{
	"name":"pcoc03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"116226227 RNMT; mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"116240660 RNGTT; mRNA-capping enzyme isoform X1\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]"
					},
					{
						"name":"116239926 CDK7; cyclin-dependent kinase 7 isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"116229522 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					},
					{
						"name":"116243878 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]"
					},
					{
						"name":"116225345 RAMAC; RNA guanine-N7 methyltransferase activating subunit isoform X1\tK18708 FAM103A1; RNMT-activating mini protein"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"116239466 NCBP1; nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"116229604 nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					},
					{
						"name":"116230870 LOW QUALITY PROTEIN: nuclear cap-binding protein subunit 2-like\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"116243582 NUDT21; cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"116226590 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					},
					{
						"name":"116243028 CPSF7; cleavage and polyadenylation specificity factor subunit 7\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"116229070 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"116241931 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"116239770 LOW QUALITY PROTEIN: cleavage and polyadenylation specificity factor subunit 1-like\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"116228900 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"116240406 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"116237461 CPSF4; cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"116225912 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"116229738 pre-mRNA 3'-end-processing factor FIP1-like isoform X1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"116236376 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"116241060 WDR82; WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"116228591 PPP1CC; serine\/threonine-protein phosphatase PP1-gamma catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"116229780 PPP1CB; serine\/threonine-protein phosphatase PP1-beta catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"116243020 PPP1CA; serine\/threonine-protein phosphatase PP1-alpha catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"116242648 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"116244552 CSTF1; cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"116229659 CSTF2; cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"116237948 CSTF3; cleavage stimulation factor subunit 3\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"116225493 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B'\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"116228467 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"116237003 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"116233246 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"116231313 SNRPG; small nuclear ribonucleoprotein G isoform X1\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"116230020 LSM10; U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10"
					},
					{
						"name":"116232104 LSM11; U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11"
					},
					{
						"name":"116228900 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"116240406 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"116229659 CSTF2; cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"116225732 histone RNA hairpin-binding protein-like\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"116225733 uncharacterized protein LOC116225733\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"116240431 CASP8AP2; CASP8-associated protein 2\tK25593 CASP8AP2; CASP8-associated protein 2"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"116228220 SUPT4H1; transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"116237774 SUPT5H; transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"116239395 METTL3; N6-adenosine-methyltransferase catalytic subunit isoform X1\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]"
					},
					{
						"name":"116231247 METTL14; N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"116226175 METTL4; N(6)-adenine-specific DNA methyltransferase METTL4\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"116242295 METTL16; RNA N6-adenosine-methyltransferase METTL16\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"116241945 WTAP; pre-mRNA-splicing regulator WTAP isoform X1\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"116227611 VIRMA; protein virilizer homolog\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"116232295 RBM15B; putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"116236978 RBM15; RNA-binding protein 15\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"116244271 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"116232926 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"116228868 PAPOLA; poly(A) polymerase alpha isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"116230200 PAPOLG; poly(A) polymerase gamma isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"116239929 TENT2; poly(A) RNA polymerase GLD2 isoform X1\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]"
					},
					{
						"name":"116237749 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"116236061 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"116240022 RBM26; RNA-binding protein 26 isoform X1\tK13192 RBM26; RNA-binding protein 26"
					},
					{
						"name":"116243759 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X1\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"116237559 ALKBH5; RNA demethylase ALKBH5\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"116242634 TARDBP; TAR DNA-binding protein 43\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"116227968 DHX40; probable ATP-dependent RNA helicase DHX40\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]"
				},
				{
					"name":"116226622 KIN; DNA\/RNA-binding protein KIN17 isoform X1\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"116232863 METTL8; LOW QUALITY PROTEIN: mRNA N(3)-methylcytidine methyltransferase METTL8\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]"
				},
				{
					"name":"116237391 METTL22; methyltransferase-like protein 22\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"116230105 TENT5B; terminal nucleotidyltransferase 5B\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"116240499 TENT5A; terminal nucleotidyltransferase 5A isoform X1\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"116242413 TENT5C; terminal nucleotidyltransferase 5C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"116229689 terminal nucleotidyltransferase 5C-like\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]"
				},
				{
					"name":"116228926 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X1\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"116241275 RBM8A; RNA-binding protein 8A\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"116234886 MAGOH; protein mago nashi homolog\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"116232560 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"116231462 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"116237821 CCDC174; LOW QUALITY PROTEIN: coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"116233641 CASC3; protein CASC3 isoform X1\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"116244180 SAP18; histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"116229379 PNN; pinin\tK13114 PNN; pinin"
