{
	"name":"pruf03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"121359087 RNMT; mRNA cap guanine-N7 methyltransferase isoform X1\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"121360529 RNGTT; mRNA-capping enzyme isoform X1\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]"
					},
					{
						"name":"121355434 CDK7; cyclin-dependent kinase 7 isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"121358573 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					},
					{
						"name":"121349014 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]"
					},
					{
						"name":"121354568 RAMAC; RNA guanine-N7 methyltransferase activating subunit isoform X1\tK18708 FAM103A1; RNMT-activating mini protein"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"121363765 NCBP1; nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"121357954 NCBP2; nuclear cap-binding protein subunit 2 isoform X1\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					},
					{
						"name":"121363259 nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"121349017 NUDT21; cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"121352485 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					},
					{
						"name":"121355188 CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"121352357 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"121362269 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"121355974 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"121359130 CPSF3; LOW QUALITY PROTEIN: cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"121350595 CPSF4; cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"121363390 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"121349732 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"121362844 pre-mRNA 3'-end-processing factor FIP1-like isoform X1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"121364039 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"121350011 WDR82; WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"121355156 PPP1CA; serine\/threonine-protein phosphatase PP1-alpha catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"121358769 PPP1CB; serine\/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"121364966 PPP1CC; serine\/threonine-protein phosphatase PP1-gamma catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"121351482 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"121359566 CSTF1; cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"121349117 CSTF2; cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"121350432 CSTF3; cleavage stimulation factor subunit 3 isoform X1\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"121363696 SYMPK; symplekin\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"121359587 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B'\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"121365106 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"121355226 SNRPE; small nuclear ribonucleoprotein E isoform X1\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"121357226 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"121352745 SNRPG; small nuclear ribonucleoprotein G isoform X1\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"121359916 LSM10; U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10"
					},
					{
						"name":"121361428 LSM11; U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11"
					},
					{
						"name":"121355974 CPSF2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"121359130 CPSF3; LOW QUALITY PROTEIN: cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"121349117 CSTF2; cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"121363696 SYMPK; symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"121348544 histone RNA hairpin-binding protein-like\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"121363646 uncharacterized protein LOC121363646\tK18710 SLBP; histone RNA hairpin-binding protein"
					},
					{
						"name":"121360492 CASP8AP2; CASP8-associated protein 2\tK25593 CASP8AP2; CASP8-associated protein 2"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"121362987 SUPT4H1; transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"121353940 METTL14; N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"121359054 METTL4; N(6)-adenine-specific methyltransferase METTL4 isoform X1\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"121351679 METTL16; RNA N6-adenosine-methyltransferase METTL16\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"121354812 pre-mRNA-splicing regulator WTAP\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"121351943 VIRMA; protein virilizer homolog isoform X1\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"121350936 RBM15B; putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"121365464 RBM15; RNA-binding protein 15\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"121353234 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"121357400 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"121357052 PAPOLG; poly(A) polymerase gamma\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"121358191 PAPOLA; poly(A) polymerase alpha isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"121355379 TENT2; poly(A) RNA polymerase GLD2\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]"
					},
					{
						"name":"121354220 speckle targeted PIP5K1A-regulated poly(A) polymerase-like\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"121349605 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"121355626 RBM26; RNA-binding protein 26 isoform X1\tK13192 RBM26; RNA-binding protein 26"
					},
					{
						"name":"121348883 FTO; alpha-ketoglutarate-dependent dioxygenase FTO\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"121350714 ALKBH5; RNA demethylase ALKBH5\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]"
					},
					{
						"name":"121349632 TAR DNA-binding protein 43\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"121361784 DHX40; probable ATP-dependent RNA helicase DHX40 isoform X1\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]"
				},
				{
					"name":"121362319 KIN; DNA\/RNA-binding protein KIN17 isoform X1\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"121362738 DNA\/RNA-binding protein KIN17-like\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"121356601 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 isoform X1\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]"
				},
