{
	"name":"pvo01001",
	"children":[
	{
		"name":"Serine\/threonine kinases: AGC group",
		"children":[
		{
			"name":"PKA family"
		},
		{
			"name":"PKG family"
		},
		{
			"name":"PKC family [OT]"
		},
		{
			"name":"PKN family"
		},
		{
			"name":"AUR family [OT]"
		},
		{
			"name":"PDK1 family"
		},
		{
			"name":"AKT\/PKB family"
		},
		{
			"name":"SGK family [OT]"
		},
		{
			"name":"RSK family [OT]"
		},
		{
			"name":"NDR family"
		},
		{
			"name":"MAST family [OT]"
		},
		{
			"name":"YANK family"
		},
		{
			"name":"DMPK family [OT]"
		},
		{
			"name":"GRK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CAMK group",
		"children":[
		{
			"name":"CAMK1 family [OT]"
		},
		{
			"name":"CAMK2 family"
		},
		{
			"name":"CAMKL family"
		},
		{
			"name":"DAPK family"
		},
		{
			"name":"DCAMKL family"
		},
		{
			"name":"MAPKAPK family [OT]"
		},
		{
			"name":"MLCK family"
		},
		{
			"name":"PHK family"
		},
		{
			"name":"PIM family [OT]"
		},
		{
			"name":"PKD family"
		},
		{
			"name":"PSK family"
		},
		{
			"name":"RAD53 family"
		},
		{
			"name":"Trio family [OT]"
		},
		{
			"name":"TSSK family"
		},
		{
			"name":"CDPK family"
		},
		{
			"name":"CASK family"
		},
		{
			"name":"Trbl family"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CK1 group",
		"children":[
		{
			"name":"CK1 family [OT]"
		},
		{
			"name":"TTBK family"
		},
		{
			"name":"VRK family"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CMGC group",
		"children":[
		{
			"name":"CDK family"
		},
		{
			"name":"MAPK family [OT]"
		},
		{
			"name":"GSK family [OT]"
		},
		{
			"name":"CLK family"
		},
		{
			"name":"CDKL family"
		},
		{
			"name":"DYRK family [OT]"
		},
		{
			"name":"RCK family [OT]"
		},
		{
			"name":"SRPK family [OT]"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: STE group",
		"children":[
		{
			"name":"STE7 family"
		},
		{
			"name":"STE20 family"
		},
		{
			"name":"STE11 family"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: TKL group",
		"children":[
		{
			"name":"IRAK family"
		},
		{
			"name":"LISK family [OT]"
		},
		{
			"name":"LRRK family"
		},
		{
			"name":"MLK family"
		},
		{
			"name":"RAF family [OT]"
		},
		{
			"name":"RIPK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: Other",
		"children":[
		{
			"name":"RGC family [OT]"
		},
		{
			"name":"BUB family"
		},
		{
			"name":"Bud32 family"
		},
		{
			"name":"CAMKK family"
		},
		{
			"name":"CDC7 family"
		},
		{
			"name":"CK2 family"
		},
		{
			"name":"Haspin family"
		},
		{
			"name":"IKK family [OT]"
		},
		{
			"name":"IRE family"
		},
		{
			"name":"MOS family"
		},
		{
			"name":"NAK family [OT]"
		},
		{
			"name":"NEK family"
		},
		{
			"name":"NKF1 family"
		},
		{
			"name":"NKF2 family"
		},
		{
			"name":"NKF3 family"
		},
		{
			"name":"NKF4 family"
		},
		{
			"name":"NKF5 family"
		},
		{
			"name":"NRBP family"
		},
		{
			"name":"PEK family [OT]"
		},
		{
			"name":"PLK family [OT]"
		},
		{
			"name":"SCY1 family [OT]"
		},
		{
			"name":"Slob family"
		},
		{
			"name":"TBCK family"
		},
		{
			"name":"TLK family"
		},
		{
			"name":"TOPK family"
		},
		{
			"name":"TTK family"
		},
		{
			"name":"ULK family [OT]"
		},
		{
			"name":"VPS15 family"
		},
		{
			"name":"WEE family"
		},
		{
			"name":"Wnk family"
		},
		{
			"name":"ABC1 family"
		},
		{
			"name":"Alpha family [OT]"
		},
		{
			"name":"BCR family"
		},
		{
			"name":"BRD family [OT]"
		},
		{
			"name":"FAST family"
		},
		{
			"name":"G11 family"
		},
		{
			"name":"H11 family"
		},
		{
			"name":"PDHK family [OT]"
		},
		{
			"name":"PIKK family [OT]"
		},
		{
			"name":"RIO family [OT]"
		},
		{
			"name":"TAF1 family"
		},
		{
			"name":"TIF1 family [OT]"
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial family",
			"children":[
			{
				"name":"PVOR_12205 serine\/threonine protein kinase with PASTA sensor(s)\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"PVOR_14494 serine\/threonine protein kinase\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"PVOR_29998 putative anti-sigma regulatory factor, serine\/threonine protein kinase\tK04757 rsbW; serine\/threonine-protein kinase RsbW [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Receptor serine\/threonine kinases (RSTK): TKL group",
		"children":[
		{
			"name":"TGFBR1 family [OT]"
		},
		{
			"name":"TGFBR2 family [OT]"
		}
		]
	},
	{
		"name":"Receptor tyrosine kinases (RTK)",
		"children":[
		{
			"name":"EGFR family [OT]"
		},
		{
			"name":"INSR family [OT]"
		},
		{
			"name":"PDGFR family [OT]"
		},
		{
			"name":"FGFR family [OT]"
		},
		{
			"name":"VEGFR family [OT]"
		},
		{
			"name":"MET family"
		},
		{
			"name":"TRK family [OT]"
		},
		{
			"name":"EPH family [OT]"
		},
		{
			"name":"AXL family"
		},
		{
			"name":"ALK family"
		},
		{
			"name":"TIE family"
		},
		{
			"name":"ROR family"
		},
		{
			"name":"DDR family"
		},
		{
			"name":"RET family"
		},
		{
			"name":"ROS family"
		},
		{
			"name":"CCK family"
		},
		{
			"name":"RYK family"
		},
		{
			"name":"MUSK family"
		},
		{
			"name":"LMR family [OT]"
		}
		]
	},
	{
		"name":"Non-receptor tyrosine kinases",
		"children":[
		{
			"name":"ABL family"
		},
		{
			"name":"ACK family"
		},
		{
			"name":"CSK family"
		},
		{
			"name":"FAK family"
		},
		{
			"name":"FES family"
		},
		{
			"name":"JAK family [OT]"
		},
		{
			"name":"SRC family"
		},
		{
			"name":"TEC family"
		},
		{
			"name":"SYK family"
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial",
			"children":[
			{
				"name":"PVOR_28924 capsular exopolysaccharide family protein\tK00903 epsB; protein-tyrosine kinase [EC:2.7.10.3]"
			}
			]
		}
		]
	},
	{
		"name":"Histidine kinases",
		"children":[
		{
			"name":"OmpR family",
