{
	"name":"ptet03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"122347473 orc1; origin recognition complex subunit 1 isoform X1\tK02603 ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"122354146 orc2; origin recognition complex subunit 2\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"122361467 orc3; origin recognition complex subunit 3\tK02605 ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"122333276 orc4; origin recognition complex subunit 4\tK02606 ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"122343268 orc5; origin recognition complex subunit 5 isoform X1\tK02607 ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"122349275 orc6; origin recognition complex subunit 6 isoform X1\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"122349541 cdt1; DNA replication factor Cdt1 isoform X1\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"122354555 cdc6; cell division control protein 6 homolog\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"122327312 mcm2; DNA replication licensing factor MCM2\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"122325021 mcm3; DNA replication licensing factor MCM3\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"122325168 mcm3l; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"122329632 LOW QUALITY PROTEIN: DNA replication licensing factor mcm4-B-like\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"122330174 mcm4; LOW QUALITY PROTEIN: DNA replication licensing factor MCM4\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"122341367 mcm5; LOW QUALITY PROTEIN: DNA replication licensing factor MCM5\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"122342038 DNA replication licensing factor mcm5\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"122346428 mcm6; DNA replication licensing factor MCM6\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"122362865 mcm6l; MCM6 minichromosome maintenance deficient 6, like\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"122333628 mcm7; DNA replication licensing factor MCM7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"122352527 ccna1; cyclin-A1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"122357219 ccna2; cyclin-A2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"122323559 G1\/S-specific cyclin-E2-like\tK06626 CCNE; G1\/S-specific cyclin-E1"
				},
				{
					"name":"122348930 ccne1; G1\/S-specific cyclin-E1\tK06626 CCNE; G1\/S-specific cyclin-E1"
				},
				{
					"name":"122360005 ccne2; G1\/S-specific cyclin-E2 isoform X1\tK06626 CCNE; G1\/S-specific cyclin-E1"
				},
				{
					"name":"122354685 cdk2; cyclin-dependent kinase 2\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"122326652 cdc7; cell division cycle 7-related protein kinase isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				},
				{
					"name":"122355203 dbf4b; uncharacterized protein dbf4b isoform X1\tK06629 DBF4; protein DBF4"
				},
				{
					"name":"122360477 dbf4; protein DBF4 homolog A\tK06629 DBF4; protein DBF4"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"122356944 gins1; DNA replication complex GINS protein PSF1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"122362893 gins2; DNA replication complex GINS protein PSF2\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"122330466 gins3; DNA replication complex GINS protein PSF3\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"122349976 gins4; DNA replication complex GINS protein SLD5 isoform X1\tK10735 GINS4; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"122332271 topbp1; DNA topoisomerase 2-binding protein 1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"122323297 recql4; ATP-dependent DNA helicase Q4\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"122350062 cdc45; cell division control protein 45 homolog\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"122334404 mcm8; LOW QUALITY PROTEIN: DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"122324340 mcm9; DNA helicase MCM9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"122342895 mcm10; protein MCM10 homolog isoform X1\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"122356541 mini-chromosome maintenance complex-binding protein isoform X1\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				},
				{
					"name":"122343503 helb; DNA helicase B\tK15254 HELB; DNA helicase B [EC:5.6.2.3]"
				},
				{
					"name":"122345225 serine protease FAM111A-like\tK24274 FAM111A; protein FAM111A"
				},
				{
					"name":"122345226 serine protease FAM111A-like\tK24274 FAM111A; protein FAM111A"
				},
				{
					"name":"122345227 serine protease FAM111A-like\tK24274 FAM111A; protein FAM111A"
				},
				{
					"name":"122346175 serine protease FAM111A-like\tK24274 FAM111A; protein FAM111A"
				},
				{
					"name":"122361484 cyclin-dependent kinase 2-interacting protein-like isoform X1\tK26052 CINP; cyclin-dependent kinase 2-interacting protein"
				},
				{
					"name":"122361802 cyclin-dependent kinase 2-interacting protein isoform X1\tK26052 CINP; cyclin-dependent kinase 2-interacting protein"