				{
					"name":"121350882 METTL22; methyltransferase-like protein 22 isoform X1\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"121351242 TENT5B; terminal nucleotidyltransferase 5B\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"121360515 TENT5A; terminal nucleotidyltransferase 5A\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]"
				},
				{
					"name":"121351721 TENT5C; terminal nucleotidyltransferase 5C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"121363158 TENT5D; terminal nucleotidyltransferase 5D\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]"
				},
				{
					"name":"121356016 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X1\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"121362999 RBM8A; RNA-binding protein 8A\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"121361910 MAGOH; protein mago nashi homolog\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"121352792 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"121358760 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"121352341 CCDC174; coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"121351079 CASC3; protein CASC3\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"121364183 SAP18; histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"121356033 PNN; pinin\tK13114 PNN; pinin"
					},
					{
						"name":"121350724 RNPS1; RNA-binding protein with serine-rich domain 1\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"121349940 SRRM1; serine\/arginine repetitive matrix protein 1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"121359091 THOC1; THO complex subunit 1 isoform X1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"121363004 THOC2; THO complex subunit 2 isoform X1\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"121361285 THOC3; THO complex subunit 3\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"121352792 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"121365066 THOC5; THO complex subunit 5 homolog isoform X1\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"121349612 THOC7; THO complex subunit 7 homolog\tK13176 THOC7; THO complex subunit 7"
					},
					{
						"name":"121353515 chromatin target of PRMT1 protein isoform X1\tK28424 CHTOP; chromatin target of PRMT1 protein"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"121352619 PCID2; PCI domain-containing protein 2 isoform X1\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"121355351 ENY2; transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"121362821 CETN2; centrin-2 isoform X1\tK10840 CETN2; centrin-2"
					},
					{
						"name":"121350412 CETN3; centrin-3 isoform X1\tK16466 CETN3; centrin-3"
					},
					{
						"name":"121360467 germinal-center associated nuclear protein isoform X1\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"121360083 TPR; nucleoprotein TPR\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"121359527 RAE1; mRNA export factor\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"121350520 SEC13; protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"121363573 NUP37; nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"121363820 NUP85; nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"121354832 NUP43; nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43"
					},
					{
						"name":"121363559 NUP50; nuclear pore complex protein Nup50 isoform X1\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"121349355 NUP54; nucleoporin p54 isoform X1\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"121363206 NUP62CL; nucleoporin-62 C-terminal-like protein\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"121361787 NUP88; nuclear pore complex protein Nup88\tK14318 NUP88; nuclear pore complex protein Nup88"
					},
					{
						"name":"121348991 NUP93; nuclear pore complex protein Nup93 isoform X1\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"121355124 NUP98; nuclear pore complex protein Nup98-Nup96\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"121352605 NUP107; nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"121354360 NUP133; nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"121357588 NUP188; nucleoporin NUP188\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"121357813 NUP153; nuclear pore complex protein Nup153 isoform X1\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"121356308 NUP155; nuclear pore complex protein Nup155 isoform X1\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"121352320 NUP160; nuclear pore complex protein Nup160\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"121364439 NUP35; nucleoporin NUP35 isoform X1\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"121357248 NUP205; nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"121349070 NUP210; nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"121357517 NUP214; nuclear pore complex protein Nup214 isoform X1\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"121362938 POM121; LOW QUALITY PROTEIN: nuclear envelope pore membrane protein POM 121\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"121364176 NUP58; nucleoporin p58\/p45 isoform X1\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"121353161 NUP42; nucleoporin NUP42\tK14321 NUPL2; nucleoporin-like protein 2"
					},
					{
						"name":"121361997 NDC1; nucleoporin NDC1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"121359044 SEH1L; nucleoporin SEH1 isoform X1\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"121354046 ranBP2-like and GRIP domain-containing protein 3 isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
					},
					{
						"name":"121364026 SENP2; sentrin-specific protease 2\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
					},
					{
						"name":"121356082 AAAS; aladin isoform X1\tK14320 AAAS; aladin"
					},
					{
						"name":"121350412 CETN3; centrin-3 isoform X1\tK16466 CETN3; centrin-3"
					},
					{
						"name":"121357508 GLE1; nucleoporin GLE1 isoform X1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"121363744 nucleoporin GLE1-like\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"121363157 NXT2; NTF2-related export protein 2 isoform X1\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"121364969 RAN; GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"121354391 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"121361446 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B"
					},
					{