			"children":[
			{
				"name":"PVOR_03160 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_24159 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_26428 multi-sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_13359 multi-sensor signal transduction histidine kinase\tK07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_01735 multi-sensor signal transduction histidine kinase\tK07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_01045 integral membrane sensor signal transduction histidine kinase\tK11629 bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06335 integral membrane sensor signal transduction histidine kinase\tK11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06940 integral membrane sensor signal transduction histidine kinase\tK11633 yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06355 integral membrane sensor signal transduction histidine kinase\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_27320 integral membrane sensor signal transduction histidine kinase\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NarL family",
			"children":[
			{
				"name":"PVOR_08910 PAS\/PAC sensor signal transduction histidine kinase\tK07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_31854 Histidine kinase\tK07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_03105 sensor histidine kinase\tK07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_03695 integral membrane sensor signal transduction histidine kinase\tK07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_08245 integral membrane sensor signal transduction histidine kinase\tK07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_20244 integral membrane sensor signal transduction histidine kinase\tK07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_27340 integral membrane sensor signal transduction histidine kinase\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_29749 integral membrane sensor signal transduction histidine kinase\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Spo family [OT]",
			"children":[
			{
				"name":"PVOR_18639 PAS\/PAC sensor signal transduction histidine kinase\tK02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_08870 integral membrane sensor signal transduction histidine kinase\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_09150 integral membrane sensor signal transduction histidine kinase\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_09155 integral membrane sensor signal transduction histidine kinase\tK07697 kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_30393 PAS\/PAC sensor signal transduction histidine kinase\tK07698 kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"CitB family [OT]",
			"children":[
			{
				"name":"PVOR_30833 sensory histidine kinase DcuS\tK11614 yufL; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_02980 sensor histidine kinase\tK02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"LytTR family [OT]",
			"children":[
			{
				"name":"PVOR_00625 signal transduction histidine kinase, LytS\tK07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_20264 two-component sensor histidine kinase\tK07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NtrC family"
		},
		{
			"name":"CheA family [OT]",
			"children":[
			{
				"name":"PVOR_21934 multi-sensor hybrid histidine kinase\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Cell cycle family [OT]"
		},
		{
			"name":"Lux family [OT]"
		},
		{
			"name":"LuxR family [OT]"
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"PVOR_00725 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_04573 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_04653 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_04708 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_05033 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_05850 putative sensor with HAMP domain protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06080 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06435 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06700 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06765 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06795 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_06895 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_07110 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_08075 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_09000 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_09420 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_09505 hypothetical protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_10454 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_11670 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_12825 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_18124 putative sensor with HAMP domain\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_18494 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_23549 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_23959 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_25693 two-component sensor histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_26263 histidine kinase internal region\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_27290 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_30313 putative sensor with HAMP domain protein\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_30358 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_30848 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_32256 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"PVOR_03740 signal transduction histidine kinase, LytS\tK19694 chiS; two-component system, sensor histidine kinase ChiS"
			}
			]
		}
		]
	}
	]
}