505 hofC; protein transport protein HofC"
			},
			{
				"name":"BEE12_05190 pilus assembly protein HofM\tK12288 hofM; pilus assembly protein HofM"
			},
			{
				"name":"BEE12_05185 fimbrial assembly protein\tK12289 hofN; pilus assembly protein HofN"
			},
			{
				"name":"BEE12_05180 hypothetical protein\tK12290 hofO; pilus assembly protein HofO"
			},
			{
				"name":"BEE12_05175 hypothetical protein\tK12291 hofP; pilus assembly protein HofP"
			},
			{
				"name":"BEE12_05170 hofQ; DNA transporter HofQ\tK02507 hofQ; protein transport protein HofQ"
			},
			{
				"name":"BEE12_03385 type IV pili twitching motility protein PilT\tK02669 pilT; twitching motility protein PilT"
			},
			{
				"name":"BEE12_03395 hypothetical protein\tK02221 yggT; YggT family protein"
			}
			]
		},
		{
			"name":"Archaeal flagellar protein"
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) core components",
			"children":[
			{
				"name":"BEE12_11600 hypothetical protein\tK02237 comEA; competence protein ComEA"
			}
			]
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) related proteins"
		}
		]
	},
	{
		"name":"Type III secretion system",
		"children":[
		{
			"name":"Type III secretion core apparatus",
			"children":[
			{
				"name":"BEE12_14920 EscC\/YscC\/HrcC family type III secretion system outer membrane ring protein\tK03219 yscC; type III secretion protein C"
			},
			{
				"name":"BEE12_14975 type III secretion protein\tK03220 yscD; type III secretion protein D"
			},
			{
				"name":"BEE12_14895 AraC family transcriptional regulator\tK04053 yscI; type III secretion protein I"
			},
			{
				"name":"BEE12_14910 serine kinase\tK03223 yscL; type III secretion protein L"
			},
			{
				"name":"BEE12_14970 EscN\/YscN\/HrcN family type III secretion system ATPase\tK03224 yscN; ATP synthase in type III secretion protein N [EC:7.4.2.8]"
			},
			{
				"name":"BEE12_14965 hypothetical protein\tK04056 yscO; type III secretion protein O"
			},
			{
				"name":"BEE12_14950 EscR\/YscR\/HrcR family type III secretion system export apparatus protein\tK03226 yscR; type III secretion protein R"
			},
			{
				"name":"BEE12_14945 EscS\/YscS\/HrcS family type III secretion system export apparatus protein\tK03227 yscS; type III secretion protein S"
			},
			{
				"name":"BEE12_14940 EscT\/YscT\/HrcT family type III secretion system export apparatus protein\tK03228 yscT; type III secretion protein T"
			},
			{
				"name":"BEE12_14935 EscU\/YscU\/HrcU family type III secretion system export apparatus switch protein\tK03229 yscU; type III secretion protein U"
			},
			{
				"name":"BEE12_14980 EscV\/YscV\/HrcV family type III secretion system export apparatus protein\tK03230 yscV; type III secretion protein V"
			},
			{
				"name":"BEE12_14985 SepL\/TyeA\/HrpJ family type III secretion system gatekeeper\tK04058 yscW; type III secretion protein W"
			}
			]
		},
		{
			"name":"Type III secretion related proteins"
		},
		{
			"name":"Flagellar export apparatus",
			"children":[
			{
				"name":"BEE12_18485 flagellar biosynthesis protein FlhA\tK02400 flhA; flagellar biosynthesis protein FlhA"
			},
			{
				"name":"BEE12_18490 flagellar biosynthesis protein FlhB\tK02401 flhB; flagellar biosynthesis protein FlhB"
			},
			{
				"name":"BEE12_18775 flagellar M-ring protein FliF\tK02409 fliF; flagellar M-ring protein FliF"
			},
			{
				"name":"BEE12_18785 flagellar assembly protein FliH\tK02411 fliH; flagellar assembly protein FliH"
			},
			{
				"name":"BEE12_18790 fliI; flagellum-specific ATP synthase FliI\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]"
			},
			{
				"name":"BEE12_18815 flagellar motor switch protein FliN\tK02417 fliN; flagellar motor switch protein FliN"
			},
			{
				"name":"BEE12_18820 flagellar biosynthetic protein FliO\tK02418 fliO; flagellar protein FliO\/FliZ"
			},
			{
				"name":"BEE12_18825 flagellar biosynthetic protein FliP\tK02419 fliP; flagellar biosynthesis protein FliP"
			},
			{
				"name":"BEE12_18830 fliQ; flagellar export apparatus protein FliQ\tK02420 fliQ; flagellar biosynthesis protein FliQ"
			},
			{
				"name":"BEE12_18835 flagellar biosynthetic protein FliR\tK02421 fliR; flagellar biosynthesis protein FliR"
			}
			]
		}
		]
	},
	{
		"name":"Type IV secretion system",
		"children":[
		{
			"name":"Conjugal DNA-protein transfer (VirB\/D) protein"
		},
		{
			"name":"DNA uptake competence system protein"
		},
		{
			"name":"Conjugal transfer pilus assembly protein",
			"children":[
			{
				"name":"BEE12_22805 type-F conjugative transfer system pilin assembly protein TraF\tK12057 traF; conjugal transfer pilus assembly protein TraF"
			},
			{
				"name":"BEE12_22810 conjugal transfer protein TraN\tK12058 traN; conjugal transfer mating pair stabilization protein TraN"
			},
			{
