{
	"name":"psco03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"LY89DRAFT_654100 methylated-DNA--cysteine S-met\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"LY89DRAFT_679953 uncharacterized protein\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"LY89DRAFT_679568 uncharacterized protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"LY89DRAFT_605421 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"LY89DRAFT_565894 DNA glycosylase\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"LY89DRAFT_776252 N-glycosylase\/DNA lyase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"LY89DRAFT_684322 DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"LY89DRAFT_696138 apurinic\/apyrimidinic endonuclease-like protein\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"LY89DRAFT_691728 DNase I-like protein\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"LY89DRAFT_740574 uncharacterized protein\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"LY89DRAFT_619491 DNA polymerase-like protein subunit delta-2\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"LY89DRAFT_790120 uncharacterized protein\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"LY89DRAFT_679938 uncharacterized protein\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"LY89DRAFT_787183 DUF1744-domain-containing protein\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"LY89DRAFT_782999 uncharacterized protein\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"LY89DRAFT_610518 histone-fold-containing protein\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"LY89DRAFT_607274 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"LY89DRAFT_686547 flap endonuclease-like protein 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"LY89DRAFT_493340 DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"LY89DRAFT_585461 tyrosyl-DNA phosphodiesterase\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"LY89DRAFT_721198 phospholipase D\/nuclease\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"LY89DRAFT_656717 HIT-like protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"LY89DRAFT_653805 PNK3P-domain-containing protein\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"LY89DRAFT_707348 PARP-domain-containing protein\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"LY89DRAFT_204884 Rad4-domain-containing protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"LY89DRAFT_685449 Rad4-domain-containing protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"LY89DRAFT_623137 UV excision repair protein Rad23\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"LY89DRAFT_688943 E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"LY89DRAFT_597120 Cullin-domain-containing protein\tK10609 CUL4; cullin 4"
						},
						{
							"name":"LY89DRAFT_646785 uncharacterized protein\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"LY89DRAFT_352368 DNA repair protein-like protein Rad7\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"LY89DRAFT_711924 uncharacterized protein\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"LY89DRAFT_16699 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"LY89DRAFT_683984 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"LY89DRAFT_155990 RNA polymerase II subunit 3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"LY89DRAFT_595077 uncharacterized protein\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"LY89DRAFT_616916 RPB5 subunit of DNA-directed RNA polymerase\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"LY89DRAFT_681554 RNA polymerase Rpb6\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"LY89DRAFT_599800 uncharacterized protein\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"LY89DRAFT_661535 DNA-directed RNA polymerases and 3 polypeptide\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"LY89DRAFT_683074 DNA-directed RNA polymerase-like protein II subunit rpb9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"LY89DRAFT_604672 putative DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"LY89DRAFT_686261 RBP11-like subunits of RNA polymerase\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"LY89DRAFT_345210 DNA directed RNA polymerase\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"LY89DRAFT_688943 E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"LY89DRAFT_597120 Cullin-domain-containing protein\tK10609 CUL4; cullin 4"
						},
						{
							"name":"LY89DRAFT_646785 uncharacterized protein\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"LY89DRAFT_688371 WD40 repeat-like protein\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"LY89DRAFT_682766 uncharacterized protein\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"LY89DRAFT_682830 Elf1-domain-containing protein\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"LY89DRAFT_718388 DNA repair helicase rad25\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"LY89DRAFT_703743 DNA repair helicase\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"LY89DRAFT_750435 uncharacterized protein\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"LY89DRAFT_629844 TFIIH basal transcription factor complex, subunit SSL1\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"LY89DRAFT_652593 transcription factor Tfb4\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"LY89DRAFT_452072 transcription factor Tfb2\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"LY89DRAFT_684331 RNA polymerase II transcription factor B subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"LY89DRAFT_588514 Pkinase-domain-containing protein\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"LY89DRAFT_681523 cyclin-like protein\tK06634 CCNH; cyclin H"
					},
					{
						"name":"LY89DRAFT_690016 RNA polymerase II transcription factor-like protein B subunit 3\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"LY89DRAFT_688416 replication factor-a protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"LY89DRAFT_782492 replication protein A, subunit RPA32\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"LY89DRAFT_391103 replication factor A protein 3\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"LY89DRAFT_540787 DNA repair protein\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"LY89DRAFT_640555 uncharacterized protein\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"LY89DRAFT_777280 DNA repair protein\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"LY89DRAFT_683768 PIN domain-like protein\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"LY89DRAFT_493340 DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"LY89DRAFT_689026 uncharacterized protein\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"LY89DRAFT_688560 putative cytosolic iron-sulfur protein assembly protein 1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"LY89DRAFT_692911 uncharacterized protein\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"LY89DRAFT_613538 Cullin-domain-containing protein\tK03869 CUL3; cullin 3"