					},
					{
						"name":"116230318 RNPS1; RNA-binding protein with serine-rich domain 1\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"116230063 SRRM1; serine\/arginine repetitive matrix protein 1 isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"116242276 THOC1; THO complex subunit 1 isoform X1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"116234901 THOC2; THO complex subunit 2\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"116232092 THOC3; THO complex subunit 3\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"116232560 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"116228348 THOC5; THO complex subunit 5 homolog isoform X1\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"116237244 THOC7; THO complex subunit 7 homolog\tK13176 THOC7; THO complex subunit 7"
					},
					{
						"name":"116239562 CHTOP; chromatin target of PRMT1 protein isoform X1\tK28424 CHTOP; chromatin target of PRMT1 protein"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"116242809 PCID2; PCI domain-containing protein 2\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"116243261 SEM1; 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"116227683 ENY2; transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"116229719 CETN2; centrin-2\tK10840 CETN2; centrin-2"
					},
					{
						"name":"116238128 CETN3; centrin-3 isoform X1\tK16466 CETN3; centrin-3"
					},
					{
						"name":"116236012 MCM3AP; germinal-center associated nuclear protein\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"116238675 TPR; nucleoprotein TPR isoform X1\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"116244651 RAE1; mRNA export factor isoform X1\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"116236562 SEC13; protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"116226784 NUP37; nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"116232354 NUP85; nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"116241438 NUP43; nucleoporin Nup43 isoform X1\tK14305 NUP43; nuclear pore complex protein Nup43"
					},
					{
						"name":"116231453 NUP50; nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"116231167 NUP54; nucleoporin p54 isoform X1\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"116229552 NUP62CL; nucleoporin-62 C-terminal-like protein isoform X1\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"116228171 NUP88; nuclear pore complex protein Nup88\tK14318 NUP88; nuclear pore complex protein Nup88"
					},
					{
						"name":"116243945 NUP93; nuclear pore complex protein Nup93\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"116232709 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X1\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"116226599 NUP107; nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"116242785 NUP133; nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"116234225 NUP188; nucleoporin NUP188 homolog isoform X1\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"116226467 NUP153; nuclear pore complex protein Nup153 isoform X1\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"116229806 NUP155; nuclear pore complex protein Nup155 isoform X1\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"116237850 NUP160; nuclear pore complex protein Nup160\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"116235925 NUP35; nucleoporin NUP35\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"116233465 NUP205; nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"116237311 NUP210L; nuclear pore membrane glycoprotein 210-like isoform X1\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"116238814 NUP210; nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"116234256 NUP214; nuclear pore complex protein Nup214 isoform X1\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"116227873 nuclear envelope pore membrane protein POM 121-like\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"116244264 NUP58; nucleoporin p58\/p45 isoform X1\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"116227036 NUP42; nucleoporin NUP42\tK14321 NUPL2; nucleoporin-like protein 2"
					},
					{
						"name":"116234977 NDC1; LOW QUALITY PROTEIN: nucleoporin NDC1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"116226222 SEH1L; nucleoporin SEH1 isoform X1\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"116236505 RGPD4; ranBP2-like and GRIP domain-containing protein 4 isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
					},
					{
						"name":"116231010 SENP2; sentrin-specific protease 2 isoform X1\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
					},
					{
						"name":"116234937 AAAS; aladin isoform X1\tK14320 AAAS; aladin"
					},
					{
						"name":"116238128 CETN3; centrin-3 isoform X1\tK16466 CETN3; centrin-3"
					},
					{
						"name":"116234210 GLE1; nucleoporin GLE1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"116229781 NXT2; NTF2-related export protein 2 isoform X1\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"116228672 RAN; GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"116225488 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"116236112 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B"
					},
					{
						"name":"116236183 ELAVL1; ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"116234517 ELAVL4; ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"116239425 ELAVL2; ELAV-like protein 2 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"116243075 ELAVL3; ELAV-like protein 3\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"116232083 FAF2; FAS-associated factor 2\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"116239150 VCP; transitional endoplasmic reticulum ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"116240247 transitional endoplasmic reticulum ATPase isoform X1\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"116234624 VCPKMT; protein-lysine methyltransferase METTL21D\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]"
					},
					{
						"name":"116243080 TNPO2; LOW QUALITY PROTEIN: transportin-2\tK18727 TNPO2; transportin-2"
					},
					{
						"name":"116230191 XPO1; exportin-1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"116234558 XPO7; exportin-7 isoform X1\tK18460 XPO7; exportin-7"
					},
					{
						"name":"116233386 RANGAP1; ran GTPase-activating protein 1 isoform X1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"116228143 TAF15; TATA-binding protein-associated factor 2N isoform X1\tK14651 TAF15; transcription initiation factor TFIID subunit 15"
					},
					{
						"name":"116243833 NUTF2; nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"116231903 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"116235386 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"116239118 EIF4E; eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"116235417 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"116235403 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"116238358 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"116242906 EIF4G2; eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"116235221 EIF4B; eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"116228189 EIF4H; eukaryotic translation initiation factor 4H isoform X1\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"116234537 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1"