						"name":"121352370 ELAVL1; ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"121361969 ELAVL4; ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"121363605 ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"121363709 ELAVL2; ELAV-like protein 2 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"121361281 FAF2; FAS-associated factor 2 isoform X1\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"121354247 transitional endoplasmic reticulum ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"121359113 transitional endoplasmic reticulum ATPase-like\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"121348698 VCPKMT; protein-lysine methyltransferase METTL21D\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]"
					},
					{
						"name":"121356407 transportin-2-like\tK18727 TNPO2; transportin-2"
					},
					{
						"name":"121357026 XPO1; exportin-1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"121365975 XPO7; exportin-7 isoform X1\tK18460 XPO7; exportin-7"
					},
					{
						"name":"121361143 RANGAP1; ran GTPase-activating protein 1 isoform X1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"121361630 TAF15; TATA-binding protein-associated factor 2N isoform X1\tK14651 TAF15; transcription initiation factor TFIID subunit 15"
					},
					{
						"name":"121348844 NUTF2; nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"121353687 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"121361391 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"121362598 EIF4E; eukaryotic translation initiation factor 4E isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"121353729 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"121351333 EIF4G3; eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"121352078 EIF4G2; eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"121353655 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"121358160 EIF4B; eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"121351449 EIF4H; eukaryotic translation initiation factor 4H isoform X1\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"121360057 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 isoform X1\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1"
					},
					{
						"name":"121353889 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2"
					},
					{
						"name":"121364925 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"121355959 ANGEL1; protein angel homolog 1 isoform X1\tK18729 ANGEL; protein angel"
					},
					{
						"name":"121358591 ANGEL2; protein angel homolog 2\tK18729 ANGEL; protein angel"
					},
					{
						"name":"121353809 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"121363062 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"121354161 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"121361343 CYFIP2; cytoplasmic FMR1-interacting protein 2\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"121361406 GEMIN5; gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"121365941 TACC3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"121350247 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121354405 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121357967 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121365632 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121364526 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"121353596 GIGYF2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"121349955 PABPC4; polyadenylate-binding protein 4\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"121355305 PABPC1; polyadenylate-binding protein 1 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"121359713 PABPC1L; polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"121358004 polyadenylate-binding protein-interacting protein 1-like isoform X1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"121365274 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"121355063 PAIP2; polyadenylate-binding protein-interacting protein 2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"121357305 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform X1\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"121363252 MCTS1; malignant T-cell-amplified sequence 1\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"121364958 DENR; density-regulated protein\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex",
					"children":[
					{
						"name":"121349833 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"121349849 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"121358269 A1CF; APOBEC1 complementation factor\tK24978 A1CF; APOBEC1 complementation factor"
					}
					]
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"121356738 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"121361503 DAZAP1; DAZ-associated protein 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"121361622 MSI2; RNA-binding protein Musashi homolog 2 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"121364985 MSI1; RNA-binding protein Musashi homolog 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"121354835 HBS1L; HBS1-like protein isoform X1\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"121365276 PELO; protein pelota homolog\tK06965 PELO; protein pelota"
					},
					{
						"name":"121362838 PABPN1L; embryonic polyadenylate-binding protein 2 isoform X1\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"121351368 ATP-dependent RNA helicase DDX19B\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"121360628 DDX25; ATP-dependent RNA helicase DDX25\tK18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]"
					},
					{
						"name":"121365659 XAB2; pre-mRNA-splicing factor SYF1\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"121359429 SAP domain-containing ribonucleoprotein\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"121351234 RCC1; regulator of chromosome condensation isoform X1\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"121354396 LARP6; la-related protein 6 isoform X1\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"121360707 la-related protein 6-like\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"121364610 PURA; transcriptional activator protein Pur-alpha\tK21772 PURA; transcriptional activator protein Pur-alpha"
					},
					{
						"name":"121359889 PURB; transcriptional activator protein Pur-beta\tK21799 PURB; transcriptional activator protein Pur-beta"
					},
					{