					},
					{
						"name":"LY89DRAFT_663595 putative Elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"LY89DRAFT_549259 uncharacterized protein\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"LY89DRAFT_787089 DNA mismatch repair protein msh-2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"LY89DRAFT_636859 DNA mismatch repair protein msh3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"LY89DRAFT_643546 DNA mismatch repair protein Msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"LY89DRAFT_631908 DNA mismatch repair protein MutL\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"LY89DRAFT_678911 DNA mismatch repair protein MutL\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"LY89DRAFT_743715 uncharacterized protein\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"LY89DRAFT_740574 uncharacterized protein\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"LY89DRAFT_619491 DNA polymerase-like protein subunit delta-2\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"LY89DRAFT_790120 uncharacterized protein\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"LY89DRAFT_679938 uncharacterized protein\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"LY89DRAFT_688416 replication factor-a protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"LY89DRAFT_782492 replication protein A, subunit RPA32\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"LY89DRAFT_391103 replication factor A protein 3\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"LY89DRAFT_684333 DNA replication factor C, large subunit\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"LY89DRAFT_611996 P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"LY89DRAFT_679259 P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"LY89DRAFT_721343 P-loop containing nucleoside triphosphate hydrolase protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"LY89DRAFT_788408 P-loop containing nucleoside triphosphate hydrolase protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"LY89DRAFT_607274 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"LY89DRAFT_619648 uncharacterized protein\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"LY89DRAFT_493340 DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"LY89DRAFT_588902 WD40 repeat-like protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"LY89DRAFT_605531 DNA repair exonuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"LY89DRAFT_706435 uncharacterized protein\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"LY89DRAFT_605531 DNA repair exonuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"LY89DRAFT_706435 uncharacterized protein\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex"
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"LY89DRAFT_788877 P-loop containing nucleoside triphosphate hydrolase protein\tK10958 RAD57; DNA repair protein RAD57"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"LY89DRAFT_624575 uncharacterized protein\tK10873 RAD52; DNA repair and recombination protein RAD52"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"LY89DRAFT_689317 uncharacterized protein\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"LY89DRAFT_609528 uncharacterized protein\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"LY89DRAFT_607616 uncharacterized protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"LY89DRAFT_607616 uncharacterized protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"LY89DRAFT_421355 DNA topoisomerase-like protein III\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"LY89DRAFT_563204 uncharacterized protein\tK15364 NCE4; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"LY89DRAFT_688416 replication factor-a protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"LY89DRAFT_782492 replication protein A, subunit RPA32\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"LY89DRAFT_391103 replication factor A protein 3\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"LY89DRAFT_137694 DUF625-domain-containing protein\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"LY89DRAFT_713948 P-loop containing nucleoside triphosphate hydrolase protein\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"LY89DRAFT_595663 putative structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"LY89DRAFT_660755 uncharacterized protein\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"LY89DRAFT_652687 uncharacterized protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"LY89DRAFT_726623 Nse4-domain-containing protein\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"LY89DRAFT_727761 uncharacterized protein\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"LY89DRAFT_691372 uncharacterized protein\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"LY89DRAFT_695016 uncharacterized protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"LY89DRAFT_788713 uncharacterized protein\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"LY89DRAFT_584753 uncharacterized protein\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"LY89DRAFT_621328 PIN domain-like protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"LY89DRAFT_783633 uncharacterized protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"LY89DRAFT_122575 AAA-domain-containing protein\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"LY89DRAFT_727386 WLM-domain-containing protein\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"LY89DRAFT_777398 WLM-domain-containing protein\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"LY89DRAFT_607135 P-loop containing nucleoside triphosphate hydrolase protein\tK14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"LY89DRAFT_620587 ku70 protein\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"LY89DRAFT_715267 SPOC domain-like protein\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"LY89DRAFT_605531 DNA repair exonuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"LY89DRAFT_638376 ATP-dependent DNA ligase\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"LY89DRAFT_602043 Nucleotidyltransferase\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					},
					{