					},
					{
						"name":"116235111 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 isoform X1\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2"
					},
					{
						"name":"116228445 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"116228965 ANGEL1; protein angel homolog 1 isoform X1\tK18729 ANGEL; protein angel"
					},
					{
						"name":"116230468 ANGEL2; LOW QUALITY PROTEIN: protein angel homolog 2\tK18729 ANGEL; protein angel"
					},
					{
						"name":"116234849 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"116243415 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"116230802 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"116232107 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"116232114 GEMIN5; gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"116225736 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"116225806 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116231757 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116232047 CPEB4; cytoplasmic polyadenylation element-binding protein 4\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116244506 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116229852 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"116236359 GIGYF2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"116227574 PABPC1L; polyadenylate-binding protein 1-like isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"116227651 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"116229944 PABPC4; polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"116239111 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"116225649 PAIP2B; polyadenylate-binding protein-interacting protein 2B\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"116231959 PAIP2; polyadenylate-binding protein-interacting protein 2 isoform X1\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"116238719 SKIV2L; helicase SKI2W isoform X1\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"116237804 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform X1\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"116234899 MCTS1; malignant T-cell-amplified sequence 1\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"116228622 DENR; density-regulated protein\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex",
					"children":[
					{
						"name":"116234800 A1CF; APOBEC1 complementation factor isoform X1\tK24978 A1CF; APOBEC1 complementation factor"
					}
					]
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"116239270 PYM1; partner of Y14 and mago\tK14294 WIBG; partner of Y14 and mago"
					},
					{
						"name":"116234059 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"116234952 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"116227920 MSI2; RNA-binding protein Musashi homolog 2 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"116228420 MSI1; RNA-binding protein Musashi homolog 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"116235786 DAZAP1; DAZ-associated protein 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"116240394 HBS1L; HBS1-like protein isoform X1\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"116239357 PELO; protein pelota homolog\tK06965 PELO; protein pelota"
					},
					{
						"name":"116243927 PABPN1L; embryonic polyadenylate-binding protein 2\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"116242731 ATP-dependent RNA helicase DDX19B isoform X1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"116232798 ATP-dependent RNA helicase DDX25-like isoform X1\tK18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]"
					},
					{
						"name":"116235209 SARNP; SAP domain-containing ribonucleoprotein isoform X1\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"116230092 RCC1; regulator of chromosome condensation\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"116236098 la-related protein 6-like\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"116244637 LARP6; la-related protein 6 isoform X1\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"116241192 PURA; transcriptional activator protein Pur-alpha\tK21772 PURA; transcriptional activator protein Pur-alpha"
					},
					{
						"name":"116231299 PURB; transcriptional activator protein Pur-beta\tK21799 PURB; transcriptional activator protein Pur-beta"
					},
					{
						"name":"116233416 POLDIP3; polymerase delta-interacting protein 3 isoform X1\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"116238721 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform X1\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"116239628 LENG8; leukocyte receptor cluster member 8\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					},
					{
						"name":"116244502 PATL2; protein PAT1 homolog 2 isoform X1\tK24823 PATL2; protein PAT1 homolog 2"
					},
					{
						"name":"116229613 UAP56-interacting factor-like isoform X1\tK28772 FYTTD1; UAP56-interacting factor"
					},
					{
						"name":"116235360 FYTTD1; UAP56-interacting factor\tK28772 FYTTD1; UAP56-interacting factor"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"116231967 ETF1; eukaryotic peptide chain release factor subunit 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"116237579 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"116235731 UPF1; regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"116237875 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"116234889 UPF3B; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"116236499 UPF3A; regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"116232217 PPP2CA; serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"116238029 PPP2CB; serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"116225784 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"116231516 PPP2R2D; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"116232273 PPP2R2B; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"116238391 PPP2R2A; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"116229363 PPP2R3C; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"116230794 PPP2R3B; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"116231037 PPP2R3A; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"116228842 PPP2R5C; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"116230345 PPP2R5A; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"116235295 PPP2R5D; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"116236797 PPP2R5E; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"116237577 SMG1; serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"116238819 SMG5; protein SMG5\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"116228077 SMG6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"116230404 SMG7; protein SMG7 isoform X1\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"116227974 SMG8; protein SMG8\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"116236359 GIGYF2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"116225317 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"116236683 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"116233349 GTPBP1; GTP-binding protein 1 isoform X1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"116240132 PUM3; pumilio homolog 3\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"116236158 unconventional myosin-Vb-like\tK10357 MYO5; myosin V"
