{
	"name":"pant02048",
	"children":[
	{
		"name":"CRISPR-Cas system",
		"children":[
		{
			"name":"Universal Cas proteins"
		},
		{
			"name":"Type I CRISPR-Cas system",
			"children":[
			{
				"name":"Type I signiture cas proteins"
			},
			{
				"name":"Subtype I-A factors"
			},
			{
				"name":"Subtype I-B factors"
			},
			{
				"name":"Subtype I-C factors"
			},
			{
				"name":"Subtype I-D factors"
			},
			{
				"name":"Subtype I-E factors"
			},
			{
				"name":"Subtype I-F factors"
			},
			{
				"name":"Subtype I-U factors"
			}
			]
		},
		{
			"name":"Type II CRISPR-Cas system",
			"children":[
			{
				"name":"Type II signiture cas proteins"
			},
			{
				"name":"Subtype II-A factors"
			},
			{
				"name":"Subtype II-B factors"
			}
			]
		},
		{
			"name":"Type III CRISPR-Cas system",
			"children":[
			{
				"name":"Type III signiture cas proteins"
			},
			{
				"name":"Subtype III-A factors"
			},
			{
				"name":"Subtype III-B factors"
			},
			{
				"name":"Subtype III-U factors"
			}
			]
		}
		]
	},
	{
		"name":"Restriction and modification system (R-M system)",
		"children":[
		{
			"name":"Type I R-M system"
		},
		{
			"name":"Type II R-M system",
			"children":[
			{
				"name":"Restriction endonucleases"
			},
			{
				"name":"DNA methyltransferases",
				"children":[
				{
					"name":"PSNIH1_03220 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"PSNIH1_03430 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"PSNIH1_04615 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"PSNIH1_19550 DNA modification methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"PSNIH1_07895 restriction endonuclease SinI\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"PSNIH1_15490 DNA cytosine methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"PSNIH1_18580 modification methylase EcoRII\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"PSNIH1_20475 DNA cytosine methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			}
			]
		},
		{
			"name":"Type III R-M system"
		},
		{
			"name":"Type IV R-M system",
			"children":[
			{
				"name":"PSNIH1_18590 TetR family transcriptional regulator\tK07448 mrr; restriction system protein"
			}
			]
		}
		]
	},
	{
		"name":"Toxin-antitoxin system (TA system)",
		"children":[
		{
			"name":"Type I TA system",
			"children":[
			{
				"name":"Hok-Sok"
			},
			{
				"name":"SymE-SymR",
				"children":[
				{
					"name":"PSNIH1_09935 endoribonuclease symE\tK19048 symE; toxic protein SymE"
				}
				]
			},
			{
				"name":"Ldr-Rdl"
			},
			{
				"name":"TisB-IstR"
			},
			{
				"name":"Ibs-Sib"
			},
			{
				"name":"ShoB-OhsC"
			},
			{
				"name":"RalR-RalA"
			}
			]
		},
		{
			"name":"Type II TA system",
			"children":[
			{
				"name":"MazF-MazE"
			},
			{
				"name":"ChpB-ChpS"
			},
			{
				"name":"YhaV-PrlF",
				"children":[
				{
					"name":"PSNIH1_19265 hypothetical protein\tK19156 prlF; antitoxin PrlF"
				}
				]
			},
			{
				"name":"RelE\/StbE-RelB\/StbD",
				"children":[
				{
					"name":"PSNIH1_20080 RelE toxin\tK06218 relE; mRNA interferase RelE\/StbE"
				},
				{
					"name":"PSNIH1_p00025 RelE toxin\tK06218 relE; mRNA interferase RelE\/StbE"
				},
				{
					"name":"PSNIH1_20075 bifunctional antitoxin\/transcriptional repressor RelB\tK18918 relB; RHH-type transcriptional regulator, rel operon repressor \/ antitoxin RelB"
				},
				{
					"name":"PSNIH1_p00020 bifunctional antitoxin\/transcriptional repressor RelB\tK18918 relB; RHH-type transcriptional regulator, rel operon repressor \/ antitoxin RelB"
				}
				]
			},
			{
				"name":"YafQ-dinJ",
				"children":[
				{
					"name":"PSNIH1_19480 damage-inducible protein J\tK07473 dinJ; DNA-damage-inducible protein J"
				}
				]
			},
			{
				"name":"YoeB-YefM",
				"children":[
				{
					"name":"PSNIH1_p00135 toxin YoeB\tK19158 yoeB; toxin YoeB [EC:3.1.-.-]"
				},
				{
					"name":"PSNIH1_p00130 antitoxin YefM\tK19159 yefM; antitoxin YefM"
				}
				]
			},
			{
				"name":"HipA-HipB",
				"children":[
				{
					"name":"PSNIH1_05880 serine\/threonine protein kinase\tK07154 hipA; serine\/threonine-protein kinase HipA [EC:2.7.11.1]"
				},
				{
