{
	"name":"psk04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"U771_10125 heat shock protein 90\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"U771_07605 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"U771_08960 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"U771_25740 gapA; glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"U771_29525 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"U771_09945 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"U771_25660 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"U771_23615 peptidyl-prolyl cis-trans isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
			},
			{
				"name":"U771_29340 peptidase M19\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"U771_06925 peroxidase\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"U771_16585 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_25845 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_27185 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"U771_27050 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"U771_18480 gluconolactonase\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
			},
			{
				"name":"U771_26185 inosine 5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"U771_28560 tuf; elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"U771_20380 diadenosine tetraphosphatehydrolase\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			},
			{
				"name":"U771_28725 HIT family hydrolase\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells"
		},
		{
			"name":"Exosomal proteins of hepatic cells",
			"children":[
			{
				"name":"U771_19615 membrane protein\tK14347 SLC10A7; solute carrier family 10 (sodium\/bile acid cotransporter), member 7"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"U771_10190 AMP-binding acetyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"U771_18795 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"U771_25090 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"U771_25105 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"U771_16585 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_25845 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_03610 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"U771_11180 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"U771_11785 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"U771_15815 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"U771_18800 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"U771_24240 3-ketoacyl-CoA thiolase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"U771_29600 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"U771_07360 adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"U771_23775 adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"U771_24815 argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"U771_30680 argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"U771_06945 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"U771_18065 cystathionine beta-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
			},
			{
				"name":"U771_20785 phenylhydantoinase\tK01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]"
			},
			{
				"name":"U771_06305 fumarylacetoacetase\tK01555 FAH; fumarylacetoacetase [EC:3.7.1.2]"
			},
			{
				"name":"U771_02115 fructose-1 6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
			},
			{
				"name":"U771_14645 glycogen branching protein\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
			},
			{
				"name":"U771_06880 glpK; glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"U771_19545 glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"U771_02080 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"U771_08695 glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"U771_11240 glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"U771_12080 glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"U771_19350 glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"U771_30250 glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"U771_30255 glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"U771_27050 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"U771_11120 delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"U771_30565 delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"U771_15660 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"U771_23215 phhB; pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"U771_30155 3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"U771_03485 IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"U771_10190 AMP-binding acetyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"U771_18795 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"U771_25090 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"U771_25105 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"U771_10085 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"U771_21025 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"U771_16095 electron transfer flavoprotein subunit beta\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"U771_24315 electron transfer flavoprotein subunit beta\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"U771_18335 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"U771_25145 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"U771_26185 inosine 5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"U771_27185 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"U771_16585 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_25845 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_28560 tuf; elongation factor Tu\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"U771_16585 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_25845 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_27050 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"U771_18335 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"U771_25145 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"U771_27185 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"U771_27125 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"U771_28560 tuf; elongation factor Tu\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"U771_16585 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_25845 groEL; molecular chaperone GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"U771_18335 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"U771_25145 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"U771_27125 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"U771_27125 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells",
			"children":[
			{
				"name":"U771_02125 lipocalin\tK03098 APOD; apolipoprotein D and lipocalin family protein"
			}
			]
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}