{
	"name":"ppa04131",
	"children":[
	{
		"name":"Exocytosis",
		"children":[
		{
			"name":"Calcium ion-dependent exocytosis",
			"children":[
			{
				"name":"Synaptotagmins"
			},
			{
				"name":"Septins",
				"children":[
				{
					"name":"PAS_chr4_0548 Component of the septin ring of the mother-bud neck that is required for cytokinesis\tK16944 SEPT7; septin 7"
				}
				]
			},
			{
				"name":"DOC-2 proteins"
			},
			{
				"name":"Acrosomal exocytosis proteins",
				"children":[
				{
					"name":"PAS_chr1-4_0069 Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1)\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipases",
				"children":[
				{
					"name":"PAS_chr4_0700 Phospholipase C\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				},
				{
					"name":"PAS_chr3_0646 Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				}
				]
			},
			{
				"name":"Kinases and associated proteins",
				"children":[
				{
					"name":"PAS_chr1-1_0457 Phosphatidylinositol-4-phosphate 5-kinase\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"PAS_c131_0004 hypothetical protein\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr1-1_0057 Putative protein serine\/threonine kinase expressed at the end of meiosis\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr2-2_0059 Nucleoside diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"PAS_chr3_0347 Serine\/threonine protein kinase involved in regulation of exocytosis\tK19852 KIN1_2; serine\/threonine protein kinase KIN1\/2 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr1-1_0170 N-myristoylated calcium-binding protein that may have a role in intracellular signaling\tK19932 NCS1; neuronal calcium sensor"
				}
				]
			}
			]
		},
		{
			"name":"Small GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"PAS_chr3_0143 Secretory vesicle-associated Rab GTPase essential for exocytosis\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0758 Calmodulin\tK02183 CALM; calmodulin"
				},
				{
					"name":"PAS_chr2-2_0435 hypothetical protein\tK02183 CALM; calmodulin"
				},
				{
					"name":"PAS_chr2-2_0014 Guanyl-nucleotide exchange factor for the small G-protein Sec4p\tK19940 SEC2; Rab guanine nucleotide exchange factor SEC2"
				},
				{
					"name":"PAS_chr4_0134 Sm-like protein involved in docking and fusion of exocytic vesicles\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"PAS_chr1-4_0066 Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p\tK08518 STXBP5; syntaxin-binding protein 5"
				},
				{
					"name":"PAS_FragB_0076 hypothetical protein\tK19952 RABIF; guanine nucleotide exchange factor"
				},
				{
					"name":"PAS_chr2-1_0074 GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its acti\tK19953 GRTP1; TBC1 domain family member 6"
				},
				{
					"name":"PAS_chr3_0801 Cytoplasmic GTPase-activating protein for Ypt\/Rab transport GTPases Ypt6p, Ypt31p and Sec4p\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"PAS_chr2-2_0186 Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1)\tK13342 PEX5; peroxin-5"
				},
				{
					"name":"PAS_chr3_0586 Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"PAS_chr4_0741 Alpha subunit of Type II geranylgeranyltransferase\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"PAS_chr3_0764 Beta subunit of Type II geranylgeranyltransferase\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"PAS_chr2-1_0345 Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"Rho GTPases",
				"children":[
				{
					"name":"PAS_chr2-1_0112 Small rho-like GTPase, essential for establishment and maintenance of cell polarity\tK04393 CDC42; cell division control protein 42"
				},
				{
					"name":"PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				}
				]
			},
			{
				"name":"Other small GTPases and associated proteins"
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Exocyst complex",
				"children":[
				{
					"name":"PAS_chr1-4_0550 hypothetical protein\tK19983 EXOC1; exocyst complex component 1"
				},
				{
					"name":"PAS_chr3_1229 hypothetical protein\tK17637 EXOC2; exocyst complex component 2"
				},
				{
					"name":"PAS_chr1-4_0452 Essential 88kDa subunit of the exocyst complex\tK06110 EXOC3; exocyst complex component 3"
				},
				{
					"name":"PAS_chr2-1_0039 Essential 121kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p\tK06111 EXOC4; exocyst complex component 4"
				},
				{
					"name":"PAS_chr1-4_0334 Essential 100kDa subunit of the exocyst complex\tK19984 EXOC5; exocyst complex component 5"
				},
				{
					"name":"PAS_chr2-1_0297 Essential 113kDa subunit of the exocyst complex\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"PAS_chr4_0695 Essential 70kDa subunit of the exocyst complex\tK07195 EXOC7; exocyst complex component 7"
				},
				{
					"name":"PAS_chr4_0078 Essential protein with dual roles in spliceosome assembly and exocytosis\tK19986 EXOC8; exocyst complex component 8"
				}
				]
			},
			{
				"name":"Exocyst complex assembly proteins",
				"children":[
				{
					"name":"PAS_chr4_0299 hypothetical protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
				},
				{
					"name":"PAS_chr4_0115 Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments\tK17945 TPM1_2; tropomyosin, fungi type"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Exomer complex",
				"children":[
				{
					"name":"PAS_chr4_0675 Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p\tK19877 CHS5; chitin biosynthesis protein CHS5"
				},
				{
					"name":"PAS_chr4_0542 Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p)\tK19880 CHS6; Chs5-Arf1p-binding protein CHS6\/BCH2"
				},
				{
					"name":"PAS_chr2-1_0141 Member of the ChAPs family (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms th\tK19881 BUD7; Chs5-Arf1p-binding protein BUD7\/BCH1"
				}
				]
			},
			{
				"name":"ER-PM contacts associated proteins",
				"children":[
				{
					"name":"PAS_FragB_0002 Protein CSF1\tK24964 BLTP1; Bridge-like lipid transfer protein family member 1"
				},
				{
					"name":"PAS_chr1-1_0120 Lipid-binding protein, localized to the bud via specific mRNA transport\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"PAS_chr3_0488 Bud-specific protein with a potential role in membrane trafficking\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"PAS_chr2-2_0463 hypothetical protein\tK29085 SCS2_22; vesicle-associated membrane protein-associated protein"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr3_0529 hypothetical protein\tK19992 MSO1; protein MSO1"
				},
				{
					"name":"PAS_chr2-1_0830 hypothetical protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"PAS_chr2-2_0077 Putative phosphatidylinositol transfer protein (PITP)\tK19996 SFH5; phosphatidylinositol transfer protein SFH5"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"SNARE",
		"children":[
		{
			"name":"Syntaxin (Qa)",
			"children":[
			{
				"name":"Stx-PM",
				"children":[
				{
					"name":"PAS_chr1-4_0294 Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane\tK08486 STX1B_2_3; syntaxin 1B\/2\/3"
				}
				]
			},
			{
				"name":"Stx-Endo",
				"children":[
				{
					"name":"PAS_chr2-2_0350 Target membrane receptor (t-SNARE)\tK21155 VAM3; syntaxin VAM3"
				}
				]
			},
			{
				"name":"Stx-TGN \/ EE",
				"children":[
				{
					"name":"PAS_chr3_1238 hypothetical protein\tK08489 STX16; syntaxin 16"
				}
				]
			},
			{
				"name":"Stx-cisGolgi",
				"children":[
				{
					"name":"PAS_chr1-4_0024 cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex\tK08490 STX5; syntaxin 5"
				}
				]
			},
			{
				"name":"Stx-sER"
			},
			{
				"name":"Stx-rER",
				"children":[
				{
					"name":"PAS_chr3_0989 t-SNARE required for ER membrane fusion and vesicular traffic\tK08492 STX18; syntaxin 18"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[N] (Qb)",
			"children":[
			{
				"name":"Vti1",
				"children":[
				{
					"name":"PAS_chr3_1085 Protein involved in cis-Golgi membrane traffic\tK08493 VTI1; vesicle transport through interaction with t-SNAREs 1"
				}
				]
			},
			{
				"name":"NPSN"
			},
			{
				"name":"Gos1 (Gos28)",
				"children":[
				{
					"name":"PAS_chr2-1_0161 v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28\/GS28\tK08495 GOSR1; golgi SNAP receptor complex member 1"
				}
				]
			},
			{
				"name":"Bos1 \/ Membrin",
				"children":[
				{
					"name":"PAS_chr2-2_0453 hypothetical protein\tK08496 GOSR2; golgi SNAP receptor complex member 2"
				}
				]
			},
			{
				"name":"Sec20",
				"children":[
				{
					"name":"PAS_chr1-4_0462 Membrane glycoprotein V-SNARE\tK08497 SEC20; protein transport protein SEC20"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[C] (Qc)",
			"children":[
			{
				"name":"STX6",
				"children":[
				{
					"name":"PAS_chr3_0048 Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived\tK08499 TLG1; member of the syntaxin family of t-SNAREs"
				}
				]
			},
			{
				"name":"STX8",
				"children":[
				{
					"name":"PAS_chr1-1_0246 hypothetical protein\tK08501 STX8; syntaxin 8"
				},
				{
					"name":"PAS_chr1-4_0500 hypothetical protein\tK08502 VAM7; regulator of vacuolar morphogenesis"
				}
				]
			},
			{
				"name":"STX10"
			},
			{
				"name":"Bet1",
				"children":[
				{
					"name":"PAS_chr1-3_0161 Type II membrane protein required for vesicular transport\tK08504 BET1; blocked early in transport 1"
				}
				]
			},
			{
				"name":"Sft1"
			},
			{
				"name":"Syp7"
			},
			{
				"name":"Use1",
				"children":[
				{
					"name":"PAS_chr1-1_0481 hypothetical protein\tK08507 USE1; unconventional SNARE in the endoplasmic reticulum protein 1"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25 (Qb,c)",
			"children":[
			{
				"name":"SNAP-23"
			},
			{
				"name":"SNAP-25",
				"children":[
				{
