{
	"name":"psb03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"Psyr_3951 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases",
				"children":[
				{
					"name":"Psyr_0650 Protein of unknown function RIO1\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"Psyr_0564 Exonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"Psyr_3950 Small GTP-binding protein domain:GTP-binding:GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Psyr_0703 GTP-binding protein, HSR1-related:GTP1\/OBG subdomain protein\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"Psyr_0835 transcriptional regulator, TraR\/DksA family\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"Psyr_3262 dnaK suppressor protein, putative\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"Psyr_4181 Transcription termination factor NusA:Transcription termination factor NusA, C-terminal duplication\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"Psyr_4458 Antitermination protein NusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"Psyr_4560 transcription antitermination protein nusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"Psyr_3981 ribosomal small subunit pseudouridine synthase A\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"Psyr_4627 dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"Psyr_0017 16S rRNA m(5)C-967 methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"Psyr_0986 16S rRNA m(2)G 1207 methyltransferase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"Psyr_4754 16S rRNA m(2)G-966 methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"Psyr_0453 16S rRNA m(3)U-1498 methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Psyr_5131 16S rRNA m(7)G-527 methyltransferase\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Psyr_4110 methyltransferase\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"Psyr_4112 Protein of unknown function UPF0011\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Psyr_1325 Protein of unknown function DUF548\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"Psyr_1330 23S rRNA m(1)G-745 methyltransferase\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"Psyr_0580 23S rRNA Gm-2251 2'-O-methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"Psyr_4188 23S rRNA Um-2552 2'-O-methyltransferase\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"Psyr_1085 23S rRNA m(6)A-1618 methyltransferase\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"Psyr_4279 16S rRNA m(2)G 1207 methyltransferase \/ 23S rRNA m(2)G-1835 methyltransferase\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]"
				},
				{
					"name":"Psyr_4366 Protein of unknown function DUF163\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"Psyr_2337 conserved hypothetical protein\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Psyr_4172 conserved hypothetical protein\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Psyr_4764 SAM-dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Psyr_4772 Protein of unknown function DUF519\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"Psyr_2108 23S rRNA m(2)G-2445 methyltransferase\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"Psyr_3403 conserved hypothetical protein\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"Psyr_1245 23S rRNA m(2)A-2503 methyltransferase\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"Psyr_3696 23S rRNA m(5)U-1939 methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"Psyr_1610 ribosomal large subunit pseudouridine synthase A\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"Psyr_2133 Pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"Psyr_3581 ribosomal large subunit pseudouridine synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"Psyr_1639 ribosomal large subunit pseudouridine synthase C\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"Psyr_0726 ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Psyr_4336 ribosomal large subunit pseudouridine synthase E\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"Psyr_1390 RNA-binding S4\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"Psyr_0857 [SSU ribosomal protein S18P]-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"Psyr_0173 SSU ribosomal protein S6P modification protein\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"Psyr_1283 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"Psyr_1392 SSU ribosomal protein S12P methylthiotransferase\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"Psyr_4402 [LSU ribosomal protein L11P]-lysine N-methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"Psyr_1850 [LSU ribosomal protein L3P]-glutamine N5-methyltransferase\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"Psyr_3193 Transcription factor jumonji, jmjC\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"Psyr_3951 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"Psyr_1638 RNAse E\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"Psyr_4159 RNAse G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"Psyr_0484 Conserved hypothetical protein 250\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"Psyr_0516 ATP-dependent RNA helicase DbpA\tK05591 dbpA; ATP-dependent RNA helicase DbpA [EC:5.6.2.6]"
			},
			{
				"name":"Psyr_3619 Helicase, C-terminal:DbpA, RNA-binding:DEAD\/DEAH box helicase, N-terminal\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"Psyr_3791 Helicase, C-terminal:DEAD\/DEAH box helicase, N-terminal\tK05590 srmB; ATP-dependent RNA helicase SrmB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"Psyr_3950 Small GTP-binding protein domain:GTP-binding:GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"Psyr_0563 Protein of unknown function DUF258\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"Psyr_1252 Small GTP-binding protein protein domain:GTP-binding protein\tK03977 engA; GTPase"
			},
			{
				"name":"Psyr_0703 GTP-binding protein, HSR1-related:GTP1\/OBG subdomain protein\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"Psyr_0573 GTP-binding protein HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"Psyr_0022 translation factor SUA5\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"Psyr_0209 RelA\/SpoT protein\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"Psyr_4179 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"Psyr_4182 Protein of unknown function DUF150\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"Psyr_4367 Iojap-related protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"Psyr_4347 Protein of unknown function UPF0054\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"Psyr_4189 Protein of unknown function UPF0044\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"Psyr_4155 Protein of unknown function DUF615\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"Psyr_2107 Ribosome modulation factor\tK03812 rmf; ribosome modulation factor"
			},
			{
				"name":"Psyr_4148 sigma 54 modulation protein \/ SSU ribosomal protein S30P\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"Psyr_0941 Conserved hypothetical protein 92\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"Psyr_1643 Protein of unknown function DUF177\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}