{
	"name":"pdf04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"CD630DERM_02730 htpG; Heat shock protein 90 (Heat shock proteinHtpG)(High temperature protein G)\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"CD630DERM_31700 eno; Enolase (2-phosphoglycerate dehydratase)(2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"CD630DERM_31740 gapA; Glyceraldehyde-3-phosphate dehydrogenase(GAPDH)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"CD630DERM_31730 pgk; Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"CD630DERM_33940 pyk; Pyruvate kinase (PK)\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"CD630DERM_16460 putative peptidase, M19 family\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"CD630DERM_28620 putative peptidase, M19 family\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"CD630DERM_35700 putative peptidase, M19 family\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"CD630DERM_01940 groL; 60 kDa chaperonin (Protein Cpn60) (GroELprotein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"CD630DERM_24610 dnaK; Chaperone protein dnaK (Heat shock protein 70)(Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"CD630DERM_32850 pgi; Glucose-6-phosphate isomerase (GPI)(Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase)(PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"CD630DERM_23350 guaB; Inositol-5'-monophosphate dehydrogenase (IMPdehydrogenase) (IMPDH) (IMPD)\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"CD630DERM_00580 tuf1; Elongation factor EFTu\/EF1A\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"CD630DERM_00710 tuf; Elongation factor EFTu\/EF1A (EF-Tu)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"CD630DERM_24470 putative histidine triad (HIT) protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells",
			"children":[
			{
				"name":"CD630DERM_21640 ldh; L-lactate dehydrogenase (L-LDH)\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
			}
			]
		},
		{
			"name":"Exosomal proteins of hepatic cells"
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"CD630DERM_21640 ldh; L-lactate dehydrogenase (L-LDH)\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"CD630DERM_01940 groL; 60 kDa chaperonin (Protein Cpn60) (GroELprotein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"CD630DERM_10590 thlA1; Acetoacetyl-CoA thiolase 1\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"CD630DERM_26760 thlA2; Acetoacetyl-CoA thiolase 2\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"CD630DERM_29700 putative thiolase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"CD630DERM_00910 adk; Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"CD630DERM_27450 apt; Adenine phosphoribosyltransferase (APRT)\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"CD630DERM_25000 argH; Argininosuccinate lyase (Arginosuccinase)(ASAL)\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"CD630DERM_17850 argG; Argininosuccinate synthase(Citrulline--aspartate ligase)\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"CD630DERM_20830 D-hydantoinase (Dihydropyrimidinase)\tK01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]"
			},
			{
				"name":"CD630DERM_31780 D-hydantoinase (Dihydropyrimidinase)\tK01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]"
			},
			{
				"name":"CD630DERM_25260 glgB; 1,4-alpha-glucan branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
			},
			{
				"name":"CD630DERM_07410 glpK1; Glycerol kinase (GK)\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"CD630DERM_13820 glpK2; Glycerol kinase 1 (ATP:glycerol3-phosphotransferase 1) (Glycerokinase 1) (GK 1)\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"CD630DERM_13430 glnA; Glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"CD630DERM_32850 pgi; Glucose-6-phosphate isomerase (GPI)(Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase)(PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"CD630DERM_34190 hemB; Delta-aminolevulinic acid dehydratase(porphobilinogen synthase)\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"CD630DERM_09950 serA; putative D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"CD630DERM_02230 purH; Bifunctional purine biosynthesis protein purH[Includes: Phosphoribosylaminoimidazolecarboxamideformyltransferase; IMP cyclohydrolase]\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			},
			{
				"name":"CD630DERM_08410 5-aminoimidazole-4-carboxamide ribonucleotidetransformylase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"CD630DERM_00390 acoL; Acetoin dehydrogenase E3 component(dihydrolipoamide dehydrogenase)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"CD630DERM_07230 Bifunctional carbon monoxidedehydrogenase\/acetyl-CoA synthase, dihydrolipoyldehydrogenase subunit\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"CD630DERM_08050 etfA2; Electron transfer flavoprotein alpha-subunit\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"CD630DERM_10560 etfA3; Electron transfer flavoprotein subunit alpha\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"CD630DERM_23350 guaB; Inositol-5'-monophosphate dehydrogenase (IMPdehydrogenase) (IMPDH) (IMPD)\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"CD630DERM_24610 dnaK; Chaperone protein dnaK (Heat shock protein 70)(Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"CD630DERM_01940 groL; 60 kDa chaperonin (Protein Cpn60) (GroELprotein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"CD630DERM_00580 tuf1; Elongation factor EFTu\/EF1A\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"CD630DERM_00710 tuf; Elongation factor EFTu\/EF1A (EF-Tu)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"CD630DERM_01940 groL; 60 kDa chaperonin (Protein Cpn60) (GroELprotein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"CD630DERM_32850 pgi; Glucose-6-phosphate isomerase (GPI)(Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase)(PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"CD630DERM_24610 dnaK; Chaperone protein dnaK (Heat shock protein 70)(Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"CD630DERM_31720 tpi; Triosephosphate isomerase (TIM)(Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"CD630DERM_00580 tuf1; Elongation factor EFTu\/EF1A\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"CD630DERM_00710 tuf; Elongation factor EFTu\/EF1A (EF-Tu)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"CD630DERM_01940 groL; 60 kDa chaperonin (Protein Cpn60) (GroELprotein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"CD630DERM_31720 tpi; Triosephosphate isomerase (TIM)(Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"CD630DERM_31720 tpi; Triosephosphate isomerase (TIM)(Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}