{
	"name":"plf01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"PANA5342_3862 murA; UDP-N-acetylglucosamine1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"PANA5342_4221 murB; UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"PANA5342_3590 murC; L-alanine adding enzyme, UDP-N-acetyl-muramate:alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"PANA5342_3593 murD; UDP-N-acetylmuramoylalanine\/D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"PANA5342_3596 murE; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"PANA5342_0611 ddlA; D-alanine\/D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			},
			{
				"name":"PANA5342_3589 ddlB; D-alanine-D-alanine ligase B DdlB\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"PANA5342_2051 dadB; alanine racemase 2, catabolic\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"PANA5342_0204 murI; Glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"PANA5342_2678 ycgQ; muramoyltetrapeptide carboxypeptidase A\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"PANA5342_3594 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"PANA5342_3591 murG; UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"PANA5342_0674 bacA; undecaprenyl pyrophosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"PANA5342_2975 ybjG; undecaprenyl-diphosphatase\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"PANA5342_2768 mviN; virulence factor MviN\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"PANA5342_0371 mrcA; penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"PANA5342_3533 mrcB; penicillin-binding protein 1b\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"PANA5342_1181 pbpC; penicillin-binding protein 1C PbpC\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"PANA5342_0769 mrdA1; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"PANA5342_3165 mrdA3; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"PANA5342_3597 ftsI1; division specific transpeptidase, penicillin-binding protein 3\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			},
			{
				"name":"PANA5342_3821 ftsI3; peptidoglycan synthetase FtsI\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"PANA5342_1633 dacD; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"PANA5342_2976 ddaC; D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"PANA5342_3168 dacA; penicillin-binding protein 5 precursor DacA\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"PANA5342_3853 dacB; D-alanyl-D-alaninecarboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"PANA5342_1262 ampH; penicillin-binding protein AmpH\tK18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"PANA5342_3044 pbpG; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1\tK07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"PANA5342_3880 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"PANA5342_3592 ftsW; cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"PANA5342_3166 mrdB; rod shape-determining protein\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase",
			"children":[
			{
				"name":"PANA5342_2492 ycfS; ErfK\/YbiS\/YcfS\/YnhG family protein YcfS\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"PANA5342_3051 ybiS; ErfK\/YbiS\/YcfS\/YnhG family protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"PANA5342_2912 ycbB; ErfK\/YbiS\/YcfS\/YnhG family protein\tK21470 ldtD; L,D-transpeptidase"
			},
			{
				"name":"PANA5342_3428 yafK; ErfK\/YbiS\/YcfS\/YnhG family protein\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"PANA5342_0285 ddpX; D-alanyl-D-alanine dipeptidase\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
			}
			]
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"PANA5342_1367 mepA; penicillin-insensitive murein endopeptidase\tK07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]"
			},
			{
				"name":"PANA5342_2481 ydhO; NLP\/P60 protein\tK19303 mepH; murein DD-endopeptidase [EC:3.4.-.-]"
			},
			{
				"name":"PANA5342_1508 spr; NLP\/P60 outer membrane lipoprotein\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
			},
			{
				"name":"PANA5342_1968 yebA; peptidase M23\tK19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Sortase"
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"PANA5342_3667 slt; soluble lytic murein transglycosylase precursor Slt\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_0931 mltA; membrane-bound lytic murein transglycosylase A\tK08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_0997 mltB; lytic murein transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_0837 mltC; membrane-bound lytic murein transglycosylase C\tK08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_3481 mltD; membrane-bound lytic murein transglycosylase D\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_2677 mltE; membrane-bound lytic murein transglycosylase E\tK08308 mltE; peptidoglycan lytic transglycosylase E [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_1159 yfhD; lytic transglycosylase catalytic\tK18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_2738 yceG; aminodeoxychorismate lyase\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			},
			{
				"name":"PANA5342_3167 rlpA; rare lipoprotein A precursor RlpA\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"PANA5342_0505 amiB; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"PANA5342_0929 amiC; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"PANA5342_1271 amiA; hypothetical protein\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"PANA5342_2401 amiD; N-acetylmuramoyl-L-alanine amidase AmiD\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"PANA5342_2953 ybjR; N-acetylmuramoyl-L-alanine amidase AmiD\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"PANA5342_3574 ampD; N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD\tK03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein",
			"children":[
			{
				"name":"PANA5342_2491 lpp; major outer membrane lipoprotein\tK06078 lpp; murein lipoprotein"
			}
			]
		}
		]
	}
	]
}