				"name":"BEE12_22815 type-F conjugative transfer system pilin assembly protein TrbC\tK12059 trbC; conjugal transfer pilus assembly protein TrbC"
			},
			{
				"name":"BEE12_22820 conjugal transfer protein TraU\tK12060 traU; conjugal transfer pilus assembly protein TraU"
			},
			{
				"name":"BEE12_22850 conjugal transfer protein TraW\tK12061 traW; conjugal transfer pilus assembly protein TraW"
			},
			{
				"name":"BEE12_22855 type-F conjugative transfer system protein TrbI\tK28223 trbI; conjugal transfer pilus assembly protein TrbI"
			},
			{
				"name":"BEE12_22860 type IV secretion system protein TraC\tK12063 traC; conjugal transfer ATP-binding protein TraC"
			},
			{
				"name":"BEE12_22870 type IV conjugative transfer system protein TraV\tK12064 traV; conjugal transfer pilus assembly protein TraV"
			},
			{
				"name":"BEE12_22895 conjugal transfer protein TraB\tK12065 traB; conjugal transfer pilus assembly protein TraB"
			},
			{
				"name":"BEE12_22900 conjugal transfer protein TraK\tK12066 traK; conjugal transfer pilus assembly protein TraK"
			},
			{
				"name":"BEE12_22905 conjugal transfer protein\tK12067 traE; conjugal transfer pilus assembly protein TraE"
			},
			{
				"name":"BEE12_22910 type IV conjugative transfer system protein TraL\tK12068 traL; conjugal transfer pilus assembly protein TraL"
			},
			{
				"name":"BEE12_08705 conjugative coupling factor TraD, PFGI-1 class\tK12071 traD; conjugal transfer pilus assembly protein TraD"
			},
			{
				"name":"BEE12_03165 bifunctional protein-disulfide isomerase\/oxidoreductase DsbC\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"BEE12_22775 conjugal transfer protein TraH\tK12072 traH; conjugative transfer pilus assembly protein TraH"
			}
			]
		},
		{
			"name":"Pertussis toxin exporter"
		},
		{
			"name":"Cag pathogenicity island (PAI) protein"
		},
		{
			"name":"Icm\/Dot secretion system protein"
		},
		{
			"name":"Trb secretion system protein"
		}
		]
	},
	{
		"name":"Type V secretion system",
		"children":[
		{
			"name":"Autotransporter-1 (AT-1) family",
			"children":[
			{
				"name":"BEE12_23560 hypothetical protein\tK12684 esp; serine protease autotransporter [EC:3.4.21.-]"
			},
			{
				"name":"BEE12_21180 autotransporter outer membrane beta-barrel domain-containing protein\tK12686 apeE; outer membrane lipase\/esterase"
			}
			]
		},
		{
			"name":"Autotransporter-2 (AT-2) family"
		},
		{
			"name":"Two-partner secretion (TPS) family"
		}
		]
	},
	{
		"name":"Type VI secretion system",
		"children":[
		{
			"name":"Imp\/Vas secretion system core components",
			"children":[
			{
				"name":"BEE12_14690 type VI secretion system protein ImpL\tK11891 impL; type VI secretion system protein ImpL"
			},
			{
				"name":"BEE12_15110 type VI secretion system protein ImpL\tK11891 impL; type VI secretion system protein ImpL"
			},
			{
				"name":"BEE12_14685 hypothetical protein\tK11892 impK; type VI secretion system protein ImpK"
			},
			{
				"name":"BEE12_15115 hypothetical protein\tK11892 impK; type VI secretion system protein ImpK"
			},
			{
				"name":"BEE12_14680 type VI secretion system-associated protein\tK11893 impJ; type VI secretion system protein ImpJ"
			},
			{
				"name":"BEE12_14760 hypothetical protein\tK11895 impH; type VI secretion system protein ImpH"
			},
			{
				"name":"BEE12_14755 type VI secretion system protein ImpG\tK11896 impG; type VI secretion system protein ImpG"
			},
			{
				"name":"BEE12_14750 hypothetical protein\tK11897 impF; type VI secretion system protein ImpF"
			},
			{
				"name":"BEE12_14710 EvpB family type VI secretion protein\tK11900 impC; type VI secretion system protein ImpC"
			},
			{
				"name":"BEE12_14705 type VI secretion system-associated protein\tK11901 impB; type VI secretion system protein ImpB"
			},
			{
				"name":"BEE12_14700 hypothetical protein\tK11902 impA; type VI secretion system protein ImpA"
			},
			{
				"name":"BEE12_01450 hypothetical protein\tK11903 hcp; type VI secretion system secreted protein Hcp"
			},
			{
				"name":"BEE12_14715 hypothetical protein\tK11903 hcp; type VI secretion system secreted protein Hcp"
			},
			{
				"name":"BEE12_20520 Hcp family T6SS protein CtsH1\tK11903 hcp; type VI secretion system secreted protein Hcp"
			},
			{
				"name":"BEE12_14675 type VI secretion system-associated lipoprotein\tK11906 vasD; type VI secretion system protein VasD"
			},
			{
				"name":"BEE12_14765 ClpV1 family T6SS ATPase\tK11907 vasG; type VI secretion system protein VasG"
			}
			]
		},
		{
			"name":"Imp\/Vas secretion system related proteins",
			"children":[
			{
				"name":"BEE12_14695 type VI secretion-associated protein\tK11890 impM; type VI secretion system protein ImpM"
			},
			{
				"name":"BEE12_15105 type VI secretion-associated protein\tK11890 impM; type VI secretion system protein ImpM"
