{
	"name":"ppa03012",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Initiation factors",
			"children":[
			{
				"name":"eIF-1",
				"children":[
				{
					"name":"PAS_chr2-1_0741 Translation initiation factor eIF1A\tK03236 EIF1A; translation initiation factor 1A"
				},
				{
					"name":"PAS_chr4_0880 Translation initiation factor eIF1\tK03113 EIF1; translation initiation factor 1"
				}
				]
			},
			{
				"name":"eIF-2",
				"children":[
				{
					"name":"PAS_chr3_0077 Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start\tK03237 EIF2S1; translation initiation factor 2 subunit 1"
				},
				{
					"name":"PAS_chr1-4_0135 Beta subunit of the translation initiation factor eIF2\tK03238 EIF2S2; translation initiation factor 2 subunit 2"
				},
				{
					"name":"PAS_chr3_0839 Gamma subunit of the translation initiation factor eIF2\tK03242 EIF2S3; translation initiation factor 2 subunit 3"
				}
				]
			},
			{
				"name":"eIF-2A",
				"children":[
				{
					"name":"PAS_chr2-2_0058 Eukaryotic initiation factor (eIF) 2A\tK15026 EIF2A; translation initiation factor 2A"
				}
				]
			},
			{
				"name":"eIF-2B",
				"children":[
				{
					"name":"PAS_chr4_0032 Alpha subunit of the translation initiation factor eIF2B\tK03239 EIF2B1; translation initiation factor eIF-2B subunit alpha"
				},
				{
					"name":"PAS_chr3_0564 Beta subunit of the translation initiation factor eIF2B\tK03754 EIF2B2; translation initiation factor eIF-2B subunit beta"
				},
				{
					"name":"PAS_chr4_0386 Gamma subunit of the translation initiation factor eIF2B\tK03241 EIF2B3; translation initiation factor eIF-2B subunit gamma"
				},
				{
					"name":"PAS_chr2-2_0275 Delta subunit of the translation initiation factor eIF2B\tK03680 EIF2B4; translation initiation factor eIF-2B subunit delta"
				},
				{
					"name":"PAS_chr3_0391 Catalytic epsilon subunit of the translation initiation factor eIF2B\tK03240 EIF2B5; translation initiation factor eIF-2B subunit epsilon"
				}
				]
			},
			{
				"name":"eIF-2D",
				"children":[
				{
					"name":"PAS_chr3_0476 Protein of unknown function that associates with ribosomes\tK15027 EIF2D; translation initiation factor 2D"
				}
				]
			},
			{
				"name":"eIF-5",
				"children":[
				{
					"name":"PAS_chr4_0771 Translation initiation factor eIF-5\tK03262 EIF5; translation initiation factor 5"
				},
				{
					"name":"PAS_chr3_1048 Translation initiation factor eIF-5A, promotes formation of the first peptide bond\tK03263 EIF5A; translation initiation factor 5A"
				},
				{
					"name":"PAS_chr1-1_0254 GTPase\tK03243 EIF5B; translation initiation factor 5B"
				}
				]
			},
			{
				"name":"eIF-6",
				"children":[
				{
					"name":"PAS_chr1-3_0101 Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6\tK03264 EIF6; translation initiation factor 6"
				}
				]
			},
			{
				"name":"eIF-3",
				"children":[
				{
					"name":"PAS_chr3_0340 Subunit of the core complex of translation initiation factor 3(eIF3)\tK03254 EIF3A; translation initiation factor 3 subunit A"
				},
				{
					"name":"PAS_chr3_0701 Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation\tK03253 EIF3B; translation initiation factor 3 subunit B"
				},
				{
					"name":"PAS_chr3_0774 Subunit of the eukaryotic translation initiation factor 3 (eIF3)\tK03252 EIF3C; translation initiation factor 3 subunit C"
				},
				{
					"name":"PAS_chr3_0747 hypothetical protein\tK03251 EIF3D; translation initiation factor 3 subunit D"
				},
				{
					"name":"PAS_chr1-4_0147 eukaryotic translation initiation factor 3 subunit\tK03250 EIF3E; translation initiation factor 3 subunit E"
				},
				{
					"name":"PAS_chr1-4_0289 hypothetical protein\tK03249 EIF3F; translation initiation factor 3 subunit F"
				},
				{
					"name":"PAS_chr4_0434 Subunit of the core complex of translation initiation factor 3(eIF3)\tK03248 EIF3G; translation initiation factor 3 subunit G"
				},
				{
					"name":"PAS_chr3_0948 hypothetical protein\tK03247 EIF3H; translation initiation factor 3 subunit H"
				},
				{
					"name":"PAS_chr1-3_0281 Subunit of the core complex of translation initiation factor (eIF3)\tK03246 EIF3I; translation initiation factor 3 subunit I"
				},
				{
					"name":"PAS_chr3_1022 Dual function protein\tK03245 EIF3J; translation initiation factor 3 subunit J"