				},
				{
					"name":"122362358 cyclin-dependent kinase 2-interacting protein-like\tK26052 CINP; cyclin-dependent kinase 2-interacting protein"
				},
				{
					"name":"122361014 mdm2-binding protein isoform X1\tK26116 MTBP; Mdm2-binding protein"
				},
				{
					"name":"122330296 ticrr; treslin isoform X1\tK26117 TICRR; Treslin"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"122330097 pola1; DNA polymerase alpha catalytic subunit\tK02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"122350301 pola2; DNA polymerase alpha subunit B\tK02321 POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"122328510 prim1; DNA primase small subunit\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"122357129 prim2; DNA primase large subunit\tK02685 PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"122346023 pole; DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"122334458 pole2; DNA polymerase epsilon subunit 2\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"122345151 pole3; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"122335700 pold1; DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"122349951 pold2; LOW QUALITY PROTEIN: DNA polymerase delta subunit 2\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"122350065 DNA polymerase delta subunit 2-like\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"122326082 pold3; DNA polymerase delta subunit 3\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"122345276 pold4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)",
				"children":[
				{
					"name":"122330935 polg; DNA polymerase subunit gamma-1\tK02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]"
				},
				{
					"name":"122346363 polg2; DNA polymerase subunit gamma-2, mitochondrial isoform X1\tK02333 POLG2; DNA polymerase gamma 2"
				}
				]
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"122359351 rpa1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"122359835 rpa2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"122323942 rpa3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"122348287 rfc1; replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"122326773 rfc2; replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"122353594 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"122354022 rfc4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"122345584 rfc5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"122352953 rfc3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"122324512 ribonuclease H1-like\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"122325493 ribonuclease H1-like\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"122341502 rnaseh2a; ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"122351942 rnaseh2b; ribonuclease H2 subunit B isoform X1\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"122357628 rnaseh2c; ribonuclease H2 subunit C\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"122352863 pcna; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"122331004 pclaf; PCNA-associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"122356676 dna2; DNA replication ATP-dependent helicase\/nuclease DNA2\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"122329864 fen1; flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"122356969 zgc:110269; probable flap endonuclease 1 homolog\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"122362153 exo1; exonuclease 1 isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"122327193 zranb3; DNA annealing helicase and endonuclease ZRANB3 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"122328041 lig1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"122338670 atad5a; LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 5\tK26118 ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"122341705 dnmt1; DNA (cytosine-5)-methyltransferase 1 isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"122324927 dnmt3aa; LOW QUALITY PROTEIN: DNA (cytosine-5-)-methyltransferase 3 alpha a\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				},
				{
					"name":"122361901 dnmt3ab; DNA (cytosine-5)-methyltransferase 3A isoform X1\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				},
				{
					"name":"122328809 dnmt3bb.2; DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2 isoform X1\tK17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]"
				},
				{
					"name":"122328810 dnmt3bb.1; DNA (cytosine-5)-methyltransferase 3B isoform X1\tK17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]"
				},
				{
					"name":"122350701 dnmt3ba; DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a\tK17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"122323851 gmnn; geminin\tK10749 GMNN; geminin"
				},
				{
					"name":"122352790 multicilin\tK26119 MCIDAS; multicilin"
				},
				{
					"name":"122335717 G2\/mitotic-specific cyclin-B1-like\tK05868 CCNB1; G2\/mitotic-specific cyclin-B1"
				},
				{