					"name":"PAS_chr2-2_0132 t-SNARE protein important for fusion of secretory vesicles with the plasma membrane\tK19950 SEC9; protein transport protein SEC9"
				}
				]
			},
			{
				"name":"SNAP-29"
			},
			{
				"name":"SNAP-47"
			}
			]
		},
		{
			"name":"VAMP, Ykt6, Sec22 (R)",
			"children":[
			{
				"name":"VAMP",
				"children":[
				{
					"name":"PAS_FragB_0011 Synaptobrevin homolog 2\tK08513 VAMP4; vesicle-associated membrane protein 4"
				},
				{
					"name":"PAS_chr2-1_0099 hypothetical protein\tK08515 VAMP7; vesicle-associated membrane protein 7"
				}
				]
			},
			{
				"name":"Ykt6",
				"children":[
				{
					"name":"PAS_FragB_0006 Synaptobrevin homolog YKT6\tK08516 YKT6; synaptobrevin homolog YKT6"
				}
				]
			},
			{
				"name":"Sec22",
				"children":[
				{
					"name":"PAS_chr3_0274 R-SNARE protein\tK08517 SEC22; vesicle transport protein SEC22"
				}
				]
			},
			{
				"name":"Tomosyn",
				"children":[
				{
					"name":"PAS_chr1-4_0066 Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p\tK08518 STXBP5; syntaxin-binding protein 5"
				}
				]
			},
			{
				"name":"Putative SNAREs"
			}
			]
		},
		{
			"name":"SNARE associated proteins",
			"children":[
			{
				"name":"Syntaxin-binding proteins",
				"children":[
				{
					"name":"PAS_chr4_0134 Sm-like protein involved in docking and fusion of exocytic vesicles\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"PAS_chr4_0251 Hydrophilic protein, involved in vesicle trafficking between the ER and Golgi\tK19998 SCFD1; sec1 family domain-containing protein 1"
				}
				]
			},
			{
				"name":"Palmitoyltransferases",
				"children":[
				{
					"name":"PAS_chr1-4_0126 Palmitoyltransferase for Vac8p, required for vacuolar membrane fusion\tK20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2\/15\/20 [EC:2.3.1.225]"
				},
				{
					"name":"PAS_chr2-1_0056 Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs\tK20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]"
				},
				{
					"name":"PAS_chr2-1_0829 hypothetical protein\tK20032 ZDHHC13_17; palmitoyltransferase ZDHHC13\/17 [EC:2.3.1.225]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr3_0342 ATPase required for the release of Sec17p\tK06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]"
				},
				{
					"name":"PAS_chr2-1_0644 Peripheral membrane protein required for vesicular transport between ER and Golgi\tK15296 NAPA; alpha-soluble NSF attachment protein"
				},
				{
					"name":"PAS_chr2-1_0389 Sorting nexin\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"PAS_chr2-2_0030 Sorting nexin family member\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"PAS_chr3_1139 Sorting nexin\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"PAS_FragD_0026 ATPase in ER, nuclear membrane and cytosol with homology to mammalian P97\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"PAS_chr2-1_0159 UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and\tK14012 NSFL1C; UBX domain-containing protein 1"
				},
				{
					"name":"PAS_FragB_0007 Protein VTS1\tK27407 VTS1; RNA-binding protein VTS1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endocytosis",
		"children":[
		{
			"name":"Clathrin-mediated endocytosis",
			"children":[
			{
				"name":"Clathrin",
				"children":[
				{
					"name":"PAS_chr1-4_0546 Clathrin heavy chain, subunit of the major coat protein\tK04646 CLTC; clathrin heavy chain"
				}
				]
			},
			{
				"name":"Dynamin",
				"children":[
				{
					"name":"PAS_chr3_0751 Dynamin-related GTPase\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			},
			{
				"name":"AP-2 complex",
				"children":[
				{
					"name":"PAS_chr2-1_0496 Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2)\tK11824 AP2A; AP-2 complex subunit alpha"
				},
				{
					"name":"PAS_chr3_0079 Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2)\tK11825 AP2B1; AP-2 complex subunit beta-1"
				},
				{
					"name":"PAS_chr2-2_0175 Mu2-like subunit of the clathrin associated protein complex (AP-2)\tK11826 AP2M1; AP-2 complex subunit mu-1"
				},
				{
					"name":"PAS_chr3_1047 Small subunit of the clathrin-associated adaptor complex AP-2\tK11827 AP2S1; AP-2 complex subunit sigma-1"
				}
				]
			},
			{
				"name":"Other core components",
				"children":[
				{
					"name":"PAS_chr3_0865 Protein with a potential role in actin cytoskeletal organization\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"PAS_FragB_0073 hypothetical protein\tK12471 EPN; epsin"
				},
				{
					"name":"PAS_chr1-4_0244 Epsin-like protein involved in endocytosis and actin patch assembly\tK12471 EPN; epsin"
				},
				{
					"name":"PAS_chr4_0763 Protein containing an N-terminal epsin-like domain\tK12471 EPN; epsin"
				},
				{
					"name":"PAS_chr2-1_0651 Key endocytic protein involved in a network of interactions with other endocytic proteins\tK12472 EPS15; epidermal growth factor receptor substrate 15"
				},
				{
					"name":"PAS_chr2-2_0405 Protein involved in clathrin cage assembly\tK20044 PICALM; phosphatidylinositol-binding clathrin assembly protein"
				},
				{
					"name":"PAS_chr2-1_0116 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p)\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr3_0498 Actin-associated protein\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr3_0983 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p)\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr2-1_0366 Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"PAS_chr3_0694 Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"PAS_chr4_0920 hypothetical protein\tK20048 END3; actin cytoskeleton-regulatory complex protein END3"
				},
				{
					"name":"PAS_chr3_0230 ATPase involved in protein folding and the response to stress\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"PAS_chr3_0731 Cytoplasmic ATPase that is a ribosome-associated molecular chaperone\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"PAS_chr4_0552 ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				}
				]
			},
			{
				"name":"Low-density lipoprotein receptor (LDLR) family proteins"
			},
			{
				"name":"LDLR adaptor proteins",
				"children":[
				{
					"name":"PAS_chr1-1_0457 Phosphatidylinositol-4-phosphate 5-kinase\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				}
				]
			},
			{
				"name":"GPCR adaptor proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0255 Protein of unknown function involved in maintenance of proper telomere length\tK20059 LDB19; arrestin-related trafficking adapter 1"
				},
				{
					"name":"PAS_chr1-3_0216 hypothetical protein\tK20060 ECM21; arrestin-related trafficking adapter 2\/8"
				},
				{
					"name":"PAS_chr4_0694 Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p\tK20061 ALY1_2; arrestin-related trafficking adapter 3\/6"
				},
				{
					"name":"PAS_chr3_0930 Membrane protein\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"PAS_chr3_1017 Putative protein of unknown function\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"PAS_chr4_0184 hypothetical protein\tK20063 RIM8; arrestin-related trafficking adapter 9"
				}
				]
			},
			{
				"name":"Receptor tyrosine kinase (RTK) adaptor proteins"
			},
			{
				"name":"Inositol 5-phosphatases",
				"children":[
				{
					"name":"PAS_chr2-1_0178 Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				},
				{
					"name":"PAS_chr2-1_0424 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sa\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"PAS_chr2-1_0460 Protein serine\/threonine kinase\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr2-1_0028 Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase\tK17541 SCYL2; SCY1-like protein 2"
				}
				]
			},
			{
				"name":"Ubiquitin E3 ligases",
				"children":[
				{
					"name":"PAS_chr2-1_0354 Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr4_0879 Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization\tK20040 HIP1R; huntingtin-interacting protein 1-related protein"
				},
				{
					"name":"PAS_chr2-1_0322 Calnexin\tK08054 CANX; calnexin"
				}
				]
			}
			]
		},
		{
			"name":"Lipid raft mediated endocytosis",
			"children":[
			{
				"name":"Caveolin-mediated endocytosis",
				"children":[
				{
					"name":"PAS_chr3_0751 Dynamin-related GTPase\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				},
				{
					"name":"PAS_chr2-1_0124 Elongation factor 2 (EF-2), also encoded by EFT1\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
				}
				]
			},
			{
				"name":"Flotillin-dependent endocytosis"
			},
			{
				"name":"GRAF1-dependent endocytosis",
				"children":[
				{
					"name":"PAS_chr2-1_0112 Small rho-like GTPase, essential for establishment and maintenance of cell polarity\tK04393 CDC42; cell division control protein 42"
				},
				{
					"name":"PAS_chr2-2_0087 ADP-ribosylation factor, GTPase of the Ras superfamily\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				}
				]
			},
			{
				"name":"Arf6-dependent endocytosis",
				"children":[
				{
					"name":"PAS_chr4_0214 Glucose-repressible ADP-ribosylation factor\tK07941 ARF6; ADP-ribosylation factor 6"
				},
				{
					"name":"PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				}
				]
			},
			{
				"name":"RhoA-dependent endocytosis",
				"children":[
				{
					"name":"PAS_chr3_0150 GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell pol\tK04513 RHOA; Ras homolog gene family, member A"
				},
				{
					"name":"PAS_chr3_0751 Dynamin-related GTPase\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			}
			]
		},
		{
			"name":"Phagocytosis",
			"children":[
			{
				"name":"Fc receptors"
			},
			{
				"name":"Integrins (complement receptors)"
			},
			{
				"name":"Opsonins"
			},
			{
				"name":"Toll-like receptors"
			},
			{
				"name":"C-lectin receptors"
			},
			{
				"name":"Scavenger receptors"
			},