				},
				{
					"name":"PAS_chr2-2_0120 hypothetical protein\tK15030 EIF3M; translation initiation factor 3 subunit M"
				}
				]
			},
			{
				"name":"eIF-4",
				"children":[
				{
					"name":"PAS_chr3_0595 Translation initiation factor eIF4A, identical to Tif1p\tK03257 EIF4A; translation initiation factor 4A"
				},
				{
					"name":"PAS_chr1-4_0461 Nucleolar protein required for maturation of 18S rRNA\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
				},
				{
					"name":"PAS_chr3_1054 Translation initiation factor eIF-4B, has RNA annealing activity\tK03258 EIF4B; translation initiation factor 4B"
				},
				{
					"name":"PAS_chr3_0972 Cytoplasmic mRNA cap binding protein\tK03259 EIF4E; translation initiation factor 4E"
				},
				{
					"name":"PAS_chr1-1_0053 Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F)\tK03260 EIF4G; translation initiation factor 4G"
				},
				{
					"name":"PAS_chr1-3_0179 hypothetical protein\tK03261 CAF20; cap-associated protein CAF20"
				}
				]
			},
			{
				"name":"MTIFs",
				"children":[
				{
					"name":"PAS_chr2-1_0244 Mitochondrial translation initiation factor 2\tK02519 infB; translation initiation factor IF-2"
				}
				]
			},
			{
				"name":"Initiation associated factors",
				"children":[
				{
					"name":"PAS_chr3_1044 Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3"
				},
				{
					"name":"PAS_chr3_0925 eIF3 component of unknown function\tK03255 TIF31; protein TIF31"
				},
				{
					"name":"PAS_chr2-1_0603 Putative helicase with limited sequence similarity to human Rb protein\tK13026 DHX57; ATP-dependent RNA helicase DHX57 [EC:5.6.2.6]"
				},
				{
					"name":"PAS_chr3_0572 Protein involved in nutritional control of the cell cycle\tK28153 CDC123; translation initiation factor eIF2 assembly protein"
				},
				{
					"name":"PAS_chr3_0850 Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p)\tK16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr4_0327 Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p\tK28917 GCN1; eIF-2-alpha kinase activator"
				},
				{
					"name":"PAS_chr2-1_0618 hypothetical protein\tK15908 EAP1; protein EAP1"
				}
				]
			}
			]
		},
		{
			"name":"Elongation factors",
			"children":[
			{
				"name":"PAS_FragB_0052 Translational elongation factor EF-1 alpha\tK03231 EEF1A; elongation factor 1-alpha"
			},
			{
				"name":"PAS_chr2-1_0376 Putative GTPase, member of the Obg family\tK03232 EEF1B; elongation factor 1-beta"
			},
			{
				"name":"PAS_chr1-4_0226 hypothetical protein\tK03233 EEF1G; elongation factor 1-gamma"
			},
			{
				"name":"PAS_chr3_1071 Translation elongation factor EF-1 gamma\tK03233 EEF1G; elongation factor 1-gamma"
			},
			{
				"name":"PAS_chr4_0102 elongation factor 1 gamma domain-containing protein\tK03233 EEF1G; elongation factor 1-gamma"
			},
			{
				"name":"PAS_chr2-1_0812 hypothetical protein\tK03234 EEF2; elongation factor 2"
			},
			{
				"name":"PAS_chr3_0728 ATP binding cassette family member\tK03235 EF3; elongation factor 3"
			},
			{
				"name":"PAS_chr4_0038 Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes\tK03235 EF3; elongation factor 3"
			},
			{
				"name":"PAS_chr3_0562 Mitochondrial translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"PAS_chr2-2_0409 Mitochondrial elongation factor involved in translational elongation\tK02355 fusA; elongation factor G"
			},
			{
				"name":"PAS_chr4_0033 Mitochondrial elongation factor involved in translational elongation\tK02355 fusA; elongation factor G"
			},
			{
				"name":"Elongation associated factors",
				"children":[
				{
					"name":"PAS_chr4_0072 Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide\tK07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]"
				},
				{
					"name":"PAS_chr2-1_0594 Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide\tK17866 DPH2; diphthamide biosynthesis protein 2"
				},
				{
					"name":"PAS_chr1-1_0438 Zn-ribbon protein\tK15455 DPH3; diphthamide biosynthesis protein 3"
				},
				{
					"name":"PAS_chr2-1_0803 Protein of unknown function, contains a J-domain\tK17867 DPH4; diphthamide biosynthesis protein 4"
				},
				{
					"name":"PAS_chr2-1_0577 Methyltransferase required for synthesis of diphthamide\tK00586 DPH5; diphthine methyl ester synthase [EC:2.1.1.314]"
				},
				{
