{
	"name":"pgri01009",
	"children":[
	{
		"name":"Protein serine\/threonine phosphatases",
		"children":[
		{
			"name":"Phosphoprotein phosphatases (PPPs)",
			"children":[
			{
				"name":"Protein phosphatase-1",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"PgNI_04599 uncharacterized protein\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"PgNI_11713 uncharacterized protein\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP1-interacting proteins (PIPs)",
					"children":[
					{
						"name":"PgNI_01506 uncharacterized protein\tK16833 PPP1R2; protein phosphatase inhibitor 2"
					},
					{
						"name":"PgNI_00349 uncharacterized protein\tK17550 PPP1R7; protein phosphatase 1 regulatory subunit 7"
					},
					{
						"name":"PgNI_08134 uncharacterized protein\tK17553 PPP1R11; protein phosphatase 1 regulatory subunit 11"
					},
					{
						"name":"PgNI_00404 uncharacterized protein\tK17560 URI1; unconventional prefoldin RPB5 interactor 1"
					},
					{
						"name":"PgNI_02192 uncharacterized protein\tK14806 DDX31; ATP-dependent RNA helicase DDX31\/DBP7 [EC:5.6.2.7]"
					},
					{
						"name":"PgNI_09720 uncharacterized protein\tK13099 CD2BP2; CD2 antigen cytoplasmic tail-binding protein 2"
					},
					{
						"name":"PgNI_04954 uncharacterized protein\tK11498 CENPE; centromeric protein E"
					},
					{
						"name":"PgNI_08503 uncharacterized protein\tK03238 EIF2S2; translation initiation factor 2 subunit 2"
					},
					{
						"name":"PgNI_04345 uncharacterized protein\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"PgNI_06776 uncharacterized protein\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"PgNI_08165 uncharacterized protein\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"PgNI_09606 uncharacterized protein\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
					},
					{
						"name":"PgNI_01446 uncharacterized protein\tK11446 KDM5; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]"
					},
					{
						"name":"PgNI_03314 uncharacterized protein\tK02932 RP-L5e; large subunit ribosomal protein L5e"
					},
					{
						"name":"PgNI_06269 mini-chromosome maintenance complex protein 7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
					},
					{
						"name":"PgNI_07683 uncharacterized protein\tK14559 MPP10; U3 small nucleolar RNA-associated protein MPP10"
					},
					{
						"name":"PgNI_08606 uncharacterized protein\tK10356 MYO1; myosin I"
					},
					{
						"name":"PgNI_10329 hypothetical protein\tK20872 NEK2; serine\/threonine-protein kinase Nek2 [EC:2.7.11.1]"
					},
					{
						"name":"PgNI_00446 uncharacterized protein\tK17583 NOM1; nucleolar MIF4G domain-containing protein 1"
					},
					{
						"name":"PgNI_09730 uncharacterized protein\tK02607 ORC5; origin recognition complex subunit 5"
					},
					{
						"name":"PgNI_10762 hypothetical protein\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"PgNI_09617 uncharacterized protein\tK14849 RRP1; ribosomal RNA-processing protein 1"
					},
					{
						"name":"PgNI_09931 uncharacterized protein\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"PgNI_02779 uncharacterized protein\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-2 (PP2A)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"PgNI_01773 uncharacterized protein\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"PgNI_03216 uncharacterized protein\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"PgNI_03257 uncharacterized protein\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"PgNI_06896 uncharacterized protein\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other PP2-interacting proteins",
					"children":[
					{
						"name":"PgNI_06343 hypothetical protein\tK17605 PPP2R4; serine\/threonine-protein phosphatase 2A activator"
					},
					{
						"name":"PgNI_11390 hypothetical protein\tK17605 PPP2R4; serine\/threonine-protein phosphatase 2A activator"
					},
					{
						"name":"PgNI_03962 uncharacterized protein\tK17606 IGBP1; immunoglobulin-binding protein 1"
					},
					{
						"name":"PgNI_08872 uncharacterized protein\tK17607 TIPRL; type 2A phosphatase activator TIP41"
					},
					{
						"name":"PgNI_01646 uncharacterized protein\tK17608 STRN1_3_4; striatin 1\/3\/4"
					},
					{
						"name":"PgNI_08587 uncharacterized protein\tK27960 STRIP; striatin-interacting protein"
					},
					{
						"name":"PgNI_03736 uncharacterized protein\tK18203 LCMT1; [phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233]"
					}
					]
				}
				]
			},
			{
				"name":"Calcineurin (PPP3\/ PP2B)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"PgNI_02414 uncharacterized protein\tK04348 PPP3C; serine\/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"PgNI_06015 hypothetical protein\tK06268 PPP3R; serine\/threonine-protein phosphatase 2B regulatory subunit"
					},
					{
						"name":"PgNI_05962 calmodulin\tK02183 CALM; calmodulin"
					}
					]
				},
				{
					"name":"Other calcineurin-interacting proteins"
				}
				]
			},
			{
				"name":"Protein phosphatase-4",
				"children":[
				{
					"name":"Catalytic subunits"
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"PgNI_01731 uncharacterized protein\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-5",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"PgNI_06024 hypothetical protein\tK04460 PPP5C; serine\/threonine-protein phosphatase 5 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP5-interacting proteins",
					"children":[
					{