			{
				"name":"Coronins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr4_0618 One of two type I myosins\tK10356 MYO1; myosin I"
				}
				]
			}
			]
		},
		{
			"name":"Macropinocytosis",
			"children":[
			{
				"name":"Ras GTPases",
				"children":[
				{
					"name":"PAS_chr3_0133 GTP-binding protein of the ras superfamily required for bud site selection\tK07827 KRAS; GTPase KRas"
				},
				{
					"name":"PAS_chr4_0680 GTP-binding protein\tK07827 KRAS; GTPase KRas"
				},
				{
					"name":"PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				},
				{
					"name":"PAS_chr2-1_0112 Small rho-like GTPase, essential for establishment and maintenance of cell polarity\tK04393 CDC42; cell division control protein 42"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"PAS_c131_0004 hypothetical protein\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipase C",
				"children":[
				{
					"name":"PAS_chr4_0700 Phospholipase C\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				}
				]
			},
			{
				"name":"Sorting nexins",
				"children":[
				{
					"name":"PAS_chr3_0990 Nexin-1 homolog required for localizing membrane proteins\tK17917 SNX1_2; sorting nexin-1\/2"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Bin\/Amphiphysin\/Rvs (BAR) family proteins",
			"children":[
			{
				"name":"N-BAR proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0116 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p)\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr3_0498 Actin-associated protein\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr3_0983 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p)\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr1-4_0384 Amphiphysin-like lipid raft protein\tK20120 BIN3; bridging integrator 3"
				},
				{
					"name":"PAS_chr3_0833 Amphiphysin-like lipid raft protein\tK20120 BIN3; bridging integrator 3"
				}
				]
			},
			{
				"name":"F-BAR proteins",
				"children":[
				{
					"name":"PAS_chr4_0215 SH3 domain protein implicated in the regulation of actin polymerization\tK20121 FNBP1; formin-binding protein 1"
				},
				{
					"name":"PAS_chr3_0865 Protein with a potential role in actin cytoskeletal organization\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"PAS_chr4_0681 GTPase-activating protein (RhoGAP) for Rho3p and Rho4p\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				}
				]
			},
			{
				"name":"I-BAR proteins"
			}
			]
		},
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"PAS_chr1-4_0162 GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5\tK07888 RAB5B; Ras-related protein Rab-5B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"PAS_chr3_0203 Guanine nucleotide exchange factor\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"PAS_chr2-1_0830 hypothetical protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"PAS_chr3_0042 Myristoylated serine\/threonine protein kinase involved in vacuolar protein sorting\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr1-1_0150 Protein of the Sec1p\/Munc-18 family, essential for vacuolar protein sorting\tK12479 VPS45; vacuolar protein sorting-associated protein 45"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"PAS_chr2-2_0087 ADP-ribosylation factor, GTPase of the Ras superfamily\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"PAS_chr4_0214 Glucose-repressible ADP-ribosylation factor\tK07941 ARF6; ADP-ribosylation factor 6"
				}
				]
			},
			{
				"name":"Arf associated proteins",
				"children":[
				{
					"name":"PAS_chr1-4_0340 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"PAS_chr3_1109 Protein that localizes to the nucleus and is involved in transcription regulation\tK12486 SMAP; stromal membrane-associated protein"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Fucosyltransferase"
			},
			{
				"name":"EFR3-PI4KIII alpha complex and associated proteins",
				"children":[
				{
					"name":"PAS_chr1-3_0100 Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"PAS_chr1-3_0180 hypothetical protein\tK21842 EFR3; protein EFR3"
				},
				{
					"name":"PAS_chr3_0536 hypothetical protein\tK21845 YPP1; cargo-transport protein YPP1"
				}
				]
			},
			{
				"name":"Insulin-like growth factor-binding proteins"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Lysosome transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"PAS_chr1-4_0162 GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5\tK07888 RAB5B; Ras-related protein Rab-5B"
				},
				{
					"name":"PAS_chr2-1_0669 GTPase\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				},
				{
					"name":"PAS_chr4_0899 GTP-binding protein\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"FTS\/Hook\/FHIP (FHF) complex"
			},
			{
				"name":"FERRY complex"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"PAS_chr3_0450 Alpha 4 subunit of the 20S proteasome\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"PAS_c121_0003 hypothetical protein\tK18469 TBC1D5; TBC1 domain family member 5"
				},
				{
					"name":"PAS_chr1-3_0254 GTPase-activating protein for yeast Rab family members\tK20168 TBC1D15; TBC1 domain family member 15"
				},
				{
					"name":"PAS_chr3_0586 Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"PAS_chr4_0741 Alpha subunit of Type II geranylgeranyltransferase\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"PAS_chr3_0764 Beta subunit of Type II geranylgeranyltransferase\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"PAS_chr2-1_0527 hypothetical protein\tK07955 ARL8; ADP-ribosylation factor-like protein 8"
				}
				]
			},
			{
				"name":"BLOC-one-related complex (BORC)"
			},
			{
				"name":"N-acetyl transferase complex C (NatC)",
				"children":[
				{
					"name":"PAS_chr3_0234 Catalytic subunit of N-terminal acetyltransferase of the NatC type\tK00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]"
				},
				{
					"name":"PAS_chr1-1_0190 Non-catalytic subunit of N-terminal acetyltransferase of the NatC type\tK20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit"
				},
				{
					"name":"PAS_chr3_0780 hypothetical protein\tK20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit"
				}
				]
			},
			{
				"name":"Other Arf associated proteins"
			}
			]
		},
		{
			"name":"Endosomal sorting complexes required for transport (ESCRT)",
			"children":[
			{
				"name":"ESCRT-0 complex",
				"children":[
				{
					"name":"PAS_FragB_0049 Vacuolar protein sorting-associated protein 27\tK12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate"
				},
				{
					"name":"PAS_c131_0007 hypothetical protein\tK04705 STAM; signal transducing adaptor molecule"
				}
				]
			},
			{
				"name":"ESCRT-I complex",
				"children":[
				{
					"name":"PAS_chr3_0136 Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into\tK12183 TSG101; ESCRT-I complex subunit TSG101"
				},
				{
					"name":"PAS_chr2-1_0182 Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, and Mvb12p), which is involved in ubiquitin\tK12184 VPS28; ESCRT-I complex subunit VPS28"
				}
				]
			},
			{
				"name":"ESCRT-II complex",
				"children":[
				{
					"name":"PAS_chr3_1165 hypothetical protein\tK12188 SNF8; ESCRT-II complex subunit VPS22"
				},
				{
					"name":"PAS_chr4_0993 hypothetical protein\tK12189 VPS25; ESCRT-II complex subunit VPS25"
				},
				{
					"name":"PAS_chr3_0312 Component of the ESCRT-II complex\tK12190 VPS36; ESCRT-II complex subunit VPS36"
				}
				]
			},
			{
				"name":"ESCRT-III complex",
				"children":[
				{
					"name":"PAS_chr1-4_0657 Vacuolar protein sorting protein\tK12197 CHMP1; charged multivesicular body protein 1"
				},
				{
					"name":"PAS_c131_0013 hypothetical protein\tK12191 CHMP2A; charged multivesicular body protein 2A"
				},
				{
					"name":"PAS_chr1-1_0034 vacuolar sorting protein\tK12193 VPS24; charged multivesicular body protein 3"
				},
				{
					"name":"PAS_chr1-4_0023 One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III)\tK12194 CHMP4A_B; charged multivesicular body protein 4A\/B"
				},
				{
					"name":"PAS_chr3_0168 Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport\tK12198 CHMP5; charged multivesicular body protein 5"
				},
				{
					"name":"PAS_chr4_0420 Myristoylated subunit of ESCRTIII\tK12195 CHMP6; charged multivesicular body protein 6"
				},
				{
					"name":"PAS_chr1-3_0288 hypothetical protein\tK15053 CHMP7; charged multivesicular body protein 7"
				},
				{
					"name":"PAS_chr2-1_0572 AAA-type ATPase that is regulated by Vta1p\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				}
				]
			},
			{
				"name":"ESCRT associated proteins",
				"children":[
				{
					"name":"PAS_chr4_0635 hypothetical protein\tK12199 VTA1; vacuolar protein sorting-associated protein VTA1"
				},
				{
					"name":"PAS_chr1-3_0184 Protein involved in proteolytic activation of Rim101p in response to alkaline pH\tK12200 PDCD6IP; programmed cell death 6-interacting protein"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"CORVET complex",
				"children":[
				{
					"name":"PAS_chr3_1175 hypothetical protein\tK20177 VPS3; vacuolar protein sorting-associated protein 3"
				},
				{
					"name":"PAS_chr1-4_0606 Membrane-associated protein\tK20178 VPS8; vacuolar protein sorting-associated protein 8"
				},
				{
					"name":"PAS_chr1-3_0306 hypothetical protein\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"PAS_chr3_0210 Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"PAS_chr2-1_0574 Component of CORVET tethering complex\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"PAS_chr2-2_0264 ATP-binding protein that is A subunit of the HOPS complex and the CORVET tethering complex\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				}
				]
			},
			{
				"name":"Hops complex",
				"children":[
				{
