{
	"name":"piz03110",
	"children":[
	{
		"name":"Heat shock proteins",
		"children":[
		{
			"name":"HSP110"
		},
		{
			"name":"HSP100",
			"children":[
			{
				"name":"LAB08_R39280 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA\tK03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA"
			},
			{
				"name":"LAB08_R52450 clpB; ATP-dependent chaperone ClpB\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			},
			{
				"name":"LAB08_R40450 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
			},
			{
				"name":"LAB08_R03600 hslU; HslU--HslV peptidase ATPase subunit\tK03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU"
			}
			]
		},
		{
			"name":"HSP90",
			"children":[
			{
				"name":"LAB08_R45030 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
			}
			]
		},
		{
			"name":"HSP70 \/ DNAK",
			"children":[
			{
				"name":"LAB08_R06890 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"LAB08_R09230 hscA; Fe-S protein assembly chaperone HscA\tK04044 hscA; molecular chaperone HscA"
			},
			{
				"name":"LAB08_R05360 Hsp70 family protein\tK04046 yegD; hypothetical chaperone protein"
			}
			]
		},
		{
			"name":"HSP60 \/ Chaperonin",
			"children":[
			{
				"name":"LAB08_R49520 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			}
			]
		},
		{
			"name":"HSP47"
		},
		{
			"name":"HSP40 \/ DNAJ",
			"children":[
			{
				"name":"LAB08_R06900 dnaJ; molecular chaperone DnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
			},
			{
				"name":"LAB08_R05370 DnaJ domain-containing protein\tK05516 cbpA; curved DNA-binding protein"
			},
			{
				"name":"LAB08_R55310 TerB family tellurite resistance protein\tK05801 djlA; DnaJ like chaperone protein"
			},
			{
				"name":"LAB08_R09220 hscB; co-chaperone HscB\tK04082 hscB; molecular chaperone HscB"
			}
			]
		},
		{
			"name":"HSP33",
			"children":[
			{
				"name":"LAB08_R02340 hslO; Hsp33 family molecular chaperone HslO\tK04083 hslO; molecular chaperone Hsp33"
			}
			]
		},
		{
			"name":"HSP24",
			"children":[
			{
				"name":"LAB08_R06880 grpE; nucleotide exchange factor GrpE\tK03687 GRPE; molecular chaperone GrpE"
			}
			]
		},
		{
			"name":"HSP20",
			"children":[
			{
				"name":"LAB08_R17870 Hsp20 family protein\tK04080 ibpA; molecular chaperone IbpA"
			}
			]
		},
		{
			"name":"HSP15",
			"children":[
			{
				"name":"LAB08_R02330 RNA-binding protein S4\tK04762 hslR; ribosome-associated heat shock protein Hsp15"
			}
			]
		},
		{
			"name":"HSP10",
			"children":[
			{
				"name":"LAB08_R49530 co-chaperone GroES\tK04078 groES; chaperonin GroES"
			}
			]
		},
		{
			"name":"GimC"
		}
		]
	},
	{
		"name":"Other chaperones and cochaperones",
		"children":[
		{
			"name":"Calnexin \/ calreticulin"
		},
		{
			"name":"DegP \/ HtrA",
			"children":[
			{
				"name":"LAB08_R12820 DegQ family serine endoprotease\tK04771 degP; serine protease Do [EC:3.4.21.107]"
			}
			]
		},
		{
			"name":"AAA proteases",
			"children":[
			{
				"name":"LAB08_R06980 ftsH; ATP-dependent zinc metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"PapD",
			"children":[
			{
				"name":"LAB08_R60330 atpB; F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
			},
			{
				"name":"LAB08_R26920 molecular chaperone\tK07346 fimC; fimbrial chaperone protein"
			}
			]
		},
		{
			"name":"SecB",
			"children":[
			{
				"name":"LAB08_R03010 secB; protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB"
			}
			]
		},
		{
			"name":"Sti1 \/ p60"
		},
		{
			"name":"Cdc37 \/ p50"
		},
		{
			"name":"BAG"
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"LAB08_R14410 LTXXQ domain-containing protein\tK06006 cpxP; periplasmic protein CpxP\/Spy"
			},
			{
				"name":"LAB08_R05580 copper chaperone PCu(A)C\tK09796 pccA; periplasmic copper chaperone A"
			},
			{
				"name":"LAB08_R36940 copper chaperone PCu(A)C\tK09796 pccA; periplasmic copper chaperone A"
			}
			]
		}
		]
	},
	{
		"name":"Intramolecular chaperones",
		"children":[
		{
			"name":"Subtilisin family"
		},
		{
			"name":"Papain family"
		},
		{
			"name":"Other peptidases"
		},
		{
			"name":"Others"
		}
		]
	},
	{
		"name":"Protein folding catalysts",
		"children":[
		{
			"name":"Peptidyl prolyl isomerase",
			"children":[
			{
				"name":"Cyclophilin",
				"children":[
				{
					"name":"LAB08_R46530 peptidylprolyl isomerase A\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R39640 peptidyl-prolyl cis-trans isomerase\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R40410 SurA N-terminal domain-containing protein\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"FKBP",
				"children":[
				{
					"name":"LAB08_R44520 FKBP-type peptidyl-prolyl cis-trans isomerase\tK03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R52750 FKBP-type peptidyl-prolyl cis-trans isomerase\tK03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R58510 FKBP-type peptidyl-prolyl cis-trans isomerase\tK03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R52610 fkpB; FKBP-type peptidyl-prolyl cis-trans isomerase\tK03774 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase SlpA [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R08050 peptidylprolyl isomerase\tK03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"Parvulin",
				"children":[
				{
					"name":"LAB08_R25560 peptidylprolyl isomerase\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R25670 peptidylprolyl isomerase\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]"
				},
				{
					"name":"LAB08_R55350 surA; peptidylprolyl isomerase SurA\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]"
				}
				]
			}
			]
		},
		{
			"name":"Protein disulfide isomerase",
			"children":[
			{
				"name":"LAB08_R58370 trxA; thioredoxin TrxA\tK03671 TXN; thioredoxin"
			},
			{
				"name":"LAB08_R04040 trxC; thioredoxin TrxC\tK03672 trxC; thioredoxin 2 [EC:1.8.1.8]"
			},
			{
				"name":"LAB08_R54260 trxA; thioredoxin\tK05838 ybbN; putative thioredoxin"
			},
			{
				"name":"LAB08_R03000 grxC; glutaredoxin 3\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"LAB08_R21210 grxC; glutaredoxin 3\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"LAB08_R49750 grxD; Grx4 family monothiol glutaredoxin\tK07390 grxD; monothiol glutaredoxin"
			},
			{
				"name":"LAB08_R00500 thiol:disulfide interchange protein DsbA\/DsbL\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]"
			},
			{
				"name":"LAB08_R08530 disulfide bond formation protein B\tK03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9]"
			},
			{
				"name":"LAB08_R58530 disulfide bond formation protein B\tK03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9]"
			},
			{
				"name":"LAB08_R49940 DsbC family protein\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"LAB08_R05800 protein-disulfide reductase DsbD\tK04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16]"
			},
			{
				"name":"LAB08_R42810 dsbD; protein-disulfide reductase DsbD\tK04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16]"
			},
			{
				"name":"LAB08_R45630 DsbE family thiol:disulfide interchange protein\tK02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE"
			},
			{
				"name":"LAB08_R42830 dsbG; thiol:disulfide interchange protein DsbG\tK03805 dsbG; thiol:disulfide interchange protein DsbG"
			}
			]
		}
		]
	}
	]
}