			},
			{
				"name":"BEE12_14745 protein of avirulence locus ImpE\tK11898 impE; type VI secretion system protein ImpE"
			}
			]
		}
		]
	},
	{
		"name":"Type VII secretion system",
		"children":[
		{
			"name":"ESX secretion system protein"
		}
		]
	},
	{
		"name":"Chaperone-usher system",
		"children":[
		{
			"name":"Type 1 pilus assembly protein",
			"children":[
			{
				"name":"BEE12_08525 oxidoreductase\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"BEE12_08545 fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"BEE12_16695 fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"BEE12_19645 fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"BEE12_22300 fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"BEE12_23510 adhesin\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"BEE12_23525 pilus assembly protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"BEE12_03730 protein CsuC\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"BEE12_08540 pilus assembly protein PapD\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"BEE12_19650 fimbrial assembly protein\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"BEE12_22305 phytochrome sensor protein\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"BEE12_08535 pilus assembly protein PapC\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"BEE12_16705 fimbrial assembly protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"BEE12_19655 export and assembly usher protein of type 1 fimbriae\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"BEE12_21935 hypothetical protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"BEE12_22310 usher protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"BEE12_23515 hypothetical protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"BEE12_03720 polyketide synthase\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			},
			{
				"name":"BEE12_03725 fimbrial protein\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			},
			{
				"name":"BEE12_03740 fimbrial protein\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			},
			{
				"name":"BEE12_21945 spore coat protein U\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			},
			{
				"name":"BEE12_21950 spore coat protein U\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			}
			]
		},
		{
			"name":"P pilus assembly protein"
		},
		{
			"name":"Mat\/Ecp fimbriae assembly protein"
		}
		]
	},
	{
		"name":"Extracellular nucleation-precipitation pathway",
		"children":[
		{
			"name":"Curli assembly protein"
		}
		]
	},
	{
		"name":"Sec (secretion) system",
		"children":[
		{
			"name":"Prokaryotic Sec-SRP core components",
			"children":[
			{
				"name":"BEE12_10375 preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
			},
			{
				"name":"BEE12_06320 protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB"
			},
			{
				"name":"BEE12_11435 protein-export membrane protein SecD\tK03072 secD; preprotein translocase subunit SecD"
			},
			{
				"name":"BEE12_07825 preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE"
			},
			{
				"name":"BEE12_11440 protein-export membrane protein SecF\tK03074 secF; preprotein translocase subunit SecF"
			},
			{
				"name":"BEE12_09280 preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG"
			},
			{
				"name":"BEE12_10370 SecA regulator SecM\tK13301 secM; secretion monitor"
			},
			{
				"name":"BEE12_04820 preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY"
			},
			{
				"name":"BEE12_02620 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			},
			{
				"name":"BEE12_05510 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
			},
			{
				"name":"BEE12_11430 preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC"
			},
			{
				"name":"BEE12_07040 membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
			}
			]
		},
		{
			"name":"Prokaryotic Sec-SRP related proteins"
		},
		{
			"name":"Eukaryotic Sec-SRP protein",
			"children":[
			{
				"name":"BEE12_02620 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			}
			]
		}
		]
	},
	{
		"name":"Twin-arginine translocation (Tat) system",
		"children":[
		{
			"name":"Twin-arginine translocation (Tat) pathway protein",
			"children":[
			{
				"name":"BEE12_07680 preprotein translocase subunit TatA\tK03116 tatA; sec-independent protein translocase protein TatA"
			},
			{
				"name":"BEE12_07685 twin arginine-targeting protein translocase TatB\tK03117 tatB; sec-independent protein translocase protein TatB"
			},
			{
				"name":"BEE12_07690 twin arginine-targeting protein translocase TatC\tK03118 tatC; sec-independent protein translocase protein TatC"
			},
			{
				"name":"BEE12_12215 tatE; Sec-independent protein translocase TatE\tK03425 tatE; sec-independent protein translocase protein TatE"
			}
			]
		}
		]
	}
	]
}