					"name":"PAS_chr1-3_0306 hypothetical protein\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"PAS_chr3_0210 Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"PAS_chr2-1_0574 Component of CORVET tethering complex\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"PAS_chr2-2_0264 ATP-binding protein that is A subunit of the HOPS complex and the CORVET tethering complex\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				},
				{
					"name":"PAS_chr1-1_0460 hypothetical protein\tK20183 VPS39; Vam6\/Vps39-like protein vacuolar protein sorting-associated protein 39"
				},
				{
					"name":"PAS_chr4_0062 Vacuolar membrane protein\tK20184 VPS41; vacuolar protein sorting-associated protein 41"
				}
				]
			}
			]
		},
		{
			"name":"Acidification regulators",
			"children":[
			{
				"name":"Rabconnectin-3 complex",
				"children":[
				{
					"name":"PAS_chr2-1_0345 Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"RAVE complex",
				"children":[
				{
					"name":"PAS_chr2-1_0345 Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzym\tK24155 DMXL; rabconnectin-3a"
				},
				{
					"name":"PAS_chr3_0390 Subunit of RAVE (Rav1p, Rav2p, Skp1p)\tK25485 RAV2; regulator of V-ATPase in vacuolar membrane protein 2"
				},
				{
					"name":"PAS_chr3_1258 hypothetical protein\tK03094 SKP1; S-phase kinase-associated protein 1"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"PAS_FragB_0027 AP-3 complex subunit delta\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"PAS_chr2-2_0415 Beta3-like subunit of the yeast AP-3 complex\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"PAS_chr2-1_0788 Mu3-like subunit of the clathrin associated protein complex (AP-3)\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"PAS_chr3_0122 Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"BLOC-1 complex"
			},
			{
				"name":"BLOC-1 complex (yeast)",
				"children":[
				{
					"name":"PAS_chr4_0296 hypothetical protein\tK22240 CNL1; biogenesis of lysosome-related organelles complex 1 subunit CNL1"
				},
				{
					"name":"PAS_chr4_0611 hypothetical protein\tK22241 SNN1; biogenesis of lysosome-related organelles complex 1 subunit SNN1"
				},
				{
					"name":"PAS_FragB_0026 hypothetical protein\tK22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1"
				}
				]
			},
			{
				"name":"BLOC-2 complex"
			},
			{
				"name":"BLOC-3 complex"
			},
			{
				"name":"Ferlins"
			},
			{
				"name":"Lysosomal membrane proteins",
				"children":[
				{
					"name":"PAS_FragD_0019 Putative protein of unknown function\tK13526 ATP13A2; cation-transporting P-type ATPase 13A2 [EC:7.2.2.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr3_1107 Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole\tK20195 MON1; vacuolar fusion protein MON1"
				},
				{
					"name":"PAS_chr4_0614 hypothetical protein\tK21156 CCZ1; vacuolar fusion protein CCZ1, fungi type"
				},
				{
					"name":"PAS_chr1-3_0261 Ubiquitin isopeptidase\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"PAS_chr2-2_0056 hypothetical protein\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"PAS_chr2-1_0290 Late endosomal protein involved in late endosome to vacuole trafficking\tK28212 LEPROT; OB-RGRP\/VPS55 family protein"
				},
				{
					"name":"PAS_chr3_1181 hypothetical protein\tK28212 LEPROT; OB-RGRP\/VPS55 family protein"
				},
				{
					"name":"PAS_chr4_0811 Vacuolar membrane protein of unknown function involved in vacuolar protein sorting\tK29023 VPS68; vacuolar protein sorting-associated protein 68"
				},
				{
					"name":"PAS_chr1-4_0644 Dynamin-like GTPase required for vacuolar sorting\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"PAS_chr3_0606 PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins\tK24781 BPH1; beige protein homolog 1"
				},
				{
					"name":"PAS_chr1-4_0512 hypothetical protein\tK28441 TAG1; protein TAG1"
				},
				{
					"name":"PAS_chr2-2_0042 Specificity factor required for Rsp5p-dependent ubiquitination\tK28544 SSH4; SSH4 family protein"
				},
				{
					"name":"PAS_chr3_0508 Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins\tK28544 SSH4; SSH4 family protein"
				},
				{
					"name":"PAS_chr1-4_0178 Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway\tK28545 RCR; protein RCR"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein recycling",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"PAS_chr1-4_0528 GTPase of the Ypt\/Rab family, very similar to Ypt31p\tK07905 RAB11B; Ras-related protein Rab-11B"
				}
				]
			},
			{
				"name":"Rab4 associated proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0830 hypothetical protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"PAS_chr2-1_0389 Sorting nexin\tK17919 SNX4; sorting nexin-4"
				}
				]
			},
			{
				"name":"Rab11 associated proteins",
				"children":[
				{
					"name":"PAS_chr1-1_0471 hypothetical protein\tK20241 WDR44; WD repeat-containing protein 44"
				},
				{
					"name":"PAS_chr1-3_0057 Component of both the Nup84 nuclear pore sub-complex and of the COPII complex\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"PAS_chr2-1_0297 Essential 113kDa subunit of the exocyst complex\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"PAS_FragB_0038 GTPase-activating protein\tK20242 EVI5; ecotropic viral integration site 5 protein"
				},
				{
					"name":"PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			},
			{
				"name":"Other Rab GTPase associated proteins",
				"children":[
				{
					"name":"PAS_chr3_0203 Guanine nucleotide exchange factor\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"PAS_chr3_0904 Strand exchange protein, forms a helical filament with DNA that searches for homology\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Glutamate receptor-interacting proteins (GRIPs)"
			},
			{
				"name":"GRIP associated proteins"
			},
			{
				"name":"EARP complex",
				"children":[
				{
					"name":"PAS_chr1-3_0031 Golgi-associated retrograde protein\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"PAS_chr3_0301 Component of the GARP (Golgi-associated retrograde protein) complex\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				}
				]
			},
			{
				"name":"WASH complex",
				"children":[
				{
					"name":"PAS_c131_0006 hypothetical protein\tK10364 CAPZA; F-actin-capping protein subunit alpha"
				},
				{
					"name":"PAS_chr3_0548 Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p)\tK10365 CAPZB; F-actin-capping protein subunit beta"
				}
				]
			},
			{
				"name":"Retriever complex",
				"children":[
				{
					"name":"PAS_chr3_1146 hypothetical protein\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				}
				]
			},
			{
				"name":"CCC complex"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_FragB_0002 Protein CSF1\tK24964 BLTP1; Bridge-like lipid transfer protein family member 1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Golgi transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"PAS_chr2-1_0669 GTPase\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				},
				{
					"name":"PAS_chr4_0899 GTP-binding protein\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"Retromer subcomplex",
				"children":[
				{
					"name":"PAS_chr1-4_0503 Endosomal subunit of membrane-associated retromer complex required for retrograde transport\tK18468 VPS35; vacuolar protein sorting-associated protein 35"
				},
				{
					"name":"PAS_chr3_1146 hypothetical protein\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				},
				{
					"name":"PAS_chr4_0074 Vacuolar protein sorting protein\tK18466 VPS26A_B; vacuolar protein sorting-associated protein 26A\/B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"PAS_chr3_0801 Cytoplasmic GTPase-activating protein for Ypt\/Rab transport GTPases Ypt6p, Ypt31p and Sec4p\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"PAS_chr2-1_0682 hypothetical protein\tK20286 TMF1; TATA element modulatory factor"
				},
				{
					"name":"PAS_chr4_0389 Large subunit of the dynactin complex\tK04648 DCTN1; dynactin 1"
				},
				{
					"name":"PAS_chr1-1_0211 Putative vacuolar protein sorting-associated protein vps13\tK19525 VPS13A_C; vacuolar protein sorting-associated protein 13A\/C"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"PAS_chr2-2_0087 ADP-ribosylation factor, GTPase of the Ras superfamily\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"PAS_chr2-2_0316 Soluble GTPase with a role in regulation of membrane traffic\tK07942 ARL1; ADP-ribosylation factor-like protein 1"
				},
				{
					"name":"PAS_chr2-2_0078 GTPase of the Ras superfamily required to recruit Arl1p to the Golgi\tK07952 ARFRP1; ADP-ribosylation factor related protein 1"
				}
				]
			},
			{
				"name":"Arf GTPase associated proteins",
				"children":[
				{
					"name":"PAS_chr3_0974 ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport\tK12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1"
				},
				{
					"name":"PAS_chr3_0559 ADP-ribosylation factor GTPase activating protein (ARF GAP)\tK12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2\/3"
				},
				{
					"name":"PAS_chr1-4_0340 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"PAS_chr3_1109 Protein that localizes to the nucleus and is involved in transcription regulation\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"PAS_chr1-4_0667 hypothetical protein\tK18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein"
				},
				{
					"name":"PAS_chr1-4_0432 Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs)\tK18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Conserved oligomeric Golgi (COG) complex",
				"children":[
				{
					"name":"PAS_chr3_0206 hypothetical protein\tK20289 COG2; conserved oligomeric Golgi complex subunit 2"
				},
				{
					"name":"PAS_chr4_0916 hypothetical protein\tK20290 COG3; conserved oligomeric Golgi complex subunit 3"