						"name":"121361180 POLDIP3; polymerase delta-interacting protein 3 isoform X1\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"121355225 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform X1\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"121354522 PATL2; LOW QUALITY PROTEIN: protein PAT1 homolog 2\tK24823 PATL2; protein PAT1 homolog 2"
					},
					{
						"name":"121353751 FYTTD1; UAP56-interacting factor isoform X1\tK28772 FYTTD1; UAP56-interacting factor"
					},
					{
						"name":"121363101 UAP56-interacting factor-like isoform X1\tK28772 FYTTD1; UAP56-interacting factor"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"121354974 ETF1; eukaryotic peptide chain release factor subunit 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"121350605 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"121352701 UPF1; regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"121362317 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"121354158 regulator of nonsense transcripts 3A-like\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"121363059 UPF3B; regulator of nonsense transcripts 3B isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"121349153 PPP2CB; serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"121361303 PPP2CA; serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"121362083 PPP2R1A; serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"121350080 PPP2R2D; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"121360962 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"121365611 PPP2R2B; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"121365978 PPP2R2A; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"121354087 PPP2R3B; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"121356020 PPP2R3C; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"121363992 PPP2R3A; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"121353919 PPP2R5D; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"121358212 PPP2R5E; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"121358224 PPP2R5C; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"121358567 PPP2R5A; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"121350669 SMG1; serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"121352164 SMG5; protein SMG5 isoform X1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"121361582 SMG6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"121360081 SMG7; protein SMG7 isoform X1\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"121361785 SMG8; protein SMG8 isoform X1\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"121364656 SMG9; protein SMG9\tK18735 SMG9; protein SMG9"
					},
					{
						"name":"121353596 GIGYF2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"121354328 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"121363956 SECISBP2; selenocysteine insertion sequence-binding protein 2\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"121361078 GTPBP1; GTP-binding protein 1 isoform X1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"121363681 PUM3; pumilio homolog 3\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"121350393 MYO5B; unconventional myosin-Vb\tK10357 MYO5; myosin V"
					},
					{
						"name":"121354389 MYO5C; unconventional myosin-Vc\tK10357 MYO5; myosin V"
					},
					{
						"name":"121354445 MYO5A; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"121353405 BICD2; protein bicaudal D homolog 2 isoform X1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"121364333 protein bicaudal D homolog 1 isoform X1\tK18739 BICD; protein bicaudal D"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"121350746 ACTB; actin, cytoplasmic 1\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"121363408 ACTG1; actin, cytoplasmic 2\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"121365545 actin, cytoplasmic type 5\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"121362915 myelin basic protein isoform X1\tK17269 MBP; myelin basic protein"
					},
					{
						"name":"121365744 VIM; vimentin\tK07606 VIM; vimentin"
					},
					{
						"name":"121349001 metallothionein-1\tK14739 MT1_2; metallothionein 1\/2"
					},
					{
						"name":"121364668 MYC; myc proto-oncogene protein\tK04377 MYC; Myc proto-oncogene protein"
					},
					{
						"name":"121352672 GDF1; embryonic growth\/differentiation factor 1\tK05495 GDF1; growth differentiation factor 1"
					},
					{
						"name":"121364990 T-box-containing protein TBX6L\tK10180 TBX6; T-box protein 6"
					},
					{
						"name":"121350195 NANOS1; nanos homolog 1\tK18741 NANOS1; protein nanos 1"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"121357529 FUBP3; far upstream element-binding protein 3 isoform X1\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"121362042 FUBP1; far upstream element-binding protein 1 isoform X1\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"121358850 EEF1A1; elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"121359446 EEF1A2; elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"121355025 EEF1G; elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"121353193 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2\/B1 isoform X1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1"
					},
					{
						"name":"121352189 HAX1; HCLS1-associated protein X-1\tK16220 HAX1; HCLS1-associated protein X-1"
					},
					{
						"name":"121357968 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"121352018 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"121359485 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"121353144 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3"
					},
					{
						"name":"121360679 PTBP1; polypyrimidine tract-binding protein 1 isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"121350247 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121354405 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121357967 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121365632 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"121353809 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"121363062 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"121354161 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"121361343 CYFIP2; cytoplasmic FMR1-interacting protein 2\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"121356077 PCBP2; poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"121351147 PCBP4; poly(rC)-binding protein 4\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"121355896 PCBP3; poly(rC)-binding protein 3 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"121361977 poly(rC)-binding protein 3-like isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"121349096 CAPRIN1; caprin-1 isoform X1\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"121353390 CAPRIN2; caprin-2\tK18744 CAPRIN2; caprin-2"
