{
	"name":"psm03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"PSM_A2335 rnc; RNase III, ds RNA\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases",
				"children":[
				{
					"name":"PSM_B0305 putative kinase\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"PSM_A0378 orn; oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"PSM_A2334 era; GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"PSM_A2691 obgE; GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"PSM_A1831 putative DksA-type zinc finger protein\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"PSM_A2454 dksAA; RNA polymerase factor\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"PSM_A1066 nusA; transcription elongation factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"PSM_A0706 nusB; transcription termination factor\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"PSM_A0232 nusG; transcription antitermination factor\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"PSM_A0090 putative ribosomal RNA pseudouridylate synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"PSM_A0358 rsuA; 16S rRNA pseudouridylate 516 synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"PSM_A2670 ksgA; dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"PSM_A0024 rsmB; 16S rRNA methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"PSM_A2737 N-6 adenine-specific DNA methylase domain-containing protein\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"PSM_A2576 hypothetical protein\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"PSM_A1288 yebU; rRNA (cytosine-C(5)-)-methyltransferase RsmF\tK11392 rsmF; 16S rRNA (cytosine1407-C5)-methyltransferase [EC:2.1.1.178]"
				},
				{
					"name":"PSM_A3117 gidB; glucose-inhibited division protein B\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"PSM_A0493 mraW; S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"PSM_A0484 methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"PSM_A0421 hypothetical protein\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"PSM_A1361 putative 23S rRNA m1G745 methyltransferase\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"PSM_A0535 rlmB; 23S rRNA (guanosine-2'-O-)-methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"PSM_A2176 rrmJ; 23S rRNA methyltransferase J\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"PSM_B0367 putative SAM-dependent methyltransferase\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"PSM_A0841 rsmD; ribosomal RNA small subunit methyltransferase D\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]"
				},
				{
					"name":"PSM_A1999 SPOUT methyltransferase superfamily protein\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"PSM_A1876 yccW; methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"PSM_A1917 hypothetical protein\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"PSM_A2795 hypothetical protein\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"PSM_A1639 23S rRNA m(2)G2445 methyltransferase\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"PSM_A1960 ygdE; putative RNA 2'-O-ribose methyltransferase\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"PSM_B0177 hypothetical protein\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"PSM_A2330 23S rRNA (uracil-5)-methyltransferase, responsible for modification at position U1939, SAM-dependent\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"PSM_A1629 23S rRNA pseudouridylate synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"PSM_A1821 23S rRNA pseudouridylate synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"PSM_A2662 rluA; pseudouridylate synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"PSM_B0287 ribosomal large subunit pseudouridine synthase A (pseudouridylate synthase, 23S RNA-specific)\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"PSM_A1367 rluB; pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"PSM_A1244 rluC; 23S rRNA pseudouridylate synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"PSM_A1006 rluD; 23S rRNA pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"PSM_A1660 ribosomal large subunit pseudouridine synthase E\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"PSM_B0517 putative ribosomal RNA pseudouridine synthase\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"PSM_A2408 rimI; ribosomal-protein-alanine acetyltransferase (acetylating enzyme for N-terminal of ribosomal protein S18)\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"PSM_A2558 rimK; ribosomal protein S6 modification protein\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"PSM_A1016 rimM; 16S rRNA processing protein\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"PSM_A0079 hypothetical protein\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor"
			},
			{
				"name":"PSM_A2742 prmA; 50S ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"PSM_A1046 prmB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"PSM_A1665 RmlC-like domain-containing protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"PSM_A2335 rnc; RNase III, ds RNA\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"PSM_A1243 RNase E: endoribonuclease for rRNA processing and mRNA degradation; member of the degradosome; involved in the production of\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"PSM_A0335 rng; ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"PSM_A2579 Holliday junction resolvase-like protein\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"PSM_A0117 dbpA; ATP-dependent RNA helicase DbpA\tK05591 dbpA; ATP-dependent RNA helicase DbpA [EC:5.6.2.6]"
			},
			{
				"name":"PSM_A1057 deaD; ATP-dependent RNA helicase, cold shock protein A\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"PSM_A2535 srmB; ATP-dependent RNA helicase SrmB\tK05590 srmB; ATP-dependent RNA helicase SrmB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"PSM_A2334 era; GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"PSM_A0377 ribosome-associated GTPase\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"PSM_B0169 engA; GTP-binding protein EngA\tK03977 engA; GTPase"
			},
			{
				"name":"PSM_A2691 obgE; GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"PSM_A3054 rbgA; ribosomal biogenesis GTPase\tK14540 rbgA; ribosome biogenesis GTPase A"
			},
			{
				"name":"PSM_A2819 hflX; protease GTPase subunit\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"PSM_A0032 double-stranded RNA-binding protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"PSM_B0157 putative translation factor\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"PSM_A2860 spoT; bifunctional: (p)ppGpp synthetase II; guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"PSM_A1068 ribosome-binding factor A, role in processing of 16S rRNA\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"PSM_A1065 hypothetical protein\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"PSM_A0174 conserved hypothetical protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"PSM_A1998 hypothetical protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"PSM_A1982 hypothetical protein\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"PSM_A2177 yhbY; RNA binding protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"PSM_A0277 ABC transporter ATP-binding protein\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"PSM_A1521 rmf; ribosome modulation factor\tK03812 rmf; ribosome modulation factor"
			},
			{
				"name":"PSM_A0399 hypothetical protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"PSM_A2390 ribosomal subunit interface protein, protein Y\tK05809 raiA; ribosome-associated inhibitor A"
			},
			{
				"name":"PSM_A1977 engD; translation-associated GTPase\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"PSM_A1247 hypothetical protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}