				},
				{
					"name":"PAS_chr1-1_0250 Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p)\tK20291 COG4; conserved oligomeric Golgi complex subunit 4"
				},
				{
					"name":"PAS_chr4_0073 Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p)\tK20293 COG6; conserved oligomeric Golgi complex subunit 6"
				},
				{
					"name":"PAS_chr2-2_0228 hypothetical protein\tK20295 COG8; conserved oligomeric Golgi complex subunit 8"
				}
				]
			},
			{
				"name":"GARP complex",
				"children":[
				{
					"name":"PAS_chr4_0693 hypothetical protein\tK20297 VPS51; vacuolar protein sorting-associated protein 51"
				},
				{
					"name":"PAS_chr1-3_0031 Golgi-associated retrograde protein\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"PAS_chr3_0301 Component of the GARP (Golgi-associated retrograde protein) complex\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				},
				{
					"name":"PAS_chr1-1_0314 Component of the GARP (Golgi-associated retrograde protein) complex\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
				}
				]
			},
			{
				"name":"TRAPP complex II",
				"children":[
				{
					"name":"PAS_chr2-2_0224 Component of the TRAPP (transport protein particle) complex\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"PAS_chr2-1_0476 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"PAS_chr1-3_0080 Hydrophilic protein that acts in conjunction with SNARE proteins\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"PAS_chr2-2_0180 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"PAS_chr1-3_0091 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"PAS_chr3_1098 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				},
				{
					"name":"PAS_chr2-1_0774 Subunit of TRAPP (transport protein particle)\tK20305 TRAPPC8; trafficking protein particle complex subunit 8"
				},
				{
					"name":"PAS_chr2-1_0811 hypothetical protein\tK20306 TRAPPC9; trafficking protein particle complex subunit 9"
				},
				{
					"name":"PAS_chr2-1_0532 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi\tK20307 TRAPPC10; trafficking protein particle complex subunit 10"
				},
				{
					"name":"PAS_chr2-2_0374 hypothetical protein\tK20308 TRAPPC11; trafficking protein particle complex subunit 11"
				},
				{
					"name":"PAS_chr4_0721 hypothetical protein\tK20311 TRS65; trafficking protein particle complex II-specific subunit 65"
				},
				{
					"name":"PAS_chr4_0371 hypothetical protein\tK20312 TCA17; TRAPP-associated protein TCA17"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-1 complex",
				"children":[
				{
					"name":"PAS_chr2-1_0537 Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex\tK12391 AP1G1; AP-1 complex subunit gamma-1"
				},
				{
					"name":"PAS_chr1-4_0010 Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex\tK12392 AP1B1; AP-1 complex subunit beta-1"
				},
				{
					"name":"PAS_chr1-4_0112 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1)\tK12393 AP1M; AP-1 complex subunit mu"
				},
				{
					"name":"PAS_chr4_0852 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1)\tK12393 AP1M; AP-1 complex subunit mu"
				},
				{
					"name":"PAS_chr1-3_0140 Small subunit of the clathrin-associated adaptor complex AP-1\tK12394 AP1S1_2; AP-1 complex subunit sigma 1\/2"
				}
				]
			},
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"PAS_FragB_0027 AP-3 complex subunit delta\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"PAS_chr2-2_0415 Beta3-like subunit of the yeast AP-3 complex\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"PAS_chr2-1_0788 Mu3-like subunit of the clathrin associated protein complex (AP-3)\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"PAS_chr3_0122 Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"AP-4 complex"
			},
			{
				"name":"GGA",
				"children":[
				{
					"name":"PAS_chr4_0297 Golgi-localized protein with homology to gamma-adaptin\tK12404 GGA; ADP-ribosylation factor-binding protein GGA"
				}
				]
			},
			{
				"name":"Aftiphilin\/p200\/gamma-synergin complex",
				"children":[
				{
					"name":"PAS_chr2-2_0037 AP-1 accessory protein\tK24814 HEATR5; HEAT repeat-containing protein 5"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr3_0646 Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				},
				{
					"name":"PAS_chr1-3_0100 Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"PAS_chr1-1_0457 Phosphatidylinositol-4-phosphate 5-kinase\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"PAS_chr3_1215 hypothetical protein\tK20318 SYS1; protein SYS1"
				},
				{
					"name":"PAS_chr2-2_0062 Putative protein of unknown function\tK23541 TMEM165; Ca2+\/H+ antiporter, TMEM165\/GDT1 family"
				},
				{
					"name":"PAS_chr1-1_0423 hypothetical protein\tK23542 TMEM199; TMEM199 family protein"
				},
				{
					"name":"PAS_chr1-1_0493 hypothetical protein\tK23543 CCDC115; coiled-coil domain-containing protein 115"
				},
				{
					"name":"PAS_chr2-1_0793 Vacuolar membrane protein of unknown function that is conserved in mammals\tK23544 SERINC1; serine incorporator 1"
				},
				{
					"name":"PAS_chr3_0639 Sorting nexin\tK17918 SNX3_12; sorting nexin-3\/12"
				},
				{
					"name":"PAS_chr3_0269 Protein required for sorting proteins to the vacuole\tK17922 SNX8; sorting nexin-8"
				},
				{
					"name":"PAS_chr2-1_0066 Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p A\tK26678 MON2; protein MON2"
				},
				{
					"name":"PAS_chr2-1_0180 Protein of unknown function, essential for viability\tK26680 DOP1; protein dopey"
				},
				{
					"name":"PAS_chr3_0412 hypothetical protein\tK27894 HID1; protein HID1"
				},
				{
					"name":"PAS_chr2-1_0104 hypothetical protein\tK26750 TVP15; golgi apparatus membrane protein TVP15"
				},
				{
					"name":"PAS_chr2-1_0239 Integral membrane protein localized to late Golgi vesicles along with the V-SNARE Tlg2p\tK26751 TVP18; golgi apparatus membrane protein TVP18"
				},
				{
					"name":"PAS_chr2-2_0091 Integral membrane protein localized to late Golgi vesicles along with the V-SNARE Tlg2p\tK26752 TVP23; golgi apparatus membrane protein TVP23"
				},
				{
					"name":"PAS_chr4_0758 Integral membrane protein localized to late Golgi vesicles along with the V-SNARE Tlg2p\tK26753 TVP38; golgi apparatus membrane protein TVP38"
				},
				{
					"name":"PAS_chr1-4_0644 Dynamin-like GTPase required for vacuolar sorting\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"PAS_chr2-1_0625 Type I transmembrane sorting receptor for multiple vacuolar hydrolases\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"PAS_chr3_0653 Type I transmembrane sorting receptor for multiple vacuolar hydrolases\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"PAS_chr2-1_0789 Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde prote\tK28986 VPS17; vacuolar protein sorting-associated protein 17"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endoplasmic reticulum (ER) - Golgi transport",
		"children":[
		{
			"name":"Forward pathways",
			"children":[
			{
				"name":"Coat protein complex II (COP-II)",
				"children":[
				{
					"name":"PAS_chr1-1_0180 GTPase; GTP-binding protein of the ARF family, component of COPII coat of vesicles\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				},
				{
					"name":"PAS_chr1-3_0057 Component of both the Nup84 nuclear pore sub-complex and of the COPII complex\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"PAS_chr1-4_0231 Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles\tK14005 SEC31; protein transport protein SEC31"
				},
				{
					"name":"PAS_chr1-1_0048 GTPase-activating protein\tK14006 SEC23; protein transport protein SEC23"
				},
				{
					"name":"PAS_chr4_0600 GTPase-activating protein\tK14006 SEC23; protein transport protein SEC23"
				},
				{
					"name":"PAS_chr3_0614 Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"PAS_chr4_0484 Member of the Sec24p family\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"PAS_chr4_0606 Guanine nucleotide exchange factor (GEF)\tK14003 PREB; prolactin regulatory element-binding protein"
				}
				]
			},
			{
				"name":"TRAPP complex I",
				"children":[
				{
					"name":"PAS_chr2-2_0224 Component of the TRAPP (transport protein particle) complex\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"PAS_chr2-1_0476 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"PAS_chr1-3_0080 Hydrophilic protein that acts in conjunction with SNARE proteins\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"PAS_chr2-2_0180 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"PAS_chr1-3_0091 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"PAS_chr3_1098 One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				}
				]
			},
			{
				"name":"p24 family proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0564 Possible U3 snoRNP protein involved in maturation of pre-18S rRNA\tK20346 TMED4_9_11; p24 family protein alpha"
				},
				{
					"name":"PAS_chr2-1_0633 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles\tK20347 TMED2; p24 family protein beta-1"
				},
				{
					"name":"PAS_chr3_1259 hypothetical protein\tK20352 TMED10; p24 family protein delta-1"
				}
				]
			},
			{
				"name":"PDI family proteins",
				"children":[
				{
					"name":"PAS_chr4_0844 Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
				},
				{
					"name":"PAS_chr1-1_0160 Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
				},
				{
					"name":"PAS_chr1-3_0125 Member of the protein disulfide isomerase (PDI) family\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
				},
				{
					"name":"PAS_chr4_0991 hypothetical protein\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
				}
				]
