{
	"name":"ppsd03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"87912092 hypothetical protein\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"87904292 PHR1; Deoxyribodipyrimidine photolyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"87905212 UNG1; uracil DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"87904523 thp1; uracil DNA N-glycosylase Thp1\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"87911062 hypothetical protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"87906123 OGG1; 8-oxoguanine glycosylase ogg1\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"87907013 NTH1_1; alpha,alpha-trehalase nth1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"87905381 APN1; DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"87906402 APN2; DNA-(apurinic or apyrimidinic site) lyase 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"87907852 POL3; DNA-directed DNA polymerase delta\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"87907388 cdc1; DNA polymerase delta small subunit Cdc1\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"87911728 hypothetical protein\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"87908780 hypothetical protein\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"87910668 POL2; DNA polymerase epsilon catalytic subunit\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"87906851 DPB2; DNA-directed DNA polymerase epsilon, subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"87905422 POL30; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"87911272 FEN1; Elongation of fatty acids protein 2\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"87913758 cdc17; ATP-dependent DNA ligase Cdc17\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"87906597 uncharacterized protein\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"87912460 HNT3; aprataxin-like protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"87910583 pnk1; DNA kinase\/phosphatase Pnk1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"87902381 uncharacterized protein\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"87910301 hypothetical protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"87911671 hypothetical protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"87913523 RAD23; UV excision repair protein rad23\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"87913627 HRT1; RING-box protein hrt1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"87913305 hypothetical protein\tK10609 CUL4; cullin 4"
						},
						{
							"name":"87911628 hypothetical protein\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"87907917 RAD7; UV-damaged DNA-binding protein rad7\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"87907916 RAD16; DNA repair protein rad16\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"87904558 RPO21; DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"87909533 RPB2; DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"87909143 rpb3; RNA polymerase II subunit 3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"87905741 uncharacterized protein\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"87908590 RPB5; DNA-directed RNA polymerases II 24 kDa polypeptide (RNA polymerase II subunit 5)\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"87913730 RPO26; subunit common to RNA polymerases I, II, and III\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"87905999 RPB7; DNA-directed RNA polymerase II subunit\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"87911814 RPB8; DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"87913142 hypothetical protein\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"87904549 RPB10; DNA-directed RNA polymerase II subunit L\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"87907384 RPB11; DNA-directed RNA polymerase II core subunit\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"87912304 RPC10; DNA-directed RNA polymerase core subunit rpc10\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"87913627 HRT1; RING-box protein hrt1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"87913305 hypothetical protein\tK10609 CUL4; cullin 4"
						},
						{
							"name":"87911628 hypothetical protein\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"87913901 rhp26; DNA repair protein rhp26\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"87907327 uncharacterized protein\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"87913751 SSL2; DNA repair helicase RAD25\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"87912138 RAD3; TFIIH\/NER complex ATP-dependent 5'-3' DNA helicase subunit\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"87912154 TFB1; RNA polymerase II transcription factor B subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"87909090 hypothetical protein\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"87908941 TFB4; RNA polymerase II transcription factor B subunit 4\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"87909772 TFB2; RNA polymerase II transcription factor B 52 kDa subunit\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"87906999 TFB5; TFIIH complex subunit tfb5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"87907398 KIN28; TFIIH complex serine\/threonine-protein kinase subunit kin28\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"87907655 uncharacterized protein\tK06634 CCNH; cyclin H"
					},
					{
						"name":"87905450 TFB3; TFIIH\/NER complex subunit\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"87906912 RFA1; Replication factor A protein 1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"87911899 ssb2; Replication factor A protein 2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"87907320 uncharacterized protein\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"87912759 RAD14; DNA repair protein rad14\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"87910178 RAD10; ssDNA endonuclease and repair protein rad10\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"87906279 rad16; DNA repair protein RAD16\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"87905306 RAD2; DNA repair protein rad2\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"87913758 cdc17; ATP-dependent DNA ligase Cdc17\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"87906007 uncharacterized protein\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"87912155 CIA1; Cytosolic iron-sulfur protein assembly protein\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"87905225 uncharacterized protein\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"87904763 uncharacterized protein\tK03869 CUL3; cullin 3"
					},