					},
					{
						"name":"116244682 MYO5A; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"116244683 MYO5C; unconventional myosin-Vc\tK10357 MYO5; myosin V"
					},
					{
						"name":"116226838 BICD1; protein bicaudal D homolog 1 isoform X1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"116238628 BICD2; protein bicaudal D homolog 2 isoform X1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"116229199 EXD1; piRNA biogenesis protein EXD1\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"116232509 ACTG1; actin, cytoplasmic 2\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"116237546 ACTB; actin, cytoplasmic 1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"116244547 actin, cytoplasmic type 5 isoform X1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"116226256 MBP; myelin basic protein isoform X1\tK17269 MBP; myelin basic protein"
					},
					{
						"name":"116243216 VIM; vimentin\tK07606 VIM; vimentin"
					},
					{
						"name":"116243757 metallothionein-1\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"116235733 GDF1; embryonic growth\/differentiation factor 1\tK05495 GDF1; growth differentiation factor 1"
					},
					{
						"name":"116228286 T-box-containing protein TBX6L\tK10180 TBX6; T-box protein 6"
					},
					{
						"name":"116231584 NANOS1; nanos homolog 1\tK18741 NANOS1; protein nanos 1"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"116233459 FUBP1; far upstream element-binding protein 1 isoform X1\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"116234252 FUBP3; far upstream element-binding protein 3 isoform X1\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"116227862 EEF1A2; elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"116240445 EEF1A1; elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"116227053 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2\/B1 isoform X1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1"
					},
					{
						"name":"116237316 HAX1; HCLS1-associated protein X-1\tK16220 HAX1; HCLS1-associated protein X-1"
					},
					{
						"name":"116230905 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"116227226 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"116236262 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"116227034 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3"
					},
					{
						"name":"116235818 PTBP1; polypyrimidine tract-binding protein 1 isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"116225806 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116231757 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116232047 CPEB4; cytoplasmic polyadenylation element-binding protein 4\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116244506 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"116234849 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"116243415 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"116230802 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"116232107 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"116234939 PCBP2; poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"116226304 poly(rC)-binding protein 3-like isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"116236019 PCBP3; poly(rC)-binding protein 3\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"116241066 PCBP4; poly(rC)-binding protein 4 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"116229102 CAPRIN1; caprin-1 isoform X1\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"116226844 CAPRIN2; caprin-2 isoform X1\tK18744 CAPRIN2; caprin-2"
					},
					{
						"name":"116238333 YBX1; Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"116230884 XRN1; 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"116227772 AGO2; protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"116230003 AGO4; protein argonaute-4 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"116230004 protein argonaute-1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"116230005 protein argonaute-3\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"116231903 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"116235386 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"116239118 EIF4E; eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"116235731 UPF1; regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"116229852 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"116233188 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"116225358 MEX3B; RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"116235846 MEX3D; RNA-binding protein MEX3D\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"116239144 MEX3A; RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"116242826 FASTK; fas-activated serine\/threonine kinase isoform X1\tK08290 FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]"
					},
					{
						"name":"116227084 LSM14B; protein LSM14 homolog B isoform X1\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"116243658 LSM14A; protein LSM14 homolog A isoform X1\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"116234939 PCBP2; poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"116238333 YBX1; Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"116227195 LIMD1; LIM domain-containing protein 1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"116243957 WTIP; Wilms tumor protein 1-interacting protein\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"116236878 MOV10; helicase MOV-10\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"116229932 PNRC2; proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2"
					},
					{
						"name":"116234820 TNPO1; transportin-1\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"116237577 SMG1; serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"116238819 SMG5; protein SMG5\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"116228077 SMG6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"116230404 SMG7; protein SMG7 isoform X1\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"116229280 ZFP36L1; mRNA decay activator protein ZFP36L1\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"116230029 ZFP36L2; mRNA decay activator protein ZFP36L2\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"116230171 LIN28A; protein lin-28 homolog A\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"116240388 LIN28B; protein lin-28 homolog B isoform X1\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"116225762 HTT; huntingtin isoform X1\tK04533 HD; huntingtin"
					},
					{
						"name":"116226845 IPO8; importin-8 isoform X1\tK18755 IPO8; importin-8"
					},
					{