					"name":"122345540 ccnb1; G2\/mitotic-specific cyclin-B1 isoform X1\tK05868 CCNB1; G2\/mitotic-specific cyclin-B1"
				},
				{
					"name":"122362742 G2\/mitotic-specific cyclin-B1-like\tK05868 CCNB1; G2\/mitotic-specific cyclin-B1"
				},
				{
					"name":"122362954 LOW QUALITY PROTEIN: G2\/mitotic-specific cyclin-B1-like\tK05868 CCNB1; G2\/mitotic-specific cyclin-B1"
				},
				{
					"name":"122348316 ccnb2; G2\/mitotic-specific cyclin-B2\tK21770 CCNB2; G2\/mitotic-specific cyclin-B2"
				},
				{
					"name":"122348194 ccnb3; G2\/mitotic-specific cyclin-B3 isoform X1\tK21771 CCNB3; G2\/mitotic-specific cyclin-B3"
				},
				{
					"name":"122362287 cdk1; cyclin-dependent kinase 1\tK02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex",
					"children":[
					{
						"name":"122331174 pot1; protection of telomeres protein 1 isoform X1\tK11109 POT1; protection of telomeres protein 1"
					},
					{
						"name":"122330254 terf1; telomeric repeat-binding factor 1\tK11110 TERF1; telomeric repeat-binding factor 1"
					},
					{
						"name":"122342338 LOW QUALITY PROTEIN: telomeric repeat-binding factor 2-like\tK11111 TERF2; telomeric repeat-binding factor 2"
					},
					{
						"name":"122343030 terfa; telomeric repeat binding factor a\tK11111 TERF2; telomeric repeat-binding factor 2"
					},
					{
						"name":"122349466 tinf2; TERF1-interacting nuclear factor 2 isoform X1\tK11112 TINF2; TERF1-interacting nuclear factor 2"
					},
					{
						"name":"122334034 telomeric repeat-binding factor 2-interacting protein 1\tK11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1"
					},
					{
						"name":"122348600 acd; adrenocortical dysplasia protein homolog isoform X1\tK11114 ACD; adrenocortical dysplasia protein"
					}
					]
				},
				{
					"name":"TERB1-TERB2-MAJIN complex",
					"children":[
					{
						"name":"122363023 terb1; telomere repeats-binding bouquet formation protein 1\tK25749 TERB1; telomere repeats-binding bouquet formation protein 1"
					},
					{
						"name":"122347848 terb2; telomere repeats-binding bouquet formation protein 2 isoform X1\tK25750 TERB2; telomere repeats-binding bouquet formation protein 2"
					},
					{
						"name":"122349649 membrane-anchored junction protein\tK25751 MAJIN; membrane-anchored junction protein"
					}
					]
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"122334570 ctc1; CST complex subunit CTC1\tK23311 CTC1; CST complex subunit CTC1"
					},
					{
						"name":"122348655 stn1; CST complex subunit STN1 isoform X1\tK23312 STN1; CST complex subunit STN1"
					},
					{
						"name":"122346906 ten1; CST complex subunit TEN1 isoform X1\tK23313 TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)"
				},
				{
					"name":"RIF proteins"
				},
				{
					"name":"SIR proteins"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"122352653 smg6; telomerase-binding protein EST1A\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
				},
				{
					"name":"122360499 smg5; protein SMG5 isoform X1\tK11125 SMG5; protein SMG5"
				},
				{
					"name":"122335211 tert; telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"122357951 LOW QUALITY PROTEIN: telomerase protein component 1-like\tK11127 TEP1; telomerase protein component 1"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"122357576 gar1; H\/ACA ribonucleoprotein complex subunit 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"122326462 nhp2; H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"122348621 nop10; H\/ACA ribonucleoprotein complex subunit 3\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"122326401 H\/ACA ribonucleoprotein complex subunit DKC1-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"122326907 LOW QUALITY PROTEIN: H\/ACA ribonucleoprotein complex subunit DKC1-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"122335211 tert; telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"122334287 snrpb; small nuclear ribonucleoprotein-associated proteins B and B'\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"122335165 snrpd1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"122362541 snrpd2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"122326664 snrpd3l; small nuclear ribonucleoprotein D3 polypeptide, like\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"122350316 snrpd3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"122353656 snrpe; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"122349361 snrpf; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"122329237 snrpg; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"122326773 rfc2; replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"122353594 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"122354022 rfc4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"122345584 rfc5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"122352953 rfc3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"122358552 mre11a; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"122326753 rad50; DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"122360755 nbn; nibrin\tK10867 NBN; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"122359125 atm; serine-protein kinase ATM isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"122353167 Werner syndrome ATP-dependent helicase homolog isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