					},
					{
						"name":"121365798 YBX1; Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"121357923 XRN1; 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"121359884 AGO2; protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"121359886 AGO3; protein argonaute-3 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"121359931 protein argonaute-4 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"121359933 protein argonaute-1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"121353687 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"121361391 EIF4E1B; eukaryotic translation initiation factor 4E type 1B\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"121362598 EIF4E; eukaryotic translation initiation factor 4E isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"121352701 UPF1; regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"121364526 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"121348481 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"121349305 RNA-binding E3 ubiquitin-protein ligase MEX3C-like\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"121352169 MEX3A; LOW QUALITY PROTEIN: RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"121354493 MEX3B; RNA-binding protein MEX3B isoform X1\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"121361495 RNA-binding E3 ubiquitin-protein ligase MEX3C-like\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"121355532 FASTK; fas-activated serine\/threonine kinase\tK08290 FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]"
					},
					{
						"name":"121359492 LSM14B; protein LSM14 homolog B isoform X1\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"121365940 LSM14A; protein LSM14 homolog A isoform X1\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"121356077 PCBP2; poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2"
					},
					{
						"name":"121365798 YBX1; Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"121352960 LIMD1; LIM domain-containing protein 1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"121365938 Wilms tumor protein 1-interacting protein isoform X1\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"121349833 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"121349849 C->U-editing enzyme APOBEC-1-like\tK16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]"
					},
					{
						"name":"121353246 MOV10; helicase MOV-10\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"121349981 PNRC2; proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2"
					},
					{
						"name":"121357899 LOW QUALITY PROTEIN: transportin-1-like\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"121363626 TNPO1; transportin-1\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"121350669 SMG1; serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"121352164 SMG5; protein SMG5 isoform X1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"121361582 SMG6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"121360081 SMG7; protein SMG7 isoform X1\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"121349508 ZFP36L1; mRNA decay activator protein ZFP36L1\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"121358831 ZFP36L2; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"121351240 LIN28A; protein lin-28 homolog A\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"121359291 LIN28B; protein lin-28 homolog B isoform X1\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"121364108 HTT; huntingtin\tK04533 HD; huntingtin"
					},
					{
						"name":"121353382 IPO8; importin-8 isoform X1\tK18755 IPO8; importin-8"
					},
					{
						"name":"121357594 BICC1; protein bicaudal C homolog 1 isoform X1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"121356738 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"121361926 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"121361449 LARP1; la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"121361528 LARP1B; la-related protein 1B isoform X1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"121364967 ATXN2; ataxin-2 isoform X1\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"121355543 DCP2; m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"121351589 DCP1A; mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"121362734 DCP1B; mRNA-decapping enzyme 1B\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"121359146 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"121352472 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"121352675 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"121349038 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"121365243 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"121354664 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"121355822 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X1\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"121357351 KLC4; kinesin light chain 4 isoform X1\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"121358213 KLC1; kinesin light chain 1 isoform X1\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"121350393 MYO5B; unconventional myosin-Vb\tK10357 MYO5; myosin V"
					},
					{
						"name":"121354389 MYO5C; unconventional myosin-Vc\tK10357 MYO5; myosin V"
					},
					{
						"name":"121354445 MYO5A; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"121353470 tubulin alpha-1B chain-like\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"121353700 tubulin alpha-3 chain-like isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"121355708 tubulin alpha-3 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"121356789 tubulin alpha-5 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"121357467 tubulin alpha-1A chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"121362665 TUBA8; tubulin alpha-8 chain isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"121365437 tubulin alpha-8 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"121350247 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121354405 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121357967 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121365632 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"121361406 GEMIN5; gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"121365941 TACC3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3"