					{
						"name":"87912005 ELC1; elongin C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"87905013 uncharacterized protein\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"87911258 msh2; MSH2 protein\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"87905206 MSH3; Mismatch repair protein msh3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"87910711 MSH6; DNA mismatch repair protein msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"87911889 mlh1; DNA mismatch repair protein Mlh1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"87911751 PMS1; ATP-binding mismatch repair protein\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"87909184 MLH3; DNA mismatch repair protein\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"87907852 POL3; DNA-directed DNA polymerase delta\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"87907388 cdc1; DNA polymerase delta small subunit Cdc1\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"87911728 hypothetical protein\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"87908780 hypothetical protein\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"87906912 RFA1; Replication factor A protein 1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"87911899 ssb2; Replication factor A protein 2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"87907320 uncharacterized protein\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"87909109 rfc1; DNA replication factor C complex subunit Rfc1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"87905651 RFC2; Subunit of heteropentameric Replication factor C (RF-C)\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"87907076 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"87908983 RFC5; Replication factor C (RF-C) subunit\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"87909355 RFC3; Subunit of heteropentameric Replication factor C (RF-C)\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"87905422 POL30; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"87911178 EXO1; Rad2 nuclease\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"87913758 cdc17; ATP-dependent DNA ligase Cdc17\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"87910991 hypothetical protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"87912763 MRE11; meiotic recombination\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"87904483 RAD50; DNA repair protein rad50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"87912763 MRE11; meiotic recombination\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"87904483 RAD50; DNA repair protein rad50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"87905683 rhp51; RecA recombinase Rhp51\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"87905683 rhp51; RecA recombinase Rhp51\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"87908980 rhp57; DNA repair protein rhp57\tK10958 RAD57; DNA repair protein RAD57"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"87908047 RAD52; DNA repair protein rad52\tK10873 RAD52; DNA repair and recombination protein RAD52"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"87910961 RAD54; DNA-dependent ATPase protein rad54\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"87905404 SGS1; ATP-dependent DNA helicase sgs1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"87905404 SGS1; ATP-dependent DNA helicase sgs1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"87913684 TOP3; DNA topoisomerase\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"87906912 RFA1; Replication factor A protein 1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"87911899 ssb2; Replication factor A protein 2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"87907320 uncharacterized protein\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"87912181 PSY2; Platinum sensitivity protein\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"87906277 SMC5; Structural maintenance of chromosomes protein 5\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"87910906 smc6; Structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"87906686 uncharacterized protein\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"87910057 hypothetical protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"87906344 uncharacterized protein\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"87908939 hypothetical protein\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"87902362 MUS81; Crossover junction endonuclease mus81\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"87912646 SEM1; 26S proteasome complex subunit\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"87905222 uncharacterized protein\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"87907506 SLX1; Slx4p interacting protein\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"87912058 hypothetical protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"87909130 EAF3; Esa1p-associated factor\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"87910887 hypothetical protein\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"87905331 uncharacterized protein\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"87905568 MPH1; 3'-5' DNA helicase\tK14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"87912216 ATP-dependent DNA helicase II subunit 1\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"87913680 YKU80; ATP-dependent DNA helicase yku80\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"87912763 MRE11; meiotic recombination\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"87904483 RAD50; DNA repair protein rad50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"87913398 LIG4; DNA ligase (ATP)\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"87905317 uncharacterized protein\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					},
					{
						"name":"87907049 uncharacterized protein\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"87912460 HNT3; aprataxin-like protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"87910122 hypothetical protein\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"87909043 hypothetical protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"87907737 MHF1; MHF histone-fold complex component\tK11511 APITD1; centromere protein S"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"87905404 SGS1; ATP-dependent DNA helicase sgs1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"87913684 TOP3; DNA topoisomerase\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					}
					]