						"name":"LY89DRAFT_695003 DNA polymerase lambda\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"LY89DRAFT_656717 HIT-like protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"LY89DRAFT_764166 uncharacterized protein\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"LY89DRAFT_539743 uncharacterized protein\tK11511 APITD1; centromere protein S"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"LY89DRAFT_607616 uncharacterized protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"LY89DRAFT_421355 DNA topoisomerase-like protein III\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"LY89DRAFT_563204 uncharacterized protein\tK15364 NCE4; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"LY89DRAFT_633896 uncharacterized protein\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"LY89DRAFT_292418 uncharacterized protein\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"LY89DRAFT_703753 WD repeat protein-like protein\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"LY89DRAFT_669779 uncharacterized protein\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"LY89DRAFT_346824 uncharacterized protein\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"LY89DRAFT_687879 WD40 repeat-like protein\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"LY89DRAFT_588902 WD40 repeat-like protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"LY89DRAFT_281011 DNA\/RNA polymerase\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"LY89DRAFT_781330 DNA\/RNA polymerase\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"LY89DRAFT_643298 impB\/mucB\/samB family protein\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"LY89DRAFT_714252 DNA repair protein\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"LY89DRAFT_789805 uncharacterized protein\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"LY89DRAFT_685126 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"LY89DRAFT_790119 DNA repair protein rad18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"LY89DRAFT_608615 putative DNA repair protein rad-5\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"LY89DRAFT_782638 putative SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"LY89DRAFT_705497 UBC-like protein\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"LY89DRAFT_713764 ubiquitin-conjugating enzyme E2\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"LY89DRAFT_607274 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"LY89DRAFT_649201 uncharacterized protein\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"LY89DRAFT_233184 Rad9-domain-containing protein\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"LY89DRAFT_716527 cell cycle checkpoint protein-like protein\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"LY89DRAFT_326242 Rad1-domain-containing protein\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"LY89DRAFT_701849 Rad17-domain-containing protein\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"LY89DRAFT_611996 P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"LY89DRAFT_679259 P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"LY89DRAFT_721343 P-loop containing nucleoside triphosphate hydrolase protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"LY89DRAFT_788408 P-loop containing nucleoside triphosphate hydrolase protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"LY89DRAFT_326242 Rad1-domain-containing protein\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"LY89DRAFT_641737 timeless-domain-containing protein\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"LY89DRAFT_657627 Swi3-domain-containing protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"LY89DRAFT_647814 uncharacterized protein\tK11272 MRC1; mediator of replication checkpoint protein 1"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"LY89DRAFT_292418 uncharacterized protein\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"LY89DRAFT_642001 uncharacterized protein\tK20403 TTI1; TELO2-interacting protein 1"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"LY89DRAFT_598710 uncharacterized protein\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"LY89DRAFT_716448 DUF410-domain-containing protein\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"LY89DRAFT_598327 protein kinase-like protein rad3\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"LY89DRAFT_266352 phosphatidylinositol 3\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"LY89DRAFT_703354 serine\/threonine-protein kinase-like protein chk1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"LY89DRAFT_714214 Pkinase-domain-containing protein\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"LY89DRAFT_582573 Rhodanese-like protein\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"LY89DRAFT_311691 14-3-3 protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"LY89DRAFT_664392 14-3-3 protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"LY89DRAFT_587047 kinase-like protein\tK03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]"
				},
				{
					"name":"LY89DRAFT_729804 uncharacterized protein\tK24664 FKH; forkhead protein FKH"
				},
				{
					"name":"LY89DRAFT_588754 vacuolar protein sorting-associated protein-like protein VPS4\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"LY89DRAFT_589105 AAA-domain-containing protein\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"LY89DRAFT_684185 uncharacterized protein\tK25059 SDE2; replication stress response regulator SDE2"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"LY89DRAFT_706332 uncharacterized protein\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"LY89DRAFT_722955 DRMBL-domain-containing protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"LY89DRAFT_646003 uncharacterized protein\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"LY89DRAFT_617209 S1\/P1 nuclease-like protein\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"LY89DRAFT_692244 S1\/P1 nuclease\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"LY89DRAFT_673684 uncharacterized protein\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"LY89DRAFT_715041 Prp19-domain-containing protein\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"LY89DRAFT_617319 uncharacterized protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"LY89DRAFT_647590 uncharacterized protein\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"LY89DRAFT_730614 WD40 repeat-like protein\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"LY89DRAFT_574655 putative Deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"LY89DRAFT_692414 uncharacterized protein\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"LY89DRAFT_608592 uncharacterized protein\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"LY89DRAFT_654100 methylated-DNA--cysteine S-met\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"LY89DRAFT_679953 uncharacterized protein\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"LY89DRAFT_679568 uncharacterized protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"LY89DRAFT_605421 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"LY89DRAFT_688485 HhH-GPD superfamily base excision DNA repair protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"LY89DRAFT_652724 putative formamidopyrimidine-DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"LY89DRAFT_684322 DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"LY89DRAFT_682311 P-loop containing nucleoside triphosphate hydrolase protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"LY89DRAFT_682311 P-loop containing nucleoside triphosphate hydrolase protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"LY89DRAFT_574655 putative Deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}