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"PAS_chr3_1167 hypothetical protein\tK07874 RAB1A; Ras-related protein Rab-1A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"PAS_chr1-4_0120 Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport\tK20359 RABAC1; PRA1 family protein 1"
				},
				{
					"name":"PAS_chr2-1_0484 Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport\tK20359 RABAC1; PRA1 family protein 1"
				},
				{
					"name":"PAS_chr1-4_0364 Rab GTPase-activating protein\tK20372 TBC1D20; TBC1 domain family member 20"
				},
				{
					"name":"PAS_chr1-3_0219 Cis-golgi GTPase-activating protein (GAP)\tK20360 TBC1D22; TBC1 domain family member 2"
				},
				{
					"name":"PAS_chr1-3_0082 Integral membrane protein\tK20362 YIF1; protein transport protein YIF1"
				},
				{
					"name":"PAS_chr1-3_0062 Integral membrane protein required for ER to Golgi transport\tK22939 IER3IP1; immediate early response 3-interacting protein 1"
				},
				{
					"name":"PAS_chr4_0088 Essential protein involved in intracellular protein transport\tK20361 USO1; intracellular protein transport protein USO1"
				}
				]
			},
			{
				"name":"ER-Golgi intermediate compartment (ERGIC) proteins",
				"children":[
				{
					"name":"PAS_chr4_0432 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles\tK10080 LMAN1; lectin, mannose-binding 1"
				},
				{
					"name":"PAS_chr2-2_0178 hypothetical protein\tK10082 LMAN2; lectin, mannose-binding 2"
				},
				{
					"name":"PAS_chr2-1_0753 Alpha-1,2-mannosidase involved in ER quality control\tK23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]"
				},
				{
					"name":"PAS_chr3_0875 Protein localized to COPII-coated vesicles, forms a complex with Erv46p\tK20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2"
				},
				{
					"name":"PAS_chr2-1_0796 Protein localized to COPII-coated vesicles, forms a complex with Erv41p\tK20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3"
				},
				{
					"name":"PAS_chr1-4_0225 ER-derived vesicles protein ERV14\tK20368 CNIH; protein cornichon"
				},
				{
					"name":"PAS_chr2-1_0287 Protein localized to COPII-coated vesicles\tK20369 ERV29; ER-derived vesicles protein"
				},
				{
					"name":"PAS_chr2-1_0140 ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding I\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"PAS_chr1-3_0236 Protein involved in retention of membrane proteins, including Sec12p, in the ER\tK29081 RER1; Rer1 family protein"
				}
				]
			}
			]
		},
		{
			"name":"Retrieval pathways",
			"children":[
			{
				"name":"Coat protein complex I (COP-I)",
				"children":[
				{
					"name":"PAS_chr1-1_0294 Alpha subunit of COPI vesicle coatomer complex\tK05236 COPA; coatomer subunit alpha"
				},
				{
					"name":"PAS_chr4_0798 Essential beta-coat protein of the COPI coatomer\tK17301 COPB1; coatomer subunit beta"
				},
				{
					"name":"PAS_chr1-1_0181 Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport\tK17302 COPB2; coatomer subunit beta'"
				},
				{
					"name":"PAS_chr4_0225 Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat\tK17267 COPG; coatomer subunit gamma"
				},
				{
					"name":"PAS_chr1-1_0035 Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles\tK20471 COPD; coatomer subunit delta"
				},
				{
					"name":"PAS_chr3_0690 Epsilon-COP subunit of the coatomer\tK17268 COPE; coatomer subunit epsilon"
				},
				{
					"name":"PAS_chr1-4_0317 Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles\tK20472 COPZ; coatomer subunit zeta"
				}
				]
			},
			{
				"name":"NRZ (DSL1) complex",
				"children":[
				{
					"name":"PAS_chr3_1248 hypothetical protein\tK20474 RINT1; RAD50-interacting protein 1"
				},
				{
					"name":"PAS_chr1-3_0088 hypothetical protein\tK11578 ZW10; protein transport protein DSL1\/ZW10"
				},
				{
					"name":"PAS_chr2-1_0440 hypothetical protein\tK20475 SEC39; protein transport protein SEC39"
				}
				]
			},
			{
				"name":"Golgi to ER traffic proteins (GET)",
				"children":[
				{
					"name":"PAS_chr4_0403 hypothetical protein\tK22384 GET1; tail-anchored protein insertion receptor"
				},
				{
					"name":"PAS_chr3_0197 hypothetical protein\tK22386 GET2; GET complex subunit GET2"
				},
				{
					"name":"PAS_chr4_0405 Guanine nucleotide exchange factor for Gpa1p\tK01551 arsA; arsenite\/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]"
				},
				{
					"name":"PAS_chr3_0280 hypothetical protein\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"Rab GTPases"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"PAS_chr4_0534 hypothetical protein\tK20476 RIC1; RAB6A-GEF complex partner protein 1"
				},
				{
					"name":"PAS_chr1-3_0067 Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6\tK20477 RGP1; RAB6A-GEF complex partner protein 2"
				},
				{
					"name":"PAS_chr4_0775 HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins\tK10949 KDELR; ER lumen protein retaining receptor"
				},
				{
					"name":"PAS_chr2-1_0830 hypothetical protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"PAS_chr1-3_0219 Cis-golgi GTPase-activating protein (GAP)\tK20360 TBC1D22; TBC1 domain family member 2"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Oxysterol-binding proteins",
				"children":[
				{
					"name":"PAS_chr3_0421 Member of an oxysterol-binding protein family with seven members in S. cerevisiae\tK20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3\/6\/7"
				},
				{
					"name":"PAS_chr1-4_0646 Oxysterol-binding protein\tK22285 OSBPL8; oxysterol-binding protein-related protein 8"
				},
				{
					"name":"PAS_chr1-4_0278 Member of the oxysterol binding protein family, which includes seven yeast homologs\tK20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9\/10\/11"
				}
				]
			},
			{
				"name":"FXYD proteins"
			},
			{
				"name":"YIPF proteins",
				"children":[
				{
					"name":"PAS_chr4_0870 hypothetical protein\tK22940 YIPF1_2; protein YIPF1\/2"
				},
				{
					"name":"PAS_chr2-1_0397 Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles\tK20363 YIPF5_7; protein YIPF5\/7"
				},
				{
					"name":"PAS_FragD_0007 hypothetical protein\tK22943 YIPF6; protein YIPF6"
				}
				]
			},
			{
				"name":"ER membrane protein complex",
				"children":[
				{
					"name":"PAS_chr2-1_0327 hypothetical protein\tK23562 EMC1; ER membrane protein complex subunit 1"
				},
				{
					"name":"PAS_chr4_0765 Putative protein of unknown function\tK23563 EMC2; ER membrane protein complex subunit 2"
				},
				{
					"name":"PAS_chr2-1_0551 Putative protein of unknown function\tK23564 EMC3; ER membrane protein complex subunit 3"
				},
				{
					"name":"PAS_chr2-1_0296 Putative protein of unknown function\tK23565 EMC4; ER membrane protein complex subunit 4"
				},
				{
					"name":"PAS_chr3_0541 hypothetical protein\tK23566 MMGT1; membrane magnesium transporter 1"
				},
				{
					"name":"PAS_chr4_0517 Putative protein of unknown function\tK23567 EMC6; ER membrane protein complex subunit 6"
				}
				]
			},
			{
				"name":"SEC61 complex",
				"children":[
				{
					"name":"PAS_chr1-3_0202 Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p)\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"PAS_chr1-4_0629 Subunit of the Ssh1 translocon complex\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"PAS_chr2-2_0210 Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p)\tK09481 SEC61B; protein transport protein SEC61 subunit beta"
				},
				{
					"name":"PAS_chr1-1_0023 hypothetical protein\tK07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins"
				}
				]
			},
			{
				"name":"TRAP complex"
			},
			{
				"name":"Multi-pass translocon (MPT) complex",
				"children":[
				{
					"name":"PAS_chr3_0464 Putative protein of unknown function\tK24962 CCDC47; PAT complex subunit CCDC47"
				}
				]
			},
			{
				"name":"Post-GPI attachment to proteins factors (PGAP)",
				"children":[
				{
					"name":"PAS_chr2-1_0699 GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation\tK05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]"
				},
				{
					"name":"PAS_chr2-2_0114 Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity\tK23553 PGAP3; post-GPI attachment to proteins factor 3"
				},
				{
					"name":"PAS_chr1-4_0333 hypothetical protein\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				},
				{
					"name":"PAS_chr3_0423 Putative membrane protein of unknown function involved in Mn2+ homeostasis\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				},
				{
					"name":"PAS_chr3_0483 Conserved phosphoesterase domain-containing protein\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr4_0251 Hydrophilic protein, involved in vesicle trafficking between the ER and Golgi\tK19998 SCFD1; sec1 family domain-containing protein 1"
				},
				{
					"name":"PAS_chr3_0229 hypothetical protein\tK20724 TMEM33; transmembrane protein 33"
				},
				{
					"name":"PAS_chr4_0551 hypothetical protein\tK20724 TMEM33; transmembrane protein 33"
				},
				{
					"name":"PAS_chr4_0483 Protein required for normal intracellular sterol distribution and for sphingolipid metabolism\tK21848 ARV1; lipid intermediate transporter"
				},
				{
					"name":"PAS_chr1-3_0133 hypothetical protein\tK21849 KEG1; beta-1,6-glucan synthesis-associated protein KEG1"
				},
				{
					"name":"PAS_chr4_0508 Protein required for beta-1,6 glucan biosynthesis\tK21850 KRE6; beta-glucan synthesis-associated protein KRE6"
				},
				{
					"name":"PAS_chr3_0108 Protein required for Golgi localization of glycosyltransferases\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"PAS_chr2-1_0884 hypothetical protein\tK23292 LNPK; endoplasmic reticulum junction formation protein lunapark"
				},
				{
					"name":"PAS_chr1-3_0097 hypothetical protein\tK26681 INSIG; insulin-induced protein"
				},
				{
					"name":"PAS_chr1-1_0271 Evolutionarily conserved non-essential protein present in early Golgi cisternae\tK26683 GOLT1; vesicle transport protein GOT1"