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"87906127 uncharacterized protein\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"87905683 rhp51; RecA recombinase Rhp51\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"87905184 TEL2; telomere binding protein\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"87908746 hypothetical protein\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"87911621 hypothetical protein\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"87913713 hypothetical protein\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"87910991 hypothetical protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"87906423 RAD30; DNA-directed DNA polymerase eta rad30\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"87909014 hypothetical protein\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"87910859 hypothetical protein\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"87905355 REV1; deoxycytidyl transferase\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"87906411 REV3; DNA polymerase zeta\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"87911764 UBC2; Ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"87906737 RAD18; E3 ubiquitin-protein ligase rad18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"87912926 RAD5; DNA helicase rad5\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"87908535 hypothetical protein\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"87909952 MMS2; E2 ubiquitin-conjugating protein mms2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"87906348 uncharacterized protein\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"87905422 POL30; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"87903734 hypothetical protein\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"87913373 hypothetical protein\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"87902964 hus1; Checkpoint protein hus1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"87904641 rad1_2; checkpoint clamp complex protein Rad1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"87906206 rad17; RFC checkpoint protein Rad17\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"87905651 RFC2; Subunit of heteropentameric Replication factor C (RF-C)\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"87907076 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"87908983 RFC5; Replication factor C (RF-C) subunit\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"87909355 RFC3; Subunit of heteropentameric Replication factor C (RF-C)\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"87904641 rad1_2; checkpoint clamp complex protein Rad1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"87907297 TOF1; Topoisomerase 1-associated factor 1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"87906529 CSM3; chromosome segregation in meiosis-related protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"87908084 uncharacterized protein\tK11272 MRC1; mediator of replication checkpoint protein 1"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"87905184 TEL2; telomere binding protein\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"87913274 hypothetical protein\tK20403 TTI1; TELO2-interacting protein 1"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"87912169 hypothetical protein\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"87907853 uncharacterized protein\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"87905815 MEC1; serine\/threonine-protein kinase M1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"87913509 TEL1; Serine\/threonine-protein kinase tel1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"87904697 chk1; Chk1 protein kinase\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"87905102 DUN1; serine\/threonine protein kinase\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"87904767 MIH1; m-phase inducer phosphatase\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"87905023 uncharacterized protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"87905105 BMH1; 14-3-3 protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"87908083 SWE1; mitosis inhibitor protein kinase swe1\tK03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]"
				},
				{
					"name":"87913328 FKH2; transcription factor\tK24664 FKH; forkhead protein FKH"
				},
				{
					"name":"87911591 VPS4; Vacuolar protein sorting-associated protein 4\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"87909098 hypothetical protein\tK25059 SDE2; replication stress response regulator SDE2"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"87904768 POL5; DNA-directed DNA polymerase\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"87906131 pso2; DNA cross-link repair protein PSO2\/SNM1\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"87912246 hypothetical protein\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"87906018 uncharacterized protein\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"87908064 uncharacterized protein\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"87912840 hypothetical protein\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"87906690 CEF1; Pre-mRNA-splicing factor cef1\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"87906987 uncharacterized protein\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"87906195 PRP46; pre-mRNA-splicing factor prp46\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"87904422 uncharacterized protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"87905420 DUT1; Deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"87912047 RNR1; ribonucleotide-diphosphate reductase subunit rnr1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"87913866 RNR2; Ribonucleotide-diphosphate reductase (RNR), small subunit\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"87912092 hypothetical protein\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"87904292 PHR1; Deoxyribodipyrimidine photolyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"87905212 UNG1; uracil DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"87908102 MAG1; 3-methyladenine DNA glycosylase\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"87911062 hypothetical protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"87910043 hypothetical protein\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"87907013 NTH1_1; alpha,alpha-trehalase nth1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"87910104 srs2; ATP-dependent DNA helicase srs2\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"87910104 srs2; ATP-dependent DNA helicase srs2\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"87904422 uncharacterized protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"87905420 DUT1; Deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}