				},
				{
					"name":"122322980 blm; Bloom syndrome protein homolog isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"122348579 prkdc; DNA-dependent protein kinase catalytic subunit\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
				},
				{
					"name":"122355289 DNA repair endonuclease XPF-like\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"122355366 ercc4; DNA repair endonuclease XPF\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"122325426 parp1; poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"122355109 parp2; poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"122326511 tnksa; poly [ADP-ribose] polymerase tankyrase-1\tK10799 TNKS; tankyrase [EC:2.4.2.30]"
				},
				{
					"name":"122345876 tnksb; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b isoform X1\tK10799 TNKS; tankyrase [EC:2.4.2.30]"
				},
				{
					"name":"122355750 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase tankyrase-2-like\tK10799 TNKS; tankyrase [EC:2.4.2.30]"
				},
				{
					"name":"122325448 pinx1; PIN2\/TERF1-interacting telomerase inhibitor 1\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"122353588 rtel1; regulator of telomere elongation helicase 1\tK11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"122329637 telo2; telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"122341593 trir; telomerase RNA component interacting RNase\tK01149 TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]"
				},
				{
					"name":"122351644 rif1; telomere-associated protein RIF1\tK11138 RIF1; telomere-associated protein RIF1"
				},
				{
					"name":"122328497 pif1; ATP-dependent DNA helicase PIF1\tK15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]"
				},
				{
					"name":"122326063 puraa; purine-rich element binding protein Aa\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"122357757 purab; transcriptional activator protein Pur-alpha\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"122353168 purg; purine-rich element-binding protein gamma\tK21800 PURG; purine-rich element-binding protein gamma"
				},
				{
					"name":"122349465 wrap53; telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"122327874 sde2; replication stress response regulator SDE2\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"122347416 rtf2; replication termination factor 2\tK25186 RTF2; replication termination factor 2"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"122328827 top1b; DNA topoisomerase 1 isoform X1\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"122329797 top1mt; DNA topoisomerase I, mitochondrial isoform X1\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"122354512 top1a; DNA topoisomerase I, like\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"122362593 zgc:173742; LOW QUALITY PROTEIN: DNA topoisomerase I, mitochondrial\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"122323811 top2b; DNA topoisomerase 2-beta isoform X1\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"122355630 top2a; DNA topoisomerase 2-alpha\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"122336322 top3a; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"122344670 top3b; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"122342493 ssbp1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)"
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"RNase H",
					"children":[
					{
						"name":"122324512 ribonuclease H1-like\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
					},
					{
						"name":"122325493 ribonuclease H1-like\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
					}
					]
				},
				{
					"name":"Other elongation factors"
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases"
				},
				{
					"name":"D-family DNA polymerases"
				},
				{
					"name":"RNase H",
					"children":[
					{
						"name":"122324512 ribonuclease H1-like\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
					},
					{
						"name":"122325493 ribonuclease H1-like\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
					}
					]
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"122356676 dna2; DNA replication ATP-dependent helicase\/nuclease DNA2\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"122329864 fen1; flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"122356969 zgc:110269; probable flap endonuclease 1 homolog\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"122328041 lig1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein"
			},
			{
				"name":"DNA methylation enzymes"
			},
			{
				"name":"Prevention of re-replication factors"
			}
			]
		},
		{
			"name":"DNA Topoisomerases"
		}
		]
	}
	]
}