				},
				{
					"name":"PAS_chr3_0279 Protein of unknown function, contains two predicted GTP-binding motifs\tK22698 SEY1; protein SEY1 [EC:3.6.5.-]"
				},
				{
					"name":"PAS_chr2-2_0296 Putative protein of unknown function\tK29087 NVJ2; nucleus-vacuole junction protein 2"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Autophagy",
		"children":[
		{
			"name":"Autophagosome formation proteins",
			"children":[
			{
				"name":"ULK complex",
				"children":[
				{
					"name":"PAS_chr2-2_0432 Regulatory subunit of the Atg1p signaling complex\tK08331 ATG13; autophagy-related protein 13"
				},
				{
					"name":"PAS_chr3_0501 hypothetical protein\tK19730 ATG101; autophagy-related protein 101"
				}
				]
			},
			{
				"name":"Atg1 complex",
				"children":[
				{
					"name":"PAS_chr2-1_0641 Protein serine\/threonine kinase required for vesicle formation in autophagy\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr2-2_0432 Regulatory subunit of the Atg1p signaling complex\tK08331 ATG13; autophagy-related protein 13"
				},
				{
					"name":"PAS_chr2-1_0672 Scaffold protein responsible for pre-autophagosomal structure organization\tK08329 ATG17; autophagy-related protein 17"
				}
				]
			},
			{
				"name":"PI3K complex",
				"children":[
				{
					"name":"PAS_chr4_0478 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"PAS_chr3_0042 Myristoylated serine\/threonine protein kinase involved in vacuolar protein sorting\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr2-1_0211 Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II\tK08334 BECN; beclin"
				}
				]
			},
			{
				"name":"ATG9 transmembrane protein",
				"children":[
				{
					"name":"PAS_chr4_0510 Transmembrane protein involved in formation of Cvt and autophagic vesicles\tK17907 ATG9; autophagy-related protein 9"
				}
				]
			},
			{
				"name":"Atg18-Atg2 complex",
				"children":[
				{
					"name":"PAS_chr3_0931 Phosphoinositide binding protein required for vesicle formation in autophagy\tK17908 WIPI1_2; autophagy-related protein 18"
				},
				{
					"name":"PAS_chr3_1016 Phosphoinositide binding protein\tK17908 WIPI1_2; autophagy-related protein 18"
				},
				{
					"name":"PAS_chr1-3_0168 Peripheral membrane protein required for vesicle formation\tK17906 ATG2; autophagy-related protein 2"
				}
				]
			},
			{
				"name":"Atg12 conjugation proteins",
				"children":[
				{
					"name":"PAS_chr3_0363 Conserved ubiquitin-like modifier\tK08336 ATG12; ubiquitin-like protein ATG12"
				},
				{
					"name":"PAS_chr1-4_0310 Autophagy-related protein\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"PAS_chr4_0459 Conserved protein involved in autophagy and the Cvt pathway\tK08339 ATG5; autophagy-related protein 5"
				}
				]
			},
			{
				"name":"Atg8 conjugation proteins",
				"children":[
				{
					"name":"PAS_chr4_0704 Conserved protein that is a component of autophagosomes and Cvt vesicles\tK08341 GABARAP; GABA(A) receptor-associated protein"
				},
				{
					"name":"PAS_chr1-4_0522 Conserved cysteine protease required for autophagy\tK08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]"
				},
				{
					"name":"PAS_chr1-4_0310 Autophagy-related protein\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"PAS_chr3_0688 E2-like enzyme involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
				}
				]
			}
			]
		},
		{
			"name":"Cytoplasm to vacuolar targeting (CVT) pathway",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"PAS_chr3_0803 Vacuolar aminopeptidase\tK01268 LAP4; aminopeptidase I [EC:3.4.11.22]"
				},
				{
					"name":"PAS_chr4_0790 Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"PAS_chr4_0913 hypothetical protein\tK01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]"
				}
				]
			},
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold protein",
				"children":[
				{
					"name":"PAS_chr1-4_0555 Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway\tK08330 ATG11; autophagy-related protein 11"
				}
				]
			},
			{
				"name":"Other Cvt associated proteins",
				"children":[
				{
					"name":"PAS_chr2-2_0030 Sorting nexin family member\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"PAS_chr3_1139 Sorting nexin\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"PAS_chr2-1_0389 Sorting nexin\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"PAS_chr1-1_0465 hypothetical protein\tK17900 ATG15; lipase ATG15 [EC:3.1.1.3]"
				},
				{
					"name":"PAS_chr2-2_0110 Type I membrane protein involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway\tK21141 ATG27; autophagy-related protein 27"
				},
				{
					"name":"PAS_chr1-4_0101 Phosphorylated vacuolar membrane protein that interacts with Atg13p\tK08332 VAC8; vacuolar protein 8"
				}
				]
			}
			]
		},
		{
			"name":"Mitophagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold proteins",
				"children":[
				{
					"name":"PAS_chr1-4_0555 Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway\tK08330 ATG11; autophagy-related protein 11"
				}
				]
			},
			{
				"name":"PINK1-Parkin associated proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0285 Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenanceof the mitoc\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"Other mitophagy associated  proteins",
				"children":[
				{
					"name":"PAS_chr1-4_0447 Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"PAS_chr1-4_0561 Hexokinase-2\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"PAS_chr3_1192 hypothetical protein\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"PAS_chr4_0624 Non-essential protein of unknown function required for transcriptional induction\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"PAS_chr1-1_0315 Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase\tK22255 ATPIF1; ATPase inhibitor, mitochondrial"
				},
				{
					"name":"PAS_chr3_1190 hypothetical protein\tK17771 TOM7; mitochondrial import receptor subunit TOM7"
				},
				{
					"name":"PAS_chr1-1_0431 hypothetical protein\tK19717 ATG33; autophagy-related protein 33"
				}
				]
			}
			]
		},
		{
			"name":"Pexophagy",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"PAS_chr3_1073 Peroxisomal membrane protein (PMP)\tK13336 PEX3; peroxin-3"
				},
				{
					"name":"PAS_chr4_0794 Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery\tK13343 PEX14; peroxin-14"
				}
				]
			},
			{
				"name":"Cargo receptors",
				"children":[
				{
					"name":"PAS_chr3_1230 ATG30\tK22259 ATG30; autophagy-related protein 30"
				}
				]
			},
			{
				"name":"Other pexophagy associated proteins",
				"children":[
				{
					"name":"PAS_chr3_1045 Peroxisome biosynthesis protein PAS1\tK13338 PEX1; peroxin-1 [EC:3.6.4.-]"
				},
				{
					"name":"PAS_chr1-4_0133 AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p\tK13339 PEX6; peroxin-6 [EC:3.6.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"Aggrephagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold proteins"
			},
			{
				"name":"Other aggrephagy associated proteins",
				"children":[
				{
					"name":"PAS_FragD_0026 ATPase in ER, nuclear membrane and cytosol with homology to mammalian P97\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"PAS_chr2-1_0302 Putative catalytic subunit of a class II histone deacetylase complex\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
				}
				]
			}
			]
		},
		{
			"name":"Xenophagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Other xenophagy associated proteins"
			}
			]
		},
		{
			"name":"ER-phagy",
			"children":[
			{
				"name":"ER-phagy recepters",
				"children":[
				{
					"name":"PAS_chr3_1014 Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p)\tK12275 SEC62; translocation protein SEC62"
				}
				]
			},
			{
				"name":"Other ER-phagy associated proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0322 Calnexin\tK08054 CANX; calnexin"
				},
				{
					"name":"PAS_chr4_0396 Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p\tK17278 PGRMC1_2; membrane-associated progesterone receptor component"
				}
				]
			},
			{
				"name":"ER stress-related proteins",
				"children":[
				{
					"name":"PAS_chr2-1_0140 ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding I\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"PAS_chr3_0077 Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start\tK03237 EIF2S1; translation initiation factor 2 subunit 1"
				},
				{
					"name":"PAS_chr2-1_0038 hypothetical protein\tK14009 BCAP31; B-cell receptor-associated protein 31"
				}
				]
			}
			]
		},
		{
			"name":"Chaperone mediated autophagy (CMA)",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"PAS_chr4_0974 hypothetical protein\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
				},
				{
					"name":"PAS_chr2-1_0437 Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"PAS_chr3_0693 Tetrameric phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"PAS_chr3_0826 Tetrameric phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"PAS_chr2-1_0769 Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"PAS_chr2-1_0892 hypothetical protein\tK04523 UBQLN; ubiquilin"
				}
				]
			},
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Chaperones",
				"children":[
				{
					"name":"PAS_chr3_0230 ATPase involved in protein folding and the response to stress\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"PAS_chr3_0731 Cytoplasmic ATPase that is a ribosome-associated molecular chaperone\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"PAS_chr4_0552 ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"PAS_chr1-4_0130 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"Co-chaperones"
			},
			{
				"name":"Other CMA associated proteins",
				"children":[