					},
					{
						"name":"121361067 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"121363802 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"121365815 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"121348777 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"121352537 CNOT2; CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"121357220 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"121349311 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"121361312 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"121360286 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"121361426 CNOT8; CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"121365939 GARRE1; granule associated Rac and RHOG effector protein 1\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1"
					},
					{
						"name":"121353780 DIS3L2; DIS3-like exonuclease 2\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"121358951 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"121364150 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"121351298 protein BTG1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121355742 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121357180 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121361093 TOB2; protein Tob2 isoform X1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121362373 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121363841 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121364925 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"121355194 PATL1; protein PAT1 homolog 1 isoform X1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"121365484 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"121348819 EDC4; enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"121360546 nanos homolog 3-like\tK18761 NANOS3; protein nanos 3"
					},
					{
						"name":"121362317 UPF2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"121354158 regulator of nonsense transcripts 3A-like\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"121363059 UPF3B; regulator of nonsense transcripts 3B isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"121353122 TRIM71; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"121360155 POLR2G; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"121358740 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]"
					},
					{
						"name":"121348543 ZAR1; zygote arrest protein 1\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"121364261 ZAR1L; LOW QUALITY PROTEIN: ZAR1-like protein\tK18762 ZAR1; zygote arrest protein 1"
					},
					{
						"name":"121356908 YTHDF3; YTH domain-containing family protein 3 isoform X1\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"121359471 YTHDF1; YTH domain-containing family protein 1 isoform X1\tK20102 YTHDF; YTH domain-containing family protein"
					},
					{
						"name":"121359940 YTHDF2; YTH domain-containing family protein 2\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"121350041 TIAL1; nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"121352746 TIA1; nucleolysin TIA-1 isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"121349955 PABPC4; polyadenylate-binding protein 4\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"121355305 PABPC1; polyadenylate-binding protein 1 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"121359713 PABPC1L; polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"121352018 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"121359485 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"121353809 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"121363062 FMR1; synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"121352370 ELAVL1; ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1"
					},
					{
						"name":"121361375 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"121349318 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"121353671 EIF2A; eukaryotic translation initiation factor 2A isoform X1\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"121350859 EIF3B; eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"121353729 EIF4A2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"121358760 EIF4A3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"121358160 EIF4B; eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"121351333 EIF4G3; eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"121352078 EIF4G2; eukaryotic translation initiation factor 4 gamma 2\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"121353655 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"121349805 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"121351243 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"121356155 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"121363044 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"121357539 TRAF2; TNF receptor-associated factor 2 isoform X1\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
					},
					{
						"name":"121353233 TDRD3; tudor domain-containing protein 3\tK18404 TDRD3; tudor domain-containing protein 3"
					},
					{
						"name":"121353958 LARP4; la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4"
					},
					{
						"name":"121363885 LARP4B; la-related protein 4B isoform X1\tK18763 LARP4; la-related protein 4"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"121351589 DCP1A; mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]"
					},
					{