					"name":"PSNIH1_15855 toxin HipA\tK07154 hipA; serine\/threonine-protein kinase HipA [EC:2.7.11.1]"
				},
				{
					"name":"PSNIH1_05885 XRE family transcriptional regulator\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				},
				{
					"name":"PSNIH1_19930 transcriptional regulator\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				}
				]
			},
			{
				"name":"HicA-HicB"
			},
			{
				"name":"YafO-YafN"
			},
			{
				"name":"PspC-PspB",
				"children":[
				{
					"name":"PSNIH1_13840 transcriptional regulator\tK03973 pspC; phage shock protein C"
				},
				{
					"name":"PSNIH1_13845 pspB; phage shock protein\tK03970 pspB; phage shock protein B"
				}
				]
			},
			{
				"name":"CcdB-CcdA"
			},
			{
				"name":"ParE-ParD"
			},
			{
				"name":"Doc-Phd",
				"children":[
				{
					"name":"PSNIH1_19220 hypothetical protein\tK19165 phd; antitoxin Phd"
				}
				]
			},
			{
				"name":"HigB-HigA",
				"children":[
				{
					"name":"PSNIH1_p00820 Killer protein\tK07334 higB-1; toxin HigB-1"
				},
				{
					"name":"PSNIH1_p00815 XRE family transcriptional regulator\tK21498 higA-1; antitoxin HigA-1"
				}
				]
			},
			{
				"name":"MqsR-MqsA",
				"children":[
				{
					"name":"PSNIH1_19290 XRE family transcriptional regulator\tK13655 mqsA; HTH-type transcriptional regulator \/ antitoxin MqsA"
				}
				]
			},
			{
				"name":"VapC-VapB",
				"children":[
				{
					"name":"PSNIH1_p01300 hypothetical protein\tK28279 vapC22; ribonuclease VapC22 [EC:3.1.-.-]"
				},
				{
					"name":"PSNIH1_p01305 hypothetical protein\tK28280 vapB22; antitoxin VapB22"
				}
				]
			},
			{
				"name":"PezT-PezA"
			},
			{
				"name":"YobL-YobK"
			},
			{
				"name":"YokI-YokJ"
			},
			{
				"name":"YqcG-YqcF"
			},
			{
				"name":"YxiD-YxxD"
			},
			{
				"name":"FitB-FitA"
			},
			{
				"name":"BC_0920-BC_0921"
			},
			{
				"name":"SpoIISA-SpoIISB"
			},
			{
				"name":"Tse6-Tsi6"
			},
			{
				"name":"Type II TA system related factors",
				"children":[
				{
					"name":"PSNIH1_11745 bssS; biofilm formation regulatory protein BssS\tK12148 bssS; biofilm regulator BssS"
				},
				{
					"name":"PSNIH1_08420 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"PSNIH1_04105 rod shape-determining protein MreB\tK03569 mreB; rod shape-determining protein MreB and related proteins"
				},
				{
					"name":"PSNIH1_02925 DNA topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"PSNIH1_02950 DNA topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"PSNIH1_00900 gltX; glutamyl-tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				}
				]
			}
			]
		},
		{
			"name":"Type III TA system",
			"children":[
			{
				"name":"AbiQ system"
			}
			]
		},
		{
			"name":"Type IV TA system",
			"children":[
			{
				"name":"YeeV-YeeU"
			},
			{
				"name":"CptA-CptB",
				"children":[
				{
					"name":"PSNIH1_02385 hypothetical protein\tK19168 cptA; toxin CptA"
				},
				{
					"name":"PSNIH1_02390 hypothetical protein\tK09159 cptB; antitoxin CptB"
				}
				]
			},
			{
				"name":"AbiEii-AbiEi"
			}
			]
		},
		{
			"name":"Type V TA system",
			"children":[
			{
				"name":"GhoT-GhoS"
			},
			{
				"name":"Other GhoT\/OrtT toxin family protein"
			}
			]
		},
		{
			"name":"Type VI TA system",
			"children":[
			{
				"name":"SocB-SocA"
			}
			]
		},
		{
			"name":"Type VII TA system",
			"children":[
			{
				"name":"Hha-TomB",
				"children":[
				{
					"name":"PSNIH1_09670 gene expression modulator\tK05839 hha; haemolysin expression modulating protein"
				},
				{
					"name":"PSNIH1_19830 regulatory protein\tK05839 hha; haemolysin expression modulating protein"
				},
				{
					"name":"PSNIH1_09675 Hha toxicity attenuator\tK19162 tomB; hha toxicity modulator TomB"
				}
				]
			},
			{
				"name":"TglT-TakA"
			},
			{
				"name":"HepT-MntA"
			}
			]
		},
		{
			"name":"Type VIII TA system",
			"children":[
			{
				"name":"SdsR-RyeA"
			}
			]
		}
		]
	},
	{
		"name":"DNA phosphothiolation system",
		"children":[
		{
			"name":"Sulfur modification proteins",
			"children":[
			{
				"name":"PSNIH1_01390 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
			}
			]
		},
		{
			"name":"DNA phosphorothioation-dependent restriction proteins"
		}
		]
	}
	]
}