				{
					"name":"PAS_FragB_0052 Translational elongation factor EF-1 alpha\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"PAS_chr1-4_0013 carboxypeptidase Y\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
				}
				]
			}
			]
		},
		{
			"name":"Other autophagy associated proteins",
			"children":[
			{
				"name":"RNautophagy\/DNautophagy"
			},
			{
				"name":"Micronucleophagy",
				"children":[
				{
					"name":"PAS_chr1-4_0101 Phosphorylated vacuolar membrane protein that interacts with Atg13p\tK08332 VAC8; vacuolar protein 8"
				}
				]
			},
			{
				"name":"Midbophagy"
			},
			{
				"name":"Glycophagy"
			},
			{
				"name":"TRIM-directed selective autophagy"
			},
			{
				"name":"ER-mitochondria tethering complex",
				"children":[
				{
					"name":"PAS_chr2-1_0285 Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenanceof the mitoc\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"mTORC1 complex",
				"children":[
				{
					"name":"PAS_chr2-1_0557 PIK-related protein kinase and rapamycin target\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr2-2_0150 Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"PAS_chr2-1_0459 Subunit of TORC1, a rapamycin-sensitive complex involved in growth control\tK07204 RAPTOR; regulatory associated protein of mTOR"
				}
				]
			},
			{
				"name":"mTORC2 complex",
				"children":[
				{
					"name":"PAS_chr2-1_0557 PIK-related protein kinase and rapamycin target\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"PAS_chr2-2_0150 Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"PAS_chr3_0162 Component of a membrane-bound complex containing the Tor2p kinase and other proteins\tK20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1\/AVO1"
				},
				{
					"name":"PAS_chr4_0955 hypothetical protein\tK08267 RICTOR; rapamycin-insensitive companion of mTOR"
				},
				{
					"name":"PAS_chr2-1_0241 Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regu\tK25576 AVO2; target of rapamycin complex 2 subunit AVO2"
				}
				]
			},
			{
				"name":"SEACIT\/GATOR1 complex",
				"children":[
				{
					"name":"PAS_chr1-3_0181 hypothetical protein\tK20404 DEPDC5; SEA\/GATOR complex protein SEA1\/DEPDC5"
				},
				{
					"name":"PAS_chr4_0159 Protein with a possible role in regulating expression of nitrogen permeases\tK20405 NPRL2; nitrogen permease regulator 2"
				},
				{
					"name":"PAS_chr1-4_0385 Ser\/Thr protein kinase involved in salt tolerance\tK20406 NPRL3; nitrogen permease regulator 3"
				}
				]
			},
			{
				"name":"SEACAT\/GATOR2 complex",
				"children":[
				{
					"name":"PAS_chr1-4_0442 hypothetical protein\tK20408 WDR24; SEA\/GATOR complex protein SEA2\/WDR24"
				},
				{
					"name":"PAS_chr1-3_0222 hypothetical protein\tK20409 WDR59; SEA\/GATOR complex protein SEA3\/WDR59"
				},
				{
					"name":"PAS_chr1-1_0224 Nuclear pore protein that is part of the evolutionarily conserved Nup84p complex\tK14299 SEH1; nucleoporin SEH1"
				},
				{
					"name":"PAS_chr1-3_0057 Component of both the Nup84 nuclear pore sub-complex and of the COPII complex\tK14004 SEC13; protein transport protein SEC13"
				}
				]
			},
			{
				"name":"KICSTOR complex"
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"PAS_chr3_1167 hypothetical protein\tK07874 RAB1A; Ras-related protein Rab-1A"
				},
				{
					"name":"PAS_chr3_0143 Secretory vesicle-associated Rab GTPase essential for exocytosis\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr1-1_0307 Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
				},
				{
					"name":"PAS_chr1-4_0119 Essential protein involved in the TOR signaling pathway\tK17606 IGBP1; immunoglobulin-binding protein 1"
				},
				{
					"name":"PAS_chr2-1_0083 hypothetical protein\tK21249 UVRAG; UV radiation resistance-associated gene protein"
				},
				{
					"name":"PAS_chr1-1_0353 Vacuolar integral membrane protein\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"PAS_chr2-2_0343 Vacuolar transporter, exports large neutral amino acids from the vacuole\tK14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)"
				},
				{
					"name":"PAS_chr3_0295 Vacuolar transporter\tK14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)"
				},
				{
					"name":"PAS_chr1-4_0196 Phosphatidylinositol 3,5-bisphosphate-binding protein\tK22991 WDR45; WD repeat-containing protein 45"
				},
				{
					"name":"PAS_chr1-1_0410 Vacuolar ATPase assembly integral membrane protein VMA21\tK23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21"
				},
				{
					"name":"PAS_chr1-4_0625 hypothetical protein\tK27411 PHAF1; phagosome assembly factor 1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Others",
		"children":[
		{
			"name":"NADPH oxidases (Nox) and associated proteins",
			"children":[
			{
				"name":"NADPH oxidases"
			},
			{
				"name":"Nox associated proteins",
				"children":[
				{
					"name":"PAS_chr1-3_0113 Small rho-like GTPase, essential for establishment and maintenance of cell polarity\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				}
				]
			}
			]
		},
		{
			"name":"Actin-binding proteins",
			"children":[
			{
				"name":"Myosins",
				"children":[
				{
					"name":"PAS_chr4_0618 One of two type I myosins\tK10356 MYO1; myosin I"
				},
				{
					"name":"PAS_FragB_0012 Myosin-2\tK10357 MYO5; myosin V"
				}
				]
			},
			{
				"name":"Arp2\/3 complex",
				"children":[
				{
					"name":"PAS_chr2-2_0328 Subunit of the ARP2\/3 complex\tK05757 ARPC1A_B; actin related protein 2\/3 complex, subunit 1A\/1B"
				},
				{
					"name":"PAS_chr3_1121 Subunit of the ARP2\/3 complex\tK05758 ARPC2; actin related protein 2\/3 complex, subunit 2"
				},
				{
					"name":"PAS_chr3_0238 Subunit of the ARP2\/3 complex\tK05756 ARPC3; actin related protein 2\/3 complex, subunit 3"
				},
				{
					"name":"PAS_chr1-4_0185 Subunit of the ARP2\/3 complex\tK05755 ARPC4; actin related protein 2\/3 complex, subunit 4"
				},
				{
					"name":"PAS_chr2-2_0029 Subunit of the ARP2\/3 complex\tK05754 ARPC5; actin related protein 2\/3 complex, subunit 5"
				},
				{
					"name":"PAS_chr3_0458 Essential component of the Arp2\/3 complex\tK17260 ACTR2; actin-related protein 2"
				},
				{
					"name":"PAS_chr2-1_0556 Essential component of the Arp2\/3 complex\tK18584 ACTR3; actin-related protein 3"
				}
				]
			},
			{
				"name":"Nucleation-promoting factors (NPFs)",
				"children":[
				{
					"name":"PAS_chr1-4_0623 Actin assembly factor, activates the Arp2\/3 protein complex that nucleates branched actin filaments\tK23612 WASL; neural Wiskott-Aldrich syndrome protein"
				},
				{
					"name":"PAS_chr2-2_0320 Actin-binding protein of the cortical actin cytoskeleton\tK20520 DBNL; drebrin-like protein"
				},
				{
					"name":"PAS_chr3_0694 Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"PAS_chr2-1_0116 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p)\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr3_0498 Actin-associated protein\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr3_0983 Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p)\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"PAS_chr2-1_0366 Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"PAS_chr3_1226 hypothetical protein\tK20521 BBC1; myosin tail region-interacting protein MTI1"
				},
				{
					"name":"PAS_chr4_0500 Protein that induces appearance of [PIN+] prion when overproduced\tK20522 LSB1_2; LAS seventeen-binding protein 1\/2"
				},
				{
					"name":"PAS_chr3_0795 Protein involved in the organization of the actin cytoskeleton\tK20523 SH3YL1; SH3 domain-containing YSC84-like protein 1"
				},
				{
					"name":"PAS_chr4_0841 hypothetical protein\tK20524 LSB5; LAS seventeen-binding protein 5"
				},
				{
					"name":"PAS_chr1-4_0143 Type II phosphatidylinositol 4-kinase that binds Las17p\tK13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"PAS_chr3_0106 Profilin, actin-and phosphatidylinositol 4,5-bisphosphate-binding protein, involved in cytoskeleton\tK05759 PFN; profilin"
				},
				{
					"name":"PAS_chr1-4_0027 Cofilin, promotes actin filament depolarization in a pH-dependent manner\tK05765 CFL; cofilin"
				},
				{
					"name":"PAS_chr2-2_0067 CAP (cyclase-associated protein) subunit of adenylyl cyclase complex\tK17261 CAP1_2; adenylyl cyclase-associated protein"
				},
				{
					"name":"PAS_chr3_0589 Component of yeast cortical actin cytoskeleton\tK20526 TAGLN; transgelin"
				}
				]
			}
			]
		},
		{
			"name":"Mucins",
			"children":[
			{
				"name":"Membrane bound mucins"
			},
			{
				"name":"Secretory mucins"
			}
			]
		},
		{
			"name":"MARVEL domain-containing proteins"
		},
		{
			"name":"Specific organelles associated proteins",
			"children":[
			{
				"name":"Melanosome"
			},
			{
				"name":"Auto phagosome"
			},
			{
				"name":"Lipid droplets",
				"children":[
				{
					"name":"PAS_chr2-1_0385 hypothetical protein\tK28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]"
				},
				{
					"name":"PAS_chr2-2_0027 hypothetical protein\tK28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]"
				}
				]
			},
			{
				"name":"Mitochondrion"
			}
			]
		},
		{
			"name":"Rho GTPase associated proteins",
			"children":[
			{
				"name":"Rho GTPase-activating proteins",
				"children":[
				{
					"name":"PAS_chr4_0681 GTPase-activating protein (RhoGAP) for Rho3p and Rho4p\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				}
				]
			},
			{
				"name":"Rho guanine nucleotide exchange factors (GEFs)",
				"children":[
				{
					"name":"PAS_chr2-1_0599 Protein of unknown function with similarity to human DOCK proteins\tK05727 DOCK3; dedicator of cytokinesis protein 3"
				},
				{
					"name":"PAS_chr1-1_0142 hypothetical protein\tK28415 DENND11; DENN domain-containing protein 11"
				}
				]
			}
			]
		}
		]
	}
	]
}