						"name":"116238811 BICC1; protein bicaudal C homolog 1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"116234059 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"116234952 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"116233372 PRKACB; cAMP-dependent protein kinase catalytic subunit beta\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"116239748 LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit beta-like\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"116232119 LARP1; la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"116237999 LARP1B; la-related protein 1B isoform X1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"116228579 ATXN2; ataxin-2 isoform X1\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"116239719 DCP2; m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"116238603 DCP1A; mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"116226869 DCP1B; mRNA-decapping enzyme 1B isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"116234536 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"116237912 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"116235722 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"116238599 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"116226124 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"116240197 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"116243896 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"116228811 KLC1; kinesin light chain 1 isoform X1\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"116235291 KLC4; kinesin light chain 4 isoform X1\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"116236158 unconventional myosin-Vb-like\tK10357 MYO5; myosin V"
					},
					{
						"name":"116244682 MYO5A; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"116244683 MYO5C; unconventional myosin-Vc\tK10357 MYO5; myosin V"
					},
					{
						"name":"116226768 tubulin alpha-4 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"116226877 tubulin alpha-2 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"116232958 TUBA4A; tubulin alpha-4A chain isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"116235428 tubulin alpha-3 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"116236468 tubulin alpha-3 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"116238732 tubulin alpha-8 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"116239280 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"116225806 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116231757 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116232047 CPEB4; cytoplasmic polyadenylation element-binding protein 4\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116244506 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"116232114 GEMIN5; gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"116225736 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"116232630 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"116233371 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"116237676 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"116244032 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"116226582 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"116233462 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"116232177 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"116238074 CNOT6L; CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"116225939 CNOT7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"116232115 CNOT8; CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"116243657 uncharacterized protein KIAA0355 homolog\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1"
					},
					{
						"name":"116235380 DIS3L2; DIS3-like exonuclease 2 isoform X1\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"116239817 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"116244138 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"116232398 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116233185 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116233390 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116233509 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116236997 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116239252 protein BTG1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116228445 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"116242882 PATL1; protein PAT1 homolog 1 isoform X1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"116225553 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"116243782 EDC4; enhancer of mRNA-decapping protein 4 isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"116237875 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"116234889 UPF3B; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"116236499 UPF3A; regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"116227136 TRIM71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"116229008 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]"
					},
					{
						"name":"116225979 ZAR1; zygote arrest protein 1\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"116244246 ZAR1L; ZAR1-like protein\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"116226866 YTHDF1; YTH domain-containing family protein 1 isoform X1\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"116230082 YTHDF2; YTH domain-containing family protein 2\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"116242274 YTHDF3; YTH domain-containing family protein 3\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"116231309 TIA1; nucleolysin TIA-1 isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"116231576 TIAL1; nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"116227574 PABPC1L; polyadenylate-binding protein 1-like isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"116227651 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"116229944 PABPC4; polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"116227226 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"116236262 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"116234849 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"116243415 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"116236183 ELAVL1; ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"116232128 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"116231079 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"116235439 EIF2A; eukaryotic translation initiation factor 2A\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"116237393 EIF3B; eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"116235417 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"116231462 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"116235221 EIF4B; eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"116235403 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"116238358 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"116242906 EIF4G2; eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"116229679 RPS6KA6; ribosomal protein S6 kinase alpha-6\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"116230155 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"116232754 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"116242257 RPS6KA2; ribosomal protein S6 kinase alpha-2\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"116236721 RACK1; receptor of activated protein C kinase 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"116234112 TRAF2; TNF receptor-associated factor 2 isoform X1\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
					},
					{
						"name":"116243329 TDRD3; tudor domain-containing protein 3 isoform X1\tK18404 TDRD3; tudor domain-containing protein 3"
					},
					{
						"name":"116239677 LARP4; la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4"
					},
					{