					"name":"PAS_chr4_0132 Putative protein of unknown function\tK06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]"
				},
				{
					"name":"PAS_chr2-1_0734 Putative protein of unknown function\tK17868 DPH7; diphthine methyl ester acylhydrolase [EC:3.1.1.97]"
				},
				{
					"name":"PAS_chr1-4_0602 N(6)-adenine-specific DNA methyltransferase\tK22855 EEF1AKMT1; EEF1A lysine methyltransferase 1 [EC:2.1.1.-]"
				},
				{
					"name":"PAS_chr4_0615 Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family\tK22856 EEF1AKMT2; EEF1A lysine methyltransferase 2 [EC:2.1.1.-]"
				},
				{
					"name":"PAS_chr3_1002 Putative nicotinamide N-methyltransferase\tK17878 NNT1; EEF1A N-terminal glycine\/lysine methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"PAS_chr3_0558 Putative protein of unknown function\tK22696 EEF2KMT; protein-lysine N-methyltransferase EEF2KMT [EC:2.1.1.-]"
				},
				{
					"name":"PAS_chr1-1_0253 Member of the DRG family of GTP-binding proteins\tK06944 DRG1; developmentally-regulated GTP-binding protein 1 [EC:3.6.5.-]"
				},
				{
					"name":"PAS_chr3_1123 Protein with similarity to mammalian developmentally regulated GTP-binding protein\tK27705 DRG2; developmentally-regulated GTP-binding protein 2 [EC:3.6.5.-]"
				},
				{
					"name":"PAS_chr4_0217 Protein of unknown function that associates with ribosomes\tK27706 ZC3H15; zinc finger CCCH domain-containing protein 15"
				}
				]
			}
			]
		},
		{
			"name":"Release factors",
			"children":[
			{
				"name":"PAS_chr4_0727 Polypeptide release factor involved in translation termination\tK03265 ETF1; peptide chain release factor subunit 1"
			},
			{
				"name":"PAS_chr3_0398 Translation termination factor eRF3\tK03267 ERF3; peptide chain release factor subunit 3"
			},
			{
				"name":"PAS_chr2-1_0503 hypothetical protein\tK15033 MRPL58; peptidyl-tRNA hydrolase ICT1 (large subunit ribosomal protein L58) [EC:3.1.1.29]"
			},
			{
				"name":"PAS_chr3_1249 hypothetical protein\tK02835 prfA; peptide chain release factor 1"
			},
			{
				"name":"PAS_chr4_0253 Mitochondrial ribosome recycling factor\tK02838 frr; ribosome recycling factor"
			},
			{
				"name":"PAS_chr2-1_0179 S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family\tK19589 N6AMT1; release factor glutamine methyltransferase [EC:2.1.1.297]"
			},
			{
				"name":"PAS_chr1-4_0374 Subunit of an adoMet-dependent tRNA methyltransferase (MTase) complex (Trm11p-Trm112p)\tK15448 TRM112; multifunctional methyltransferase subunit TRM112"
			},
			{
				"name":"PAS_chr2-2_0138 One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]"
			},
			{
				"name":"PAS_chr2-2_0218 One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases\tK04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]"
			},
			{
				"name":"Termination  associated factors",
				"children":[
				{
					"name":"PAS_chr4_0243 hypothetical protein\tK24029 OGFOD1; prolyl 3-hydroxylase \/prolyl 3,4-dihydroxylase [EC:1.14.11.-]"
				},
				{
					"name":"PAS_chr1-3_0079 Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae\tK29109 ETT1; enhancer of translation termination 1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Initiation factors",
			"children":[
			{
				"name":"PAS_chr2-1_0244 Mitochondrial translation initiation factor 2\tK02519 infB; translation initiation factor IF-2"
			}
			]
		},
		{
			"name":"Elongation factors",
			"children":[
			{
				"name":"PAS_chr3_0562 Mitochondrial translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"PAS_chr2-2_0409 Mitochondrial elongation factor involved in translational elongation\tK02355 fusA; elongation factor G"
			},
			{
				"name":"PAS_chr4_0033 Mitochondrial elongation factor involved in translational elongation\tK02355 fusA; elongation factor G"
			}
			]
		},
		{
			"name":"Release factors",
			"children":[
			{
				"name":"PAS_chr3_1249 hypothetical protein\tK02835 prfA; peptide chain release factor 1"
			},
			{
				"name":"PAS_chr4_0253 Mitochondrial ribosome recycling factor\tK02838 frr; ribosome recycling factor"
			},
			{
				"name":"PAS_chr2-2_0138 One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]"
			},
			{
				"name":"PAS_chr2-2_0218 One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases\tK04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]"
			}
			]
		}
		]
	}
	]
}