						"name":"121362734 DCP1B; mRNA-decapping enzyme 1B\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"121355543 DCP2; m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"121348481 DDX6; probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"121365484 EDC3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"121348819 EDC4; enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"121355194 PATL1; protein PAT1 homolog 1 isoform X1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"121359146 LSM1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"121352472 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"121352675 LSM4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"121349038 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"121365243 LSM6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"121354664 LSM7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"121355822 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X1\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"121357923 XRN1; 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"121357041 XRN2; 5'-3' exoribonuclease 2\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"121360569 DCPS; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"121363367 HELZ; probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"121350024 EXOSC1; exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"121357641 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"121357522 EXOSC3; exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"121351294 EXOSC5; exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"121348789 EXOSC6; LOW QUALITY PROTEIN: exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"121353179 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"121353242 EXOSC8; exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"121361544 EXOSC9; exosome complex component RRP45\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"121355628 DIS3; exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"121354422 DIS3L; DIS3-like exonuclease 1 isoform X1\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"121351422 EXOSC10; exosome component 10 isoform X1\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"121358651 C1D; nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"121348892 MPHOSPH6; M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"121348918 TENT4B; terminal nucleotidyltransferase 4B\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"121358091 TENT4A; terminal nucleotidyltransferase 4A isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"121351315 ZCCHC7; zinc finger CCHC domain-containing protein 7\tK12597 AIR1_2; protein AIR1\/2"
					},
					{
						"name":"121355314 MTREX; exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"121365367 TTC37; tetratricopeptide repeat protein 37 isoform X1\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"121365481 WDR61; WD repeat-containing protein 61 isoform X1\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"121349311 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"121361312 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"121348777 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"121352537 CNOT2; CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"121357220 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"121360286 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"121361426 CNOT8; CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"121356583 CNOT9; CCR4-NOT transcription complex subunit 9 isoform X1\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"121352936 CNOT10; CCR4-NOT transcription complex subunit 10 isoform X1\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"121358951 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"121364150 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"121350910 PARN; poly(A)-specific ribonuclease PARN isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"121354913 PNLDC1; poly(A)-specific ribonuclease PNLDC1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"121353680 DHX36; ATP-dependent DNA\/RNA helicase DHX36\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"121351298 protein BTG1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121355742 BTG4; protein BTG4\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121357180 BTG1; protein BTG1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121361093 TOB2; protein Tob2 isoform X1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121362373 BTG2; protein BTG2\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121363841 TOB1; protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"121354684 NOCT; nocturnin\tK18764 NOCT; nocturnin [EC:3.1.3.108]"
					},
					{
						"name":"121360263 ERI1; 3'-5' exoribonuclease 1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"121350633 ERI2; ERI1 exoribonuclease 2\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]"
					},
					{
						"name":"121360569 DCPS; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"121351940 PDE12; 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"121365486 IREB2; iron-responsive element-binding protein 2 isoform X1\tK22416 IREB2; iron-responsive element-binding protein 2"
					},
					{
						"name":"121363367 HELZ; probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"121348562 HELZ2; helicase with zinc finger domain 2 isoform X1\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]"
					},
					{
						"name":"121356055 NRDE2; nuclear exosome regulator NRDE2\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"121358365 SAMD4A; protein Smaug homolog 1 isoform X1\tK27396 SMG; protein Smaug"
					},
					{
						"name":"121363344 FOCAD; focadhesin isoform X1\tK27498 FOCAD; focadhesin"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases",
					"children":[
					{
						"name":"121354821 ZC3H12D; probable ribonuclease ZC3H12D\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"121359908 ZC3H12A; endoribonuclease ZC3H12A\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"121363029 ZC3H12B; probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					},
					{
						"name":"121364173 ZC3H12C; probable ribonuclease ZC3H12C\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"121358062 DROSHA; ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"121348515 REXO2; oligoribonuclease, mitochondrial\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"121349624 ENO1; alpha-enolase isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"121351571 ENO2; gamma-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"121357137 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"121356079 PFKM; ATP-dependent 6-phosphofructokinase, muscle type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"121363988 PFKL; ATP-dependent 6-phosphofructokinase, liver type isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"121365631 ATP-dependent 6-phosphofructokinase, platelet type isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"121354964 HSPA9; stress-70 protein, mitochondrial\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"121356405 HSPD1; 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"121357641 EXOSC2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"121350024 EXOSC1; exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"121353179 EXOSC7; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}