						"name":"PgNI_09956 uncharacterized protein\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"PgNI_02429 uncharacterized protein\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"PgNI_05827 hypothetical protein\tK04079 HSP90A; molecular chaperone HtpG"
					},
					{
						"name":"PgNI_06044 hypothetical protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					},
					{
						"name":"PgNI_08633 uncharacterized protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-6",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"PgNI_07020 uncharacterized protein\tK15427 SIT4; serine\/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]"
					},
					{
						"name":"PgNI_03804 uncharacterized protein\tK17615 PPG1; serine\/threonine-protein phosphatase PPG1 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits"
				}
				]
			},
			{
				"name":"PPEF\/PP7 protein phosphatases"
			}
			]
		},
		{
			"name":"Mg2+- or Mn2+- dependent protein phosphatases (PPMs)",
			"children":[
			{
				"name":"PPM1 phosphatases (PP2C)",
				"children":[
				{
					"name":"PgNI_09544 uncharacterized protein\tK19704 PTC1; protein phosphatase PTC1 [EC:3.1.3.16]"
				},
				{
					"name":"PgNI_04287 uncharacterized protein\tK14803 PTC2_3; protein phosphatase PTC2\/3 [EC:3.1.3.16]"
				},
				{
					"name":"PgNI_07010 uncharacterized protein\tK19708 PTC6; protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43]"
				},
				{
					"name":"PgNI_11732 uncharacterized protein\tK17508 PTC7; protein phosphatase PTC7 [EC:3.1.3.16]"
				}
				]
			},
			{
				"name":"Pyruvate dehydrogenase phosphatases",
				"children":[
				{
					"name":"Catalytic subunit",
					"children":[
					{
						"name":"PgNI_09697 uncharacterized protein\tK01102 PDP; pyruvate dehydrogenase phosphatase [EC:3.1.3.43]"
					},
					{
						"name":"PgNI_07010 uncharacterized protein\tK19708 PTC6; protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43]"
					}
					]
				},
				{
					"name":"Regulatory subunit"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein tyrosine phosphatases (PTPs)",
		"children":[
		{
			"name":"Class I PTPs (Classical)",
			"children":[
			{
				"name":"Receptor PTPs"
			},
			{
				"name":"Non-receptor PTPs",
				"children":[
				{
					"name":"PgNI_04143 uncharacterized protein\tK19806 PTP2_3; tyrosine-protein phosphatase 2\/3 [EC:3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class I PTPs (Dual specificity phosphatases)",
			"children":[
			{
				"name":"MAPK phosphatases",
				"children":[
				{
					"name":"PgNI_09669 uncharacterized protein\tK04459 DUSP2S; dual specificity protein phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"PgNI_09531 uncharacterized protein\tK11240 MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"Slingshots"
			},
			{
				"name":"Phosphatase of regenerating liver (PRL)"
			},
			{
				"name":"Atypical DSPs",
				"children":[
				{
					"name":"PgNI_11905 uncharacterized protein\tK14819 DUSP12; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"PgNI_01708 uncharacterized protein\tK18042 STYX; serine\/threonine\/tyrosine-interacting protein"
				},
				{
					"name":"PgNI_07024 uncharacterized protein\tK18045 SIW14; tyrosine-protein phosphatase SIW14 [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"CDC14",
				"children":[
				{
					"name":"PgNI_02924 uncharacterized protein\tK06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]"
				}
				]
			},
			{
				"name":"Phosphatase and Tensin homologs (PTEN)"
			},
			{
				"name":"Myotubularins",
				"children":[
				{
					"name":"PgNI_03215 uncharacterized protein\tK18083 MTMR6_7_8; myotubularin-related protein 6\/7\/8 [EC:3.1.3.64 3.1.3.95]"
				}
				]
			},
			{
				"name":"Suppressors of T-cell receptor signaling"
			}
			]
		},
		{
			"name":"Class II PTPs",
			"children":[
			{
				"name":"Low molecular weight PTPs (LMWPTPs)",
				"children":[
				{
					"name":"PgNI_01374 uncharacterized protein\tK14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class III PTPs",
			"children":[
			{
				"name":"CDC25s",
				"children":[
				{
					"name":"PgNI_09332 uncharacterized protein\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"PgNI_12319 uncharacterized protein\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"HAD phosphatases",
		"children":[
		{
			"name":"Fcp\/Scp phosphatases",
			"children":[
			{
				"name":"PgNI_00545 uncharacterized protein\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"PgNI_00352 uncharacterized protein\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"PgNI_01884 uncharacterized protein\tK17617 CTDNEP1; CTD nuclear envelope phosphatase 1 [EC:3.1.3.16]"
			},
			{
				"name":"PgNI_06789 uncharacterized protein\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
			}
			]
		},
		{
			"name":"MDP-1",
			"children":[
			{
				"name":"PgNI_01366 uncharacterized protein\tK17619 MDP1; magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]"
			}
			]
		},
		{
			"name":"EYAs"
		},
		{
			"name":"Other HAD phosphatases",
			"children":[
			{
				"name":"PgNI_11937 uncharacterized protein\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
			},
			{
				"name":"PgNI_00337 uncharacterized protein\tK01079 serB; phosphoserine phosphatase [EC:3.1.3.3]"
			},
			{
				"name":"PgNI_03597 uncharacterized protein\tK17623 PUDP; pseudouridine 5'-phosphatase [EC:3.1.3.96]"
			},
			{
				"name":"PgNI_04236 uncharacterized protein\tK15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]"
			},
			{
				"name":"PgNI_07932 uncharacterized protein\tK21830 pchP; phosphoethanolamine\/phosphocholine phosphatase [EC:3.1.3.75]"
			}
			]
		}
		]
	}
	]
}