						"name":"116244369 LARP4B; la-related protein 4B isoform X1\tK18763 LARP4; la-related protein 4"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"116238603 DCP1A; mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"116226869 DCP1B; mRNA-decapping enzyme 1B isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"116239719 DCP2; m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"116233188 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"116225553 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"116243782 EDC4; enhancer of mRNA-decapping protein 4 isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"116242882 PATL1; protein PAT1 homolog 1 isoform X1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"116234536 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"116237912 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"116235722 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"116238599 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"116226124 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"116240197 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"116243896 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"116230884 XRN1; 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"116235309 XRN2; 5'-3' exoribonuclease 2 isoform X1\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"116240186 U8 snoRNA-decapping enzyme-like\tK16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"116233046 DCPS; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"116232460 HELZ; probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"116231715 EXOSC1; exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"116234253 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"116234726 EXOSC3; exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"116239678 EXOSC4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"116238693 EXOSC5; exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"116243820 EXOSC6; exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"116227199 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"116244229 EXOSC8; exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"116231227 EXOSC9; exosome complex component RRP45 isoform X1\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"116236976 DIS3; exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"116225468 DIS3L; DIS3-like exonuclease 1\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"116242611 EXOSC10; exosome component 10\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"116235271 C1D; nuclear nucleic acid-binding protein C1D isoform X1\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"116244060 MPHOSPH6; M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					},
					{
						"name":"116242849 DDX60; probable ATP-dependent RNA helicase DDX60\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"116226343 TENT4A; terminal nucleotidyltransferase 4A isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"116244023 TENT4B; terminal nucleotidyltransferase 4B\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"116239442 ZCCHC7; zinc finger CCHC domain-containing protein 7\tK12597 AIR1_2; protein AIR1\/2"
					},
					{
						"name":"116239411 MTREX; exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"116238719 SKIV2L; helicase SKI2W isoform X1\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"116236583 TTC37; tetratricopeptide repeat protein 37\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"116244594 WDR61; WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"116232177 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"116238074 CNOT6L; CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"116244032 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"116226582 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"116233462 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"116225939 CNOT7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"116232115 CNOT8; CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"116227319 CNOT9; CCR4-NOT transcription complex subunit 9 isoform X1\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"116227135 CNOT10; CCR4-NOT transcription complex subunit 10 isoform X1\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"116239817 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"116244138 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"116237548 PARN; poly(A)-specific ribonuclease PARN isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"116241999 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"116235455 DHX36; ATP-dependent DNA\/RNA helicase DHX36\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"116232398 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116233185 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116233390 TOB2; protein Tob2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116233509 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116236997 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116239252 protein BTG1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"116226093 NOCT; nocturnin\tK18764 NOCT; nocturnin [EC:3.1.3.108]"
					},
					{
						"name":"116231156 ERI1; 3'-5' exoribonuclease 1 isoform X1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"116230341 ERI2; ERI1 exoribonuclease 2\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]"
					},
					{
						"name":"116233046 DCPS; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"116238438 PDE12; 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"116244590 IREB2; iron-responsive element-binding protein 2\tK22416 IREB2; iron-responsive element-binding protein 2"
					},
					{
						"name":"116232460 HELZ; probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"116226366 HELZ2; helicase with zinc finger domain 2\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]"
					},
					{
						"name":"116228917 NRDE2; nuclear exosome regulator NRDE2\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"116236658 SAMD4A; protein Smaug homolog 1 isoform X1\tK27396 SMG; protein Smaug"
					},
					{
						"name":"116237780 SAMD4B; protein Smaug homolog 2 isoform X1\tK27396 SMG; protein Smaug"
					},
					{
						"name":"116239797 FOCAD; focadhesin\tK27498 FOCAD; focadhesin"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases",
					"children":[
					{
						"name":"116229470 ZC3H12B; probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"116230022 ZC3H12A; endoribonuclease ZC3H12A\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"116237184 ZC3H12C; probable ribonuclease ZC3H12C\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"116241563 ZC3H12D; probable ribonuclease ZC3H12D\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"116226380 DROSHA; ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"116233145 REXO2; oligoribonuclease, mitochondrial\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"116239950 ENO2; gamma-enolase isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"116242528 ENO1; alpha-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"116231821 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"116231014 PFKL; ATP-dependent 6-phosphofructokinase, liver type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"116234930 PFKM; ATP-dependent 6-phosphofructokinase, muscle type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"116244376 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"116231965 HSPA9; stress-70 protein, mitochondrial\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"116233952 HSPD1; 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"116234253 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"116231715 EXOSC1; exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"116239678 EXOSC4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"116227199 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}